High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
BT-20 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 1211 757 image if available 6987 17413 330.1 42.49 131.75 174.14 277 295 309 320 331 341 352 366 384 0.0637 1110 0.875 72.84 16.16 1 0.0238 166 0.0022 16.55 6.447 0.2611 110777.0
37800000
13100000000
4580000000000
0.4400 0.2087 0.0000 0.0000 0.0005 0.0000 0.0010 0.0000 0.0062 0.0000 0.0213 0.0109 0.0321 0.0178 0.0485 0.0100 0.0745 0.0186 0.8160 0.9427 0.0000 0.0000 0.0002 0.0000 0.0003 0.0000 0.0027 0.0000 0.0128 0.0109 0.0169 0.0178 0.0198 0.0095 0.0305 0.0166 0.9167 0.9453 0.0122 0.0000 0.0389 1.0000 0.0681 0.0000 0.1387 0.0000 0.1363 0.0000 0.1533 0.0000 0.1314 0.0000 0.1265 0.0000 0.1946 0.0000 0.0017 0.0047 0.0111 0.0255 0.0505 0.0813 0.0921 0.1160 0.6171 11 14 16 20 45 85 148 242 391 0.0761 18.56 4.883 0.5466 47679.7
24000000
14300000000
9510000000000
0.5710 0.1004 0.0354 0.0022 0.1286 0.0170 0.1973 0.0815 0.1517 0.1130 0.1402 0.1735 0.1156 0.1590 0.0860 0.1101 0.0744 0.1093 0.0708 0.2342 0.0002 0.0003 0.0005 0.0013 0.0017 0.0015 0.0103 0.0083 0.0444 0.0392 0.0713 0.0616 0.0547 0.0447 0.0799 0.0686 0.7370 0.7746 0.0002 0.0007 0.0022 0.0016 0.0044 0.0034 0.0156 0.0158 0.0577 0.0657 0.0944 0.1062 0.0716 0.0725 0.0954 0.1069 0.6586 0.6274 0.0004 0.0009 0.0034 0.0130 0.0497 0.0852 0.0639 0.0887 0.6949
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 655 519 image if available 12431 24620 390.0 70.08 73.02 145.52 287 322 350 376 398 418 437 454 476 0.0531 1307 0.717 116.71 35.11 3 0.0323 401 0.0014 13.24 6.814 0.3028 157023.0
65000000
27500000000
11900000000000
0.4378 0.1981 0.0007 0.0000 0.0029 0.0000 0.0055 0.0000 0.0115 0.0009 0.0276 0.0098 0.0447 0.0175 0.0492 0.0111 0.0732 0.0171 0.7847 0.9436 0.0001 0.0000 0.0009 0.0000 0.0019 0.0000 0.0037 0.0009 0.0122 0.0098 0.0195 0.0175 0.0178 0.0105 0.0271 0.0152 0.9168 0.9461 0.0102 1.0000 0.0215 0.0000 0.0269 0.0000 0.0449 0.0000 0.0682 0.0000 0.0922 0.0000 0.0999 0.0000 0.1191 0.0000 0.5171 0.0000 0.0007 0.0036 0.0042 0.0104 0.0227 0.0348 0.0407 0.0547 0.8282 8 10 11 13 15 20 33 82 218 0.1379 2.58 2.741 0.6004 26508.4
16200000
12600000000
11400000000000
0.6289 0.0769 0.0413 0.0027 0.1013 0.0182 0.1888 0.0633 0.1750 0.0919 0.1721 0.1461 0.1327 0.1875 0.1013 0.1379 0.0560 0.1347 0.0315 0.2176 0.0002 0.0005 0.0007 0.0006 0.0016 0.0015 0.0123 0.0101 0.0446 0.0428 0.0768 0.0683 0.0519 0.0466 0.0718 0.0703 0.7402 0.7592 0.0004 0.0009 0.0008 0.0018 0.0023 0.0018 0.0159 0.0140 0.0529 0.0605 0.0898 0.0918 0.0567 0.0628 0.0814 0.0868 0.6997 0.6794 0.0004 0.0000 0.0015 0.0114 0.0529 0.0806 0.0550 0.0825 0.7157
