High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 781 | 933 | 4650 | 7671 | 149.2 | 35.80 | 272.55 | 157.57 | 110 | 120 | 127 | 134 | 142 | 151 | 162 | 176 | 198 | 0.0948 | 727 | 1.075 | 97.75 | 27.80 | 1 | 0.0520 | 242 | 0.0020 | 26.81 | 6.558 | 0.2363 | 23531.1 | 3940000 | 699000000 | 132000000000 | 0.4493 | 0.1999 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0104 | 0.0002 | 0.0338 | 0.0009 | 0.0898 | 0.0243 | 0.1628 | 0.0471 | 0.1597 | 0.0468 | 0.1837 | 0.0695 | 0.3577 | 0.8111 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0002 | 0.0118 | 0.0004 | 0.0454 | 0.0150 | 0.0668 | 0.0232 | 0.0778 | 0.0163 | 0.1088 | 0.0306 | 0.6864 | 0.9142 | 0.0023 | 0.0030 | 0.0092 | 0.0060 | 0.0358 | 0.0329 | 0.0796 | 0.0928 | 0.1476 | 0.1707 | 0.1857 | 0.2335 | 0.1153 | 0.1138 | 0.1361 | 0.1707 | 0.2884 | 0.1766 | 0.0020 | 0.0035 | 0.0111 | 0.0308 | 0.0968 | 0.1402 | 0.1160 | 0.1452 | 0.4544 | 91 | 134 | 171 | 208 | 247 | 291 | 338 | 395 | 486 | 0.0007 | 96.75 | 7.538 | 0.1758 | 99105.9 | 44100000 | 22800000000 | 13300000000000 | 0.5485 | 0.1214 | 0.0151 | 0.0008 | 0.0764 | 0.0058 | 0.1871 | 0.0233 | 0.1861 | 0.0595 | 0.2027 | 0.1375 | 0.1554 | 0.2135 | 0.0941 | 0.1857 | 0.0520 | 0.1666 | 0.0312 | 0.2074 | 0.0009 | 0.0002 | 0.0030 | 0.0007 | 0.0077 | 0.0036 | 0.0219 | 0.0100 | 0.0743 | 0.0552 | 0.1272 | 0.1019 | 0.1078 | 0.0886 | 0.1429 | 0.1166 | 0.5144 | 0.6232 | 0.0008 | 0.0053 | 0.0106 | 0.0148 | 0.0203 | 0.0373 | 0.0519 | 0.0841 | 0.1339 | 0.1587 | 0.1729 | 0.1829 | 0.1303 | 0.1533 | 0.1652 | 0.1385 | 0.3141 | 0.2250 | 0.0009 | 0.0051 | 0.0146 | 0.0363 | 0.0991 | 0.1479 | 0.1303 | 0.1511 | 0.4148 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1092 | 85 | 5449 | 11450 | 95.0 | 23.16 | 86.45 | 60.42 | 71 | 77 | 81 | 86 | 91 | 95 | 101 | 110 | 125 | 0.0779 | 892 | 0.747 | 88.84 | 18.03 | 1 | 0.0376 | 205 | 0.0045 | 11.97 | 5.782 | 0.3166 | 9560.2 | 1030000 | 119000000 | 14900000000 | 0.4517 | 0.1982 | 0.0017 | 0.0000 | 0.0031 | 0.0000 | 0.0068 | 0.0002 | 0.0214 | 0.0018 | 0.0749 | 0.0225 | 0.1219 | 0.0393 | 0.1611 | 0.0466 | 0.2022 | 0.0826 | 0.4069 | 0.8069 | 0.0013 | 0.0000 | 0.0016 | 0.0000 | 0.0029 | 0.0000 | 0.0120 | 0.0006 | 0.0334 | 0.0144 | 0.0484 | 0.0215 | 0.0776 | 0.0164 | 0.1074 | 0.0354 | 0.7154 | 0.9118 | 0.0096 | 0.0216 | 0.0160 | 0.0377 | 0.0310 | 0.0377 | 0.0652 | 0.0970 | 0.1485 | 0.1375 | 0.1485 | 0.1563 | 0.1239 | 0.1186 | 0.1528 | 0.1456 | 0.3045 | 0.2480 | 0.0022 | 0.0066 | 0.0254 | 0.0521 | 0.0902 | 0.1139 | 0.1248 | 0.1323 | 0.4525 | 21 | 33 | 45 | 59 | 73 | 90 | 110 | 133 | 169 | 0.0064 | 12.20 | 5.702 | 0.3894 | 11125.0 | 1840000 | 360000000 | 80100000000 | 0.5551 | 0.1175 | 0.0169 | 0.0024 | 0.0852 | 0.0089 | 0.1933 | 0.0316 | 0.2046 | 0.0842 | 0.1860 | 0.1444 | 0.1445 | 0.1944 | 0.0848 | 0.1671 | 0.0580 | 0.1675 | 0.0268 | 0.1994 | 0.0005 | 0.0011 | 0.0025 | 0.0020 | 0.0062 | 0.0051 | 0.0237 | 0.0164 | 0.0697 | 0.0496 | 0.1043 | 0.0775 | 0.0994 | 0.0776 | 0.1410 | 0.1147 | 0.5528 | 0.6561 | 0.0008 | 0.0052 | 0.0066 | 0.0098 | 0.0138 | 0.0265 | 0.0517 | 0.0622 | 0.1115 | 0.1306 | 0.1502 | 0.1614 | 0.1351 | 0.1383 | 0.1523 | 0.1453 | 0.3780 | 0.3206 | 0.0019 | 0.0031 | 0.0080 | 0.0331 | 0.0932 | 0.1245 | 0.1171 | 0.1566 | 0.4623 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1212 | 702 | 5868 | 12257 | 385.4 | 94.46 | 91.78 | 170.82 | 273 | 308 | 334 | 356 | 378 | 400 | 426 | 456 | 508 | 0.0725 | 889 | 0.820 | 133.03 | 29.02 | 1 | 0.0525 | 308 | 0.0009 | 48.18 | 7.294 | 0.1744 | 157465.0 | 68100000 | 31100000000 | 15000000000000 | 0.4263 | 0.2176 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0050 | 0.0000 | 0.0146 | 0.0017 | 0.0737 | 0.0220 | 0.1277 | 0.0422 | 0.1348 | 0.0429 | 0.1681 | 0.0602 | 0.4758 | 0.8309 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0051 | 0.0012 | 0.0272 | 0.0110 | 0.0596 | 0.0230 | 0.0531 | 0.0165 | 0.0768 | 0.0232 | 0.7767 | 0.9251 | 0.0028 | 0.0078 | 0.0102 | 0.0078 | 0.0186 | 0.0234 | 0.0743 | 0.0807 | 0.1188 | 0.2083 | 0.1541 | 0.1823 | 0.1086 | 0.1302 | 0.1374 | 0.1458 | 0.3751 | 0.2135 | 0.0007 | 0.0040 | 0.0051 | 0.0279 | 0.0729 | 0.1056 | 0.0990 | 0.1273 | 0.5575 | 7 | 9 | 11 | 13 | 23 | 44 | 79 | 121 | 232 | 0.1438 | 16.26 | 4.064 | 0.6574 | 37599.5 | 27100000 | 24500000000 | 25000000000000 | 0.6211 | 0.0732 | 0.0189 | 0.0060 | 0.0763 | 0.0189 | 0.1346 | 0.0570 | 0.1235 | 0.0607 | 0.1672 | 0.1072 | 0.1475 | 0.1449 | 0.1321 | 0.1357 | 0.0978 | 0.1670 | 0.1021 | 0.3027 | 0.0003 | 0.0007 | 0.0023 | 0.0013 | 