High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 365 | 353 | | 5969 | 9686 | 532.6 | 131.58 | 28.76 | 57.02 | 329 | 402 | 483 | 536 | 572 | 597 | 619 | 644 | 676 | 0.0840 | 814 | 1.039 | 109.33 | 39.70 | 3 | 0.0476 | 284 | 0.0007 | 61.44 | 7.562 | 0.1890 | 300963.0 | 177000000 | 107000000000 | 65900000000000 | 0.4153 | 0.2188 | 0.0006 | 0.0000 | 0.0018 | 0.0000 | 0.0036 | 0.0002 | 0.0109 | 0.0011 | 0.0555 | 0.0200 | 0.0772 | 0.0344 | 0.0832 | 0.0215 | 0.1212 | 0.0340 | 0.6460 | 0.8888 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0015 | 0.0011 | 0.0246 | 0.0200 | 0.0316 | 0.0336 | 0.0250 | 0.0204 | 0.0396 | 0.0310 | 0.8774 | 0.8937 | 0.0055 | 0.0000 | 0.0071 | 0.0000 | 0.0188 | 1.0000 | 0.0290 | 0.0000 | 0.0565 | 0.0000 | 0.0863 | 0.0000 | 0.0847 | 0.0000 | 0.1145 | 0.0000 | 0.5976 | 0.0000 | 0.0003 | 0.0000 | 0.0019 | 0.0047 | 0.0314 | 0.0394 | 0.0411 | 0.0607 | 0.8205 | 8 | 10 | 11 | 13 | 16 | 21 | 27 | 36 | 51 | 0.1769 | 0.75 | 1.769 | 0.6861 | 4078.2 | 2130000 | 1520000000 | 1200000000000 | 0.5279 | 0.1420 | 0.0341 | 0.0214 | 0.0384 | 0.0239 | 0.0803 | 0.0306 | 0.0852 | 0.0415 | 0.1165 | 0.0580 | 0.1541 | 0.0685 | 0.1925 | 0.0928 | 0.1996 | 0.1557 | 0.0994 | 0.5076 | 0.0086 | 0.0112 | 0.0106 | 0.0098 | 0.0185 | 0.0121 | 0.0222 | 0.0179 | 0.0376 | 0.0331 | 0.0539 | 0.0414 | 0.0587 | 0.0485 | 0.0952 | 0.0713 | 0.6946 | 0.7548 | 0.0124 | 0.0117 | 0.0133 | 0.0123 | 0.0143 | 0.0178 | 0.0219 | 0.0270 | 0.0505 | 0.0596 | 0.0657 | 0.0713 | 0.0634 | 0.0774 | 0.0991 | 0.1167 | 0.6594 | 0.6063 | 0.0141 | 0.0137 | 0.0213 | 0.0260 | 0.0416 | 0.0513 | 0.0604 | 0.0853 | 0.6863 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 927 | 522 | | 3614 | 6289 | 297.5 | 144.28 | 59.44 | 77.60 | 127 | 157 | 192 | 233 | 266 | 305 | 406 | 465 | 511 | 0.1040 | 654 | 1.229 | 109.25 | 47.52 | 2 | 0.0819 | 296 | 0.0028 | 6.07 | 6.131 | 0.4083 | 109347.0 | 45800000 | 20700000000 | 9820000000000 | 0.3640 | 0.2549 | 0.0012 | 0.0000 | 0.0012 | 0.0006 | 0.0036 | 0.0025 | 0.0324 | 0.0086 | 0.1032 | 0.0531 | 0.1429 | 0.0834 | 0.1273 | 0.0562 | 0.1020 | 0.0828 | 0.4862 | 0.7128 | 0.0005 | 0.0000 | 0.0005 | 0.0004 | 0.0005 | 0.0015 | 0.0076 | 0.0030 | 0.0219 | 0.0203 | 0.0343 | 0.0263 | 0.0281 | 0.0192 | 0.0357 | 0.0312 | 0.8710 | 0.8980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0039 | 0.0331 | 0.0347 | 0.0410 | 0.0597 | 0.0316 | 0.0414 | 0.0458 | 0.0462 | 0.8469 | 0.8141 | 0.0020 | 0.0013 | 0.0027 | 0.0054 | 0.0229 | 0.0404 | 0.0242 | 0.0310 | 0.8700 | 8 | 11 | 14 | 19 | 26 | 38 | 58 | 92 | 162 | 0.0962 | 2.42 | 3.459 | 0.6933 | 9553.8 | 2410000 | 755000000 | 271000000000 | 0.5400 | 0.1318 | 0.0018 | 0.0033 | 0.0126 | 0.0122 | 0.0650 | 0.0236 | 0.1733 | 0.0447 | 0.2365 | 0.0943 | 0.2166 | 0.1561 | 0.1480 | 0.1423 | 0.1137 | 0.1740 | 0.0325 | 0.3496 | 0.0000 | 0.0015 | 0.0005 | 0.0034 | 0.0032 | 0.0076 | 0.0142 | 0.0125 | 0.0500 | 0.0386 | 0.0866 | 0.0773 | 0.0596 | 0.0583 | 0.0830 | 0.0735 | 0.7030 | 0.7273 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0037 | 0.0064 | 0.0197 | 0.0227 | 0.0614 | 0.0716 | 0.1020 | 0.1106 | 0.0694 | 0.0738 | 0.0860 | 0.0865 | 0.6566 | 0.6270 | 0.0011 | 0.0027 | 0.0043 | 0.0160 | 0.0543 | 0.1005 | 0.0660 | 0.0787 | 0.6766 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 292 | 776 | | 6777 | 12524 | 325.6 | 51.91 | 172.85 | 222.30 | 258 | 277 | 296 | 311 | 323 | 337 | 352 | 369 | 393 | 0.0787 | 986 | 1.019 | 135.34 | 41.01 | 1 | 0.0484 | 328 | 0.0017 | 16.93 | 6.629 | 0.2646 | 108700.0 | 37200000 | 13000000000 | 4670000000000 | 0.3905 | 0.2545 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0036 | 0.0001 | 0.0131 | 0.0003 | 0.0300 | 0.0124 | 0.0571 | 0.0234 | 0.0742 | 0.0142 | 0.0991 | 0.0285 | 0.7210 | 0.9211 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0000 | 0.0071 | 0.0001 | 0.0167 | 0.0114 | 0.0295 | 0.0193 | 0.0326 | 0.0106 | 0.0443 | 0.0171 | 0.8660 | 0.9414 | 0.0057 | 0.0000 | 0.0114 | 0.0000 | 0.0341 | 0.0000 | 0.0994 | 0.0000 | 0.0994 | 0.0000 | 0.1605 | 0.0000 | 0.1179 | 0.0000 | 0.1264 | 0.0000 | 0.3452 | 0.0000 | 0.0015 | 0.0034 | 0.0073 | 0.0208 | 0.0531 | 0.0784 | 0.0815 | 0.1227 | 0.6313 | 14 | 16 | 19 | 25 | 51 | 113 | 215 | 343 | 515 | 0.0450 | 24.78 | 5.251 | 0.4914 | 79286.9 | 49200000 | 36500000000 | 31300000000000 | 0.4891 | 0.1521 | 0.0682 | 0.0006 | 0.2302 | 0.0144 | 0.3264 | 0.1428 | 0.1949 | 0.1888 | 0.1084 | 0.2199 | 0.0560 | 0.1929 | 0.0097 | 0.1180 | 0.0049 | 0.0760 | 0.0012 | 0.0466 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0015 | 0.0099 | 0.0101 | 0.0578 | 0.0482 | 0.0893 | 0.0778 | 0.0562 | 0.0523 | 0.0885 | 0.0782 | 0.6971 | 0.7317 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0023 | 0.0032 | 0.0138 | 0.0193 | 0.0706 | 0.0776 | 0.1115 | 0.1144 | 0.0701 | 0.0761 | 0.0996 | 0.1129 | 0.6310 | 0.5957 | 0.0000 | 0.0000 | 0.0012 | 0.0129 | 0.0628 | 0.1014 | 0.0584 | 0.0960 | 0.6673 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 584 | 956 | | 603 | 2463 | 406.2 | 49.35 | 106.45 | 171.74 | 341 | 360 | 374 | 391 | 405 | 421 | 434 | 449 | 475 | 0.1397 | 344 | 0.741 | 102.83 | 29.41 | 1 | 