MDA-MB-231 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 900 171 image if available 3930 11298 497.7 103.96 94.40 173.19 316 409 476 500 521 540 560 583 613 0.0641 724 0.847 112.54 33.02 4 0.0832 327 0.0011 32.58 7.096 0.2211 258499.0
139000000
76000000000
42400000000000
0.3874 0.2511 0.0008 0.0003 0.0015 0.0000 0.0057 0.0000 0.0069 0.0008 0.0413 0.0186 0.0462 0.0251 0.0569 0.0178 0.0810 0.0276 0.7597 0.9099 0.0000 0.0003 0.0000 0.0000 0.0000 0.0000 0.0003 0.0008 0.0197 0.0186 0.0188 0.0251 0.0172 0.0178 0.0260 0.0276 0.9179 0.9099 0.0052 0.0000 0.0140 0.0000 0.0315 0.0000 0.0542 0.0000 0.0717 0.0000 0.0944 0.0000 0.1119 0.0000 0.1556 0.0000 0.4615 0.0000 0.0012 0.0042 0.0037 0.0108 0.0279 0.0396 0.0500 0.0629 0.7997 6 7 9 10 14 24 52 125 339 0.1266 21.37 4.235 0.6154 38902.8
22700000
15400000000
11500000000000
0.5106 0.1373 0.0416 0.0018 0.1323 0.0210 0.2420 0.0602 0.1739 0.1267 0.1815 0.2124 0.1361 0.2042 0.0586 0.1258 0.0265 0.1167 0.0076 0.1313 0.0000 0.0003 0.0003 0.0009 0.0031 0.0015 0.0097 0.0106 0.0497 0.0439 0.0660 0.0569 0.0453 0.0375 0.0729 0.0623 0.7530 0.7860 0.0000 0.0000 0.0008 0.0000 0.0013 0.0018 0.0139 0.0172 0.0499 0.0548 0.0820 0.0743 0.0465 0.0535 0.0714 0.0729 0.7342 0.7254 0.0008 0.0000 0.0015 0.0131 0.0528 0.0670 0.0466 0.0751 0.7432
MDA-MB-231 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 421 124 image if available 5496 10543 841.5 127.28 116.18 190.68 650 752 803 837 864 891 918 946 983 0.0719 758 0.901 57.38 16.12 1 0.0260 143 0.0008 45.33 7.373 0.1837 724381.0
635000000
565000000000
510000000000000
0.4046 0.2403 0.0000 0.0000 0.0002 0.0002 0.0004 0.0000 0.0037 0.0006 0.0217 0.0126 0.0354 0.0196 0.0394 0.0116 0.0630 0.0199 0.8361 0.9356 0.0000 0.0000 0.0000 0.0002 0.0000 0.0000 0.0019 0.0006 0.0126 0.0126 0.0229 0.0196 0.0169 0.0116 0.0272 0.0199 0.9185 0.9356 0.0145 0.0000 0.0364 0.0000 0.0545 0.0000 0.1200 0.0000 0.1200 0.0000 0.1418 0.0000 0.1455 0.0000 0.1091 0.0000 0.2582 0.0000 0.0016 0.0038 0.0047 0.0144 0.0357 0.0510 0.0620 0.0780 0.7489 11 14 18 24 31 47 83 165 375 0.1122 20.14 4.053 0.6479 49852.9
32900000
26200000000
23500000000000
0.4577 0.2035 0.0423 0.0022 0.1482 0.0186 0.2052 0.1010 0.1580 0.1256 0.1612 0.1330 0.1075 0.1627 0.0749 0.1085 0.0619 0.1226 0.0407 0.2259 0.0007 0.0006 0.0007 0.0012 0.0071 0.0066 0.0172 0.0124 0.0487 0.0469 0.0774 0.0650 0.0551 0.0478 0.0804 0.0728 0.7127 0.7468 0.0000 0.0005 0.0004 0.0014 0.0030 0.0038 0.0179 0.0141 0.0640 0.0756 0.0989 0.1136 0.0648 0.0700 0.0942 0.1103 0.6567 0.6108 0.0000 0.0027 0.0027 0.0170 0.0572 0.0877 0.0634 0.0912 0.6781