0.0031 | 0.0029 | 0.0135 | 0.0108 | 0.0595 | 0.0421 | 0.0868 | 0.0731 | 0.0634 | 0.0576 | 0.0964 | 0.0886 | 0.6746 | 0.7230 | 0.0007 | 0.0013 | 0.0030 | 0.0031 | 0.0071 | 0.0101 | 0.0213 | 0.0312 | 0.0832 | 0.0810 | 0.1153 | 0.1192 | 0.0735 | 0.0880 | 0.1138 | 0.1016 | 0.5822 | 0.5645 | 0.0006 | 0.0037 | 0.0095 | 0.0224 | 0.0610 | 0.1046 | 0.0742 | 0.1126 | 0.6114 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 357 | 710 | 4921 | 10409 | 582.7 | 104.04 | 163.34 | 169.37 | 446 | 495 | 525 | 552 | 579 | 603 | 634 | 667 | 722 | 0.0790 | 822 | 1.185 | 96.46 | 39.82 | 1 | 0.0528 | 260 | 0.0007 | 60.83 | 7.459 | 0.1592 | 350308.0 | 217000000 | 138000000000 | 90400000000000 | 0.4237 | 0.2197 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0017 | 0.0004 | 0.0084 | 0.0015 | 0.0427 | 0.0174 | 0.0858 | 0.0245 | 0.0936 | 0.0272 | 0.1375 | 0.0367 | 0.6295 | 0.8923 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0031 | 0.0002 | 0.0252 | 0.0151 | 0.0417 | 0.0191 | 0.0370 | 0.0165 | 0.0620 | 0.0242 | 0.8301 | 0.9248 | 0.0075 | 0.0326 | 0.0090 | 0.0000 | 0.0271 | 0.0761 | 0.0827 | 0.1739 | 0.1203 | 0.1739 | 0.1399 | 0.2391 | 0.1068 | 0.1413 | 0.1053 | 0.1087 | 0.4015 | 0.0543 | 0.0017 | 0.0034 | 0.0029 | 0.0253 | 0.0623 | 0.1077 | 0.1098 | 0.1355 | 0.5513 | 11 | 14 | 21 | 52 | 104 | 160 | 229 | 315 | 422 | 0.0230 | 43.80 | 6.033 | 0.3963 | 55363.2 | 23600000 | 11400000000 | 6020000000000 | 0.5634 | 0.1337 | 0.0386 | 0.0005 | 0.1929 | 0.0101 | 0.2671 | 0.0648 | 0.1977 | 0.1411 | 0.1244 | 0.2046 | 0.0839 | 0.1945 | 0.0473 | 0.1177 | 0.0260 | 0.1172 | 0.0222 | 0.1494 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0024 | 0.0004 | 0.0120 | 0.0066 | 0.0468 | 0.0368 | 0.0843 | 0.0643 | 0.0646 | 0.0509 | 0.1058 | 0.0885 | 0.6839 | 0.7518 | 0.0008 | 0.0003 | 0.0011 | 0.0016 | 0.0036 | 0.0038 | 0.0149 | 0.0166 | 0.0618 | 0.0787 | 0.1118 | 0.1234 | 0.0845 | 0.0918 | 0.1220 | 0.1321 | 0.5995 | 0.5516 | 0.0005 | 0.0010 | 0.0027 | 0.0124 | 0.0553 | 0.0981 | 0.0694 | 0.1131 | 0.6476 | |||
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 951 | 130 | 6472 | 11634 | 104.2 | 26.74 | 134.36 | 144.55 | 75 | 82 | 88 | 93 | 99 | 106 | 114 | 124 | 140 | 0.0675 | 785 | 1.222 | 77.80 | 31.00 | 1 | 0.0311 | 201 | 0.0033 | 14.98 | 6.074 | 0.2909 | 11575.5 | 1380000 | 176000000 | 24100000000 | 0.4404 | 0.2109 | 0.0008 | 0.0000 | 0.0067 | 0.0000 | 0.0180 | 0.0003 | 0.0355 | 0.0049 | 0.0968 | 0.0225 | 0.1552 | 0.0473 | 0.1791 | 0.0458 | 0.2071 | 0.0729 | 0.3007 | 0.8063 | 0.0002 | 0.0000 | 0.0028 | 0.0000 | 0.0058 | 0.0002 | 0.0154 | 0.0008 | 0.0436 | 0.0128 | 0.0690 | 0.0233 | 0.0790 | 0.0166 | 0.1135 | 0.0378 | 0.6708 | 0.9086 | 0.0078 | 0.0060 | 0.0132 | 0.0302 | 0.0296 | 0.0302 | 0.0685 | 0.0867 | 0.1401 | 0.1512 | 0.1556 | 0.2198 | 0.1222 | 0.1109 | 0.1362 | 0.1431 | 0.3268 | 0.2218 | 0.0014 | 0.0074 | 0.0159 | 0.0337 | 0.0708 | 0.1173 | 0.1045 | 0.1399 | 0.5090 | 11 | 17 | 27 | 47 | 80 | 123 | 170 | 236 | 349 | 0.0095 | 68.36 | 6.495 | 0.3320 | 38946.3 | 15400000 | 7190000000 | 3780000000000 | 0.5106 | 0.1580 | 0.0359 | 0.0011 | 0.1272 | 0.0129 | 0.2289 | 0.0620 | 0.1945 | 0.1073 | 0.1660 | 0.1675 | 0.1137 | 0.2080 | 0.0666 | 0.1442 | 0.0449 | 0.1357 | 0.0224 | 0.1612 | 0.0002 | 0.0000 | 0.0004 | 0.0005 | 0.0036 | 0.0015 | 0.0120 | 0.0079 | 0.0557 | 0.0459 | 0.0946 | 0.0834 | 0.0802 | 0.0594 | 0.1058 | 0.0943 | 0.6476 | 0.7070 | 0.0003 | 0.0013 | 0.0024 | 0.0032 | 0.0089 | 0.0084 | 0.0282 | 0.0316 | 0.0805 | 0.0832 | 0.1194 | 0.1342 | 0.0982 | 0.1048 | 0.1210 | 0.1303 | 0.5413 | 0.5031 | 0.0002 | 0.0014 | 0.0041 | 0.0182 | 0.0668 | 0.1165 | 0.0832 | 0.1178 | 0.5918 | |||
MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 591 | 322 | 3805 | 8120 | 447.6 | 140.46 | 62.41 | 102.20 | 225 | 309 | 397 | 453 | 481 | 505 | 531 | 568 | 598 | 0.0792 | 643 | 1.179 | 95.75 | 35.78 | 2 | 0.0636 | 242 | 0.0012 | 24.22 | 7.023 | 0.2589 | 220069.0 | 114000000 | 61800000000 | 34400000000000 | 0.3868 | 0.2449 | 0.0017 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0003 | 0.0114 | 0.0030 | 0.0542 | 0.0207 | 0.0787 | 0.0353 | 0.0685 | 0.0267 | 0.1038 | 0.0443 | 0.6805 | 0.8697 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0019 | 0.0183 | 0.0158 | 0.0254 | 0.0260 | 0.0183 | 0.0167 | 0.0268 | 0.0236 | 0.9097 | 0.9160 | 0.0009 | 0.0000 | 0.0037 | 0.0000 | 0.0083 | 0.0000 | 0.0111 | 0.0000 | 0.0426 | 0.0000 | 0.0546 | 0.0000 | 0.0592 | 0.0000 | 0.0823 | 0.0000 | 0.7373 | 1.