0.4809 | 290 | 0.0035 | 18.91 | 5.793 | 0.2498 | 167409.0 | 70000000 | 29700000000 | 12800000000000 | 0.3625 | 0.2807 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0037 | 0.0017 | 0.0608 | 0.0415 | 0.0958 | 0.0630 | 0.0608 | 0.0315 | 0.1105 | 0.0481 | 0.6648 | 0.8143 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0034 | 0.0017 | 0.0444 | 0.0415 | 0.0650 | 0.0630 | 0.0342 | 0.0315 | 0.0581 | 0.0481 | 0.7932 | 0.8143 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0952 | 0.0000 | 0.1190 | 0.0000 | 0.1905 | 0.0000 | 0.2381 | 0.0000 | 0.1429 | 0.0000 | 0.1190 | 0.0000 | 0.0952 | 0.0000 | 0.0000 | 0.0000 | 0.0101 | 0.0269 | 0.0842 | 0.1010 | 0.1010 | 0.1279 | 0.5488 | 8 | 10 | 11 | 13 | 15 | 30 | 107 | 188 | 310 | 0.1805 | 23.87 | 3.814 | 0.6487 | 40814.5 | 22400000 | 14400000000 | 10100000000000 | 0.5211 | 0.1245 | 0.0866 | 0.0122 | 0.0551 | 0.0528 | 0.1417 | 0.1098 | 0.2205 | 0.1138 | 0.1575 | 0.1301 | 0.1890 | 0.1707 | 0.0787 | 0.1220 | 0.0236 | 0.1260 | 0.0472 | 0.1626 | 0.0012 | 0.0000 | 0.0000 | 0.0047 | 0.0025 | 0.0070 | 0.0149 | 0.0117 | 0.0532 | 0.0493 | 0.0916 | 0.0880 | 0.0668 | 0.0563 | 0.0693 | 0.0599 | 0.7005 | 0.7230 | 0.0015 | 0.0017 | 0.0000 | 0.0033 | 0.0132 | 0.0132 | 0.0264 | 0.0281 | 0.0543 | 0.0677 | 0.1189 | 0.1254 | 0.0764 | 0.0858 | 0.0837 | 0.1073 | 0.6256 | 0.5677 | 0.0000 | 0.0013 | 0.0040 | 0.0148 | 0.0617 | 0.1074 | 0.0671 | 0.0832 | 0.6604 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 550 | 588 | | 3961 | 12702 | 362.6 | 74.74 | 145.47 | 313.98 | 267 | 301 | 325 | 344 | 362 | 380 | 400 | 423 | 452 | 0.0624 | 793 | 1.103 | 133.51 | 42.58 | 1 | 0.0836 | 331 | 0.0009 | 60.00 | 7.202 | 0.1727 | 137032.0 | 53800000 | 22000000000 | 9300000000000 | 0.4189 | 0.2240 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0191 | 0.0008 | 0.0484 | 0.0174 | 0.0949 | 0.0441 | 0.1019 | 0.0284 | 0.1484 | 0.0412 | 0.5837 | 0.8681 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0067 | 0.0008 | 0.0179 | 0.0148 | 0.0363 | 0.0309 | 0.0312 | 0.0140 | 0.0515 | 0.0197 | 0.8556 | 0.9198 | 0.0035 | 0.0177 | 0.0209 | 0.0088 | 0.0435 | 0.0796 | 0.1009 | 0.1504 | 0.1687 | 0.1770 | 0.1965 | 0.2566 | 0.1287 | 0.0442 | 0.1270 | 0.1150 | 0.2104 | 0.1504 | 0.0015 | 0.0025 | 0.0066 | 0.0207 | 0.0673 | 0.1037 | 0.0967 | 0.1463 | 0.5547 | 8 | 11 | 14 | 21 | 33 | 53 | 90 | 169 | 374 | 0.0996 | 33.81 | 4.438 | 0.6074 | 119740.0 | 178000000 | 330000000000 | 679000000000000 | 0.4919 | 0.1485 | 0.0193 | 0.0012 | 0.1035 | 0.0094 | 0.2190 | 0.0528 | 0.2154 | 0.0944 | 0.2106 | 0.1812 | 0.1408 | 0.2223 | 0.0590 | 0.1554 | 0.0217 | 0.1384 | 0.0108 | 0.1449 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0018 | 0.0021 | 0.0121 | 0.0100 | 0.0667 | 0.0554 | 0.1113 | 0.0915 | 0.0640 | 0.0610 | 0.0969 | 0.0879 | 0.6473 | 0.6909 | 0.0000 | 0.0005 | 0.0024 | 0.0064 | 0.0064 | 0.0055 | 0.0189 | 0.0132 | 0.0781 | 0.0783 | 0.1305 | 0.1429 | 0.0673 | 0.0660 | 0.0995 | 0.1051 | 0.5969 | 0.5822 | 0.0003 | 0.0007 | 0.0031 | 0.0146 | 0.0809 | 0.1122 | 0.0729 | 0.0983 | 0.6170 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 827 | 97 | | 4779 | 9869 | 431.6 | 72.01 | 52.87 | 95.06 | 321 | 371 | 401 | 423 | 444 | 465 | 484 | 498 | 512 | 0.0808 | 797 | 0.816 | 113.09 | 23.00 | 3 | 0.0515 | 246 | 0.0015 | 19.21 | 6.788 | 0.2616 | 191443.0 | 86800000 | 40100000000 | 18800000000000 | 0.4012 | 0.2344 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0037 | 0.0004 | 0.0072 | 0.0011 | 0.0289 | 0.0142 | 0.0520 | 0.0223 | 0.0494 | 0.0161 | 0.0921 | 0.0212 | 0.7664 | 0.9247 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0004 | 0.0024 | 0.0011 | 0.0169 | 0.0142 | 0.0276 | 0.0223 | 0.0203 | 0.0161 | 0.0286 | 0.0212 | 0.9034 | 0.9247 | 0.0406 | 0.0000 | 0.0406 | 0.0000 | 0.0969 | 0.0000 | 0.1031 | 0.0000 | 0.1406 | 0.0000 | 0.1875 | 0.0000 | 0.1125 | 0.0000 | 0.1188 | 0.0000 | 0.1594 | 0.0000 | 0.0026 | 0.0015 | 0.0060 | 0.0139 | 0.0285 | 0.0490 | 0.0401 | 0.0487 | 0.8098 | 5 | 6 | 8 | 9 | 10 | 13 | 28 | 75 | 177 | 0.2057 | 10.66 | 3.527 | 0.6733 | 11831.5 | 4010000 | 1640000000 | 755000000000 | 0.4322 | 0.1951 | 0.0842 | 0.0023 | 0.1811 | 0.0240 | 0.2704 | 0.1244 | 0.1505 | 0.1210 | 0.1505 | 0.2237 | 0.1148 | 0.1872 | 0.0332 | 0.1016 | 0.0128 | 0.1062 | 0.0026 | 0.1096 | 0.0000 | 0.0000 | 0.0020 | 0.0007 | 0.0032 | 0.0060 | 0.0134 | 0.0112 | 0.0512 | 0.0417 | 0.0721 | 0.0684 | 0.0473 | 0.0407 | 0.0776 | 0.0691 | 0.7333 | 0.7622 | 0.0005 | 0.0005 | 0.0014 | 0.0015 | 0.0061 | 0.0051 | 0.0182 | 0.0243 | 0.0634 | 0.0694 | 0.0895 | 0.0861 | 0.0541 | 0.0597 | 0.0848 | 0.0891 | 0.6822 | 0.6643 | 0.0009 | 0.0017 | 0.0021 | 0.0167 | 0.0541 | 0.0824 | 0.0558 | 0.0815 | 0.7048 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 376 | 670 | | 11475 | 30585 | 465.6 | 100.42 | 131.66 | 237.18 | 350 | 378 | 401 | 424 | 447 | 473 | 505 | 551 | 622 | 0.0430 | 1316 | 1.157 | 137.30 | 49.41 | 1 | 0.0297 | 341 | 0.0015 | 21.13 | 6.886 | 0.2666 | 226895.0 | 116000000 | 61700000000 | 34300000000000 | 0.4225 | 0.2239 | 0.0007 | 0.0000 | 0.0015 | 0.0002 | 0.0037 | 0.0005 | 0.0127 | 0.0019 | 0.0414 | 0.0147 | 