High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 995 | 506 | | 7348 | 13304 | 328.1 | 66.27 | 48.85 | 74.47 | 255 | 274 | 288 | 301 | 315 | 331 | 351 | 380 | 424 | 0.0735 | 978 | 1.205 | 109.42 | 42.19 | 1 | 0.0378 | 278 | 0.0012 | 31.53 | 7.021 | 0.2102 | 112039.0 | 39900000 | 14800000000 | 5730000000000 | 0.4011 | 0.2457 | 0.0002 | 0.0001 | 0.0018 | 0.0000 | 0.0031 | 0.0004 | 0.0125 | 0.0010 | 0.0478 | 0.0179 | 0.0907 | 0.0300 | 0.1047 | 0.0257 | 0.1396 | 0.0390 | 0.5996 | 0.8857 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0000 | 0.0049 | 0.0004 | 0.0251 | 0.0127 | 0.0451 | 0.0174 | 0.0530 | 0.0121 | 0.0729 | 0.0176 | 0.7965 | 0.9398 | 0.0025 | 0.0027 | 0.0075 | 0.0107 | 0.0207 | 0.0160 | 0.0456 | 0.0587 | 0.0994 | 0.1440 | 0.1135 | 0.1627 | 0.0911 | 0.1253 | 0.1284 | 0.1733 | 0.4913 | 0.3067 | 0.0010 | 0.0036 | 0.0095 | 0.0381 | 0.0733 | 0.1167 | 0.0877 | 0.1023 | 0.5678 | 5 | 6 | 8 | 10 | 15 | 25 | 44 | 78 | 142 | 0.0775 | 3.22 | 3.468 | 0.5712 | 7931.8 | 2060000 | 684000000 | 264000000000 | 0.5693 | 0.1073 | 0.0459 | 0.0072 | 0.1741 | 0.0189 | 0.2799 | 0.0762 | 0.1677 | 0.1610 | 0.1496 | 0.2239 | 0.0823 | 0.1774 | 0.0545 | 0.1385 | 0.0406 | 0.1048 | 0.0053 | 0.0920 | 0.0000 | 0.0012 | 0.0024 | 0.0006 | 0.0019 | 0.0035 | 0.0167 | 0.0141 | 0.0618 | 0.0575 | 0.0992 | 0.0834 | 0.0703 | 0.0653 | 0.1081 | 0.1073 | 0.6396 | 0.6672 | 0.0015 | 0.0003 | 0.0012 | 0.0037 | 0.0042 | 0.0058 | 0.0184 | 0.0299 | 0.0802 | 0.0807 | 0.1100 | 0.1028 | 0.0699 | 0.0879 | 0.1115 | 0.1153 | 0.6031 | 0.5736 | 0.0003 | 0.0008 | 0.0043 | 0.0184 | 0.0714 | 0.1044 | 0.0703 | 0.1164 | 0.6138 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 292 | 776 | | 6777 | 12524 | 325.6 | 51.91 | 172.85 | 222.30 | 258 | 277 | 296 | 311 | 323 | 337 | 352 | 369 | 393 | 0.0787 | 986 | 1.019 | 135.34 | 41.01 | 1 | 0.0484 | 328 | 0.0017 | 16.93 | 6.629 | 0.2646 | 108700.0 | 37200000 | 13000000000 | 4670000000000 | 0.3905 | 0.2545 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0036 | 0.0001 | 0.0131 | 0.0003 | 0.0300 | 0.0124 | 0.0571 | 0.0234 | 0.0742 | 0.0142 | 0.0991 | 0.0285 | 0.7210 | 0.9211 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0000 | 0.0071 | 0.0001 | 0.0167 | 0.0114 | 0.0295 | 0.0193 | 0.0326 | 0.0106 | 0.0443 | 0.0171 | 0.8660 | 0.9414 | 0.0057 | 0.0000 | 0.0114 | 0.0000 | 0.0341 | 0.0000 | 0.0994 | 0.0000 | 0.0994 | 0.0000 | 0.1605 | 0.0000 | 0.1179 | 0.0000 | 0.1264 | 0.0000 | 0.3452 | 0.0000 | 0.0015 | 0.0034 | 0.0073 | 0.0208 | 0.0531 | 0.0784 | 0.0815 | 0.1227 | 0.6313 | 14 | 16 | 19 | 25 | 51 | 113 | 215 | 343 | 515 | 0.0450 | 24.78 | 5.251 | 0.4914 | 79286.9 | 49200000 | 36500000000 | 31300000000000 | 0.4891 | 0.1521 | 0.0682 | 0.0006 | 0.2302 | 0.0144 | 0.3264 | 0.1428 | 0.1949 | 0.1888 | 0.1084 | 0.2199 | 0.0560 | 0.1929 | 0.0097 | 0.1180 | 0.0049 | 0.0760 | 0.0012 | 0.0466 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0015 | 0.0099 | 0.0101 | 0.0578 | 0.0482 | 0.0893 | 0.0778 | 0.0562 | 0.0523 | 0.0885 | 0.0782 | 0.6971 | 0.7317 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0023 | 0.0032 | 0.0138 | 0.0193 | 0.0706 | 0.0776 | 0.1115 | 0.1144 | 0.0701 | 0.0761 | 0.0996 | 0.1129 | 0.6310 | 0.5957 | 0.0000 | 0.0000 | 0.0012 | 0.0129 | 0.0628 | 0.1014 | 0.0584 | 0.0960 | 0.6673 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 862 | 60 | | 536 | 8372 | 94.9 | 38.62 | 150.81 | 294.15 | 38 | 55 | 70 | 85 | 97 | 109 | 121 | 135 | 146 | 0.0688 | 576 | 0.456 | 105.65 | 21.93 | 2 | 0.7705 | 413 | 0.0025 | 45.30 | 6.078 | 0.1747 | 10500.4 | 1270000 | 163000000 | 21700000000 | 0.3490 | 0.2577 | 0.0000 | 0.0032 | 0.0057 | 0.0000 | 0.0345 | 0.0000 | 0.1149 | 0.0097 | 0.1782 | 0.0968 | 0.1782 | 0.1452 | 0.1322 | 0.1161 | 0.1379 | 0.1613 | 0.2184 | 0.4677 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0137 | 0.0024 | 0.0521 | 0.0471 | 0.0493 | 0.0659 | 0.0548 | 0.0329 | 0.0740 | 0.0776 | 0.7562 | 0.7741 | 0.0000 | 0.0000 | 0.0052 | 0.0000 | 0.0052 | 0.0087 | 0.0209 | 0.0435 | 0.0995 | 0.1130 | 0.0785 | 0.1130 | 0.1099 | 0.1217 | 0.1152 | 0.1739 | 0.5654 | 0.4261 | 0.0000 | 0.0000 | 0.0035 | 0.0142 | 0.0745 | 0.0816 | 0.0780 | 0.0957 | 0.6525 | 15 | 18 | 20 | 22 | 25 | 32 | 64 | 197 | 482 | 0.1543 | 30.36 | 3.816 | 0.6306 | 109258.0 | 124000000 | 171000000000 | 266000000000000 | 0.6017 | 0.0867 | 0.1678 | 0.0032 | 0.3557 | 0.0852 | 0.2550 | 0.2981 | 0.1040 | 0.2618 | 0.0570 | 0.1467 | 0.0336 | 0.1073 | 0.0201 | 0.0442 | 0.0067 | 0.0331 | 0.0000 | 0.0205 | 0.0010 | 0.0004 | 0.0025 | 0.0018 | 0.0029 | 0.0031 | 0.0152 | 0.0161 | 0.0678 | 0.0629 | 0.1130 | 0.0915 | 0.0683 | 0.0683 | 0.1170 | 0.1071 | 0.6123 | 0.6488 | 0.0006 | 0.0006 | 0.0012 | 0.0006 | 0.0069 | 0.0056 | 0.0242 | 0.0311 | 0.0806 | 0.0840 | 0.1163 | 0.1319 | 0.0996 | 0.0989 | 0.1232 | 0.1319 | 0.5475 | 0.5152 | 0.0011 | 0.0021 | 0.0037 | 0.0144 | 0.0880 | 0.1077 | 0.0859 | 0.1189 | 0.5781 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 831 | 627 | | 22430 | 35732 | 126.0 | 38.62 | 252.74 | 227.53 | 82 | 95 | 104 | 113 | 121 | 131 | 142 | 157 | 179 | 0.0532 | 1901 | 0.880 | 73.43 | 20.81 | 2 | 0.0089 | 200 | 0.0017 | 21.99 | 6.753 | 0.2609 | 17379.7 | 2600000 | 417000000 | 71800000000 | 0.4412 | 0.2102 | 0.0006 | 0.0001 | 0.0021 | 0.0002 | 0.0088 | 0.0011 | 0.0346 | 0.0052 | 0.1045 | 0.0291 | 0.1823 | 0.0693 | 0.1643 | 0.0693 | 0.1767 | 0.0997 | 0.3261 | 0.7259 | 0.0002 | 0.0001 | 0.0008 | 0.0001 | 0.0022 | 0.0002 | 0.0101 | 0.0018 | 0.0357 | 0.0141 | 0.0709 | 0.0319 | 0.0688 | 0.0258 | 0.0917 | 0.0432 | 0.7197 | 0.8826 | 0.0034 | 0.0054 | 0.0050 | 0.0100 | 0.0140 | 0.0284 | 0.0533 | 0.0888 | 0.0998 | 0.1568 | 0.1659 | 0.2106 | 0.1164 | 0.1172 | 0.1451 | 0.1426 | 0.3972 | 0.2402 | 0.0011 | 0.0034 | 0.0087 | 0.0271 | 0.0720 | 0.1160 | 0.1006 | 0.1196 | 0.5516 | 16 | 33 | 75 | 138 | 204 | 273 | 343 | 432 | 576 | 0.0082 | 55.93 | 6.842 | 0.3237 | 115644.0 | 68100000 | 47400000000 | 37300000000000 | 0.5184 | 0.1555 | 0.0294 | 0.0010 | 0.1132 | 0.0078 | 0.2146 | 0.0613 | 0.1758 | 0.0954 | 0.1640 | 0.1647 | 0.1397 | 0.1993 | 0.0852 | 0.1472 | 0.0476 | 0.1393 | 0.0304 | 0.1840 | 0.0000 | 0.0002 | 0.0006 | 0.0007 | 0.0018 | 0.0015 | 0.0125 | 0.0070 | 0.0472 | 0.0386 | 0.0990 | 0.0797 | 0.0795 | 0.0590 | 0.1063 | 0.0906 | 0.6532 | 0.7227 | 0.0006 | 0.0013 | 0.0027 | 0.0029 | 0.0077 | 0.0109 | 0.0241 | 0.0340 | 0.0806 | 0.1011 | 0.1356 | 0.1539 | 0.1094 | 0.1178 | 0.1359 | 0.1438 | 0.5033 | 0.4344 | 0.0003 | 0.0016 | 0.0049 | 0.0169 | 0.0624 | 0.1189 | 0.0930 | 0.1202 | 0.5819 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 834 | 433 | | 10028 | 23515 | 170.4 | 45.07 | 251.81 | 223.41 | 116 | 130 | 142 | 154 | 167 | 180 | 195 | 212 | 231 | 0.0643 | 1511 | 0.433 | 138.81 | 20.40 | 4 | 0.0343 | 344 | 0.0006 | 58.13 | 7.696 | 0.1518 | 31076.2 | 6010000 | 1230000000 | 261000000000 | 0.4626 | 0.2012 | 0.0014 | 0.0001 | 0.0014 | 0.0000 | 0.0051 | 0.0010 | 0.0350 | 0.0070 | 0.1108 | 0.0315 | 0.1699 | 0.0658 | 0.1503 | 0.0658 | 0.1738 | 0.0971 | 0.3522 | 0.7316 | 0.0008 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0007 | 0.0127 | 0.0044 | 0.0411 | 0.0206 | 0.0636 | 0.0401 | 0.0541 | 0.0301 | 0.0732 | 0.0469 | 0.7527 | 0.8573 | 0.0016 | 0.0064 | 0.0036 | 0.0242 | 0.0121 | 0.0382 | 0.0395 | 0.1057 | 0.0999 | 0.1643 | 0.1386 | 0.1771 | 0.1185 | 0.1414 | 0.1350 | 0.1210 | 0.4512 | 0.2217 | 0.0013 | 0.0027 | 0.0055 | 0.0224 | 0.0554 | 0.0952 | 0.0829 | 0.1036 | 0.6310 | 27 | 65 | 104 | 142 | 188 | 246 | 318 | 410 | 550 | 0.0043 | 51.61 | 6.756 | 0.3199 | 113315.0 | 70500000 | 54700000000 | 49800000000000 | 0.5106 | 0.1551 | 0.0197 | 0.0009 | 0.0972 | 0.0050 | 0.2185 | 0.0351 | 0.1851 | 0.0833 | 0.1744 | 0.1635 | 0.1413 | 0.2193 | 0.0821 | 0.1599 | 0.0479 | 0.1407 | 0.0337 | 0.1922 | 0.0004 | 0.0003 | 0.0007 | 0.0007 | 0.0030 | 0.0032 | 0.0179 | 0.0117 | 0.0615 | 0.0449 | 0.0961 | 0.0795 | 0.0799 | 0.0637 | 0.0995 | 0.0868 | 0.6409 | 0.7092 | 0.0008 | 0.0013 | 0.0027 | 0.0038 | 0.0078 | 0.0110 | 0.0324 | 0.0428 | 0.0867 | 0.1042 | 0.1373 | 0.1566 | 0.0965 | 0.1074 | 0.1356 | 0.1445 | 0.5003 | 0.4284 | 0.0004 | 0.0017 | 0.0054 | 0.0273 | 0.0740 | 0.1165 | 0.0851 | 0.1169 | 0.5726 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 297 | 552 | | 14385 | 28437 | 82.4 | 25.65 | 78.88 | 67.92 | 54 | 61 | 67 | 72 | 78 | 84 | 92 | 102 | 118 | 0.0619 | 1760 | 0.262 | 166.21 | 32.56 | 3 | 0.0482 | 693 | 0.0019 | 19.35 | 6.626 | 0.2629 | 7444.0 | 736986 | 79600000 | 9310000000 | 0.4815 | 0.1870 | 0.0021 | 0.0003 | 0.0065 | 0.0003 | 0.0131 | 0.0021 | 0.0495 | 0.0068 | 0.1160 | 0.0333 | 0.1694 | 0.0768 | 0.1624 | 0.0699 | 0.1801 | 0.1101 | 0.3009 | 0.7002 | 0.0009 | 0.0001 | 0.0024 | 0.0002 | 0.0052 | 0.0010 | 0.0160 | 0.0027 | 0.0436 | 0.0170 | 0.0742 | 0.0391 | 0.0712 | 0.0313 | 0.0969 | 0.0550 | 0.6896 | 0.8537 | 0.0030 | 0.0071 | 0.0075 | 0.0071 | 0.0157 | 0.0308 | 0.0392 | 0.0711 | 0.1000 | 0.1257 | 0.1440 | 0.1814 | 0.1217 | 0.1209 | 0.1491 | 0.1375 | 0.4199 | 0.3183 | 0.0030 | 0.0033 | 0.0113 | 0.0296 | 0.0612 | 0.1057 | 0.0936 | 0.1170 | 0.5753 | 13 | 21 | 32 | 44 | 58 | 75 | 98 | 130 | 177 | 0.0288 | 3.28 | 4.562 | 0.5810 | 10835.9 | 2010000 | 449000000 | 114000000000 | 0.4815 | 0.2042 | 0.0179 | 0.0044 | 0.0831 | 0.0084 | 0.1602 | 0.0296 | 0.1876 | 0.0792 | 0.1946 | 0.1523 | 0.1540 | 0.1942 | 0.1033 | 0.1555 | 0.0667 | 0.1609 | 0.0325 | 0.2154 | 0.0015 | 0.0018 | 0.0051 | 0.0029 | 0.0095 | 0.0074 | 0.0231 | 0.0180 | 0.0558 | 0.0481 | 0.0860 | 0.0817 | 0.0704 | 0.0668 | 0.0931 | 0.0878 | 0.6555 | 0.6854 | 0.0035 | 0.0026 | 0.0057 | 0.0037 | 0.0118 | 0.0131 | 0.0292 | 0.0330 | 0.0623 | 0.0748 | 0.1026 | 0.1123 | 0.0901 | 0.1017 | 0.1112 | 0.1253 | 0.5837 | 0.5335 | 0.0017 | 0.0054 | 0.0113 | 0.0279 | 0.0579 | 0.0968 | 0.0744 | 0.1004 | 0.6242 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 431 | 339 | | 3943 | 10483 | 650.4 | 93.20 | 77.12 | 134.86 | 524 | 578 | 611 | 637 | 655 | 676 | 697 | 725 | 765 | 0.0630 | 660 | 1.066 | 99.30 | 32.65 | 1 | 0.0621 | 245 | 0.0013 | 29.21 | 6.926 | 0.2389 | 431670.0 | 292000000 | 201000000000 | 140000000000000 | 0.4337 | 0.2092 | 0.0006 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0043 | 