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0047 | 0.0236 | 0.0356 | 0.0347 | 0.0592 | 0.8404 | 8 | 9 | 11 | 12 | 16 | 24 | 45 | 91 | 190 | 0.1789 | 5.12 | 3.242 | 0.6875 | 14337.8 | 5250000 | 2370000000 | 1220000000000 | 0.6067 | 0.0913 | 0.0581 | 0.0060 | 0.1183 | 0.0249 | 0.1618 | 0.0957 | 0.1390 | 0.1256 | 0.1784 | 0.1446 | 0.1515 | 0.1605 | 0.1224 | 0.1296 | 0.0456 | 0.0987 | 0.0249 | 0.2144 | 0.0017 | 0.0015 | 0.0035 | 0.0026 | 0.0035 | 0.0045 | 0.0138 | 0.0146 | 0.0558 | 0.0544 | 0.0878 | 0.0773 | 0.0636 | 0.0484 | 0.0930 | 0.0926 | 0.6775 | 0.7041 | 0.0005 | 0.0006 | 0.0005 | 0.0006 | 0.0033 | 0.0024 | 0.0169 | 0.0192 | 0.0754 | 0.0800 | 0.1038 | 0.1191 | 0.0644 | 0.0565 | 0.1032 | 0.1179 | 0.6319 | 0.6037 | 0.0010 | 0.0034 | 0.0039 | 0.0186 | 0.0658 | 0.0932 | 0.0677 | 0.0991 | 0.6472 | |
MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 976 | 656 | 13290 | 29012 | 350.5 | 83.54 | 117.42 | 202.47 | 252 | 284 | 306 | 327 | 348 | 369 | 393 | 419 | 457 | 0.0458 | 1328 | 1.206 | 145.66 | 51.35 | 3 | 0.0266 | 354 | 0.0009 | 33.81 | 7.228 | 0.1932 | 129853.0 | 50400000 | 20400000000 | 8570000000000 | 0.4626 | 0.1869 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0137 | 0.0009 | 0.0626 | 0.0154 | 0.1394 | 0.0357 | 0.1429 | 0.0364 | 0.1618 | 0.0560 | 0.4786 | 0.8556 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0047 | 0.0002 | 0.0239 | 0.0104 | 0.0583 | 0.0216 | 0.0527 | 0.0167 | 0.0693 | 0.0259 | 0.7910 | 0.9253 | 0.0016 | 0.0134 | 0.0070 | 0.0202 | 0.0147 | 0.0353 | 0.0609 | 0.1109 | 0.1230 | 0.1681 | 0.1707 | 0.1983 | 0.1145 | 0.1059 | 0.1486 | 0.1345 | 0.3589 | 0.2134 | 0.0002 | 0.0012 | 0.0066 | 0.0185 | 0.0678 | 0.1107 | 0.0917 | 0.1206 | 0.5827 | 6 | 7 | 9 | 10 | 12 | 24 | 88 | 206 | 406 | 0.1454 | 15.57 | 3.922 | 0.5837 | 54782.0 | 35700000 | 27800000000 | 24300000000000 | 0.5329 | 0.1352 | 0.0637 | 0.0030 | 0.1850 | 0.0394 | 0.2305 | 0.1421 | 0.1607 | 0.1285 | 0.1562 | 0.1739 | 0.0925 | 0.1834 | 0.0652 | 0.1156 | 0.0326 | 0.0940 | 0.0136 | 0.1201 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0018 | 0.0013 | 0.0098 | 0.0088 | 0.0421 | 0.0384 | 0.0678 | 0.0575 | 0.0453 | 0.0456 | 0.0680 | 0.0641 | 0.7645 | 0.7842 | 0.0000 | 0.0003 | 0.0004 | 0.0007 | 0.0017 | 0.0025 | 0.0116 | 0.0124 | 0.0523 | 0.0544 | 0.0850 | 0.0971 | 0.0615 | 0.0646 | 0.0847 | 0.0903 | 0.7028 | 0.6776 | 0.0004 | 0.0005 | 0.0019 | 0.0076 | 0.0494 | 0.0725 | 0.0487 | 0.0795 | 0.7395 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 456 | 893 | 7298 | 7323 | 187.1 | 41.22 | 216.83 | 133.57 | 140 | 153 | 163 | 172 | 181 | 191 | 203 | 217 | 241 | 0.1269 | 929 | 1.120 | 100.70 | 34.44 | 2 | 0.0340 | 248 | 0.0013 | 39.38 | 6.942 | 0.1916 | 36690.8 | 7560000 | 1640000000 | 376000000000 | 0.4324 | 0.2088 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0047 | 0.0003 | 0.0179 | 0.0010 | 0.0803 | 0.0227 | 0.1350 | 0.0383 | 0.1477 | 0.0424 | 0.1875 | 0.0685 | 0.4263 | 0.8267 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0059 | 0.0001 | 0.0393 | 0.0136 | 0.0647 | 0.0208 | 0.0718 | 0.0167 | 0.1034 | 0.0300 | 0.7137 | 0.9187 | 0.0101 | 0.0100 | 0.0135 | 0.0376 | 0.0262 | 0.0526 | 0.0760 | 0.1153 | 0.1529 | 0.1980 | 0.1782 | 0.1930 | 0.1275 | 0.1454 | 0.1579 | 0.1103 | 0.2576 | 0.1378 | 0.0021 | 0.0043 | 0.0092 | 0.0374 | 0.0860 | 0.1310 | 0.1127 | 0.1396 | 0.4776 | 63 | 92 | 126 | 158 | 191 | 228 | 275 | 332 | 409 | 0.0011 | 78.81 | 7.283 | 0.1845 | 64856.6 | 23800000 | 10100000000 | 4840000000000 | 0.5256 | 0.1334 | 0.0183 | 0.0013 | 0.0889 | 0.0097 | 0.2296 | 0.0405 | 0.1967 | 0.0866 | 0.1778 | 0.1704 | 0.1364 | 0.2228 | 0.0944 | 0.1556 | 0.0384 | 0.1403 | 0.0195 | 0.1729 | 0.0015 | 0.0002 | 0.0025 | 0.0028 | 0.0091 | 0.0054 | 0.0269 | 0.0191 | 0.0793 | 0.0611 | 0.1299 | 0.1025 | 0.1089 | 0.0860 | 0.1316 | 0.1112 | 0.5104 | 0.6118 | 0.0033 | 0.0033 | 0.0066 | 0.0076 | 0.0166 | 0.0239 | 0.0439 | 0.0631 | 0.1159 | 0.1430 | 0.1718 | 0.1816 | 0.1308 | 0.1294 | 0.1320 | 0.1457 | 0.3791 | 0.3023 | 0.0009 | 0.0060 | 0.0160 | 0.0393 | 0.0978 | 0.1494 | 0.1142 | 0.1324 | 0.4439 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 120 | 655 | 4898 | 6342 | 156.3 | 38.66 | 125.03 | 113.06 | 113 | 124 | 133 | 141 | 150 | 159 | 170 | 185 | 209 | 0.1042 | 661 | 1.120 | 87.09 | 35.00 | 2 | 0.0484 | 237 | 0.0016 | 33.19 | 6.724 | 0.2162 | 25917.2 | 4580000 | 862000000 | 173000000000 | 0.4020 | 0.2430 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0088 | 0.0004 | 0.0371 | 0.0011 | 0.0856 | 0.0217 | 0.1540 | 0.0539 | 0.1540 | 0.0479 | 0.1891 | 