High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 659 | 864 | | 9157 | 12600 | 572.9 | 114.09 | 133.84 | 114.82 | 435 | 475 | 505 | 534 | 563 | 594 | 628 | 666 | 723 | 0.0900 | 1134 | 1.199 | 96.51 | 40.61 | 1 | 0.0284 | 260 | 0.0005 | 84.01 | 7.780 | 0.1396 | 341248.0 | 211000000 | 136000000000 | 90100000000000 | 0.4173 | 0.2328 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0013 | 0.0001 | 0.0084 | 0.0014 | 0.0529 | 0.0133 | 0.1231 | 0.0303 | 0.1329 | 0.0280 | 0.1634 | 0.0394 | 0.5172 | 0.8876 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0045 | 0.0001 | 0.0267 | 0.0098 | 0.0603 | 0.0210 | 0.0668 | 0.0155 | 0.0864 | 0.0211 | 0.7545 | 0.9324 | 0.0022 | 0.0060 | 0.0129 | 0.0121 | 0.0237 | 0.0423 | 0.0760 | 0.0755 | 0.1097 | 0.1631 | 0.1627 | 0.1450 | 0.0968 | 0.1329 | 0.1168 | 0.1541 | 0.3993 | 0.2689 | 0.0000 | 0.0012 | 0.0046 | 0.0244 | 0.0835 | 0.1249 | 0.1047 | 0.1165 | 0.5403 | 14 | 26 | 50 | 78 | 106 | 138 | 176 | 224 | 297 | 0.0077 | 28.76 | 6.275 | 0.3483 | 31096.2 | 9370000 | 3320000000 | 1310000000000 | 0.6019 | 0.1025 | 0.0320 | 0.0017 | 0.1338 | 0.0087 | 0.2500 | 0.0546 | 0.1658 | 0.1008 | 0.1684 | 0.1801 | 0.1271 | 0.1957 | 0.0646 | 0.1465 | 0.0413 | 0.1349 | 0.0170 | 0.1769 | 0.0005 | 0.0004 | 0.0008 | 0.0005 | 0.0031 | 0.0019 | 0.0161 | 0.0096 | 0.0663 | 0.0503 | 0.1259 | 0.0945 | 0.0830 | 0.0727 | 0.1216 | 0.1056 | 0.5828 | 0.6645 | 0.0009 | 0.0012 | 0.0042 | 0.0084 | 0.0093 | 0.0160 | 0.0313 | 0.0389 | 0.1011 | 0.1062 | 0.1497 | 0.1596 | 0.1025 | 0.1120 | 0.1383 | 0.1416 | 0.4626 | 0.4161 | 0.0008 | 0.0029 | 0.0060 | 0.0229 | 0.0836 | 0.1434 | 0.0928 | 0.1261 | 0.5216 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 623 | 128 | | 5953 | 11599 | 530.3 | 117.08 | 264.39 | 415.53 | 392 | 428 | 458 | 485 | 513 | 546 | 584 | 630 | 696 | 0.0813 | 943 | 0.967 | 130.08 | 35.78 | 1 | 0.0519 | 309 | 0.0004 | 120.83 | 7.914 | 0.1104 | 294936.0 | 172000000 | 105000000000 | 66500000000000 | 0.4302 | 0.2128 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0059 | 0.0004 | 0.0185 | 0.0013 | 0.0765 | 0.0215 | 0.1506 | 0.0396 | 0.1458 | 0.0420 | 0.1956 | 0.0637 | 0.4064 | 0.8314 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0035 | 0.0000 | 0.0076 | 0.0003 | 0.0384 | 0.0137 | 0.0657 | 0.0215 | 0.0657 | 0.0178 | 0.0966 | 0.0280 | 0.7218 | 0.9187 | 0.0044 | 0.0061 | 0.0000 | 0.0214 | 0.0142 | 0.0428 | 0.0567 | 0.1284 | 0.1258 | 0.1743 | 0.1709 | 0.2110 | 0.1116 | 0.1376 | 0.1515 | 0.1407 | 0.3649 | 0.1376 | 0.0015 | 0.0015 | 0.0083 | 0.0326 | 0.0701 | 0.1227 | 0.0848 | 0.1148 | 0.5638 | 9 | 12 | 15 | 20 | 32 | 87 | 235 | 532 | 918 | 0.0999 | 84.61 | 5.018 | 0.5316 | 242548.0 | 294000000 | 414000000000 | 650000000000000 | 0.4380 | 0.2212 | 0.0713 | 0.0000 | 0.2240 | 0.0143 | 0.2261 | 0.1554 | 0.1344 | 0.1964 | 0.1303 | 0.1954 | 0.0876 | 0.1573 | 0.0448 | 0.0925 | 0.0407 | 0.0944 | 0.0407 | 0.0944 | 0.0006 | 0.0000 | 0.0003 | 0.0013 | 0.0014 | 0.0020 | 0.0089 | 0.0075 | 0.0371 | 0.0362 | 0.0674 | 0.0619 | 0.0438 | 0.0415 | 0.0726 | 0.0714 | 0.7680 | 0.7782 | 0.0006 | 0.0000 | 0.0000 | 0.0007 | 0.0013 | 0.0014 | 0.0055 | 0.0051 | 0.0375 | 0.0471 | 0.0789 | 0.0792 | 0.0465 | 0.0567 | 0.0818 | 0.0857 | 0.7478 | 0.7240 | 0.0003 | 0.0030 | 0.0021 | 0.0087 | 0.0382 | 0.0659 | 0.0454 | 0.0728 | 0.7636 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 459 | 658 | | 11362 | 20851 | 286.6 | 57.22 | 160.43 | 166.77 | 216 | 238 | 254 | 268 | 283 | 297 | 315 | 335 | 362 | 0.0609 | 1269 | 1.250 | 84.58 | 36.89 | 1 | 0.0202 | 229 | 0.0006 | 69.33 | 7.619 | 0.1453 | 85435.4 | 26400000 | 8470000000 | 2810000000000 | 0.3998 | 0.2496 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0000 | 0.0151 | 0.0008 | 0.0564 | 0.0119 | 0.1324 | 0.0353 | 0.1449 | 0.0348 | 0.1680 | 0.0534 | 0.4798 | 0.8638 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0057 | 0.0004 | 0.0244 | 0.0088 | 0.0561 | 0.0236 | 0.0596 | 0.0148 | 0.0768 | 0.0231 | 0.7756 | 0.9293 | 0.0061 | 0.0143 | 0.0094 | 0.0544 | 0.0304 | 0.0716 | 0.0839 | 0.1777 | 0.1733 | 0.2521 | 0.1926 | 0.1519 | 0.1291 | 0.0917 | 0.1512 | 0.0974 | 0.2241 | 0.0888 | 0.0015 | 0.0022 | 0.0078 | 0.0347 | 0.0806 | 0.1342 | 0.1129 | 0.1362 | 0.4899 | 14 | 18 | 28 | 51 | 95 | 156 | 222 | 299 | 405 | 0.0196 | 36.84 | 6.010 | 0.3723 | 53550.1 | 23300000 | 11800000000 | 6650000000000 | 0.5064 | 0.1481 | 0.0625 | 0.0012 | 0.2600 | 0.0157 | 0.3022 | 0.1503 | 0.1409 | 0.1993 | 0.0988 | 0.2074 | 0.0736 | 0.1703 | 0.0334 | 0.0942 | 0.0252 | 0.0818 | 0.0034 | 0.0799 | 0.0001 | 0.0000 | 0.0004 | 0.0005 | 0.0019 | 0.0015 | 0.0115 | 0.0099 | 0.0600 | 0.0532 | 0.1157 | 0.0968 | 0.0747 | 0.0636 | 0.1141 | 0.0984 | 0.6214 | 0.6761 | 0.0004 | 0.0010 | 0.0028 | 0.0037 | 0.0065 | 0.0110 | 0.0223 | 0.0260 | 0.0761 | 0.0864 | 0.1468 | 0.1528 | 0.0956 | 0.1004 | 0.1209 | 0.1293 | 0.5286 | 0.4895 | 0.0000 | 0.0010 | 0.0039 | 0.0157 | 0.0717 | 0.1279 | 0.0896 | 0.1188 | 0.5713 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 727 | 410 | | 4323 | 18730 | 284.9 | 68.71 | 48.75 | 82.54 | 205 | 226 | 243 | 259 | 275 | 295 | 317 | 340 | 377 | 0.0526 | 