0.0003 | 0.0239 | 0.0147 | 0.0347 | 0.0234 | 0.0340 | 0.0127 | 0.0534 | 0.0226 | 0.8476 | 0.9264 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0003 | 0.0148 | 0.0147 | 0.0235 | 0.0234 | 0.0179 | 0.0127 | 0.0277 | 0.0226 | 0.9140 | 0.9264 | 0.0065 | 0.0000 | 0.0065 | 0.0000 | 0.0226 | 0.0000 | 0.0355 | 0.0000 | 0.1000 | 0.0000 | 0.0871 | 0.0000 | 0.1065 | 0.0000 | 0.1290 | 0.0000 | 0.5065 | 0.0000 | 0.0000 | 0.0038 | 0.0072 | 0.0191 | 0.0401 | 0.0558 | 0.0615 | 0.0873 | 0.7252 | 6 | 8 | 9 | 11 | 14 | 22 | 53 | 125 | 238 | 0.1380 | 10.00 | 3.574 | 0.6077 | 24132.5 | 11700000 | 7110000000 | 4930000000000 | 0.4308 | 0.2239 | 0.0546 | 0.0060 | 0.1513 | 0.0313 | 0.2122 | 0.0625 | 0.1912 | 0.1159 | 0.1639 | 0.1915 | 0.1261 | 0.1935 | 0.0630 | 0.1381 | 0.0315 | 0.1190 | 0.0063 | 0.1421 | 0.0010 | 0.0000 | 0.0017 | 0.0015 | 0.0024 | 0.0033 | 0.0102 | 0.0118 | 0.0453 | 0.0386 | 0.0572 | 0.0477 | 0.0437 | 0.0443 | 0.0670 | 0.0641 | 0.7716 | 0.7887 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0020 | 0.0017 | 0.0113 | 0.0139 | 0.0577 | 0.0582 | 0.0658 | 0.0747 | 0.0516 | 0.0595 | 0.0791 | 0.0860 | 0.7313 | 0.7059 | 0.0004 | 0.0000 | 0.0015 | 0.0127 | 0.0470 | 0.0601 | 0.0548 | 0.0660 | 0.7576 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1118 | 571 | | 8114 | 11473 | 287.2 | 51.13 | 167.28 | 160.52 | 216 | 244 | 261 | 276 | 288 | 301 | 314 | 330 | 353 | 0.0825 | 946 | 0.972 | 44.55 | 15.65 | 1 | 0.0148 | 120 | 0.0020 | 14.93 | 6.529 | 0.2976 | 85117.2 | 26000000 | 8120000000 | 2600000000000 | 0.4373 | 0.2063 | 0.0005 | 0.0000 | 0.0015 | 0.0001 | 0.0027 | 0.0005 | 0.0121 | 0.0011 | 0.0320 | 0.0115 | 0.0585 | 0.0247 | 0.0605 | 0.0158 | 0.0827 | 0.0277 | 0.7495 | 0.9185 | 0.0003 | 0.0000 | 0.0003 | 0.0001 | 0.0010 | 0.0005 | 0.0049 | 0.0009 | 0.0130 | 0.0100 | 0.0228 | 0.0207 | 0.0186 | 0.0103 | 0.0277 | 0.0182 | 0.9114 | 0.9393 | 0.0075 | 0.0000 | 0.0197 | 0.0000 | 0.0254 | 0.0000 | 0.0630 | 0.0000 | 0.1006 | 0.0000 | 0.1410 | 0.0000 | 0.1194 | 0.0000 | 0.1391 | 0.0000 | 0.3844 | 0.0000 | 0.0017 | 0.0038 | 0.0094 | 0.0183 | 0.0428 | 0.0657 | 0.0729 | 0.0940 | 0.6914 | 14 | 20 | 33 | 56 | 109 | 178 | 247 | 321 | 407 | 0.0262 | 16.95 | 5.600 | 0.4608 | 53749.5 | 21300000 | 9500000000 | 4610000000000 | 0.5388 | 0.1195 | 0.0204 | 0.0036 | 0.0844 | 0.0071 | 0.2027 | 0.0554 | 0.2124 | 0.0996 | 0.1858 | 0.1765 | 0.1449 | 0.1957 | 0.0853 | 0.1425 | 0.0427 | 0.1367 | 0.0213 | 0.1828 | 0.0002 | 0.0002 | 0.0004 | 0.0000 | 0.0021 | 0.0010 | 0.0084 | 0.0088 | 0.0392 | 0.0312 | 0.0742 | 0.0636 | 0.0517 | 0.0429 | 0.0751 | 0.0700 | 0.7487 | 0.7823 | 0.0007 | 0.0000 | 0.0005 | 0.0016 | 0.0047 | 0.0066 | 0.0145 | 0.0172 | 0.0499 | 0.0620 | 0.0929 | 0.1039 | 0.0689 | 0.0823 | 0.0990 | 0.1175 | 0.6690 | 0.6089 | 0.0010 | 0.0008 | 0.0017 | 0.0109 | 0.0468 | 0.0801 | 0.0606 | 0.0887 | 0.7093 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 125 | 813 | | 4044 | 8852 | 602.6 | 91.52 | 41.19 | 63.75 | 467 | 546 | 581 | 603 | 621 | 637 | 653 | 670 | 697 | 0.0916 | 811 | 0.861 | 103.18 | 25.63 | 4 | 0.0601 | 243 | 0.0019 | 32.85 | 6.649 | 0.2422 | 371488.0 | 233000000 | 149000000000 | 95900000000000 | 0.4344 | 0.2018 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0008 | 0.0262 | 0.0168 | 0.0455 | 0.0300 | 0.0385 | 0.0173 | 0.0691 | 0.0297 | 0.8172 | 0.9055 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0008 | 0.0201 | 0.0167 | 0.0321 | 0.0289 | 0.0201 | 0.0157 | 0.0338 | 0.0282 | 0.8928 | 0.9097 | 0.0279 | 0.0000 | 0.0391 | 0.0000 | 0.0615 | 0.1429 | 0.1006 | 0.2857 | 0.1006 | 0.2857 | 0.1564 | 0.2857 | 0.1229 | 0.0000 | 0.0950 | 0.0000 | 0.2961 | 0.0000 | 0.0008 | 0.0021 | 0.0062 | 0.0181 | 0.0402 | 0.0743 | 0.0812 | 0.0952 | 0.6820 | 9 | 11 | 14 | 16 | 19 | 24 | 32 | 45 | 88 | 0.0559 | 3.74 | 3.856 | 0.6364 | 5760.6 | 1520000 | 505000000 | 191000000000 | 0.4879 | 0.1680 | 0.0222 | 0.0179 | 0.0677 | 0.0335 | 0.0812 | 0.0288 | 0.1141 | 0.0594 | 0.1460 | 0.0957 | 0.1470 | 0.0868 | 0.1692 | 0.1094 | 0.1335 | 0.1627 | 0.1190 | 0.4059 | 0.0058 | 0.0099 | 0.0173 | 0.0192 | 0.0142 | 0.0128 | 0.0242 | 0.0271 | 0.0468 | 0.0434 | 0.0560 | 0.0449 | 0.0629 | 0.0545 | 0.0844 | 0.0813 | 0.6884 | 0.7067 | 0.0032 | 0.0069 | 0.0153 | 0.0122 | 0.0159 | 0.0130 | 0.0312 | 0.0298 | 0.0503 | 0.0519 | 0.0751 | 0.0833 | 0.0649 | 0.0596 | 0.0808 | 0.0795 | 0.6635 | 0.6639 | 0.0049 | 0.0113 | 0.0157 | 0.0300 | 0.0458 | 0.0679 | 0.0684 | 0.0915 | 0.6644 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1011 | 503 | | 8099 | 27715 | 207.4 | 49.29 | 90.32 | 133.45 | 151 | 164 | 175 | 187 | 199 | 212 | 228 | 248 | 276 | 0.0437 | 1212 | 1.109 | 152.01 | 45.19 | 2 | 0.0436 | 353 | 0.0011 | 36.08 | 7.089 | 0.1990 | 45423.4 | 10500000 | 2560000000 | 657000000000 | 0.4089 | 0.2364 | 0.0004 | 0.0000 | 0.0023 | 0.0001 | 0.0071 | 0.0004 | 0.0235 | 0.0021 | 0.0760 | 0.0188 | 0.1336 | 0.0422 | 0.1525 | 0.0391 | 0.1806 | 0.0611 | 0.4239 | 0.8362 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0001 | 0.0108 | 0.0006 | 0.0290 | 0.0107 | 0.0546 | 0.0216 | 0.0625 | 0.0137 | 0.0784 | 0.0235 | 0.7599 | 