0.0727 | 0.0296 | 0.0882 | 0.0265 | 0.1258 | 0.0409 | 0.6532 | 0.8857 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0014 | 0.0000 | 0.0059 | 0.0002 | 0.0182 | 0.0083 | 0.0338 | 0.0145 | 0.0420 | 0.0091 | 0.0610 | 0.0147 | 0.8365 | 0.9533 | 0.0028 | 0.0121 | 0.0080 | 0.0151 | 0.0099 | 0.0302 | 0.0274 | 0.0710 | 0.0690 | 0.1480 | 0.0922 | 0.1631 | 0.0813 | 0.1329 | 0.1068 | 0.1647 | 0.6026 | 0.2628 | 0.0008 | 0.0026 | 0.0051 | 0.0240 | 0.0431 | 0.0825 | 0.0785 | 0.0990 | 0.6644 | 5 | 6 | 8 | 9 | 12 | 26 | 86 | 218 | 471 | 0.1403 | 63.23 | 4.504 | 0.5576 | 73585.6 | 57500000 | 53700000000 | 56800000000000 | 0.4673 | 0.1625 | 0.0887 | 0.0045 | 0.2607 | 0.0499 | 0.2554 | 0.2123 | 0.1210 | 0.1544 | 0.1082 | 0.1653 | 0.0736 | 0.1423 | 0.0413 | 0.0927 | 0.0316 | 0.0855 | 0.0195 | 0.0931 | 0.0001 | 0.0000 | 0.0005 | 0.0003 | 0.0014 | 0.0003 | 0.0066 | 0.0066 | 0.0477 | 0.0419 | 0.0761 | 0.0690 | 0.0508 | 0.0460 | 0.0878 | 0.0763 | 0.7290 | 0.7595 | 0.0001 | 0.0001 | 0.0001 | 0.0010 | 0.0019 | 0.0016 | 0.0087 | 0.0121 | 0.0598 | 0.0631 | 0.0938 | 0.0985 | 0.0624 | 0.0744 | 0.1049 | 0.1107 | 0.6681 | 0.6384 | 0.0003 | 0.0003 | 0.0015 | 0.0081 | 0.0555 | 0.0813 | 0.0601 | 0.0971 | 0.6958 | ||
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 609 | 251 | | 8474 | 32235 | 492.3 | 132.68 | 164.80 | 304.29 | 304 | 403 | 447 | 478 | 505 | 531 | 562 | 596 | 642 | 0.0423 | 1362 | 0.553 | 103.04 | 22.02 | 6 | 0.0340 | 288 | 0.0004 | 114.84 | 8.011 | 0.1304 | 259967.0 | 144000000 | 83000000000 | 49400000000000 | 0.3722 | 0.2591 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0037 | 0.0003 | 0.0143 | 0.0023 | 0.0499 | 0.0166 | 0.1100 | 0.0376 | 0.1112 | 0.0351 | 0.1452 | 0.0452 | 0.5648 | 0.8630 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0001 | 0.0025 | 0.0009 | 0.0146 | 0.0117 | 0.0325 | 0.0201 | 0.0307 | 0.0127 | 0.0470 | 0.0181 | 0.8723 | 0.9363 | 0.0022 | 0.0048 | 0.0077 | 0.0143 | 0.0132 | 0.0286 | 0.0548 | 0.0835 | 0.1064 | 0.2124 | 0.1656 | 0.1742 | 0.1162 | 0.1074 | 0.1436 | 0.1480 | 0.3904 | 0.2267 | 0.0004 | 0.0024 | 0.0034 | 0.0209 | 0.0482 | 0.0869 | 0.0897 | 0.1054 | 0.6428 | 11 | 14 | 16 | 19 | 25 | 41 | 97 | 243 | 543 | 0.1744 | 25.68 | 4.127 | 0.6433 | 119746.0 | 132000000 | 179000000000 | 274000000000000 | 0.3012 | 0.3397 | 0.0899 | 0.0040 | 0.2395 | 0.0218 | 0.2653 | 0.1374 | 0.1444 | 0.1732 | 0.1091 | 0.1910 | 0.0818 | 0.1739 | 0.0413 | 0.1102 | 0.0177 | 0.0848 | 0.0111 | 0.1039 | 0.0005 | 0.0004 | 0.0016 | 0.0005 | 0.0018 | 0.0022 | 0.0158 | 0.0127 | 0.0501 | 0.0477 | 0.0704 | 0.0633 | 0.0461 | 0.0432 | 0.0696 | 0.0655 | 0.7443 | 0.7646 | 0.0003 | 0.0003 | 0.0003 | 0.0026 | 0.0043 | 0.0048 | 0.0182 | 0.0201 | 0.0595 | 0.0574 | 0.0778 | 0.0868 | 0.0553 | 0.0575 | 0.0768 | 0.0805 | 0.7076 | 0.6901 | 0.0004 | 0.0001 | 0.0031 | 0.0149 | 0.0534 | 0.0785 | 0.0435 | 0.0762 | 0.7299 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 969 | 728 | | 16378 | 49009 | 195.5 | 37.68 | 203.96 | 331.62 | 151 | 169 | 180 | 189 | 198 | 206 | 215 | 226 | 241 | 0.0278 | 1362 | 1.188 | 93.09 | 34.48 | 1 | 0.0143 | 235 | 0.0032 | 12.80 | 6.161 | 0.3225 | 39638.5 | 8270000 | 1770000000 | 387000000000 | 0.4222 | 0.2262 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0037 | 0.0000 | 0.0129 | 0.0003 | 0.0346 | 0.0080 | 0.0661 | 0.0181 | 0.0824 | 0.0160 | 0.1152 | 0.0268 | 0.6836 | 0.9309 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0036 | 0.0001 | 0.0120 | 0.0068 | 0.0260 | 0.0139 | 0.0283 | 0.0069 | 0.0418 | 0.0107 | 0.8870 | 0.9616 | 0.0089 | 0.0576 | 0.0166 | 0.0995 | 0.0426 | 0.1047 | 0.0736 | 0.1780 | 0.1192 | 0.1937 | 0.1473 | 0.1675 | 0.1256 | 0.0733 | 0.1456 | 0.0890 | 0.3206 | 0.0366 | 0.0012 | 0.0027 | 0.0072 | 0.0202 | 0.0501 | 0.0834 | 0.0821 | 0.1197 | 0.6333 | 7 | 8 | 10 | 12 | 17 | 54 | 192 | 390 | 701 | 0.1432 | 35.53 | 4.788 | 0.5519 | 151568.0 | 149000000 | 169000000000 | 211000000000000 | 0.4292 | 0.2197 | 0.0529 | 0.0035 | 0.2034 | 0.0131 | 0.2775 | 0.1127 | 0.1544 | 0.1604 | 0.1262 | 0.2014 | 0.0909 | 0.1979 | 0.0516 | 0.1081 | 0.0322 | 0.1003 | 0.0110 | 0.1027 | 0.0001 | 0.0001 | 0.0003 | 0.0001 | 0.0010 | 0.0003 | 0.0081 | 0.0057 | 0.0395 | 0.0371 | 0.0691 | 0.0641 | 0.0487 | 0.0414 | 0.0700 | 0.0648 | 0.7633 | 0.7864 | 0.0004 | 0.0003 | 0.0011 | 0.0011 | 0.0028 | 0.0036 | 0.0129 | 0.0138 | 0.0452 | 0.0466 | 0.0753 | 0.0825 | 0.0565 | 0.0561 | 0.0729 | 0.0789 | 0.7329 | 0.7170 | 0.0001 | 0.0013 | 0.0022 | 0.0102 | 0.0423 | 0.0730 | 0.0512 | 0.0723 | 0.7473 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 137 | 324 | | 5641 | 20747 | 281.5 | 64.71 | 102.70 | 136.65 | 202 | 225 | 243 | 262 | 277 | 293 | 311 | 335 | 366 | 0.0556 | 1153 | 0.979 | 115.25 | 26.87 | 1 | 0.0456 | 257 | 0.0006 | 71.66 | 7.549 | 0.1440 | 83449.7 | 26000000 | 8510000000 | 2920000000000 | 0.4017 | 0.2486 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0038 | 0.0000 | 0.0232 | 0.0027 | 0.0713 | 0.0198 | 0.1447 | 0.0392 | 0.1676 | 0.0472 | 0.1783 | 0.0677 | 0.4103 | 0.8235 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0000 | 0.0102 | 0.0011 | 0.0291 | 0.0141 | 