985 | 0.713 | 167.73 | 44.42 | 1 | 0.1020 | 441 | 0.0010 | 43.50 | 7.099 | 0.1678 | 85895.4 | 27400000 | 9230000000 | 3280000000000 | 0.4160 | 0.2277 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0066 | 0.0000 | 0.0210 | 0.0018 | 0.0798 | 0.0225 | 0.1736 | 0.0513 | 0.1569 | 0.0548 | 0.1853 | 0.0791 | 0.3760 | 0.7905 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0000 | 0.0082 | 0.0009 | 0.0360 | 0.0172 | 0.0703 | 0.0289 | 0.0670 | 0.0280 | 0.0861 | 0.0407 | 0.7289 | 0.8843 | 0.0059 | 0.0118 | 0.0071 | 0.0078 | 0.0142 | 0.0510 | 0.0673 | 0.0980 | 0.1311 | 0.1922 | 0.1865 | 0.1961 | 0.1074 | 0.1059 | 0.1287 | 0.1216 | 0.3518 | 0.2157 | 0.0021 | 0.0010 | 0.0088 | 0.0247 | 0.0809 | 0.1108 | 0.0876 | 0.1221 | 0.5621 | 6 | 8 | 9 | 11 | 13 | 18 | 32 | 65 | 143 | 0.1830 | 2.23 | 3.000 | 0.7083 | 9189.6 | 2810000 | 1040000000 | 430000000000 | 0.5119 | 0.1460 | 0.0261 | 0.0044 | 0.0782 | 0.0114 | 0.1583 | 0.0409 | 0.1676 | 0.0735 | 0.1918 | 0.1395 | 0.1629 | 0.1883 | 0.1006 | 0.1280 | 0.0726 | 0.1513 | 0.0419 | 0.2626 | 0.0010 | 0.0014 | 0.0014 | 0.0020 | 0.0028 | 0.0041 | 0.0130 | 0.0112 | 0.0434 | 0.0338 | 0.0578 | 0.0500 | 0.0580 | 0.0465 | 0.0811 | 0.0695 | 0.7414 | 0.7815 | 0.0000 | 0.0000 | 0.0018 | 0.0028 | 0.0040 | 0.0050 | 0.0143 | 0.0160 | 0.0564 | 0.0607 | 0.0804 | 0.0958 | 0.0666 | 0.0668 | 0.0927 | 0.0914 | 0.6839 | 0.6616 | 0.0000 | 0.0027 | 0.0049 | 0.0151 | 0.0457 | 0.0722 | 0.0624 | 0.0849 | 0.7122 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 212 | 744 | | 6614 | 10325 | 163.1 | 32.35 | 119.28 | 84.78 | 125 | 138 | 147 | 155 | 161 | 167 | 175 | 185 | 203 | 0.0792 | 818 | 1.172 | 127.35 | 40.25 | 1 | 0.0452 | 299 | 0.0020 | 27.70 | 6.559 | 0.2300 | 27650.6 | 4880000 | 902000000 | 175000000000 | 0.4500 | 0.2031 | 0.0002 | 0.0000 | 0.0008 | 0.0003 | 0.0033 | 0.0005 | 0.0157 | 0.0009 | 0.0518 | 0.0158 | 0.1045 | 0.0311 | 0.1239 | 0.0356 | 0.1680 | 0.0538 | 0.5318 | 0.8621 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0073 | 0.0005 | 0.0238 | 0.0110 | 0.0514 | 0.0224 | 0.0550 | 0.0146 | 0.0835 | 0.0286 | 0.7771 | 0.9229 | 0.0114 | 0.0090 | 0.0194 | 0.0495 | 0.0411 | 0.0495 | 0.1006 | 0.1802 | 0.1600 | 0.2117 | 0.1794 | 0.1757 | 0.1486 | 0.0991 | 0.1394 | 0.0991 | 0.2000 | 0.1261 | 0.0006 | 0.0063 | 0.0157 | 0.0466 | 0.0913 | 0.1326 | 0.1222 | 0.1698 | 0.4148 | 30 | 47 | 62 | 79 | 97 | 119 | 148 | 185 | 240 | 0.0026 | 32.10 | 6.579 | 0.2832 | 21415.5 | 4970000 | 1370000000 | 425000000000 | 0.5726 | 0.1051 | 0.0233 | 0.0012 | 0.1341 | 0.0059 | 0.2743 | 0.0446 | 0.1832 | 0.1006 | 0.1522 | 0.1877 | 0.1071 | 0.1954 | 0.0694 | 0.1475 | 0.0367 | 0.1460 | 0.0197 | 0.1709 | 0.0004 | 0.0005 | 0.0023 | 0.0009 | 0.0082 | 0.0027 | 0.0218 | 0.0148 | 0.0827 | 0.0624 | 0.1269 | 0.0968 | 0.1019 | 0.0859 | 0.1392 | 0.1237 | 0.5166 | 0.6124 | 0.0015 | 0.0023 | 0.0073 | 0.0051 | 0.0094 | 0.0167 | 0.0462 | 0.0607 | 0.1152 | 0.1293 | 0.1711 | 0.1795 | 0.1100 | 0.1215 | 0.1510 | 0.1484 | 0.3883 | 0.3364 | 0.0007 | 0.0041 | 0.0070 | 0.0374 | 0.0934 | 0.1539 | 0.1074 | 0.1421 | 0.4540 | ||
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 547 | 289 | | 11285 | 27072 | 244.5 | 58.73 | 197.38 | 232.26 | 172 | 193 | 209 | 224 | 239 | 255 | 274 | 296 | 325 | 0.0436 | 1181 | 1.186 | 113.74 | 45.89 | 1 | 0.0262 | 296 | 0.0006 | 59.04 | 7.598 | 0.1608 | 63242.6 | 17200000 | 4920000000 | 1470000000000 | 0.4595 | 0.1977 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0003 | 0.0222 | 0.0030 | 0.0838 | 0.0183 | 0.1665 | 0.0428 | 0.1519 | 0.0447 | 0.1695 | 0.0687 | 0.4015 | 0.8221 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0009 | 0.0000 | 0.0056 | 0.0015 | 0.0329 | 0.0117 | 0.0689 | 0.0232 | 0.0624 | 0.0202 | 0.0836 | 0.0302 | 0.7454 | 0.9132 | 0.0042 | 0.0118 | 0.0042 | 0.0251 | 0.0161 | 0.0340 | 0.0589 | 0.0991 | 0.1158 | 0.1731 | 0.1866 | 0.1864 | 0.1001 | 0.1080 | 0.1387 | 0.1391 | 0.3753 | 0.2234 | 0.0010 | 0.0019 | 0.0079 | 0.0250 | 0.0784 | 0.1238 | 0.0992 | 0.1291 | 0.5338 | 14 | 18 | 26 | 48 | 94 | 162 | 255 | 375 | 541 | 0.0240 | 59.33 | 6.100 | 0.4045 | 92900.8 | 59800000 | 46700000000 | 42500000000000 | 0.3821 | 0.2440 | 0.0415 | 0.0013 | 0.1747 | 0.0119 | 0.3178 | 0.1184 | 0.1407 | 0.1403 | 0.1199 | 0.1896 | 0.0884 | 0.1946 | 0.0465 | 0.1232 | 0.0336 | 0.1013 | 0.0369 | 0.1196 | 0.0001 | 0.0002 | 0.0000 | 0.0003 | 0.0009 | 0.0010 | 0.0080 | 0.0057 | 0.0480 | 0.0394 | 0.0973 | 0.0776 | 0.0603 | 0.0509 | 0.0905 | 0.0756 | 0.6949 | 0.7492 | 0.0002 | 0.0004 | 0.0020 | 0.0014 | 0.0027 | 0.0026 | 0.0159 | 0.0171 | 0.0664 | 0.0775 | 0.1207 | 0.1335 | 0.0813 | 0.0857 | 0.1106 | 0.1232 | 0.6001 | 0.5585 | 0.0001 | 0.0006 | 0.0019 | 0.0122 | 0.0586 | 0.1142 | 0.0705 | 0.1007 | 0.6412 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 293 | 422 | | 7600 | 17600 | 391.5 | 79.06 | 96.65 | 175.15 | 294 | 323 | 346 | 368 | 387 | 407 | 428 | 454 | 494 | 0.0666 | 1173 | 1.027 | 120.93 | 40.26 | 1 | 0.0393 | 299 | 0.0010 | 42.54 | 7.175 | 0.1809 | 159521.0 | 67600000 | 29700000000 | 13600000000000 | 0.4253 | 0.2170 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0029 | 0.0001 | 0.0171 | 0.0012 | 0.0549 | 0.0162 | 0.1019 | 0.0305 | 0.1266 | 0.0305 | 0.1577 | 0.0455 | 0.5378 | 0.8759 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0001 | 0.0070 | 0.0008 | 0.0228 | 0.0109 | 0.0451 | 0.0198 | 0.0570 | 0.0134 | 0.0686 | 0.0214 | 0.7973 | 0.9336 | 0.0076 | 0.0156 | 0.0143 | 0.0430 | 0.0227 | 0.0352 | 0.0714 | 0.1211 | 0.1294 | 0.1953 | 0.1723 | 0.2305 | 0.1445 | 0.1367 | 0.1437 | 0.0977 | 0.2941 | 0.1250 | 0.0016 | 0.0033 | 0.0068 | 0.0256 | 0.0698 | 0.1192 | 0.1121 | 0.1367 | 0.5248 | 7 | 8 | 10 | 12 | 15 | 25 | 57 | 139 | 334 | 0.1858 | 26.15 | 3.861 | 0.6358 | 40015.7 | 24500000 | 18000000000 | 15000000000000 | 0.4382 | 0.1915 | 0.0832 | 0.0054 | 0.2774 | 0.0380 | 0.2825 | 0.1739 | 0.1261 | 0.1618 | 0.0870 | 0.2101 | 0.0542 | 0.1540 | 0.0429 | 0.0936 | 0.0366 | 0.0713 | 0.0101 | 0.0918 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0011 | 0.0015 | 0.0121 | 0.0107 | 0.0607 | 0.0574 | 0.0962 | 0.0804 | 0.0626 | 0.0563 | 0.0962 | 0.0923 | 0.6700 | 0.7009 | 0.0000 | 0.0003 | 0.0005 | 0.0003 | 0.0023 | 0.0006 | 0.0143 | 0.0109 | 0.0696 | 0.0836 | 0.1222 | 0.1310 | 0.0703 | 0.0729 | 0.1126 | 0.1203 | 0.6081 | 0.5802 | 0.0000 | 0.0007 | 0.0012 | 0.0145 | 0.0655 | 0.1071 | 0.0700 | 0.1014 | 0.6396 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 580 | 433 | | 1493 | 7000 | 280.3 | 39.92 | 26.94 | 45.70 | 230 | 246 | 259 | 269 | 278 | 289 | 298 | 312 | 333 | 0.0730 | 511 | 0.722 | 72.57 | 16.03 | 1 | 0.1092 | 163 | 0.0044 | 8.62 | 5.687 | 0.3499 | 80150.8 | 23400000 | 6950000000 | 2110000000000 | 0.4223 | 0.2148 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0007 | 0.0385 | 0.0235 | 0.0577 | 0.0450 | 0.0513 | 0.0215 | 0.0810 | 0.0403 | 0.7642 | 0.8690 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0007 | 0.0246 | 0.0221 | 0.0377 | 0.0442 | 0.0261 | 0.0181 | 0.0399 | 0.0328 | 0.8681 | 0.8821 | 0.0226 | 0.2000 | 0.0150 | 0.2000 | 0.0526 | 0.4000 | 0.0677 | 0.2000 | 0.0602 | 0.0000 | 0.1053 | 0.0000 | 0.0902 | 0.0000 | 0.1278 | 0.0000 | 0.4586 | 0.0000 | 0.0014 | 0.0014 | 0.0069 | 0.0220 | 0.0495 | 0.0755 | 0.0975 | 0.1319 | 0.6140 | 7 | 8 | 9 | 10 | 12 | 15 | 20 | 33 | 57 | 0.2933 | 1.67 | 2.358 | 0.8342 | 2814.2 | 777978 | 343000000 | 188000000000 | 0.6091 | 0.1098 | 0.0437 | 0.0353 | 0.0542 | 0.0453 | 0.0822 | 0.0637 | 0.1014 | 0.0599 | 0.1294 | 0.0860 | 0.1451 | 0.1083 | 0.1521 | 0.1045 | 0.1573 | 0.1421 | 0.1346 | 0.3548 | 0.0065 | 0.0172 | 0.0101 | 0.0192 | 0.0081 | 0.0204 | 0.0141 | 0.0188 | 0.0252 | 0.0337 | 0.0348 | 0.0425 | 0.0403 | 0.0357 | 0.0685 | 0.0665 | 0.7924 | 0.7459 | 0.0035 | 0.0050 | 0.0042 | 0.0084 | 0.0099 | 0.0168 | 0.0156 | 0.0218 | 0.0453 | 0.0536 | 0.0545 | 0.0662 | 0.0630 | 0.0679 | 0.1288 | 0.1274 | 0.6752 | 0.6329 | 0.0024 | 0.0047 | 0.0082 | 0.0141 | 0.0294 | 0.0500 | 0.0488 | 0.1106 | 0.7318 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 308 | 884 | | 5050 | 10182 | 749.7 | 126.97 | 42.65 | 71.54 | 594 | 652 | 686 | 713 | 737 | 762 | 805 | 871 | 942 | 0.0693 | 706 | 1.198 | 99.81 | 37.54 | 1 | 0.0493 | 249 | 0.0009 | 44.07 | 7.331 | 0.2040 | 578151.0 | 458000000 | 371000000000 | 308000000000000 | 0.4226 | 0.2196 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0027 | 0.0000 | 0.0068 | 0.0006 | 0.0285 | 0.0120 | 0.0415 | 0.0212 | 0.0388 | 0.0132 | 0.0616 | 0.0186 | 0.8190 | 0.9345 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0020 | 0.0006 | 0.0159 | 0.0120 | 0.0237 | 0.0212 | 0.0190 | 0.0116 | 0.0326 | 0.0178 | 0.9061 | 0.9369 | 0.0036 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0000 | 0.0169 | 1.0000 | 0.0495 | 0.0000 | 0.0579 | 0.0000 | 0.0760 | 0.0000 | 0.0893 | 0.0000 | 0.7045 | 0.0000 | 0.0027 | 0.0054 | 0.0125 | 0.0152 | 0.0411 | 0.0438 | 0.0585 | 0.0688 | 0.7520 | 6 | 8 | 9 | 11 | 13 | 19 | 36 | 60 | 109 | 0.1640 | 2.95 | 2.935 | 0.7102 | 6935.9 | 2170000 | 941000000 | 501000000000 | 0.4404 | 0.1899 | 0.0194 | 0.0075 | 0.0535 | 0.0125 | 0.1069 | 0.0337 | 0.1470 | 0.0580 | 0.1701 | 0.1079 | 0.1750 | 0.1341 | 0.1665 | 0.1248 | 0.1130 | 0.1622 | 0.0486 | 0.3593 | 0.0013 | 0.0014 | 0.0041 | 0.0022 | 0.0048 | 0.0064 | 0.0153 | 0.0160 | 0.0396 | 0.0329 | 0.0616 | 0.0440 | 0.0517 | 0.0442 | 0.0727 | 0.0650 | 0.7490 | 0.7879 | 0.0017 | 0.0020 | 0.0043 | 0.0035 | 0.0108 | 0.0055 | 0.0208 | 0.0179 | 0.0554 | 0.0546 | 0.0705 | 0.0789 | 0.0575 | 0.0645 | 0.0809 | 0.0904 | 0.6981 | 0.6827 | 0.0015 | 0.0037 | 0.0104 | 0.0186 | 0.0443 | 0.0707 | 0.0592 | 0.0878 | 0.7039 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 357 | 710 | | 4921 | 10409 | 582.7 | 104.04 | 163.34 | 169.37 | 446 | 495 | 525 | 552 | 579 | 603 | 634 | 667 | 722 | 0.0790 | 822 | 1.185 | 96.46 | 39.82 | 1 | 0.0528 | 260 | 0.0007 | 60.83 | 7.459 | 0.1592 | 350308.0 | 217000000 | 138000000000 | 90400000000000 | 0.4237 | 0.2197 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0017 | 0.0004 | 0.0084 | 0.0015 | 0.0427 | 0.0174 | 0.0858 | 0.0245 | 0.0936 | 0.0272 | 0.1375 | 0.0367 | 0.6295 | 0.8923 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0031 | 0.0002 | 0.0252 | 0.0151 | 0.0417 | 0.0191 | 0.0370 | 