MDA-MB-231 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 945 791 image if available 7136 8653 396.4 68.86 331.09 487.17 292 338 365 386 406 423 439 454 478 0.0953 825 1.046 109.66 38.48 6 0.0419 299 0.0024 9.08 6.362 0.3660 161888.0
67800000
29000000000
12700000000000
0.4181 0.2153 0.0006 0.0000 0.0015 0.0000 0.0038 0.0000 0.0079 0.0011 0.0218 0.0106 0.0533 0.0271 0.0385 0.0132 0.0585 0.0186 0.8142 0.9294 0.0000 0.0000 0.0002 0.0000 0.0005 0.0000 0.0025 0.0011 0.0113 0.0105 0.0289 0.0260 0.0141 0.0119 0.0204 0.0173 0.9222 0.9333 0.0066 0.0000 0.0066 0.0000 0.0263 0.0000 0.0447 0.0000 0.1092 0.0000 0.1184 0.0000 0.1158 0.0000 0.1382 0.0000 0.4342 0.0000 0.0005 0.0015 0.0051 0.0101 0.0281 0.0398 0.0367 0.0529 0.8252 10 12 15 26 85 211 381 631 998 0.1055 26.80 5.014 0.5502 346927.0
541000000
1110000000000
2.77E+15
0.4761 0.1685 0.0161 0.0031 0.0966 0.0086 0.1804 0.0350 0.1739 0.0871 0.1643 0.1540 0.1433 0.1882 0.0934 0.1407 0.0805 0.1198 0.0515 0.2636 0.0003 0.0008 0.0006 0.0014 0.0025 0.0017 0.0063 0.0068 0.0348 0.0256 0.0659 0.0501 0.0446 0.0400 0.0681 0.0535 0.7768 0.8202 0.0000 0.0004 0.0004 0.0018 0.0039 0.0049 0.0102 0.0123 0.0481 0.0511 0.0777 0.0886 0.0560 0.0675 0.0765 0.0825 0.7272 0.6909 0.0000 0.0004 0.0036 0.0093 0.0411 0.0750 0.0496 0.0650 0.7562
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 407 716 image if available 7114 12770 534.1 94.65 61.96 146.06 380 451 508 534 555 577 594 611 633 0.0662 846 0.850 97.59 26.25 2 0.0417 297 0.0011 32.30 7.208 0.2276 294243.0
166000000
95600000000
55900000000000
0.4540 0.2027 0.0002 0.0001 0.0009 0.0006 0.0015 0.0003 0.0052 0.0017 0.0232 0.0121 0.0462 0.0176 0.0420 0.0150 0.0641 0.0232 0.8167 0.9294 0.0002 0.0001 0.0003 0.0006 0.0002 0.0003 0.0007 0.0017 0.0128 0.0121 0.0245 0.0176 0.0130 0.0150 0.0239 0.0232 0.9245 0.9294 0.0121 0.0000 0.0208 0.0000 0.0363 0.0000 0.0813 0.0000 0.1142 0.0000 0.1280 0.0000 0.1090 0.0000 0.1228 0.0000 0.3754 0.0000 0.0005 0.0014 0.0054 0.0119 0.0261 0.0428 0.0447 0.0612 0.8061 9 10 11 12 13 15 17 33 165 0.1905 3.26 2.362 0.6175 25171.9
16600000
13100000000
11600000000000
0.6507 0.0699 0.0193 0.0057 0.1322 0.0086 0.2204 0.0743 0.1736 0.1329 0.1267 0.2157 0.0909 0.1571 0.0716 0.0929 0.0661 0.1114 0.0992 0.2014 0.0000 0.0008 0.0009 0.0008 0.0031 0.0028 0.0098 0.0102 0.0459 0.0468 0.0570 0.0533 0.0459 0.0403 0.0731 0.0744 0.7643 0.7706 0.0011 0.0006 0.0021 0.0017 0.0069 0.0040 0.0133 0.0108 0.0436 0.0483 0.0760 0.0802 0.0452 0.0495 0.0803 0.0870 0.7315 0.7180 0.0005 0.0019 0.0048 0.0150 0.0446 0.0650 0.0509 0.0805 0.7368