0.0555 | 0.0255 | 0.0700 | 0.0224 | 0.0851 | 0.0349 | 0.7483 | 0.9020 | 0.0009 | 0.0074 | 0.0085 | 0.0257 | 0.0180 | 0.0662 | 0.0722 | 0.1029 | 0.1472 | 0.1838 | 0.1918 | 0.1618 | 0.1149 | 0.1360 | 0.1434 | 0.1140 | 0.3029 | 0.2022 | 0.0023 | 0.0015 | 0.0072 | 0.0281 | 0.0795 | 0.1228 | 0.1049 | 0.1327 | 0.5209 | 11 | 14 | 17 | 23 | 35 | 63 | 115 | 185 | 286 | 0.0458 | 14.71 | 4.863 | 0.5260 | 29220.6 | 12900000 | 7580000000 | 5510000000000 | 0.5276 | 0.1342 | 0.0999 | 0.0045 | 0.3282 | 0.0294 | 0.3393 | 0.1714 | 0.1201 | 0.2314 | 0.0597 | 0.2369 | 0.0285 | 0.1756 | 0.0132 | 0.0762 | 0.0090 | 0.0458 | 0.0021 | 0.0287 | 0.0003 | 0.0002 | 0.0004 | 0.0007 | 0.0014 | 0.0014 | 0.0118 | 0.0117 | 0.0724 | 0.0573 | 0.1165 | 0.1003 | 0.0799 | 0.0698 | 0.1094 | 0.0976 | 0.6080 | 0.6610 | 0.0005 | 0.0006 | 0.0012 | 0.0025 | 0.0034 | 0.0047 | 0.0207 | 0.0211 | 0.0878 | 0.0967 | 0.1435 | 0.1663 | 0.0940 | 0.0978 | 0.1317 | 0.1352 | 0.5172 | 0.4752 | 0.0002 | 0.0006 | 0.0024 | 0.0191 | 0.0743 | 0.1338 | 0.0863 | 0.1178 | 0.5656 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 409 | 890 | | 816 | 11183 | 89.7 | 9.29 | 105.45 | 153.75 | 78 | 81 | 84 | 87 | 90 | 92 | 95 | 98 | 101 | 0.0640 | 716 | 0.688 | 118.34 | 30.02 | 4 | 0.4142 | 338 | 0.0250 | 2.26 | 3.936 | 0.5414 | 8132.4 | 745123 | 69000000 | 6450000000 | 0.4240 | 0.2141 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0038 | 0.0012 | 0.0166 | 0.0086 | 0.0422 | 0.0319 | 0.0575 | 0.0564 | 0.0665 | 0.0380 | 0.1151 | 0.0576 | 0.6982 | 0.8064 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0012 | 0.0137 | 0.0086 | 0.0373 | 0.0319 | 0.0460 | 0.0564 | 0.0522 | 0.0380 | 0.0646 | 0.0576 | 0.7826 | 0.8064 | 0.1304 | 0.0000 | 0.0870 | 0.0000 | 0.0870 | 0.0000 | 0.2174 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.0870 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0048 | 0.0096 | 0.0265 | 0.0265 | 0.0964 | 0.1084 | 0.1084 | 0.1880 | 0.4313 | 12 | 15 | 19 | 25 | 36 | 56 | 93 | 175 | 308 | 0.0583 | 19.57 | 4.627 | 0.5749 | 34757.8 | 18600000 | 13100000000 | 11000000000000 | 0.5602 | 0.1268 | 0.0620 | 0.0049 | 0.1860 | 0.0220 | 0.2709 | 0.1170 | 0.1685 | 0.1506 | 0.1119 | 0.1935 | 0.0876 | 0.1911 | 0.0539 | 0.1066 | 0.0270 | 0.0980 | 0.0323 | 0.1164 | 0.0006 | 0.0010 | 0.0025 | 0.0017 | 0.0048 | 0.0048 | 0.0202 | 0.0167 | 0.0663 | 0.0628 | 0.1003 | 0.0944 | 0.0621 | 0.0604 | 0.1056 | 0.0980 | 0.6376 | 0.6603 | 0.0011 | 0.0004 | 0.0011 | 0.0008 | 0.0032 | 0.0054 | 0.0231 | 0.0233 | 0.0774 | 0.0848 | 0.1214 | 0.1431 | 0.0781 | 0.0809 | 0.1256 | 0.1268 | 0.5692 | 0.5344 | 0.0010 | 0.0016 | 0.0058 | 0.0214 | 0.0672 | 0.1140 | 0.0643 | 0.1191 | 0.6056 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1125 | 641 | | 11752 | 25342 | 232.5 | 61.19 | 170.59 | 255.96 | 162 | 186 | 201 | 215 | 228 | 242 | 257 | 278 | 310 | 0.0510 | 1293 | 1.092 | 30.46 | 9.43 | 3 | 0.0062 | 73 | 0.0008 | 52.10 | 7.510 | 0.1713 | 57786.2 | 15300000 | 4280000000 | 1270000000000 | 0.4266 | 0.2087 | 0.0003 | 0.0000 | 0.0011 | 0.0002 | 0.0038 | 0.0004 | 0.0137 | 0.0016 | 0.0570 | 0.0194 | 0.1221 | 0.0376 | 0.1242 | 0.0374 | 0.1725 | 0.0532 | 0.5053 | 0.8503 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0015 | 0.0000 | 0.0056 | 0.0005 | 0.0238 | 0.0113 | 0.0480 | 0.0188 | 0.0513 | 0.0158 | 0.0752 | 0.0235 | 0.7940 | 0.9300 | 0.0039 | 0.0023 | 0.0117 | 0.0081 | 0.0174 | 0.0151 | 0.0516 | 0.0755 | 0.0951 | 0.1231 | 0.1428 | 0.1649 | 0.0872 | 0.1115 | 0.1228 | 0.1161 | 0.4674 | 0.3833 | 0.0018 | 0.0029 | 0.0093 | 0.0250 | 0.0622 | 0.0988 | 0.0949 | 0.1131 | 0.5921 | 9 | 12 | 17 | 32 | 58 | 95 | 152 | 272 | 534 | 0.0689 | 34.29 | 5.267 | 0.5297 | 94612.1 | 77200000 | 75700000000 | 83200000000000 | 0.3585 | 0.3278 | 0.0395 | 0.0012 | 0.1512 | 0.0108 | 0.2256 | 0.0794 | 0.1461 | 0.1072 | 0.1502 | 0.1684 | 0.1169 | 0.1823 | 0.0707 | 0.1281 | 0.0608 | 0.1168 | 0.0390 | 0.2056 | 0.0006 | 0.0003 | 0.0021 | 0.0014 | 0.0038 | 0.0026 | 0.0153 | 0.0136 | 0.0581 | 0.0480 | 0.0869 | 0.0812 | 0.0666 | 0.0586 | 0.0861 | 0.0828 | 0.6805 | 0.7116 | 0.0002 | 0.0007 | 0.0019 | 0.0034 | 0.0056 | 0.0081 | 0.0251 | 0.0236 | 0.0640 | 0.0649 | 0.0941 | 0.0908 | 0.0674 | 0.0685 | 0.0855 | 0.0777 | 0.6563 | 0.6622 | 0.0007 | 0.0013 | 0.0062 | 0.0194 | 0.0623 | 0.0938 | 0.0645 | 0.0859 | 0.6660 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 260 | 906 | | 6741 | 5810 | 457.5 | 85.03 | 189.24 | 346.87 | 354 | 397 | 434 | 457 | 471 | 484 | 497 | 515 | 542 | 0.1139 | 662 | 0.726 | 107.34 | 27.78 | 4 | 0.0481 | 324 | 0.0013 | 28.66 | 7.062 | 0.2336 | 216541.0 | 105000000 | 52100000000 | 26300000000000 | 0.4404 | 0.2127 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0038 | 0.0000 | 0.0072 | 0.0011 | 0.0244 | 0.0142 | 0.0415 | 0.0371 | 0.0385 | 0.0169 | 0.0651 | 0.0290 | 0.8182 | 0.9017 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0026 | 0.0000 | 0.0044 | 0.0005 | 0.0175 | 0.0138 | 0.0303 | 0.0338 | 0.0218 | 0.0135 | 0.0322 | 0.0208 | 0.8903 | 0.9176 | 0.0174 | 0.0000 | 0.0209 | 0.0000 | 0.0192 | 0.0000 | 0.0314 | 0.0000 | 0.0401 | 0.0000 | 0.0627 | 0.0000 | 0.0592 | 