0.9297 | 0.0031 | 0.0101 | 0.0081 | 0.0067 | 0.0219 | 0.0236 | 0.0663 | 0.0809 | 0.1006 | 0.1720 | 0.1644 | 0.1585 | 0.1294 | 0.1282 | 0.1413 | 0.1619 | 0.3650 | 0.2580 | 0.0019 | 0.0022 | 0.0111 | 0.0259 | 0.0674 | 0.1078 | 0.1033 | 0.1236 | 0.5567 | 7 | 8 | 10 | 11 | 15 | 35 | 93 | 181 | 284 | 0.1964 | 12.37 | 4.050 | 0.6366 | 25966.7 | 10500000 | 5130000000 | 2920000000000 | 0.4760 | 0.1582 | 0.0839 | 0.0025 | 0.2737 | 0.0194 | 0.3606 | 0.1699 | 0.1380 | 0.2452 | 0.0745 | 0.2308 | 0.0467 | 0.1602 | 0.0182 | 0.0849 | 0.0044 | 0.0541 | 0.0000 | 0.0330 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0003 | 0.0003 | 0.0065 | 0.0072 | 0.0442 | 0.0379 | 0.0776 | 0.0649 | 0.0515 | 0.0468 | 0.0806 | 0.0673 | 0.7388 | 0.7756 | 0.0000 | 0.0001 | 0.0003 | 0.0006 | 0.0004 | 0.0007 | 0.0094 | 0.0113 | 0.0554 | 0.0601 | 0.1006 | 0.1144 | 0.0720 | 0.0756 | 0.1022 | 0.1029 | 0.6597 | 0.6343 | 0.0001 | 0.0000 | 0.0006 | 0.0064 | 0.0501 | 0.0888 | 0.0621 | 0.0936 | 0.6982 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 828 | 731 | | 4916 | 17078 | 344.5 | 49.98 | 70.06 | 109.17 | 278 | 302 | 316 | 330 | 344 | 358 | 374 | 391 | 410 | 0.0440 | 752 | 0.700 | 121.80 | 29.61 | 2 | 0.0728 | 358 | 0.0032 | 8.09 | 6.021 | 0.3596 | 121208.0 | 43500000 | 15900000000 | 5900000000000 | 0.4249 | 0.2173 | 0.0002 | 0.0000 | 0.0015 | 0.0000 | 0.0045 | 0.0000 | 0.0067 | 0.0000 | 0.0270 | 0.0128 | 0.0399 | 0.0214 | 0.0394 | 0.0128 | 0.0789 | 0.0218 | 0.8018 | 0.9312 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0027 | 0.0000 | 0.0144 | 0.0128 | 0.0229 | 0.0214 | 0.0200 | 0.0128 | 0.0328 | 0.0185 | 0.9062 | 0.9345 | 0.0187 | 1.0000 | 0.0258 | 0.0000 | 0.0328 | 0.0000 | 0.0562 | 0.0000 | 0.1007 | 0.0000 | 0.1499 | 0.0000 | 0.1288 | 0.0000 | 0.1241 | 0.0000 | 0.3630 | 0.0000 | 0.0021 | 0.0041 | 0.0062 | 0.0144 | 0.0299 | 0.0533 | 0.0545 | 0.0685 | 0.7671 | 6 | 8 | 10 | 11 | 14 | 26 | 60 | 123 | 221 | 0.1196 | 5.30 | 3.437 | 0.5812 | 16825.5 | 6090000 | 2810000000 | 1590000000000 | 0.3847 | 0.2364 | 0.0327 | 0.0062 | 0.1401 | 0.0166 | 0.2424 | 0.0916 | 0.2139 | 0.1211 | 0.1718 | 0.1868 | 0.1149 | 0.2002 | 0.0516 | 0.1454 | 0.0263 | 0.1174 | 0.0063 | 0.1148 | 0.0000 | 0.0005 | 0.0006 | 0.0010 | 0.0023 | 0.0019 | 0.0083 | 0.0103 | 0.0391 | 0.0317 | 0.0712 | 0.0567 | 0.0463 | 0.0437 | 0.0805 | 0.0695 | 0.7518 | 0.7849 | 0.0000 | 0.0000 | 0.0009 | 0.0013 | 0.0021 | 0.0033 | 0.0145 | 0.0170 | 0.0532 | 0.0625 | 0.0907 | 0.0938 | 0.0628 | 0.0780 | 0.0937 | 0.1001 | 0.6822 | 0.6441 | 0.0004 | 0.0002 | 0.0032 | 0.0122 | 0.0464 | 0.0780 | 0.0622 | 0.0900 | 0.7075 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1197 | 726 | | 3699 | 9192 | 137.4 | 44.39 | 37.17 | 36.11 | 98 | 107 | 113 | 119 | 127 | 135 | 146 | 160 | 187 | 0.0926 | 851 | 1.180 | 107.28 | 41.01 | 1 | 0.0746 | 276 | 0.0024 | 30.51 | 6.416 | 0.2449 | 20843.7 | 3610000 | 733000000 | 177000000000 | 0.4112 | 0.2401 | 0.0009 | 0.0003 | 0.0037 | 0.0006 | 0.0107 | 0.0009 | 0.0409 | 0.0027 | 0.0991 | 0.0285 | 0.1647 | 0.0612 | 0.1629 | 0.0558 | 0.2010 | 0.0876 | 0.3160 | 0.7623 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0050 | 0.0000 | 0.0210 | 0.0014 | 0.0522 | 0.0177 | 0.0878 | 0.0343 | 0.0906 | 0.0296 | 0.1372 | 0.0500 | 0.6048 | 0.8670 | 0.0060 | 0.0031 | 0.0105 | 0.0031 | 0.0180 | 0.0251 | 0.0481 | 0.0721 | 0.1008 | 0.1755 | 0.1474 | 0.1850 | 0.1158 | 0.1129 | 0.1549 | 0.1348 | 0.3985 | 0.2884 | 0.0049 | 0.0084 | 0.0182 | 0.0477 | 0.0869 | 0.1170 | 0.0953 | 0.0988 | 0.5228 | 9 | 13 | 17 | 21 | 25 | 32 | 40 | 53 | 80 | 0.0260 | 5.48 | 4.415 | 0.5610 | 2685.3 | 330423 | 59700000 | 14100000000 | 0.5938 | 0.1120 | 0.0235 | 0.0088 | 0.0780 | 0.0186 | 0.1751 | 0.0368 | 0.2151 | 0.0862 | 0.2240 | 0.1372 | 0.1421 | 0.1696 | 0.0882 | 0.1863 | 0.0406 | 0.1875 | 0.0133 | 0.1690 | 0.0060 | 0.0053 | 0.0070 | 0.0086 | 0.0141 | 0.0129 | 0.0319 | 0.0244 | 0.0718 | 0.0561 | 0.1115 | 0.0821 | 0.1027 | 0.0929 | 0.1364 | 0.1305 | 0.5185 | 0.5871 | 0.0033 | 0.0083 | 0.0129 | 0.0119 | 0.0220 | 0.0217 | 0.0407 | 0.0620 | 0.1073 | 0.1168 | 0.1401 | 0.1302 | 0.1052 | 0.1111 | 0.1393 | 0.1292 | 0.4291 | 0.4088 | 0.0032 | 0.0106 | 0.0122 | 0.0448 | 0.0860 | 0.1246 | 0.1159 | 0.1259 | 0.4767 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 470 | 334 | | 17082 | 34713 | 121.5 | 40.86 | 150.26 | 149.90 | 78 | 87 | 96 | 104 | 113 | 124 | 137 | 153 | 176 | 0.0613 | 2127 | 0.917 | 53.45 | 21.26 | 5 | 0.0091 | 155 | 0.0008 | 47.08 | 7.438 | 0.1848 | 16426.1 | 2470000 | 412000000 | 75400000000 | 0.5115 | 0.1584 | 0.0012 | 0.0001 | 0.0040 | 0.0001 | 0.0120 | 0.0016 | 0.0473 | 0.0092 | 0.1219 | 0.0386 | 0.1808 | 0.0802 | 0.1691 | 0.0807 | 0.1727 | 0.1152 | 0.2911 | 0.6742 | 0.0005 | 0.0001 | 0.0019 | 0.0001 | 0.0033 | 0.0009 | 0.0140 | 0.0056 | 0.0416 | 0.0205 | 0.0689 | 0.0420 | 0.0618 | 0.0336 | 0.0900 | 0.0533 | 0.7179 | 0.8439 | 0.0012 | 0.0043 | 0.0043 | 0.0104 | 0.0127 | 0.0293 | 0.0437 | 0.0804 | 0.1009 | 0.1268 | 0.1386 | 0.1608 | 0.1105 | 0.1154 | 0.1410 | 0.1334 | 0.4469 | 0.3392 | 0.0011 | 0.0023 | 0.0098 | 0.0256 | 0.0655 | 0.1021 | 