High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1270 | 935 | | 2332 | 2784 | 77.0 | 17.41 | 147.31 | 171.19 | 57 | 63 | 67 | 71 | 75 | 79 | 84 | 90 | 98 | 0.1566 | 436 | 0.850 | 77.94 | 29.70 | 1 | 0.1038 | 242 | 0.0063 | 9.67 | 5.383 | 0.3501 | 6226.1 | 531430 | 48100000 | 4640000000 | 0.4627 | 0.1874 | 0.0013 | 0.0000 | 0.0038 | 0.0005 | 0.0089 | 0.0014 | 0.0335 | 0.0046 | 0.0772 | 0.0246 | 0.1392 | 0.0483 | 0.1512 | 0.0433 | 0.1980 | 0.0724 | 0.3871 | 0.8050 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0031 | 0.0000 | 0.0098 | 0.0013 | 0.0411 | 0.0183 | 0.0878 | 0.0404 | 0.0734 | 0.0243 | 0.1145 | 0.0469 | 0.6689 | 0.8688 | 0.0109 | 0.0189 | 0.0327 | 0.0189 | 0.0463 | 0.0566 | 0.1308 | 0.1509 | 0.1417 | 0.1887 | 0.1989 | 0.2264 | 0.1144 | 0.0943 | 0.1608 | 0.1321 | 0.1635 | 0.1132 | 0.0028 | 0.0123 | 0.0274 | 0.0482 | 0.1154 | 0.1703 | 0.1060 | 0.1552 | 0.3623 | 13 | 16 | 21 | 34 | 74 | 129 | 190 | 273 | 377 | 0.0284 | 57.62 | 5.532 | 0.4008 | 50997.4 | 24600000 | 14500000000 | 9660000000000 | 0.5052 | 0.1542 | 0.0789 | 0.0074 | 0.2366 | 0.0391 | 0.2258 | 0.1657 | 0.1075 | 0.1304 | 0.1004 | 0.1657 | 0.1183 | 0.1657 | 0.0824 | 0.1229 | 0.0323 | 0.0838 | 0.0179 | 0.1192 | 0.0017 | 0.0000 | 0.0017 | 0.0008 | 0.0051 | 0.0084 | 0.0146 | 0.0114 | 0.0788 | 0.0729 | 0.1311 | 0.1109 | 0.0874 | 0.0858 | 0.1482 | 0.1291 | 0.5313 | 0.5809 | 0.0011 | 0.0000 | 0.0045 | 0.0064 | 0.0124 | 0.0141 | 0.0236 | 0.0295 | 0.1025 | 0.1013 | 0.1577 | 0.1782 | 0.1092 | 0.1115 | 0.1441 | 0.1449 | 0.4448 | 0.4141 | 0.0020 | 0.0039 | 0.0039 | 0.0225 | 0.1000 | 0.1324 | 0.1049 | 0.1471 | 0.4833 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 730 | 546 | | 7063 | 16463 | 184.9 | 40.76 | 99.35 | 87.89 | 137 | 151 | 161 | 169 | 179 | 190 | 202 | 219 | 240 | 0.0580 | 955 | 0.941 | 64.47 | 21.02 | 1 | 0.0239 | 169 | 0.0014 | 32.05 | 6.883 | 0.2025 | 35864.6 | 7300000 | 1560000000 | 348000000000 | 0.4301 | 0.2260 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0035 | 0.0000 | 0.0175 | 0.0003 | 0.0785 | 0.0161 | 0.1523 | 0.0437 | 0.1574 | 0.0461 | 0.1936 | 0.0763 | 0.3963 | 0.8174 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0067 | 0.0003 | 0.0317 | 0.0110 | 0.0693 | 0.0226 | 0.0664 | 0.0177 | 0.0909 | 0.0300 | 0.7338 | 0.9185 | 0.0054 | 0.0134 | 0.0069 | 0.0214 | 0.0239 | 0.0456 | 0.0677 | 0.1877 | 0.1524 | 0.2091 | 0.1963 | 0.1743 | 0.1301 | 0.1072 | 0.1617 | 0.1099 | 0.2556 | 0.1314 | 0.0009 | 0.0041 | 0.0135 | 0.0340 | 0.0810 | 0.1216 | 0.1141 | 0.1377 | 0.4931 | 13 | 22 | 36 | 53 | 73 | 98 | 131 | 169 | 224 | 0.0086 | 26.48 | 6.137 | 0.3816 | 17595.6 | 4190000 | 1210000000 | 411000000000 | 0.4596 | 0.1971 | 0.0237 | 0.0019 | 0.1194 | 0.0081 | 0.2469 | 0.0504 | 0.1843 | 0.1053 | 0.1708 | 0.1723 | 0.1252 | 0.1953 | 0.0725 | 0.1462 | 0.0367 | 0.1457 | 0.0206 | 0.1747 | 0.0004 | 0.0003 | 0.0021 | 0.0017 | 0.0031 | 0.0027 | 0.0125 | 0.0104 | 0.0556 | 0.0435 | 0.0954 | 0.0686 | 0.0762 | 0.0660 | 0.1107 | 0.0934 | 0.6440 | 0.7133 | 0.0004 | 0.0007 | 0.0015 | 0.0031 | 0.0060 | 0.0094 | 0.0218 | 0.0307 | 0.0828 | 0.1016 | 0.1359 | 0.1542 | 0.1068 | 0.1143 | 0.1359 | 0.1477 | 0.5090 | 0.4384 | 0.0005 | 0.0005 | 0.0038 | 0.0189 | 0.0670 | 0.1146 | 0.0919 | 0.1238 | 0.5791 | ||
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 919 | 900 | | 2948 | 8244 | 666.3 | 129.72 | 46.17 | 98.68 | 485 | 545 | 590 | 628 | 667 | 705 | 744 | 787 | 840 | 0.0761 | 627 | 1.113 | 69.64 | 24.02 | 1 | 0.0580 | 171 | 0.0007 | 51.40 | 7.349 | 0.1601 | 460748.0 | 329000000 | 243000000000 | 184000000000000 | 0.3935 | 0.2423 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0016 | 0.0000 | 0.0110 | 0.0014 | 0.0460 | 0.0183 | 0.0826 | 0.0341 | 0.0727 | 0.0251 | 0.1130 | 0.0389 | 0.6715 | 0.8822 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0041 | 0.0007 | 0.0202 | 0.0156 | 0.0326 | 0.0302 | 0.0223 | 0.0156 | 0.0396 | 0.0282 | 0.8808 | 0.9097 | 0.0019 | 0.0000 | 0.0039 | 0.0476 | 0.0273 | 0.0476 | 0.0253 | 0.1905 | 0.0916 | 0.2857 | 0.1443 | 0.1190 | 0.1033 | 0.2381 | 0.1618 | 0.0714 | 0.4405 | 0.0000 | 0.0007 | 0.0007 | 0.0027 | 0.0115 | 0.0392 | 0.0635 | 0.0581 | 0.0878 | 0.7360 | 9 | 11 | 12 | 14 | 16 | 21 | 28 | 43 | 87 | 0.1378 | 4.69 | 3.060 | 0.7458 | 11867.4 | 6550000 | 4590000000 | 3630000000000 | 0.6519 | 0.0809 | 0.0058 | 0.0114 | 0.0378 | 0.0178 | 0.0683 | 0.0242 | 0.1541 | 0.0604 | 0.1788 | 0.0768 | 0.1788 | 0.1230 | 0.1541 | 0.1393 | 0.1424 | 0.1628 | 0.0799 | 0.3845 | 0.0010 | 0.0064 | 0.0066 | 0.0092 | 0.0082 | 0.0104 | 0.0255 | 0.0249 | 0.0541 | 0.0385 | 0.0745 | 0.0686 | 0.0760 | 0.0735 | 0.1102 | 0.0951 | 0.6439 | 0.6732 | 0.0008 | 0.0018 | 0.0063 | 0.0055 | 0.0181 | 0.0101 | 0.0291 | 0.0194 | 0.0708 | 0.0738 | 0.0904 | 0.1042 | 0.0818 | 0.0821 | 0.1344 | 0.1245 | 0.5684 | 0.5784 | 0.0032 | 0.0051 | 0.0154 | 0.0199 | 0.0656 | 0.0836 | 0.0855 | 0.1215 | 0.6000 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1169 | 718 | | 3803 | 6960 | 84.4 | 20.56 | 84.20 | 75.35 | 60 | 68 | 73 | 77 | 82 | 88 | 94 | 101 | 111 | 0.1295 | 901 | 1.055 | 100.65 | 36.80 | 3 | 0.0702 | 267 | 0.0048 | 9.98 | 5.662 | 0.3488 | 7539.7 | 712809 | 71300000 | 7550000000 | 0.4461 | 0.2010 | 0.0035 | 0.0000 | 0.0035 | 0.0006 | 0.0133 | 0.0014 | 0.0434 | 0.0049 | 0.1018 | 0.0301 | 0.1540 | 0.0703 | 0.1717 | 0.0627 | 0.1965 | 0.1162 | 0.3124 | 0.7138 | 0.0007 | 0.0000 | 0.0013 | 0.0003 | 0.0026 | 0.0008 | 0.0141 | 0.0025 | 0.0434 | 0.0234 | 0.0736 | 0.0485 | 0.0696 | 0.0294 | 0.0923 | 0.0539 | 0.7024 | 0.8412 | 0.0038 | 0.0423 | 0.0153 | 0.0329 | 0.0204 | 0.0798 | 0.1008 | 0.1596 | 0.1288 | 0.1831 | 0.1760 | 0.2019 | 0.1492 | 0.1221 | 0.1620 | 0.0845 | 0.2436 | 0.0939 | 0.0016 | 0.0066 | 0.0131 | 0.0334 | 0.0826 | 0.1067 | 0.1100 | 0.1379 | 0.5082 | 21 | 29 | 36 | 45 | 57 | 72 | 93 | 129 | 196 | 0.0215 | 6.08 | 4.792 | 0.5469 | 12767.1 | 2810000 | 768000000 | 242000000000 | 0.5949 | 0.1190 | 0.0236 | 0.0027 | 0.0754 | 0.0155 | 0.1471 | 0.0354 | 0.1680 | 0.0787 | 0.1916 | 0.1437 | 0.1471 | 0.1641 | 0.1235 | 0.1433 | 0.0836 | 0.1636 | 0.0400 | 0.2530 | 0.0027 | 0.0010 | 0.0061 | 0.0052 | 0.0097 | 0.0081 | 0.0289 | 0.0240 | 0.0729 | 0.0672 | 0.1069 | 0.0930 | 0.0901 | 0.0750 | 0.1103 | 0.1066 | 0.5724 | 0.6198 | 0.0048 | 0.0038 | 0.0112 | 0.0038 | 0.0117 | 0.0102 | 0.0363 | 0.0326 | 0.0811 | 0.0856 | 0.1323 | 0.1475 | 0.0961 | 0.0958 | 0.1126 | 0.1315 | 0.5139 | 0.4891 | 0.0013 | 0.0093 | 0.0160 | 0.0388 | 0.0835 | 0.1210 | 0.0923 | 0.1151 | 0.5228 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 992 | 554 | | 458 | 453 | 58.6 | 18.24 | 15.98 | 3.18 | 38 | 42 | 46 | 52 | 56 | 61 | 66 | 72 | 84 | 0.4040 | 183 | 0.735 | 110.07 | 27.07 | 1 | 0.6135 | 281 | 0.0119 | 5.25 | 4.713 | 0.4351 | 3769.0 | 265175 | 20300000 | 1680000000 | 0.3546 | 0.2594 | 0.0000 | 0.0000 | 0.0199 | 0.0000 | 0.0448 | 0.0000 | 0.0597 | 0.0052 | 0.1294 | 0.0735 | 0.2139 | 0.1417 | 0.1791 | 0.0761 | 0.1343 | 0.1155 | 0.2189 | 0.5879 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0164 | 0.0046 | 0.0656 | 0.0371 | 0.1049 | 0.0928 | 0.0721 | 0.0278 | 0.0951 | 0.0603 | 0.6459 | 0.7773 | 0.0096 | 0.0000 | 0.0000 | 0.0000 | 0.0096 | 0.0600 | 0.0673 | 0.1800 | 0.2019 | 0.1000 | 0.1731 | 0.2800 | 0.0865 | 0.1400 | 0.1635 | 0.0600 | 0.2885 | 0.1800 | 0.0000 | 0.0000 | 0.0048 | 0.0335 | 0.1435 | 0.1483 | 0.1100 | 0.1627 | 0.3971 | 12 | 13 | 14 | 15 | 16 | 17 | 17 | 18 | 20 | 0.8738 | 0.06 | 0.306 | 0.9702 | 265.5 | 4574.87 | 81636.7 | 1510000 | 0.5349 | 0.1049 | 0.0031 | 0.0000 | 0.0217 | 0.0000 | 0.0683 | 0.0046 | 0.1211 | 0.0207 | 0.2050 | 0.1359 | 0.1739 | 0.1544 | 0.1739 | 0.1613 | 0.1801 | 0.1521 | 0.0528 | 0.3710 | 0.0026 | 0.0000 | 0.0078 | 0.0000 | 0.0284 | 0.0045 | 0.0413 | 0.0089 | 0.1835 | 0.1250 | 0.1550 | 0.1473 | 0.1576 | 0.1518 | 0.1938 | 0.1384 | 0.2300 | 0.4241 | 0.2923 | 0.5000 | 0.1846 | 0.2143 | 0.1385 | 0.2143 | 0.1846 | 0.0714 | 0.1077 | 0.0000 | 0.0615 | 0.0000 | 0.0308 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0586 | 0.1328 | 0.1445 | 0.1758 | 0.1680 | 0.1367 | 0.1055 | 0.0586 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 931 | 115 | | 3279 | 6983 | 116.8 | 25.16 | 91.19 | 65.40 | 87 | 94 | 101 | 107 | 114 | 121 | 129 | 138 | 151 | 0.0971 | 678 | 0.521 | 85.63 | 18.00 | 1 | 0.0753 | 247 | 0.0015 | 34.98 | 6.738 | 0.2061 | 14263.7 | 1820000 | 243000000 | 33600000000 | 0.4567 | 0.1958 | 0.0015 | 0.0000 | 0.0044 | 0.0000 | 0.0174 | 0.0003 | 0.0377 | 0.0055 | 0.0856 | 0.0281 | 0.1393 | 0.0445 | 0.1581 | 0.0448 | 0.1978 | 0.0726 | 0.3583 | 0.8042 | 0.0011 | 0.0000 | 0.0026 | 0.0000 | 0.0049 | 0.0003 | 0.0098 | 0.0003 | 0.0448 | 0.0203 | 0.0726 | 0.0276 | 0.0704 | 0.0218 | 0.1099 | 0.0470 | 0.6839 | 0.8827 | 0.0068 | 0.0000 | 0.0102 | 0.0382 | 0.0441 | 0.0892 | 0.0849 | 0.1401 | 0.1494 | 0.2038 | 0.1511 | 0.1975 | 0.1324 | 0.1592 | 0.1647 | 0.0701 | 0.2564 | 0.1019 | 0.0026 | 0.0072 | 0.0132 | 0.0349 | 0.0829 | 0.1250 | 0.0980 | 0.1342 | 0.5020 | 26 | 35 | 46 | 59 | 74 | 91 | 112 | 140 | 183 | 0.0140 | 7.49 | 5.001 | 0.4623 | 12591.6 | 2290000 | 504000000 | 127000000000 | 0.5517 | 0.1402 | 0.0219 | 0.0015 | 0.1015 | 0.0080 | 0.1790 | 0.0298 | 0.2075 | 0.0795 | 0.2009 | 0.1677 | 0.1286 | 0.2109 | 0.0825 | 0.1702 | 0.0475 | 0.1583 | 0.0307 | 0.1742 | 0.0011 | 0.0005 | 0.0025 | 0.0032 | 0.0070 | 0.0029 | 0.0242 | 0.0174 | 0.0752 | 0.0594 | 0.1144 | 0.0807 | 0.1014 | 0.0818 | 0.1355 | 0.1148 | 0.5386 | 0.6392 | 0.0009 | 0.0042 | 0.0060 | 0.0072 | 0.0133 | 0.0240 | 0.0486 | 0.0665 | 0.1298 | 0.1450 | 0.1660 | 0.1905 | 0.1243 | 0.1240 | 0.1596 | 0.1534 | 0.3517 | 0.2852 | 0.0021 | 0.0046 | 0.0099 | 0.0368 | 0.0916 | 0.1561 | 0.1164 | 0.1465 | 0.4360 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 461 | 123 | | 3257 | 6809 | 514.7 | 105.53 | 61.25 | 124.20 | 368 | 433 | 474 | 500 | 525 | 551 | 579 | 608 | 638 | 0.0824 | 561 | 0.766 | 87.00 | 16.03 | 3 | 0.0620 | 202 | 0.0010 | 52.75 | 7.148 | 0.1825 | 276060.0 | 153000000 | 86800000000 | 50400000000000 | 0.4286 | 0.2196 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0068 | 0.0000 | 0.0140 | 0.0013 | 0.0512 | 0.0198 | 0.0978 | 0.0406 | 0.0965 | 0.0227 | 0.1277 | 0.0373 | 0.6046 | 0.8782 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0029 | 0.0013 | 0.0220 | 0.0197 | 0.0447 | 0.0384 | 0.0293 | 0.0184 | 0.0411 | 0.0288 | 0.8596 | 0.8934 | 0.0077 | 0.1333 | 0.0173 | 0.1333 | 0.0288 | 0.0667 | 0.0865 | 0.1333 | 0.1404 | 0.2667 | 0.1442 | 0.1333 | 0.1231 | 0.0000 | 0.1654 | 0.1333 | 0.2865 | 0.0000 | 0.0011 | 0.0023 | 0.0079 | 0.0186 | 0.0514 | 0.0814 | 0.0729 | 0.1040 | 0.6605 | 7 | 9 | 11 | 12 | 14 | 19 | 31 | 56 | 175 | 0.1883 | 7.43 | 3.201 | 0.7374 | 19174.6 | 10600000 | 7360000000 | 5780000000000 | 0.4921 | 0.1647 | 0.0338 | 0.0142 | 0.0549 | 0.0252 | 0.0717 | 0.0377 | 0.0928 | 0.0660 | 0.1392 | 0.0849 | 0.1814 | 0.1289 | 0.2363 | 0.1321 | 0.1097 | 0.1525 | 0.0802 | 0.3585 | 0.0034 | 0.0045 | 0.0048 | 0.0078 | 0.0034 | 0.0111 | 0.0109 | 0.0167 | 0.0212 | 0.0279 | 0.0519 | 0.0507 | 0.0355 | 0.0423 | 0.0444 | 0.0591 | 0.8245 | 0.7799 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0016 | 0.0000 | 0.0073 | 0.0078 | 0.0334 | 0.0336 | 0.0465 | 0.0509 | 0.0302 | 0.0259 | 0.0522 | 0.0578 | 0.8280 | 0.8240 | 0.0008 | 0.0008 | 0.0046 | 0.0106 | 0.0236 | 0.0540 | 0.0274 | 0.0547 | 0.8237 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1110 | 560 | | 2334 | 4086 | 123.1 | 42.05 | 219.05 | 128.32 | 74 | 87 | 96 | 107 | 117 | 129 | 142 | 157 | 183 | 0.1216 | 497 | 1.080 | 108.23 | 35.38 | 1 | 0.1204 | 281 | 0.0009 | 90.87 | 7.214 | 0.1270 | 16914.4 | 2570000 | 424000000 | 75500000000 | 0.4870 | 0.1611 | 0.0000 | 0.0000 | 0.0062 | 0.0006 | 0.0503 | 0.0006 | 0.1077 | 0.0083 | 0.1877 | 0.0598 | 0.2236 | 0.1374 | 0.1549 | 0.1291 | 0.1251 | 0.1551 | 0.1446 | 0.5091 | 0.0000 | 0.0000 | 0.0013 | 0.0005 | 0.0013 | 0.0000 | 0.0139 | 0.0057 | 0.0606 | 0.0335 | 0.1205 | 0.0746 | 0.0833 | 0.0581 | 0.1091 | 0.0846 | 0.6101 | 0.7430 | 0.0016 | 0.0000 | 0.0049 | 0.0000 | 0.0148 | 0.0256 | 0.0590 | 0.1026 | 0.1426 | 0.1891 | 0.1672 | 0.1987 | 0.1344 | 0.1218 | 0.1656 | 0.1346 | 0.3098 | 0.2276 | 0.0000 | 0.0019 | 0.0104 | 0.0321 | 0.0888 | 0.1671 | 0.1048 | 0.1398 | 0.4551 | 74 | 103 | 134 | 163 | 195 | 230 | 276 | 327 | 396 | 0.0027 | 23.43 | 6.329 | 0.2976 | 64441.3 | 23200000 | 9650000000 | 4520000000000 | 0.5232 | 0.1346 | 0.0093 | 0.0010 | 0.0558 | 0.0031 | 0.1767 | 0.0135 | 0.1787 | 0.0556 | 0.1911 | 0.1329 | 0.1560 | 0.1989 | 0.1188 | 0.1848 | 0.0692 | 0.1776 | 0.0444 | 0.2326 | 0.0004 | 0.0003 | 0.0009 | 0.0007 | 0.0044 | 0.0031 | 0.0126 | 0.0097 | 0.0566 | 0.0384 | 0.1111 | 0.0746 | 0.0910 | 0.0695 | 0.1324 | 0.1126 | 0.5906 | 0.6911 | 0.0015 | 0.0041 | 0.0068 | 0.0021 | 0.0090 | 0.0155 | 0.0384 | 0.0671 | 0.1032 | 0.1405 | 0.1800 | 0.1736 | 0.1122 | 0.1395 | 0.1611 | 0.1736 | 0.3878 | 0.2841 | 0.0000 | 0.0023 | 0.0051 | 0.0277 | 0.0779 | 0.1429 | 0.1107 | 0.1440 | 0.4896 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 387 | 777 | | 3566 | 6931 | 639.4 | 107.04 | 10.06 | 4.66 | 486 | 547 | 588 | 620 | 651 | 674 | 700 | 732 | 773 | 0.0884 | 613 | 1.124 | 98.72 | 31.38 | 1 | 0.0670 | 239 | 0.0010 | 36.61 | 7.121 | 0.1989 | 420338.0 | 283000000 | 195000000000 | 137000000000000 | 0.3984 | 0.2382 | 0.0011 | 0.0000 | 0.0011 | 0.0000 | 0.0053 | 0.0000 | 0.0083 | 0.0003 | 0.0320 | 0.0164 | 0.0531 | 0.0288 | 0.0531 | 0.0164 | 0.0753 | 0.0257 | 0.7708 | 0.9124 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0029 | 0.0003 | 0.0186 | 0.0158 | 0.0258 | 0.0270 | 0.0225 | 0.0141 | 0.0287 | 0.0217 | 0.9000 | 0.9211 | 0.0000 | 0.0000 | 0.0149 | 0.1667 | 0.0446 | 0.0833 | 0.0718 | 0.2500 | 0.0767 | 0.2500 | 0.1287 | 0.2500 | 0.0965 | 0.0000 | 0.1658 | 0.0000 | 0.4010 | 0.0000 | 0.0010 | 0.0005 | 0.0021 | 0.0124 | 0.0361 | 0.0465 | 0.0589 | 0.0780 | 0.7646 | 5 | 7 | 7 | 8 | 9 | 10 | 12 | 13 | 16 | 0.4127 | 0.30 | 1.079 | 0.7896 | 122.9 | 1790.87 | 30353.2 | 582290 | 0.5361 | 0.1291 | 0.0335 | 0.0045 | 0.0959 | 0.0139 | 0.1633 | 0.0252 | 0.2000 | 0.0536 | 0.2138 | 0.0902 | 0.1661 | 0.1532 | 0.0951 | 0.2086 | 0.0264 | 0.2648 | 0.0059 | 0.1859 | 0.0097 | 0.0003 | 0.0311 | 0.0027 | 0.0593 | 0.0058 | 0.0757 | 0.0236 | 0.0929 | 0.0587 | 0.1048 | 0.1040 | 0.1018 | 0.1321 | 0.1193 | 0.1860 | 0.4054 | 0.4869 | 0.0652 | 0.0615 | 0.0666 | 0.0608 | 0.0576 | 0.0615 | 0.0566 | 0.0660 | 0.0756 | 0.0801 | 0.0809 | 0.1008 | 0.0856 | 0.1127 | 0.1365 | 0.1579 | 0.3754 | 0.2987 | 0.0501 | 0.0714 | 0.0772 | 0.0740 | 0.0778 | 0.0730 | 0.0804 | 0.1126 | 0.3836 | ||