0.0811 | 0.3701 | 0.7938 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0026 | 0.0002 | 0.0144 | 0.0004 | 0.0394 | 0.0127 | 0.0737 | 0.0281 | 0.0709 | 0.0168 | 0.1057 | 0.0388 | 0.6924 | 0.9028 | 0.0088 | 0.0056 | 0.0110 | 0.0056 | 0.0154 | 0.0504 | 0.0647 | 0.1148 | 0.1283 | 0.1961 | 0.1776 | 0.1905 | 0.1217 | 0.0812 | 0.1371 | 0.1204 | 0.3355 | 0.2353 | 0.0014 | 0.0066 | 0.0132 | 0.0448 | 0.0754 | 0.1273 | 0.1056 | 0.1165 | 0.5092 | 23 | 33 | 47 | 65 | 89 | 116 | 152 | 201 | 280 | 0.0060 | 36.94 | 6.174 | 0.3498 | 28413.7 | 9100000 | 3580000000 | 1620000000000 | 0.5069 | 0.1440 | 0.0282 | 0.0015 | 0.0796 | 0.0149 | 0.1823 | 0.0412 | 0.2034 | 0.0865 | 0.1601 | 0.1370 | 0.1511 | 0.1885 | 0.0987 | 0.1555 | 0.0564 | 0.1529 | 0.0403 | 0.2219 | 0.0014 | 0.0006 | 0.0003 | 0.0023 | 0.0061 | 0.0020 | 0.0215 | 0.0159 | 0.0617 | 0.0456 | 0.1159 | 0.0901 | 0.0829 | 0.0697 | 0.1265 | 0.1079 | 0.5837 | 0.6661 | 0.0015 | 0.0031 | 0.0077 | 0.0057 | 0.0113 | 0.0088 | 0.0381 | 0.0453 | 0.0959 | 0.1246 | 0.1562 | 0.1724 | 0.1113 | 0.1089 | 0.1572 | 0.1605 | 0.4206 | 0.3707 | 0.0004 | 0.0033 | 0.0075 | 0.0263 | 0.0889 | 0.1369 | 0.1039 | 0.1507 | 0.4821 | |
MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 989 | 569 | 11363 | 17154 | 435.1 | 102.14 | 100.15 | 106.92 | 319 | 350 | 374 | 396 | 420 | 445 | 475 | 519 | 577 | 0.0642 | 1102 | 1.214 | 111.97 | 45.88 | 1 | 0.0259 | 294 | 0.0008 | 45.10 | 7.457 | 0.1791 | 199761.0 | 96800000 | 49400000000 | 26500000000000 | 0.4356 | 0.2162 | 0.0004 | 0.0001 | 0.0023 | 0.0001 | 0.0049 | 0.0006 | 0.0187 | 0.0024 | 0.0547 | 0.0168 | 0.1228 | 0.0359 | 0.1224 | 0.0361 | 0.1532 | 0.0537 | 0.5207 | 0.8544 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0001 | 0.0074 | 0.0009 | 0.0262 | 0.0104 | 0.0589 | 0.0186 | 0.0605 | 0.0168 | 0.0788 | 0.0275 | 0.7659 | 0.9258 | 0.0027 | 0.0014 | 0.0063 | 0.0068 | 0.0094 | 0.0315 | 0.0367 | 0.0876 | 0.0823 | 0.1231 | 0.1360 | 0.1737 | 0.0922 | 0.1081 | 0.1128 | 0.1231 | 0.5217 | 0.3447 | 0.0010 | 0.0012 | 0.0068 | 0.0319 | 0.0806 | 0.1097 | 0.0930 | 0.1123 | 0.5635 | 7 | 11 | 20 | 37 | 62 | 94 | 132 | 180 | 248 | 0.0392 | 11.55 | 4.988 | 0.4732 | 21460.8 | 6340000 | 2300000000 | 971000000000 | 0.5515 | 0.1124 | 0.0581 | 0.0039 | 0.2164 | 0.0200 | 0.2885 | 0.1377 | 0.1593 | 0.1383 | 0.1259 | 0.1997 | 0.0867 | 0.1917 | 0.0344 | 0.1180 | 0.0237 | 0.1032 | 0.0070 | 0.0874 | 0.0001 | 0.0001 | 0.0005 | 0.0005 | 0.0012 | 0.0003 | 0.0130 | 0.0092 | 0.0667 | 0.0520 | 0.1087 | 0.0943 | 0.0812 | 0.0656 | 0.1186 | 0.1022 | 0.6099 | 0.6759 | 0.0005 | 0.0012 | 0.0010 | 0.0029 | 0.0045 | 0.0074 | 0.0218 | 0.0286 | 0.0939 | 0.1036 | 0.1590 | 0.1785 | 0.0997 | 0.1088 | 0.1431 | 0.1573 | 0.4763 | 0.4118 | 0.0003 | 0.0006 | 0.0018 | 0.0174 | 0.0781 | 0.1316 | 0.0944 | 0.1376 | 0.5381 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1182 | 506 | 5215 | 17071 | 251.9 | 54.05 | 103.06 | 163.53 | 180 | 201 | 217 | 233 | 250 | 266 | 282 | 302 | 327 | 0.0592 | 1011 | 1.075 | 113.14 | 33.02 | 1 | 0.0516 | 269 | 0.0008 | 48.54 | 7.272 | 0.1797 | 66392.4 | 18200000 | 5190000000 | 1520000000000 | 0.4330 | 0.2117 | 0.0006 | 0.0000 | 0.0022 | 0.0000 | 0.0048 | 0.0000 | 0.0275 | 0.0022 | 0.0797 | 0.0138 | 0.1232 | 0.0367 | 0.1331 | 0.0359 | 0.1574 | 0.0648 | 0.4715 | 0.8468 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0077 | 0.0012 | 0.0289 | 0.0106 | 0.0534 | 0.0245 | 0.0530 | 0.0168 | 0.0732 | 0.0315 | 0.7817 | 0.9154 | 0.0029 | 0.0373 | 0.0097 | 0.0683 | 0.0165 | 0.0683 | 0.0584 | 0.1739 | 0.1051 | 0.2050 | 0.1907 | 0.1801 | 0.1430 | 0.1180 | 0.1459 | 0.0745 | 0.3278 | 0.0745 | 0.0004 | 0.0027 | 0.0059 | 0.0212 | 0.0550 | 0.1037 | 0.0923 | 0.1127 | 0.6060 | 8 | 10 | 12 | 14 | 19 | 40 | 88 | 178 | 323 | 0.1315 | 17.54 | 4.370 | 0.5904 | 37361.8 | 20200000 | 13400000000 | 10300000000000 | 0.5718 | 0.1052 | 0.0904 | 0.0025 | 0.2461 | 0.0286 | 0.3176 | 0.1880 | 0.1451 | 0.1835 | 0.0925 | 0.1830 | 0.0641 | 0.1810 | 0.0273 | 0.0847 | 0.0137 | 0.0762 | 0.0032 | 0.0727 | 0.0004 | 0.0000 | 0.0008 | 0.0005 | 0.0013 | 0.0015 | 0.0144 | 0.0131 | 0.0649 | 0.0555 | 0.1011 | 0.0975 | 0.0663 | 0.0604 | 0.0930 | 0.0903 | 0.6578 | 0.6812 | 0.0005 | 0.0005 | 0.0016 | 0.0020 | 0.0060 | 0.0048 | 0.0196 | 0.0218 | 0.0670 | 0.0698 | 0.1097 | 0.1043 | 0.0649 | 0.0698 | 0.0947 | 0.0959 | 0.6360 | 0.6311 | 0.0004 | 0.0010 | 0.0042 | 0.0151 | 0.0692 | 0.1025 | 0.0681 | 0.0903 | 0.6491 | |
MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1168 | 424 | 6546 | 17083 | 401.6 | 88.26 | 135.51 | 179.85 | 299 | 325 | 346 | 367 | 388 | 411 | 439 | 479 | 531 | 0.0520 | 889 | 1.155 | 97.74 | 36.50 | 1 | 0.0390 | 255 | 0.0006 | 73.03 | 7.599 | 0.1457 | 169066.0 | 74500000 | 34300000000 | 16500000000000 | 0.4391 | 0.2054 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0024 | 0.0003 | 0.0156 | 0.0020 | 0.0721 | 0.0202 | 0.1564 | 0.0399 | 0.1454 | 0.0398 | 0.1652 | 0.0640 | 0.4415 | 0.8338 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0067 | 0.0003 | 0.0328 | 0.0108 | 0.0762 | 0.0234 | 0.0686 | 0.0168 | 0.0916 | 0.0321 | 0.7229 | 0.9166 | 0.0000 | 0.0086 | 0.0056 | 0.0115 | 0.0104 | 0.0576 | 0.0569 | 0.1124 | 0.1018 | 0.1960 | 0.1604 | 0.2219 | 0.1099 | 0.1441 | 0.1299 | 0.1210 | 0.4250 | 0.1268 | 0.0014 | 0.0056 | 0.0112 | 0.0352 | 0.0715 | 0.1141 | 0.0855 | 0.1018 | 0.5738 | 6 | 9 | 12 | 24 | 53 | 96 | 159 | 245 | 398 | 0.0690 | 25.10 | 5.074 | 0.4896 | 50707.9 | 26800000 | 17300000000 | 12900000000000 | 0.5220 | 0.1303 | 0.0750 | 0.0031 | 0.1918 | 0.0288 | 0.2725 | 0.1436 | 0.1472 | 0.1470 | 0.1168 | 0.1845 | 0.0842 | 0.1772 | 0.0566 | 0.1189 | 0.0340 | 0.0954 | 0.0219 | 0.1016 | 0.0002 | 0.0003 | 0.0006 | 0.0001 | 0.0031 | 0.0029 | 0.0159 | 0.0113 | 0.0618 | 0.0534 | 0.1096 | 0.0985 | 0.0694 | 0.0658 | 0.1005 | 0.0962 | 0.6390 | 0.6716 | 0.0004 | 0.0009 | 0.0024 | 0.0025 | 0.0050 | 0.0096 | 0.0203 | 0.0215 | 0.0764 | 0.0900 | 0.1299 | 0.1292 | 0.0772 | 0.0830 | 0.1085 | 0.1212 | 0.5799 | 0.5421 | 0.0004 | 0.0014 | 0.0042 | 0.0152 | 0.0716 | 0.1197 | 0.0695 | 0.1083 | 0.6097 | |
MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 389 | 150 | 4606 | 15170 | 424.9 | 103.36 | 120.09 | 186.60 | 306 | 339 | 363 | 386 | 408 | 432 | 458 | 507 | 588 | 0.0560 | 850 | 1.111 | 95.13 | 27.89 | 1 | 0.0480 | 221 | 0.0012 | 30.61 | 6.994 | 0.2232 | 191216.0 | 91000000 | 45700000000 | 24100000000000 | 0.4331 | 0.2087 | 0.0004 | 0.0000 | 0.0014 | 0.0005 | 0.0043 | 0.0024 | 0.0159 | 0.0046 | 0.0524 | 0.0246 | 0.1229 | 0.0476 | 0.1175 | 0.0410 | 0.1431 | 0.0659 | 0.5421 | 0.8134 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0027 | 0.0002 | 0.0087 | 0.0013 | 0.0278 | 0.0148 | 0.0578 | 0.0278 | 0.0602 | 0.0168 | 0.0801 | 0.0354 | 0.7618 | 0.9036 | 0.0011 | 0.0118 | 0.0078 | 0.0024 | 0.0111 | 0.0118 | 0.0277 | 0.0729 | 0.0632 | 0.0965 | 0.1164 | 0.1412 | 0.0510 | 0.1529 | 0.0854 | 0.1506 | 0.6364 | 0.3600 | 0.0035 | 0.0025 | 0.0122 | 0.0294 | 0.0704 | 0.1160 | 0.0821 | 0.1013 | 0.5826 | 7 | 9 | 12 | 15 | 24 | 53 | 116 | 205 | 380 | 0.0719 | 21.43 | 4.823 | 0.5539 | 49238.9 | 29200000 | 20700000000 | 16600000000000 | 0.4072 | 0.2209 | 0.0112 | 0.0005 | 0.0637 | 0.0029 | 0.1751 | 0.0280 | 0.2032 | 0.0619 | 0.1751 | 0.1581 | 0.1526 | 0.2116 | 0.1058 | 0.1654 | 0.0702 | 0.1537 | 0.0431 | 0.2180 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0014 | 0.0014 | 0.0111 | 0.0059 | 0.0296 | 0.0273 | 0.0544 | 0.0427 | 0.0464 | 0.0368 | 0.0657 | 0.0505 | 0.7911 | 0.8351 | 0.0010 | 0.0008 | 0.0003 | 0.0006 | 0.0025 | 0.0025 | 0.0113 | 0.0139 | 0.0420 | 0.0541 | 0.0795 | 0.0889 | 0.0566 | 0.0606 | 0.0881 | 0.0878 | 0.7186 | 0.6907 | 0.0004 | 0.0020 | 0.0047 | 0.0105 | 0.0368 | 0.0616 | 0.0504 | 0.0780 | 0.7555 | |||
BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 355 | 746 | 5178 | 14618 | 327.7 | 65.14 | 129.72 | 168.91 | 250 | 272 | 289 | 304 | 321 | 339 | 359 | 383 | 416 | 0.0483 | 706 | 1.223 | 132.20 | 48.33 | 1 | 0.0624 | 323 | 0.0006 | 79.47 | 7.577 | 0.1347 | 111643.0 | 39500000 | 14500000000 | 5500000000000 | 0.4016 | 0.2477 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0020 | 0.0000 | 0.0124 | 0.0010 | 0.0615 | 0.0141 | 0.1154 | 0.0278 | 0.1391 | 0.0377 | 0.1708 | 0.0498 | 0.4976 | 0.8695 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0048 | 0.0006 | 0.0275 | 0.0103 | 0.0562 | 0.0177 | 0.0558 | 0.0168 | 0.0767 | 0.0242 | 0.7779 | 0.9305 | 0.0000 | 0.0057 | 0.0082 | 0.0341 | 0.0411 | 0.0625 | 0.0799 | 0.1591 | 0.1246 | 0.1932 | 0.1669 | 0.1648 | 0.1269 | 0.1193 | 0.1504 | 0.1307 | 0.3020 | 0.1307 | 0.0025 | 0.0038 | 0.0046 | 0.0302 | 0.0772 | 0.1234 | 0.1083 | 0.1318 | 0.5183 | 11 | 13 | 15 | 20 | 32 | 75 | 158 | 264 | 389 | 0.0486 | 32.17 | 5.262 | 0.4801 | 45355.6 | 21000000 | 11400000000 | 6870000000000 | 0.5030 | 0.1599 | 0.1206 | 0.0006 | 0.3330 | 0.0356 | 0.3146 | 0.2808 | 0.1079 | 0.2475 | 0.0769 | 0.1991 | 0.0321 | 0.1068 | 0.0115 | 0.0595 | 0.0023 | 0.0473 | 0.0011 | 0.0228 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0019 | 0.0009 | 0.0117 | 