High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 673 | 661 | 8356 | 21692 | 629.4 | 88.97 | 157.77 | 200.04 | 505 | 558 | 588 | 612 | 637 | 660 | 678 | 703 | 736 | 0.0423 | 917 | 1.088 | 108.30 | 37.05 | 1 | 0.0333 | 278 | 0.0009 | 30.54 | 7.337 | 0.2196 | 404042.0 | 264000000 | 175000000000 | 118000000000000 | 0.4222 | 0.2219 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0036 | 0.0002 | 0.0168 | 0.0091 | 0.0339 | 0.0170 | 0.0309 | 0.0087 | 0.0431 | 0.0141 | 0.8703 | 0.9508 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0017 | 0.0002 | 0.0097 | 0.0091 | 0.0211 | 0.0170 | 0.0174 | 0.0087 | 0.0212 | 0.0141 | 0.9286 | 0.9508 | 0.0052 | 0.0000 | 0.0087 | 0.0000 | 0.0280 | 0.0000 | 0.0332 | 0.0000 | 0.0769 | 0.0000 | 0.1206 | 0.0000 | 0.0962 | 0.0000 | 0.1521 | 0.0000 | 0.4790 | 0.0000 | 0.0011 | 0.0031 | 0.0058 | 0.0105 | 0.0285 | 0.0524 | 0.0515 | 0.0731 | 0.7740 | 10 | 13 | 19 | 33 | 63 | 113 | 189 | 289 | 461 | 0.0633 | 29.43 | 5.277 | 0.5302 | 64906.9 | 36700000 | 24600000000 | 18400000000000 | 0.4278 | 0.2001 | 0.0270 | 0.0020 | 0.1224 | 0.0151 | 0.2282 | 0.0660 | 0.1787 | 0.1115 | 0.1483 | 0.1596 | 0.1201 | 0.2156 | 0.0684 | 0.1388 | 0.0615 | 0.1073 | 0.0454 | 0.1841 | 0.0001 | 0.0003 | 0.0002 | 0.0008 | 0.0015 | 0.0014 | 0.0077 | 0.0098 | 0.0437 | 0.0330 | 0.0678 | 0.0540 | 0.0479 | 0.0450 | 0.0793 | 0.0589 | 0.7519 | 0.7967 | 0.0005 | 0.0000 | 0.0015 | 0.0012 | 0.0026 | 0.0031 | 0.0122 | 0.0151 | 0.0611 | 0.0727 | 0.0953 | 0.1124 | 0.0662 | 0.0769 | 0.1035 | 0.1141 | 0.6570 | 0.6045 | 0.0001 | 0.0010 | 0.0024 | 0.0121 | 0.0486 | 0.0835 | 0.0554 | 0.0881 | 0.7087 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 662 | 697 | 5913 | 18261 | 491.0 | 67.94 | 138.35 | 220.58 | 396 | 436 | 462 | 484 | 500 | 513 | 528 | 544 | 572 | 0.0451 | 824 | 1.176 | 94.54 | 34.99 | 1 | 0.0404 | 239 | 0.0021 | 16.68 | 6.549 | 0.2788 | 245703.0 | 125000000 | 64600000000 | 33900000000000 | 0.4193 | 0.2254 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0010 | 0.0000 | 0.0052 | 0.0002 | 0.0206 | 0.0107 | 0.0401 | 0.0231 | 0.0409 | 0.0105 | 0.0497 | 0.0178 | 0.8421 | 0.9378 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0011 | 0.0002 | 0.0140 | 0.0105 | 0.0257 | 0.0222 | 0.0200 | 0.0095 | 0.0276 | 0.0162 | 0.9112 | 0.9414 | 0.0028 | 0.0000 | 0.0142 | 0.1111 | 0.0426 | 0.1111 | 0.0767 | 0.1111 | 0.1392 | 0.4444 | 0.1193 | 0.2222 | 0.1193 | 0.0000 | 0.1591 | 0.0000 | 0.3267 | 0.0000 | 0.0003 | 0.0033 | 0.0069 | 0.0169 | 0.0350 | 0.0555 | 0.0628 | 0.0872 | 0.7320 | 8 | 10 | 12 | 16 | 27 | 52 | 112 | 246 | 464 | 0.1339 | 21.44 | 4.364 | 0.6125 | 67793.0 | 46900000 | 38600000000 | 36000000000000 | 0.3682 | 0.2671 | 0.0646 | 0.0035 | 0.1579 | 0.0234 | 0.2759 | 0.1034 | 0.1692 | 0.1313 | 0.1344 | 0.1895 | 0.0985 | 0.2004 | 0.0595 | 0.1034 | 0.0236 | 0.1193 | 0.0164 | 0.1258 | 0.0004 | 0.0006 | 0.0011 | 0.0015 | 0.0025 | 0.0023 | 0.0114 | 0.0085 | 0.0461 | 0.0447 | 0.0764 | 0.0614 | 0.0517 | 0.0432 | 0.0719 | 0.0705 | 0.7384 | 0.7673 | 0.0011 | 0.0005 | 0.0009 | 0.0007 | 0.0026 | 0.0033 | 0.0168 | 0.0158 | 0.0521 | 0.0575 | 0.0907 | 0.0945 | 0.0618 | 0.0628 | 0.0783 | 0.0833 | 0.6958 | 0.6816 | 0.0006 | 0.0014 | 0.0028 | 0.0152 | 0.0474 | 0.0861 | 0.0548 | 0.0734 | 0.7183 | |||
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 692 | 185 | 19415 | 44441 | 368.7 | 56.02 | 244.04 | 276.54 | 299 | 324 | 341 | 357 | 370 | 384 | 398 | 414 | 438 | 0.0403 | 1792 | 0.714 | 124.33 | 24.70 | 1 | 0.0157 | 305 | 0.0014 | 22.18 | 6.923 | 0.2357 | 139081.0 | 53500000 | 21000000000 | 8390000000000 | 0.4311 | 0.2269 | 0.0001 | 0.0000 | 0.0008 | 0.0001 | 0.0028 | 0.0001 | 0.0066 | 0.0002 | 0.0259 | 0.0087 | 0.0530 | 0.0182 | 0.0576 | 0.0109 | 0.0865 | 0.0176 | 0.7667 | 0.9443 | 0.0001 | 0.0000 | 0.0004 | 0.0001 | 0.0011 | 0.0001 | 0.0033 | 0.0002 | 0.0141 | 0.0084 | 0.0282 | 0.0172 | 0.0273 | 0.0090 | 0.0375 | 0.0134 | 0.8880 | 0.9517 | 0.0119 | 0.0000 | 0.0209 | 0.0000 | 0.0346 | 0.0000 | 0.0930 | 0.0000 | 0.1169 | 0.0000 | 0.1574 | 0.0000 | 0.1199 | 0.0000 | 0.1306 | 0.0000 | 0.3148 | 0.0000 | 0.0012 | 0.0035 | 0.0100 | 0.0254 | 0.0509 | 0.0848 | 0.0988 | 0.1192 | 0.6061 | 17 | 22 | 30 | 54 | 118 | 220 | 341 | 473 | 647 | 0.0281 | 44.65 | 6.124 | 0.4266 | 136024.0 | 100000000 | 87800000000 | 88300000000000 | 0.4534 | 0.1804 | 0.0700 | 0.0020 | 0.2411 | 0.0134 | 0.3304 | 0.1499 | 0.1469 | 0.1951 | 0.0898 | 0.2149 | 0.0610 | 0.1886 | 0.0354 | 0.0976 | 0.0173 | 0.0724 | 0.0080 | 0.0662 | 0.0003 | 0.0002 | 0.0010 | 0.0004 | 0.0018 | 0.0013 | 0.0092 | 0.0076 | 0.0506 | 0.0416 | 0.1014 | 0.0881 | 0.0667 | 0.0543 | 0.0944 | 0.0803 | 0.6746 | 0.7262 | 0.0007 | 0.0004 | 0.0014 | 0.0017 | 0.0031 | 0.0043 | 0.0147 | 0.0194 | 0.0670 | 0.0789 | 0.1259 | 0.1392 | 0.0883 | 0.0943 | 0.1136 | 0.1275 | 0.5852 | 0.5343 | 0.0001 | 0.0007 | 0.0030 | 0.0105 | 0.0587 | 0.1131 | 0.0775 | 0.1049 | 0.6315 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 889 | 579 | 5344 | 14258 | 479.3 | 73.36 | 59.66 | 126.81 | 384 | 417 | 439 | 460 | 479 | 496 | 514 | 540 | 582 | 0.0560 | 799 | 1.214 | 72.84 | 