0.0165 | 0.0620 | 0.0242 | 0.8301 | 0.9248 | 0.0075 | 0.0326 | 0.0090 | 0.0000 | 0.0271 | 0.0761 | 0.0827 | 0.1739 | 0.1203 | 0.1739 | 0.1399 | 0.2391 | 0.1068 | 0.1413 | 0.1053 | 0.1087 | 0.4015 | 0.0543 | 0.0017 | 0.0034 | 0.0029 | 0.0253 | 0.0623 | 0.1077 | 0.1098 | 0.1355 | 0.5513 | 11 | 14 | 21 | 52 | 104 | 160 | 229 | 315 | 422 | 0.0230 | 43.80 | 6.033 | 0.3963 | 55363.2 | 23600000 | 11400000000 | 6020000000000 | 0.5634 | 0.1337 | 0.0386 | 0.0005 | 0.1929 | 0.0101 | 0.2671 | 0.0648 | 0.1977 | 0.1411 | 0.1244 | 0.2046 | 0.0839 | 0.1945 | 0.0473 | 0.1177 | 0.0260 | 0.1172 | 0.0222 | 0.1494 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0024 | 0.0004 | 0.0120 | 0.0066 | 0.0468 | 0.0368 | 0.0843 | 0.0643 | 0.0646 | 0.0509 | 0.1058 | 0.0885 | 0.6839 | 0.7518 | 0.0008 | 0.0003 | 0.0011 | 0.0016 | 0.0036 | 0.0038 | 0.0149 | 0.0166 | 0.0618 | 0.0787 | 0.1118 | 0.1234 | 0.0845 | 0.0918 | 0.1220 | 0.1321 | 0.5995 | 0.5516 | 0.0005 | 0.0010 | 0.0027 | 0.0124 | 0.0553 | 0.0981 | 0.0694 | 0.1131 | 0.6476 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 566 | 807 | | 4751 | 7725 | 404.9 | 192.17 | 127.70 | 196.98 | 142 | 186 | 268 | 341 | 396 | 464 | 540 | 611 | 670 | 0.1111 | 858 | 1.078 | 54.04 | 18.87 | 1 | 0.0280 | 133 | 0.0027 | 8.16 | 6.352 | 0.3795 | 200834.0 | 112000000 | 66500000000 | 41200000000000 | 0.3420 | 0.2744 | 0.0000 | 0.0005 | 0.0008 | 0.0005 | 0.0016 | 0.0005 | 0.0219 | 0.0064 | 0.0926 | 0.0401 | 0.1300 | 0.0724 | 0.1024 | 0.0519 | 0.1446 | 0.0738 | 0.5061 | 0.7540 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0003 | 0.0189 | 0.0153 | 0.0314 | 0.0269 | 0.0245 | 0.0136 | 0.0453 | 0.0266 | 0.8762 | 0.9173 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0011 | 0.0008 | 0.0050 | 0.0111 | 0.0296 | 0.0325 | 0.0369 | 0.0507 | 0.0335 | 0.0428 | 0.0464 | 0.0642 | 0.8475 | 0.7971 | 0.0000 | 0.0004 | 0.0000 | 0.0104 | 0.0265 | 0.0370 | 0.0313 | 0.0487 | 0.8456 | 7 | 9 | 11 | 16 | 28 | 63 | 121 | 222 | 412 | 0.0706 | 13.58 | 4.145 | 0.5200 | 55103.2 | 34600000 | 26500000000 | 23100000000000 | 0.6752 | 0.0630 | 0.0314 | 0.0009 | 0.1458 | 0.0204 | 0.2288 | 0.0814 | 0.1513 | 0.1230 | 0.1439 | 0.1748 | 0.1328 | 0.1832 | 0.0627 | 0.1221 | 0.0424 | 0.1240 | 0.0609 | 0.1702 | 0.0008 | 0.0000 | 0.0008 | 0.0003 | 0.0020 | 0.0007 | 0.0106 | 0.0115 | 0.0701 | 0.0687 | 0.1133 | 0.0965 | 0.0830 | 0.0767 | 0.1251 | 0.1154 | 0.5943 | 0.6302 | 0.0015 | 0.0000 | 0.0035 | 0.0028 | 0.0095 | 0.0084 | 0.0160 | 0.0302 | 0.0845 | 0.0878 | 0.1191 | 0.1270 | 0.1046 | 0.1079 | 0.1251 | 0.1208 | 0.5363 | 0.5151 | 0.0000 | 0.0013 | 0.0013 | 0.0191 | 0.0756 | 0.1250 | 0.0894 | 0.1299 | 0.5583 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1219 | 611 | | 6727 | 10795 | 500.4 | 87.18 | 61.57 | 164.61 | 389 | 436 | 464 | 484 | 500 | 519 | 539 | 564 | 613 | 0.0766 | 827 | 0.887 | 151.21 | 35.90 | 4 | 0.0523 | 352 | 0.0010 | 40.11 | 7.197 | 0.1973 | 258004.0 | 137000000 | 74100000000 | 41200000000000 | 0.4599 | 0.1961 | 0.0006 | 0.0000 | 0.0008 | 0.0000 | 0.0006 | 0.0000 | 0.0061 | 0.0005 | 0.0334 | 0.0138 | 0.0743 | 0.0305 | 0.0688 | 0.0200 | 0.0981 | 0.0361 | 0.7174 | 0.8992 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0002 | 0.0203 | 0.0122 | 0.0431 | 0.0268 | 0.0321 | 0.0141 | 0.0475 | 0.0242 | 0.8540 | 0.9226 | 0.0036 | 0.0385 | 0.0109 | 0.0641 | 0.0243 | 0.0256 | 0.0510 | 0.1282 | 0.0875 | 0.2179 | 0.1179 | 0.2179 | 0.0899 | 0.1026 | 0.1118 | 0.1026 | 0.5030 | 0.1026 | 0.0015 | 0.0026 | 0.0100 | 0.0280 | 0.0665 | 0.1130 | 0.0971 | 0.1266 | 0.5546 | 5 | 5 | 7 | 8 | 9 | 10 | 12 | 20 | 145 | 0.3474 | 14.59 | 2.480 | 0.7590 | 30885.0 | 22100000 | 18100000000 | 16500000000000 | 0.6221 | 0.0747 | 0.0404 | 0.0026 | 0.1515 | 0.0289 | 0.2172 | 0.0525 | 0.2071 | 0.1732 | 0.1515 | 0.2310 | 0.1414 | 0.2047 | 0.0505 | 0.1260 | 0.0303 | 0.0866 | 0.0101 | 0.0945 | 0.0000 | 0.0006 | 0.0006 | 0.0030 | 0.0032 | 0.0024 | 0.0121 | 0.0119 | 0.0401 | 0.0351 | 0.0650 | 0.0660 | 0.0510 | 0.0463 | 0.0643 | 0.0564 | 0.7637 | 0.7784 | 0.0000 | 0.0000 | 0.0015 | 0.0015 | 0.0015 | 0.0038 | 0.0175 | 0.0215 | 0.0445 | 0.0445 | 0.0729 | 0.0722 | 0.0590 | 0.0507 | 0.0649 | 0.0753 | 0.7383 | 0.7304 | 0.0000 | 0.0014 | 0.0020 | 0.0143 | 0.0442 | 0.0626 | 0.0558 | 0.0721 | 0.7476 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1189 | 718 | | 4088 | 19318 | 453.0 | 106.58 | 96.23 | 99.59 | 325 | 357 | 386 | 412 | 441 | 469 | 504 | 546 | 607 | 0.0500 | 965 | 1.115 | 111.23 | 32.65 | 1 | 0.0624 | 255 | 0.0007 | 67.51 | 7.409 | 0.1424 | 216555.0 | 109000000 | 57400000000 | 31500000000000 | 0.4176 | 0.2368 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0042 | 0.0003 | 0.0275 | 0.0040 | 0.0803 | 0.0242 | 0.1695 | 0.0594 | 0.1357 | 0.0548 | 0.1682 | 0.0698 | 0.4134 | 0.7875 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0100 | 0.0017 | 0.0344 | 0.0160 | 0.0821 | 0.0397 | 0.0581 | 0.0242 | 0.0865 | 0.0410 | 0.7264 | 0.8774 | 0.0012 | 0.0071 | 0.0084 | 0.0000 | 0.0096 | 0.0249 | 0.0646 | 0.1068 | 0.0969 | 0.1459 | 0.1352 | 0.1851 | 0.1172 | 0.1281 | 0.1148 | 0.1637 | 0.4522 | 0.2384 | 0.0016 | 0.0043 | 