0.0095 | 0.0635 | 0.0521 | 0.0928 | 0.0937 | 0.0628 | 0.0577 | 0.1074 | 0.0968 | 0.6595 | 0.6891 | 0.0007 | 0.0007 | 0.0007 | 0.0015 | 0.0029 | 0.0020 | 0.0167 | 0.0162 | 0.0625 | 0.0729 | 0.1186 | 0.1226 | 0.0783 | 0.0896 | 0.1208 | 0.1300 | 0.5988 | 0.5646 | 0.0000 | 0.0002 | 0.0037 | 0.0165 | 0.0591 | 0.1021 | 0.0779 | 0.1118 | 0.6285 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 571 | 922 | 4617 | 8322 | 491.0 | 95.75 | 198.40 | 274.48 | 372 | 405 | 431 | 459 | 485 | 511 | 541 | 573 | 621 | 0.0908 | 756 | 1.217 | 121.30 | 48.70 | 1 | 0.0682 | 315 | 0.0006 | 68.44 | 7.576 | 0.1426 | 250279.0 | 132000000 | 72100000000 | 40600000000000 | 0.4178 | 0.2313 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0002 | 0.0112 | 0.0025 | 0.0586 | 0.0169 | 0.1189 | 0.0373 | 0.1287 | 0.0263 | 0.1587 | 0.0443 | 0.5217 | 0.8725 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0064 | 0.0011 | 0.0309 | 0.0133 | 0.0554 | 0.0279 | 0.0492 | 0.0168 | 0.0717 | 0.0251 | 0.7855 | 0.9157 | 0.0040 | 0.0000 | 0.0081 | 0.0000 | 0.0256 | 0.0000 | 0.0823 | 0.0000 | 0.1107 | 0.0000 | 0.1741 | 0.0000 | 0.1039 | 0.0000 | 0.1323 | 0.0000 | 0.3590 | 0.0000 | 0.0005 | 0.0023 | 0.0059 | 0.0244 | 0.0765 | 0.1199 | 0.0851 | 0.1231 | 0.5624 | 15 | 20 | 25 | 38 | 68 | 118 | 188 | 348 | 633 | 0.0340 | 31.16 | 5.359 | 0.5201 | 114691.0 | 92700000 | 87100000000 | 90400000000000 | 0.3987 | 0.2243 | 0.0214 | 0.0007 | 0.1193 | 0.0152 | 0.2370 | 0.0550 | 0.1330 | 0.0774 | 0.1361 | 0.1527 | 0.1055 | 0.2069 | 0.0826 | 0.1122 | 0.0841 | 0.1165 | 0.0810 | 0.2634 | 0.0004 | 0.0003 | 0.0029 | 0.0015 | 0.0022 | 0.0021 | 0.0122 | 0.0114 | 0.0561 | 0.0418 | 0.0820 | 0.0749 | 0.0557 | 0.0523 | 0.0805 | 0.0737 | 0.7080 | 0.7419 | 0.0005 | 0.0000 | 0.0014 | 0.0010 | 0.0056 | 0.0031 | 0.0118 | 0.0118 | 0.0592 | 0.0536 | 0.0870 | 0.1050 | 0.0602 | 0.0551 | 0.0827 | 0.0881 | 0.6916 | 0.6823 | 0.0008 | 0.0017 | 0.0033 | 0.0124 | 0.0541 | 0.0880 | 0.0570 | 0.0843 | 0.6985 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1139 | 881 | 6326 | 14317 | 189.9 | 47.31 | 165.02 | 129.26 | 138 | 151 | 161 | 171 | 182 | 193 | 206 | 224 | 252 | 0.0773 | 1106 | 1.024 | 100.80 | 38.29 | 1 | 0.0438 | 277 | 0.0012 | 42.09 | 7.012 | 0.1876 | 38280.7 | 8230000 | 1890000000 | 462000000000 | 0.4259 | 0.2291 | 0.0005 | 0.0000 | 0.0013 | 0.0000 | 0.0057 | 0.0000 | 0.0234 | 0.0019 | 0.0776 | 0.0210 | 0.1558 | 0.0447 | 0.1631 | 0.0445 | 0.1831 | 0.0635 | 0.3895 | 0.8244 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0000 | 0.0098 | 0.0003 | 0.0319 | 0.0121 | 0.0718 | 0.0241 | 0.0706 | 0.0168 | 0.0970 | 0.0254 | 0.7152 | 0.9213 | 0.0052 | 0.0064 | 0.0103 | 0.0107 | 0.0207 | 0.0258 | 0.0767 | 0.0794 | 0.1259 | 0.1803 | 0.1759 | 0.1674 | 0.1190 | 0.1180 | 0.1250 | 0.1545 | 0.3414 | 0.2575 | 0.0007 | 0.0055 | 0.0117 | 0.0371 | 0.0950 | 0.1273 | 0.1185 | 0.1383 | 0.4659 | 34 | 48 | 69 | 97 | 132 | 170 | 214 | 268 | 354 | 0.0028 | 59.79 | 6.896 | 0.2662 | 43937.1 | 15200000 | 6170000000 | 2820000000000 | 0.5199 | 0.1445 | 0.0243 | 0.0025 | 0.1004 | 0.0068 | 0.2160 | 0.0533 | 0.1831 | 0.1121 | 0.1711 | 0.1528 | 0.1263 | 0.1873 | 0.0814 | 0.1483 | 0.0675 | 0.1416 | 0.0300 | 0.1953 | 0.0008 | 0.0007 | 0.0008 | 0.0002 | 0.0040 | 0.0028 | 0.0205 | 0.0158 | 0.0656 | 0.0457 | 0.0960 | 0.0802 | 0.0795 | 0.0679 | 0.1224 | 0.0924 | 0.6103 | 0.6942 | 0.0013 | 0.0018 | 0.0055 | 0.0060 | 0.0103 | 0.0189 | 0.0352 | 0.0463 | 0.0967 | 0.1178 | 0.1415 | 0.1568 | 0.1118 | 0.1307 | 0.1417 | 0.1494 | 0.4561 | 0.3722 | 0.0007 | 0.0012 | 0.0066 | 0.0298 | 0.0752 | 0.1185 | 0.1015 | 0.1342 | 0.5323 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1163 | 914 | 2848 | 4080 | 128.2 | 26.29 | 72.09 | 52.48 | 98 | 106 | 112 | 118 | 124 | 131 | 140 | 151 | 166 | 0.1199 | 489 | 1.053 | 105.55 | 34.18 | 1 | 0.0952 | 271 | 0.0016 | 34.35 | 6.710 | 0.2008 | 17134.3 | 2390000 | 346000000 | 52000000000 | 0.4596 | 0.1985 | 0.0005 | 0.0000 | 0.0026 | 0.0000 | 0.0083 | 0.0011 | 0.0365 | 0.0033 | 0.0813 | 0.0228 | 0.1370 | 0.0538 | 0.1370 | 0.0435 | 0.1917 | 0.0748 | 0.4052 | 0.8007 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0021 | 0.0004 | 0.0153 | 0.0004 | 0.0425 | 0.0148 | 0.0689 | 0.0445 | 0.0669 | 0.0169 | 0.1102 | 0.0342 | 0.6929 | 0.8889 | 0.0060 | 0.0252 | 0.0099 | 0.0672 | 0.0298 | 0.0756 | 0.0736 | 0.2521 | 0.1650 | 0.2017 | 0.2107 | 0.1513 | 0.1233 | 0.0924 | 0.1551 | 0.1008 | 0.2266 | 0.0336 | 0.0031 | 0.0039 | 0.0164 | 0.0374 | 0.0997 | 0.1394 | 0.1012 | 0.1355 | 0.4634 | 25 | 34 | 43 | 51 | 59 | 69 | 81 | 99 | 131 | 0.0231 | 3.25 | 4.328 | 0.5781 | 7950.5 | 1300000 | 290000000 | 79400000000 | 0.5593 | 0.1262 | 0.0086 | 0.0015 | 0.0574 | 0.0068 | 0.1463 | 0.0181 | 0.1663 | 0.0556 | 0.1740 | 0.1171 | 0.1463 | 0.1679 | 0.1205 | 0.1445 | 0.1052 | 0.1723 | 0.0755 | 0.3163 | 0.0019 | 0.0011 | 0.0057 | 0.0032 | 0.0127 | 0.0081 | 0.0340 | 0.0218 | 0.0816 | 0.0567 | 0.1108 | 0.0820 | 0.1066 | 0.0753 | 0.1472 | 0.1137 | 0.4995 | 0.6383 | 0.0028 | 0.0063 | 0.0084 | 0.0063 | 0.0307 | 0.0378 | 0.0568 | 0.0908 | 0.1331 | 0.1311 | 0.1695 | 0.1702 | 0.1089 | 0.1059 | 0.1406 | 0.1248 | 0.3492 | 0.3266 | 0.0071 | 0.0065 | 0.0162 | 0.0518 | 0.0945 | 0.1579 | 0.1204 | 0.1379 | 0.4078 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1109 | 467 | 7728 | 10985 | 187.4 | 61.96 | 106.16 | 170.18 | 109 | 128 | 147 | 169 | 186 | 203 | 220 | 239 | 268 | 0.0861 | 946 | 1.180 | 100.90 | 29.02 | 3 | 0.0294 | 227 | 0.0011 | 27.43 | 7.104 | 0.2644 | 38959.5 | 8810000 | 2140000000 | 549000000000 | 0.4404 | 0.1893 | 0.0019 | 0.0005 | 0.0066 | 0.0013 | 0.0109 | 0.0023 | 0.0241 | 0.0084 | 0.0675 | 0.0240 | 0.0947 | 0.0473 | 0.0944 | 0.0455 | 0.1310 | 0.0624 | 0.5688 | 0.8083 | 0.0006 | 0.0003 | 0.0015 | 0.0009 | 0.0032 | 0.0012 | 0.0043 | 0.0039 | 0.0171 | 0.0115 | 0.0221 | 0.0195 | 0.0225 | 0.0169 | 0.0332 | 0.0232 | 0.8955 | 0.9226 | 0.0028 | 0.0045 | 0.0052 | 0.0034 | 0.0131 | 0.0101 | 0.0197 | 0.0515 | 0.0553 | 0.1074 | 0.0933 | 0.1398 | 0.0778 | 0.1040 | 0.1172 | 0.1275 | 0.6157 | 0.4519 | 0.0003 | 0.0005 | 0.0034 | 0.0120 | 0.0330 | 0.0494 | 0.0546 | 0.0738 | 0.7730 | 10 | 13 | 16 | 20 | 29 | 52 | 97 | 156 | 295 | 0.0735 | 19.46 | 4.540 | 0.5815 | 40229.5 | 25000000 | 19500000000 | 17300000000000 | 0.4726 | 0.1847 | 0.0486 | 0.0029 | 0.0972 | 0.0161 | 0.1627 | 0.0732 | 0.1333 | 0.0992 | 0.1345 | 0.1522 | 0.1390 | 0.1690 | 0.0949 | 0.1107 | 0.0836 | 0.1148 | 0.1062 | 0.2618 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0042 | 0.0027 | 0.0152 | 0.0126 | 0.0576 | 0.0567 | 0.0829 | 0.0680 | 0.0576 | 0.0508 | 0.0880 | 0.0841 | 0.6936 | 0.7242 | 0.0007 | 0.0009 | 0.0045 | 0.0047 | 0.0064 | 0.0108 | 0.0288 | 0.0284 | 0.0804 | 0.0814 | 0.0932 | 0.1063 | 0.0718 | 0.0689 | 0.1044 | 0.1029 | 0.6098 | 0.5958 | 0.0003 | 0.0019 | 0.0055 | 0.0183 | 0.0685 | 0.0985 | 0.0711 | 0.1046 | 0.6313 | |||
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 599 | 374 | 6551 | 17041 | 267.6 | 66.19 | 105.49 | 114.89 | 194 | 211 | 226 | 241 | 255 | 271 | 293 | 319 | 363 | 0.0596 | 1016 | 1.053 | 98.33 | 35.17 | 1 | 0.0400 | 262 | 0.0008 | 56.30 | 7.438 | 0.1617 | 75974.1 | 22900000 | 7350000000 | 2490000000000 | 0.4000 | 0.2484 | 0.0008 | 0.0000 | 0.0034 | 0.0003 | 0.0047 | 0.0005 | 0.0238 | 0.0032 | 0.0663 | 0.0219 | 0.1305 | 0.0441 | 0.1370 | 0.0413 | 0.1859 | 0.0657 | 0.4477 | 0.8230 | 0.0004 | 0.0000 | 0.0022 | 0.0000 | 0.0022 | 0.0000 | 0.0124 | 0.0008 | 0.0271 | 0.0139 | 0.0574 | 0.0225 | 0.0594 | 0.0169 | 0.0936 | 0.0300 | 0.7454 | 0.9159 | 0.0048 | 0.0079 | 0.0072 | 0.0099 | 0.0183 | 0.0217 | 0.0462 | 0.0791 | 0.0916 | 0.1462 | 0.1371 | 0.1798 | 0.1139 | 0.1146 | 0.1394 | 0.1462 | 0.4414 | 0.2945 | 0.0018 | 0.0029 | 0.0058 | 0.0282 | 0.0762 | 0.1181 | 0.0986 | 0.1203 | 0.5482 | 12 | 15 | 20 | 33 | 58 | 96 | 143 | 192 | 256 | 0.0374 | 9.37 | 5.007 | 0.5330 | 24326.7 | 7980000 | 3300000000 | 1610000000000 | 0.5431 | 0.1194 | 0.0353 | 0.0003 | 0.2286 | 0.0100 | 0.3382 | 0.1134 | 0.1429 | 0.1621 | 0.1127 | 0.2268 | 0.0793 | 0.2001 | 0.0390 | 0.1222 | 0.0157 | 0.0806 | 0.0082 | 0.0845 | 0.0001 | 0.0000 | 0.0003 | 0.0005 | 0.0014 | 0.0004 | 0.0096 | 0.0081 | 0.0557 | 0.0459 | 0.1000 | 0.0861 | 0.0671 | 0.0552 | 0.0956 | 0.0849 | 0.6703 | 0.7189 | 0.0002 | 0.0006 | 0.0016 | 0.0026 | 0.0019 | 0.0060 | 0.0157 | 0.0227 | 0.0714 | 0.0843 | 0.1314 | 0.1389 | 0.0812 | 0.0897 | 0.1127 | 0.1180 | 0.5839 | 0.5372 | 0.0002 | 0.0008 | 0.0031 | 0.0103 | 0.0642 | 0.1150 | 0.0771 | 0.1071 | 0.6223 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 715 | 284 | 4349 | 24088 | 89.5 | 13.78 | 5.43 | 2.07 | 73 | 77 | 80 | 84 | 87 | 91 | 97 | 103 | 109 | 0.0418 | 1008 | 0.588 | 324.65 | 84.85 | 1 | 0.2175 | 946 | 0.0394 | 0.86 | 3.496 | 0.6959 | 8200.8 | 769285 | 73900000 | 7250000000 | 0.4494 | 0.2031 | 0.0008 | 0.0000 | 0.0051 | 0.0000 | 0.0102 | 0.0007 | 0.0254 | 0.0044 | 0.0392 | 0.0120 | 0.0621 | 0.0294 | 0.0708 | 0.0204 | 0.1033 | 0.0328 | 0.6830 | 0.9003 | 0.0005 | 0.0000 | 0.0027 | 0.0000 | 0.0056 | 0.0007 | 0.0144 | 0.0037 | 