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 504 | 454 | | 4632 | 9949 | 526.7 | 103.94 | 144.23 | 161.03 | 403 | 434 | 461 | 488 | 517 | 541 | 573 | 613 | 674 | 0.0767 | 763 | 1.167 | 101.13 | 34.54 | 1 | 0.0531 | 246 | 0.0009 | 55.30 | 7.231 | 0.1624 | 288245.0 | 164000000 | 96700000000 | 59100000000000 | 0.4365 | 0.2052 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0095 | 0.0004 | 0.0653 | 0.0181 | 0.1242 | 0.0349 | 0.1378 | 0.0329 | 0.1714 | 0.0511 | 0.4897 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0044 | 0.0002 | 0.0279 | 0.0136 | 0.0541 | 0.0242 | 0.0597 | 0.0141 | 0.0859 | 0.0249 | 0.7668 | 0.9230 | 0.0054 | 0.0188 | 0.0054 | 0.0125 | 0.0201 | 0.0313 | 0.0698 | 0.1438 | 0.1557 | 0.2438 | 0.1906 | 0.1750 | 0.1302 | 0.1188 | 0.1664 | 0.1563 | 0.2564 | 0.1000 | 0.0009 | 0.0038 | 0.0033 | 0.0302 | 0.0797 | 0.1282 | 0.1249 | 0.1556 | 0.4734 | 18 | 28 | 46 | 67 | 93 | 124 | 163 | 220 | 330 | 0.0156 | 19.65 | 5.459 | 0.4608 | 46729.0 | 24700000 | 17300000000 | 14400000000000 | 0.5530 | 0.1302 | 0.0176 | 0.0010 | 0.1067 | 0.0100 | 0.2360 | 0.0424 | 0.1854 | 0.0883 | 0.1601 | 0.1621 | 0.1292 | 0.2014 | 0.0730 | 0.1717 | 0.0597 | 0.1438 | 0.0323 | 0.1793 | 0.0002 | 0.0000 | 0.0009 | 0.0012 | 0.0024 | 0.0019 | 0.0176 | 0.0129 | 0.0691 | 0.0574 | 0.1203 | 0.0945 | 0.0888 | 0.0781 | 0.1108 | 0.1107 | 0.5899 | 0.6432 | 0.0004 | 0.0009 | 0.0011 | 0.0022 | 0.0061 | 0.0106 | 0.0301 | 0.0396 | 0.1050 | 0.1091 | 0.1384 | 0.1552 | 0.0986 | 0.0994 | 0.1376 | 0.1271 | 0.4828 | 0.4560 | 0.0017 | 0.0012 | 0.0043 | 0.0240 | 0.0822 | 0.1343 | 0.0909 | 0.1308 | 0.5305 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 141 | 279 | | 6550 | 28560 | 325.2 | 76.94 | 118.00 | 205.38 | 229 | 259 | 281 | 299 | 318 | 339 | 361 | 391 | 431 | 0.0380 | 1086 | 1.019 | 88.10 | 26.68 | 3 | 0.0337 | 221 | 0.0007 | 63.80 | 7.487 | 0.1467 | 111704.0 | 40400000 | 15300000000 | 6070000000000 | 0.4422 | 0.2121 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0067 | 0.0012 | 0.0248 | 0.0030 | 0.0781 | 0.0206 | 0.1554 | 0.0495 | 0.1682 | 0.0513 | 0.1992 | 0.0834 | 0.3659 | 0.7909 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0003 | 0.0069 | 0.0006 | 0.0339 | 0.0127 | 0.0714 | 0.0286 | 0.0678 | 0.0219 | 0.0992 | 0.0413 | 0.7200 | 0.8945 | 0.0053 | 0.0096 | 0.0114 | 0.0288 | 0.0220 | 0.0745 | 0.0676 | 0.0962 | 0.1277 | 0.1923 | 0.1634 | 0.1635 | 0.1087 | 0.1130 | 0.1664 | 0.1394 | 0.3275 | 0.1827 | 0.0010 | 0.0043 | 0.0085 | 0.0299 | 0.0768 | 0.1404 | 0.1063 | 0.1358 | 0.4970 | 7 | 9 | 10 | 12 | 16 | 29 | 83 | 200 | 398 | 0.1579 | 24.15 | 4.168 | 0.5959 | 56105.0 | 38900000 | 32800000000 | 31500000000000 | 0.4719 | 0.1982 | 0.0778 | 0.0031 | 0.2645 | 0.0291 | 0.3497 | 0.1507 | 0.1482 | 0.1884 | 0.0819 | 0.2342 | 0.0426 | 0.1740 | 0.0180 | 0.0983 | 0.0098 | 0.0746 | 0.0074 | 0.0478 | 0.0000 | 0.0001 | 0.0004 | 0.0002 | 0.0004 | 0.0003 | 0.0067 | 0.0067 | 0.0467 | 0.0397 | 0.0880 | 0.0720 | 0.0536 | 0.0512 | 0.0899 | 0.0787 | 0.7143 | 0.7511 | 0.0001 | 0.0003 | 0.0004 | 0.0012 | 0.0016 | 0.0016 | 0.0092 | 0.0145 | 0.0557 | 0.0597 | 0.1096 | 0.1123 | 0.0663 | 0.0794 | 0.1060 | 0.1115 | 0.6510 | 0.6194 | 0.0000 | 0.0001 | 0.0019 | 0.0094 | 0.0525 | 0.0917 | 0.0654 | 0.0947 | 0.6842 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 789 | 385 | | 5318 | 5252 | 117.1 | 28.29 | 183.50 | 149.81 | 88 | 95 | 101 | 106 | 111 | 118 | 126 | 135 | 153 | 0.1359 | 714 | 1.185 | 99.25 | 31.11 | 1 | 0.0440 | 234 | 0.0038 | 12.98 | 5.962 | 0.3134 | 14501.7 | 1920000 | 277000000 | 44100000000 | 0.4157 | 0.2302 | 0.0009 | 0.0000 | 0.0020 | 0.0000 | 0.0054 | 0.0000 | 0.0148 | 0.0014 | 0.0594 | 0.0200 | 0.1213 | 0.0451 | 0.1410 | 0.0401 | 0.1627 | 0.0615 | 0.4926 | 0.8319 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0032 | 0.0000 | 0.0092 | 0.0002 | 0.0304 | 0.0127 | 0.0533 | 0.0251 | 0.0612 | 0.0134 | 0.0839 | 0.0215 | 0.7570 | 0.9271 | 0.0036 | 0.0085 | 0.0107 | 0.0142 | 0.0130 | 0.0342 | 0.0627 | 0.0883 | 0.1456 | 0.2023 | 0.1692 | 0.1766 | 0.0994 | 0.0855 | 0.1669 | 0.1595 | 0.3290 | 0.2308 | 0.0013 | 0.0072 | 0.0103 | 0.0354 | 0.0752 | 0.1150 | 0.1115 | 0.1352 | 0.5090 | 34 | 56 | 79 | 108 | 140 | 180 | 233 | 298 | 398 | 0.0028 | 51.84 | 6.696 | 0.3006 | 56111.0 | 22900000 | 11200000000 | 6260000000000 | 0.5751 | 0.1077 | 0.0275 | 0.0017 | 0.1066 | 0.0098 | 0.2575 | 0.0574 | 0.1760 | 0.1074 | 0.1701 | 0.1895 | 0.1401 | 0.1959 | 0.0671 | 0.1430 | 0.0299 | 0.1310 | 0.0251 | 0.1643 | 0.0008 | 0.0000 | 0.0024 | 0.0010 | 0.0052 | 0.0029 | 0.0226 | 0.0226 | 0.0755 | 0.0634 | 0.1156 | 0.0976 | 0.0898 | 0.0789 | 0.1017 | 0.0957 | 0.5866 | 0.6379 | 0.0012 | 0.0007 | 0.0024 | 0.0052 | 0.0125 | 0.0163 | 0.0458 | 0.0570 | 0.0903 | 0.1117 | 0.1729 | 0.1805 | 0.1028 | 0.1139 | 0.1147 | 0.1220 | 0.4575 | 0.3928 | 0.0005 | 0.0044 | 0.0068 | 0.0311 | 0.0856 | 0.1465 | 0.0934 | 0.1226 | 0.5090 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 840 | 632 | | 7599 | 25331 | 439.9 | 83.79 | 168.72 | 276.45 | 340 | 369 | 390 | 410 | 429 | 450 | 476 | 508 | 555 | 0.0492 | 1247 | 1.002 | 122.50 | 43.46 | 1 | 0.0425 | 323 | 0.0006 | 77.97 | 7.638 | 0.1430 | 200554.0 | 94700000 | 46300000000 | 23400000000000 | 0.4550 | 0.1957 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0026 | 0.0000 | 0.0094 | 0.0007 | 0.0535 | 0.0144 | 0.1165 | 0.0319 | 0.1324 | 0.0357 | 0.1602 | 0.0471 | 0.5253 | 0.8703 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0024 | 0.0000 | 0.0278 | 0.0111 | 0.0578 | 0.0182 | 0.0625 | 0.0137 | 0.0881 | 0.0211 | 0.7604 | 0.9358 | 0.0025 | 0.0077 | 0.0101 | 0.0193 | 0.0126 | 0.0386 | 0.0666 | 0.2278 | 0.1265 | 0.2162 | 0.1678 | 0.2355 | 