0.0070 | 0.0290 | 0.0774 | 0.1198 | 0.0956 | 0.1263 | 0.5390 | 8 | 11 | 16 | 33 | 63 | 99 | 134 | 174 | 230 | 0.0320 | 16.16 | 5.428 | 0.4394 | 19177.9 | 5220000 | 1780000000 | 719000000000 | 0.4849 | 0.1488 | 0.0329 | 0.0012 | 0.1667 | 0.0102 | 0.2528 | 0.0730 | 0.1924 | 0.1400 | 0.1450 | 0.1900 | 0.1015 | 0.2083 | 0.0551 | 0.1299 | 0.0343 | 0.1220 | 0.0193 | 0.1254 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0020 | 0.0012 | 0.0104 | 0.0077 | 0.0520 | 0.0427 | 0.0878 | 0.0780 | 0.0668 | 0.0541 | 0.0945 | 0.0813 | 0.6857 | 0.7349 | 0.0007 | 0.0007 | 0.0022 | 0.0028 | 0.0048 | 0.0102 | 0.0188 | 0.0254 | 0.0667 | 0.0816 | 0.1172 | 0.1331 | 0.0893 | 0.0932 | 0.1224 | 0.1264 | 0.5778 | 0.5265 | 0.0004 | 0.0004 | 0.0035 | 0.0151 | 0.0545 | 0.1053 | 0.0729 | 0.1062 | 0.6416 | ||
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 776 | 533 | | 11980 | 33861 | 383.5 | 82.50 | 120.63 | 176.56 | 283 | 310 | 334 | 355 | 376 | 398 | 421 | 451 | 496 | 0.0356 | 1205 | 1.136 | 140.66 | 55.15 | 1 | 0.0313 | 375 | 0.0009 | 37.01 | 7.234 | 0.1929 | 153867.0 | 64500000 | 28200000000 | 12800000000000 | 0.4493 | 0.2003 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0028 | 0.0000 | 0.0182 | 0.0008 | 0.0630 | 0.0134 | 0.1320 | 0.0320 | 0.1379 | 0.0333 | 0.1599 | 0.0519 | 0.4853 | 0.8686 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0010 | 0.0000 | 0.0076 | 0.0001 | 0.0277 | 0.0090 | 0.0540 | 0.0170 | 0.0581 | 0.0126 | 0.0745 | 0.0212 | 0.7764 | 0.9401 | 0.0019 | 0.0113 | 0.0047 | 0.0244 | 0.0159 | 0.0357 | 0.0637 | 0.1429 | 0.1404 | 0.1560 | 0.1807 | 0.2237 | 0.1147 | 0.0977 | 0.1470 | 0.1278 | 0.3310 | 0.1805 | 0.0004 | 0.0018 | 0.0069 | 0.0208 | 0.0738 | 0.1090 | 0.1005 | 0.1337 | 0.5532 | 7 | 8 | 10 | 13 | 28 | 71 | 135 | 223 | 358 | 0.1025 | 9.69 | 4.335 | 0.5557 | 45723.5 | 25300000 | 17600000000 | 14200000000000 | 0.3892 | 0.2409 | 0.0580 | 0.0013 | 0.2129 | 0.0223 | 0.2772 | 0.1129 | 0.1731 | 0.1468 | 0.1215 | 0.2079 | 0.0876 | 0.1983 | 0.0398 | 0.1203 | 0.0207 | 0.0982 | 0.0093 | 0.0921 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0008 | 0.0004 | 0.0071 | 0.0056 | 0.0520 | 0.0410 | 0.0868 | 0.0707 | 0.0678 | 0.0584 | 0.0917 | 0.0804 | 0.6937 | 0.7434 | 0.0005 | 0.0002 | 0.0012 | 0.0009 | 0.0018 | 0.0021 | 0.0154 | 0.0152 | 0.0663 | 0.0760 | 0.1097 | 0.1251 | 0.0819 | 0.0859 | 0.1104 | 0.1159 | 0.6128 | 0.5786 | 0.0001 | 0.0003 | 0.0013 | 0.0107 | 0.0581 | 0.1011 | 0.0739 | 0.1012 | 0.6533 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 512 | 618 | | 11255 | 20255 | 428.2 | 87.05 | 105.63 | 203.30 | 309 | 354 | 384 | 408 | 429 | 449 | 474 | 501 | 549 | 0.0544 | 1102 | 0.683 | 111.73 | 25.46 | 6 | 0.0275 | 310 | 0.0009 | 22.99 | 7.263 | 0.2438 | 190902.0 | 88200000 | 42000000000 | 20600000000000 | 0.4424 | 0.2031 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0026 | 0.0004 | 0.0084 | 0.0012 | 0.0280 | 0.0134 | 0.0584 | 0.0238 | 0.0474 | 0.0178 | 0.0713 | 0.0278 | 0.7829 | 0.9155 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0033 | 0.0008 | 0.0135 | 0.0104 | 0.0281 | 0.0209 | 0.0204 | 0.0124 | 0.0313 | 0.0184 | 0.9022 | 0.9370 | 0.0011 | 0.0000 | 0.0063 | 0.0000 | 0.0110 | 0.0000 | 0.0226 | 0.0000 | 0.0479 | 0.0000 | 0.0805 | 0.0000 | 0.0642 | 0.0000 | 0.0789 | 0.0000 | 0.6875 | 0.0000 | 0.0009 | 0.0019 | 0.0058 | 0.0140 | 0.0333 | 0.0539 | 0.0552 | 0.0744 | 0.7606 | 8 | 9 | 10 | 11 | 13 | 16 | 42 | 145 | 378 | 0.0720 | 5.26 | 3.153 | 0.4465 | 52486.1 | 36900000 | 30400000000 | 27900000000000 | 0.5667 | 0.1091 | 0.0648 | 0.0042 | 0.2221 | 0.0305 | 0.2455 | 0.1491 | 0.1821 | 0.1574 | 0.1255 | 0.1533 | 0.0690 | 0.1678 | 0.0331 | 0.1262 | 0.0317 | 0.0846 | 0.0262 | 0.1269 | 0.0004 | 0.0000 | 0.0006 | 0.0006 | 0.0010 | 0.0017 | 0.0112 | 0.0092 | 0.0467 | 0.0430 | 0.0696 | 0.0628 | 0.0485 | 0.0415 | 0.0752 | 0.0685 | 0.7467 | 0.7729 | 0.0005 | 0.0005 | 0.0007 | 0.0007 | 0.0016 | 0.0025 | 0.0113 | 0.0152 | 0.0565 | 0.0539 | 0.0774 | 0.0786 | 0.0493 | 0.0607 | 0.0870 | 0.0851 | 0.7156 | 0.7027 | 0.0007 | 0.0000 | 0.0020 | 0.0119 | 0.0543 | 0.0701 | 0.0508 | 0.0795 | 0.7308 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 949 | 628 | | 5444 | 5921 | 503.2 | 113.35 | 118.69 | 220.33 | 340 | 443 | 485 | 510 | 528 | 546 | 564 | 585 | 614 | 0.1099 | 651 | 1.294 | 20.22 | 8.60 | 1 | 0.0103 | 56 | 0.0029 | 17.80 | 6.312 | 0.3065 | 266047.0 | 145000000 | 80700000000 | 45600000000000 | 0.4084 | 0.2255 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0074 | 0.0008 | 0.0372 | 0.0133 | 0.0597 | 0.0230 | 0.0638 | 0.0153 | 0.1089 | 0.0266 | 0.7193 | 0.9208 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0004 | 0.0158 | 0.0130 | 0.0270 | 0.0200 | 0.0203 | 0.0120 | 0.0363 | 0.0200 | 0.8999 | 0.9346 | 0.0097 | 0.0000 | 0.0110 | 0.0789 | 0.0331 | 0.1579 | 0.0607 | 0.0789 | 0.1062 | 0.1842 | 0.1407 | 0.1053 | 0.1407 | 0.0789 | 0.1434 | 0.2105 | 0.3545 | 0.1053 | 0.0000 | 0.0009 | 0.0035 | 0.0087 | 0.0363 | 0.0603 | 0.0609 | 0.0873 | 0.7421 | 7 | 10 | 14 | 19 | 25 | 37 | 74 | 153 | 375 | 0.0775 | 22.34 | 4.056 | 0.5583 | 62626.7 | 51300000 | 50500000000 | 55700000000000 | 0.5274 | 0.1314 | 0.0603 | 0.0015 | 0.2190 | 0.0164 | 0.3175 | 0.0848 | 0.1429 | 0.1711 | 0.1524 | 0.2321 | 0.0603 | 0.2292 | 0.0222 | 0.1295 | 0.0159 | 0.0744 | 0.0095 | 0.0610 | 0.0013 | 0.0006 | 0.0051 | 0.0011 | 0.0019 | 0.0033 | 0.0103 | 0.0094 | 0.0994 | 0.0833 | 0.1186 | 0.1127 | 0.0962 | 0.0944 | 0.1237 | 0.1133 | 0.5436 | 0.5819 | 0.0000 | 0.0009 | 0.0016 | 0.0009 | 0.0072 | 0.0071 | 0.0177 | 0.0301 | 0.1157 | 0.1125 | 0.1301 | 0.1364 | 0.1028 | 0.0912 | 0.1205 | 0.1355 | 0.5044 | 0.4854 | 0.0007 | 0.0007 | 0.0036 | 0.0144 | 0.1114 | 0.1222 | 0.0978 | 0.1258 | 0.5234 | ||
