High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 811 | 224 | 3862 | 6781 | 328.4 | 152.30 | 138.02 | 238.95 | 140 | 175 | 209 | 260 | 309 | 370 | 436 | 481 | 535 | 0.0967 | 656 | 1.166 | 181.47 | 58.73 | 2 | 0.1144 | 442 | 0.0022 | 6.00 | 6.354 | 0.3863 | 131046.0 | 59300000 | 29000000000 | 15000000000000 | 0.3371 | 0.2738 | 0.0023 | 0.0005 | 0.0000 | 0.0011 | 0.0046 | 0.0043 | 0.0230 | 0.0097 | 0.0908 | 0.0500 | 0.1517 | 0.0844 | 0.1287 | 0.0580 | 0.1356 | 0.0876 | 0.4632 | 0.7045 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0048 | 0.0007 | 0.0205 | 0.0209 | 0.0301 | 0.0301 | 0.0261 | 0.0195 | 0.0305 | 0.0280 | 0.8872 | 0.9005 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0007 | 0.0052 | 0.0091 | 0.0207 | 0.0252 | 0.0342 | 0.0379 | 0.0726 | 0.0344 | 0.0654 | 0.0456 | 0.0840 | 0.8471 | 0.7168 | 0.0000 | 0.0000 | 0.0022 | 0.0039 | 0.0257 | 0.0363 | 0.0262 | 0.0312 | 0.8745 | 11 | 14 | 19 | 24 | 34 | 55 | 99 | 200 | 413 | 0.0754 | 21.49 | 4.311 | 0.6192 | 76139.6 | 68600000 | 77600000000 | 100000000000000 | 0.5118 | 0.1375 | 0.0101 | 0.0061 | 0.0553 | 0.0073 | 0.1508 | 0.0340 | 0.1508 | 0.0643 | 0.2462 | 0.1541 | 0.1683 | 0.2184 | 0.0955 | 0.1311 | 0.0628 | 0.1226 | 0.0603 | 0.2621 | 0.0000 | 0.0014 | 0.0021 | 0.0023 | 0.0057 | 0.0027 | 0.0114 | 0.0099 | 0.0532 | 0.0537 | 0.0749 | 0.0722 | 0.0583 | 0.0550 | 0.0800 | 0.0753 | 0.7145 | 0.7276 | 0.0000 | 0.0000 | 0.0039 | 0.0022 | 0.0039 | 0.0036 | 0.0123 | 0.0129 | 0.0578 | 0.0646 | 0.0884 | 0.0940 | 0.0676 | 0.0560 | 0.0799 | 0.0933 | 0.6862 | 0.6734 | 0.0006 | 0.0029 | 0.0053 | 0.0117 | 0.0516 | 0.0844 | 0.0668 | 0.0850 | 0.6917 | |||
MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 537 | 652 | 760 | 4733 | 183.3 | 48.14 | 141.14 | 250.71 | 130 | 142 | 153 | 163 | 173 | 188 | 202 | 222 | 250 | 0.1054 | 499 | 0.979 | 146.17 | 42.01 | 2 | 0.4618 | 351 | 0.0030 | 36.55 | 6.002 | 0.2222 | 35909.5 | 7530000 | 1680000000 | 400000000000 | 0.4861 | 0.1592 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0652 | 0.0044 | 0.0966 | 0.0175 | 0.1473 | 0.0773 | 0.1546 | 0.0962 | 0.1812 | 0.0845 | 0.1594 | 0.0962 | 0.1860 | 0.6239 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0297 | 0.0054 | 0.0822 | 0.0549 | 0.1154 | 0.0776 | 0.1136 | 0.0415 | 0.1416 | 0.0776 | 0.5105 | 0.7430 | 0.0000 | 0.0000 | 0.0063 | 0.0000 | 0.0253 | 0.0328 | 0.0823 | 0.2131 | 0.2595 | 0.2295 | 0.1329 | 0.2131 | 0.1139 | 0.0984 | 0.1835 | 0.1311 | 0.1962 | 0.0820 | 0.0000 | 0.0000 | 0.0150 | 0.0300 | 0.1502 | 0.1922 | 0.0991 | 0.1381 | 0.3754 | 7 | 8 | 10 | 12 | 18 | 39 | 88 | 210 | 496 | 0.1437 | 25.58 | 4.029 | 0.5929 | 82762.0 | 66600000 | 60800000000 | 59600000000000 | 0.6762 | 0.0517 | 0.0645 | 0.0022 | 0.2719 | 0.0410 | 0.3548 | 0.1339 | 0.1475 | 0.2009 | 0.0876 | 0.2203 | 0.0553 | 0.1749 | 0.0138 | 0.1058 | 0.0046 | 0.0756 | 0.0000 | 0.0454 | 0.0008 | 0.0000 | 0.0000 | 0.0007 | 0.0008 | 0.0007 | 0.0094 | 0.0131 | 0.0602 | 0.0518 | 0.1063 | 0.0801 | 0.0493 | 0.0608 | 0.1009 | 0.0849 | 0.6724 | 0.7079 | 0.0000 | 0.0000 | 0.0019 | 0.0020 | 0.0028 | 0.0020 | 0.0104 | 0.0132 | 0.0669 | 0.0731 | 0.1121 | 0.1015 | 0.0574 | 0.0701 | 0.0989 | 0.1036 | 0.6497 | 0.6345 | 0.0000 | 0.0000 | 0.0034 | 0.0086 | 0.0738 | 0.0935 | 0.0626 | 0.0995 | 0.6587 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 956 | 481 | 1986 | 9878 | 45.3 | 11.48 | 35.21 | 55.46 | 30 | 34 | 39 | 42 | 45 | 48 | 51 | 56 | 60 | 0.0765 | 756 | 0.806 | 36.77 | 10.44 | 2 | 0.0539 | 107 | 0.0083 | 3.62 | 5.056 | 0.4649 | 2186.4 | 111365 | 5950000 | 331000000 | 0.4003 | 0.2238 | 0.0019 | 0.0000 | 0.0028 | 0.0011 | 0.0131 | 0.0045 | 0.0327 | 0.0129 | 0.0515 | 0.0286 | 0.0776 | 0.0432 | 0.1132 | 0.0510 | 0.1506 | 0.0875 | 0.5566 | 0.7712 | 0.0006 | 0.0000 | 0.0006 | 0.0000 | 0.0039 | 0.0021 | 0.0129 | 0.0078 | 0.0207 | 0.0204 | 0.0311 | 0.0266 | 0.0317 | 0.0282 | 0.0498 | 0.0408 | 0.8485 | 0.8741 | 0.0084 | 0.0229 | 0.0231 | 0.0458 | 0.0231 | 0.1069 | 0.0273 | 0.0992 | 0.0588 | 0.0840 | 0.0546 | 0.0992 | 0.0777 | 0.1603 | 0.1387 | 0.1221 | 0.5882 | 0.2595 | 0.0019 | 0.0058 | 0.0145 | 0.0270 | 0.0462 | 0.0568 | 0.0751 | 0.0934 | 0.6792 | 12 | 14 | 15 | 16 | 18 | 22 | 28 | 39 | 66 | 0.3765 | 2.00 | 2.023 | 0.8544 | 4314.9 | 1380000 | 642000000 | 351000000000 | 0.5769 | 0.1123 | 0.0338 | 0.0176 | 0.0938 | 0.0290 | 0.1429 | 0.0522 | 0.1420 | 0.0746 | 0.1488 | 0.1228 | 0.1505 | 0.1485 | 0.1234 | 0.1246 | 0.1023 | 0.1456 | 0.0626 | 0.2849 | 0.0033 | 0.0112 | 0.0063 | 0.0160 | 0.0139 | 0.0227 | 0.0325 | 0.0284 | 0.0634 | 0.0516 | 0.0933 | 0.0672 | 0.0863 | 0.0700 | 0.1218 | 0.1011 | 0.5792 | 0.6317 | 0.0016 | 0.0048 | 0.0055 | 0.0068 | 0.0131 | 0.0109 | 0.0344 | 0.0505 | 0.1071 | 0.1038 | 0.1301 | 0.1633 | 0.0945 | 0.1004 | 0.1519 | 0.1346 | 0.4617 | 0.4249 | 0.0047 | 0.0060 | 0.0125 | 0.0324 | 0.0824 | 0.1100 | 0.0846 | 0.1342 | 0.5332 | |
SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 758 | 118 | 3722 | 7678 | 368.8 | 182.51 | 164.24 | 272.94 | 145 | 178 | 217 | 266 | 351 | 446 | 510 | 563 | 614 | 0.0847 | 650 | 1.108 | 87.24 | 31.58 | 2 | 0.0623 | 232 | 0.0018 | 10.54 | 6.623 | 0.3115 | 169332.0 | 88000000 | 48900000000 | 28300000000000 | 0.2899 | 0.3386 | 0.0000 | 0.0007 | 0.0000 | 0.0027 | 0.0086 | 0.0047 | 0.0310 | 0.0167 | 0.1480 | 0.0670 | 0.2220 | 0.0965 | 0.1463 | 0.0810 | 0.1911 | 0.1186 | 0.2530 | 0.6122 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0010 | 0.0020 | 0.0029 | 0.0035 | 0.0201 | 0.0203 | 0.0315 | 0.0250 | 0.0220 | 0.0238 | 0.0382 | 0.0355 | 0.8844 | 0.8892 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0066 | 0.0149 | 0.0238 | 0.0411 | 0.0416 | 0.0747 | 0.0350 | 0.0691 | 0.0430 | 0.0756 | 0.8500 | 0.7208 | 0.0000 | 0.0000 | 0.0006 | 0.0017 | 0.0251 | 0.0345 | 0.0239 | 0.0395 | 0.8747 | 12 | 17 | 22 | 28 | 43 | 72 | 114 | 240 | 499 | 0.0621 | 27.12 | 4.594 | 0.6002 | 101458.0 | 93500000 | 101000000000 | 118000000000000 | 0.3873 | 0.2579 | 0.0278 | 0.0021 | 0.0732 | 0.0103 | 0.1995 | 0.0372 | 0.1692 | 0.0702 | 0.1843 | 0.1569 | 0.1162 | 0.1610 | 0.0909 | 0.1352 | 0.0707 | 0.1197 | 0.0682 | 0.3075 | 0.0019 | 0.0000 | 0.0014 | 0.0028 | 0.0053 | 0.0035 | 0.0101 | 0.0102 | 0.0483 | 0.0501 | 0.0718 | 0.0654 | 0.0565 | 0.0556 | 0.0775 | 0.0832 | 0.7271 | 0.7292 | 0.0000 | 0.0006 | 0.0041 | 0.0006 | 0.0053 | 0.0026 | 0.0077 | 0.0057 | 0.0543 | 0.0529 | 0.0721 | 0.0861 | 0.0543 | 0.0529 | 0.0874 | 0.0848 | 0.7147 | 0.7136 | 0.0005 | 0.0027 | 0.0086 | 0.0065 | 0.0507 | 0.0706 | 0.0507 | 0.0841 | 0.7256 | |||
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 875 | 62 | 1334 | 3820 | 91.9 | 21.30 | 105.54 | 80.69 | 68 | 74 | 80 | 85 | 90 | 95 | 100 | 106 | 117 | 0.1102 | 421 | 0.866 | 95.82 | 24.17 | 1 | 0.1807 | 241 | 0.0026 | 28.10 | 6.166 | 0.2282 | 8892.5 | 911642 | 99600000 | 11700000000 | 0.4476 | 0.2105 | 0.0034 | 0.0000 | 0.0056 | 0.0000 | 0.0213 | 0.0048 | 0.0369 | 0.0081 | 0.0884 | 0.0306 | 0.1432 | 0.0564 | 0.1454 | 0.0596 | 0.1946 | 0.0854 | 0.3613 | 0.7550 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0055 | 0.0000 | 0.0157 | 0.0023 | 0.0507 | 0.0235 | 0.1005 | 0.0454 | 0.0811 | 0.0310 | 0.1180 | 0.0613 | 0.6267 | 0.8365 | 0.0419 | 0.0125 | 0.0366 | 0.0375 | 0.0628 | 0.1000 | 0.0785 | 0.1000 | 0.1937 | 0.2125 | 0.2042 | 0.1000 | 0.0628 | 0.0750 | 0.0995 | 0.1375 | 0.2199 | 0.2250 | 0.0016 | 0.0128 | 0.0096 | 0.0465 | 0.1348 | 0.1750 | 0.1236 | 0.1637 | 0.3323 | 28 | 40 | 52 | 68 | 85 | 105 | 126 | 153 | 212 | 0.0130 | 7.64 | 5.068 | 0.4624 | 17649.0 | 4150000 | 1240000000 | 442000000000 | 0.4801 | 0.1727 | 0.0158 | 0.0013 | 0.0706 | 0.0076 | 0.1364 | 0.0297 | 0.1583 | 0.0607 | 0.1754 | 0.1208 | 0.1851 | 0.1720 | 0.1218 | 0.1562 | 0.0938 | 0.1720 | 0.0426 | 0.2796 | 0.0000 | 0.0000 | 0.0021 | 0.0017 | 0.0067 | 0.0050 | 0.0249 | 0.0184 | 0.0716 | 0.0537 | 0.1095 | 0.0910 | 0.0851 | 0.0746 | 0.1183 | 0.1065 | 0.5817 | 0.6491 | 0.0036 | 0.0062 | 0.0099 | 0.0075 | 0.0172 | 0.0249 | 0.0506 | 0.0634 | 0.1112 | 0.1045 | 0.1546 | 0.1505 | 0.1103 | 0.1256 | 0.1338 | 0.1381 | 0.4087 | 0.3794 | 0.0013 | 0.0072 | 0.0118 | 0.0301 | 0.0740 | 0.1382 | 0.0950 | 0.1434 | 0.4990 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 84 | 350 | 635 | 11961 | 63.2 | 10.04 | 161.70 | 197.63 | 50 | 54 | 57 | 61 | 63 | 66 | 68 | 71 | 76 | 0.0579 | 693 | 0.875 | 142.76 | 45.97 | 2 | 0.6299 | 400 | 0.0068 | 11.22 | 5.192 | 0.3174 | 4092.7 | 271580 | 18400000 | 1280000000 | 0.4246 | 0.2192 | 0.0020 | 0.0000 | 0.0061 | 0.0016 | 0.0242 | 0.0048 | 0.0364 | 0.0111 | 0.0667 | 0.0430 | 0.1091 | 0.0685 | 0.1172 | 0.0525 | 0.1960 | 0.0812 | 0.4424 | 0.7373 | 0.0018 | 0.0000 | 0.0053 | 0.0016 | 0.0124 | 0.0047 | 0.0284 | 0.0110 | 0.0443 | 0.0379 | 0.0585 | 0.0694 | 0.0709 | 0.0394 | 0.0816 | 0.0599 | 0.6968 | 0.7760 | 0.0580 | 0.3333 | 0.0870 | 0.0000 | 0.1594 | 0.3333 | 0.0725 | 0.3333 | 0.1739 | 0.0000 | 0.0870 | 0.0000 | 0.0580 | 0.0000 | 0.1014 | 0.0000 | 0.2029 | 0.0000 | 0.0060 | 0.0030 | 0.0328 | 0.0448 | 0.0836 | 0.1045 | 0.1104 | 0.1761 | 0.4388 | 14 | 18 | 22 | 31 | 58 | 116 | 205 | 315 | 458 | 0.0352 | 28.43 | 5.403 | 0.4619 | 65200.6 | 35400000 | 22500000000 | 16100000000000 | 0.5927 | 0.1032 | 0.1018 | 0.0034 | 0.2284 | 0.0353 | 0.3243 | 0.1826 | 0.1467 | 0.1894 | 0.1089 | 0.2031 | 0.0462 | 0.1570 | 0.0249 | 0.0990 | 0.0130 | 0.0728 | 0.0059 | 0.0575 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0020 | 0.0022 | 0.0142 | 0.0124 | 0.0583 | 0.0519 | 0.0965 | 0.0944 | 0.0720 | 0.0609 | 0.0991 | 0.0924 | 0.6569 | 0.6855 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0029 | 0.0060 | 0.0195 | 0.0279 | 0.0776 | 0.0835 | 0.1193 | 0.1370 | 0.0921 | 0.0943 | 0.1271 | 0.1346 | 0.5598 | 0.5161 | 0.0002 | 0.0002 | 0.0027 | 0.0176 | 0.0677 | 0.1015 | 0.0832 | 0.1135 | 0.6134 | |
MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 469 | 438 | 2983 | 6904 | 291.5 | 155.73 | 25.80 | 36.51 | 163 | 179 | 192 | 210 | 232 | 259 | 292 | 423 | 579 | 0.1047 | 723 | 0.563 | 78.24 | 21.26 | 5 | 0.0865 | 258 | 0.0031 | 12.41 | 6.310 | 0.3653 | 109220.0 | 50500000 | 26800000000 | 15300000000000 | 0.4115 | 0.2245 | 0.0013 | 0.0000 | 0.0013 | 0.0011 | 0.0053 | 0.0049 | 0.0279 | 0.0152 | 0.0810 | 0.0455 | 0.1514 | 0.0829 | 0.1142 | 0.0650 | 0.1116 | 0.0861 | 0.5060 | 0.6994 | 0.0007 | 0.0000 | 0.0007 | 0.0008 | 0.0027 | 0.0036 | 0.0129 | 0.0101 | 0.0278 | 0.0283 | 0.0394 | 0.0449 | 0.0455 | 0.0377 | 0.0502 | 0.0494 | 0.8201 | 0.8251 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0048 | 0.0250 | 0.0353 | 0.0722 | 0.0609 | 0.0222 | 0.0304 | 0.0431 | 0.0529 | 0.8333 | 0.8157 | 0.0000 | 0.0022 | 0.0078 | 0.0100 | 0.0288 | 0.0654 | 0.0310 | 0.0488 | 0.8060 | 7 | 9 | 10 | 12 | 14 | 17 | 22 | 30 | 49 | 0.1051 | 1.66 | 3.110 | 0.7374 | 1998.1 | 320182 | 69200000 | 17600000000 | 0.5249 | 0.1326 | 0.0229 | 0.0158 | 0.0439 | 0.0273 | 0.0768 | 0.0379 | 0.1286 | 0.0532 | 0.1655 | 0.0873 | 0.1864 | 0.1237 | 0.1685 | 0.1324 | 0.1256 | 0.1938 | 0.0818 | 0.3285 | 0.0053 | 0.0100 | 0.0107 | 0.0158 | 0.0191 | 0.0197 | 0.0364 | 0.0262 | 0.0631 | 0.0494 | 0.1039 | 0.0862 | 0.0795 | 0.0733 | 0.0955 | 0.1172 | 0.5866 | 0.6021 | 0.0056 | 0.0129 | 0.0104 | 0.0069 | 0.0288 | 0.0247 | 0.0400 | 0.0366 | 0.0737 | 0.0791 | 0.1017 | 0.1098 | 0.0745 | 0.0692 | 0.1129 | 0.0930 | 0.5524 | 0.5678 | 0.0070 | 0.0152 | 0.0275 | 0.0427 | 0.0719 | 0.1029 | 0.0830 | 0.0918 | 0.5582 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 688 | 317 | 634 | 1912 | 61.1 | 11.51 | 6.65 | 2.29 | 51 | 53 | 55 | 57 | 59 | 62 | 64 | 67 | 72 | 0.1815 | 347 | 0.352 | 32.70 | 5.39 | 1 | 0.1893 | 120 | 0.1030 | 0.83 | 2.651 | 0.7146 | 3861.0 | 255798 | 18100000 | 1380000000 | 0.3514 | 0.2723 | 0.0000 | 0.0000 | 0.0055 | 0.0000 | 0.0147 | 0.0049 | 0.0257 | 0.0180 | 0.0754 | 0.0377 | 0.1471 | 0.1361 | 0.0901 | 0.0656 | 0.1746 | 0.0885 | 0.4669 | 0.6492 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0117 | 0.0016 | 0.0167 | 0.0126 | 0.0552 | 0.0379 | 0.1154 | 0.1183 | 0.0635 | 0.0473 | 0.1338 | 0.0804 | 0.6020 | 0.7019 | 0.0185 | 0.0000 | 0.0000 | 0.0000 | 0.1111 | 0.0000 | 0.0741 | 0.2500 | 0.1852 | 0.1667 | 0.1852 | 0.3333 | 0.1111 | 0.0000 | 0.0741 | 0.0833 | 0.2407 | 0.1667 | 0.0071 | 0.0179 | 0.0214 | 0.0750 | 0.1571 | 0.1607 | 0.1750 | 0.1321 | 0.2536 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 8 | 10 | 0.0192 | 7.74 | 4.309 | 0.3727 | 49.5 | 405.119 | 3603.71 | 34564.2 | 0.5192 | 0.1236 | 0.0276 | 0.0014 | 0.1166 | 0.0113 | 0.1899 | 0.0346 | 0.2067 | 0.0720 | 0.2067 | 0.1200 | 0.1322 | 0.1962 | 0.0745 | 0.2392 | 0.0397 | 0.2188 | 0.0060 | 0.1066 | 0.0107 | 0.0006 | 0.0471 | 0.0074 | 0.0661 | 0.0135 | 0.1033 | 0.0418 | 0.1281 | 0.0811 | 0.1702 | 0.1345 | 0.1860 | 0.1499 | 0.1570 | 0.2500 | 0.1314 | 0.3213 | 0.1296 | 0.2038 | 0.1640 | 0.2464 | 0.2275 | 0.2512 | 0.1772 | 0.1706 | 0.1296 | 0.0569 | 0.1032 | 0.0474 | 0.0423 | 0.0237 | 0.0265 | 0.0000 | 0.0000 | 0.0000 | 0.0322 | 0.0665 | 0.1104 | 0.1179 | 0.1533 | 0.1608 | 0.1554 | 0.1222 | 0.0815 | |
SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1199 | 461 | 4972 | 6147 | 193.3 | 101.39 | 92.03 | 198.27 | 86 | 103 | 120 | 137 | 155 | 189 | 252 | 298 | 348 | 0.1223 | 752 | 0.646 | 151.35 | 28.23 | 6 | 0.0686 | 341 | 0.0019 | 14.93 | 6.742 | 0.3352 | 47639.3 | 13900000 | 4520000000 | 1570000000000 | 0.3496 | 0.2649 | 0.0060 | 0.0004 | 0.0048 | 0.0035 | 0.0132 | 0.0052 | 0.0396 | 0.0148 | 0.1321 | 0.0461 | 0.2233 | 0.0804 | 0.1417 | 0.0722 | 0.1573 | 0.1039 | 0.2821 | 0.6735 | 0.0016 | 0.0003 | 0.0016 | 0.0017 | 0.0036 | 0.0011 | 0.0084 | 0.0058 | 0.0244 | 0.0172 | 0.0407 | 0.0302 | 0.0339 | 0.0266 | 0.0395 | 0.0388 | 0.8462 | 0.8784 | 0.0000 | 0.0008 | 0.0006 | 0.0015 | 0.0012 | 0.0061 | 0.0096 | 0.0107 | 0.0215 | 0.0313 | 0.0413 | 0.0595 | 0.0311 | 0.0489 | 0.0431 | 0.0794 | 0.8516 | 0.7618 | 0.0005 | 0.0000 | 0.0005 | 0.0046 | 0.0245 | 0.0408 | 0.0245 | 0.0362 | 0.8684 | 6 | 7 | 9 | 10 | 13 | 18 | 35 | 93 | 274 | 0.1539 | 10.11 | 3.626 | 0.6621 | 47772.6 | 36200000 | 31300000000 | 29200000000000 | 0.4667 | 0.1877 | 0.0120 | 0.0059 | 0.0518 | 0.0098 | 0.1076 | 0.0234 | 0.1992 | 0.0508 | 0.2231 | 0.1484 | 0.1673 | 0.2266 | 0.0916 | 0.1348 | 0.0598 | 0.1465 | 0.0876 | 0.2539 | 0.0007 | 0.0013 | 0.0036 | 0.0026 | 0.0051 | 0.0078 | 0.0182 | 0.0156 | 0.0547 | 0.0591 | 0.0591 | 0.0604 | 0.0562 | 0.0558 | 0.0795 | 0.0734 | 0.7228 | 0.7240 | 0.0000 | 0.0010 | 0.0063 | 0.0019 | 0.0063 | 0.0039 | 0.0116 | 0.0068 | 0.0634 | 0.0623 | 0.0598 | 0.0700 | 0.0625 | 0.0623 | 0.0938 | 0.0944 | 0.6964 | 0.6975 | 0.0008 | 0.0041 | 0.0081 | 0.0122 | 0.0575 | 0.0632 | 0.0624 | 0.0875 | 0.7042 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 193 | 840 | 364 | 9991 | 79.4 | 12.33 | 120.69 | 125.11 | 64 | 69 | 71 | 74 | 78 | 82 | 86 | 91 | 97 | 0.0656 | 655 | 0.892 | 100.23 | 30.02 | 0 | 0.7033 | 256 | 0.0097 | 8.20 | 4.818 | 0.3329 | 6458.0 | 537560 | 45800000 | 3980000000 | 0.4026 | 0.2222 | 0.0000 | 0.0000 | 0.0248 | 0.0028 | 0.0106 | 0.0055 | 0.0496 | 0.0138 | 0.1028 | 0.0608 | 0.1950 | 0.1326 | 0.1915 | 0.0856 | 0.2340 | 0.1105 | 0.1915 | 0.5884 | 0.0000 | 0.0000 | 0.0210 | 0.0027 | 