0.1273 | 0.1042 | 0.1669 | 0.0965 | 0.3196 | 0.0541 | 0.0012 | 0.0026 | 0.0096 | 0.0417 | 0.0858 | 0.1214 | 0.1033 | 0.1219 | 0.5125 | 6 | 7 | 9 | 11 | 16 | 45 | 143 | 328 | 583 | 0.1315 | 51.22 | 4.587 | 0.5228 | 104886.0 | 87500000 | 85800000000 | 94300000000000 | 0.5042 | 0.1314 | 0.1174 | 0.0045 | 0.3070 | 0.0508 | 0.2798 | 0.2324 | 0.1277 | 0.2165 | 0.1108 | 0.1884 | 0.0404 | 0.1303 | 0.0113 | 0.0944 | 0.0038 | 0.0477 | 0.0019 | 0.0350 | 0.0001 | 0.0001 | 0.0012 | 0.0004 | 0.0026 | 0.0011 | 0.0093 | 0.0084 | 0.0522 | 0.0465 | 0.0772 | 0.0740 | 0.0532 | 0.0513 | 0.0848 | 0.0734 | 0.7194 | 0.7448 | 0.0001 | 0.0002 | 0.0007 | 0.0008 | 0.0021 | 0.0027 | 0.0093 | 0.0091 | 0.0560 | 0.0627 | 0.0918 | 0.1001 | 0.0656 | 0.0705 | 0.1066 | 0.1206 | 0.6678 | 0.6332 | 0.0003 | 0.0015 | 0.0032 | 0.0089 | 0.0529 | 0.0819 | 0.0600 | 0.0898 | 0.7015 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1046 | 281 | | 697 | 6737 | 49.7 | 11.06 | 107.38 | 98.61 | 35 | 40 | 43 | 46 | 49 | 53 | 56 | 60 | 66 | 0.0687 | 463 | 0.653 | 94.02 | 20.03 | 1 | 0.3989 | 278 | 0.0147 | 2.37 | 4.400 | 0.5020 | 2589.0 | 140960 | 7970000 | 466000000 | 0.3646 | 0.2679 | 0.0024 | 0.0000 | 0.0049 | 0.0000 | 0.0147 | 0.0015 | 0.0293 | 0.0122 | 0.0880 | 0.0518 | 0.1174 | 0.0487 | 0.1418 | 0.0700 | 0.2103 | 0.1035 | 0.3912 | 0.7123 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0179 | 0.0088 | 0.0448 | 0.0423 | 0.0448 | 0.0350 | 0.0538 | 0.0482 | 0.0878 | 0.0496 | 0.7437 | 0.8161 | 0.0000 | 0.0714 | 0.0067 | 0.0714 | 0.0537 | 0.1071 | 0.0604 | 0.2143 | 0.0940 | 0.1429 | 0.0872 | 0.1429 | 0.0940 | 0.2500 | 0.1678 | 0.0000 | 0.4362 | 0.0000 | 0.0000 | 0.0087 | 0.0029 | 0.0320 | 0.0552 | 0.0698 | 0.0756 | 0.1105 | 0.6453 | 16 | 26 | 41 | 57 | 78 | 101 | 132 | 173 | 239 | 0.0142 | 10.47 | 5.299 | 0.4760 | 21253.2 | 5970000 | 2090000000 | 847000000000 | 0.5145 | 0.1485 | 0.0252 | 0.0015 | 0.0572 | 0.0053 | 0.1725 | 0.0393 | 0.1812 | 0.0766 | 0.1764 | 0.1392 | 0.1764 | 0.1702 | 0.1066 | 0.1387 | 0.0640 | 0.1528 | 0.0407 | 0.2764 | 0.0006 | 0.0003 | 0.0013 | 0.0016 | 0.0064 | 0.0045 | 0.0186 | 0.0143 | 0.0578 | 0.0428 | 0.0902 | 0.0659 | 0.0876 | 0.0653 | 0.1139 | 0.0900 | 0.6236 | 0.7153 | 0.0010 | 0.0023 | 0.0048 | 0.0053 | 0.0120 | 0.0164 | 0.0307 | 0.0282 | 0.0801 | 0.0921 | 0.1243 | 0.1268 | 0.0998 | 0.1009 | 0.1166 | 0.1291 | 0.5307 | 0.4988 | 0.0004 | 0.0020 | 0.0086 | 0.0207 | 0.0718 | 0.1128 | 0.0910 | 0.1175 | 0.5752 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 159 | 548 | | 379 | 3429 | 61.1 | 11.87 | 9.11 | 3.08 | 46 | 49 | 53 | 56 | 61 | 64 | 69 | 74 | 78 | 0.1105 | 379 | 1.104 | 39.12 | 14.21 | 3 | 0.2797 | 106 | 0.0614 | 0.78 | 2.978 | 0.7032 | 3871.4 | 253941 | 17200000 | 1190000000 | 0.4114 | 0.2187 | 0.0000 | 0.0000 | 0.0338 | 0.0000 | 0.0211 | 0.0027 | 0.0717 | 0.0133 | 0.1392 | 0.0398 | 0.1477 | 0.0928 | 0.1477 | 0.0398 | 0.1181 | 0.0955 | 0.3207 | 0.7162 | 0.0000 | 0.0000 | 0.0223 | 0.0000 | 0.0096 | 0.0026 | 0.0287 | 0.0132 | 0.0510 | 0.0396 | 0.0701 | 0.0923 | 0.0605 | 0.0343 | 0.0764 | 0.0686 | 0.6815 | 0.7493 | 0.0000 | 0.0000 | 0.0000 | 1.0000 | 0.0519 | 0.0000 | 0.0649 | 0.0000 | 0.2208 | 0.0000 | 0.1818 | 0.0000 | 0.2078 | 0.0000 | 0.1688 | 0.0000 | 0.1039 | 0.0000 | 0.0000 | 0.0209 | 0.0105 | 0.0419 | 0.0995 | 0.0942 | 0.1047 | 0.1152 | 0.5131 | 5 | 7 | 7 | 8 | 9 | 10 | 10 | 11 | 13 | 0.0137 | 13.19 | 4.745 | 0.3048 | 92.4 | 1038.16 | 12866.9 | 175722 | 0.4767 | 0.1774 | 0.0306 | 0.0011 | 0.0977 | 0.0053 | 0.1939 | 0.0174 | 0.2558 | 0.0474 | 0.2165 | 0.0913 | 0.1348 | 0.1588 | 0.0547 | 0.2421 | 0.0160 | 0.2736 | 0.0000 | 0.1629 | 0.0040 | 0.0000 | 0.0215 | 0.0007 | 0.0553 | 0.0059 | 0.0975 | 0.0180 | 0.1615 | 0.0475 | 0.1708 | 0.0992 | 0.1550 | 0.1490 | 0.1519 | 0.2449 | 0.1826 | 0.4348 | 0.1258 | 0.1928 | 0.1479 | 0.1639 | 0.1336 | 0.1470 | 0.1291 | 0.1012 | 0.1049 | 0.1036 | 0.0894 | 0.1108 | 0.0993 | 0.0916 | 0.1038 | 0.0675 | 0.0662 | 0.0217 | 0.0221 | 0.0550 | 0.1024 | 0.1185 | 0.1422 | 0.1212 | 0.1315 | 0.1245 | 0.1827 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 506 | 842 | | 4164 | 7027 | 174.9 | 56.54 | 178.00 | 147.56 | 112 | 130 | 142 | 152 | 163 | 178 | 195 | 217 | 248 | 0.0992 | 697 | 1.133 | 87.73 | 29.97 | 1 | 0.0531 | 221 | 0.0010 | 60.00 | 7.142 | 0.1752 | 33770.8 | 7210000 | 1700000000 | 440000000000 | 0.4464 | 0.2087 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0141 | 0.0006 | 0.0522 | 0.0044 | 0.1370 | 0.0397 | 0.1936 | 0.0823 | 0.1921 | 0.0887 | 0.1775 | 0.1264 | 0.2301 | 0.6580 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0116 | 0.0021 | 0.0475 | 0.0234 | 0.0857 | 0.0412 | 0.0834 | 0.0368 | 0.1113 | 0.0577 | 0.6565 | 0.8388 | 0.0031 | 0.0022 | 0.0021 | 0.0153 | 0.0073 | 0.0131 | 0.0636 | 0.1160 | 0.1366 | 0.1751 | 0.1783 | 0.2079 | 0.1220 | 0.1072 | 0.1689 | 0.1379 | 0.3180 | 0.2254 | 0.0011 | 0.0006 | 0.0034 | 0.0311 | 0.0911 | 0.1324 | 0.1046 | 0.1414 | 0.4943 | 27 | 50 | 74 | 106 | 140 | 178 | 225 | 292 | 389 | 0.0022 | 67.53 | 7.034 | 0.2591 | 53457.0 | 21400000 | 10400000000 | 5770000000000 | 0.4709 | 0.1839 | 0.0246 | 0.0021 | 0.1054 | 0.0050 | 0.2141 | 0.0504 | 0.1742 | 0.0881 | 0.1708 | 0.1448 | 0.1351 | 0.1725 | 0.0799 | 0.1469 | 0.0654 | 0.1452 | 0.0306 | 0.2451 | 0.0003 | 0.0007 | 0.0014 | 0.0000 | 0.0041 | 0.0026 | 0.0151 | 0.0086 | 0.0704 | 0.0509 | 0.1194 | 0.0961 | 0.0898 | 0.0692 | 0.1292 | 0.1056 | 0.5703 | 0.6664 | 0.0022 | 0.0022 | 0.0035 | 0.0049 | 0.0101 | 0.0121 | 0.0321 | 0.0351 | 0.0981 | 0.1185 | 0.1438 | 0.1580 | 0.1130 | 0.0971 | 0.1328 | 0.1377 | 0.4644 | 0.4344 | 0.0004 | 0.0028 | 0.0042 | 0.0276 | 0.0850 | 0.1324 | 0.0967 | 0.1328 | 0.5181 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 438 | 881 | | 789 | 8063 | 74.1 | 31.85 | 47.97 | 131.71 | 30 | 40 | 55 | 65 | 73 | 81 | 92 | 101 | 116 | 0.0633 | 510 | 0.386 | 127.58 | 22.47 | 2 | 0.5982 | 472 | 0.0024 | 38.72 | 6.180 | 0.1858 | 6504.0 | 641928 | 68900000 | 7880000000 | 0.3632 | 0.2507 | 0.0000 | 0.0000 | 0.0038 | 0.0000 | 0.0538 | 0.0043 | 0.1000 | 0.0172 | 0.2115 | 0.0948 | 0.1808 | 0.1401 | 0.1846 | 0.1185 | 0.1692 | 0.1789 | 0.0962 | 0.4461 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0135 | 0.0049 | 0.0558 | 0.0395 | 0.0673 | 0.0543 | 0.0635 | 0.0329 | 0.0885 | 0.0625 | 0.7115 | 0.8059 | 0.0000 | 0.0000 | 0.0154 | 0.0139 | 0.0077 | 0.0625 | 0.0346 | 0.0694 | 0.0962 | 0.1319 | 0.1269 | 0.1667 | 0.1038 | 0.1528 | 0.1692 | 0.1250 | 0.4462 | 0.2778 | 0.0026 | 0.0000 | 0.0026 | 0.0179 | 0.0742 | 0.0818 | 0.1023 | 0.1560 | 0.5627 | 11 | 13 | 15 | 16 | 18 | 20 | 22 | 26 | 61 | 0.4823 | 4.88 | 1.769 | 0.8585 | 19647.5 | 17700000 | 20000000000 | 25500000000000 | 0.6771 | 0.1020 | 0.0533 | 0.0311 | 0.1557 | 0.0251 | 0.2172 | 0.0621 | 0.2377 | 0.0932 | 0.2008 | 0.1657 | 0.0820 | 0.2027 | 0.0287 | 0.1686 | 0.0164 | 0.1198 | 0.0082 | 0.1317 | 0.0000 | 0.0147 | 0.0009 | 0.0077 | 0.0046 | 0.0105 | 0.0352 | 0.0252 | 0.0897 | 0.0617 | 0.1175 | 0.0870 | 0.1027 | 0.1024 | 0.1036 | 0.1080 | 0.5458 | 0.5827 | 0.0012 | 0.0013 | 0.0036 | 0.0027 | 0.0060 | 0.0080 | 0.0239 | 0.0213 | 0.1004 | 0.1120 | 0.1470 | 0.1600 | 0.1016 | 0.0973 | 0.1147 | 0.1307 | 0.5018 | 0.4667 | 0.0000 | 0.0011 | 0.0074 | 0.0253 | 0.1077 | 0.1267 | 0.0940 | 0.1109 | 0.5269 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 201 | 479 | | 6474 | 26300 | 321.0 | 57.21 | 100.08 | 124.51 | 249 | 270 | 287 | 303 | 318 | 334 | 351 | 372 | 398 | 0.0455 | 1196 | 1.134 | 99.86 | 37.59 | 2 | 0.0394 | 255 | 0.0006 | 73.06 | 7.553 | 0.1323 | 106297.0 | 36300000 | 12700000000 | 4580000000000 | 0.4555 | 0.1968 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0030 | 0.0002 | 0.0144 | 0.0008 | 0.0453 | 0.0123 | 0.1133 | 0.0261 | 0.1258 | 0.0247 | 0.1709 | 0.0467 | 0.5257 | 0.8892 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0002 | 0.0069 | 0.0003 | 0.0227 | 0.0113 | 0.0501 | 0.0206 | 0.0538 | 0.0157 | 0.0774 | 0.0244 | 0.7881 | 0.9275 | 0.0044 | 0.0805 | 0.0187 | 0.0575 | 0.0430 | 0.1839 | 0.0926 | 0.0920 | 0.1599 | 0.3103 | 0.1985 | 0.1379 | 0.1279 | 0.0460 | 0.1709 | 0.0805 | 0.1841 | 0.0115 | 0.0010 | 0.0025 | 0.0127 | 0.0290 | 0.0762 | 0.1275 | 0.1093 | 0.1393 | 0.5025 | 11 | 13 | 15 | 20 | 36 | 70 | 125 | 189 | 272 | 0.0574 | 15.56 | 4.832 | 0.5328 | 25517.2 | 9400000 | 4360000000 | 2400000000000 | 0.4719 | 0.1702 | 0.0761 | 0.0028 | 0.2702 | 0.0198 | 0.3311 | 0.1800 | 0.1322 | 0.2075 | 0.0992 | 0.2192 | 0.0530 | 0.1607 | 0.0236 | 0.0959 | 0.0105 | 0.0697 | 0.0042 | 0.0445 | 0.0001 | 0.0000 | 0.0007 | 0.0004 | 0.0009 | 0.0012 | 0.0101 | 0.0086 | 0.0551 | 0.0465 | 0.1067 | 0.0874 | 0.0756 | 0.0609 | 0.1039 | 0.0939 | 0.6470 | 0.7011 | 0.0004 | 0.0005 | 0.0005 | 0.0019 | 0.0037 | 0.0034 | 0.0152 | 0.0180 | 0.0736 | 0.0826 | 0.1416 | 0.1590 | 0.0968 | 0.1084 | 0.1346 | 0.1429 | 0.5337 | 0.4833 | 0.0006 | 0.0003 | 0.0023 | 0.0133 | 0.0603 | 0.1279 | 0.0841 | 0.1215 | 0.5898 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 674 | 423 | | 2494 | 12270 | 100.8 | 25.07 | 240.02 | 220.97 | 70 | 79 | 87 | 94 | 100 | 105 | 112 | 120 | 134 | 0.0824 | 1011 | 0.313 | 186.85 | 42.64 | 3 | 0.3091 | 771 | 0.0033 | 14.33 | 5.992 | 0.3037 | 10783.5 | 1220000 | 145000000 | 18200000000 | 0.4342 | 0.2159 | 0.0007 | 0.0000 | 0.0034 | 0.0000 | 0.0189 | 0.0009 | 0.0444 | 0.0076 | 0.1098 | 0.0438 | 0.1825 | 0.0795 | 0.1589 | 0.0831 | 0.1845 | 0.1273 | 0.2970 | 0.6577 | 0.0005 | 0.0000 | 0.0015 | 0.0000 | 0.0056 | 0.0004 | 0.0153 | 0.0054 | 0.0490 | 0.0321 | 0.0842 | 0.0534 | 0.0745 | 0.0434 | 0.0990 | 0.0671 | 0.6704 | 0.7982 | 0.0042 | 0.0062 | 0.0253 | 0.0186 | 0.0547 | 0.1056 | 0.0674 | 0.1801 | 0.1558 | 0.1988 | 0.1853 | 0.1801 | 0.1137 | 0.1242 | 0.1726 | 0.1056 | 0.2211 | 0.0807 | 0.0025 | 0.0050 | 0.0091 | 0.0380 | 0.0809 | 0.1353 | 0.1089 | 0.1601 | 0.4604 | 20 | 40 | 82 | 132 | 185 | 240 | 304 | 392 | 551 | 0.0090 | 45.80 | 6.615 | 0.3329 | 106431.0 | 63700000 | 46200000000 | 38100000000000 | 0.5619 | 0.1212 | 0.0208 | 0.0008 | 0.1223 | 0.0067 | 0.2152 | 0.0569 | 0.1437 | 0.0937 | 0.1675 | 0.1632 | 0.1477 | 0.2010 | 0.0898 | 0.1402 | 0.0589 | 0.1320 | 0.0340 | 0.2056 | 0.0003 | 0.0000 | 0.0013 | 0.0004 | 0.0035 | 0.0018 | 0.0145 | 0.0100 | 0.0650 | 0.0520 | 0.1181 | 0.0946 | 0.0828 | 0.0744 | 0.1196 | 0.1048 | 0.5949 | 0.6619 | 0.0007 | 0.0025 | 0.0030 | 0.0053 | 0.0117 | 0.0171 | 0.0319 | 0.0421 | 0.0986 | 0.1075 | 0.1463 | 0.1430 | 0.1003 | 0.0888 | 0.1232 | 0.1174 | 0.4843 | 0.4763 | 0.0010 | 0.0010 | 0.0057 | 0.0267 | 0.0786 | 0.1316 | 0.0970 | 0.1210 | 0.5374 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 892 | 528 | | 438 | 4290 | 99.4 | 30.58 | 45.69 | 79.25 | 57 | 73 | 84 | 93 | 98 | 106 | 113 | 122 | 143 | 0.0991 | 425 | 0.186 | 244.68 | 30.23 | 3 | 2.7374 | 1199 | 0.0033 | 47.98 | 5.825 | 0.1324 | 10807.1 | 1270000 | 158000000 | 20800000000 | 0.3355 | 0.2955 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0091 | 0.0000 | 0.0727 | 0.0060 | 0.1182 | 0.0925 | 0.1318 | 0.0896 | 0.1591 | 0.0985 | 0.2045 | 0.1254 | 0.3045 | 0.5881 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0123 | 0.0026 | 0.0679 | 0.0596 | 0.0494 | 0.0570 | 0.0710 | 0.0440 | 0.0802 | 0.0648 | 0.7160 | 0.7720 | 0.0096 | 0.0000 | 0.0192 | 0.0000 | 0.0096 | 0.0392 | 0.0288 | 0.0196 | 0.1154 | 0.1961 | 0.1250 | 0.1765 | 0.0962 | 0.1176 | 0.1731 | 0.2745 | 0.4231 | 0.1765 | 0.0046 | 0.0092 | 0.0184 | 0.0276 | 0.0783 | 0.1014 | 0.1060 | 0.1382 | 0.5161 | 14 | 17 | 19 | 23 | 26 | 30 | 36 | 48 | 74 | 0.2037 | 1.21 | 2.394 | 0.8309 | 8367.0 | 4140000 | 2720000000 | 1970000000000 | 0.5493 | 0.1523 | 0.0193 | 0.0111 | 0.0456 | 0.0222 | 0.1298 | 0.0341 | 0.1333 | 0.0632 | 0.1754 | 0.1091 | 0.2140 | 0.1543 | 0.1386 | 0.1508 | 0.0930 | 0.1737 | 0.0509 | 0.2814 | 0.0072 | 0.0081 | 0.0087 | 0.0163 | 0.0223 | 0.0229 | 0.0405 | 0.0366 | 0.0692 | 0.0630 | 0.0922 | 0.0885 | 0.0978 | 0.0976 | 0.1065 | 0.1205 | 0.5556 | 0.5465 | 0.0029 | 0.0000 | 0.0116 | 0.0303 | 0.0305 | 0.0227 | 0.0349 | 0.0360 | 0.0799 | 0.0833 | 0.1105 | 0.1174 | 0.1017 | 0.0947 | 0.1366 | 0.1193 | 0.4913 | 0.4962 | 0.0022 | 0.0076 | 0.0174 | 0.0239 | 0.0827 | 0.0914 | 0.1012 | 0.1164 | 0.5571 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1262 | 191 | | 1146 | 5093 | 90.2 | 37.96 | 173.01 | 291.74 | 37 | 56 | 70 | 80 | 89 | 98 | 108 | 122 | 139 | 0.1056 | 538 | 0.246 | 326.81 | 58.25 | 3 | 1.2321 | 1412 | 0.0022 | 29.57 | 6.284 | 0.2125 | 9584.0 | 1150000 | 154000000 | 22500000000 | 0.3879 | 0.2271 | 0.0045 | 0.0000 | 0.0182 | 0.0000 | 0.0795 | 0.0040 | 0.0932 | 0.0173 | 0.1295 | 0.0840 | 0.1705 | 0.1280 | 0.1705 | 0.1333 | 0.1955 | 0.1453 | 0.1386 | 0.4880 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0064 | 0.0032 | 0.0446 | 0.0319 | 0.0841 | 0.0554 | 0.0828 | 0.0405 | 0.1338 | 0.0692 | 0.6459 | 0.7998 | 0.0000 | 0.0106 | 0.0087 | 0.0212 | 0.0203 | 0.0159 | 0.0580 | 0.0847 | 0.1130 | 0.2328 | 0.1652 | 0.2011 | 0.1275 | 0.1164 | 0.1739 | 0.1270 | 0.3333 | 0.1905 | 0.0035 | 0.0018 | 0.0089 | 0.0319 | 0.0904 | 0.1294 | 0.1188 | 0.1489 | 0.4663 | 14 | 16 | 18 | 21 | 25 | 39 | 104 | 323 | 583 | 0.0764 | 34.57 | 4.571 | 0.5346 | 115023.0 | 109000000 | 127000000000 | 170000000000000 | 0.7263 | 0.0444 | 0.0738 | 0.0122 | 0.3020 | 0.0550 | 0.3087 | 0.1498 | 0.1477 | 0.2385 | 0.1208 | 0.2599 | 0.0201 | 0.1346 | 0.0134 | 0.0642 | 0.0134 | 0.0367 | 0.0000 | 0.0489 | 0.0000 | 0.0007 | 0.0028 | 0.0013 | 0.0028 | 0.0033 | 0.0264 | 0.0209 | 0.0674 | 0.0712 | 0.1035 | 0.0935 | 0.0757 | 0.0745 | 0.1070 | 0.1085 | 0.6143 | 0.6261 | 0.0016 | 0.0000 | 0.0023 | 0.0025 | 0.0047 | 0.0183 | 0.0287 | 0.0241 | 0.0636 | 0.0665 | 0.1116 | 0.1155 | 0.0853 | 0.0840 | 0.1124 | 0.1139 | 0.5899 | 0.5752 | 0.0007 | 0.0029 | 0.0066 | 0.0269 | 0.0655 | 0.1077 | 0.0852 | 0.1033 | 0.6012 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1152 | 223 | | 1691 | 12352 | 99.2 | 17.11 | 46.92 | 69.30 | 79 | 84 | 88 | 92 | 96 | 101 | 107 | 114 | 124 | 0.0508 | 627 | 1.190 | 91.98 | 34.23 | 1 | 0.1366 | 231 | 0.0065 | 7.72 | 5.324 | 0.3702 | 10134.8 | 1070000 | 116000000 | 12900000000 | 0.3875 | 0.2575 | 0.0008 | 0.0000 | 0.0040 | 0.0000 | 0.0127 | 0.0000 | 0.0343 | 0.0024 | 0.0741 | 0.0253 | 0.1076 | 0.0519 | 0.1139 | 0.0404 | 0.1777 | 0.0821 | 0.4749 | 0.7978 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0047 | 0.0000 | 0.0206 | 0.0018 | 0.0419 | 0.0231 | 0.0599 | 0.0420 | 0.0573 | 0.0213 | 0.0879 | 0.0390 | 0.7264 | 0.8729 | 0.0121 | 0.1176 | 0.0040 | 0.1765 | 0.0526 | 0.2353 | 0.0931 | 0.2941 | 0.1336 | 0.1176 | 0.1903 | 0.0588 | 0.1579 | 0.0000 | 0.1741 | 0.0000 | 0.1822 | 0.0000 | 0.0039 | 0.0065 | 0.0310 | 0.0233 | 0.0802 | 0.1125 | 0.1035 | 0.1475 | 0.4916 | 7 | 10 | 13 | 17 | 23 | 32 | 44 | 64 | 112 | 0.0318 | 9.40 | 4.580 | 0.5581 | 7003.8 | 2350000 | 1290000000 | 919000000000 | 0.6011 | 0.1309 | 0.0239 | 0.0061 | 0.0710 | 0.0163 | 0.1253 | 0.0476 | 0.1857 | 0.0850 | 0.1744 | 0.1282 | 0.1459 | 0.1473 | 0.1187 | 0.1486 | 0.1054 | 0.1514 | 0.0497 | 0.2694 | 0.0028 | 0.0028 | 0.0058 | 0.0052 | 0.0106 | 0.0099 | 0.0311 | 0.0268 | 0.0659 | 0.0579 | 0.0954 | 0.0806 | 0.0809 | 0.0798 | 0.1143 | 0.1059 | 0.5934 | 0.6311 | 0.0056 | 0.0063 | 0.0141 | 0.0117 | 0.0159 | 0.0184 | 0.0286 | 0.0284 | 0.0766 | 0.0755 | 0.1048 | 0.1172 | 0.0886 | 0.0893 | 0.1172 | 0.1247 | 0.5485 | 0.5286 | 0.0026 | 0.0105 | 0.0228 | 0.0324 | 0.0762 | 0.0964 | 0.0836 | 0.1155 | 0.5599 | ||