0.0917 | 0.1081 | 0.5939 | 13 | 20 | 40 | 73 | 109 | 146 | 192 | 255 | 354 | 0.0246 | 17.30 | 5.572 | 0.4804 | 45049.4 | 19600000 | 11700000000 | 9560000000000 | 0.5599 | 0.1198 | 0.0163 | 0.0018 | 0.0736 | 0.0061 | 0.1603 | 0.0328 | 0.1540 | 0.0660 | 0.1820 | 0.1370 | 0.1647 | 0.1862 | 0.1066 | 0.1461 | 0.0830 | 0.1520 | 0.0595 | 0.2718 | 0.0002 | 0.0004 | 0.0015 | 0.0006 | 0.0032 | 0.0019 | 0.0118 | 0.0080 | 0.0480 | 0.0350 | 0.0826 | 0.0652 | 0.0678 | 0.0531 | 0.0929 | 0.0754 | 0.6920 | 0.7604 | 0.0006 | 0.0013 | 0.0019 | 0.0026 | 0.0068 | 0.0081 | 0.0218 | 0.0295 | 0.0745 | 0.0894 | 0.1255 | 0.1446 | 0.0963 | 0.1068 | 0.1258 | 0.1351 | 0.5468 | 0.4826 | 0.0005 | 0.0014 | 0.0039 | 0.0169 | 0.0590 | 0.1040 | 0.0801 | 0.1148 | 0.6194 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 558 | 297 | | 5154 | 21541 | 500.5 | 100.92 | 62.27 | 98.68 | 379 | 413 | 441 | 465 | 489 | 516 | 545 | 583 | 643 | 0.0452 | 974 | 1.154 | 82.42 | 31.26 | 1 | 0.0415 | 214 | 0.0008 | 54.34 | 7.369 | 0.1710 | 260702.0 | 141000000 | 79400000000 | 46200000000000 | 0.4202 | 0.2271 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0017 | 0.0002 | 0.0098 | 0.0012 | 0.0500 | 0.0161 | 0.1015 | 0.0368 | 0.0980 | 0.0279 | 0.1322 | 0.0328 | 0.6056 | 0.8850 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0006 | 0.0245 | 0.0117 | 0.0493 | 0.0242 | 0.0433 | 0.0125 | 0.0646 | 0.0189 | 0.8118 | 0.9320 | 0.0012 | 0.0000 | 0.0048 | 0.0048 | 0.0119 | 0.0193 | 0.0523 | 0.1063 | 0.1010 | 0.1401 | 0.1354 | 0.2415 | 0.0926 | 0.0918 | 0.1330 | 0.1594 | 0.4679 | 0.2367 | 0.0004 | 0.0034 | 0.0068 | 0.0256 | 0.0631 | 0.1062 | 0.0981 | 0.1207 | 0.5755 | 7 | 8 | 9 | 11 | 13 | 22 | 54 | 107 | 186 | 0.1524 | 8.90 | 3.882 | 0.6556 | 13615.0 | 4670000 | 2040000000 | 1060000000000 | 0.5472 | 0.1233 | 0.0212 | 0.0048 | 0.0778 | 0.0100 | 0.2184 | 0.0291 | 0.2431 | 0.0917 | 0.2007 | 0.1943 | 0.1344 | 0.2273 | 0.0654 | 0.1586 | 0.0309 | 0.1369 | 0.0080 | 0.1473 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0018 | 0.0020 | 0.0078 | 0.0083 | 0.0383 | 0.0319 | 0.0619 | 0.0584 | 0.0403 | 0.0398 | 0.0605 | 0.0521 | 0.7895 | 0.8065 | 0.0000 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0038 | 0.0112 | 0.0113 | 0.0443 | 0.0457 | 0.0656 | 0.0707 | 0.0474 | 0.0532 | 0.0740 | 0.0811 | 0.7534 | 0.7324 | 0.0003 | 0.0000 | 0.0021 | 0.0080 | 0.0402 | 0.0651 | 0.0435 | 0.0623 | 0.7784 | ||
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 855 | 295 | | 10991 | 23655 | 262.5 | 76.92 | 158.35 | 201.26 | 177 | 198 | 216 | 232 | 250 | 269 | 292 | 321 | 366 | 0.0567 | 1341 | 1.156 | 118.61 | 44.10 | 2 | 0.0278 | 305 | 0.0005 | 81.23 | 7.822 | 0.1418 | 74835.2 | 23200000 | 7750000000 | 2800000000000 | 0.4804 | 0.1627 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0071 | 0.0009 | 0.0294 | 0.0045 | 0.0907 | 0.0256 | 0.1763 | 0.0635 | 0.1516 | 0.0562 | 0.1834 | 0.0790 | 0.3603 | 0.7703 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0004 | 0.0117 | 0.0023 | 0.0349 | 0.0146 | 0.0759 | 0.0366 | 0.0625 | 0.0262 | 0.0909 | 0.0372 | 0.7224 | 0.8828 | 0.0004 | 0.0038 | 0.0059 | 0.0084 | 0.0143 | 0.0188 | 0.0412 | 0.0619 | 0.1017 | 0.1210 | 0.1509 | 0.1642 | 0.1076 | 0.1098 | 0.1366 | 0.1407 | 0.4414 | 0.3715 | 0.0008 | 0.0036 | 0.0096 | 0.0273 | 0.0644 | 0.1087 | 0.0818 | 0.1101 | 0.5937 | 10 | 12 | 15 | 20 | 43 | 109 | 209 | 323 | 476 | 0.0700 | 31.05 | 5.286 | 0.4973 | 65578.9 | 35100000 | 21700000000 | 15000000000000 | 0.5467 | 0.1326 | 0.0587 | 0.0020 | 0.2015 | 0.0205 | 0.3009 | 0.1523 | 0.1628 | 0.1523 | 0.1274 | 0.1764 | 0.0861 | 0.1946 | 0.0327 | 0.1099 | 0.0254 | 0.0900 | 0.0047 | 0.1020 | 0.0002 | 0.0002 | 0.0004 | 0.0001 | 0.0015 | 0.0005 | 0.0054 | 0.0054 | 0.0421 | 0.0359 | 0.0826 | 0.0761 | 0.0556 | 0.0480 | 0.0768 | 0.0648 | 0.7354 | 0.7690 | 0.0001 | 0.0000 | 0.0009 | 0.0009 | 0.0029 | 0.0031 | 0.0107 | 0.0130 | 0.0544 | 0.0570 | 0.1019 | 0.1180 | 0.0672 | 0.0698 | 0.0986 | 0.1004 | 0.6631 | 0.6377 | 0.0001 | 0.0002 | 0.0014 | 0.0079 | 0.0478 | 0.0936 | 0.0584 | 0.0901 | 0.7003 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 430 | | 9439 | 30387 | 187.6 | 49.18 | 85.43 | 137.20 | 127 | 150 | 163 | 176 | 187 | 199 | 211 | 226 | 249 | 0.0448 | 1360 | 0.978 | 133.06 | 44.05 | 3 | 0.0366 | 345 | 0.0011 | 36.27 | 7.174 | 0.1963 | 37625.0 | 7970000 | 1770000000 | 413000000000 | 0.4260 | 0.2189 | 0.0002 | 0.0000 | 0.0009 | 0.0001 | 0.0043 | 0.0007 | 0.0199 | 0.0027 | 0.0634 | 0.0169 | 0.1233 | 0.0399 | 0.1423 | 0.0401 | 0.1734 | 0.0580 | 0.4723 | 0.8415 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0072 | 0.0010 | 0.0225 | 0.0102 | 0.0434 | 0.0235 | 0.0516 | 0.0149 | 0.0628 | 0.0250 | 0.8102 | 0.9254 | 0.0063 | 0.0066 | 0.0083 | 0.0115 | 0.0276 | 0.0508 | 0.0683 | 0.0869 | 0.1017 | 0.1328 | 0.1424 | 0.1410 | 0.1226 | 0.1016 | 0.1346 | 0.1279 | 0.3881 | 0.3410 | 0.0009 | 0.0032 | 0.0071 | 0.0234 | 0.0626 | 0.0939 | 0.0934 | 0.1316 | 0.5841 | 10 | 12 | 14 | 16 | 20 | 29 | 62 | 140 | 267 | 0.1579 | 16.30 | 3.924 | 0.6407 | 26120.0 | 12600000 | 7750000000 | 5660000000000 | 0.5727 | 0.1271 | 