0.0060 | 0.0055 | 0.0330 | 0.0137 | 0.0571 | 0.0604 | 0.1171 | 0.1319 | 0.0781 | 0.0742 | 0.1171 | 0.0934 | 0.5706 | 0.6181 | 0.0196 | 0.0000 | 0.0980 | 1.0000 | 0.0392 | 0.0000 | 0.2549 | 0.0000 | 0.1765 | 0.0000 | 0.2157 | 0.0000 | 0.0980 | 0.0000 | 0.0980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0229 | 0.0571 | 0.0400 | 0.0971 | 0.1371 | 0.1371 | 0.1771 | 0.3314 | 24 | 37 | 47 | 57 | 70 | 90 | 126 | 190 | 293 | 0.0082 | 25.67 | 5.863 | 0.4219 | 30214.6 | 11500000 | 5470000000 | 2990000000000 | 0.6670 | 0.0790 | 0.0168 | 0.0063 | 0.0841 | 0.0145 | 0.1639 | 0.0396 | 0.1869 | 0.0903 | 0.1913 | 0.1538 | 0.1665 | 0.1778 | 0.0939 | 0.1436 | 0.0709 | 0.1429 | 0.0257 | 0.2312 | 0.0013 | 0.0029 | 0.0042 | 0.0050 | 0.0088 | 0.0091 | 0.0255 | 0.0213 | 0.0682 | 0.0615 | 0.1043 | 0.0886 | 0.0823 | 0.0797 | 0.1139 | 0.1042 | 0.5915 | 0.6276 | 0.0008 | 0.0009 | 0.0049 | 0.0070 | 0.0167 | 0.0127 | 0.0318 | 0.0417 | 0.0864 | 0.0961 | 0.1262 | 0.1298 | 0.0936 | 0.1039 | 0.1259 | 0.1373 | 0.5136 | 0.4706 | 0.0016 | 0.0055 | 0.0109 | 0.0257 | 0.0792 | 0.1136 | 0.0911 | 0.1171 | 0.5553 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 56 | 911 | 384 | 7332 | 60.6 | 12.76 | 165.06 | 118.18 | 45 | 50 | 53 | 57 | 60 | 63 | 67 | 71 | 76 | 0.0614 | 450 | 0.519 | 130.54 | 26.91 | 0 | 1.0260 | 394 | 0.0099 | 9.19 | 4.826 | 0.3167 | 3828.9 | 252540 | 17400000 | 1250000000 | 0.4554 | 0.1729 | 0.0036 | 0.0000 | 0.0109 | 0.0028 | 0.0182 | 0.0055 | 0.0691 | 0.0194 | 0.1309 | 0.0720 | 0.1709 | 0.1219 | 0.1782 | 0.0914 | 0.2000 | 0.1607 | 0.2182 | 0.5263 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0093 | 0.0027 | 0.0247 | 0.0107 | 0.0957 | 0.0587 | 0.1235 | 0.1147 | 0.1173 | 0.0667 | 0.1420 | 0.1333 | 0.4877 | 0.6107 | 0.1020 | 0.0000 | 0.0612 | 0.1429 | 0.1224 | 0.0714 | 0.1020 | 0.3571 | 0.1633 | 0.2857 | 0.1837 | 0.0714 | 0.1633 | 0.0714 | 0.0612 | 0.0000 | 0.0408 | 0.0000 | 0.0053 | 0.0000 | 0.0106 | 0.0638 | 0.1596 | 0.1702 | 0.1596 | 0.1915 | 0.2394 | 18 | 37 | 71 | 117 | 158 | 195 | 232 | 274 | 329 | 0.0075 | 22.50 | 6.081 | 0.3343 | 41207.1 | 12200000 | 3970000000 | 1400000000000 | 0.4642 | 0.1955 | 0.0148 | 0.0016 | 0.1134 | 0.0089 | 0.1997 | 0.0335 | 0.1935 | 0.0895 | 0.1671 | 0.1734 | 0.1507 | 0.1952 | 0.0870 | 0.1593 | 0.0583 | 0.1613 | 0.0155 | 0.1774 | 0.0000 | 0.0000 | 0.0005 | 0.0013 | 0.0024 | 0.0011 | 0.0128 | 0.0077 | 0.0443 | 0.0302 | 0.0775 | 0.0562 | 0.0828 | 0.0523 | 0.1239 | 0.0826 | 0.6558 | 0.7687 | 0.0003 | 0.0023 | 0.0052 | 0.0099 | 0.0108 | 0.0185 | 0.0241 | 0.0468 | 0.0927 | 0.1342 | 0.1524 | 0.1640 | 0.1405 | 0.1486 | 0.1552 | 0.1721 | 0.4188 | 0.3036 | 0.0011 | 0.0025 | 0.0040 | 0.0178 | 0.0627 | 0.1136 | 0.1110 | 0.1627 | 0.5246 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 835 | 674 | 1286 | 9006 | 107.9 | 35.92 | 236.20 | 179.35 | 71 | 83 | 90 | 96 | 102 | 108 | 115 | 126 | 148 | 0.0815 | 734 | 0.834 | 60.64 | 18.97 | 2 | 0.1260 | 162 | 0.0037 | 21.25 | 5.914 | 0.2852 | 12925.5 | 1750000 | 272000000 | 48100000000 | 0.4873 | 0.1534 | 0.0027 | 0.0000 | 0.0054 | 0.0036 | 0.0308 | 0.0055 | 0.0496 | 0.0173 | 0.1300 | 0.0656 | 0.1662 | 0.0911 | 0.1421 | 0.0647 | 0.1568 | 0.1047 | 0.3164 | 0.6475 | 0.0000 | 0.0000 | 0.0031 | 0.0016 | 0.0134 | 0.0033 | 0.0237 | 0.0124 | 0.0792 | 0.0437 | 0.1132 | 0.0766 | 0.0792 | 0.0445 | 0.1091 | 0.0807 | 0.5792 | 0.7372 | 0.0088 | 0.0086 | 0.0088 | 0.0172 | 0.0265 | 0.0172 | 0.0929 | 0.0862 | 0.1106 | 0.1034 | 0.1593 | 0.1724 | 0.0885 | 0.0690 | 0.1283 | 0.1379 | 0.3761 | 0.3879 | 0.0038 | 0.0095 | 0.0302 | 0.0624 | 0.1078 | 0.1229 | 0.1096 | 0.1153 | 0.4386 | 21 | 54 | 101 | 156 | 212 | 269 | 324 | 398 | 492 | 0.0054 | 44.25 | 6.916 | 0.2857 | 87951.8 | 39600000 | 20100000000 | 11200000000000 | 0.5258 | 0.1424 | 0.0084 | 0.0013 | 0.0560 | 0.0023 | 0.1925 | 0.0179 | 0.2183 | 0.0737 | 0.2022 | 0.1661 | 0.1481 | 0.2268 | 0.0959 | 0.1657 | 0.0541 | 0.1561 | 0.0245 | 0.1900 | 0.0002 | 0.0002 | 0.0010 | 0.0009 | 0.0047 | 0.0025 | 0.0137 | 0.0101 | 0.0490 | 0.0402 | 0.0890 | 0.0809 | 0.0733 | 0.0592 | 0.1002 | 0.0870 | 0.6689 | 0.7190 | 0.0012 | 0.0019 | 0.0030 | 0.0054 | 0.0075 | 0.0103 | 0.0251 | 0.0387 | 0.0681 | 0.0831 | 0.1282 | 0.1543 | 0.1091 | 0.1091 | 0.1372 | 0.1313 | 0.5206 | 0.4659 | 0.0007 | 0.0036 | 0.0053 | 0.0177 | 0.0540 | 0.1087 | 0.0856 | 0.1201 | 0.6042 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 688 | 724 | 382 | 3170 | 111.2 | 49.61 | 43.27 | 125.08 | 45 | 55 | 71 | 91 | 111 | 133 | 151 | 163 | 177 | 0.1344 | 426 | 0.422 | 253.34 | 46.17 | 1 | 2.3037 | 880 | 0.0037 | 31.49 | 5.680 | 0.1888 | 14813.4 | 2190000 | 345000000 | 56300000000 | 0.2747 | 0.3491 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.2262 | 0.0345 | 0.3929 | 0.1379 | 0.2857 | 0.2184 | 0.0357 | 0.1494 | 0.0595 | 0.2184 | 0.0000 | 0.2356 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0072 | 0.0681 | 0.0578 | 0.0851 | 0.0866 | 0.0511 | 0.0433 | 0.0681 | 0.0650 | 0.7191 | 0.7401 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0194 | 0.0927 | 