0.0000 | 0.0941 | 0.0000 | 0.6551 | 0.0000 | 0.0007 | 0.0045 | 0.0057 | 0.0172 | 0.0314 | 0.0528 | 0.0617 | 0.0889 | 0.7372 | 15 | 17 | 18 | 21 | 27 | 55 | 114 | 280 | 602 | 0.2435 | 18.42 | 3.549 | 0.6966 | 156109.0 | 197000000 | 310000000000 | 567000000000000 | 0.6374 | 0.0658 | 0.0763 | 0.0000 | 0.1968 | 0.0329 | 0.2129 | 0.1024 | 0.1566 | 0.1225 | 0.1406 | 0.1846 | 0.1245 | 0.1554 | 0.0482 | 0.1280 | 0.0361 | 0.1188 | 0.0080 | 0.1554 | 0.0013 | 0.0000 | 0.0019 | 0.0006 | 0.0039 | 0.0023 | 0.0142 | 0.0138 | 0.0685 | 0.0619 | 0.0931 | 0.0865 | 0.0672 | 0.0613 | 0.1002 | 0.0980 | 0.6496 | 0.6756 | 0.0008 | 0.0000 | 0.0031 | 0.0025 | 0.0046 | 0.0067 | 0.0208 | 0.0200 | 0.0701 | 0.0835 | 0.1017 | 0.0943 | 0.0770 | 0.0760 | 0.1063 | 0.1077 | 0.6156 | 0.6093 | 0.0000 | 0.0014 | 0.0043 | 0.0157 | 0.0686 | 0.1029 | 0.0657 | 0.1064 | 0.6350 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1104 | 606 | | 7792 | 17317 | 455.1 | 84.64 | 91.04 | 159.85 | 350 | 380 | 405 | 428 | 449 | 472 | 497 | 528 | 568 | 0.0587 | 1017 | 0.843 | 136.49 | 39.96 | 1 | 0.0508 | 396 | 0.0009 | 41.02 | 7.256 | 0.1774 | 214248.0 | 104000000 | 52400000000 | 27200000000000 | 0.4390 | 0.2040 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0136 | 0.0005 | 0.0498 | 0.0107 | 0.1097 | 0.0237 | 0.1108 | 0.0193 | 0.1486 | 0.0344 | 0.5627 | 0.9113 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0024 | 0.0000 | 0.0058 | 0.0004 | 0.0229 | 0.0095 | 0.0478 | 0.0189 | 0.0484 | 0.0112 | 0.0635 | 0.0227 | 0.8089 | 0.9373 | 0.0050 | 0.0153 | 0.0059 | 0.0153 | 0.0243 | 0.0458 | 0.0703 | 0.1756 | 0.1456 | 0.1221 | 0.1816 | 0.1603 | 0.1364 | 0.0916 | 0.1356 | 0.1069 | 0.2954 | 0.2672 | 0.0019 | 0.0038 | 0.0059 | 0.0261 | 0.0676 | 0.1051 | 0.0997 | 0.1070 | 0.5829 | 5 | 6 | 7 | 9 | 11 | 25 | 76 | 148 | 295 | 0.1599 | 22.17 | 4.036 | 0.5973 | 33837.1 | 18800000 | 12800000000 | 9900000000000 | 0.6360 | 0.0673 | 0.0357 | 0.0021 | 0.1417 | 0.0167 | 0.2200 | 0.0889 | 0.1536 | 0.1271 | 0.1497 | 0.1836 | 0.1249 | 0.1857 | 0.0694 | 0.1130 | 0.0565 | 0.1130 | 0.0486 | 0.1700 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0006 | 0.0003 | 0.0113 | 0.0062 | 0.0430 | 0.0382 | 0.0708 | 0.0689 | 0.0549 | 0.0430 | 0.0815 | 0.0753 | 0.7371 | 0.7679 | 0.0002 | 0.0000 | 0.0005 | 0.0010 | 0.0049 | 0.0052 | 0.0117 | 0.0160 | 0.0608 | 0.0640 | 0.0963 | 0.1006 | 0.0629 | 0.0694 | 0.0974 | 0.1091 | 0.6653 | 0.6349 | 0.0002 | 0.0006 | 0.0023 | 0.0121 | 0.0489 | 0.0886 | 0.0606 | 0.0917 | 0.6949 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 547 | 289 | | 11285 | 27072 | 244.5 | 58.73 | 197.38 | 232.26 | 172 | 193 | 209 | 224 | 239 | 255 | 274 | 296 | 325 | 0.0436 | 1181 | 1.186 | 113.74 | 45.89 | 1 | 0.0262 | 296 | 0.0006 | 59.04 | 7.598 | 0.1608 | 63242.6 | 17200000 | 4920000000 | 1470000000000 | 0.4595 | 0.1977 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0003 | 0.0222 | 0.0030 | 0.0838 | 0.0183 | 0.1665 | 0.0428 | 0.1519 | 0.0447 | 0.1695 | 0.0687 | 0.4015 | 0.8221 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0009 | 0.0000 | 0.0056 | 0.0015 | 0.0329 | 0.0117 | 0.0689 | 0.0232 | 0.0624 | 0.0202 | 0.0836 | 0.0302 | 0.7454 | 0.9132 | 0.0042 | 0.0118 | 0.0042 | 0.0251 | 0.0161 | 0.0340 | 0.0589 | 0.0991 | 0.1158 | 0.1731 | 0.1866 | 0.1864 | 0.1001 | 0.1080 | 0.1387 | 0.1391 | 0.3753 | 0.2234 | 0.0010 | 0.0019 | 0.0079 | 0.0250 | 0.0784 | 0.1238 | 0.0992 | 0.1291 | 0.5338 | 14 | 18 | 26 | 48 | 94 | 162 | 255 | 375 | 541 | 0.0240 | 59.33 | 6.100 | 0.4045 | 92900.8 | 59800000 | 46700000000 | 42500000000000 | 0.3821 | 0.2440 | 0.0415 | 0.0013 | 0.1747 | 0.0119 | 0.3178 | 0.1184 | 0.1407 | 0.1403 | 0.1199 | 0.1896 | 0.0884 | 0.1946 | 0.0465 | 0.1232 | 0.0336 | 0.1013 | 0.0369 | 0.1196 | 0.0001 | 0.0002 | 0.0000 | 0.0003 | 0.0009 | 0.0010 | 0.0080 | 0.0057 | 0.0480 | 0.0394 | 0.0973 | 0.0776 | 0.0603 | 0.0509 | 0.0905 | 0.0756 | 0.6949 | 0.7492 | 0.0002 | 0.0004 | 0.0020 | 0.0014 | 0.0027 | 0.0026 | 0.0159 | 0.0171 | 0.0664 | 0.0775 | 0.1207 | 0.1335 | 0.0813 | 0.0857 | 0.1106 | 0.1232 | 0.6001 | 0.5585 | 0.0001 | 0.0006 | 0.0019 | 0.0122 | 0.0586 | 0.1142 | 0.0705 | 0.1007 | 0.6412 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 472 | 365 | | 10152 | 16333 | 306.6 | 57.54 | 224.30 | 196.37 | 237 | 256 | 271 | 285 | 301 | 317 | 336 | 357 | 386 | 0.0678 | 1107 | 0.822 | 136.62 | 44.05 | 1 | 0.0396 | 402 | 0.0006 | 77.66 | 7.651 | 0.1416 | 97320.9 | 31900000 | 10800000000 | 3780000000000 | 0.4559 | 0.2016 | 0.0007 | 0.0000 | 0.0006 | 0.0000 | 0.0038 | 0.0001 | 0.0147 | 0.0006 | 0.0559 | 0.0105 | 0.1218 | 0.0272 | 0.1337 | 0.0260 | 0.1584 | 0.0428 | 0.5103 | 0.8928 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0036 | 0.0001 | 0.0257 | 0.0079 | 0.0578 | 0.0184 | 0.0582 | 0.0109 | 0.0841 | 0.0197 | 0.7693 | 0.9430 | 0.0025 | 0.0159 | 0.0101 | 0.0518 | 0.0297 | 0.0876 | 0.0802 | 0.2072 | 0.1723 | 0.1952 | 0.1799 | 0.1474 | 0.1187 | 0.1036 | 0.1503 | 0.0558 | 0.2563 | 0.1355 | 0.0008 | 0.0025 | 0.0127 | 0.0317 | 0.0909 | 0.1254 | 0.1094 | 0.1379 | 0.4885 | 22 | 46 | 83 | 125 | 173 | 229 | 295 | 376 | 500 | 0.0068 | 69.26 | 