High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 173 | 580 | | 3314 | 11955 | 517.2 | 91.88 | 119.57 | 243.85 | 373 | 433 | 487 | 512 | 531 | 550 | 573 | 598 | 624 | 0.0613 | 733 | 0.446 | 104.39 | 23.32 | 3 | 0.0993 | 329 | 0.0010 | 41.90 | 7.124 | 0.2030 | 275939.0 | 151000000 | 84400000000 | 48000000000000 | 0.4375 | 0.1965 | 0.0000 | 0.0000 | 0.0029 | 0.0003 | 0.0017 | 0.0003 | 0.0071 | 0.0009 | 0.0384 | 0.0163 | 0.0744 | 0.0359 | 0.0660 | 0.0157 | 0.0994 | 0.0273 | 0.7101 | 0.9033 | 0.0000 | 0.0000 | 0.0011 | 0.0003 | 0.0000 | 0.0003 | 0.0014 | 0.0009 | 0.0206 | 0.0163 | 0.0343 | 0.0359 | 0.0220 | 0.0157 | 0.0354 | 0.0273 | 0.8851 | 0.9033 | 0.0134 | 0.0000 | 0.0160 | 0.0000 | 0.0428 | 0.0000 | 0.0856 | 0.0000 | 0.1096 | 0.0000 | 0.1791 | 0.0000 | 0.1123 | 0.0000 | 0.1417 | 0.0000 | 0.2995 | 0.0000 | 0.0005 | 0.0042 | 0.0094 | 0.0141 | 0.0381 | 0.0522 | 0.0637 | 0.0914 | 0.7262 | 9 | 12 | 14 | 16 | 21 | 31 | 57 | 130 | 371 | 0.1465 | 4.98 | 3.299 | 0.6421 | 73753.8 | 72700000 | 87000000000 | 116000000000000 | 0.4905 | 0.1557 | 0.0398 | 0.0000 | 0.1155 | 0.0121 | 0.1474 | 0.0864 | 0.1932 | 0.1021 | 0.1972 | 0.1690 | 0.1554 | 0.1820 | 0.0777 | 0.1328 | 0.0498 | 0.1235 | 0.0239 | 0.1922 | 0.0000 | 0.0000 | 0.0025 | 0.0012 | 0.0051 | 0.0044 | 0.0108 | 0.0097 | 0.0375 | 0.0400 | 0.0563 | 0.0512 | 0.0512 | 0.0465 | 0.0776 | 0.0787 | 0.7589 | 0.7684 | 0.0000 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0028 | 0.0119 | 0.0127 | 0.0419 | 0.0409 | 0.0608 | 0.0682 | 0.0591 | 0.0564 | 0.0784 | 0.0804 | 0.7466 | 0.7377 | 0.0008 | 0.0008 | 0.0028 | 0.0097 | 0.0399 | 0.0565 | 0.0480 | 0.0871 | 0.7543 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 780 | 643 | | 4246 | 9503 | 153.2 | 43.23 | 163.95 | 111.35 | 107 | 118 | 127 | 135 | 144 | 155 | 167 | 184 | 213 | 0.0930 | 884 | 1.215 | 66.84 | 30.36 | 1 | 0.0445 | 189 | 0.0016 | 33.38 | 6.721 | 0.2068 | 25324.3 | 4540000 | 884000000 | 186000000000 | 0.4222 | 0.2177 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0065 | 0.0005 | 0.0285 | 0.0037 | 0.1085 | 0.0264 | 0.1876 | 0.0650 | 0.1746 | 0.0647 | 0.2040 | 0.0836 | 0.2891 | 0.7561 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0110 | 0.0012 | 0.0397 | 0.0171 | 0.0784 | 0.0293 | 0.0800 | 0.0238 | 0.1178 | 0.0358 | 0.6711 | 0.8927 | 0.0023 | 0.0000 | 0.0047 | 0.0049 | 0.0140 | 0.0196 | 0.0756 | 0.1225 | 0.1465 | 0.1716 | 0.1686 | 0.2059 | 0.1128 | 0.1152 | 0.1419 | 0.1127 | 0.3337 | 0.2475 | 0.0011 | 0.0022 | 0.0056 | 0.0332 | 0.0917 | 0.1507 | 0.1074 | 0.1277 | 0.4803 | 49 | 74 | 95 | 116 | 139 | 164 | 198 | 245 | 310 | 0.0019 | 44.15 | 6.783 | 0.2632 | 39278.6 | 12800000 | 5480000000 | 3000000000000 | 0.5562 | 0.1215 | 0.0241 | 0.0012 | 0.0805 | 0.0056 | 0.1411 | 0.0391 | 0.1416 | 0.0770 | 0.1754 | 0.1299 | 0.1546 | 0.1697 | 0.1157 | 0.1456 | 0.0995 | 0.1528 | 0.0676 | 0.2792 | 0.0014 | 0.0002 | 0.0026 | 0.0009 | 0.0069 | 0.0057 | 0.0242 | 0.0137 | 0.0746 | 0.0545 | 0.1063 | 0.0876 | 0.0950 | 0.0778 | 0.1295 | 0.1115 | 0.5595 | 0.6480 | 0.0031 | 0.0018 | 0.0045 | 0.0054 | 0.0118 | 0.0145 | 0.0478 | 0.0559 | 0.1069 | 0.1335 | 0.1491 | 0.1807 | 0.1301 | 0.1326 | 0.1557 | 0.1685 | 0.3910 | 0.3070 | 0.0018 | 0.0050 | 0.0089 | 0.0404 | 0.0908 | 0.1409 | 0.1049 | 0.1375 | 0.4699 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 686 | 625 | | 6653 | 21616 | 335.3 | 63.66 | 169.19 | 212.41 | 264 | 281 | 295 | 309 | 325 | 342 | 362 | 385 | 425 | 0.0403 | 871 | 1.098 | 108.24 | 36.69 | 1 | 0.0412 | 274 | 0.0007 | 66.56 | 7.535 | 0.1518 | 116505.0 | 42000000 | 15700000000 | 6090000000000 | 0.4550 | 0.1972 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0023 | 0.0002 | 0.0068 | 0.0011 | 0.0474 | 0.0135 | 0.1064 | 0.0297 | 0.1104 | 0.0278 | 0.1437 | 0.0363 | 0.5825 | 0.8914 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0029 | 0.0000 | 0.0239 | 0.0090 | 0.0529 | 0.0155 | 0.0543 | 0.0084 | 0.0731 | 0.0141 | 0.7917 | 0.9529 | 0.0030 | 0.0000 | 0.0120 | 0.0243 | 0.0200 | 0.0208 | 0.0430 | 0.1250 | 0.1289 | 0.1736 | 0.1548 | 0.2153 | 0.1009 | 0.1215 | 0.1419 | 0.1458 | 0.3956 | 0.1736 | 0.0017 | 0.0010 | 0.0113 | 0.0284 | 0.0825 | 0.1140 | 0.1062 | 0.1308 | 0.5240 | 11 | 13 | 15 | 21 | 59 | 135 | 223 | 332 | 480 | 0.0461 | 55.65 | 5.697 | 0.4308 | 73741.6 | 43100000 | 29900000000 | 23400000000000 | 0.4089 | 0.2338 | 0.0463 | 0.0015 | 0.1935 | 0.0167 | 0.2745 | 0.1152 | 0.1777 | 0.1388 | 0.1357 | 0.1962 | 0.0901 | 0.1912 | 0.0542 | 0.1307 | 0.0213 | 0.1096 | 0.0067 | 0.1001 | 0.0001 | 0.0001 | 0.0014 | 0.0005 | 0.0035 | 0.0017 | 0.0088 | 0.0064 | 0.0446 | 0.0382 | 0.0850 | 0.0684 | 0.0604 | 0.0514 | 0.0846 | 0.0704 | 0.7116 | 0.7629 | 0.0009 | 0.0006 | 0.0029 | 0.0029 | 0.0063 | 0.0060 | 0.0129 | 0.0147 | 0.0599 | 0.0658 | 0.1035 | 0.1203 | 0.0786 | 0.0886 | 0.1056 | 0.1095 | 0.6295 | 0.5914 | 0.0001 | 0.0022 | 0.0036 | 0.0127 | 0.0496 | 0.0976 | 0.0729 | 0.0936 | 0.6678 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1078 | 523 | | 14942 | 30535 | 213.6 | 65.41 | 182.99 | 225.98 | 137 | 159 | 176 | 193 | 208 | 224 | 242 | 265 | 299 | 0.0495 | 