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 283 | 97 | | 3964 | 10522 | 352.2 | 81.30 | 461.34 | 382.37 | 252 | 288 | 313 | 334 | 354 | 372 | 392 | 416 | 452 | 0.0657 | 691 | 0.753 | 95.27 | 24.08 | 1 | 0.0658 | 261 | 0.0006 | 102.74 | 7.612 | 0.1258 | 130633.0 | 50600000 | 20400000000 | 8530000000000 | 0.4023 | 0.2386 | 0.0008 | 0.0000 | 0.0008 | 0.0000 | 0.0043 | 0.0000 | 0.0179 | 0.0014 | 0.0550 | 0.0209 | 0.1072 | 0.0390 | 0.1228 | 0.0329 | 0.1454 | 0.0549 | 0.5458 | 0.8510 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0061 | 0.0013 | 0.0223 | 0.0154 | 0.0444 | 0.0260 | 0.0471 | 0.0172 | 0.0640 | 0.0262 | 0.8145 | 0.9139 | 0.0000 | 0.0109 | 0.0100 | 0.0109 | 0.0242 | 0.0217 | 0.0627 | 0.1033 | 0.1296 | 0.1467 | 0.1553 | 0.1413 | 0.1254 | 0.1196 | 0.1538 | 0.1033 | 0.3390 | 0.3424 | 0.0010 | 0.0035 | 0.0049 | 0.0233 | 0.0673 | 0.1054 | 0.1049 | 0.1242 | 0.5656 | 46 | 92 | 175 | 276 | 376 | 494 | 622 | 777 | 1000 | 0.0020 | 93.98 | 7.546 | 0.2428 | 359026.0 | 355000000 | 407000000000 | 521000000000000 | 0.5626 | 0.1363 | 0.0068 | 0.0015 | 0.0542 | 0.0057 | 0.1423 | 0.0121 | 0.1725 | 0.0508 | 0.1725 | 0.1309 | 0.1744 | 0.1967 | 0.1072 | 0.1517 | 0.0930 | 0.1565 | 0.0770 | 0.2940 | 0.0004 | 0.0000 | 0.0039 | 0.0011 | 0.0049 | 0.0030 | 0.0161 | 0.0105 | 0.0447 | 0.0377 | 0.0709 | 0.0692 | 0.0629 | 0.0510 | 0.0765 | 0.0729 | 0.7196 | 0.7546 | 0.0008 | 0.0007 | 0.0027 | 0.0023 | 0.0065 | 0.0073 | 0.0220 | 0.0293 | 0.0578 | 0.0676 | 0.0957 | 0.1119 | 0.0774 | 0.0916 | 0.1013 | 0.1196 | 0.6358 | 0.5696 | 0.0002 | 0.0022 | 0.0038 | 0.0146 | 0.0510 | 0.0864 | 0.0649 | 0.0858 | 0.6910 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 609 | 251 | | 8474 | 32235 | 492.3 | 132.68 | 164.80 | 304.29 | 304 | 403 | 447 | 478 | 505 | 531 | 562 | 596 | 642 | 0.0423 | 1362 | 0.553 | 103.04 | 22.02 | 6 | 0.0340 | 288 | 0.0004 | 114.84 | 8.011 | 0.1304 | 259967.0 | 144000000 | 83000000000 | 49400000000000 | 0.3722 | 0.2591 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0037 | 0.0003 | 0.0143 | 0.0023 | 0.0499 | 0.0166 | 0.1100 | 0.0376 | 0.1112 | 0.0351 | 0.1452 | 0.0452 | 0.5648 | 0.8630 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0001 | 0.0025 | 0.0009 | 0.0146 | 0.0117 | 0.0325 | 0.0201 | 0.0307 | 0.0127 | 0.0470 | 0.0181 | 0.8723 | 0.9363 | 0.0022 | 0.0048 | 0.0077 | 0.0143 | 0.0132 | 0.0286 | 0.0548 | 0.0835 | 0.1064 | 0.2124 | 0.1656 | 0.1742 | 0.1162 | 0.1074 | 0.1436 | 0.1480 | 0.3904 | 0.2267 | 0.0004 | 0.0024 | 0.0034 | 0.0209 | 0.0482 | 0.0869 | 0.0897 | 0.1054 | 0.6428 | 11 | 14 | 16 | 19 | 25 | 41 | 97 | 243 | 543 | 0.1744 | 25.68 | 4.127 | 0.6433 | 119746.0 | 132000000 | 179000000000 | 274000000000000 | 0.3012 | 0.3397 | 0.0899 | 0.0040 | 0.2395 | 0.0218 | 0.2653 | 0.1374 | 0.1444 | 0.1732 | 0.1091 | 0.1910 | 0.0818 | 0.1739 | 0.0413 | 0.1102 | 0.0177 | 0.0848 | 0.0111 | 0.1039 | 0.0005 | 0.0004 | 0.0016 | 0.0005 | 0.0018 | 0.0022 | 0.0158 | 0.0127 | 0.0501 | 0.0477 | 0.0704 | 0.0633 | 0.0461 | 0.0432 | 0.0696 | 0.0655 | 0.7443 | 0.7646 | 0.0003 | 0.0003 | 0.0003 | 0.0026 | 0.0043 | 0.0048 | 0.0182 | 0.0201 | 0.0595 | 0.0574 | 0.0778 | 0.0868 | 0.0553 | 0.0575 | 0.0768 | 0.0805 | 0.7076 | 0.6901 | 0.0004 | 0.0001 | 0.0031 | 0.0149 | 0.0534 | 0.0785 | 0.0435 | 0.0762 | 0.7299 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 372 | 900 | | 5044 | 9324 | 570.5 | 98.09 | 110.30 | 193.81 | 423 | 504 | 548 | 574 | 591 | 608 | 625 | 644 | 675 | 0.0741 | 691 | 0.949 | 144.16 | 41.87 | 3 | 0.0765 | 386 | 0.0009 | 58.08 | 7.313 | 0.1858 | 335121.0 | 201000000 | 123000000000 | 76200000000000 | 0.4530 | 0.1918 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0002 | 0.0055 | 0.0012 | 0.0271 | 0.0139 | 0.0472 | 0.0212 | 0.0462 | 0.0133 | 0.0650 | 0.0234 | 0.8066 | 0.9268 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0018 | 0.0012 | 0.0148 | 0.0139 | 0.0237 | 0.0212 | 0.0189 | 0.0133 | 0.0283 | 0.0218 | 0.9121 | 0.9285 | 0.0051 | 1.0000 | 0.0204 | 0.0000 | 0.0382 | 0.0000 | 0.0789 | 0.0000 | 0.1399 | 0.0000 | 0.1527 | 0.0000 | 0.1425 | 0.0000 | 0.1552 | 0.0000 | 0.2672 | 0.0000 | 0.0006 | 0.0016 | 0.0039 | 0.0132 | 0.0319 | 0.0631 | 0.0673 | 0.0879 | 0.7304 | 13 | 15 | 17 | 20 | 24 | 37 | 65 | 143 | 347 | 0.2499 | 4.68 | 3.068 | 0.7533 | 49725.0 | 35000000 | 30000000000 | 29200000000000 | 0.6863 | 0.0611 | 0.0201 | 0.0070 | 0.0828 | 0.0120 | 0.2081 | 0.0468 | 0.1834 | 0.0807 | 0.1969 | 0.1723 | 0.1454 | 0.1912 | 0.0805 | 0.1524 | 0.0403 | 0.1404 | 0.0425 | 0.1972 | 