0.1171 | 0.0076 | 0.2705 | 0.0420 | 0.2342 | 0.2186 | 0.1164 | 0.1757 | 0.1023 | 0.1567 | 0.0686 | 0.1384 | 0.0444 | 0.0856 | 0.0316 | 0.0752 | 0.0148 | 0.1002 | 0.0003 | 0.0005 | 0.0015 | 0.0008 | 0.0032 | 0.0031 | 0.0147 | 0.0133 | 0.0655 | 0.0528 | 0.0960 | 0.0906 | 0.0648 | 0.0549 | 0.0997 | 0.0876 | 0.6543 | 0.6964 | 0.0001 | 0.0004 | 0.0007 | 0.0004 | 0.0029 | 0.0039 | 0.0241 | 0.0258 | 0.0759 | 0.0823 | 0.1193 | 0.1295 | 0.0787 | 0.0827 | 0.1092 | 0.1138 | 0.5892 | 0.5612 | 0.0004 | 0.0010 | 0.0023 | 0.0194 | 0.0694 | 0.1084 | 0.0725 | 0.1053 | 0.6214 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1168 | 424 | | 6546 | 17083 | 401.6 | 88.26 | 135.51 | 179.85 | 299 | 325 | 346 | 367 | 388 | 411 | 439 | 479 | 531 | 0.0520 | 889 | 1.155 | 97.74 | 36.50 | 1 | 0.0390 | 255 | 0.0006 | 73.03 | 7.599 | 0.1457 | 169066.0 | 74500000 | 34300000000 | 16500000000000 | 0.4391 | 0.2054 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0024 | 0.0003 | 0.0156 | 0.0020 | 0.0721 | 0.0202 | 0.1564 | 0.0399 | 0.1454 | 0.0398 | 0.1652 | 0.0640 | 0.4415 | 0.8338 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0067 | 0.0003 | 0.0328 | 0.0108 | 0.0762 | 0.0234 | 0.0686 | 0.0168 | 0.0916 | 0.0321 | 0.7229 | 0.9166 | 0.0000 | 0.0086 | 0.0056 | 0.0115 | 0.0104 | 0.0576 | 0.0569 | 0.1124 | 0.1018 | 0.1960 | 0.1604 | 0.2219 | 0.1099 | 0.1441 | 0.1299 | 0.1210 | 0.4250 | 0.1268 | 0.0014 | 0.0056 | 0.0112 | 0.0352 | 0.0715 | 0.1141 | 0.0855 | 0.1018 | 0.5738 | 6 | 9 | 12 | 24 | 53 | 96 | 159 | 245 | 398 | 0.0690 | 25.10 | 5.074 | 0.4896 | 50707.9 | 26800000 | 17300000000 | 12900000000000 | 0.5220 | 0.1303 | 0.0750 | 0.0031 | 0.1918 | 0.0288 | 0.2725 | 0.1436 | 0.1472 | 0.1470 | 0.1168 | 0.1845 | 0.0842 | 0.1772 | 0.0566 | 0.1189 | 0.0340 | 0.0954 | 0.0219 | 0.1016 | 0.0002 | 0.0003 | 0.0006 | 0.0001 | 0.0031 | 0.0029 | 0.0159 | 0.0113 | 0.0618 | 0.0534 | 0.1096 | 0.0985 | 0.0694 | 0.0658 | 0.1005 | 0.0962 | 0.6390 | 0.6716 | 0.0004 | 0.0009 | 0.0024 | 0.0025 | 0.0050 | 0.0096 | 0.0203 | 0.0215 | 0.0764 | 0.0900 | 0.1299 | 0.1292 | 0.0772 | 0.0830 | 0.1085 | 0.1212 | 0.5799 | 0.5421 | 0.0004 | 0.0014 | 0.0042 | 0.0152 | 0.0716 | 0.1197 | 0.0695 | 0.1083 | 0.6097 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 343 | 118 | | 16901 | 26398 | 141.3 | 44.30 | 218.23 | 252.21 | 94 | 105 | 114 | 123 | 132 | 143 | 157 | 175 | 204 | 0.0815 | 2151 | 0.681 | 101.95 | 26.17 | 6 | 0.0180 | 304 | 0.0015 | 29.37 | 6.914 | 0.2233 | 21941.5 | 3740000 | 696000000 | 140000000000 | 0.5305 | 0.1501 | 0.0011 | 0.0003 | 0.0048 | 0.0008 | 0.0158 | 0.0020 | 0.0410 | 0.0075 | 0.1072 | 0.0328 | 0.1650 | 0.0728 | 0.1666 | 0.0720 | 0.1890 | 0.1025 | 0.3095 | 0.7093 | 0.0006 | 0.0002 | 0.0026 | 0.0004 | 0.0058 | 0.0011 | 0.0146 | 0.0036 | 0.0408 | 0.0175 | 0.0693 | 0.0366 | 0.0679 | 0.0300 | 0.0954 | 0.0486 | 0.7030 | 0.8620 | 0.0021 | 0.0030 | 0.0070 | 0.0090 | 0.0120 | 0.0200 | 0.0527 | 0.0656 | 0.1020 | 0.1512 | 0.1411 | 0.1773 | 0.1049 | 0.1097 | 0.1331 | 0.1607 | 0.4451 | 0.3035 | 0.0015 | 0.0049 | 0.0131 | 0.0289 | 0.0754 | 0.1125 | 0.0940 | 0.1202 | 0.5495 | 20 | 29 | 48 | 79 | 120 | 175 | 259 | 375 | 570 | 0.0118 | 66.19 | 6.470 | 0.3644 | 111232.0 | 85900000 | 88000000000 | 113000000000000 | 0.5942 | 0.0903 | 0.0589 | 0.0022 | 0.1898 | 0.0187 | 0.2385 | 0.1095 | 0.1625 | 0.1457 | 0.1298 | 0.1893 | 0.1051 | 0.1818 | 0.0549 | 0.1192 | 0.0407 | 0.1100 | 0.0196 | 0.1236 | 0.0006 | 0.0005 | 0.0022 | 0.0016 | 0.0043 | 0.0051 | 0.0185 | 0.0152 | 0.0708 | 0.0630 | 0.1147 | 0.0979 | 0.0818 | 0.0754 | 0.1208 | 0.1064 | 0.5863 | 0.6349 | 0.0003 | 0.0018 | 0.0031 | 0.0043 | 0.0077 | 0.0110 | 0.0323 | 0.0372 | 0.0907 | 0.0969 | 0.1399 | 0.1479 | 0.1021 | 0.1013 | 0.1285 | 0.1341 | 0.4956 | 0.4656 | 0.0010 | 0.0025 | 0.0059 | 0.0245 | 0.0763 | 0.1324 | 0.0895 | 0.1228 | 0.5449 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 707 | | 13530 | 19255 | 474.1 | 126.99 | 20.39 | 53.21 | 304 | 394 | 439 | 470 | 494 | 519 | 545 | 573 | 609 | 0.0718 | 1383 | 0.981 | 73.41 | 26.31 | 10 | 0.0152 | 205 | 0.0008 | 44.28 | 7.548 | 0.2080 | 240855.0 | 127000000 | 69400000000 | 38700000000000 | 0.5339 | 0.1308 | 0.0006 | 0.0000 | 0.0010 | 0.0001 | 0.0043 | 0.0006 | 0.0142 | 0.0018 | 0.0585 | 0.0189 | 0.1017 | 0.0371 | 0.0863 | 0.0264 | 0.1091 | 0.0426 | 0.6244 | 0.8725 | 0.0001 | 0.0000 | 0.0002 | 0.0001 | 0.0001 | 0.0000 | 0.0015 | 0.0008 | 0.0170 | 0.0145 | 0.0361 | 0.0292 | 0.0214 | 0.0147 | 0.0347 | 0.0225 | 0.8889 | 0.9183 | 0.0031 | 0.0204 | 0.0058 | 0.0051 | 0.0170 | 0.0636 | 0.0458 | 0.1018 | 0.1021 | 0.1552 | 0.1378 | 0.1578 | 0.1116 | 0.1603 | 0.1412 | 0.1425 | 0.4357 | 0.1934 | 0.0001 | 0.0006 | 0.0021 | 0.0108 | 0.0390 | 0.0782 | 0.0620 | 0.0866 | 0.7204 | 6 | 7 | 8 | 9 | 10 | 11 | 13 | 16 | 31 | 0.4315 | 1.39 | 1.784 | 0.8626 | 3247.0 | 1790000 | 1370000000 | 1200000000000 | 0.6652 | 0.0672 | 0.0808 | 0.0848 | 0.0820 | 0.0869 | 0.1165 | 0.0731 | 0.1440 | 0.0714 | 0.1647 | 0.0831 | 0.1540 | 0.1070 | 0.1277 | 0.1051 | 0.0977 | 0.1288 | 0.0326 | 0.2598 | 0.0277 | 0.0558 | 0.0224 | 0.0571 | 0.0301 | 0.0465 | 0.0388 | 0.0399 | 0.0653 | 0.0505 | 0.0774 | 0.0737 | 0.0629 | 0.0667 | 0.0863 | 0.0911 | 0.5891 | 0.5187 | 0.0078 | 0.0032 | 0.0078 | 0.0050 | 0.0078 | 0.0140 | 0.0168 | 0.0235 | 0.0588 | 0.0587 | 0.0748 | 0.0898 | 0.0643 | 0.0700 | 0.1019 | 0.1020 | 0.6599 | 0.6339 | 0.0183 | 0.0157 | 0.0223 | 0.0265 | 0.0465 | 0.0750 | 0.0550 | 0.0917 | 0.6490 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 116 | 222 | | 4981 | 10103 | 405.1 | 89.96 | 157.47 | 168.79 | 303 | 330 | 351 | 372 | 393 | 414 | 437 | 472 | 529 | 0.0726 | 733 | 0.947 | 146.69 | 44.27 | 1 | 0.0765 | 381 | 0.0010 | 46.38 | 7.194 | 0.1694 | 172181.0 | 76900000 | 36100000000 | 17800000000000 | 0.4170 | 0.2320 | 0.0009 | 0.0000 | 0.0006 | 0.0002 | 0.0061 | 0.0002 | 0.0134 | 0.0030 | 0.0510 | 0.0201 | 0.1197 | 0.0402 | 0.1212 | 0.0369 | 0.1555 | 0.0520 | 0.5316 | 0.8474 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0051 | 0.0006 | 0.0261 | 0.0128 | 0.0622 | 0.0261 | 0.0566 | 0.0170 | 0.0832 | 0.0251 | 0.7642 | 0.9184 | 0.0000 | 0.0065 | 0.0095 | 0.0032 | 0.0202 | 0.0356 | 0.0606 | 0.0874 | 0.1021 | 0.1392 | 0.1164 | 0.1359 | 0.1152 | 0.1456 | 0.1318 | 0.1230 | 0.4442 | 0.3236 | 0.0000 | 0.0045 | 0.0050 | 0.0389 | 0.0811 | 0.1241 | 0.0933 | 0.1295 | 0.5236 | 12 | 18 | 27 | 51 | 92 | 149 | 210 | 289 | 400 | 0.0190 | 31.43 | 5.829 | 0.4202 | 53285.1 | 24200000 | 13200000000 | 8210000000000 | 0.4079 | 0.2092 | 0.0230 | 0.0010 | 0.1168 | 0.0114 | 0.2061 | 0.0547 | 0.1914 | 0.1099 | 0.1582 | 0.1932 | 0.1509 | 0.2018 | 0.0846 | 0.1366 | 0.0414 | 0.1376 | 0.0276 | 0.1537 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0011 | 0.0012 | 0.0119 | 0.0086 | 0.0452 | 0.0426 | 0.0796 | 0.0616 | 0.0598 | 0.0476 | 0.0830 | 0.0710 | 0.7189 | 0.7671 | 0.0003 | 0.0007 | 0.0009 | 0.0031 | 0.0060 | 0.0090 | 0.0199 | 0.0193 | 0.0673 | 0.0835 | 0.1185 | 0.1308 | 0.0798 | 0.0860 | 0.1146 | 0.1267 | 0.5929 | 0.5409 | 0.0000 | 0.0010 | 0.0049 | 0.0194 | 0.0537 | 0.0980 | 0.0668 | 0.1011 | 0.6551 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 331 | 718 | | 6517 | 14109 | 121.3 | 38.02 | 212.08 | 139.30 | 76 | 89 | 98 | 106 | 116 | 126 | 139 | 154 | 173 | 0.0670 | 946 | 0.522 | 141.32 | 34.66 | 1 | 0.0758 | 494 | 0.0017 | 23.72 | 6.654 | 0.2362 | 16163.3 | 2350000 | 371000000 | 63300000000 | 0.4672 | 0.1926 | 0.0013 | 0.0002 | 0.0033 | 0.0000 | 0.0140 | 0.0028 | 0.0447 | 0.0100 | 0.1142 | 0.0351 | 0.1883 | 0.0820 | 0.1596 | 0.0767 | 0.1756 | 0.1199 | 0.2990 | 0.6732 | 0.0004 | 0.0002 | 0.0017 | 0.0000 | 0.0041 | 0.0012 | 0.0137 | 0.0047 | 0.0345 | 0.0203 | 0.0687 | 0.0391 | 0.0668 | 0.0281 | 0.0852 | 0.0555 | 0.7248 | 0.8511 | 0.0006 | 0.0027 | 0.0019 | 0.0190 | 0.0131 | 0.0244 | 0.0473 | 0.0799 | 0.1021 | 0.1721 | 0.1594 | 0.2033 | 0.1152 | 0.1179 | 0.1519 | 0.1518 | 0.4085 | 0.2290 | 0.0014 | 0.0024 | 0.0106 | 0.0294 | 0.0608 | 0.1086 | 0.0820 | 0.1134 | 0.5914 | 42 | 83 | 121 | 156 | 193 | 231 | 273 | 329 | 409 | 0.0025 | 30.32 | 6.672 | 0.2808 | 64379.2 | 23700000 | 9980000000 | 4630000000000 | 0.5768 | 0.1249 | 0.0132 | 0.0007 | 0.0829 | 0.0038 | 0.2244 | 0.0304 | 0.2064 | 0.0794 | 0.1855 | 0.1514 | 0.1565 | 0.2137 | 0.0868 | 0.1808 | 0.0344 | 0.1635 | 0.0100 | 0.1763 | 0.0005 | 0.0000 | 0.0010 | 0.0005 | 0.0062 | 0.0022 | 0.0221 | 0.0124 | 0.0612 | 0.0460 | 0.1242 | 0.0904 | 0.0972 | 0.0798 | 0.1246 | 0.1106 | 0.5630 | 0.6581 | 0.0029 | 0.0020 | 0.0062 | 0.0061 | 0.0179 | 0.0276 | 0.0458 | 0.0711 | 0.1142 | 0.1294 | 0.1552 | 0.1673 | 0.1257 | 0.1207 | 0.1490 | 0.1595 | 0.3830 | 0.3164 | 0.0008 | 0.0041 | 0.0099 | 0.0341 | 0.0887 | 0.1328 | 0.1162 | 0.1460 | 0.4674 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 158 | 814 | | 6792 | 9233 | 438.4 | 87.62 | 129.25 | 126.89 | 328 | 360 | 387 | 410 | 432 | 453 | 478 | 510 | 563 | 0.1039 | 959 | 1.120 | 105.12 | 29.02 | 1 | 0.0346 | 235 | 0.0009 | 45.63 | 7.284 | 0.1766 | 199847.0 | 94600000 | 46500000000 | 23600000000000 | 0.4114 | 0.2340 | 0.0002 | 0.0000 | 0.0009 | 0.0002 | 0.0029 | 0.0003 | 0.0152 | 0.0014 | 0.0530 | 0.0166 | 0.1082 | 0.0302 | 0.1148 | 0.0269 | 0.1594 | 0.0440 | 0.5454 | 0.8804 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0012 | 0.0000 | 0.0064 | 0.0000 | 0.0246 | 0.0109 | 0.0515 | 0.0199 | 0.0494 | 0.0108 | 0.0729 | 0.0223 | 0.7933 | 0.9361 | 0.0091 | 0.0087 | 0.0172 | 0.0435 | 0.0199 | 0.0913 | 0.0661 | 0.1174 | 0.1024 | 0.2261 | 0.1386 | 0.1174 | 0.1232 | 0.1739 | 0.1132 | 0.0870 | 0.4103 | 0.1348 | 0.0006 | 0.0025 | 0.0094 | 0.0253 | 0.0738 | 0.1200 | 0.1088 | 0.1385 | 0.5211 | 15 | 21 | 36 | 60 | 91 | 123 | 163 | 221 | 310 | 0.0144 | 22.41 | 5.893 | 0.4120 | 32805.8 | 11500000 | 4920000000 | 2420000000000 | 0.5918 | 0.1102 | 0.0326 | 0.0008 | 0.0932 | 0.0126 | 0.1546 | 0.0502 | 0.1430 | 0.0942 | 0.1492 | 0.1468 | 0.1430 | 0.1554 | 0.1072 | 0.1181 | 0.1049 | 0.1370 | 0.0723 | 0.2849 | 0.0002 | 0.0000 | 0.0012 | 0.0004 | 0.0062 | 0.0042 | 0.0208 | 0.0156 | 0.0649 | 0.0540 | 0.0900 | 0.0828 | 0.0815 | 0.0608 | 0.1083 | 0.0905 | 0.6269 | 0.6917 | 0.0017 | 0.0008 | 0.0031 | 0.0078 | 0.0133 | 0.0090 | 0.0269 | 0.0377 | 0.0941 | 0.1099 | 0.1339 | 0.1333 | 0.0896 | 0.1005 | 0.1210 | 0.1255 | 0.5164 | 0.4754 | 0.0009 | 0.0028 | 0.0079 | 0.0247 | 0.0791 | 0.1123 | 0.0879 | 0.1140 | 0.5705 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 713 | 522 | | 16894 | 27359 | 277.6 | 52.05 | 216.35 | 215.57 | 208 | 237 | 256 | 269 | 281 | 294 | 306 | 320 | 341 | 0.0538 | 1471 | 1.091 | 103.16 | 31.06 | 2 | 0.0146 | 247 | 0.0019 | 13.94 | 6.613 | 0.2949 | 79797.3 | 23600000 | 7150000000 | 2220000000000 | 0.4393 | 0.2062 | 0.0005 | 0.0001 | 0.0011 | 0.0000 | 0.0033 | 0.0002 | 0.0092 | 0.0012 | 0.0381 | 0.0103 | 0.0669 | 0.0200 | 0.0670 | 0.0172 | 0.0957 | 0.0278 | 0.7182 | 0.9233 | 0.0001 | 0.0001 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0036 | 0.0009 | 0.0175 | 0.0093 | 0.0294 | 0.0173 | 0.0273 | 0.0120 | 0.0360 | 0.0204 | 0.8849 | 0.9400 | 0.0059 | 0.0000 | 0.0174 | 0.0000 | 0.0329 | 0.0000 | 0.0567 | 0.0000 | 0.1025 | 0.0000 | 0.1459 | 0.0000 | 0.1189 | 0.0000 | 0.1432 | 0.0000 | 0.3765 | 0.0000 | 0.0017 | 0.0028 | 0.0050 | 0.0176 | 0.0419 | 0.0771 | 0.0726 | 0.0997 | 0.6818 | 21 | 32 | 52 | 93 | 142 | 205 | 283 | 380 | 530 | 0.0112 | 32.03 | 6.315 | 0.3897 | 93278.7 | 53900000 | 36900000000 | 28400000000000 | 0.5194 | 0.1468 | 0.0368 | 0.0022 | 0.1715 | 0.0112 | 0.2748 | 0.0782 | 0.1614 | 0.1448 | 0.1334 | 0.1933 | 0.0945 | 0.1853 | 0.0577 | 0.1275 | 0.0408 | 0.1189 | 0.0291 | 0.1384 | 0.0004 | 0.0005 | 0.0011 | 0.0010 | 0.0036 | 0.0028 | 0.0148 | 0.0107 | 0.0581 | 0.0512 | 0.1064 | 0.0873 | 0.0753 | 0.0672 | 0.1096 | 0.0986 | 0.6307 | 0.6805 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0066 | 0.0087 | 0.0278 | 0.0330 | 0.0781 | 0.0932 | 0.1289 | 0.1454 | 0.1017 | 0.1011 | 0.1260 | 0.1267 | 0.5291 | 0.4877 | 0.0007 | 0.0016 | 0.0048 | 0.0183 | 0.0725 | 0.1147 | 0.0880 | 0.1182 | 0.5812 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 434 | 702 | | 366 | 1008 | 101.8 | 15.33 | 117.32 | 181.93 | 80 | 86 | 92 | 98 | 103 | 108 | 111 | 115 | 124 | 0.2123 | 214 | 1.232 | 111.40 | 47.13 | 1 | 0.7978 | 292 | 0.0164 | 2.19 | 4.307 | 0.5322 | 10587.6 | 1130000 | 122000000 | 13400000000 | 0.3074 | 0.3364 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0000 | 0.0000 | 0.0211 | 0.0055 | 0.0526 | 0.0437 | 0.1719 | 0.1202 | 0.0842 | 0.0328 | 0.0982 | 0.0437 | 0.5684 | 0.7541 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0123 | 0.0055 | 0.0401 | 0.0437 | 0.1204 | 0.1202 | 0.0432 | 0.0328 | 0.0401 | 0.0437 | 0.7438 | 0.7541 | 0.0000 | 0.0000 | 0.0256 | 0.0000 | 0.0256 | 0.0000 | 0.1026 | 0.0000 | 0.1026 | 0.0000 | 0.2051 | 0.0000 | 0.1026 | 0.0000 | 0.2308 | 0.0000 | 0.2051 | 0.0000 | 0.0000 | 0.0000 | 0.0158 | 0.0263 | 0.0526 | 0.1316 | 0.0842 | 0.0947 | 0.5947 | 11 | 13 | 15 | 21 | 33 | 58 | 109 | 190 | 334 | 0.1012 | 55.96 | 4.139 | 0.5623 | 46830.7 | 29000000 | 21700000000 | 18100000000000 | 0.4240 | 0.1879 | 0.1642 | 0.0070 | 0.2537 | 0.0986 | 0.1642 | 0.1690 | 0.1493 | 0.1408 | 0.1194 | 0.1408 | 0.0896 | 0.1620 | 0.0448 | 0.1056 | 0.0149 | 0.0986 | 0.0000 | 0.0775 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0061 | 0.0027 | 0.0457 | 0.0348 | 0.0793 | 0.0668 | 0.1250 | 0.1364 | 0.0854 | 0.0668 | 0.1494 | 0.1337 | 0.5091 | 0.5588 | 0.0000 | 0.0043 | 0.0038 | 0.0086 | 0.0268 | 0.0172 | 0.0345 | 0.0302 | 0.1188 | 0.1207 | 0.1341 | 0.1466 | 0.0996 | 0.1034 | 0.1533 | 0.1767 | 0.4291 | 0.3922 | 0.0000 | 0.0035 | 0.0177 | 0.0389 | 0.0989 | 0.1272 | 0.1095 | 0.1484 | 0.4558 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1146 | 391 | | 12697 | 38415 | 310.0 | 92.49 | 153.57 | 202.77 | 205 | 234 | 255 | 274 | 295 | 319 | 346 | 384 | 440 | 0.0394 | 1513 | 0.946 | 124.09 | 49.52 | 3 | 0.0296 | 376 | 0.0009 | 41.44 | 7.326 | 0.1956 | 104638.0 | 38300000 | 15100000000 | 6390000000000 | 0.4357 | 0.2157 | 0.0002 | 0.0000 | 0.0023 | 0.0003 | 0.0069 | 0.0013 | 0.0281 | 0.0029 | 0.1035 | 0.0300 | 0.1722 | 0.0701 | 0.1505 | 0.0612 | 0.1633 | 0.0843 | 0.3731 | 0.7500 | 0.0001 | 0.0000 | 0.0015 | 0.0003 | 0.0028 | 0.0007 | 0.0089 | 0.0013 | 0.0404 | 0.0164 | 0.0715 | 0.0341 | 0.0623 | 0.0255 | 0.0826 | 0.0378 | 0.7299 | 0.8841 | 0.0017 | 0.0022 | 0.0045 | 0.0058 | 0.0083 | 0.0145 | 0.0403 | 0.0608 | 0.1026 | 0.1398 | 0.1520 | 0.2013 | 0.0911 | 0.1043 | 0.1273 | 0.1521 | 0.4720 | 0.3193 | 0.0016 | 0.0023 | 0.0054 | 0.0291 | 0.0756 | 0.1167 | 0.0885 | 0.1148 | 0.5659 | 7 | 9 | 11 | 17 | 46 | 106 | 192 | 307 | 462 | 0.0898 | 34.20 | 5.290 | 0.4957 | 64699.3 | 36300000 | 24200000000 | 18400000000000 | 0.3650 | 0.2639 | 0.0547 | 0.0028 | 0.2149 | 0.0156 | 0.2794 | 0.1388 | 0.1508 | 0.1713 | 0.1178 | 0.1966 | 0.0866 | 0.1720 | 0.0420 | 0.1084 | 0.0341 | 0.0926 | 0.0196 | 0.1020 | 0.0001 | 0.0002 | 0.0001 | 0.0004 | 0.0008 | 0.0006 | 0.0081 | 0.0072 | 0.0485 | 0.0397 | 0.0847 | 0.0723 | 0.0563 | 0.0480 | 0.0892 | 0.0718 | 0.7122 | 0.7599 | 0.0000 | 0.0002 | 0.0003 | 0.0007 | 0.0015 | 0.0026 | 0.0125 | 0.0167 | 0.0667 | 0.0735 | 0.1084 | 0.1144 | 0.0679 | 0.0763 | 0.1080 | 0.1128 | 0.6346 | 0.6028 | 0.0000 | 0.0003 | 0.0014 | 0.0088 | 0.0599 | 0.0938 | 0.0662 | 0.0996 | 0.6699 |