6.886 | 0.2834 | 88869.9 | 46400000 | 29000000000 | 20500000000000 | 0.5451 | 0.1262 | 0.0275 | 0.0020 | 0.1405 | 0.0066 | 0.2540 | 0.0553 | 0.1753 | 0.1106 | 0.1531 | 0.1890 | 0.1086 | 0.2034 | 0.0715 | 0.1379 | 0.0376 | 0.1361 | 0.0319 | 0.1591 | 0.0004 | 0.0006 | 0.0004 | 0.0007 | 0.0035 | 0.0023 | 0.0163 | 0.0094 | 0.0680 | 0.0540 | 0.1119 | 0.0867 | 0.0864 | 0.0698 | 0.1192 | 0.1056 | 0.5940 | 0.6708 | 0.0002 | 0.0013 | 0.0020 | 0.0036 | 0.0087 | 0.0107 | 0.0296 | 0.0330 | 0.1018 | 0.1162 | 0.1498 | 0.1759 | 0.1073 | 0.1119 | 0.1433 | 0.1478 | 0.4572 | 0.3996 | 0.0004 | 0.0016 | 0.0045 | 0.0181 | 0.0879 | 0.1310 | 0.0994 | 0.1385 | 0.5186 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1218 | 150 | | 8328 | 20825 | 278.7 | 60.80 | 290.87 | 439.80 | 204 | 240 | 258 | 272 | 285 | 298 | 311 | 327 | 347 | 0.0520 | 1082 | 0.814 | 131.22 | 25.94 | 2 | 0.0359 | 299 | 0.0015 | 25.68 | 6.861 | 0.2311 | 81369.2 | 24600000 | 7610000000 | 2410000000000 | 0.4056 | 0.2353 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0106 | 0.0006 | 0.0413 | 0.0112 | 0.0811 | 0.0241 | 0.0864 | 0.0135 | 0.1377 | 0.0258 | 0.6381 | 0.9247 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0001 | 0.0143 | 0.0100 | 0.0289 | 0.0185 | 0.0247 | 0.0084 | 0.0466 | 0.0146 | 0.8830 | 0.9483 | 0.0055 | 0.0364 | 0.0234 | 0.0182 | 0.0343 | 0.0455 | 0.0810 | 0.1273 | 0.1262 | 0.1364 | 0.1752 | 0.3091 | 0.1371 | 0.0909 | 0.1269 | 0.0727 | 0.2905 | 0.1636 | 0.0015 | 0.0033 | 0.0074 | 0.0220 | 0.0435 | 0.0863 | 0.0844 | 0.1177 | 0.6340 | 7 | 10 | 13 | 17 | 28 | 115 | 308 | 594 | 1020 | 0.0848 | 69.35 | 5.353 | 0.4886 | 278017.0 | 336000000 | 456000000000 | 669000000000000 | 0.5138 | 0.1645 | 0.0468 | 0.0052 | 0.1680 | 0.0170 | 0.2305 | 0.1168 | 0.1460 | 0.1394 | 0.1433 | 0.1748 | 0.1148 | 0.1667 | 0.0661 | 0.1295 | 0.0487 | 0.1130 | 0.0358 | 0.1375 | 0.0003 | 0.0003 | 0.0000 | 0.0003 | 0.0009 | 0.0009 | 0.0078 | 0.0073 | 0.0402 | 0.0330 | 0.0717 | 0.0659 | 0.0532 | 0.0476 | 0.0763 | 0.0708 | 0.7497 | 0.7740 | 0.0002 | 0.0011 | 0.0003 | 0.0020 | 0.0034 | 0.0050 | 0.0145 | 0.0131 | 0.0489 | 0.0487 | 0.0799 | 0.0830 | 0.0597 | 0.0625 | 0.0824 | 0.0882 | 0.7106 | 0.6963 | 0.0002 | 0.0002 | 0.0019 | 0.0108 | 0.0438 | 0.0821 | 0.0547 | 0.0780 | 0.7283 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 767 | 375 | | 10994 | 36702 | 317.2 | 66.33 | 88.78 | 117.60 | 238 | 259 | 276 | 292 | 309 | 327 | 346 | 373 | 410 | 0.0385 | 1412 | 0.777 | 113.02 | 23.02 | 1 | 0.0226 | 249 | 0.0006 | 70.27 | 7.726 | 0.1479 | 104984.0 | 36300000 | 13000000000 | 4880000000000 | 0.4228 | 0.2250 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0001 | 0.0125 | 0.0008 | 0.0612 | 0.0134 | 0.1259 | 0.0305 | 0.1295 | 0.0324 | 0.1666 | 0.0567 | 0.4994 | 0.8660 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0062 | 0.0003 | 0.0265 | 0.0088 | 0.0510 | 0.0177 | 0.0541 | 0.0124 | 0.0766 | 0.0239 | 0.7828 | 0.9370 | 0.0031 | 0.0102 | 0.0078 | 0.0225 | 0.0225 | 0.0758 | 0.0628 | 0.1250 | 0.1313 | 0.1557 | 0.1763 | 0.1475 | 0.1104 | 0.1025 | 0.1423 | 0.1270 | 0.3433 | 0.2336 | 0.0010 | 0.0030 | 0.0062 | 0.0294 | 0.0726 | 0.1184 | 0.1031 | 0.1345 | 0.5318 | 10 | 12 | 14 | 19 | 32 | 55 | 97 | 156 | 255 | 0.0788 | 13.52 | 4.639 | 0.5538 | 21712.5 | 8010000 | 3800000000 | 2180000000000 | 0.4103 | 0.2154 | 0.0637 | 0.0009 | 0.2390 | 0.0098 | 0.3525 | 0.1068 | 0.1643 | 0.1924 | 0.0959 | 0.2534 | 0.0480 | 0.2004 | 0.0216 | 0.1040 | 0.0113 | 0.0742 | 0.0037 | 0.0580 | 0.0002 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0012 | 0.0109 | 0.0097 | 0.0639 | 0.0507 | 0.0964 | 0.0843 | 0.0715 | 0.0616 | 0.1087 | 0.0931 | 0.6473 | 0.6989 | 0.0002 | 0.0004 | 0.0011 | 0.0016 | 0.0034 | 0.0043 | 0.0175 | 0.0189 | 0.0814 | 0.0927 | 0.1222 | 0.1338 | 0.0853 | 0.0887 | 0.1273 | 0.1253 | 0.5616 | 0.5343 | 0.0001 | 0.0004 | 0.0016 | 0.0110 | 0.0724 | 0.1147 | 0.0774 | 0.1169 | 0.6055 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 945 | 791 | | 7136 | 8653 | 396.4 | 68.86 | 331.09 | 487.17 | 292 | 338 | 365 | 386 | 406 | 423 | 439 | 454 | 478 | 0.0953 | 825 | 1.046 | 109.66 | 38.48 | 6 | 0.0419 | 299 | 0.0024 | 9.08 | 6.362 | 0.3660 | 161888.0 | 67800000 | 29000000000 | 12700000000000 | 0.4181 | 0.2153 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0038 | 0.0000 | 0.0079 | 0.0011 | 0.0218 | 0.0106 | 0.0533 | 0.0271 | 0.0385 | 0.0132 | 0.0585 | 0.0186 | 0.8142 | 0.9294 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0011 | 0.0113 | 0.0105 | 0.0289 | 0.0260 | 0.0141 | 0.0119 | 0.0204 | 0.0173 | 0.9222 | 0.9333 | 0.0066 | 0.0000 | 0.0066 | 0.0000 | 0.0263 | 0.0000 | 0.0447 | 0.0000 | 0.1092 | 0.0000 | 0.1184 | 0.0000 | 0.1158 | 0.0000 | 0.1382 | 0.0000 | 0.4342 | 0.0000 | 0.0005 | 0.0015 | 0.0051 | 0.0101 | 0.0281 | 0.0398 | 0.0367 | 0.0529 | 0.8252 | 10 | 12 | 15 | 26 | 85 | 211 | 381 | 631 | 998 | 0.1055 | 26.80 | 5.014 | 0.5502 | 346927.0 | 541000000 | 1110000000000 | 2.77E+15 | 0.4761 | 0.1685 | 0.0161 | 0.0031 | 0.0966 | 0.0086 | 0.1804 | 0.0350 | 0.1739 | 0.0871 | 0.1643 | 0.1540 | 0.1433 | 0.1882 | 0.0934 | 0.1407 | 0.0805 | 0.1198 | 