0.0004 | 0.0022 | 0.0004 | 0.0022 | 0.0021 | 0.0065 | 0.0116 | 0.0151 | 0.0418 | 0.0391 | 0.0708 | 0.0613 | 0.0472 | 0.0459 | 0.0911 | 0.0911 | 0.7345 | 0.7368 | 0.0000 | 0.0006 | 0.0005 | 0.0006 | 0.0051 | 0.0011 | 0.0142 | 0.0146 | 0.0524 | 0.0611 | 0.0956 | 0.0952 | 0.0478 | 0.0538 | 0.0935 | 0.0947 | 0.6909 | 0.6784 | 0.0000 | 0.0000 | 0.0019 | 0.0116 | 0.0551 | 0.0811 | 0.0487 | 0.0982 | 0.7034 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1189 | 155 | | 5618 | 13253 | 344.2 | 70.32 | 104.68 | 99.98 | 259 | 282 | 300 | 316 | 333 | 354 | 379 | 407 | 444 | 0.0684 | 907 | 0.910 | 83.20 | 23.02 | 1 | 0.0377 | 212 | 0.0019 | 20.54 | 6.561 | 0.2353 | 123384.0 | 46000000 | 17900000000 | 7180000000000 | 0.3957 | 0.2470 | 0.0003 | 0.0000 | 0.0008 | 0.0002 | 0.0063 | 0.0002 | 0.0181 | 0.0011 | 0.0550 | 0.0161 | 0.1125 | 0.0345 | 0.1341 | 0.0319 | 0.1675 | 0.0521 | 0.5055 | 0.8638 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0032 | 0.0000 | 0.0071 | 0.0002 | 0.0199 | 0.0120 | 0.0402 | 0.0218 | 0.0557 | 0.0130 | 0.0771 | 0.0230 | 0.7960 | 0.9301 | 0.0029 | 0.0140 | 0.0069 | 0.0421 | 0.0255 | 0.0514 | 0.0609 | 0.1495 | 0.1159 | 0.1822 | 0.1906 | 0.1869 | 0.1375 | 0.1122 | 0.1503 | 0.1075 | 0.3094 | 0.1542 | 0.0020 | 0.0024 | 0.0071 | 0.0256 | 0.0643 | 0.1057 | 0.0923 | 0.1179 | 0.5826 | 14 | 27 | 43 | 59 | 75 | 94 | 119 | 159 | 237 | 0.0186 | 8.63 | 5.042 | 0.5074 | 20954.6 | 6170000 | 2290000000 | 982000000000 | 0.4377 | 0.2064 | 0.0105 | 0.0017 | 0.0659 | 0.0063 | 0.1467 | 0.0244 | 0.1714 | 0.0701 | 0.1841 | 0.1287 | 0.1586 | 0.1670 | 0.1270 | 0.1575 | 0.0857 | 0.1608 | 0.0501 | 0.2834 | 0.0010 | 0.0010 | 0.0042 | 0.0013 | 0.0055 | 0.0034 | 0.0205 | 0.0174 | 0.0627 | 0.0477 | 0.0920 | 0.0753 | 0.0818 | 0.0727 | 0.1040 | 0.0953 | 0.6284 | 0.6859 | 0.0011 | 0.0027 | 0.0038 | 0.0036 | 0.0089 | 0.0103 | 0.0277 | 0.0262 | 0.0728 | 0.0839 | 0.1098 | 0.1194 | 0.0899 | 0.0902 | 0.1106 | 0.1154 | 0.5756 | 0.5484 | 0.0011 | 0.0045 | 0.0087 | 0.0268 | 0.0665 | 0.1035 | 0.0854 | 0.1079 | 0.5957 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 792 | 805 | | 4919 | 8206 | 382.1 | 68.91 | 141.31 | 188.12 | 300 | 324 | 344 | 360 | 375 | 392 | 412 | 438 | 476 | 0.0898 | 737 | 1.029 | 141.51 | 47.89 | 1 | 0.0732 | 360 | 0.0011 | 37.46 | 7.089 | 0.1984 | 150764.0 | 61400000 | 25800000000 | 11200000000000 | 0.4301 | 0.2151 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0030 | 0.0000 | 0.0107 | 0.0015 | 0.0411 | 0.0153 | 0.0748 | 0.0283 | 0.0789 | 0.0233 | 0.1114 | 0.0344 | 0.6794 | 0.8971 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0041 | 0.0008 | 0.0202 | 0.0133 | 0.0357 | 0.0198 | 0.0359 | 0.0131 | 0.0538 | 0.0182 | 0.8484 | 0.9348 | 0.0014 | 0.0000 | 0.0043 | 0.0000 | 0.0216 | 0.0000 | 0.0620 | 0.0000 | 0.1037 | 0.0000 | 0.1527 | 0.0000 | 0.1081 | 0.0000 | 0.1326 | 0.0000 | 0.4135 | 0.0000 | 0.0022 | 0.0022 | 0.0118 | 0.0263 | 0.0679 | 0.1121 | 0.0937 | 0.1222 | 0.5617 | 17 | 22 | 29 | 36 | 53 | 94 | 149 | 244 | 370 | 0.0319 | 21.94 | 5.086 | 0.5347 | 55351.4 | 34100000 | 26500000000 | 23500000000000 | 0.4596 | 0.1622 | 0.0237 | 0.0014 | 0.1379 | 0.0121 | 0.2020 | 0.0752 | 0.1323 | 0.1079 | 0.1295 | 0.1526 | 0.1337 | 0.1923 | 0.0975 | 0.1214 | 0.0641 | 0.1008 | 0.0794 | 0.2363 | 0.0000 | 0.0000 | 0.0010 | 0.0003 | 0.0007 | 0.0012 | 0.0104 | 0.0064 | 0.0542 | 0.0436 | 0.0808 | 0.0753 | 0.0636 | 0.0516 | 0.0855 | 0.0680 | 0.7037 | 0.7537 | 0.0013 | 0.0000 | 0.0000 | 0.0010 | 0.0018 | 0.0015 | 0.0075 | 0.0185 | 0.0755 | 0.0713 | 0.1132 | 0.1307 | 0.0644 | 0.0723 | 0.1012 | 0.1142 | 0.6350 | 0.5905 | 0.0004 | 0.0008 | 0.0016 | 0.0117 | 0.0600 | 0.1028 | 0.0631 | 0.0919 | 0.6678 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 767 | 375 | | 10994 | 36702 | 317.2 | 66.33 | 88.78 | 117.60 | 238 | 259 | 276 | 292 | 309 | 327 | 346 | 373 | 410 | 0.0385 | 1412 | 0.777 | 113.02 | 23.02 | 1 | 0.0226 | 249 | 0.0006 | 70.27 | 7.726 | 0.1479 | 104984.0 | 36300000 | 13000000000 | 4880000000000 | 0.4228 | 0.2250 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0001 | 0.0125 | 0.0008 | 0.0612 | 0.0134 | 0.1259 | 0.0305 | 0.1295 | 0.0324 | 0.1666 | 0.0567 | 0.4994 | 0.8660 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0062 | 0.0003 | 0.0265 | 0.0088 | 0.0510 | 0.0177 | 0.0541 | 0.0124 | 0.0766 | 0.0239 | 0.7828 | 0.9370 | 0.0031 | 0.0102 | 0.0078 | 0.0225 | 0.0225 | 0.0758 | 0.0628 | 0.1250 | 0.1313 | 0.1557 | 0.1763 | 0.1475 | 0.1104 | 0.1025 | 0.1423 | 0.1270 | 0.3433 | 0.2336 | 0.0010 | 0.0030 | 0.0062 | 0.0294 | 0.0726 | 0.1184 | 0.1031 | 0.1345 | 0.5318 | 10 | 12 | 14 | 19 | 32 | 55 | 97 | 156 | 255 | 0.0788 | 13.52 | 4.639 | 0.5538 | 21712.5 | 8010000 | 3800000000 | 2180000000000 | 0.4103 | 0.2154 | 0.0637 | 0.0009 | 0.2390 | 0.0098 | 0.3525 | 0.1068 | 0.1643 | 0.1924 | 0.0959 | 0.2534 | 0.0480 | 0.2004 | 0.0216 | 0.1040 | 0.0113 | 0.0742 | 0.0037 | 0.0580 | 0.0002 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0012 | 0.0109 | 0.0097 | 0.0639 | 0.0507 | 0.0964 | 0.0843 | 0.0715 | 0.0616 | 0.1087 | 0.0931 | 0.6473 | 0.6989 | 0.0002 | 0.0004 | 0.0011 | 0.0016 | 0.0034 | 0.0043 | 0.0175 | 0.0189 | 0.0814 | 0.0927 | 0.1222 | 0.1338 | 0.0853 | 0.0887 | 0.1273 | 0.1253 | 0.5616 | 0.5343 | 0.0001 | 0.0004 | 0.0016 | 0.0110 | 0.0724 | 0.1147 | 0.0774 | 0.1169 | 0.6055 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1013 | 682 | | 13732 | 29163 | 489.2 | 88.51 | 64.45 | 140.69 | 369 | 416 | 448 | 471 | 492 | 513 | 535 | 561 | 598 | 0.0441 | 1286 | 0.817 | 91.92 | 19.24 | 13 | 0.0163 | 224 | 0.0009 | 42.91 | 7.350 | 0.2018 | 247158.0 | 129000000 | 68600000000 | 37500000000000 | 0.4764 | 0.1806 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0010 | 0.0002 | 0.0078 | 0.0008 | 0.0407 | 0.0122 | 0.0790 | 0.0262 | 0.0719 | 0.0181 | 0.1073 | 0.0285 | 0.6912 | 0.9139 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0001 | 0.0000 | 0.0022 | 0.0004 | 0.0199 | 0.0104 | 0.0412 | 0.0212 | 0.0321 | 0.0132 | 0.0499 | 0.0202 | 0.8544 | 0.9345 | 0.0040 | 0.0187 | 0.0103 | 0.0327 | 0.0343 | 0.0467 | 0.0623 | 0.0561 | 0.1189 | 0.1402 | 0.1320 | 0.2150 | 0.0971 | 0.1122 | 0.1223 | 0.1636 | 0.4189 | 0.2150 | 0.0010 | 0.0013 | 0.0046 | 0.0192 | 0.0608 | 0.1022 | 0.0895 | 0.1194 | 0.6020 | 6 | 7 | 9 | 10 | 11 | 13 | 21 | 61 | 192 | 0.2959 | 12.61 | 3.087 | 0.7489 | 23946.5 | 14200000 | 10300000000 | 8680000000000 | 0.5403 | 0.1285 | 0.0409 | 0.0032 | 0.1110 | 0.0290 | 0.1519 | 0.0767 | 0.1548 | 0.0965 | 0.1500 | 0.1282 | 0.1519 | 0.1650 | 0.1042 | 0.1195 | 0.0828 | 0.1232 | 0.0526 | 0.2587 | 0.0003 | 0.0007 | 0.0006 | 0.0010 | 0.0021 | 0.0026 | 0.0106 | 0.0112 | 0.0421 | 0.0350 | 0.0683 | 0.0631 | 0.0405 | 0.0400 | 0.0644 | 0.0618 | 0.7712 | 0.7846 | 0.0002 | 0.0000 | 0.0013 | 0.0008 | 0.0025 | 0.0025 | 0.0115 | 0.0135 | 0.0507 | 0.0532 | 0.0788 | 0.0824 | 0.0465 | 0.0475 | 0.0710 | 0.0731 | 0.7375 | 0.7270 | 0.0007 | 0.0010 | 0.0017 | 0.0150 | 0.0416 | 0.0733 | 0.0472 | 0.0663 | 0.7529 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1161 | 623 | | 4896 | 12890 | 292.1 | 122.93 | 77.58 | 156.83 | 140 | 170 | 195 | 234 | 275 | 322 | 378 | 426 | 471 | 0.0714 | 920 | 0.771 | 63.56 | 16.03 | 4 | 0.0327 | 160 | 0.0010 | 16.01 | 7.132 | 0.2695 | 100453.0 | 38700000 | 16000000000 | 6940000000000 | 0.3486 | 0.2680 | 0.0008 | 0.0004 | 0.0008 | 0.0015 | 0.0008 | 0.0030 | 0.0194 | 0.0109 | 0.0891 | 0.0449 | 0.1336 | 0.0612 | 0.1263 | 0.0581 | 0.1571 | 0.0849 | 0.4721 | 0.7350 | 0.0003 | 0.0000 | 0.0003 | 0.0003 | 0.0003 | 0.0018 | 0.0061 | 0.0047 | 0.0187 | 0.0171 | 0.0224 | 0.0237 | 0.0252 | 0.0179 | 0.0330 | 0.0339 | 0.8936 | 0.9006 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0035 | 0.0053 | 0.0087 | 0.0381 | 0.0582 | 0.0545 | 0.0582 | 0.0393 | 0.0616 | 0.0527 | 0.0851 | 0.8102 | 0.7240 | 0.0000 | 0.0004 | 0.0009 | 0.0035 | 0.0274 | 0.0363 | 0.0314 | 0.0456 | 0.8544 | 7 | 9 | 11 | 13 | 17 | 25 | 42 | 84 | 223 | 0.1061 | 17.09 | 3.929 | 0.6640 | 30613.2 | 21000000 | 18400000000 | 18500000000000 | 0.3956 | 0.2278 | 0.0335 | 0.0066 | 0.0911 | 0.0183 | 0.1580 | 0.0374 | 0.2026 | 0.0682 | 0.2286 | 0.1364 | 0.1283 | 0.1540 | 0.1022 | 0.1393 | 0.0353 | 0.1598 | 0.0204 | 0.2801 | 0.0027 | 0.0025 | 0.0047 | 0.0030 | 0.0047 | 0.0050 | 0.0097 | 0.0116 | 0.0484 | 0.0449 | 0.0684 | 0.0581 | 0.0494 | 0.0512 | 0.0735 | 0.0722 | 0.7386 | 0.7516 | 0.0004 | 0.0009 | 0.0004 | 0.0004 | 0.0033 | 0.0035 | 0.0114 | 0.0097 | 0.0521 | 0.0578 | 0.0720 | 0.0843 | 0.0606 | 0.0618 | 0.0781 | 0.0856 | 0.7216 | 0.6961 | 0.0004 | 0.0011 | 0.0026 | 0.0086 | 0.0474 | 0.0784 | 0.0523 | 0.0732 | 0.7359 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 780 | 643 | | 4246 | 9503 | 153.2 | 43.23 | 163.95 | 111.35 | 107 | 118 | 127 | 135 | 144 | 155 | 167 | 184 | 213 | 0.0930 | 884 | 1.215 | 66.84 | 30.36 | 1 | 0.0445 | 189 | 0.0016 | 33.38 | 6.721 | 0.2068 | 25324.3 | 4540000 | 884000000 | 186000000000 | 0.4222 | 0.2177 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0065 | 0.0005 | 0.0285 | 0.0037 | 0.1085 | 0.0264 | 0.1876 | 0.0650 | 0.1746 | 0.0647 | 0.2040 | 0.0836 | 0.2891 | 0.7561 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0110 | 0.0012 | 0.0397 | 0.0171 | 0.0784 | 0.0293 | 0.0800 | 0.0238 | 0.1178 | 0.0358 | 0.6711 | 0.8927 | 0.0023 | 0.0000 | 0.0047 | 0.0049 | 0.0140 | 0.0196 | 0.0756 | 0.1225 | 0.1465 | 0.1716 | 0.1686 | 0.2059 | 0.1128 | 0.1152 | 0.1419 | 0.1127 | 0.3337 | 0.2475 | 0.0011 | 0.0022 | 0.0056 | 0.0332 | 0.0917 | 0.1507 | 0.1074 | 0.1277 | 0.4803 | 49 | 74 | 95 | 116 | 139 | 164 | 198 | 245 | 310 | 0.0019 | 44.15 | 6.783 | 0.2632 | 39278.6 | 12800000 | 5480000000 | 3000000000000 | 0.5562 | 0.1215 | 0.0241 | 0.0012 | 0.0805 | 0.0056 | 0.1411 | 0.0391 | 0.1416 | 0.0770 | 0.1754 | 0.1299 | 0.1546 | 0.1697 | 0.1157 | 0.1456 | 0.0995 | 0.1528 | 0.0676 | 0.2792 | 0.0014 | 0.0002 | 0.0026 | 0.0009 | 0.0069 | 0.0057 | 0.0242 | 0.0137 | 0.0746 | 0.0545 | 0.1063 | 0.0876 | 0.0950 | 0.0778 | 0.1295 | 0.1115 | 0.5595 | 0.6480 | 0.0031 | 0.0018 | 0.0045 | 0.0054 | 0.0118 | 0.0145 | 0.0478 | 0.0559 | 0.1069 | 0.1335 | 0.1491 | 0.1807 | 0.1301 | 0.1326 | 0.1557 | 0.1685 | 0.3910 | 0.3070 | 0.0018 | 0.0050 | 0.0089 | 0.0404 | 0.0908 | 0.1409 | 0.1049 | 0.1375 | 0.4699 |