0.1553 | 0.1192 | 0.1165 | 0.0397 | 0.0971 | 0.1060 | 0.1165 | 0.6424 | 0.4854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0733 | 0.1257 | 0.0314 | 0.0733 | 0.6963 | 7 | 8 | 9 | 10 | 10 | 11 | 12 | 15 | 33 | 0.6117 | 5.34 | 1.436 | 0.8850 | 17511.8 | 11000000 | 7740000000 | 5940000000000 | 0.6927 | 0.0495 | 0.0357 | 0.0000 | 0.1429 | 0.0385 | 0.2857 | 0.0641 | 0.2143 | 0.1538 | 0.1786 | 0.2436 | 0.1429 | 0.1923 | 0.0000 | 0.1154 | 0.0000 | 0.1538 | 0.0000 | 0.0385 | 0.0032 | 0.0000 | 0.0064 | 0.0085 | 0.0064 | 0.0141 | 0.0129 | 0.0226 | 0.0386 | 0.0621 | 0.0611 | 0.0424 | 0.0675 | 0.0621 | 0.0868 | 0.1017 | 0.7170 | 0.6864 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0035 | 0.0000 | 0.0106 | 0.0181 | 0.0565 | 0.0471 | 0.0636 | 0.0870 | 0.0777 | 0.0725 | 0.0777 | 0.0725 | 0.7102 | 0.6993 | 0.0000 | 0.0000 | 0.0068 | 0.0102 | 0.0476 | 0.0612 | 0.0714 | 0.0884 | 0.7143 | |||
SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1218 | 913 | 1758 | 2499 | 60.5 | 14.09 | 168.06 | 202.27 | 37 | 49 | 56 | 60 | 64 | 66 | 69 | 72 | 76 | 0.1709 | 427 | 1.246 | 80.75 | 28.65 | 1 | 0.1115 | 196 | 0.0648 | 0.70 | 3.033 | 0.7245 | 3855.7 | 255103 | 17300000 | 1200000000 | 0.4086 | 0.2272 | 0.0020 | 0.0000 | 0.0127 | 0.0000 | 0.0402 | 0.0057 | 0.0412 | 0.0076 | 0.0794 | 0.0264 | 0.1039 | 0.0415 | 0.1265 | 0.0447 | 0.1657 | 0.0730 | 0.4284 | 0.8011 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0035 | 0.0056 | 0.0064 | 0.0062 | 0.0275 | 0.0249 | 0.0346 | 0.0386 | 0.0388 | 0.0311 | 0.0473 | 0.0398 | 0.8397 | 0.8538 | 0.0101 | 0.3889 | 0.0455 | 0.1667 | 0.0758 | 0.3889 | 0.0934 | 0.0556 | 0.1641 | 0.0000 | 0.1919 | 0.0000 | 0.1490 | 0.0000 | 0.1086 | 0.0000 | 0.1616 | 0.0000 | 0.0000 | 0.0036 | 0.0073 | 0.0255 | 0.0473 | 0.0673 | 0.1092 | 0.1583 | 0.5814 | 4 | 6 | 7 | 11 | 74 | 155 | 243 | 343 | 479 | 0.0246 | 19.24 | 4.564 | 0.3199 | 69139.4 | 35300000 | 20400000000 | 12900000000000 | 0.3902 | 0.2388 | 0.0270 | 0.0023 | 0.0991 | 0.0070 | 0.2748 | 0.0651 | 0.1802 | 0.1256 | 0.1036 | 0.1419 | 0.0856 | 0.2186 | 0.0901 | 0.1256 | 0.0676 | 0.0814 | 0.0721 | 0.2326 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0025 | 0.0102 | 0.0076 | 0.0361 | 0.0352 | 0.0981 | 0.0730 | 0.0796 | 0.0554 | 0.0907 | 0.0671 | 0.6824 | 0.7592 | 0.0000 | 0.0013 | 0.0000 | 0.0039 | 0.0012 | 0.0066 | 0.0210 | 0.0197 | 0.0723 | 0.0748 | 0.1142 | 0.1391 | 0.1037 | 0.1063 | 0.1224 | 0.1299 | 0.5653 | 0.5184 | 0.0000 | 0.0031 | 0.0031 | 0.0084 | 0.0670 | 0.0974 | 0.0827 | 0.1068 | 0.6314 | |||
MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 162 | 234 | 7241 | 33553 | 311.8 | 96.47 | 118.63 | 162.69 | 187 | 201 | 237 | 287 | 318 | 345 | 372 | 400 | 436 | 0.0350 | 1175 | 0.651 | 97.19 | 15.30 | 2 | 0.0305 | 221 | 0.0011 | 37.81 | 7.274 | 0.2128 | 106500.0 | 39100000 | 15200000000 | 6200000000000 | 0.4774 | 0.1776 | 0.0004 | 0.0012 | 0.0025 | 0.0024 | 0.0078 | 0.0057 | 0.0252 | 0.0134 | 0.0900 | 0.0431 | 0.1460 | 0.0745 | 0.1488 | 0.0709 | 0.1729 | 0.1150 | 0.4064 | 0.6737 | 0.0000 | 0.0011 | 0.0000 | 0.0020 | 0.0012 | 0.0045 | 0.0020 | 0.0085 | 0.0163 | 0.0263 | 0.0285 | 0.0387 | 0.0281 | 0.0343 | 0.0386 | 0.0461 | 0.8853 | 0.8385 | 0.0024 | 0.0155 | 0.0043 | 0.0127 | 0.0119 | 0.0325 | 0.0396 | 0.0876 | 0.0835 | 0.1441 | 0.1098 | 0.1935 | 0.1150 | 0.1483 | 0.1394 | 0.1384 | 0.4940 | 0.2274 | 0.0000 | 0.0011 | 0.0029 | 0.0135 | 0.0296 | 0.0630 | 0.0643 | 0.0849 | 0.7407 | 9 | 11 | 14 | 19 | 34 | 73 | 138 | 222 | 342 | 0.1019 | 11.63 | 4.467 | 0.5909 | 40541.7 | 20200000 | 12600000000 | 9300000000000 | 0.3536 | 0.3217 | 0.0195 | 0.0035 | 0.1006 | 0.0081 | 0.1840 | 0.0477 | 0.1733 | 0.1043 | 0.1800 | 0.1722 | 0.1418 | 0.1779 | 0.1082 | 0.1344 | 0.0594 | 0.1368 | 0.0332 | 0.2151 | 0.0001 | 0.0006 | 0.0006 | 0.0005 | 0.0020 | 0.0011 | 0.0085 | 0.0076 | 0.0341 | 0.0295 | 0.0563 | 0.0485 | 0.0428 | 0.0362 | 0.0619 | 0.0541 | 0.7937 | 0.8219 | 0.0001 | 0.0002 | 0.0013 | 0.0015 | 0.0028 | 0.0035 | 0.0110 | 0.0135 | 0.0448 | 0.0478 | 0.0745 | 0.0869 | 0.0567 | 0.0645 | 0.0842 | 0.0980 | 0.7246 | 0.6843 | 0.0002 | 0.0009 | 0.0028 | 0.0099 | 0.0385 | 0.0629 | 0.0519 | 0.0705 | 0.7623 | |
Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1142 | 857 | 7401 | 14616 | 171.0 | 66.26 | 71.29 | 133.72 | 97 | 113 | 126 | 141 | 159 | 177 | 198 | 227 | 267 | 0.0757 | 1106 | 0.455 | 200.25 | 41.00 | 7 | 0.0947 | 701 | 0.0014 | 22.02 | 6.984 | 0.2885 | 33621.9 | 7480000 | 1840000000 | 492000000000 | 0.3427 | 0.2805 | 0.0023 | 0.0008 | 0.0023 | 0.0025 | 0.0164 | 0.0059 | 0.0279 | 0.0086 | 0.0707 | 0.0301 | 0.1250 | 0.0604 | 0.1170 | 0.0539 | 0.1514 | 0.0722 | 0.4868 | 0.7658 | 0.0004 | 0.0005 | 0.0013 | 0.0012 | 0.0054 | 0.0022 | 0.0073 | 0.0043 | 0.0207 | 0.0130 | 0.0326 | 0.0254 | 0.0318 | 0.0221 | 0.0443 | 0.0300 | 0.8561 | 0.9014 | 0.0010 | 0.0000 | 0.0030 | 0.0041 | 0.0094 | 0.0058 | 0.0189 | 0.0386 | 0.0506 | 0.0641 | 0.0839 | 0.1191 | 0.0645 | 0.0994 | 0.0948 | 0.1224 | 0.6738 | 0.5464 | 0.0012 | 0.0025 | 0.0065 | 0.0109 | 0.0349 | 0.0477 | 0.0514 | 0.0767 | 0.7681 | 10 | 12 | 14 | 16 | 20 | 33 | 59 | 100 | 185 | 0.1556 | 7.37 | 3.609 | 0.6941 | 22963.2 | 18300000 | 21700000000 | 29800000000000 | 0.5623 | 0.1121 | 0.0192 | 0.0013 | 0.1028 | 0.0217 | 0.1742 | 0.0579 | 0.2030 | 0.0744 | 0.1838 | 0.1431 | 0.1324 | 0.1783 | 0.0941 | 0.1601 | 0.0662 | 0.1353 | 0.0244 | 0.2279 | 0.0000 | 0.0002 | 0.0020 | 0.0025 | 0.0051 | 0.0046 | 0.0151 | 0.0122 | 0.0523 | 0.0408 | 0.0785 | 0.0615 | 0.0621 | 0.0522 | 0.0923 | 0.0762 | 0.6926 | 0.7500 | 0.0006 | 0.0003 | 0.0012 | 0.0037 | 0.0062 | 0.0075 | 0.0211 | 0.0251 | 0.0699 | 0.0728 | 0.1077 | 0.1162 | 0.0759 | 0.0799 | 0.1107 | 0.1118 | 0.6067 | 0.5827 | 0.0003 | 0.0008 | 0.0031 | 0.0230 | 0.0637 | 0.0872 | 0.0730 | 0.0993 | 0.6497 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1243 | 854 | 722 | 7966 | 63.7 | 17.26 | 99.18 | 192.37 | 47 | 51 | 53 | 56 | 60 | 63 | 68 | 74 | 85 | 0.0734 | 585 | 0.421 | 183.11 | 37.80 | 0 | 0.8726 | 630 | 0.0093 | 10.56 | 5.018 | 0.3434 | 4360.7 | 324711 | 26600000 | 2420000000 | 0.4665 | 0.1732 | 0.0048 | 0.0000 | 0.0238 | 0.0000 | 0.0499 | 0.0060 | 0.0950 | 0.0255 | 0.1354 | 0.0510 | 0.1853 | 0.0990 | 0.1663 | 0.1049 | 0.1663 | 0.1094 | 0.1734 | 0.6042 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0128 | 0.0028 | 0.0475 | 0.0097 | 0.0786 | 0.0444 | 0.1408 | 0.0819 | 0.1261 | 0.0611 | 0.1481 | 0.0833 | 0.4388 | 0.7167 | 0.0000 | 0.0000 | 0.0317 | 0.0377 | 0.0159 | 0.0755 | 0.0952 | 0.0755 | 0.1825 | 0.3019 | 0.1825 | 0.1321 | 0.1508 | 0.0566 | 0.1508 | 0.2075 | 0.1905 | 0.1132 | 0.0036 | 0.0180 | 0.0288 | 0.0791 | 0.1259 | 0.1691 | 0.1295 | 0.1511 | 0.2950 | 10 | 12 | 14 | 15 | 17 | 19 | 31 | 113 | 371 | 0.1151 | 73.14 | 4.084 | 0.5429 | 46837.2 | 32700000 | 27500000000 | 26300000000000 | 0.6007 | 0.1115 | 0.2664 | 0.0211 | 0.4953 | 0.1607 | 0.2103 | 0.5011 | 0.0280 | 0.1882 | 0.0000 | 0.0782 | 0.0000 | 0.0338 | 0.0000 | 0.0127 | 0.0000 | 0.0042 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0022 | 0.0015 | 0.0056 | 0.0036 | 0.0185 | 0.0247 | 0.0888 | 0.0781 | 0.1355 | 0.1183 | 0.0748 | 0.0848 | 0.1231 | 0.1177 | 0.5509 | 0.5707 | 0.0006 | 0.0007 | 0.0013 | 0.0041 | 0.0083 | 0.0082 | 0.0230 | 0.0211 | 0.0856 | 0.0958 | 0.1540 | 0.1501 | 0.0818 | 0.0795 | 0.1176 | 0.1291 | 0.5278 | 0.5115 | 0.0012 | 0.0024 | 0.0054 | 0.0198 | 0.0929 | 0.1360 | 0.0827 | 0.1210 | 0.5386 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 424 | 598 | 10118 | 27401 | 44.6 | 15.32 | 9.66 | 10.14 | 26 | 30 | 34 | 39 | 43 | 46 | 51 | 58 | 68 | 0.0697 | 1910 | 0.653 | 52.00 | 10.05 | 2 | 0.0153 | 155 | 0.0320 | 0.80 | 3.734 | 0.7116 | 2220.7 | 121956 | 7260000 | 460000000 | 0.4370 | 0.1928 | 0.0033 | 0.0009 | 0.0117 | 0.0021 | 0.0212 | 0.0062 | 0.0405 | 0.0162 | 0.0660 | 0.0337 | 0.0944 | 0.0462 | 0.1215 | 0.0617 | 0.1775 | 0.0854 | 0.4639 | 0.7475 | 0.0012 | 0.0004 | 0.0041 | 0.0011 | 0.0082 | 0.0029 | 0.0150 | 0.0080 | 0.0223 | 0.0197 | 0.0297 | 0.0256 | 0.0429 | 0.0335 | 0.0634 | 0.0478 | 0.8132 | 0.8611 | 0.0054 | 0.0041 | 0.0122 | 0.0117 | 0.0168 | 0.0233 | 0.0337 | 0.0425 | 0.0471 | 0.0487 | 0.0631 | 0.0720 | 0.0608 | 0.0822 | 0.0838 | 0.0864 | 0.6771 | 0.6292 | 0.0039 | 0.0100 | 0.0142 | 0.0234 | 0.0345 | 0.0395 | 0.0542 | 0.0860 | 0.7342 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 11 | 16 | 0.0607 | 0.27 | 1.084 | 0.3393 | 196.2 | 10715.8 | 1130000 | 163000000 | 0.5653 | 0.1216 | 0.0777 | 0.0043 | 0.1202 | 0.0147 | 0.1403 | 0.0416 | 0.1602 | 0.0819 | 0.1662 | 0.1200 | 0.1599 | 0.1529 | 0.1160 | 0.1781 | 0.0486 | 0.2087 | 0.0109 | 0.1979 | 0.0433 | 0.0019 | 0.0675 | 0.0095 | 0.0728 | 0.0304 | 0.0744 | 0.0626 | 0.0830 | 0.0967 | 0.0877 | 0.1232 | 0.0996 | 0.1307 | 0.1151 | 0.1503 | 0.3566 | 0.3946 | 0.0629 | 0.0327 | 0.0480 | 0.0262 | 0.0487 | 0.0276 | 0.0411 | 0.0316 | 0.0533 | 0.0584 | 0.0696 | 0.0784 | 0.0791 | 0.0835 | 0.1064 | 0.1232 | 0.4909 | 0.5384 | 0.0684 | 0.0635 | 0.0650 | 0.0662 | 0.0726 | 0.0769 | 0.0668 | 0.0896 | 0.4311 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 923 | 124 | 725 | 2122 | 76.0 | 19.18 | 87.85 | 150.35 | 55 | 62 | 66 | 70 | 74 | 78 | 82 | 89 | 98 | 0.1555 | 330 | 1.062 | 83.67 | 27.73 | 1 | 0.3007 | 218 | 0.0059 | 12.27 | 5.382 | 0.3021 | 6143.7 | 529049 | 48700000 | 4800000000 | 0.4598 | 0.1774 | 0.0021 | 0.0000 | 0.0105 | 0.0000 | 0.0316 | 0.0062 | 0.0547 | 0.0170 | 0.1116 | 0.0602 | 0.1495 | 0.0802 | 0.1558 | 0.0725 | 0.1811 | 0.1065 | 0.3032 | 0.6574 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0100 | 0.0014 | 0.0067 | 0.0029 | 0.0585 | 0.0432 | 0.1137 | 0.0748 | 0.0870 | 0.0489 | 0.1421 | 0.0691 | 0.5803 | 0.7597 | 0.0081 | 0.0213 | 0.0488 | 0.0000 | 0.0407 | 0.0638 | 0.0894 | 0.1489 | 0.2602 | 0.2340 | 0.1057 | 0.2340 | 0.1545 | 0.0638 | 0.1463 | 0.0851 | 0.1463 | 0.1489 | 0.0000 | 0.0030 | 0.0302 | 0.0604 | 0.1329 | 0.1813 | 0.1390 | 0.1601 | 0.2931 | 14 | 17 | 20 | 25 | 38 | 53 | 73 | 106 | 191 | 0.0472 | 42.92 | 4.329 | 0.5495 | 30310.8 | 21700000 | 20800000000 | 23000000000000 | 0.5356 | 0.1304 | 0.0400 | 0.0000 | 0.1778 | 0.0200 | 0.1689 | 0.0798 | 0.2267 | 0.1098 | 0.1289 | 0.1377 | 0.1333 | 0.1896 | 0.0978 | 0.1337 | 0.0178 | 0.1018 | 0.0089 | 0.2275 | 0.0015 | 0.0000 | 0.0122 | 0.0000 | 0.0198 | 0.0141 | 0.0517 | 0.0387 | 0.0836 | 0.0810 | 0.1049 | 0.1244 | 0.1094 | 0.0845 | 0.1261 | 0.1315 | 0.4909 | 0.5258 | 0.0000 | 0.0028 | 0.0139 | 0.0057 | 0.0254 | 0.0256 | 0.0647 | 0.0427 | 0.1062 | 0.1225 | 0.1201 | 0.1595 | 0.1178 | 0.0798 | 0.1293 | 0.1681 | 0.4226 | 0.3932 | 0.0019 | 0.0130 | 0.0093 | 0.0484 | 0.1043 | 0.1229 | 0.0987 | 0.1378 | 0.4637 | |
SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 397 | 744 | 1394 | 7844 | 98.6 | 35.91 | 6.00 | 3.34 | 60 | 68 | 75 | 83 | 91 | 100 | 111 | 127 | 147 | 0.0994 | 780 | 1.009 | 108.12 | 43.32 | 4 | 0.2274 | 317 | 0.0061 | 5.91 | 5.416 | 0.4182 | 11002.2 | 1390000 | 197000000 | 30700000000 | 0.3778 | 0.2469 | 0.0000 | 0.0009 | 0.0037 | 0.0019 | 0.0074 | 0.0065 | 0.0424 | 0.0103 | 0.0996 | 0.0458 | 0.1661 | 0.0784 | 0.1661 | 0.0691 | 0.1679 | 0.0906 | 0.3469 | 0.6965 | 0.0000 | 0.0000 | 0.0023 | 0.0016 | 0.0023 | 0.0040 | 0.0193 | 0.0071 | 0.0362 | 0.0269 | 0.0657 | 0.0412 | 0.0589 | 0.0380 | 0.0668 | 0.0467 | 0.7486 | 0.8345 | 0.0000 | 0.0000 | 0.0088 | 0.0000 | 0.0088 | 0.0052 | 0.0235 | 0.0365 | 0.0587 | 0.0990 | 0.0880 | 0.1406 | 0.0762 | 0.1198 | 0.0968 | 0.1667 | 0.6393 | 0.4323 | 0.0000 | 0.0000 | 0.0106 | 0.0194 | 0.0581 | 0.0563 | 0.0722 | 0.0863 | 0.6972 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 9 | 0.2568 | 0.46 | 1.246 | 0.6521 | 47.2 | 509.972 | 7570.02 | 141592 | 0.5610 | 0.1159 | 0.0103 | 0.0017 | 0.0493 | 0.0048 | 0.1192 | 0.0132 | 0.2105 | 0.0316 | 0.2601 | 0.0696 | 0.2100 | 0.1426 | 0.1057 | 0.2424 | 0.0303 | 0.3208 | 0.0046 | 0.1733 | 0.0013 | 0.0001 | 0.0140 | 0.0004 | 0.0421 | 0.0051 | 0.1037 | 0.0149 | 0.1695 | 0.0405 | 0.2052 | 0.0848 | 0.1676 | 0.1723 | 0.1341 | 0.3107 | 0.1626 | 0.3711 | 0.1711 | 0.1604 | 0.1444 | 0.0906 | 0.0930 | 0.0767 | 0.0703 | 0.0618 | 0.0735 | 0.1056 | 0.0826 | 0.0827 | 0.0956 | 0.1215 | 0.1028 | 0.1096 | 0.1666 | 0.1912 | 0.0228 | 0.0772 | 0.1409 | 0.1642 | 0.1599 | 0.1249 | 0.0856 | 0.0848 | 0.1396 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 462 | 109 | 459 | 1169 | 64.3 | 13.23 | 8.02 | 2.47 | 48 | 52 | 57 | 61 | 64 | 67 | 71 | 74 | 79 | 0.2515 | 294 | 0.892 | 64.33 | 20.81 | 1 | 0.3791 | 174 | 0.0526 | 1.06 | 3.212 | 0.6390 | 4308.5 | 301320 | 22000000 | 1690000000 | 0.4020 | 0.2263 | 0.0000 | 0.0000 | 0.0063 | 0.0023 | 0.0094 | 0.0068 | 0.0408 | 0.0068 | 0.0940 | 0.0502 | 0.1160 | 0.1073 | 0.1473 | 0.0662 | 0.2508 | 0.0936 | 0.3354 | 0.6667 | 0.0000 | 0.0000 | 0.0026 | 0.0022 | 0.0026 | 0.0066 | 0.0238 | 0.0044 | 0.0556 | 0.0462 | 0.0635 | 0.0879 | 0.0714 | 0.0505 | 0.1111 | 0.0725 | 0.6693 | 0.7297 | 0.0678 | 0.0000 | 0.0508 | 0.0000 | 0.1356 | 0.0588 | 0.0339 | 0.1176 | 0.2034 | 0.2941 | 0.1186 | 0.1176 | 0.0678 | 0.1176 | 0.1356 | 0.2353 | 0.1864 | 0.0588 | 0.0041 | 0.0041 | 0.0245 | 0.0245 | 0.0735 | 0.0939 | 0.0898 | 0.1796 | 0.5061 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0200 | 12.70 | 4.330 | 0.3019 | 70.5 | 664.57 | 6651.59 | 70129.1 | 0.5248 | 0.1240 | 0.0136 | 0.0000 | 0.0492 | 0.0010 | 0.1121 | 0.0149 | 0.2462 | 0.0378 | 0.2394 | 0.0746 | 0.2190 | 0.1303 | 0.1002 | 0.2139 | 0.0187 | 0.2806 | 0.0017 | 0.2468 | 0.0000 | 0.0000 | 0.0099 | 0.0009 | 0.0221 | 0.0027 | 0.0585 | 0.0220 | 0.1170 | 0.0577 | 0.2064 | 0.0843 | 0.2274 | 0.1357 | 0.2506 | 0.2878 | 0.1082 | 0.4088 | 0.1199 | 0.5814 | 0.2461 | 0.2907 | 0.2366 | 0.0814 | 0.1924 | 0.0349 | 0.1293 | 0.0116 | 0.0536 | 0.0000 | 0.0158 | 0.0000 | 0.0032 | 0.0000 | 0.0032 | 0.0000 | 0.0126 | 0.0535 | 0.1258 | 0.2013 | 0.2186 | 0.1714 | 0.1336 | 0.0708 | 0.0126 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 337 | 336 | 436 | 1226 | 74.6 | 15.23 | 8.13 | 2.56 | 60 | 63 | 66 | 68 | 70 | 73 | 77 | 87 | 99 | 0.2047 | 251 | 1.186 | 32.02 | 11.05 | 1 | 0.1904 | 83 | 0.0637 | 1.09 | 3.210 | 0.6546 | 5802.3 | 471400 | 40100000 | 3560000000 | 0.4209 | 0.2111 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0159 | 0.0074 | 0.0349 | 0.0123 | 0.1111 | 0.0539 | 0.1714 | 0.1176 | 0.1270 | 0.1176 | 0.1302 | 0.1544 | 0.4095 | 0.5368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0069 | 0.0280 | 0.0115 | 0.0509 | 0.0413 | 0.0865 | 0.0894 | 0.0789 | 0.0642 | 0.0941 | 0.0917 | 0.6539 | 0.6950 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0128 | 0.1429 | 0.0641 | 0.2500 | 0.0897 | 0.2143 | 0.2821 | 0.1786 | 0.1282 | 0.1071 | 0.1154 | 0.0714 | 0.3077 | 0.0357 | 0.0134 | 0.0067 | 0.0000 | 0.0537 | 0.0872 | 0.1409 | 0.0940 | 0.1208 | 0.4832 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0165 | 10.44 | 4.481 | 0.3254 | 72.6 | 704.432 | 7374.94 | 83019.4 | 0.4958 | 0.1499 | 0.0199 | 0.0010 | 0.0634 | 0.0049 | 0.1793 | 0.0119 | 0.2500 | 0.0415 | 0.2591 | 0.0889 | 0.1612 | 0.1235 | 0.0562 | 0.2075 | 0.0091 | 0.3063 | 0.0018 | 0.2144 | 0.0011 | 0.0000 | 0.0103 | 0.0018 | 0.0411 | 0.0044 | 0.0959 | 0.0176 | 0.1610 | 0.0668 | 0.1826 | 0.0809 | 0.1724 | 0.1161 | 0.2226 | 0.2577 | 0.1130 | 0.4547 | 0.1204 | 0.2880 | 0.1821 | 0.2640 | 0.2006 | 0.1600 | 0.1728 | 0.1280 | 0.1512 | 0.0880 | 0.0895 | 0.0560 | 0.0525 | 0.0160 | 0.0278 | 0.0000 | 0.0031 | 0.0000 | 0.0118 | 0.0485 | 0.1132 | 0.1559 | 0.1529 | 0.1500 | 0.1853 | 0.1250 | 0.0574 | |
SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 451 | 11232 | 18145 | 198.9 | 80.62 | 6.13 | 2.92 | 96 | 118 | 138 | 163 | 190 | 224 | 254 | 281 | 308 | 0.0881 | 1598 | 0.402 | 135.09 | 20.03 | 6 | 0.0363 | 408 | 0.0017 | 7.54 | 6.630 | 0.3605 | 46068.3 | 11900000 | 3280000000 | 953000000000 | 0.4257 | 0.1921 | 0.0034 | 0.0015 | 0.0058 | 0.0030 | 0.0089 | 0.0074 | 0.0294 | 0.0164 | 0.0684 | 0.0406 | 0.1042 | 0.0619 | 0.1097 | 0.0584 | 0.1415 | 0.0780 | 0.5287 | 0.7328 | 0.0006 | 0.0003 | 0.0010 | 0.0001 | 0.0022 | 0.0029 | 0.0064 | 0.0067 | 0.0146 | 0.0168 | 0.0254 | 0.0283 | 0.0235 | 0.0230 | 0.0296 | 0.0320 | 0.8967 | 0.8898 | 0.0005 | 0.0025 | 0.0033 | 0.0051 | 0.0060 | 0.0132 | 0.0098 | 0.0229 | 0.0280 | 0.0467 | 0.0282 | 0.0642 | 0.0358 | 0.0778 | 0.0499 | 0.0999 | 0.8385 | 0.6677 | 0.0009 | 0.0007 | 0.0024 | 0.0073 | 0.0189 | 0.0239 | 0.0284 | 0.0375 | 0.8799 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.1305 | 0.44 | 1.002 | 0.4054 | 46.1 | 458.785 | 7687.85 | 234458 | 0.5483 | 0.1268 | 0.0123 | 0.0015 | 0.0555 | 0.0107 | 0.1399 | 0.0297 | 0.2151 | 0.0734 | 0.2476 | 0.1533 | 0.1919 | 0.2308 | 0.1031 | 0.2579 | 0.0306 | 0.1797 | 0.0042 | 0.0631 | 0.0008 | 0.0001 | 0.0083 | 0.0014 | 0.0270 | 0.0074 | 0.0633 | 0.0263 | 0.1189 | 0.0658 | 0.1643 | 0.1156 | 0.2017 | 0.2003 | 0.2201 | 0.2840 | 0.1956 | 0.2992 | 0.1197 | 0.2233 | 0.1816 | 0.2100 | 0.1733 | 0.1903 | 0.1579 | 0.1256 | 0.1231 | 0.0803 | 0.0916 | 0.0538 | 0.0625 | 0.0439 | 0.0525 | 0.0381 | 0.0379 | 0.0347 | 0.0066 | 0.0454 | 0.0962 | 0.1383 | 0.1787 | 0.1873 | 0.1512 | 0.1164 | 0.0797 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1218 | 127 | 498 | 20452 | 136.6 | 11.03 | 9.21 | 3.44 | 125 | 129 | 132 | 134 | 137 | 139 | 142 | 145 | 150 | 0.0417 | 853 | 1.250 | 19.42 | 8.06 | 3 | 0.1104 | 55 | 0.0920 | 0.84 | 2.707 | 0.6980 | 18782.2 | 2600000 | 362000000 | 50600000000 | 0.4730 | 0.1733 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0103 | 0.0080 | 0.0103 | 0.0080 | 0.0514 | 0.0502 | 0.1337 | 0.1285 | 0.0638 | 0.0582 | 0.1008 | 0.0683 | 0.6276 | 0.6787 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0103 | 0.0080 | 0.0103 | 0.0080 | 0.0513 | 0.0502 | 0.1335 | 0.1285 | 0.0637 | 0.0582 | 0.0842 | 0.0683 | 0.6448 | 0.6787 | 1.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0080 | 0.0080 | 0.0319 | 0.0956 | 0.1873 | 0.1594 | 0.1912 | 0.1753 | 0.1434 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 14 | 0.3292 | 0.40 | 0.993 | 0.6993 | 96.6 | 1114.47 | 13902.1 | 185508 | 0.4877 | 0.1649 | 0.0427 | 0.0010 | 0.1299 | 0.0068 | 0.2175 | 0.0218 | 0.2344 | 0.0618 | 0.1940 | 0.1341 | 0.1196 | 0.2265 | 0.0482 | 0.2611 | 0.0121 | 0.2035 | 0.0016 | 0.0835 | 0.0015 | 0.0001 | 0.0101 | 0.0006 | 0.0312 | 0.0040 | 0.0680 | 0.0142 | 0.1176 | 0.0364 | 0.1753 | 0.0828 | 0.2208 | 0.1592 | 0.2235 | 0.3027 | 0.1521 | 0.4001 | 0.0590 | 0.1703 | 0.1271 | 0.2470 | 0.1772 | 0.2322 | 0.1954 | 0.1620 | 0.1825 | 0.0961 | 0.1334 | 0.0570 | 0.0783 | 0.0237 | 0.0376 | 0.0074 | 0.0095 | 0.0043 | 0.0081 | 0.0349 | 0.0676 | 0.1210 | 0.1670 | 0.1995 | 0.1880 | 0.1467 | 0.0671 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 477 | 785 | 2057 | 7126 | 15.8 | 5.35 | 5.58 | 1.94 | 10 | 11 | 13 | 14 | 15 | 16 | 18 | 20 | 22 | 0.1343 | 957 | 1.077 | 39.62 | 14.00 | 0 | 0.0501 | 103 | 0.0083 | 6.76 | 5.098 | 0.3940 | 278.8 | 5536.95 | 125712 | 3300000 | 0.3803 | 0.2578 | 0.0068 | 0.0000 | 0.0241 | 0.0017 | 0.0395 | 0.0081 | 0.0656 | 0.0237 | 0.1070 | 0.0317 | 0.1466 | 0.0531 | 0.1688 | 0.1073 | 0.2054 | 0.1604 | 0.2363 | 0.6140 | 0.0048 | 0.0000 | 0.0131 | 0.0010 | 0.0220 | 0.0068 | 0.0275 | 0.0167 | 0.0440 | 0.0256 | 0.0557 | 0.0329 | 0.0688 | 0.0605 | 0.0922 | 0.0924 | 0.6717 | 0.7641 | 0.0168 | 0.0437 | 0.0216 | 0.0437 | 0.0481 | 0.0328 | 0.0793 | 0.0656 | 0.0865 | 0.1038 | 0.1346 | 0.1093 | 0.1298 | 0.0710 | 0.1394 | 0.1749 | 0.3438 | 0.3552 | 0.0178 | 0.0231 | 0.0241 | 0.0409 | 0.0409 | 0.0682 | 0.0860 | 0.1091 | 0.5897 | 3 | 4 | 5 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0254 | 8.33 | 4.093 | 0.3635 | 34.9 | 237.89 | 1743 | 13611.8 | 0.5441 | 0.1416 | 0.0029 | 0.0002 | 0.0262 | 0.0017 | 0.0867 | 0.0113 | 0.1633 | 0.0354 | 0.2318 | 0.0789 | 0.2315 | 0.1447 | 0.1584 | 0.2575 | 0.0821 | 0.2968 | 0.0170 | 0.1734 | 0.0004 | 0.0002 | 0.0045 | 0.0006 | 0.0189 | 0.0043 | 0.0680 | 0.0220 | 0.1231 | 0.0509 | 0.2194 | 0.0876 | 0.2719 | 0.1709 | 0.2172 | 0.3403 | 0.0767 | 0.3232 | 0.2384 | 0.4990 | 0.3216 | 0.3638 | 0.2659 | 0.1113 | 0.1235 | 0.0258 | 0.0369 | 0.0000 | 0.0129 | 0.0000 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0115 | 0.0662 | 0.1649 | 0.2477 | 0.2359 | 0.1587 | 0.0825 | 0.0266 | 0.0059 |