SK-BR-3 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 532 476 image if available 5219 14862 435.3 124.40 337.57 481.74 232 330 406 440 463 485 504 529 568 0.0615 914 1.000 128.22 48.33 2 0.0674 352 0.0008 45.97 7.490 0.1610 204925.0
101000000
51900000000
27400000000000
0.3800 0.2460 0.0003 0.0000 0.0010 0.0000 0.0028 0.0002 0.0186 0.0019 0.0502 0.0190 0.0908 0.0389 0.0881 0.0283 0.1132 0.0482 0.6350 0.8635 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0020 0.0009 0.0137 0.0123 0.0238 0.0237 0.0137 0.0121 0.0218 0.0185 0.9249 0.9326 0.0043 0.0084 0.0077 0.0422 0.0163 0.0253 0.0463 0.0633 0.0891 0.1266 0.1380 0.2194 0.1157 0.1181 0.1302 0.1646 0.4524 0.2321 0.0000 0.0000 0.0015 0.0080 0.0250 0.0367 0.0598 0.0712 0.7979 11 14 20 38 87 185 377 650 1059 0.0509 117.91 5.882 0.4621 346014.0
476000000
763000000000
1.34E+15
0.4474 0.1983 0.0233 0.0011 0.1329 0.0091 0.3034 0.0582 0.1982 0.0988 0.1639 0.2045 0.0941 0.2654 0.0532 0.1442 0.0199 0.1116 0.0111 0.1073 0.0000 0.0003 0.0002 0.0009 0.0017 0.0007 0.0048 0.0049 0.0457 0.0381 0.0817 0.0764 0.0489 0.0433 0.0740 0.0659 0.7430 0.7695 0.0002 0.0003 0.0007 0.0008 0.0019 0.0033 0.0107 0.0121 0.0534 0.0598 0.0963 0.1052 0.0590 0.0678 0.0919 0.0965 0.6858 0.6543 0.0000 0.0008 0.0017 0.0079 0.0480 0.0926 0.0499 0.0801 0.7189
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 889 579 image if available 5344 14258 479.3 73.36 59.66 126.81 384 417 439 460 479 496 514 540 582 0.0560 799 1.214 72.84 31.83 1 0.0378 202 0.0020 11.27 6.511 0.3208 235079.0
118000000
60300000000
31500000000000
0.4020 0.2453 0.0002 0.0000 0.0005 0.0000 0.0014 0.0000 0.0066 0.0002 0.0216 0.0122 0.0337 0.0213 0.0309 0.0112 0.0475 0.0182 0.8575 0.9369 0.0000 0.0000 0.0000 0.0000 0.0002 0.0000 0.0021 0.0002 0.0127 0.0122 0.0206 0.0213 0.0145 0.0112 0.0247 0.0167 0.9252 0.9384 0.0000 1.0000 0.0232 0.0000 0.0066 0.0000 0.0381 0.0000 0.0381 0.0000 0.0614 0.0000 0.0779 0.0000 0.0962 0.0000 0.6584 0.0000 0.0019 0.0026 0.0071 0.0160 0.0360 0.0527 0.0605 0.0854 0.7379 6 7 8 9 11 14 23 58 184 0.1961 6.16 3.029 0.6633 19637.6
11000000
8130000000
7350000000000
0.5394 0.1197 0.0721 0.0088 0.1081 0.0431 0.2450 0.1186 0.1766 0.0958 0.1315 0.1511 0.1045 0.1722 0.0829 0.1178 0.0541 0.1283 0.0252 0.1643 0.0010 0.0000 0.0013 0.0011 0.0048 0.0056 0.0166 0.0189 0.0507 0.0498 0.0842 0.0715 0.0555 0.0540 0.0778 0.0791 0.7083 0.7200 0.0008 0.0004 0.0027 0.0029 0.0023 0.0037 0.0139 0.0166 0.0616 0.0605 0.0953 0.0957 0.0581 0.0609 0.0817 0.0787 0.6836 0.6807 0.0007 0.0021 0.0021 0.0220 0.0535 0.0839 0.0676 0.0740 0.6941