31.83 | 1 | 0.0378 | 202 | 0.0020 | 11.27 | 6.511 | 0.3208 | 235079.0 | 118000000 | 60300000000 | 31500000000000 | 0.4020 | 0.2453 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0066 | 0.0002 | 0.0216 | 0.0122 | 0.0337 | 0.0213 | 0.0309 | 0.0112 | 0.0475 | 0.0182 | 0.8575 | 0.9369 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0002 | 0.0127 | 0.0122 | 0.0206 | 0.0213 | 0.0145 | 0.0112 | 0.0247 | 0.0167 | 0.9252 | 0.9384 | 0.0000 | 1.0000 | 0.0232 | 0.0000 | 0.0066 | 0.0000 | 0.0381 | 0.0000 | 0.0381 | 0.0000 | 0.0614 | 0.0000 | 0.0779 | 0.0000 | 0.0962 | 0.0000 | 0.6584 | 0.0000 | 0.0019 | 0.0026 | 0.0071 | 0.0160 | 0.0360 | 0.0527 | 0.0605 | 0.0854 | 0.7379 | 6 | 7 | 8 | 9 | 11 | 14 | 23 | 58 | 184 | 0.1961 | 6.16 | 3.029 | 0.6633 | 19637.6 | 11000000 | 8130000000 | 7350000000000 | 0.5394 | 0.1197 | 0.0721 | 0.0088 | 0.1081 | 0.0431 | 0.2450 | 0.1186 | 0.1766 | 0.0958 | 0.1315 | 0.1511 | 0.1045 | 0.1722 | 0.0829 | 0.1178 | 0.0541 | 0.1283 | 0.0252 | 0.1643 | 0.0010 | 0.0000 | 0.0013 | 0.0011 | 0.0048 | 0.0056 | 0.0166 | 0.0189 | 0.0507 | 0.0498 | 0.0842 | 0.0715 | 0.0555 | 0.0540 | 0.0778 | 0.0791 | 0.7083 | 0.7200 | 0.0008 | 0.0004 | 0.0027 | 0.0029 | 0.0023 | 0.0037 | 0.0139 | 0.0166 | 0.0616 | 0.0605 | 0.0953 | 0.0957 | 0.0581 | 0.0609 | 0.0817 | 0.0787 | 0.6836 | 0.6807 | 0.0007 | 0.0021 | 0.0021 | 0.0220 | 0.0535 | 0.0839 | 0.0676 | 0.0740 | 0.6941 | |||
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1020 | 437 | 7708 | 18612 | 422.4 | 67.92 | 139.42 | 205.57 | 338 | 363 | 382 | 400 | 419 | 436 | 456 | 480 | 516 | 0.0529 | 985 | 1.200 | 83.10 | 36.12 | 1 | 0.0294 | 227 | 0.0008 | 46.82 | 7.310 | 0.1734 | 183017.0 | 81300000 | 37000000000 | 17200000000000 | 0.4380 | 0.2129 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0001 | 0.0063 | 0.0003 | 0.0381 | 0.0119 | 0.0754 | 0.0187 | 0.0832 | 0.0153 | 0.1243 | 0.0245 | 0.6713 | 0.9293 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0001 | 0.0203 | 0.0112 | 0.0379 | 0.0157 | 0.0403 | 0.0104 | 0.0599 | 0.0156 | 0.8392 | 0.9471 | 0.0075 | 0.0000 | 0.0118 | 0.0000 | 0.0236 | 0.0000 | 0.0675 | 0.0000 | 0.1263 | 0.0000 | 0.1649 | 0.0000 | 0.1113 | 0.0000 | 0.1349 | 0.0000 | 0.3522 | 0.0000 | 0.0013 | 0.0019 | 0.0078 | 0.0317 | 0.0666 | 0.1048 | 0.1005 | 0.1115 | 0.5740 | 10 | 12 | 14 | 18 | 26 | 54 | 132 | 275 | 460 | 0.1177 | 30.91 | 4.625 | 0.5832 | 61695.7 | 37000000 | 26000000000 | 20500000000000 | 0.5639 | 0.1251 | 0.1199 | 0.0027 | 0.3225 | 0.0469 | 0.2770 | 0.2340 | 0.1271 | 0.2073 | 0.0875 | 0.1942 | 0.0372 | 0.1189 | 0.0168 | 0.0802 | 0.0108 | 0.0627 | 0.0012 | 0.0529 | 0.0002 | 0.0000 | 0.0010 | 0.0012 | 0.0020 | 0.0017 | 0.0102 | 0.0098 | 0.0543 | 0.0504 | 0.0817 | 0.0716 | 0.0611 | 0.0529 | 0.0974 | 0.0820 | 0.6921 | 0.7303 | 0.0002 | 0.0004 | 0.0018 | 0.0028 | 0.0035 | 0.0030 | 0.0106 | 0.0119 | 0.0670 | 0.0774 | 0.1038 | 0.1070 | 0.0723 | 0.0864 | 0.1182 | 0.1269 | 0.6226 | 0.5842 | 0.0000 | 0.0009 | 0.0026 | 0.0119 | 0.0552 | 0.1008 | 0.0649 | 0.1025 | 0.6613 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 489 | 816 | 9613 | 19666 | 390.1 | 60.27 | 175.40 | 251.54 | 316 | 341 | 358 | 372 | 386 | 400 | 417 | 439 | 471 | 0.0499 | 981 | 1.140 | 113.53 | 39.96 | 1 | 0.0287 | 276 | 0.0011 | 38.49 | 7.151 | 0.1882 | 155802.0 | 63700000 | 26600000000 | 11400000000000 | 0.4343 | 0.2166 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0063 | 0.0003 | 0.0283 | 0.0097 | 0.0643 | 0.0203 | 0.0756 | 0.0131 | 0.1055 | 0.0246 | 0.7186 | 0.9320 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0028 | 0.0001 | 0.0131 | 0.0084 | 0.0304 | 0.0170 | 0.0306 | 0.0084 | 0.0456 | 0.0152 | 0.8770 | 0.9508 | 0.0087 | 0.0000 | 0.0135 | 0.0000 | 0.0279 | 0.0000 | 0.0983 | 0.0000 | 0.1387 | 0.0000 | 0.1513 | 0.0000 | 0.1416 | 0.0000 | 0.1262 | 0.0000 | 0.2938 | 0.0000 | 0.0011 | 0.0035 | 0.0104 | 0.0298 | 0.0782 | 0.1108 | 0.1017 | 0.1210 | 0.5436 | 14 | 16 | 20 | 33 | 69 | 120 | 189 | 295 | 474 | 0.0394 | 31.15 | 5.368 | 0.5068 | 94034.5 | 84100000 | 103000000000 | 154000000000000 | 0.3897 | 0.2589 | 0.0213 | 0.0011 | 0.1385 | 0.0082 | 0.2420 | 0.0616 | 0.1776 | 0.1065 | 0.1672 | 0.1616 | 0.1236 | 0.1947 | 0.0759 | 0.1312 | 0.0374 | 0.1260 | 0.0167 | 0.2092 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0018 | 0.0009 | 0.0087 | 0.0075 | 0.0520 | 0.0374 | 0.0873 | 0.0660 | 0.0601 | 0.0490 | 0.0912 | 0.0703 | 0.6988 | 0.7683 | 0.0002 | 0.0002 | 0.0016 | 0.0006 | 0.0035 | 0.0034 | 0.0199 | 0.0226 | 0.0723 | 0.0866 | 0.1159 | 0.1289 | 0.0783 | 0.0860 | 0.1143 | 0.1210 | 0.5940 | 0.5507 | 0.0000 | 0.0008 | 0.0022 | 0.0144 | 0.0633 | 0.0998 | 0.0700 | 0.1025 | 0.6469 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 292 | 776 | 6777 | 12524 | 325.6 | 51.91 | 172.85 | 222.30 | 258 | 277 | 296 | 311 | 323 | 337 | 352 | 369 | 393 | 0.0787 | 986 | 1.019 | 135.34 | 41.01 | 1 | 0.0484 | 328 | 0.0017 | 16.93 | 6.629 | 0.2646 | 108700.0 | 37200000 | 13000000000 | 4670000000000 | 0.3905 | 0.2545 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0036 | 0.0001 | 0.0131 | 0.0003 | 0.0300 | 0.0124 | 0.0571 | 0.0234 | 0.0742 | 0.0142 | 0.0991 | 0.0285 | 0.7210 | 0.9211 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0000 | 0.0071 | 0.0001 | 0.0167 | 0.0114 | 0.0295 | 0.0193 | 0.0326 | 0.0106 | 0.0443 | 0.0171 | 0.8660 | 0.9414 | 0.0057 | 0.0000 | 0.0114 | 0.0000 | 0.0341 | 0.0000 | 0.0994 | 0.0000 | 0.0994 | 0.0000 | 0.1605 | 0.0000 | 0.1179 | 0.0000 | 0.1264 | 0.0000 | 0.3452 | 0.0000 | 0.0015 | 0.0034 | 0.0073 | 0.0208 | 0.0531 | 0.0784 | 0.0815 | 0.1227 | 0.6313 | 14 | 16 | 19 | 25 | 51 | 113 | 215 | 343 | 515 | 0.0450 | 24.78 | 5.251 | 0.4914 | 79286.9 | 49200000 | 36500000000 | 31300000000000 | 0.4891 | 0.1521 | 0.0682 | 0.0006 | 0.2302 | 0.0144 | 0.3264 | 0.1428 | 0.1949 | 0.1888 | 0.1084 | 0.2199 | 0.0560 | 0.1929 | 0.0097 | 0.1180 | 0.0049 | 0.0760 | 0.0012 | 0.0466 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0015 | 0.0099 | 0.0101 | 0.0578 | 0.0482 | 0.0893 | 0.0778 | 0.0562 | 0.0523 | 0.0885 | 0.0782 | 0.6971 | 0.7317 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0023 | 0.0032 | 0.0138 | 0.0193 | 0.0706 | 0.0776 | 0.1115 | 0.1144 | 0.0701 | 0.0761 | 0.0996 | 0.1129 | 0.6310 | 0.5957 | 0.0000 | 0.0000 | 0.0012 | 0.0129 | 0.0628 | 0.1014 | 0.0584 | 0.0960 | 0.6673 | |
SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 969 | 728 | 16378 | 49009 | 195.5 | 37.68 | 203.96 | 331.62 | 151 | 169 | 180 | 189 | 198 | 206 | 215 | 226 | 241 | 0.0278 | 1362 | 1.188 | 93.09 | 34.48 | 1 | 0.0143 | 235 | 0.0032 | 12.80 | 6.161 | 0.3225 | 39638.5 | 8270000 | 1770000000 | 387000000000 | 0.4222 | 0.2262 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0037 | 0.0000 | 0.0129 | 0.0003 | 0.0346 | 0.0080 | 0.0661 | 0.0181 | 0.0824 | 0.0160 | 0.1152 | 0.0268 | 0.6836 | 0.9309 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0036 | 0.0001 | 0.0120 | 0.0068 | 0.0260 | 0.0139 | 0.0283 | 0.0069 | 0.0418 | 0.0107 | 0.8870 | 0.9616 | 0.0089 | 0.0576 | 0.0166 | 0.0995 | 0.0426 | 0.1047 | 0.0736 | 0.1780 | 0.1192 | 0.1937 | 0.1473 | 0.1675 | 0.1256 | 0.0733 | 0.1456 | 0.0890 | 0.3206 | 0.0366 | 0.0012 | 0.0027 | 0.0072 | 0.0202 | 0.0501 | 0.0834 | 0.0821 | 0.1197 | 0.6333 | 7 | 8 | 10 | 12 | 17 | 54 | 192 | 390 | 701 | 0.1432 | 35.53 | 4.788 | 0.5519 | 151568.0 | 149000000 | 169000000000 | 211000000000000 | 0.4292 | 0.2197 | 0.0529 | 0.0035 | 0.2034 | 0.0131 | 0.2775 | 0.1127 | 0.1544 | 0.1604 | 0.1262 | 0.2014 | 0.0909 | 0.1979 | 0.0516 | 0.1081 | 0.0322 | 0.1003 | 0.0110 | 0.1027 | 0.0001 | 0.0001 | 0.0003 | 0.0001 | 0.0010 | 0.0003 | 0.0081 | 0.0057 | 0.0395 | 0.0371 | 0.0691 | 0.0641 | 0.0487 | 0.0414 | 0.0700 | 0.0648 | 0.7633 | 0.7864 | 0.0004 | 0.0003 | 0.0011 | 0.0011 | 0.0028 | 0.0036 | 0.0129 | 0.0138 | 0.0452 | 0.0466 | 0.0753 | 0.0825 | 0.0565 | 0.0561 | 0.0729 | 0.0789 | 0.7329 | 0.7170 | 0.0001 | 0.0013 | 0.0022 | 0.0102 | 0.0423 | 0.0730 | 0.0512 | 0.0723 | 0.7473 | |
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 149 | 240 | 6671 | 12334 | 390.0 | 50.74 | 109.56 | 270.04 | 317 | 352 | 374 | 389 | 399 | 409 | 419 | 431 | 446 | 0.0712 | 878 | 0.700 | 125.40 | 29.61 | 3 | 0.0475 | 317 | 0.0019 | 22.81 | 6.624 | 0.2349 | 154695.0 | 62200000 | 25300000000 | 10400000000000 | 0.4580 | 0.1948 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0037 | 0.0003 | 0.0169 | 0.0112 | 0.0407 | 0.0210 | 0.0412 | 0.0134 | 0.0715 | 0.0187 | 0.8249 | 0.9354 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0023 | 0.0003 | 0.0133 | 0.0112 | 0.0316 | 0.0210 | 0.0235 | 0.0134 | 0.0319 | 0.0187 | 0.8969 | 0.9354 | 0.1176 | 0.0000 | 0.1438 | 0.0000 | 0.1373 | 0.0000 | 0.1830 | 0.0000 | 0.1111 | 0.0000 | 0.1569 | 0.0000 | 0.0261 | 0.0000 | 0.0523 | 0.0000 | 0.0719 | 0.0000 | 0.0020 | 0.0033 | 0.0091 | 0.0202 | 0.0463 | 0.0663 | 0.0825 | 0.1189 | 0.6514 | 9 | 11 | 12 | 14 | 15 | 18 | 24 | 59 | 344 | 0.2142 | 6.81 | 2.736 | 0.6641 | 84919.1 | 101000000 | 144000000000 | 229000000000000 | 0.5929 | 0.1077 | 0.0204 | 0.0068 | 0.0980 | 0.0068 | 0.1592 | 0.0492 | 0.1878 | 0.0881 | 0.2082 | 0.1593 | 0.1755 | 0.1864 | 0.1020 | 0.1203 | 0.0367 | 0.1661 | 0.0122 | 0.2169 | 0.0005 | 0.0017 | 0.0019 | 0.0004 | 0.0014 | 0.0034 | 0.0052 | 0.0085 | 0.0331 | 0.0296 | 0.0553 | 0.0525 | 0.0355 | 0.0407 | 0.0766 | 0.0805 | 0.7905 | 0.7827 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0021 | 0.0017 | 0.0064 | 0.0079 | 0.0380 | 0.0350 | 0.0545 | 0.0599 | 0.0401 | 0.0418 | 0.0866 | 0.0870 | 0.7722 | 0.7662 | 0.0000 | 0.0000 | 0.0020 | 0.0076 | 0.0289 | 0.0613 | 0.0370 | 0.0770 | 0.7863 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 634 | 836 | 6694 | 23123 | 220.1 | 45.92 | 161.99 | 175.74 | 165 | 181 | 193 | 204 | 215 | 227 | 240 | 256 | 280 | 0.0480 | 1111 | 1.210 | 102.65 | 44.29 | 1 | 0.0420 | 281 | 0.0011 | 40.91 | 7.097 | 0.1838 | 50535.0 | 12100000 | 3040000000 | 797000000000 | 0.4401 | 0.2135 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0029 | 0.0002 | 0.0159 | 0.0003 | 0.0615 | 0.0172 | 0.1197 | 0.0311 | 0.1488 | 0.0369 | 0.1834 | 0.0515 | 0.4669 | 0.8628 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0062 | 0.0000 | 0.0277 | 0.0126 | 0.0551 | 0.0171 | 0.0627 | 0.0163 | 0.0885 | 0.0249 | 0.7582 | 0.9291 | 0.0046 | 0.0108 | 0.0147 | 0.0179 | 0.0394 | 0.0502 | 0.0879 | 0.1613 | 0.1319 | 0.1613 | 0.1712 | 0.1864 | 0.1071 | 0.1111 | 0.1328 | 0.0932 | 0.3104 | 0.2079 | 0.0013 | 0.0016 | 0.0090 | 0.0303 | 0.0940 | 0.1211 | 0.1137 | 0.1523 | 0.4767 | 11 | 13 | 18 | 38 | 92 | 162 | 235 | 308 | 417 | 0.0450 | 24.09 | 5.615 | 0.4490 | 57122.6 | 25900000 | 13700000000 | 8060000000000 | 0.4415 | 0.1960 | 0.0450 | 0.0017 | 0.1921 | 0.0096 | 0.3192 | 0.0939 | 0.1711 | 0.1707 | 0.1124 | 0.2071 | 0.0816 | 0.1996 | 0.0401 | 0.1194 | 0.0308 | 0.1084 | 0.0078 | 0.0896 | 0.0005 | 0.0001 | 0.0009 | 0.0005 | 0.0008 | 0.0016 | 0.0092 | 0.0074 | 0.0453 | 0.0386 | 0.0833 | 0.0715 | 0.0621 | 0.0516 | 0.0918 | 0.0767 | 0.7061 | 0.7520 | 0.0001 | 0.0007 | 0.0010 | 0.0017 | 0.0034 | 0.0074 | 0.0198 | 0.0214 | 0.0603 | 0.0717 | 0.1056 | 0.1113 | 0.0810 | 0.0864 | 0.1068 | 0.1131 | 0.6220 | 0.5862 | 0.0001 | 0.0006 | 0.0018 | 0.0130 | 0.0555 | 0.0911 | 0.0731 | 0.1019 | 0.6628 | |
MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 307 | 653 | 10385 | 21337 | 574.1 | 114.46 | 155.18 | 135.73 | 433 | 473 | 505 | 535 | 564 | 596 | 628 | 670 | 733 | 0.0486 | 1036 | 0.577 | 103.02 | 13.04 | 1 | 0.0206 | 214 | 0.0007 | 50.52 | 7.494 | 0.1652 | 342696.0 | 212000000 | 136000000000 | 90600000000000 | 0.4477 | 0.1993 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0000 | 0.0114 | 0.0003 | 0.0529 | 0.0143 | 0.1183 | 0.0275 | 0.1255 | 0.0275 | 0.1535 | 0.0489 | 0.5362 | 0.8814 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0000 | 0.0053 | 0.0001 | 0.0241 | 0.0099 | 0.0493 | 0.0168 | 0.0533 | 0.0122 | 0.0720 | 0.0203 | 0.7946 | 0.9407 | 0.0023 | 0.0176 | 0.0082 | 0.0265 | 0.0164 | 0.0676 | 0.0614 | 0.1088 | 0.1392 | 0.2118 | 0.1766 | 0.2000 | 0.1094 | 0.1294 | 0.1433 | 0.1235 | 0.3433 | 0.1147 | 0.0008 | 0.0010 | 0.0049 | 0.0246 | 0.0722 | 0.1181 | 0.0958 | 0.1311 | 0.5515 | 25 | 42 | 64 | 88 | 118 | 150 | 191 | 249 | 337 | 0.0077 | 23.32 | 5.939 | 0.3643 | 42503.4 | 16400000 | 8080000000 | 4790000000000 | 0.5282 | 0.1429 | 0.0347 | 0.0014 | 0.1391 | 0.0079 | 0.2389 | 0.0792 | 0.1810 | 0.1231 | 0.1607 | 0.1736 | 0.1170 | 0.1882 | 0.0714 | 0.1466 | 0.0353 | 0.1335 | 0.0219 | 0.1463 | 0.0005 | 0.0002 | 0.0011 | 0.0004 | 0.0042 | 0.0024 | 0.0233 | 0.0140 | 0.0793 | 0.0638 | 0.1263 | 0.0985 | 0.1017 | 0.0802 | 0.1398 | 0.1307 | 0.5240 | 0.6098 | 0.0009 | 0.0039 | 0.0053 | 0.0039 | 0.0117 | 0.0141 | 0.0449 | 0.0589 | 0.1098 | 0.1287 | 0.1665 | 0.1769 | 0.1228 | 0.1268 | 0.1550 | 0.1577 | 0.3832 | 0.3291 | 0.0010 | 0.0024 | 0.0071 | 0.0342 | 0.0973 | 0.1484 | 0.1159 | 0.1555 | 0.4382 | |
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 739 | 828 | 3336 | 10996 | 733.4 | 131.67 | 162.29 | 302.51 | 560 | 619 | 661 | 696 | 729 | 766 | 805 | 848 | 907 | 0.0851 | 936 | 1.020 | 70.01 | 22.36 | 1 | 0.0525 | 175 | 0.0011 | 45.93 | 7.024 | 0.1864 | 555153.0 | 433000000 | 346000000000 | 284000000000000 | 0.4491 | 0.1924 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0070 | 0.0003 | 0.0488 | 0.0168 | 0.1141 | 0.0324 | 0.0930 | 0.0251 | 0.1439 | 0.0321 | 0.5920 | 0.8934 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0003 | 0.0255 | 0.0157 | 0.0541 | 0.0275 | 0.0375 | 0.0151 | 0.0620 | 0.0236 | 0.8185 | 0.9178 | 0.0041 | 0.0000 | 0.0000 | 0.0541 | 0.0269 | 0.1081 | 0.0579 | 0.2432 | 0.1467 | 0.1892 | 0.2004 | 0.2973 | 0.1240 | 0.0270 | 0.1508 | 0.0541 | 0.2893 | 0.0270 | 0.0000 | 0.0025 | 0.0105 | 0.0215 | 0.0732 | 0.0942 | 0.0905 | 0.1046 | 0.6031 | 8 | 10 | 11 | 12 | 14 | 20 | 71 | 262 | 593 | 0.2612 | 53.14 | 3.819 | 0.6522 | 117840.0 | 116000000 | 132000000000 | 164000000000000 | 0.5865 | 0.0859 | 0.1144 | 0.0083 | 0.2779 | 0.0904 | 0.2861 | 0.2629 | 0.1417 | 0.1599 | 0.1063 | 0.1460 | 0.0436 | 0.1252 | 0.0272 | 0.0918 | 0.0027 | 0.0668 | 0.0000 | 0.0487 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0007 | 0.0007 | 0.0093 | 0.0101 | 0.0593 | 0.0520 | 0.1052 | 0.1002 | 0.0576 | 0.0598 | 0.1014 | 0.0881 | 0.6657 | 0.6888 | 0.0000 | 0.0008 | 0.0008 | 0.0013 | 0.0024 | 0.0051 | 0.0154 | 0.0166 | 0.0675 | 0.0696 | 0.1110 | 0.1099 | 0.0667 | 0.0743 | 0.1082 | 0.1002 | 0.6280 | 0.6222 | 0.0000 | 0.0007 | 0.0011 | 0.0136 | 0.0618 | 0.1045 | 0.0674 | 0.0986 | 0.6522 | |
MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 755 | 233 | 6882 | 11035 | 750.8 | 130.11 | 50.30 | 107.22 | 589 | 637 | 676 | 712 | 743 | 780 | 818 | 862 | 917 | 0.0847 | 935 | 0.936 | 120.35 | 37.05 | 2 | 0.0442 | 304 | 0.0010 | 30.30 | 7.224 | 0.2258 | 580634.0 | 462000000 | 378000000000 | 319000000000000 | 0.4407 | 0.2046 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0019 | 0.0001 | 0.0078 | 0.0003 | 0.0358 | 0.0142 | 0.0524 | 0.0228 | 0.0553 | 0.0152 | 0.0717 | 0.0231 | 0.7735 | 0.9243 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0031 | 0.0003 | 0.0186 | 0.0130 | 0.0277 | 0.0192 | 0.0279 | 0.0119 | 0.0379 | 0.0175 | 0.8843 | 0.9381 | 0.0012 | 0.0000 | 0.0048 | 0.0000 | 0.0203 | 0.0102 | 0.0501 | 0.1122 | 0.0776 | 0.0918 | 0.1241 | 0.1531 | 0.1181 | 0.1122 | 0.1050 | 0.1429 | 0.4988 | 0.3776 | 0.0009 | 0.0021 | 0.0039 | 0.0173 | 0.0318 | 0.0500 | 0.0518 | 0.0760 | 0.7662 | 7 | 9 | 11 | 12 | 15 | 19 | 26 | 42 | 126 | 0.0842 | 13.28 | 3.740 | 0.6597 | 14024.1 | 7570000 | 5380000000 | 4510000000000 | 0.4239 | 0.2208 | 0.0278 | 0.0089 | 0.0872 | 0.0149 | 0.1930 | 0.0343 | 0.1818 | 0.0961 | 0.1781 | 0.1586 | 0.1447 | 0.1571 | 0.1095 | 0.1400 | 0.0538 | 0.1482 | 0.0241 | 0.2420 | 0.0017 | 0.0034 | 0.0022 | 0.0044 | 0.0074 | 0.0065 | 0.0288 | 0.0266 | 0.0616 | 0.0536 | 0.0634 | 0.0615 | 0.0621 | 0.0663 | 0.0743 | 0.0844 | 0.6984 | 0.6933 | 0.0000 | 0.0013 | 0.0011 | 0.0013 | 0.0046 | 0.0019 | 0.0194 | 0.0183 | 0.0549 | 0.0593 | 0.0800 | 0.0732 | 0.0446 | 0.0511 | 0.0652 | 0.0650 | 0.7301 | 0.7287 | 0.0015 | 0.0025 | 0.0041 | 0.0259 | 0.0498 | 0.0747 | 0.0503 | 0.0711 | 0.7202 | |
MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1110 | 757 | 3351 | 8311 | 502.7 | 95.67 | 33.73 | 39.62 | 357 | 407 | 453 | 492 | 521 | 545 | 571 | 592 | 615 | 0.0870 | 723 | 0.586 | 94.34 | 18.44 | 4 | 0.0800 | 268 | 0.0017 | 22.52 | 6.640 | 0.2618 | 261823.0 | 140000000 | 77100000000 | 43100000000000 | 0.4208 | 0.2054 | 0.0009 | 0.0000 | 0.0018 | 0.0000 | 0.0032 | 0.0000 | 0.0126 | 0.0003 | 0.0519 | 0.0230 | 0.0992 | 0.0385 | 0.0767 | 0.0212 | 0.1164 | 0.0333 | 0.6373 | 0.8836 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0033 | 0.0003 | 0.0258 | 0.0230 | 0.0508 | 0.0385 | 0.0309 | 0.0212 | 0.0416 | 0.0333 | 0.8475 | 0.8836 | 0.0040 | 0.0000 | 0.0100 | 0.0000 | 0.0562 | 0.0000 | 0.0462 | 0.0000 | 0.0884 | 0.0000 | 0.1486 | 0.0000 | 0.1245 | 0.0000 | 0.1365 | 0.0000 | 0.3855 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0105 | 0.0374 | 0.0664 | 0.0485 | 0.0822 | 0.7533 | 6 | 9 | 12 | 17 | 22 | 27 | 35 | 48 | 73 | 0.0559 | 2.46 | 3.830 | 0.6657 | 2706.9 | 419279 | 98900000 | 30200000000 | 0.4904 | 0.1617 | 0.0258 | 0.0068 | 0.0646 | 0.0188 | 0.1025 | 0.0315 | 0.1291 | 0.0630 | 0.1646 | 0.0926 | 0.1542 | 0.1197 | 0.1703 | 0.1268 | 0.1219 | 0.1707 | 0.0670 | 0.3702 | 0.0043 | 0.0037 | 0.0109 | 0.0089 | 0.0173 | 0.0103 | 0.0261 | 0.0233 | 0.0480 | 0.0423 | 0.0690 | 0.0618 | 0.0693 | 0.0622 | 0.0976 | 0.0913 | 0.6574 | 0.6962 | 0.0015 | 0.0023 | 0.0102 | 0.0059 | 0.0171 | 0.0147 | 0.0297 | 0.0282 | 0.0585 | 0.0639 | 0.0848 | 0.0886 | 0.0692 | 0.0745 | 0.1053 | 0.1003 | 0.6236 | 0.6217 | 0.0050 | 0.0123 | 0.0204 | 0.0316 | 0.0500 | 0.0750 | 0.0685 | 0.0927 | 0.6445 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1097 | 888 | 12238 | 26075 | 289.7 | 37.50 | 189.36 | 227.04 | 244 | 259 | 270 | 279 | 288 | 297 | 306 | 319 | 339 | 0.0439 | 1145 | 0.830 | 88.09 | 22.20 | 1 | 0.0187 | 229 | 0.0028 | 13.76 | 6.262 | 0.2992 | 85311.3 | 25500000 | 7770000000 | 2410000000000 | 0.4323 | 0.2203 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0020 | 0.0000 | 0.0060 | 0.0003 | 0.0185 | 0.0078 | 0.0396 | 0.0156 | 0.0439 | 0.0098 | 0.0748 | 0.0169 | 0.8146 | 0.9496 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0001 | 0.0111 | 0.0076 | 0.0227 | 0.0147 | 0.0220 | 0.0071 | 0.0372 | 0.0112 | 0.9046 | 0.9593 | 0.0133 | 0.0000 | 0.0200 | 0.0000 | 0.0333 | 0.0000 | 0.0765 | 0.0000 | 0.1109 | 0.0000 | 0.1408 | 0.0000 | 0.1264 | 0.0000 | 0.1574 | 0.0000 | 0.3215 | 0.0000 | 0.0025 | 0.0088 | 0.0142 | 0.0239 | 0.0616 | 0.0902 | 0.0999 | 0.1291 | 0.5696 | 14 | 17 | 21 | 38 | 82 | 149 | 243 | 368 | 535 | 0.0346 | 41.52 | 5.730 | 0.4531 | 87402.9 | 53700000 | 38800000000 | 31400000000000 | 0.4360 | 0.2156 | 0.0618 | 0.0023 | 0.2087 | 0.0236 | 0.2420 | 0.1370 | 0.1346 | 0.1541 | 0.1098 | 0.1754 | 0.0927 | 0.1578 | 0.0590 | 0.0979 | 0.0495 | 0.0906 | 0.0418 | 0.1614 | 0.0001 | 0.0003 | 0.0003 | 0.0006 | 0.0015 | 0.0013 | 0.0103 | 0.0092 | 0.0495 | 0.0407 | 0.0808 | 0.0715 | 0.0648 | 0.0501 | 0.0944 | 0.0787 | 0.6983 | 0.7478 | 0.0000 | 0.0003 | 0.0007 | 0.0015 | 0.0026 | 0.0033 | 0.0159 | 0.0223 | 0.0664 | 0.0710 | 0.1136 | 0.1319 | 0.0845 | 0.0978 | 0.1225 | 0.1311 | 0.5939 | 0.5409 | 0.0004 | 0.0007 | 0.0021 | 0.0134 | 0.0562 | 0.0948 | 0.0755 | 0.1060 | 0.6510 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 387 | 777 | 3566 | 6931 | 639.4 | 107.04 | 10.06 | 4.66 | 486 | 547 | 588 | 620 | 651 | 674 | 700 | 732 | 773 | 0.0884 | 613 | 1.124 | 98.72 | 31.38 | 1 | 0.0670 | 239 | 0.0010 | 36.61 | 7.121 | 0.1989 | 420338.0 | 283000000 | 195000000000 | 137000000000000 | 0.3984 | 0.2382 | 0.0011 | 0.0000 | 0.0011 | 0.0000 | 0.0053 | 0.0000 | 0.0083 | 0.0003 | 0.0320 | 0.0164 | 0.0531 | 0.0288 | 0.0531 | 0.0164 | 0.0753 | 0.0257 | 0.7708 | 0.9124 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0029 | 0.0003 | 0.0186 | 0.0158 | 0.0258 | 0.0270 | 0.0225 | 0.0141 | 0.0287 | 0.0217 | 0.9000 | 0.9211 | 0.0000 | 0.0000 | 0.0149 | 0.1667 | 0.0446 | 0.0833 | 0.0718 | 0.2500 | 0.0767 | 0.2500 | 0.1287 | 0.2500 | 0.0965 | 0.0000 | 0.1658 | 0.0000 | 0.4010 | 0.0000 | 0.0010 | 0.0005 | 0.0021 | 0.0124 | 0.0361 | 0.0465 | 0.0589 | 0.0780 | 0.7646 | 5 | 7 | 7 | 8 | 9 | 10 | 12 | 13 | 16 | 0.4127 | 0.30 | 1.079 | 0.7896 | 122.9 | 1790.87 | 30353.2 | 582290 | 0.5361 | 0.1291 | 0.0335 | 0.0045 | 0.0959 | 0.0139 | 0.1633 | 0.0252 | 0.2000 | 0.0536 | 0.2138 | 0.0902 | 0.1661 | 0.1532 | 0.0951 | 0.2086 | 0.0264 | 0.2648 | 0.0059 | 0.1859 | 0.0097 | 0.0003 | 0.0311 | 0.0027 | 0.0593 | 0.0058 | 0.0757 | 0.0236 | 0.0929 | 0.0587 | 0.1048 | 0.1040 | 0.1018 | 0.1321 | 0.1193 | 0.1860 | 0.4054 | 0.4869 | 0.0652 | 0.0615 | 0.0666 | 0.0608 | 0.0576 | 0.0615 | 0.0566 | 0.0660 | 0.0756 | 0.0801 | 0.0809 | 0.1008 | 0.0856 | 0.1127 | 0.1365 | 0.1579 | 0.3754 | 0.2987 | 0.0501 | 0.0714 | 0.0772 | 0.0740 | 0.0778 | 0.0730 | 0.0804 | 0.1126 | 0.3836 | |||