1511 | 0.501 | 139.13 | 33.29 | 9 | 0.0285 | 426 | 0.0011 | 32.46 | 7.146 | 0.2116 | 49882.5 | 12600000 | 3430000000 | 996000000000 | 0.4707 | 0.1872 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0114 | 0.0010 | 0.0396 | 0.0054 | 0.1050 | 0.0284 | 0.1755 | 0.0659 | 0.1723 | 0.0644 | 0.1742 | 0.0921 | 0.3187 | 0.7427 | 0.0005 | 0.0000 | 0.0007 | 0.0001 | 0.0015 | 0.0002 | 0.0105 | 0.0022 | 0.0389 | 0.0148 | 0.0680 | 0.0352 | 0.0666 | 0.0291 | 0.0852 | 0.0452 | 0.7281 | 0.8731 | 0.0023 | 0.0054 | 0.0057 | 0.0075 | 0.0154 | 0.0299 | 0.0570 | 0.0680 | 0.1115 | 0.1497 | 0.1591 | 0.1844 | 0.1081 | 0.1163 | 0.1420 | 0.1306 | 0.3989 | 0.3082 | 0.0007 | 0.0032 | 0.0068 | 0.0241 | 0.0727 | 0.1106 | 0.0894 | 0.1272 | 0.5653 | 7 | 9 | 13 | 25 | 64 | 146 | 254 | 375 | 525 | 0.0542 | 24.53 | 5.282 | 0.4416 | 84546.7 | 50200000 | 34700000000 | 26800000000000 | 0.4917 | 0.1628 | 0.0917 | 0.0009 | 0.2762 | 0.0235 | 0.3457 | 0.2055 | 0.1342 | 0.1964 | 0.0753 | 0.2196 | 0.0473 | 0.1648 | 0.0208 | 0.0975 | 0.0068 | 0.0592 | 0.0019 | 0.0325 | 0.0001 | 0.0000 | 0.0004 | 0.0004 | 0.0005 | 0.0007 | 0.0084 | 0.0060 | 0.0544 | 0.0468 | 0.0935 | 0.0840 | 0.0596 | 0.0515 | 0.0953 | 0.0815 | 0.6877 | 0.7291 | 0.0001 | 0.0001 | 0.0001 | 0.0004 | 0.0013 | 0.0016 | 0.0121 | 0.0199 | 0.0750 | 0.0811 | 0.1193 | 0.1295 | 0.0741 | 0.0859 | 0.1155 | 0.1244 | 0.6026 | 0.5571 | 0.0002 | 0.0002 | 0.0006 | 0.0101 | 0.0639 | 0.1058 | 0.0698 | 0.1080 | 0.6414 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 321 | 840 | | 426 | 368 | 95.5 | 47.70 | 697.86 | 488.70 | 32 | 42 | 60 | 77 | 96 | 112 | 127 | 143 | 162 | 0.4701 | 173 | 0.664 | 93.61 | 19.80 | 1 | 0.5915 | 252 | 0.0030 | 67.57 | 5.878 | 0.1356 | 11384.7 | 1540000 | 222000000 | 33700000000 | 0.2891 | 0.3236 | 0.0000 | 0.0000 | 0.0000 | 0.0052 | 0.1616 | 0.0000 | 0.1919 | 0.0155 | 0.2121 | 0.1503 | 0.1515 | 0.2591 | 0.2020 | 0.1295 | 0.0404 | 0.1969 | 0.0404 | 0.2435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0077 | 0.0032 | 0.0575 | 0.0583 | 0.0996 | 0.0841 | 0.0421 | 0.0388 | 0.0613 | 0.0680 | 0.7318 | 0.7476 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0062 | 0.0000 | 0.0247 | 0.0517 | 0.0802 | 0.0862 | 0.1049 | 0.1897 | 0.0988 | 0.1207 | 0.1420 | 0.1034 | 0.5432 | 0.4483 | 0.0000 | 0.0000 | 0.0000 | 0.0140 | 0.0698 | 0.0930 | 0.0512 | 0.0884 | 0.6837 | 135 | 270 | 399 | 510 | 616 | 717 | 852 | 1036 | 1456 | 0.0038 | 170.10 | 5.726 | 0.1849 | 725176.0 | 955000000 | 1470000000000 | 2.5E+15 | 0.4289 | 0.2015 | 0.0465 | 0.0000 | 0.1860 | 0.0120 | 0.2558 | 0.0663 | 0.1279 | 0.1205 | 0.1047 | 0.2651 | 0.1395 | 0.2108 | 0.0814 | 0.1566 | 0.0581 | 0.0904 | 0.0000 | 0.0783 | 0.0050 | 0.0000 | 0.0300 | 0.0000 | 0.0550 | 0.0405 | 0.0750 | 0.0526 | 0.1250 | 0.1579 | 0.1600 | 0.1741 | 0.1700 | 0.1660 | 0.1450 | 0.1296 | 0.2350 | 0.2794 | 0.0439 | 0.0000 | 0.0351 | 0.0000 | 0.0263 | 0.0864 | 0.1228 | 0.0864 | 0.1053 | 0.1605 | 0.2193 | 0.1235 | 0.0965 | 0.1111 | 0.0965 | 0.1358 | 0.2544 | 0.2963 | 0.0132 | 0.0395 | 0.0724 | 0.0921 | 0.1645 | 0.1579 | 0.1382 | 0.0921 | 0.2303 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 129 | 102 | | 853 | 4631 | 107.8 | 32.30 | 12.53 | 4.15 | 72 | 80 | 87 | 94 | 102 | 110 | 119 | 135 | 159 | 0.1162 | 538 | 1.081 | 46.87 | 17.49 | 1 | 0.1489 | 127 | 0.0142 | 2.79 | 4.517 | 0.4969 | 12655.4 | 1610000 | 221000000 | 32300000000 | 0.4358 | 0.2021 | 0.0024 | 0.0000 | 0.0024 | 0.0028 | 0.0097 | 0.0014 | 0.0607 | 0.0185 | 0.1602 | 0.0541 | 0.1990 | 0.1223 | 0.1553 | 0.0896 | 0.1456 | 0.1181 | 0.2646 | 0.5932 | 0.0017 | 0.0000 | 0.0017 | 0.0012 | 0.0066 | 0.0000 | 0.0249 | 0.0111 | 0.0731 | 0.0382 | 0.0897 | 0.0764 | 0.0797 | 0.0480 | 0.1030 | 0.0640 | 0.6196 | 0.7611 | 0.0000 | 0.0000 | 0.0105 | 0.0000 | 0.0105 | 0.0092 | 0.0316 | 0.0734 | 0.0947 | 0.1376 | 0.1211 | 0.1835 | 0.0789 | 0.1193 | 0.1421 | 0.1835 | 0.5105 | 0.2936 | 0.0055 | 0.0055 | 0.0110 | 0.0440 | 0.0769 | 0.1044 | 0.1181 | 0.1209 | 0.5137 | 7 | 9 | 10 | 11 | 12 | 13 | 14 | 16 | 18 | 0.0078 | 26.38 | 5.307 | 0.2385 | 174.1 | 2649.31 | 43748.6 | 779909 | 0.5184 | 0.1395 | 0.0240 | 0.0003 | 0.0831 | 0.0035 | 0.1717 | 0.0122 | 0.2432 | 0.0319 | 0.2538 | 0.0856 | 0.1461 | 0.1297 | 0.0621 | 0.2158 | 0.0130 | 0.3053 | 0.0030 | 0.2158 | 0.0040 | 0.0000 | 0.0242 | 0.0010 | 0.0646 | 0.0043 | 0.1036 | 0.0183 | 0.1480 | 0.0550 | 0.1705 | 0.0815 | 0.1609 | 0.1399 | 0.1487 | 0.2628 | 0.1755 | 0.4372 | 0.1595 | 0.2552 | 0.1673 | 0.1849 | 0.1399 | 0.1094 | 0.1145 | 0.1484 | 0.1243 | 0.1198 | 0.0920 | 0.0964 | 0.0841 | 0.0495 | 0.0626 | 0.0339 | 0.0558 | 0.0026 | 0.0301 | 0.0872 | 0.1248 | 0.1442 | 0.1442 | 0.1368 | 0.1113 | 0.1076 | 0.1136 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 374 | 827 | | 538 | 5755 | 91.8 | 48.44 | 171.54 | 297.95 | 29 | 40 | 57 | 74 | 89 | 101 | 116 | 140 | 161 | 0.0895 | 515 | 1.275 | 31.62 | 12.17 | 2 | 0.1543 | 83 | 0.0025 | 70.15 | 6.080 | 0.1560 | 10772.9 | 1460000 | 216000000 | 34000000000 | 0.3272 | 0.2735 | 0.0000 | 0.0000 | 0.0282 | 0.0000 | 0.1338 | 0.0000 | 0.1901 | 0.0198 | 0.1620 | 0.1581 | 0.1268 | 0.1937 | 0.1479 | 0.1621 | 0.1056 | 0.1581 | 0.1056 | 0.3083 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0031 | 0.0131 | 0.0800 | 0.0551 | 0.0985 | 0.0866 | 0.0431 | 0.0525 | 0.1138 | 0.0840 | 0.6585 | 0.7087 | 0.0000 | 0.0000 | 0.0000 | 0.0156 | 0.0055 | 0.0000 | 0.0383 | 0.0156 | 0.1038 | 0.1328 | 0.1038 | 0.1016 | 0.1093 | 0.1016 | 0.1421 | 0.1328 | 0.4973 | 0.5000 | 0.0000 | 0.0000 | 0.0078 | 0.0389 | 0.0661 | 0.1128 | 0.0973 | 0.1128 | 0.5642 | 17 | 19 | 20 | 22 | 25 | 35 | 92 | 249 | 645 | 0.1812 | 27.53 | 3.742 | 0.6466 | 118185.0 | 112000000 | 119000000000 | 139000000000000 | 0.7250 | 0.0477 | 0.0600 | 0.0080 | 0.2240 | 0.0282 | 0.3600 | 0.1690 | 0.1600 | 0.1932 | 0.0920 | 0.2012 | 0.0480 | 0.1469 | 0.0240 | 0.1066 | 0.0240 | 0.0624 | 0.0080 | 0.0845 | 0.0000 | 0.0000 | 0.0007 | 0.0006 | 0.0020 | 0.0012 | 0.0231 | 0.0168 | 0.0909 | 0.0895 | 0.1324 | 0.1111 | 0.0856 | 0.0847 | 0.1232 | 0.1219 | 0.5422 | 0.5742 | 0.0000 | 0.0000 | 0.0047 | 0.0060 | 0.0087 | 0.0146 | 0.0379 | 0.0368 | 0.0883 | 0.0856 | 0.1270 | 0.1336 | 0.1017 | 0.0967 | 0.1222 | 0.1182 | 0.5095 | 0.5086 | 0.0000 | 0.0000 | 0.0086 | 0.0281 | 0.0944 | 0.1354 | 0.0929 | 0.1218 | 0.5187 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 640 | 505 | | 7321 | 15664 | 132.9 | 24.36 | 203.28 | 114.00 | 103 | 113 | 120 | 126 | 131 | 137 | 144 | 152 | 164 | 0.0602 | 943 | 0.886 | 94.20 | 24.52 | 1 | 0.0328 | 240 | 0.0034 | 11.56 | 6.014 | 0.3124 | 18256.5 | 2590000 | 379000000 | 57200000000 | 0.4249 | 0.2269 | 0.0000 | 0.0001 | 0.0000 | 0.0000 | 0.0031 | 0.0001 | 0.0107 | 0.0008 | 0.0451 | 0.0126 | 0.0959 | 0.0291 | 0.1106 | 0.0302 | 0.1519 | 0.0455 | 0.5827 | 0.8815 | 0.0000 | 0.0001 | 0.0000 | 0.0000 | 0.0013 | 0.0001 | 0.0041 | 0.0006 | 0.0213 | 0.0113 | 0.0421 | 0.0206 | 0.0458 | 0.0151 | 0.0696 | 0.0214 | 0.8160 | 0.9308 | 0.0083 | 0.0311 | 0.0156 | 0.0497 | 0.0353 | 0.0807 | 0.1048 | 0.1491 | 0.1566 | 0.2609 | 0.1940 | 0.1677 | 0.1193 | 0.0621 | 0.1421 | 0.1429 | 0.2241 | 0.0559 | 0.0026 | 0.0048 | 0.0145 | 0.0318 | 0.0705 | 0.1166 | 0.1066 | 0.1362 | 0.5163 | 66 | 100 | 130 | 159 | 188 | 221 | 256 | 298 | 361 | 0.0013 | 36.57 | 7.039 | 0.2500 | 54319.8 | 17300000 | 6280000000 | 2520000000000 | 0.5417 | 0.1374 | 0.0116 | 0.0006 | 0.0610 | 0.0034 | 0.1692 | 0.0206 | 0.1815 | 0.0547 | 0.2027 | 0.1259 | 0.1727 | 0.1917 | 0.1056 | 0.1593 | 0.0625 | 0.1770 | 0.0330 | 0.2666 | 0.0005 | 0.0002 | 0.0016 | 0.0004 | 0.0064 | 0.0030 | 0.0191 | 0.0101 | 0.0584 | 0.0425 | 0.1194 | 0.0871 | 0.0931 | 0.0697 | 0.1203 | 0.1000 | 0.5810 | 0.6870 | 0.0025 | 0.0036 | 0.0078 | 0.0101 | 0.0228 | 0.0258 | 0.0457 | 0.0697 | 0.1071 | 0.1403 | 0.1660 | 0.1930 | 0.1333 | 0.1409 | 0.1465 | 0.1479 | 0.3682 | 0.2686 | 0.0013 | 0.0039 | 0.0104 | 0.0303 | 0.0787 | 0.1477 | 0.1131 | 0.1412 | 0.4735 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 559 | | 1919 | 9291 | 297.6 | 53.29 | 250.19 | 260.24 | 215 | 254 | 277 | 295 | 308 | 321 | 332 | 343 | 357 | 0.0677 | 629 | 1.003 | 87.82 | 29.21 | 1 | 0.1178 | 226 | 0.0022 | 14.65 | 6.307 | 0.2647 | 91416.6 | 28800000 | 9250000000 | 3020000000000 | 0.3763 | 0.2593 | 0.0007 | 0.0005 | 0.0007 | 0.0000 | 0.0021 | 0.0005 | 0.0084 | 0.0011 | 0.0439 | 0.0183 | 0.0927 | 0.0458 | 0.0836 | 0.0188 | 0.1157 | 0.0285 | 0.6523 | 0.8864 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0012 | 0.0011 | 0.0265 | 0.0183 | 0.0468 | 0.0458 | 0.0302 | 0.0188 | 0.0406 | 0.0285 | 0.8548 | 0.8864 | 0.0105 | 0.0000 | 0.0000 | 0.0000 | 0.1000 | 0.0000 | 0.1263 | 0.0000 | 0.1842 | 0.0000 | 0.1842 | 0.0000 | 0.1421 | 0.0000 | 0.1421 | 0.0000 | 0.1105 | 0.0000 | 0.0000 | 0.0009 | 0.0036 | 0.0217 | 0.0407 | 0.0724 | 0.0733 | 0.1005 | 0.6869 | 21 | 33 | 58 | 95 | 149 | 231 | 329 | 452 | 626 | 0.0131 | 45.83 | 6.311 | 0.3810 | 130308.0 | 91600000 | 76700000000 | 72600000000000 | 0.6100 | 0.0919 | 0.0351 | 0.0025 | 0.1174 | 0.0114 | 0.2999 | 0.0602 | 0.1555 | 0.1210 | 0.1525 | 0.1916 | 0.1254 | 0.2020 | 0.0582 | 0.1432 | 0.0381 | 0.1249 | 0.0181 | 0.1432 | 0.0000 | 0.0000 | 0.0007 | 0.0006 | 0.0030 | 0.0017 | 0.0128 | 0.0101 | 0.0650 | 0.0509 | 0.0904 | 0.0798 | 0.0623 | 0.0612 | 0.1067 | 0.0878 | 0.6591 | 0.7078 | 0.0000 | 0.0004 | 0.0020 | 0.0011 | 0.0059 | 0.0061 | 0.0203 | 0.0318 | 0.0764 | 0.0842 | 0.1147 | 0.1248 | 0.0869 | 0.1083 | 0.1275 | 0.1348 | 0.5664 | 0.5084 | 0.0003 | 0.0011 | 0.0046 | 0.0154 | 0.0733 | 0.0984 | 0.0821 | 0.1146 | 0.6102 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 767 | 375 | | 10994 | 36702 | 317.2 | 66.33 | 88.78 | 117.60 | 238 | 259 | 276 | 292 | 309 | 327 | 346 | 373 | 410 | 0.0385 | 1412 | 0.777 | 113.02 | 23.02 | 1 | 0.0226 | 249 | 0.0006 | 70.27 | 7.726 | 0.1479 | 104984.0 | 36300000 | 13000000000 | 4880000000000 | 0.4228 | 0.2250 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0001 | 0.0125 | 0.0008 | 0.0612 | 0.0134 | 0.1259 | 0.0305 | 0.1295 | 0.0324 | 0.1666 | 0.0567 | 0.4994 | 0.8660 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0062 | 0.0003 | 0.0265 | 0.0088 | 0.0510 | 0.0177 | 0.0541 | 0.0124 | 0.0766 | 0.0239 | 0.7828 | 0.9370 | 0.0031 | 0.0102 | 0.0078 | 0.0225 | 0.0225 | 0.0758 | 0.0628 | 0.1250 | 0.1313 | 0.1557 | 0.1763 | 0.1475 | 0.1104 | 0.1025 | 0.1423 | 0.1270 | 0.3433 | 0.2336 | 0.0010 | 0.0030 | 0.0062 | 0.0294 | 0.0726 | 0.1184 | 0.1031 | 0.1345 | 0.5318 | 10 | 12 | 14 | 19 | 32 | 55 | 97 | 156 | 255 | 0.0788 | 13.52 | 4.639 | 0.5538 | 21712.5 | 8010000 | 3800000000 | 2180000000000 | 0.4103 | 0.2154 | 0.0637 | 0.0009 | 0.2390 | 0.0098 | 0.3525 | 0.1068 | 0.1643 | 0.1924 | 0.0959 | 0.2534 | 0.0480 | 0.2004 | 0.0216 | 0.1040 | 0.0113 | 0.0742 | 0.0037 | 0.0580 | 0.0002 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0012 | 0.0109 | 0.0097 | 0.0639 | 0.0507 | 0.0964 | 0.0843 | 0.0715 | 0.0616 | 0.1087 | 0.0931 | 0.6473 | 0.6989 | 0.0002 | 0.0004 | 0.0011 | 0.0016 | 0.0034 | 0.0043 | 0.0175 | 0.0189 | 0.0814 | 0.0927 | 0.1222 | 0.1338 | 0.0853 | 0.0887 | 0.1273 | 0.1253 | 0.5616 | 0.5343 | 0.0001 | 0.0004 | 0.0016 | 0.0110 | 0.0724 | 0.1147 | 0.0774 | 0.1169 | 0.6055 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 750 | 676 | | 11146 | 21855 | 106.6 | 28.30 | 189.51 | 171.91 | 74 | 83 | 90 | 97 | 103 | 110 | 118 | 128 | 143 | 0.0573 | 1252 | 0.886 | 106.10 | 29.53 | 1 | 0.0241 | 269 | 0.0014 | 32.07 | 6.896 | 0.2173 | 12166.0 | 1490000 | 200000000 | 29600000000 | 0.4458 | 0.2114 | 0.0009 | 0.0000 | 0.0026 | 0.0003 | 0.0096 | 0.0013 | 0.0300 | 0.0038 | 0.0861 | 0.0213 | 0.1508 | 0.0508 | 0.1608 | 0.0587 | 0.1819 | 0.0839 | 0.3773 | 0.7799 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0039 | 0.0003 | 0.0101 | 0.0021 | 0.0393 | 0.0133 | 0.0634 | 0.0258 | 0.0685 | 0.0231 | 0.0980 | 0.0366 | 0.7155 | 0.8988 | 0.0018 | 0.0088 | 0.0088 | 0.0164 | 0.0226 | 0.0582 | 0.0647 | 0.1239 | 0.1317 | 0.2010 | 0.1714 | 0.1795 | 0.1183 | 0.1163 | 0.1423 | 0.1277 | 0.3383 | 0.1681 | 0.0014 | 0.0032 | 0.0116 | 0.0332 | 0.0812 | 0.1162 | 0.1018 | 0.1287 | 0.5226 | 16 | 35 | 67 | 103 | 142 | 190 | 249 | 320 | 433 | 0.0120 | 37.39 | 6.296 | 0.3650 | 65463.6 | 30100000 | 16600000000 | 10400000000000 | 0.5497 | 0.1277 | 0.0358 | 0.0017 | 0.1299 | 0.0109 | 0.2197 | 0.0768 | 0.1613 | 0.1097 | 0.1616 | 0.1610 | 0.1328 | 0.1855 | 0.0738 | 0.1385 | 0.0543 | 0.1308 | 0.0308 | 0.1851 | 0.0000 | 0.0000 | 0.0012 | 0.0012 | 0.0025 | 0.0022 | 0.0135 | 0.0090 | 0.0598 | 0.0462 | 0.1069 | 0.0836 | 0.0781 | 0.0656 | 0.1195 | 0.1003 | 0.6185 | 0.6919 | 0.0006 | 0.0002 | 0.0018 | 0.0023 | 0.0045 | 0.0088 | 0.0267 | 0.0326 | 0.0915 | 0.1031 | 0.1477 | 0.1742 | 0.1100 | 0.1208 | 0.1446 | 0.1560 | 0.4726 | 0.4020 | 0.0002 | 0.0008 | 0.0031 | 0.0184 | 0.0746 | 0.1276 | 0.0976 | 0.1359 | 0.5419 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 819 | 837 | | 4077 | 7402 | 164.0 | 45.49 | 281.51 | 208.60 | 106 | 126 | 139 | 150 | 161 | 172 | 185 | 201 | 225 | 0.0809 | 599 | 0.666 | 68.59 | 22.56 | 2 | 0.0518 | 211 | 0.0013 | 30.19 | 6.879 | 0.2104 | 28976.0 | 5470000 | 1100000000 | 232000000000 | 0.4785 | 0.1795 | 0.0028 | 0.0000 | 0.0032 | 0.0006 | 0.0065 | 0.0020 | 0.0341 | 0.0061 | 0.1138 | 0.0314 | 0.1876 | 0.0802 | 0.1618 | 0.0709 | 0.1834 | 0.0994 | 0.3069 | 0.7095 | 0.0006 | 0.0000 | 0.0010 | 0.0003 | 0.0019 | 0.0005 | 0.0081 | 0.0026 | 0.0430 | 0.0195 | 0.0783 | 0.0445 | 0.0608 | 0.0306 | 0.0935 | 0.0458 | 0.7126 | 0.8562 | 0.0043 | 0.0113 | 0.0185 | 0.0226 | 0.0120 | 0.0452 | 0.0663 | 0.1271 | 0.1261 | 0.1582 | 0.1815 | 0.2345 | 0.1239 | 0.1356 | 0.1424 | 0.0989 | 0.3250 | 0.1667 | 0.0015 | 0.0021 | 0.0072 | 0.0355 | 0.0762 | 0.1340 | 0.1061 | 0.1175 | 0.5198 | 41 | 86 | 136 | 190 | 247 | 308 | 370 | 448 | 564 | 0.0018 | 128.90 | 7.431 | 0.1991 | 122752.0 | 67400000 | 43400000000 | 31600000000000 | 0.5494 | 0.1250 | 0.0218 | 0.0004 | 0.1102 | 0.0047 | 0.2408 | 0.0505 | 0.1748 | 0.0920 | 0.1769 | 0.1749 | 0.1363 | 0.2080 | 0.0798 | 0.1531 | 0.0428 | 0.1385 | 0.0167 | 0.1778 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0011 | 0.0151 | 0.0089 | 0.0627 | 0.0498 | 0.1204 | 0.0924 | 0.0929 | 0.0759 | 0.1327 | 0.1043 | 0.5715 | 0.6676 | 0.0000 | 0.0020 | 0.0042 | 0.0036 | 0.0096 | 0.0137 | 0.0301 | 0.0493 | 0.1131 | 0.1301 | 0.1521 | 0.1876 | 0.1212 | 0.1256 | 0.1613 | 0.1520 | 0.4083 | 0.3360 | 0.0015 | 0.0024 | 0.0049 | 0.0182 | 0.0809 | 0.1469 | 0.1031 | 0.1338 | 0.5082 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 110 | 146 | | 3370 | 10890 | 147.0 | 47.54 | 205.95 | 210.52 | 96 | 109 | 120 | 130 | 141 | 152 | 166 | 184 | 210 | 0.0687 | 748 | 0.698 | 87.82 | 16.12 | 1 | 0.0591 | 199 | 0.0013 | 45.70 | 6.937 | 0.1972 | 23872.7 | 4240000 | 821000000 | 172000000000 | 0.4754 | 0.1834 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0213 | 0.0022 | 0.0640 | 0.0076 | 0.1469 | 0.0404 | 0.2133 | 0.0913 | 0.1633 | 0.0822 | 0.1664 | 0.1230 | 0.2176 | 0.6533 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0021 | 0.0003 | 0.0144 | 0.0026 | 0.0499 | 0.0204 | 0.0960 | 0.0459 | 0.0828 | 0.0328 | 0.1240 | 0.0548 | 0.6288 | 0.8431 | 0.0013 | 0.0000 | 0.0038 | 0.0233 | 0.0115 | 0.0465 | 0.0712 | 0.0930 | 0.1387 | 0.1964 | 0.2010 | 0.1783 | 0.1221 | 0.1163 | 0.1425 | 0.1370 | 0.3079 | 0.2093 | 0.0000 | 0.0026 | 0.0073 | 0.0389 | 0.0956 | 0.1404 | 0.1107 | 0.1325 | 0.4720 | 20 | 29 | 54 | 89 | 136 | 193 | 264 | 354 | 501 | 0.0118 | 65.86 | 6.461 | 0.3264 | 86732.2 | 51500000 | 38400000000 | 34300000000000 | 0.4942 | 0.1738 | 0.0577 | 0.0022 | 0.1982 | 0.0147 | 0.2589 | 0.0932 | 0.1590 | 0.1398 | 0.1250 | 0.1746 | 0.0895 | 0.1735 | 0.0643 | 0.1315 | 0.0348 | 0.1305 | 0.0126 | 0.1401 | 0.0006 | 0.0002 | 0.0021 | 0.0007 | 0.0027 | 0.0018 | 0.0144 | 0.0103 | 0.0681 | 0.0533 | 0.1264 | 0.0962 | 0.0930 | 0.0790 | 0.1328 | 0.1098 | 0.5599 | 0.6487 | 0.0006 | 0.0017 | 0.0011 | 0.0058 | 0.0108 | 0.0178 | 0.0354 | 0.0463 | 0.1058 | 0.1014 | 0.1580 | 0.1570 | 0.1044 | 0.1056 | 0.1298 | 0.1395 | 0.4541 | 0.4249 | 0.0000 | 0.0012 | 0.0063 | 0.0167 | 0.0951 | 0.1417 | 0.1103 | 0.1347 | 0.4942 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 824 | 149 | | 3095 | 1375 | 156.7 | 47.45 | 110.15 | 90.82 | 105 | 115 | 124 | 134 | 145 | 160 | 176 | 196 | 227 | 0.3382 | 465 | 1.062 | 83.41 | 29.00 | 1 | 0.0666 | 206 | 0.0014 | 36.35 | 6.808 | 0.1956 | 26798.4 | 4990000 | 1010000000 | 217000000000 | 0.4010 | 0.2369 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0164 | 0.0004 | 0.0622 | 0.0073 | 0.1630 | 0.0383 | 0.2209 | 0.0865 | 0.1773 | 0.0930 | 0.1651 | 0.1290 | 0.1937 | 0.6455 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0066 | 0.0003 | 0.0164 | 0.0033 | 0.0564 | 0.0210 | 0.0986 | 0.0440 | 0.0737 | 0.0367 | 0.1015 | 0.0660 | 0.6458 | 0.8286 | 0.0014 | 0.0026 | 0.0014 | 0.0104 | 0.0096 | 0.0181 | 0.0493 | 0.0907 | 0.1315 | 0.1684 | 0.1685 | 0.1813 | 0.1055 | 0.1192 | 0.1425 | 0.1684 | 0.3904 | 0.2409 | 0.0008 | 0.0000 | 0.0046 | 0.0245 | 0.0772 | 0.1376 | 0.1009 | 0.1223 | 0.5321 | 23 | 34 | 49 | 66 | 79 | 101 | 130 | 181 | 247 | 0.0068 | 27.40 | 5.667 | 0.3730 | 20376.5 | 5090000 | 1510000000 | 502000000000 | 0.4253 | 0.1878 | 0.0226 | 0.0041 | 0.1584 | 0.0225 | 0.2443 | 0.0736 | 0.1493 | 0.0920 | 0.1946 | 0.2086 | 0.1584 | 0.2658 | 0.0588 | 0.1411 | 0.0136 | 0.1022 | 0.0000 | 0.0900 | 0.0000 | 0.0000 | 0.0112 | 0.0048 | 0.0128 | 0.0060 | 0.0400 | 0.0290 | 0.1808 | 0.1351 | 0.2208 | 0.2268 | 0.1120 | 0.1218 | 0.1408 | 0.1375 | 0.2816 | 0.3390 | 0.0050 | 0.0118 | 0.0099 | 0.0147 | 0.0347 | 0.0265 | 0.0743 | 0.0588 | 0.1535 | 0.1971 | 0.2153 | 0.1971 | 0.0990 | 0.1088 | 0.1361 | 0.1412 | 0.2723 | 0.2441 | 0.0039 | 0.0137 | 0.0333 | 0.0412 | 0.1902 | 0.2039 | 0.1000 | 0.1294 | 0.2843 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 866 | 124 | | 7868 | 18298 | 509.3 | 103.27 | 71.24 | 63.85 | 380 | 418 | 450 | 475 | 502 | 530 | 561 | 596 | 645 | 0.0624 | 1141 | 1.024 | 98.60 | 36.00 | 1 | 0.0336 | 264 | 0.0007 | 43.87 | 7.460 | 0.1703 | 270039.0 | 149000000 | 85000000000 | 50300000000000 | 0.4294 | 0.2140 | 0.0004 | 0.0000 | 0.0011 | 0.0001 | 0.0029 | 0.0005 | 0.0116 | 0.0009 | 0.0506 | 0.0141 | 0.0958 | 0.0303 | 0.1076 | 0.0255 | 0.1326 | 0.0412 | 0.5975 | 0.8874 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0001 | 0.0044 | 0.0005 | 0.0218 | 0.0097 | 0.0421 | 0.0212 | 0.0456 | 0.0141 | 0.0611 | 0.0214 | 0.8231 | 0.9329 | 0.0015 | 0.0151 | 0.0115 | 0.0075 | 0.0137 | 0.0491 | 0.0634 | 0.0943 | 0.0977 | 0.1698 | 0.1504 | 0.1698 | 0.1107 | 0.1132 | 0.1427 | 0.1208 | 0.4084 | 0.2604 | 0.0005 | 0.0021 | 0.0061 | 0.0192 | 0.0541 | 0.0908 | 0.0842 | 0.1111 | 0.6320 | 12 | 20 | 32 | 44 | 56 | 67 | 82 | 103 | 155 | 0.0160 | 5.43 | 4.946 | 0.5259 | 9151.3 | 1720000 | 410000000 | 113000000000 | 0.3977 | 0.2161 | 0.0063 | 0.0014 | 0.0287 | 0.0034 | 0.0848 | 0.0127 | 0.1175 | 0.0402 | 0.1734 | 0.0962 | 0.1759 | 0.1181 | 0.1582 | 0.1348 | 0.1455 | 0.1664 | 0.1097 | 0.4269 | 0.0011 | 0.0006 | 0.0036 | 0.0013 | 0.0059 | 0.0046 | 0.0190 | 0.0127 | 0.0462 | 0.0332 | 0.0641 | 0.0471 | 0.0697 | 0.0516 | 0.0984 | 0.0760 | 0.6920 | 0.7730 | 0.0018 | 0.0028 | 0.0049 | 0.0062 | 0.0101 | 0.0130 | 0.0352 | 0.0370 | 0.0677 | 0.0795 | 0.0948 | 0.0956 | 0.0883 | 0.0857 | 0.1176 | 0.1134 | 0.5795 | 0.5667 | 0.0029 | 0.0063 | 0.0092 | 0.0245 | 0.0550 | 0.0789 | 0.0782 | 0.1114 | 0.6337 | ||
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1069 | 128 | | 2783 | 11256 | 51.7 | 18.54 | 103.66 | 116.84 | 30 | 35 | 40 | 45 | 50 | 54 | 60 | 67 | 78 | 0.0861 | 969 | 0.603 | 152.75 | 27.51 | 6 | 0.1347 | 375 | 0.0052 | 9.08 | 5.547 | 0.3491 | 3018.8 | 195743 | 13900000 | 1050000000 | 0.4330 | 0.1802 | 0.0026 | 0.0005 | 0.0071 | 0.0000 | 0.0556 | 0.0035 | 0.1412 | 0.0262 | 0.1571 | 0.0657 | 0.1986 | 0.1226 | 0.1297 | 0.1409 | 0.1262 | 0.1557 | 0.1818 | 0.4849 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0011 | 0.0017 | 0.0228 | 0.0132 | 0.0565 | 0.0405 | 0.1146 | 0.0653 | 0.0880 | 0.0690 | 0.1222 | 0.0860 | 0.5932 | 0.7243 | 0.0071 | 0.0025 | 0.0085 | 0.0354 | 0.0297 | 0.0303 | 0.0621 | 0.0581 | 0.1285 | 0.1465 | 0.1370 | 0.1641 | 0.1314 | 0.1237 | 0.1427 | 0.1717 | 0.3531 | 0.2677 | 0.0008 | 0.0000 | 0.0110 | 0.0432 | 0.0856 | 0.1540 | 0.1163 | 0.1406 | 0.4485 | 13 | 17 | 24 | 38 | 58 | 83 | 121 | 176 | 261 | 0.0237 | 15.67 | 5.256 | 0.4584 | 24394.3 | 8520000 | 3730000000 | 1900000000000 | 