SK-BR-3 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 1207 207 image if available 6980 19624 335.7 74.32 299.24 411.18 218 282 315 337 355 370 382 395 412 0.0495 972 0.878 105.01 22.67 2 0.0338 236 0.0016 18.87 6.802 0.2595 118201.0
43000000
16000000000
6030000000000
0.3992 0.2312 0.0008 0.0000 0.0019 0.0000 0.0057 0.0000 0.0151 0.0005 0.0362 0.0109 0.0496 0.0198 0.0603 0.0114 0.1042 0.0181 0.7262 0.9392 0.0000 0.0000 0.0000 0.0000 0.0003 0.0000 0.0033 0.0005 0.0117 0.0106 0.0200 0.0197 0.0164 0.0105 0.0219 0.0154 0.9264 0.9434 0.0234 0.1429 0.0263 0.0000 0.0536 0.4286 0.0623 0.2857 0.0837 0.1429 0.1003 0.0000 0.1120 0.0000 0.1324 0.0000 0.4060 0.0000 0.0007 0.0016 0.0028 0.0094 0.0211 0.0392 0.0446 0.0634 0.8170 12 16 20 28 78 180 350 599 943 0.0721 64.70 5.520 0.4930 258610.0
294000000
385000000000
559000000000000
0.4020 0.2305 0.0543 0.0023 0.2124 0.0098 0.3077 0.0976 0.1647 0.1574 0.1179 0.2237 0.0828 0.2003 0.0326 0.1140 0.0217 0.0910 0.0059 0.1039 0.0003 0.0000 0.0001 0.0001 0.0013 0.0004 0.0073 0.0059 0.0473 0.0415 0.0872 0.0708 0.0574 0.0514 0.0844 0.0737 0.7147 0.7561 0.0003 0.0002 0.0014 0.0008 0.0026 0.0025 0.0115 0.0140 0.0574 0.0661 0.1058 0.1190 0.0739 0.0814 0.1015 0.1092 0.6456 0.6068 0.0002 0.0005 0.0011 0.0070 0.0580 0.0920 0.0640 0.0926 0.6846
MDA-MB-231 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 673 661 image if available 8356 21692 629.4 88.97 157.77 200.04 505 558 588 612 637 660 678 703 736 0.0423 917 1.088 108.30 37.05 1 0.0333 278 0.0009 30.54 7.337 0.2196 404042.0
264000000
175000000000
118000000000000
0.4222 0.2219 0.0003 0.0000 0.0004 0.0000 0.0007 0.0000 0.0036 0.0002 0.0168 0.0091 0.0339 0.0170 0.0309 0.0087 0.0431 0.0141 0.8703 0.9508 0.0000 0.0000 0.0000 0.0000 0.0003 0.0000 0.0017 0.0002 0.0097 0.0091 0.0211 0.0170 0.0174 0.0087 0.0212 0.0141 0.9286 0.9508 0.0052 0.0000 0.0087 0.0000 0.0280 0.0000 0.0332 0.0000 0.0769 0.0000 0.1206 0.0000 0.0962 0.0000 0.1521 0.0000 0.4790 0.0000 0.0011 0.0031 0.0058 0.0105 0.0285 0.0524 0.0515 0.0731 0.7740 10 13 19 33 63 113 189 289 461 0.0633 29.43 5.277 0.5302 64906.9
36700000
24600000000
18400000000000
0.4278 0.2001 0.0270 0.0020 0.1224 0.0151 0.2282 0.0660 0.1787 0.1115 0.1483 0.1596 0.1201 0.2156 0.0684 0.1388 0.0615 0.1073 0.0454 0.1841 0.0001 0.0003 0.0002 0.0008 0.0015 0.0014 0.0077 0.0098 0.0437 0.0330 0.0678 0.0540 0.0479 0.0450 0.0793 0.0589 0.7519 0.7967 0.0005 0.0000 0.0015 0.0012 0.0026 0.0031 0.0122 0.0151 0.0611 0.0727 0.0953 0.1124 0.0662 0.0769 0.1035 0.1141 0.6570 0.6045 0.0001 0.0010 0.0024 0.0121 0.0486 0.0835 0.0554 0.0881 0.7087