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 730 | 546 | 7063 | 16463 | 184.9 | 40.76 | 99.35 | 87.89 | 137 | 151 | 161 | 169 | 179 | 190 | 202 | 219 | 240 | 0.0580 | 955 | 0.941 | 64.47 | 21.02 | 1 | 0.0239 | 169 | 0.0014 | 32.05 | 6.883 | 0.2025 | 35864.6 | 7300000 | 1560000000 | 348000000000 | 0.4301 | 0.2260 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0035 | 0.0000 | 0.0175 | 0.0003 | 0.0785 | 0.0161 | 0.1523 | 0.0437 | 0.1574 | 0.0461 | 0.1936 | 0.0763 | 0.3963 | 0.8174 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0067 | 0.0003 | 0.0317 | 0.0110 | 0.0693 | 0.0226 | 0.0664 | 0.0177 | 0.0909 | 0.0300 | 0.7338 | 0.9185 | 0.0054 | 0.0134 | 0.0069 | 0.0214 | 0.0239 | 0.0456 | 0.0677 | 0.1877 | 0.1524 | 0.2091 | 0.1963 | 0.1743 | 0.1301 | 0.1072 | 0.1617 | 0.1099 | 0.2556 | 0.1314 | 0.0009 | 0.0041 | 0.0135 | 0.0340 | 0.0810 | 0.1216 | 0.1141 | 0.1377 | 0.4931 | 13 | 22 | 36 | 53 | 73 | 98 | 131 | 169 | 224 | 0.0086 | 26.48 | 6.137 | 0.3816 | 17595.6 | 4190000 | 1210000000 | 411000000000 | 0.4596 | 0.1971 | 0.0237 | 0.0019 | 0.1194 | 0.0081 | 0.2469 | 0.0504 | 0.1843 | 0.1053 | 0.1708 | 0.1723 | 0.1252 | 0.1953 | 0.0725 | 0.1462 | 0.0367 | 0.1457 | 0.0206 | 0.1747 | 0.0004 | 0.0003 | 0.0021 | 0.0017 | 0.0031 | 0.0027 | 0.0125 | 0.0104 | 0.0556 | 0.0435 | 0.0954 | 0.0686 | 0.0762 | 0.0660 | 0.1107 | 0.0934 | 0.6440 | 0.7133 | 0.0004 | 0.0007 | 0.0015 | 0.0031 | 0.0060 | 0.0094 | 0.0218 | 0.0307 | 0.0828 | 0.1016 | 0.1359 | 0.1542 | 0.1068 | 0.1143 | 0.1359 | 0.1477 | 0.5090 | 0.4384 | 0.0005 | 0.0005 | 0.0038 | 0.0189 | 0.0670 | 0.1146 | 0.0919 | 0.1238 | 0.5791 | |||
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 431 | 339 | 3943 | 10483 | 650.4 | 93.20 | 77.12 | 134.86 | 524 | 578 | 611 | 637 | 655 | 676 | 697 | 725 | 765 | 0.0630 | 660 | 1.066 | 99.30 | 32.65 | 1 | 0.0621 | 245 | 0.0013 | 29.21 | 6.926 | 0.2389 | 431670.0 | 292000000 | 201000000000 | 140000000000000 | 0.4337 | 0.2092 | 0.0006 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0043 | 0.0003 | 0.0239 | 0.0147 | 0.0347 | 0.0234 | 0.0340 | 0.0127 | 0.0534 | 0.0226 | 0.8476 | 0.9264 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0003 | 0.0148 | 0.0147 | 0.0235 | 0.0234 | 0.0179 | 0.0127 | 0.0277 | 0.0226 | 0.9140 | 0.9264 | 0.0065 | 0.0000 | 0.0065 | 0.0000 | 0.0226 | 0.0000 | 0.0355 | 0.0000 | 0.1000 | 0.0000 | 0.0871 | 0.0000 | 0.1065 | 0.0000 | 0.1290 | 0.0000 | 0.5065 | 0.0000 | 0.0000 | 0.0038 | 0.0072 | 0.0191 | 0.0401 | 0.0558 | 0.0615 | 0.0873 | 0.7252 | 6 | 8 | 9 | 11 | 14 | 22 | 53 | 125 | 238 | 0.1380 | 10.00 | 3.574 | 0.6077 | 24132.5 | 11700000 | 7110000000 | 4930000000000 | 0.4308 | 0.2239 | 0.0546 | 0.0060 | 0.1513 | 0.0313 | 0.2122 | 0.0625 | 0.1912 | 0.1159 | 0.1639 | 0.1915 | 0.1261 | 0.1935 | 0.0630 | 0.1381 | 0.0315 | 0.1190 | 0.0063 | 0.1421 | 0.0010 | 0.0000 | 0.0017 | 0.0015 | 0.0024 | 0.0033 | 0.0102 | 0.0118 | 0.0453 | 0.0386 | 0.0572 | 0.0477 | 0.0437 | 0.0443 | 0.0670 | 0.0641 | 0.7716 | 0.7887 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0020 | 0.0017 | 0.0113 | 0.0139 | 0.0577 | 0.0582 | 0.0658 | 0.0747 | 0.0516 | 0.0595 | 0.0791 | 0.0860 | 0.7313 | 0.7059 | 0.0004 | 0.0000 | 0.0015 | 0.0127 | 0.0470 | 0.0601 | 0.0548 | 0.0660 | 0.7576 | |||
SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 518 | 503 | 15648 | 56021 | 320.9 | 59.50 | 142.33 | 181.99 | 244 | 279 | 299 | 315 | 329 | 341 | 354 | 368 | 389 | 0.0239 | 1341 | 0.987 | 126.85 | 36.01 | 1 | 0.0202 | 316 | 0.0015 | 21.65 | 6.855 | 0.2488 | 106538.0 | 36300000 | 12600000000 | 4480000000000 | 0.4413 | 0.2040 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0079 | 0.0003 | 0.0295 | 0.0078 | 0.0562 | 0.0157 | 0.0615 | 0.0104 | 0.0915 | 0.0162 | 0.7503 | 0.9496 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0023 | 0.0003 | 0.0109 | 0.0075 | 0.0242 | 0.0143 | 0.0210 | 0.0081 | 0.0316 | 0.0119 | 0.9098 | 0.9580 | 0.0090 | 0.0536 | 0.0157 | 0.0179 | 0.0336 | 0.1429 | 0.0745 | 0.2143 | 0.1272 | 0.1429 | 0.1557 | 0.1607 | 0.1429 | 0.1071 | 0.1597 | 0.0357 | 0.2818 | 0.1250 | 0.0008 | 0.0025 | 0.0050 | 0.0158 | 0.0410 | 0.0684 | 0.0815 | 0.0977 | 0.6873 | 8 | 10 | 12 | 18 | 51 | 108 | 178 | 269 | 424 | 0.1076 | 16.66 | 4.969 | 0.5393 | 53375.8 | 26600000 | 15300000000 | 9680000000000 | 0.3694 | 0.2725 | 0.0166 | 0.0013 | 0.1012 | 0.0060 | 0.2168 | 0.0361 | 0.1910 | 0.0912 | 0.1770 | 0.1724 | 0.1403 | 0.2115 | 0.0824 | 0.1547 | 0.0457 | 0.1475 | 0.0291 | 0.1792 | 0.0006 | 0.0002 | 0.0006 | 0.0006 | 0.0027 | 0.0015 | 0.0085 | 0.0065 | 0.0354 | 0.0299 | 0.0682 | 0.0565 | 0.0555 | 0.0459 | 0.0719 | 0.0641 | 0.7567 | 0.7947 | 0.0005 | 0.0005 | 0.0022 | 0.0022 | 0.0040 | 0.0048 | 0.0126 | 0.0154 | 0.0463 | 0.0551 | 0.0837 | 0.0934 | 0.0695 | 0.0743 | 0.0862 | 0.0911 | 0.6950 | 0.6633 | 0.0005 | 0.0017 | 0.0041 | 0.0114 | 0.0416 | 0.0737 | 0.0613 | 0.0797 | 0.7260 | |