0.5135 | 0.1676 | 0.0460 | 0.0031 | 0.1957 | 0.0140 | 0.2492 | 0.0815 | 0.1672 | 0.1444 | 0.1530 | 0.1870 | 0.0962 | 0.1917 | 0.0552 | 0.1269 | 0.0268 | 0.1211 | 0.0109 | 0.1304 | 0.0004 | 0.0007 | 0.0020 | 0.0011 | 0.0080 | 0.0037 | 0.0214 | 0.0182 | 0.0764 | 0.0588 | 0.1256 | 0.1088 | 0.0857 | 0.0785 | 0.1129 | 0.1069 | 0.5677 | 0.6232 | 0.0021 | 0.0004 | 0.0030 | 0.0071 | 0.0118 | 0.0139 | 0.0300 | 0.0363 | 0.0919 | 0.0879 | 0.1475 | 0.1584 | 0.1001 | 0.0993 | 0.1186 | 0.1217 | 0.4948 | 0.4751 | 0.0005 | 0.0031 | 0.0065 | 0.0265 | 0.0749 | 0.1471 | 0.0884 | 0.1191 | 0.5339 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 976 | 627 | | 9507 | 15770 | 172.7 | 40.39 | 150.51 | 142.96 | 124 | 138 | 148 | 159 | 169 | 180 | 192 | 205 | 226 | 0.0652 | 1028 | 0.252 | 178.21 | 38.29 | 2 | 0.0807 | 767 | 0.0013 | 30.28 | 6.953 | 0.2069 | 31455.3 | 6030000 | 1210000000 | 255000000000 | 0.4791 | 0.1735 | 0.0005 | 0.0001 | 0.0012 | 0.0000 | 0.0054 | 0.0005 | 0.0209 | 0.0019 | 0.0790 | 0.0197 | 0.1482 | 0.0402 | 0.1609 | 0.0520 | 0.1854 | 0.0737 | 0.3985 | 0.8119 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0027 | 0.0001 | 0.0082 | 0.0004 | 0.0356 | 0.0131 | 0.0592 | 0.0224 | 0.0625 | 0.0227 | 0.0860 | 0.0360 | 0.7450 | 0.9053 | 0.0072 | 0.0075 | 0.0078 | 0.0226 | 0.0245 | 0.0395 | 0.0686 | 0.1598 | 0.1421 | 0.1692 | 0.1633 | 0.1805 | 0.1165 | 0.1297 | 0.1427 | 0.1147 | 0.3272 | 0.1767 | 0.0011 | 0.0022 | 0.0101 | 0.0314 | 0.0686 | 0.1188 | 0.1000 | 0.1331 | 0.5347 | 15 | 26 | 47 | 75 | 109 | 150 | 195 | 249 | 346 | 0.0111 | 36.23 | 6.317 | 0.3622 | 43089.9 | 16900000 | 8150000000 | 4520000000000 | 0.5500 | 0.1433 | 0.0300 | 0.0027 | 0.1203 | 0.0089 | 0.2106 | 0.0533 | 0.1413 | 0.1064 | 0.1498 | 0.1689 | 0.1341 | 0.1813 | 0.0903 | 0.1371 | 0.0662 | 0.1320 | 0.0577 | 0.2093 | 0.0005 | 0.0010 | 0.0013 | 0.0013 | 0.0051 | 0.0033 | 0.0142 | 0.0094 | 0.0556 | 0.0503 | 0.0990 | 0.0768 | 0.0770 | 0.0661 | 0.1045 | 0.0926 | 0.6428 | 0.6991 | 0.0008 | 0.0021 | 0.0025 | 0.0062 | 0.0081 | 0.0129 | 0.0272 | 0.0348 | 0.0805 | 0.0881 | 0.1303 | 0.1407 | 0.0956 | 0.1050 | 0.1222 | 0.1264 | 0.5327 | 0.4839 | 0.0003 | 0.0032 | 0.0054 | 0.0167 | 0.0715 | 0.1122 | 0.0858 | 0.1157 | 0.5891 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 118 | 415 | | 5291 | 13931 | 133.5 | 31.83 | 201.37 | 181.71 | 100 | 107 | 114 | 119 | 126 | 134 | 144 | 157 | 178 | 0.0743 | 1035 | 1.075 | 91.53 | 27.73 | 2 | 0.0433 | 229 | 0.0025 | 21.43 | 6.360 | 0.2445 | 18826.4 | 2820000 | 448000000 | 75800000000 | 0.4311 | 0.2131 | 0.0015 | 0.0000 | 0.0042 | 0.0000 | 0.0097 | 0.0006 | 0.0303 | 0.0025 | 0.0739 | 0.0239 | 0.1357 | 0.0482 | 0.1636 | 0.0458 | 0.2090 | 0.0658 | 0.3720 | 0.8132 | 0.0012 | 0.0000 | 0.0028 | 0.0000 | 0.0044 | 0.0000 | 0.0131 | 0.0009 | 0.0332 | 0.0117 | 0.0592 | 0.0263 | 0.0788 | 0.0152 | 0.1106 | 0.0243 | 0.6966 | 0.9216 | 0.0062 | 0.0078 | 0.0175 | 0.0337 | 0.0287 | 0.0285 | 0.0585 | 0.0933 | 0.1181 | 0.1917 | 0.1694 | 0.1839 | 0.1201 | 0.1503 | 0.1427 | 0.1554 | 0.3388 | 0.1554 | 0.0072 | 0.0031 | 0.0143 | 0.0371 | 0.0809 | 0.1314 | 0.1033 | 0.1404 | 0.4823 | 25 | 47 | 73 | 108 | 146 | 194 | 256 | 337 | 458 | 0.0034 | 64.02 | 6.918 | 0.3096 | 73564.5 | 36500000 | 22100000000 | 15400000000000 | 0.6227 | 0.0824 | 0.0134 | 0.0036 | 0.0711 | 0.0072 | 0.1619 | 0.0323 | 0.1753 | 0.0736 | 0.1984 | 0.1406 | 0.1681 | 0.1996 | 0.1071 | 0.1572 | 0.0644 | 0.1658 | 0.0403 | 0.2202 | 0.0011 | 0.0011 | 0.0023 | 0.0013 | 0.0063 | 0.0053 | 0.0173 | 0.0127 | 0.0541 | 0.0396 | 0.0851 | 0.0756 | 0.0699 | 0.0574 | 0.0977 | 0.0911 | 0.6663 | 0.7158 | 0.0014 | 0.0014 | 0.0032 | 0.0035 | 0.0083 | 0.0127 | 0.0236 | 0.0343 | 0.0730 | 0.0863 | 0.1137 | 0.1284 | 0.0955 | 0.1055 | 0.1286 | 0.1320 | 0.5528 | 0.4959 | 0.0017 | 0.0045 | 0.0102 | 0.0202 | 0.0633 | 0.0900 | 0.0787 | 0.1201 | 0.6112 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 232 | 638 | | 6254 | 5949 | 114.7 | 25.41 | 187.62 | 143.24 | 87 | 94 | 100 | 105 | 110 | 116 | 123 | 132 | 150 | 0.1308 | 778 | 0.961 | 106.23 | 31.32 | 1 | 0.0421 | 263 | 0.0034 | 14.14 | 6.046 | 0.2876 | 13792.0 | 1750000 | 233000000 | 32800000000 | 0.4648 | 0.1869 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0092 | 0.0003 | 0.0230 | 0.0024 | 0.0653 | 0.0177 | 0.1219 | 0.0491 | 0.1387 | 0.0346 | 0.1702 | 0.0694 | 0.4696 | 0.8265 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0003 | 0.0324 | 0.0105 | 0.0605 | 0.0277 | 0.0714 | 0.0137 | 0.0961 | 0.0290 | 0.7274 | 0.9189 | 0.0097 | 0.0198 | 0.0117 | 0.0074 | 0.0272 | 0.0272 | 0.0690 | 0.0743 | 0.1370 | 0.2030 | 0.1594 | 0.1807 | 0.1108 | 0.1436 | 0.1429 | 0.1337 | 0.3324 | 0.2104 | 0.0023 | 0.0109 | 0.0214 | 0.0436 | 0.1019 | 0.1320 | 0.1169 | 0.1421 | 0.4289 | 42 | 65 | 88 | 115 | 148 | 183 | 233 | 303 | 394 | 0.0021 | 69.90 | 6.913 | 0.2582 | 55713.5 | 21700000 | 10100000000 | 5300000000000 | 0.5779 | 0.0961 | 0.0346 | 0.0023 | 0.1508 | 0.0121 | 0.2315 | 0.0680 | 0.1585 | 0.1253 | 0.1537 | 0.1524 | 0.1162 | 0.1729 | 0.0836 | 0.1356 | 0.0500 | 0.1212 | 0.0211 | 0.2102 | 0.0017 | 0.0003 | 0.0017 | 0.0017 | 0.0069 | 0.0050 | 0.0247 | 0.0182 | 0.0897 | 0.0636 | 0.1357 | 0.1151 | 0.1103 | 0.0851 | 0.1454 | 0.1258 | 0.4838 | 0.5854 | 0.0016 | 0.0047 | 0.0064 | 0.0034 | 0.0112 | 0.0229 | 0.0508 | 0.0518 | 0.1086 | 0.1312 | 0.1825 | 0.1783 | 0.1215 | 0.1285 | 0.1429 | 0.1406 | 0.3745 | 0.3385 | 0.0004 | 0.0017 | 0.0120 | 0.0322 | 0.1043 | 0.1550 | 0.1245 | 0.1426 | 0.4272 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 659 | 414 | | 3454 | 6251 | 174.4 | 39.87 | 242.89 | 154.32 | 131 | 143 | 152 | 159 | 167 | 177 | 189 | 204 | 226 | 0.1125 | 703 | 1.107 | 91.24 | 26.63 | 1 | 0.0617 | 213 | 0.0019 | 25.62 | 6.561 | 0.2385 | 32018.5 | 6210000 | 1280000000 | 278000000000 | 0.4520 | 0.2052 | 0.0004 | 0.0000 | 0.0009 | 0.0003 | 0.0088 | 0.0006 | 0.0206 | 0.0022 | 0.0697 | 0.0235 | 0.1434 | 0.0423 | 0.1298 | 0.0346 | 0.1684 | 0.0676 | 0.4579 | 0.8289 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0003 | 0.0052 | 0.0003 | 0.0351 | 0.0160 | 0.0762 | 0.0274 | 0.0616 | 0.0189 | 0.1043 | 0.0335 | 0.7155 | 0.9036 | 0.0017 | 0.0154 | 0.0134 | 0.0205 | 0.0185 | 0.0308 | 0.0487 | 0.1026 | 0.1546 | 0.1231 | 0.1748 | 0.1846 | 0.1294 | 0.1538 | 0.1429 | 0.0923 | 0.3160 | 0.2769 | 0.0007 | 0.0033 | 0.0080 | 0.0361 | 0.0916 | 0.1424 | 0.0989 | 0.1404 | 0.4786 | 79 | 111 | 142 | 170 | 206 | 251 | 299 | 360 | 457 | 0.0013 | 68.96 | 7.135 | 0.2323 | 82803.2 | 35900000 | 18500000000 | 10900000000000 | 0.5283 | 0.1292 | 0.0088 | 0.0007 | 0.0739 | 0.0045 | 0.1684 | 0.0182 | 0.1611 | 0.0636 | 0.1859 | 0.1374 | 0.1720 | 0.2049 | 0.1061 | 0.1528 | 0.0820 | 0.1545 | 0.0417 | 0.2633 | 0.0003 | 0.0002 | 0.0027 | 0.0005 | 0.0066 | 0.0040 | 0.0217 | 0.0160 | 0.0714 | 0.0488 | 0.1042 | 0.0905 | 0.0819 | 0.0726 | 0.1153 | 0.1014 | 0.5959 | 0.6660 | 0.0041 | 0.0042 | 0.0051 | 0.0035 | 0.0128 | 0.0229 | 0.0389 | 0.0660 | 0.1064 | 0.1313 | 0.1529 | 0.1771 | 0.1233 | 0.1188 | 0.1483 | 0.1465 | 0.4082 | 0.3299 | 0.0004 | 0.0031 | 0.0100 | 0.0268 | 0.0824 | 0.1234 | 0.1031 | 0.1388 | 0.5121 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 324 | 200 | | 9267 | 28546 | 136.9 | 41.75 | 161.87 | 233.98 | 86 | 99 | 112 | 124 | 135 | 146 | 158 | 172 | 193 | 0.0455 | 1300 | 0.914 | 69.01 | 19.70 | 6 | 0.0181 | 168 | 0.0013 | 24.49 | 6.895 | 0.2332 | 20479.4 | 3300000 | 567000000 | 103000000000 | 0.4196 | 0.2164 | 0.0018 | 0.0000 | 0.0058 | 0.0004 | 0.0076 | 0.0017 | 0.0306 | 0.0073 | 0.1008 | 0.0279 | 0.1517 | 0.0559 | 0.1639 | 0.0691 | 0.1899 | 0.0994 | 0.3480 | 0.7382 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0018 | 0.0004 | 0.0088 | 0.0035 | 0.0321 | 0.0139 | 0.0490 | 0.0251 | 0.0522 | 0.0285 | 0.0722 | 0.0388 | 0.7809 | 0.8897 | 0.0043 | 0.0081 | 0.0086 | 0.0070 | 0.0241 | 0.0252 | 0.0455 | 0.0916 | 0.0769 | 0.1370 | 0.1327 | 0.1631 | 0.1078 | 0.1269 | 0.1430 | 0.1511 | 0.4570 | 0.2900 | 0.0011 | 0.0051 | 0.0058 | 0.0210 | 0.0568 | 0.0917 | 0.0790 | 0.1085 | 0.6310 | 20 | 25 | 32 | 42 | 59 | 88 | 146 | 248 | 465 | 0.0337 | 41.47 | 5.283 | 0.5159 | 80948.0 | 65000000 | 65600000000 | 76000000000000 | 0.5258 | 0.1466 | 0.0551 | 0.0017 | 0.1968 | 0.0211 | 0.2532 | 0.1230 | 0.1516 | 0.1351 | 0.1376 | 0.1940 | 0.0880 | 0.1858 | 0.0596 | 0.1152 | 0.0384 | 0.1031 | 0.0199 | 0.1210 | 0.0003 | 0.0001 | 0.0003 | 0.0004 | 0.0036 | 0.0018 | 0.0190 | 0.0156 | 0.0709 | 0.0590 | 0.1046 | 0.0925 | 0.0709 | 0.0629 | 0.1037 | 0.0968 | 0.6266 | 0.6709 | 0.0006 | 0.0008 | 0.0014 | 0.0019 | 0.0072 | 0.0074 | 0.0231 | 0.0271 | 0.0831 | 0.0907 | 0.1334 | 0.1460 | 0.0842 | 0.0925 | 0.1238 | 0.1209 | 0.5433 | 0.5125 | 0.0008 | 0.0026 | 0.0043 | 0.0227 | 0.0776 | 0.1148 | 0.0780 | 0.1182 | 0.5810 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 919 | 384 | | 3864 | 10644 | 549.9 | 111.66 | 119.69 | 118.07 | 401 | 445 | 482 | 515 | 547 | 581 | 614 | 651 | 699 | 0.0750 | 798 | 1.029 | 90.48 | 35.85 | 1 | 0.0663 | 256 | 0.0007 | 70.72 | 7.491 | 0.1370 | 314839.0 | 187000000 | 115000000000 | 72500000000000 | 0.4423 | 0.2000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0000 | 0.0131 | 0.0027 | 0.0668 | 0.0158 | 0.1439 | 0.0363 | 0.1447 | 0.0328 | 0.1681 | 0.0507 | 0.4596 | 0.8617 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0051 | 0.0021 | 0.0277 | 0.0136 | 0.0621 | 0.0288 | 0.0535 | 0.0207 | 0.0701 | 0.0298 | 0.7804 | 0.9050 | 0.0029 | 0.0519 | 0.0114 | 0.0390 | 0.0157 | 0.0390 | 0.0672 | 0.1818 | 0.1502 | 0.2338 | 0.1788 | 0.1948 | 0.1288 | 0.1169 | 0.1431 | 0.0519 | 0.3019 | 0.0909 | 0.0000 | 0.0010 | 0.0037 | 0.0199 | 0.0659 | 0.1141 | 0.0795 | 0.1141 | 0.6018 | 11 | 15 | 23 | 44 | 81 | 122 | 165 | 219 | 293 | 0.0192 | 16.46 | 5.675 | 0.4317 | 28266.0 | 8580000 | 3000000000 | 1160000000000 | 0.4622 | 0.1810 | 0.0320 | 0.0021 | 0.1652 | 0.0111 | 0.2654 | 0.0848 | 0.1446 | 0.1330 | 0.1611 | 0.2072 | 0.1002 | 0.1734 | 0.0666 | 0.1199 | 0.0411 | 0.1273 | 0.0238 | 0.1413 | 0.0004 | 0.0004 | 0.0002 | 0.0004 | 0.0026 | 0.0020 | 0.0100 | 0.0065 | 0.0573 | 0.0464 | 0.0915 | 0.0770 | 0.0713 | 0.0525 | 0.1045 | 0.0919 | 0.6622 | 0.7230 | 0.0003 | 0.0006 | 0.0019 | 0.0016 | 0.0054 | 0.0048 | 0.0200 | 0.0279 | 