0.0515 | 0.2636 | 0.0003 | 0.0008 | 0.0006 | 0.0014 | 0.0025 | 0.0017 | 0.0063 | 0.0068 | 0.0348 | 0.0256 | 0.0659 | 0.0501 | 0.0446 | 0.0400 | 0.0681 | 0.0535 | 0.7768 | 0.8202 | 0.0000 | 0.0004 | 0.0004 | 0.0018 | 0.0039 | 0.0049 | 0.0102 | 0.0123 | 0.0481 | 0.0511 | 0.0777 | 0.0886 | 0.0560 | 0.0675 | 0.0765 | 0.0825 | 0.7272 | 0.6909 | 0.0000 | 0.0004 | 0.0036 | 0.0093 | 0.0411 | 0.0750 | 0.0496 | 0.0650 | 0.7562 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 998 | 485 | | 4473 | 15868 | 223.3 | 42.57 | 170.54 | 190.66 | 167 | 185 | 199 | 211 | 221 | 232 | 244 | 259 | 279 | 0.0531 | 843 | 0.739 | 107.82 | 35.01 | 1 | 0.0722 | 323 | 0.0012 | 31.42 | 6.899 | 0.2014 | 51676.7 | 12400000 | 3060000000 | 781000000000 | 0.4192 | 0.2236 | 0.0016 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0000 | 0.0147 | 0.0009 | 0.0482 | 0.0156 | 0.1042 | 0.0328 | 0.1130 | 0.0248 | 0.1586 | 0.0425 | 0.5557 | 0.8834 | 0.0013 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0048 | 0.0002 | 0.0213 | 0.0134 | 0.0435 | 0.0239 | 0.0437 | 0.0125 | 0.0680 | 0.0215 | 0.8155 | 0.9284 | 0.0073 | 0.0174 | 0.0132 | 0.0174 | 0.0323 | 0.0348 | 0.0852 | 0.1826 | 0.1160 | 0.1739 | 0.1880 | 0.2000 | 0.1483 | 0.1217 | 0.1219 | 0.1043 | 0.2878 | 0.1478 | 0.0018 | 0.0050 | 0.0055 | 0.0315 | 0.0721 | 0.1132 | 0.1178 | 0.1251 | 0.5279 | 12 | 17 | 28 | 49 | 86 | 143 | 221 | 333 | 461 | 0.0266 | 31.54 | 5.838 | 0.4485 | 65434.3 | 33400000 | 20100000000 | 13900000000000 | 0.5142 | 0.1765 | 0.0522 | 0.0024 | 0.1949 | 0.0152 | 0.2023 | 0.0988 | 0.1266 | 0.1475 | 0.1199 | 0.1915 | 0.1098 | 0.1664 | 0.0831 | 0.1072 | 0.0522 | 0.0954 | 0.0589 | 0.1756 | 0.0003 | 0.0004 | 0.0003 | 0.0008 | 0.0018 | 0.0008 | 0.0091 | 0.0077 | 0.0519 | 0.0426 | 0.0874 | 0.0779 | 0.0733 | 0.0632 | 0.1020 | 0.0877 | 0.6738 | 0.7190 | 0.0004 | 0.0004 | 0.0014 | 0.0034 | 0.0038 | 0.0054 | 0.0148 | 0.0199 | 0.0648 | 0.0719 | 0.1143 | 0.1171 | 0.0843 | 0.0862 | 0.1204 | 0.1209 | 0.5958 | 0.5749 | 0.0003 | 0.0012 | 0.0037 | 0.0126 | 0.0592 | 0.0980 | 0.0826 | 0.1114 | 0.6309 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 842 | 577 | | 8312 | 37624 | 297.8 | 91.57 | 178.27 | 259.96 | 160 | 206 | 245 | 278 | 307 | 333 | 362 | 387 | 411 | 0.0319 | 1200 | 0.839 | 102.04 | 23.02 | 1 | 0.0298 | 248 | 0.0012 | 10.68 | 6.901 | 0.3043 | 97039.9 | 33700000 | 12200000000 | 4600000000000 | 0.3862 | 0.2351 | 0.0012 | 0.0000 | 0.0021 | 0.0005 | 0.0039 | 0.0017 | 0.0170 | 0.0054 | 0.0499 | 0.0240 | 0.0762 | 0.0398 | 0.0810 | 0.0408 | 0.1043 | 0.0580 | 0.6643 | 0.8299 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0003 | 0.0001 | 0.0033 | 0.0020 | 0.0152 | 0.0128 | 0.0244 | 0.0202 | 0.0207 | 0.0155 | 0.0268 | 0.0229 | 0.9088 | 0.9263 | 0.0015 | 0.0106 | 0.0030 | 0.0151 | 0.0049 | 0.0408 | 0.0118 | 0.0711 | 0.0323 | 0.0968 | 0.0433 | 0.1452 | 0.0429 | 0.0953 | 0.0771 | 0.1589 | 0.7831 | 0.3661 | 0.0009 | 0.0016 | 0.0029 | 0.0068 | 0.0201 | 0.0316 | 0.0289 | 0.0382 | 0.8689 | 8 | 10 | 12 | 16 | 37 | 86 | 182 | 353 | 594 | 0.1248 | 17.36 | 4.816 | 0.6022 | 99357.5 | 73300000 | 62400000000 | 58600000000000 | 0.4227 | 0.2238 | 0.0264 | 0.0016 | 0.1059 | 0.0050 | 0.1959 | 0.0402 | 0.1696 | 0.0969 | 0.1979 | 0.1765 | 0.1462 | 0.2004 | 0.0726 | 0.1356 | 0.0497 | 0.1265 | 0.0358 | 0.2174 | 0.0000 | 0.0002 | 0.0005 | 0.0004 | 0.0018 | 0.0011 | 0.0067 | 0.0062 | 0.0389 | 0.0323 | 0.0555 | 0.0517 | 0.0427 | 0.0407 | 0.0604 | 0.0544 | 0.7937 | 0.8129 | 0.0002 | 0.0007 | 0.0011 | 0.0010 | 0.0034 | 0.0033 | 0.0119 | 0.0117 | 0.0387 | 0.0431 | 0.0656 | 0.0654 | 0.0477 | 0.0528 | 0.0658 | 0.0696 | 0.7657 | 0.7523 | 0.0000 | 0.0006 | 0.0016 | 0.0095 | 0.0399 | 0.0611 | 0.0434 | 0.0640 | 0.7799 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1060 | 148 | | 9173 | 22344 | 294.9 | 54.87 | 142.27 | 167.42 | 227 | 246 | 262 | 276 | 290 | 304 | 321 | 343 | 371 | 0.0689 | 1540 | 0.872 | 128.71 | 44.38 | 1 | 0.0395 | 362 | 0.0007 | 53.70 | 7.461 | 0.1589 | 89976.7 | 28400000 | 9240000000 | 3100000000000 | 0.4189 | 0.2273 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0039 | 0.0000 | 0.0119 | 0.0010 | 0.0544 | 0.0105 | 0.1011 | 0.0239 | 0.1296 | 0.0218 | 0.1648 | 0.0345 | 0.5330 | 0.9084 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0059 | 0.0002 | 0.0246 | 0.0088 | 0.0420 | 0.0180 | 0.0587 | 0.0104 | 0.0811 | 0.0154 | 0.7860 | 0.9472 | 0.0035 | 0.0359 | 0.0110 | 0.0256 | 0.0311 | 0.0769 | 0.0876 | 0.1487 | 0.1090 | 0.1436 | 0.1739 | 0.1641 | 0.1256 | 0.1128 | 0.1387 | 0.1231 | 0.3195 | 0.1692 | 0.0012 | 0.0047 | 0.0077 | 0.0323 | 0.0798 | 0.1131 | 0.0949 | 0.1254 | 0.5411 | 14 | 17 | 22 | 39 | 72 | 114 | 176 | 260 | 379 | 0.0282 | 29.29 | 5.688 | 0.4480 | 48267.7 | 23800000 | 15100000000 | 12000000000000 | 0.5526 | 0.1273 | 0.0495 | 0.0023 | 0.1676 | 0.0182 | 0.2382 | 0.0872 | 0.1820 | 0.1262 | 0.1201 | 0.1819 | 0.1042 | 0.1777 | 0.0735 | 0.1315 | 0.0360 | 0.1131 | 0.0288 | 0.1618 | 0.0010 | 0.0004 | 0.0013 | 0.0008 | 0.0025 | 0.0027 | 0.0122 | 0.0114 | 0.0574 | 0.0459 | 0.1001 | 0.0810 | 0.0689 | 0.0643 | 0.0971 | 0.0872 | 0.6595 | 0.7063 | 0.0003 | 0.0003 | 0.0007 | 0.0013 | 0.0044 | 0.0053 | 0.0173 | 0.0217 | 0.0820 | 0.0881 | 0.1194 | 0.1360 | 0.0834 | 0.0891 | 0.1164 | 0.1154 | 0.5761 | 0.5428 | 0.0005 | 0.0013 | 0.0029 | 0.0153 | 0.0705 | 0.1085 | 0.0767 | 0.1091 | 0.6152 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 157 | 329 | | 1738 | 4874 | 829.9 | 218.86 | 12.72 | 6.17 | 545 | 606 | 672 | 746 | 818 | 889 | 972 | 1058 | 1144 | 0.0903 | 440 | 1.050 | 47.54 | 16.03 | 1 | 0.0702 | 122 | 0.0011 | 32.34 | 6.913 | 0.1942 | 736559.0 | 692000000 | 681000000000 | 695000000000000 | 0.3830 | 0.2470 | 0.0000 | 0.0006 | 0.0000 | 0.0006 | 0.0039 | 0.0013 | 0.0209 | 0.0071 | 0.0706 | 0.0292 | 0.1033 | 0.0565 | 0.0928 | 0.0435 | 0.1294 | 0.0617 | 0.5791 | 0.7994 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0057 | 0.0024 | 0.0283 | 0.0209 | 0.0404 | 0.0435 | 0.0323 | 0.0215 | 0.0477 | 0.0316 | 0.8448 | 0.8802 | 0.0021 | 0.0217 | 0.0042 | 0.0145 | 0.0064 | 0.0145 | 0.0169 | 0.0725 | 0.0360 | 0.0870 | 0.0636 | 0.0797 | 0.0487 | 0.1377 | 0.0805 | 0.2101 | 0.7415 | 0.3623 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0311 | 0.0587 | 0.0335 | 0.0467 | 0.8228 | 7 | 8 | 10 | 11 | 12 | 13 | 15 | 16 | 19 | 0.0061 | 22.32 | 5.502 | 0.2607 | 199.8 | 4679.1 | 209109 | 15400000 | 0.5319 | 0.1291 | 0.0389 | 0.0014 | 0.1029 | 0.0079 | 0.1520 | 0.0200 | 0.1856 | 0.0485 | 0.2128 | 0.0891 | 0.1653 | 0.1213 | 0.0976 | 0.2022 | 0.0368 | 0.2799 | 0.0080 | 0.2298 | 0.0185 | 0.0007 | 0.0406 | 0.0045 | 0.0564 | 0.0121 | 0.0554 | 0.0289 | 0.0716 | 0.0535 | 0.0848 | 0.0705 | 0.1039 | 0.1025 | 0.1729 | 0.1735 | 0.3959 | 0.5540 | 0.0744 | 0.1222 | 0.0666 | 0.1109 | 0.1055 | 0.1598 | 0.1038 | 0.1297 | 0.1176 | 0.1297 | 0.1272 | 0.1034 | 0.1375 | 0.1034 | 0.1280 | 0.0658 | 0.1393 | 0.0752 | 0.0362 | 0.0460 | 0.0596 | 0.0732 | 0.0779 | 0.1009 | 0.1300 | 0.2155 | 0.2606 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 819 | 741 | | 5979 | 6896 | 220.8 | 55.20 | 179.58 | 138.54 | 160 | 176 | 189 | 201 | 212 | 224 | 239 | 259 | 290 | 0.1115 | 769 | 1.055 | 105.12 | 32.02 | 1 | 0.0418 | 250 | 0.0010 | 54.65 | 7.224 | 0.1685 | 51796.9 | 13000000 | 3490000000 | 1010000000000 | 0.4435 | 0.2077 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0040 | 0.0000 | 0.0187 | 0.0015 | 0.0749 | 0.0195 | 0.1570 | 0.0462 | 0.1484 | 0.0436 | 0.1840 | 0.0676 | 0.4128 | 0.8214 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0000 | 0.0059 | 0.0002 | 0.0381 | 0.0134 | 0.0733 | 0.0232 | 0.0677 | 0.0209 | 0.1008 | 0.0375 | 0.7133 | 0.9047 | 0.0048 | 0.0024 | 0.0107 | 0.0000 | 0.0213 | 0.0095 | 0.0804 | 0.0735 | 0.1231 | 0.1659 | 0.1841 | 0.2109 | 0.0940 | 0.0948 | 0.1260 | 0.1469 | 0.3556 | 0.2962 | 0.0016 | 0.0020 | 0.0102 | 0.0317 | 0.0939 | 0.1412 | 0.1146 | 0.1451 | 0.4597 | 35 | 59 | 83 | 111 | 142 | 182 | 230 | 292 | 373 | 0.0020 | 58.17 | 6.937 | 0.2558 | 51437.9 | 19300000 | 8700000000 | 4480000000000 | 0.5354 | 0.1275 | 0.0234 | 0.0012 | 0.1292 | 0.0079 | 0.2559 | 0.0540 | 0.1882 | 0.1092 | 0.1683 | 0.1926 | 0.1110 | 0.1934 | 0.0642 | 0.1357 | 0.0399 | 0.1274 | 0.0199 | 0.1785 | 0.0000 | 0.0000 | 0.0012 | 0.0007 | 0.0041 | 0.0040 | 0.0199 | 0.0119 | 0.0809 | 0.0632 | 0.1232 | 0.1038 | 0.0870 | 0.0722 | 0.1300 | 0.1109 | 0.5537 | 0.6333 | 0.0022 | 0.0006 | 0.0018 | 0.0033 | 0.0106 | 0.0155 | 0.0343 | 0.0472 | 0.1004 | 0.1210 | 0.1612 | 0.1805 | 0.1233 | 0.1260 | 0.1440 | 0.1460 | 0.4223 | 0.3598 | 0.0018 | 0.0029 | 0.0068 | 0.0310 | 0.0863 | 0.1320 | 0.1059 | 0.1469 | 0.4864 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 895 | 228 | | 1426 | 7457 | 297.1 | 74.97 | 7.35 | 3.00 | 208 | 227 | 244 | 263 | 287 | 309 | 333 | 361 | 411 | 0.0758 | 565 | 1.060 | 52.39 | 17.09 | 1 | 0.0912 | 130 | 0.0050 | 5.81 | 5.550 | 0.3967 | 93879.8 | 31500000 | 11200000000 | 4160000000000 | 0.4025 | 0.2290 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0040 | 0.0008 | 0.0374 | 0.0038 | 0.0602 | 0.0369 | 0.0989 | 0.0638 | 0.0936 | 0.0430 | 0.1283 | 0.0692 | 0.5775 | 0.7809 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0171 | 0.0007 | 0.0286 | 0.0288 | 0.0390 | 0.0400 | 0.0448 | 0.0204 | 0.0524 | 0.0435 | 0.8171 | 0.8667 | 0.0000 | 0.0000 | 0.0066 | 0.0161 | 0.0166 | 0.0000 | 0.0364 | 0.0242 | 0.0530 | 0.1694 | 0.0629 | 0.1774 | 0.0927 | 0.0806 | 0.1060 | 0.2339 | 0.6258 | 0.2984 | 0.0016 | 0.0016 | 0.0109 | 0.0203 | 0.0422 | 0.0422 | 0.0703 | 0.0766 | 0.7344 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 11 | 0.0171 | 9.64 | 4.604 | 0.3424 | 63.0 | 623.07 | 7074.44 | 91176.4 | 0.4927 | 0.1584 | 0.0077 | 0.0045 | 0.0406 | 0.0095 | 0.0981 | 0.0305 | 0.1678 | 0.0652 | 0.2278 | 0.1209 | 0.2100 | 0.1971 | 0.1593 | 0.2556 | 0.0768 | 0.2221 | 0.0121 | 0.0947 | 0.0010 | 0.0002 | 0.0055 | 0.0018 | 0.0185 | 0.0077 | 0.0480 | 0.0279 | 0.0854 | 0.0599 | 0.1434 | 0.1145 | 0.1875 | 0.1703 | 0.2216 | 0.2463 | 0.2890 | 0.3715 | 0.1040 | 0.1438 | 0.1361 | 0.1222 | 0.1301 | 0.0872 | 0.0853 | 0.0745 | 0.0895 | 0.1058 | 0.0811 | 0.0857 | 0.0956 | 0.0842 | 0.0923 | 0.1170 | 0.1860 | 0.1796 | 0.0135 | 0.0521 | 0.0974 | 0.1372 | 0.1573 | 0.1377 | 0.1213 | 0.1143 | 0.1691 |