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 472 | 429 | 2702 | 12483 | 298.7 | 39.90 | 33.75 | 65.19 | 243 | 264 | 280 | 292 | 303 | 312 | 321 | 330 | 347 | 0.0569 | 710 | 0.587 | 156.06 | 44.65 | 2 | 0.1991 | 538 | 0.0038 | 12.01 | 5.909 | 0.3178 | 90794.9 | 28100000 | 8800000000 | 2800000000000 | 0.4181 | 0.2189 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0082 | 0.0004 | 0.0381 | 0.0222 | 0.0559 | 0.0359 | 0.0563 | 0.0200 | 0.0858 | 0.0333 | 0.7552 | 0.8882 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0045 | 0.0004 | 0.0288 | 0.0222 | 0.0365 | 0.0359 | 0.0337 | 0.0200 | 0.0483 | 0.0333 | 0.8479 | 0.8882 | 0.0064 | 0.0000 | 0.0446 | 0.0000 | 0.0318 | 0.0000 | 0.1019 | 0.0000 | 0.1338 | 0.0000 | 0.1656 | 0.0000 | 0.1529 | 0.0000 | 0.1338 | 0.0000 | 0.2293 | 0.0000 | 0.0000 | 0.0014 | 0.0095 | 0.0210 | 0.0535 | 0.0947 | 0.0947 | 0.1238 | 0.6015 | 7 | 9 | 10 | 11 | 13 | 16 | 21 | 29 | 72 | 0.2585 | 2.84 | 2.563 | 0.8124 | 5388.1 | 1890000 | 937000000 | 558000000000 | 0.6147 | 0.0974 | 0.0312 | 0.0161 | 0.0775 | 0.0194 | 0.0763 | 0.0317 | 0.1329 | 0.0506 | 0.1699 | 0.1013 | 0.1642 | 0.1079 | 0.1780 | 0.1240 | 0.1202 | 0.1614 | 0.0497 | 0.3876 | 0.0063 | 0.0091 | 0.0118 | 0.0101 | 0.0074 | 0.0133 | 0.0221 | 0.0195 | 0.0505 | 0.0405 | 0.0660 | 0.0549 | 0.0705 | 0.0613 | 0.0989 | 0.0965 | 0.6665 | 0.6947 | 0.0038 | 0.0000 | 0.0065 | 0.0043 | 0.0076 | 0.0049 | 0.0244 | 0.0232 | 0.0455 | 0.0452 | 0.0764 | 0.0757 | 0.0585 | 0.0550 | 0.0748 | 0.0794 | 0.7026 | 0.7123 | 0.0014 | 0.0082 | 0.0096 | 0.0227 | 0.0537 | 0.0719 | 0.0637 | 0.0928 | 0.6761 | |
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 895 | 609 | 4883 | 16388 | 528.4 | 82.82 | 129.28 | 239.46 | 424 | 462 | 486 | 505 | 525 | 545 | 568 | 595 | 639 | 0.0616 | 1009 | 0.725 | 104.48 | 25.55 | 1 | 0.0555 | 271 | 0.0023 | 18.30 | 6.393 | 0.2729 | 286071.0 | 158000000 | 89700000000 | 51900000000000 | 0.4173 | 0.2298 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0054 | 0.0004 | 0.0293 | 0.0147 | 0.0673 | 0.0263 | 0.0671 | 0.0165 | 0.1041 | 0.0296 | 0.7248 | 0.9125 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0004 | 0.0181 | 0.0138 | 0.0331 | 0.0232 | 0.0342 | 0.0135 | 0.0512 | 0.0220 | 0.8611 | 0.9271 | 0.0036 | 0.0000 | 0.0018 | 0.0000 | 0.0309 | 0.0882 | 0.0436 | 0.2353 | 0.1291 | 0.2941 | 0.1673 | 0.0882 | 0.0800 | 0.1765 | 0.1436 | 0.0882 | 0.4000 | 0.0294 | 0.0013 | 0.0051 | 0.0131 | 0.0300 | 0.0656 | 0.1016 | 0.0863 | 0.1121 | 0.5849 | 7 | 9 | 10 | 11 | 13 | 18 | 55 | 222 | 459 | 0.2514 | 33.66 | 3.796 | 0.6421 | 74049.5 | 59100000 | 55800000000 | 58800000000000 | 0.5654 | 0.1070 | 0.1457 | 0.0103 | 0.2870 | 0.0432 | 0.3576 | 0.2613 | 0.1369 | 0.2469 | 0.0397 | 0.2171 | 0.0221 | 0.1235 | 0.0110 | 0.0463 | 0.0000 | 0.0267 | 0.0000 | 0.0247 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0009 | 0.0004 | 0.0085 | 0.0063 | 0.0461 | 0.0469 | 0.0811 | 0.0735 | 0.0507 | 0.0480 | 0.0726 | 0.0676 | 0.7401 | 0.7571 | 0.0000 | 0.0003 | 0.0005 | 0.0000 | 0.0013 | 0.0030 | 0.0108 | 0.0120 | 0.0569 | 0.0569 | 0.0857 | 0.0867 | 0.0607 | 0.0684 | 0.0810 | 0.0878 | 0.7031 | 0.6848 | 0.0000 | 0.0000 | 0.0005 | 0.0097 | 0.0508 | 0.0832 | 0.0557 | 0.0735 | 0.7266 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1257 | 588 | 6871 | 2051 | 137.3 | 25.65 | 90.04 | 55.86 | 104 | 115 | 123 | 130 | 137 | 144 | 150 | 159 | 170 | 0.3667 | 752 | 0.924 | 92.78 | 24.76 | 1 | 0.0342 | 235 | 0.0024 | 19.20 | 6.305 | 0.2542 | 19504.3 | 2860000 | 432000000 | 67100000000 | 0.4703 | 0.1831 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0058 | 0.0004 | 0.0210 | 0.0004 | 0.0599 | 0.0142 | 0.1283 | 0.0298 | 0.1440 | 0.0322 | 0.2039 | 0.0594 | 0.4358 | 0.8634 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0026 | 0.0004 | 0.0066 | 0.0001 | 0.0250 | 0.0117 | 0.0591 | 0.0222 | 0.0521 | 0.0126 | 0.0901 | 0.0273 | 0.7638 | 0.9256 | 0.0138 | 0.0690 | 0.0324 | 0.0621 | 0.0482 | 0.1724 | 0.1455 | 0.2621 | 0.1888 | 0.1862 | 0.1642 | 0.1517 | 0.1445 | 0.0759 | 0.1259 | 0.0207 | 0.1367 | 0.0000 | 0.0006 | 0.0048 | 0.0097 | 0.0311 | 0.0829 | 0.1268 | 0.1317 | 0.1622 | 0.4503 | 25 | 40 | 54 | 69 | 83 | 97 | 113 | 133 | 160 | 0.0056 | 13.56 | 5.596 | 0.3618 | 11225.5 | 1750000 | 329000000 | 72100000000 | 0.5016 | 0.1610 | 0.0194 | 0.0010 | 0.1282 | 0.0104 | 0.2039 | 0.0604 | 0.1942 | 0.1093 | 0.1515 | 0.1894 | 0.1612 | 0.2362 | 0.0971 | 0.1592 | 0.0291 | 0.1228 | 0.0155 | 0.1113 | 0.0008 | 0.0007 | 0.0067 | 0.0028 | 0.0193 | 0.0104 | 0.0469 | 0.0291 | 0.1182 | 0.0992 | 0.1869 | 0.1881 | 0.1090 | 0.1013 | 0.1534 | 0.1367 | 0.3588 | 0.4316 | 0.0074 | 0.0125 | 0.0251 | 0.0250 | 0.0457 | 0.0813 | 0.0959 | 0.1479 | 0.1504 | 0.1583 | 0.2021 | 0.1813 | 0.1239 | 0.1458 | 0.1431 | 0.1333 | 0.2065 | 0.1146 | 0.0022 | 0.0108 | 0.0390 | 0.0683 | 0.1354 | 0.1788 | 0.1365 | 0.1560 | 0.2730 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 509 | 507 | 7824 | 25276 | 555.9 | 107.56 | 87.69 | 105.95 | 423 | 462 | 493 | 518 | 545 | 575 | 609 | 649 | 706 | 0.0436 | 1102 | 1.007 | 126.85 | 35.51 | 1 | 0.0387 | 303 | 0.0006 | 69.54 | 7.651 | 0.1417 | 320582.0 | 192000000 | 118000000000 | 75400000000000 | 0.3901 | 0.2585 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0078 | 0.0004 | 0.0495 | 0.0148 | 0.1105 | 0.0312 | 0.1156 | 0.0262 | 0.1566 | 0.0356 | 0.5585 | 0.8919 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0027 | 0.0000 | 0.0235 | 0.0112 | 0.0491 | 0.0226 | 0.0541 | 0.0132 | 0.0699 | 0.0177 | 0.7998 | 0.9352 | 0.0031 | 0.0092 | 0.0086 | 0.0323 | 0.0163 | 0.0276 | 0.0467 | 0.1198 | 0.1346 | 0.1935 | 0.1486 | 0.2166 | 0.1121 | 0.1106 | 0.1307 | 0.1290 | 0.3992 | 0.1613 | 0.0008 | 0.0025 | 0.0044 | 0.0227 | 0.0729 | 0.1111 | 0.1003 | 0.1279 | 0.5575 | 8 | 10 | 12 | 19 | 41 | 74 | 111 | 159 | 230 | 0.0557 | 17.43 | 5.062 | 0.4981 | 18913.8 | 5940000 | 2360000000 | 1110000000000 | 0.5214 | 0.1569 | 0.0217 | 0.0010 | 0.1318 | 0.0082 | 0.2484 | 0.0573 | 0.1624 | 0.1006 | 0.1628 | 0.1863 | 0.1092 | 0.2103 | 0.0691 | 0.1325 | 0.0507 | 0.1178 | 0.0438 | 0.1859 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0013 | 0.0003 | 0.0090 | 0.0059 | 0.0434 | 0.0366 | 0.0864 | 0.0707 | 0.0600 | 0.0485 | 0.0853 | 0.0637 | 0.7144 | 0.7741 | 0.0004 | 0.0001 | 0.0010 | 0.0009 | 0.0023 | 0.0038 | 0.0153 | 0.0204 | 0.0611 | 0.0695 | 0.1126 | 0.1258 | 0.0774 | 0.0886 | 0.1029 | 0.1191 | 0.6271 | 0.5718 | 0.0000 | 0.0001 | 0.0020 | 0.0125 | 0.0561 | 0.0967 | 0.0714 | 0.0968 | 0.6644 | |||
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 442 | 641 | 7990 | 25118 | 501.3 | 88.04 | 166.84 | 265.28 | 388 | 427 | 453 | 476 | 498 | 523 | 548 | 577 | 617 | 0.0471 | 1183 | 1.180 | 95.02 | 43.97 | 2 | 0.0333 | 266 | 0.0018 | 18.67 | 6.558 | 0.2470 | 259095.0 | 138000000 | 75200000000 | 42100000000000 | 0.4349 | 0.2174 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0022 | 0.0004 | 0.0081 | 0.0004 | 0.0446 | 0.0106 | 0.0956 | 0.0227 | 0.1034 | 0.0182 | 0.1448 | 0.0317 | 0.6006 | 0.9161 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0003 | 0.0024 | 0.0004 | 0.0209 | 0.0097 | 0.0427 | 0.0195 | 0.0421 | 0.0112 | 0.0628 | 0.0166 | 0.8279 | 0.9424 | 0.0064 | 0.0682 | 0.0091 | 0.0455 | 0.0320 | 0.0795 | 0.0970 | 0.1591 | 0.1473 | 0.2045 | 0.1802 | 0.1591 | 0.1180 | 0.0795 | 0.1455 | 0.0909 | 0.2644 | 0.1136 | 0.0005 | 0.0038 | 0.0054 | 0.0222 | 0.0749 | 0.1073 | 0.1055 | 0.1318 | 0.5485 | 10 | 11 | 14 | 16 | 23 | 59 | 162 | 310 | 534 | 0.1363 | 42.26 | 4.688 | 0.5832 | 98205.2 | 84400000 | 91600000000 | 119000000000000 | 0.4503 | 0.1832 | 0.0986 | 0.0041 | 0.2120 | 0.0293 | 0.2896 | 0.1678 | 0.1638 | 0.1659 | 0.1033 | 0.2136 | 0.0800 | 0.1794 | 0.0287 | 0.0875 | 0.0194 | 0.0736 | 0.0047 | 0.0788 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0006 | 0.0008 | 0.0081 | 0.0047 | 0.0452 | 0.0417 | 0.0840 | 0.0727 | 0.0594 | 0.0422 | 0.0840 | 0.0743 | 0.7185 | 0.7635 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0024 | 0.0121 | 0.0159 | 0.0604 | 0.0675 | 0.1040 | 0.1154 | 0.0752 | 0.0819 | 0.1097 | 0.1185 | 0.6378 | 0.5984 | 0.0000 | 0.0001 | 0.0012 | 0.0086 | 0.0549 | 0.0904 | 0.0693 | 0.0991 | 0.6764 | |
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 312 | 733 | 7233 | 20217 | 523.9 | 88.32 | 192.73 | 354.08 | 412 | 444 | 470 | 496 | 519 | 544 | 571 | 604 | 641 | 0.0504 | 1018 | 1.154 | 114.98 | 42.58 | 1 | 0.0408 | 295 | 0.0018 | 19.88 | 6.575 | 0.2459 | 282245.0 | 156000000 | 88600000000 | 51500000000000 | 0.4172 | 0.2311 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0003 | 0.0114 | 0.0004 | 0.0461 | 0.0113 | 0.0920 | 0.0228 | 0.1143 | 0.0150 | 0.1514 | 0.0291 | 0.5824 | 0.9210 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0046 | 0.0001 | 0.0219 | 0.0096 | 0.0442 | 0.0195 | 0.0517 | 0.0096 | 0.0720 | 0.0186 | 0.8052 | 0.9427 | 0.0032 | 0.0494 | 0.0085 | 0.0247 | 0.0481 | 0.0617 | 0.1068 | 0.2099 | 0.1474 | 0.1481 | 0.1699 | 0.1728 | 0.1453 | 0.1605 | 0.1271 | 0.1111 | 0.2436 | 0.0617 | 0.0014 | 0.0026 | 0.0072 | 0.0203 | 0.0629 | 0.1090 | 0.0973 | 0.1296 | 0.5697 | 10 | 12 | 14 | 16 | 19 | 32 | 110 | 339 | 644 | 0.1456 | 63.21 | 4.433 | 0.6015 | 162507.0 | 200000000 | 303000000000 | 525000000000000 | 0.5064 | 0.1533 | 0.1318 | 0.0049 | 0.3100 | 0.0323 | 0.3324 | 0.2391 | 0.1234 | 0.2742 | 0.0561 | 0.2167 | 0.0351 | 0.1220 | 0.0042 | 0.0617 | 0.0056 | 0.0358 | 0.0014 | 0.0133 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0005 | 0.0003 | 0.0070 | 0.0065 | 0.0491 | 0.0410 | 0.0772 | 0.0740 | 0.0498 | 0.0478 | 0.0813 | 0.0702 | 0.7351 | 0.7600 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0004 | 0.0017 | 0.0119 | 0.0114 | 0.0544 | 0.0623 | 0.0908 | 0.0925 | 0.0634 | 0.0717 | 0.0934 | 0.1071 | 0.6854 | 0.6531 | 0.0000 | 0.0002 | 0.0008 | 0.0084 | 0.0511 | 0.0851 | 0.0532 | 0.0876 | 0.7136 |