0.0764 | 0.0901 | 0.1300 | 0.1487 | 0.0978 | 0.0983 | 0.1230 | 0.1376 | 0.5451 | 0.4903 | 0.0005 | 0.0016 | 0.0023 | 0.0137 | 0.0615 | 0.1121 | 0.0896 | 0.1246 | 0.5942 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1037 | 548 | | 6893 | 19634 | 196.4 | 53.42 | 59.21 | 59.92 | 132 | 150 | 164 | 177 | 190 | 203 | 219 | 239 | 270 | 0.0562 | 1104 | 1.139 | 106.17 | 38.83 | 1 | 0.0396 | 273 | 0.0009 | 48.97 | 7.272 | 0.1760 | 41433.9 | 9350000 | 2250000000 | 573000000000 | 0.4801 | 0.1819 | 0.0008 | 0.0000 | 0.0027 | 0.0003 | 0.0176 | 0.0008 | 0.0295 | 0.0045 | 0.1140 | 0.0308 | 0.1710 | 0.0578 | 0.1497 | 0.0610 | 0.1702 | 0.0896 | 0.3445 | 0.7552 | 0.0004 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0002 | 0.0060 | 0.0012 | 0.0441 | 0.0158 | 0.0768 | 0.0292 | 0.0676 | 0.0257 | 0.1060 | 0.0467 | 0.6977 | 0.8812 | 0.0027 | 0.0063 | 0.0033 | 0.0110 | 0.0154 | 0.0267 | 0.0642 | 0.0879 | 0.1338 | 0.1586 | 0.1893 | 0.2198 | 0.1097 | 0.1224 | 0.1431 | 0.1429 | 0.3385 | 0.2245 | 0.0019 | 0.0013 | 0.0079 | 0.0282 | 0.0904 | 0.1431 | 0.1028 | 0.1352 | 0.4891 | 11 | 20 | 27 | 36 | 45 | 56 | 68 | 85 | 113 | 0.0115 | 9.46 | 5.188 | 0.4764 | 7095.4 | 1710000 | 681000000 | 349000000000 | 0.5533 | 0.1205 | 0.0095 | 0.0030 | 0.0478 | 0.0089 | 0.1372 | 0.0199 | 0.1794 | 0.0504 | 0.1937 | 0.1192 | 0.1744 | 0.1608 | 0.1277 | 0.1622 | 0.0842 | 0.1835 | 0.0462 | 0.2921 | 0.0014 | 0.0014 | 0.0025 | 0.0030 | 0.0103 | 0.0063 | 0.0254 | 0.0159 | 0.0611 | 0.0437 | 0.0923 | 0.0664 | 0.0846 | 0.0698 | 0.1181 | 0.1017 | 0.6043 | 0.6918 | 0.0040 | 0.0052 | 0.0059 | 0.0136 | 0.0158 | 0.0236 | 0.0370 | 0.0536 | 0.0902 | 0.0983 | 0.1230 | 0.1323 | 0.1097 | 0.1162 | 0.1320 | 0.1328 | 0.4824 | 0.4244 | 0.0026 | 0.0071 | 0.0163 | 0.0301 | 0.0751 | 0.0993 | 0.0984 | 0.1252 | 0.5459 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 713 | 522 | | 16894 | 27359 | 277.6 | 52.05 | 216.35 | 215.57 | 208 | 237 | 256 | 269 | 281 | 294 | 306 | 320 | 341 | 0.0538 | 1471 | 1.091 | 103.16 | 31.06 | 2 | 0.0146 | 247 | 0.0019 | 13.94 | 6.613 | 0.2949 | 79797.3 | 23600000 | 7150000000 | 2220000000000 | 0.4393 | 0.2062 | 0.0005 | 0.0001 | 0.0011 | 0.0000 | 0.0033 | 0.0002 | 0.0092 | 0.0012 | 0.0381 | 0.0103 | 0.0669 | 0.0200 | 0.0670 | 0.0172 | 0.0957 | 0.0278 | 0.7182 | 0.9233 | 0.0001 | 0.0001 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0036 | 0.0009 | 0.0175 | 0.0093 | 0.0294 | 0.0173 | 0.0273 | 0.0120 | 0.0360 | 0.0204 | 0.8849 | 0.9400 | 0.0059 | 0.0000 | 0.0174 | 0.0000 | 0.0329 | 0.0000 | 0.0567 | 0.0000 | 0.1025 | 0.0000 | 0.1459 | 0.0000 | 0.1189 | 0.0000 | 0.1432 | 0.0000 | 0.3765 | 0.0000 | 0.0017 | 0.0028 | 0.0050 | 0.0176 | 0.0419 | 0.0771 | 0.0726 | 0.0997 | 0.6818 | 21 | 32 | 52 | 93 | 142 | 205 | 283 | 380 | 530 | 0.0112 | 32.03 | 6.315 | 0.3897 | 93278.7 | 53900000 | 36900000000 | 28400000000000 | 0.5194 | 0.1468 | 0.0368 | 0.0022 | 0.1715 | 0.0112 | 0.2748 | 0.0782 | 0.1614 | 0.1448 | 0.1334 | 0.1933 | 0.0945 | 0.1853 | 0.0577 | 0.1275 | 0.0408 | 0.1189 | 0.0291 | 0.1384 | 0.0004 | 0.0005 | 0.0011 | 0.0010 | 0.0036 | 0.0028 | 0.0148 | 0.0107 | 0.0581 | 0.0512 | 0.1064 | 0.0873 | 0.0753 | 0.0672 | 0.1096 | 0.0986 | 0.6307 | 0.6805 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0066 | 0.0087 | 0.0278 | 0.0330 | 0.0781 | 0.0932 | 0.1289 | 0.1454 | 0.1017 | 0.1011 | 0.1260 | 0.1267 | 0.5291 | 0.4877 | 0.0007 | 0.0016 | 0.0048 | 0.0183 | 0.0725 | 0.1147 | 0.0880 | 0.1182 | 0.5812 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 307 | 653 | | 10385 | 21337 | 574.1 | 114.46 | 155.18 | 135.73 | 433 | 473 | 505 | 535 | 564 | 596 | 628 | 670 | 733 | 0.0486 | 1036 | 0.577 | 103.02 | 13.04 | 1 | 0.0206 | 214 | 0.0007 | 50.52 | 7.494 | 0.1652 | 342696.0 | 212000000 | 136000000000 | 90600000000000 | 0.4477 | 0.1993 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0000 | 0.0114 | 0.0003 | 0.0529 | 0.0143 | 0.1183 | 0.0275 | 0.1255 | 0.0275 | 0.1535 | 0.0489 | 0.5362 | 0.8814 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0000 | 0.0053 | 0.0001 | 0.0241 | 0.0099 | 0.0493 | 0.0168 | 0.0533 | 0.0122 | 0.0720 | 0.0203 | 0.7946 | 0.9407 | 0.0023 | 0.0176 | 0.0082 | 0.0265 | 0.0164 | 0.0676 | 0.0614 | 0.1088 | 0.1392 | 0.2118 | 0.1766 | 0.2000 | 0.1094 | 0.1294 | 0.1433 | 0.1235 | 0.3433 | 0.1147 | 0.0008 | 0.0010 | 0.0049 | 0.0246 | 0.0722 | 0.1181 | 0.0958 | 0.1311 | 0.5515 | 25 | 42 | 64 | 88 | 118 | 150 | 191 | 249 | 337 | 0.0077 | 23.32 | 5.939 | 0.3643 | 42503.4 | 16400000 | 8080000000 | 4790000000000 | 0.5282 | 0.1429 | 0.0347 | 0.0014 | 0.1391 | 0.0079 | 0.2389 | 0.0792 | 0.1810 | 0.1231 | 0.1607 | 0.1736 | 0.1170 | 0.1882 | 0.0714 | 0.1466 | 0.0353 | 0.1335 | 0.0219 | 0.1463 | 0.0005 | 0.0002 | 0.0011 | 0.0004 | 0.0042 | 0.0024 | 0.0233 | 0.0140 | 0.0793 | 0.0638 | 0.1263 | 0.0985 | 0.1017 | 0.0802 | 0.1398 | 0.1307 | 0.5240 | 0.6098 | 0.0009 | 0.0039 | 0.0053 | 0.0039 | 0.0117 | 0.0141 | 0.0449 | 0.0589 | 0.1098 | 0.1287 | 0.1665 | 0.1769 | 0.1228 | 0.1268 | 0.1550 | 0.1577 | 0.3832 | 0.3291 | 0.0010 | 0.0024 | 0.0071 | 0.0342 | 0.0973 | 0.1484 | 0.1159 | 0.1555 | 0.4382 |