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 937 792 image if available 9123 21746 335.0 60.34 75.58 106.02 251 283 304 322 338 352 368 385 407 0.0469 1020 1.203 88.96 31.32 2 0.0240 219 0.0031 5.79 6.087 0.3990 115860.0
41200000
15100000000
5640000000000
0.3775 0.2592 0.0006 0.0000 0.0019 0.0001 0.0030 0.0007 0.0099 0.0012 0.0231 0.0099 0.0367 0.0248 0.0410 0.0160 0.0611 0.0234 0.8226 0.9239 0.0001 0.0000 0.0004 0.0000 0.0010 0.0003 0.0037 0.0008 0.0116 0.0086 0.0156 0.0195 0.0156 0.0089 0.0230 0.0132 0.9290 0.9487 0.0127 0.0397 0.0136 0.0397 0.0363 0.1429 0.0417 0.1190 0.0644 0.1587 0.0816 0.1905 0.0743 0.0635 0.0988 0.0952 0.5766 0.1508 0.0021 0.0040 0.0109 0.0129 0.0253 0.0322 0.0430 0.0670 0.8026 6 7 9 13 26 46 79 134 219 0.0597 7.19 4.039 0.5263 16952.4
5760000
2510000000
1300000000000
0.3182 0.3239 0.0564 0.0038 0.1472 0.0263 0.2620 0.0928 0.1675 0.1276 0.1368 0.1702 0.0969 0.1688 0.0595 0.1401 0.0485 0.1159 0.0252 0.1545 0.0001 0.0005 0.0012 0.0006 0.0032 0.0031 0.0151 0.0112 0.0474 0.0451 0.0827 0.0582 0.0582 0.0542 0.0838 0.0756 0.7083 0.7517 0.0012 0.0002 0.0012 0.0019 0.0027 0.0043 0.0211 0.0249 0.0642 0.0784 0.1127 0.1071 0.0701 0.0779 0.0991 0.1155 0.6278 0.5898 0.0006 0.0010 0.0024 0.0164 0.0621 0.0942 0.0691 0.0956 0.6587
MDA-MB-231 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 708 397 image if available 15447 27394 562.4 113.78 118.30 212.73 394 458 507 542 576 606 636 667 703 0.0495 1356 0.896 108.19 30.00 3 0.0188 291 0.0006 29.72 7.605 0.2191 329218.0
199000000
124000000000
78600000000000
0.3988 0.2308 0.0014 0.0000 0.0019 0.0001 0.0040 0.0004 0.0105 0.0011 0.0269 0.0087 0.0473 0.0169 0.0485 0.0102 0.0672 0.0157 0.7922 0.9469 0.0001 0.0000 0.0002 0.0000 0.0005 0.0001 0.0023 0.0010 0.0107 0.0080 0.0188 0.0166 0.0160 0.0091 0.0204 0.0143 0.9310 0.9510 0.0029 0.0000 0.0095 0.0179 0.0147 0.0536 0.0297 0.1607 0.0612 0.1250 0.0718 0.1071 0.0872 0.2500 0.1213 0.1071 0.6015 0.1786 0.0008 0.0010 0.0032 0.0069 0.0226 0.0401 0.0411 0.0534 0.8309 7 9 10 11 12 15 40 206 467 0.3132 20.18 3.462 0.7115 59247.2
38200000
27600000000
21600000000000
0.5023 0.1444 0.0436 0.0036 0.1336 0.0128 0.2377 0.1026 0.1744 0.1354 0.1547 0.1810 0.1069 0.1882 0.0675 0.1055 0.0520 0.1119 0.0295 0.1589 0.0000 0.0003 0.0003 0.0004 0.0010 0.0004 0.0058 0.0038 0.0203 0.0189 0.0418 0.0353 0.0301 0.0220 0.0517 0.0418 0.8491 0.8771 0.0000 0.0000 0.0006 0.0005 0.0003 0.0005 0.0058 0.0079 0.0263 0.0302 0.0558 0.0631 0.0452 0.0492 0.0622 0.0705 0.8037 0.7782 0.0000 0.0000 0.0006 0.0049 0.0263 0.0486 0.0405 0.0571 0.8221