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 354 | 420 | | 1298 | 8819 | 703.5 | 137.06 | 40.06 | 42.60 | 498 | 566 | 622 | 685 | 723 | 762 | 800 | 837 | 868 | 0.0693 | 611 | 0.939 | 34.21 | 8.06 | 4 | 0.0624 | 81 | 0.0013 | 60.83 | 6.801 | 0.1510 | 513652.0 | 387000000 | 299000000000 | 236000000000000 | 0.4003 | 0.2202 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0012 | 0.0000 | 0.0085 | 0.0008 | 0.0932 | 0.0281 | 0.1538 | 0.0532 | 0.1356 | 0.0258 | 0.1586 | 0.0446 | 0.4479 | 0.8475 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0008 | 0.0458 | 0.0281 | 0.0715 | 0.0532 | 0.0372 | 0.0258 | 0.0696 | 0.0446 | 0.7741 | 0.8475 | 0.0045 | 0.0000 | 0.0135 | 0.0000 | 0.0269 | 0.0000 | 0.0628 | 0.0000 | 0.1704 | 0.0000 | 0.1883 | 0.0000 | 0.1390 | 0.0000 | 0.1749 | 0.0000 | 0.2197 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0124 | 0.0634 | 0.1007 | 0.0703 | 0.1131 | 0.6386 | 12 | 14 | 16 | 19 | 24 | 30 | 39 | 56 | 96 | 0.0579 | 5.04 | 3.928 | 0.6486 | 3419.8 | 510086 | 108000000 | 28300000000 | 0.4195 | 0.2154 | 0.0197 | 0.0099 | 0.0599 | 0.0129 | 0.1125 | 0.0254 | 0.1289 | 0.0420 | 0.1724 | 0.0884 | 0.1634 | 0.1256 | 0.1330 | 0.1219 | 0.1371 | 0.1819 | 0.0731 | 0.3921 | 0.0057 | 0.0056 | 0.0106 | 0.0065 | 0.0157 | 0.0127 | 0.0205 | 0.0169 | 0.0410 | 0.0340 | 0.0651 | 0.0498 | 0.0576 | 0.0514 | 0.0923 | 0.0910 | 0.6916 | 0.7322 | 0.0014 | 0.0017 | 0.0062 | 0.0028 | 0.0105 | 0.0062 | 0.0253 | 0.0258 | 0.0581 | 0.0624 | 0.0781 | 0.0983 | 0.0696 | 0.0736 | 0.0948 | 0.0893 | 0.6560 | 0.6399 | 0.0019 | 0.0054 | 0.0101 | 0.0260 | 0.0490 | 0.0707 | 0.0634 | 0.1014 | 0.6720 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1249 | 769 | | 4803 | 11247 | 502.2 | 83.00 | 67.05 | 122.38 | 382 | 431 | 463 | 488 | 508 | 528 | 552 | 579 | 608 | 0.0648 | 729 | 1.156 | 88.46 | 33.06 | 1 | 0.0477 | 229 | 0.0014 | 23.98 | 6.830 | 0.2358 | 259094.0 | 137000000 | 73800000000 | 40500000000000 | 0.4284 | 0.2133 | 0.0011 | 0.0000 | 0.0019 | 0.0000 | 0.0044 | 0.0000 | 0.0091 | 0.0002 | 0.0299 | 0.0136 | 0.0517 | 0.0206 | 0.0575 | 0.0124 | 0.0811 | 0.0183 | 0.7632 | 0.9350 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0002 | 0.0170 | 0.0136 | 0.0276 | 0.0206 | 0.0218 | 0.0124 | 0.0377 | 0.0183 | 0.8937 | 0.9350 | 0.0072 | 0.0000 | 0.0181 | 0.0000 | 0.0325 | 0.0000 | 0.0597 | 0.0000 | 0.0868 | 0.0000 | 0.1374 | 0.0000 | 0.1230 | 0.0000 | 0.1754 | 0.0000 | 0.3599 | 0.0000 | 0.0019 | 0.0016 | 0.0054 | 0.0140 | 0.0384 | 0.0594 | 0.0602 | 0.0889 | 0.7301 | 6 | 8 | 10 | 12 | 15 | 20 | 38 | 86 | 207 | 0.1665 | 6.51 | 3.350 | 0.6502 | 19470.7 | 8860000 | 4860000000 | 2970000000000 | 0.5816 | 0.0962 | 0.0324 | 0.0043 | 0.1477 | 0.0208 | 0.2216 | 0.0720 | 0.2090 | 0.1276 | 0.1658 | 0.1753 | 0.1189 | 0.1840 | 0.0613 | 0.1372 | 0.0216 | 0.1345 | 0.0216 | 0.1441 | 0.0007 | 0.0003 | 0.0010 | 0.0009 | 0.0034 | 0.0039 | 0.0172 | 0.0128 | 0.0540 | 0.0538 | 0.0890 | 0.0805 | 0.0639 | 0.0589 | 0.0907 | 0.0838 | 0.6801 | 0.7050 | 0.0000 | 0.0005 | 0.0013 | 0.0019 | 0.0030 | 0.0033 | 0.0166 | 0.0196 | 0.0675 | 0.0650 | 0.0968 | 0.1182 | 0.0739 | 0.0715 | 0.0994 | 0.1005 | 0.6416 | 0.6196 | 0.0004 | 0.0015 | 0.0034 | 0.0145 | 0.0574 | 0.1015 | 0.0624 | 0.0915 | 0.6673 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 771 | 729 | | 699 | 8074 | 51.0 | 15.12 | 134.99 | 188.23 | 31 | 35 | 40 | 45 | 50 | 56 | 62 | 67 | 72 | 0.0588 | 475 | 1.025 | 40.01 | 10.20 | 1 | 0.1373 | 96 | 0.0059 | 6.82 | 5.319 | 0.3605 | 2826.1 | 167621 | 10500000 | 678000000 | 0.3593 | 0.2671 | 0.0074 | 0.0000 | 0.0223 | 0.0106 | 0.0186 | 0.0195 | 0.0483 | 0.0283 | 0.1264 | 0.0496 | 0.1561 | 0.0637 | 0.1822 | 0.0991 | 0.2119 | 0.1558 | 0.2268 | 0.5735 | 0.0000 | 0.0000 | 0.0021 | 0.0016 | 0.0021 | 0.0094 | 0.0125 | 0.0141 | 0.0480 | 0.0297 | 0.0438 | 0.0375 | 0.0438 | 0.0531 | 0.0710 | 0.0688 | 0.7766 | 0.7859 | 0.0000 | 0.0267 | 0.0095 | 0.0533 | 0.0095 | 0.0533 | 0.0714 | 0.1867 | 0.0571 | 0.1333 | 0.0857 | 0.2000 | 0.1333 | 0.1733 | 0.1762 | 0.1467 | 0.4571 | 0.0267 | 0.0000 | 0.0029 | 0.0086 | 0.0201 | 0.0430 | 0.0630 | 0.0516 | 0.0860 | 0.7249 | 17 | 20 | 22 | 27 | 42 | 69 | 121 | 231 | 414 | 0.1036 | 10.05 | 4.238 | 0.6273 | 53649.5 | 30800000 | 20700000000 | 15500000000000 | 0.6068 | 0.0942 | 0.0493 | 0.0037 | 0.1637 | 0.0266 | 0.2249 | 0.1322 | 0.1657 | 0.1506 | 0.1400 | 0.1304 | 0.1183 | 0.1680 | 0.0552 | 0.1074 | 0.0414 | 0.0973 | 0.0414 | 0.1837 | 0.0004 | 0.0007 | 0.0012 | 0.0013 | 0.0046 | 0.0030 | 0.0150 | 0.0167 | 0.0547 | 0.0407 | 0.0875 | 0.0781 | 0.0586 | 0.0524 | 0.0848 | 0.0851 | 0.6933 | 0.7219 | 0.0005 | 0.0005 | 0.0019 | 0.0042 | 0.0043 | 0.0100 | 0.0168 | 0.0173 | 0.0570 | 0.0614 | 0.1049 | 0.0992 | 0.0608 | 0.0719 | 0.0967 | 0.1028 | 0.6571 | 0.6327 | 0.0000 | 0.0039 | 0.0035 | 0.0195 | 0.0500 | 0.0925 | 0.0626 | 0.0947 | 0.6733 |