MDA-MB-231 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 305 753 image if available 14531 31502 446.4 61.03 117.13 162.48 365 402 424 439 452 464 476 491 515 0.0488 1538 0.844 110.02 27.80 4 0.0189 274 0.0017 18.96 6.823 0.2707 202963.0
93800000
44000000000
21000000000000
0.4307 0.2135 0.0003 0.0001 0.0001 0.0000 0.0009 0.0000 0.0036 0.0001 0.0149 0.0077 0.0284 0.0166 0.0253 0.0080 0.0383 0.0128 0.8882 0.9547 0.0001 0.0001 0.0000 0.0000 0.0000 0.0000 0.0019 0.0001 0.0098 0.0077 0.0186 0.0166 0.0149 0.0080 0.0188 0.0117 0.9360 0.9558 0.0148 1.0000 0.0239 0.0000 0.0091 0.0000 0.0262 0.0000 0.0809 0.0000 0.0945 0.0000 0.0809 0.0000 0.1173 0.0000 0.5524 0.0000 0.0022 0.0070 0.0123 0.0187 0.0346 0.0523 0.0642 0.0921 0.7167 13 16 21 33 52 79 118 180 305 0.0400 19.55 4.937 0.5597 40119.5
22800000
16800000000
14600000000000
0.4801 0.1897 0.0180 0.0019 0.0684 0.0102 0.1417 0.0304 0.1389 0.0605 0.1660 0.1385 0.1648 0.1775 0.1107 0.1263 0.1041 0.1394 0.0873 0.3154 0.0012 0.0003 0.0022 0.0020 0.0034 0.0030 0.0115 0.0124 0.0463 0.0387 0.0745 0.0614 0.0495 0.0472 0.0766 0.0656 0.7348 0.7694 0.0005 0.0007 0.0024 0.0020 0.0066 0.0068 0.0187 0.0217 0.0585 0.0622 0.0953 0.1084 0.0633 0.0699 0.0954 0.0979 0.6595 0.6304 0.0004 0.0017 0.0044 0.0151 0.0498 0.0888 0.0599 0.0831 0.6968
BT-20 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 923 749 image if available 18485 19144 337.4 48.91 148.53 162.19 268 300 318 331 344 355 367 380 396 0.0705 1349 1.142 100.72 39.20 2 0.0147 271 0.0025 9.90 6.327 0.3429 116234.0
40800000
14500000000
5230000000000
0.4218 0.2181 0.0005 0.0000 0.0012 0.0001 0.0027 0.0001 0.0083 0.0008 0.0174 0.0071 0.0285 0.0145 0.0316 0.0074 0.0551 0.0119 0.8546 0.9581 0.0001 0.0000 0.0000 0.0001 0.0005 0.0001 0.0022 0.0008 0.0085 0.0071 0.0136 0.0145 0.0122 0.0074 0.0186 0.0119 0.9443 0.9581 0.0326 0.0000 0.0692 0.0000 0.0794 0.0000 0.1090 0.0000 0.1517 0.0000 0.1415 0.0000 0.1395 0.0000 0.1446 0.0000 0.1324 0.0000 0.0028 0.0050 0.0091 0.0138 0.0293 0.0412 0.0457 0.0737 0.7793 23 31 42 57 77 109 167 256 387 0.0183 13.36 5.441 0.5104 48364.8
22700000
12800000000
8140000000000
0.3890 0.2609 0.0233 0.0013 0.0952 0.0085 0.1700 0.0530 0.1578 0.1011 0.1966 0.1512 0.1445 0.1702 0.0908 0.1386 0.0714 0.1404 0.0504 0.2358 0.0001 0.0003 0.0008 0.0009 0.0026 0.0044 0.0128 0.0124 0.0492 0.0417 0.0708 0.0661 0.0547 0.0448 0.0827 0.0706 0.7262 0.7587 0.0007 0.0006 0.0009 0.0017 0.0035 0.0058 0.0196 0.0235 0.0581 0.0707 0.0989 0.0946 0.0629 0.0773 0.0941 0.1006 0.6612 0.6252 0.0000 0.0010 0.0043 0.0159 0.0522 0.0864 0.0570 0.0870 0.6963