0.0237 | 0.0115 | 0.0345 | 0.0283 | 0.0362 | 0.0170 | 0.0511 | 0.0255 | 0.8312 | 0.9133 | 0.0183 | 0.0800 | 0.0220 | 0.0800 | 0.0661 | 0.0000 | 0.0771 | 0.2400 | 0.0789 | 0.1600 | 0.0881 | 0.0400 | 0.0844 | 0.2800 | 0.1101 | 0.0400 | 0.4550 | 0.0800 | 0.0079 | 0.0173 | 0.0283 | 0.0336 | 0.0378 | 0.0420 | 0.0535 | 0.0991 | 0.6807 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.5147 | 0.30 | 0.895 | 0.8351 | 33.8 | 231.792 | 1719.99 | 13657.8 | 0.5085 | 0.1610 | 0.0301 | 0.0016 | 0.0914 | 0.0107 | 0.1790 | 0.0368 | 0.2367 | 0.0927 | 0.2312 | 0.1792 | 0.1506 | 0.2518 | 0.0667 | 0.2459 | 0.0126 | 0.1425 | 0.0017 | 0.0387 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0019 | 0.0004 | 0.0124 | 0.0041 | 0.0401 | 0.0133 | 0.1042 | 0.0327 | 0.2310 | 0.0785 | 0.3474 | 0.2650 | 0.2627 | 0.6059 | 0.0142 | 0.0719 | 0.0704 | 0.1807 | 0.1551 | 0.2535 | 0.2061 | 0.2209 | 0.2091 | 0.1486 | 0.1568 | 0.0748 | 0.1088 | 0.0355 | 0.0596 | 0.0115 | 0.0198 | 0.0026 | 0.0004 | 0.0054 | 0.0302 | 0.0848 | 0.1735 | 0.2508 | 0.2509 | 0.1550 | 0.0492 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 116 | 222 | 4981 | 10103 | 405.1 | 89.96 | 157.47 | 168.79 | 303 | 330 | 351 | 372 | 393 | 414 | 437 | 472 | 529 | 0.0726 | 733 | 0.947 | 146.69 | 44.27 | 1 | 0.0765 | 381 | 0.0010 | 46.38 | 7.194 | 0.1694 | 172181.0 | 76900000 | 36100000000 | 17800000000000 | 0.4170 | 0.2320 | 0.0009 | 0.0000 | 0.0006 | 0.0002 | 0.0061 | 0.0002 | 0.0134 | 0.0030 | 0.0510 | 0.0201 | 0.1197 | 0.0402 | 0.1212 | 0.0369 | 0.1555 | 0.0520 | 0.5316 | 0.8474 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0051 | 0.0006 | 0.0261 | 0.0128 | 0.0622 | 0.0261 | 0.0566 | 0.0170 | 0.0832 | 0.0251 | 0.7642 | 0.9184 | 0.0000 | 0.0065 | 0.0095 | 0.0032 | 0.0202 | 0.0356 | 0.0606 | 0.0874 | 0.1021 | 0.1392 | 0.1164 | 0.1359 | 0.1152 | 0.1456 | 0.1318 | 0.1230 | 0.4442 | 0.3236 | 0.0000 | 0.0045 | 0.0050 | 0.0389 | 0.0811 | 0.1241 | 0.0933 | 0.1295 | 0.5236 | 12 | 18 | 27 | 51 | 92 | 149 | 210 | 289 | 400 | 0.0190 | 31.43 | 5.829 | 0.4202 | 53285.1 | 24200000 | 13200000000 | 8210000000000 | 0.4079 | 0.2092 | 0.0230 | 0.0010 | 0.1168 | 0.0114 | 0.2061 | 0.0547 | 0.1914 | 0.1099 | 0.1582 | 0.1932 | 0.1509 | 0.2018 | 0.0846 | 0.1366 | 0.0414 | 0.1376 | 0.0276 | 0.1537 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0011 | 0.0012 | 0.0119 | 0.0086 | 0.0452 | 0.0426 | 0.0796 | 0.0616 | 0.0598 | 0.0476 | 0.0830 | 0.0710 | 0.7189 | 0.7671 | 0.0003 | 0.0007 | 0.0009 | 0.0031 | 0.0060 | 0.0090 | 0.0199 | 0.0193 | 0.0673 | 0.0835 | 0.1185 | 0.1308 | 0.0798 | 0.0860 | 0.1146 | 0.1267 | 0.5929 | 0.5409 | 0.0000 | 0.0010 | 0.0049 | 0.0194 | 0.0537 | 0.0980 | 0.0668 | 0.1011 | 0.6551 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1274 | 376 | 2281 | 2786 | 112.4 | 25.36 | 148.51 | 132.43 | 87 | 92 | 97 | 102 | 107 | 112 | 119 | 128 | 147 | 0.1637 | 456 | 1.143 | 80.71 | 26.48 | 1 | 0.0886 | 202 | 0.0048 | 13.65 | 5.717 | 0.3134 | 13272.8 | 1660000 | 220000000 | 31200000000 | 0.3671 | 0.2788 | 0.0013 | 0.0000 | 0.0019 | 0.0000 | 0.0126 | 0.0000 | 0.0265 | 0.0028 | 0.0670 | 0.0317 | 0.1062 | 0.0602 | 0.1207 | 0.0417 | 0.1903 | 0.0677 | 0.4735 | 0.7958 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0083 | 0.0000 | 0.0129 | 0.0013 | 0.0326 | 0.0193 | 0.0625 | 0.0408 | 0.0641 | 0.0171 | 0.1013 | 0.0289 | 0.7163 | 0.8926 | 0.0085 | 0.0000 | 0.0170 | 0.0176 | 0.0255 | 0.0353 | 0.0595 | 0.1000 | 0.1360 | 0.1294 | 0.1105 | 0.1471 | 0.1133 | 0.1647 | 0.1586 | 0.1353 | 0.3711 | 0.2706 | 0.0044 | 0.0065 | 0.0153 | 0.0513 | 0.0938 | 0.1134 | 0.1080 | 0.1363 | 0.4711 | 14 | 25 | 51 | 80 | 114 | 151 | 191 | 253 | 347 | 0.0074 | 29.86 | 6.106 | 0.3653 | 39586.9 | 13600000 | 5450000000 | 2400000000000 | 0.4919 | 0.1616 | 0.0228 | 0.0059 | 0.0752 | 0.0164 | 0.1686 | 0.0457 | 0.1595 | 0.0726 | 0.1800 | 0.1581 | 0.1458 | 0.1546 | 0.0911 | 0.1347 | 0.0752 | 0.1475 | 0.0820 | 0.2646 | 0.0015 | 0.0012 | 0.0044 | 0.0019 | 0.0059 | 0.0062 | 0.0236 | 0.0137 | 0.0707 | 0.0616 | 0.1216 | 0.1082 | 0.0892 | 0.0721 | 0.1054 | 0.0927 | 0.5777 | 0.6424 | 0.0033 | 0.0027 | 0.0044 | 0.0080 | 0.0142 | 0.0159 | 0.0381 | 0.0491 | 0.0817 | 0.1048 | 0.1569 | 0.1605 | 0.1122 | 0.1061 | 0.1100 | 0.1194 | 0.4793 | 0.4337 | 0.0009 | 0.0062 | 0.0133 | 0.0318 | 0.0681 | 0.1388 | 0.1149 | 0.1114 | 0.5146 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 959 | 713 | 6139 | 10848 | 256.2 | 53.54 | 207.18 | 194.13 | 190 | 210 | 225 | 238 | 252 | 266 | 283 | 302 | 326 | 0.0678 | 736 | 1.177 | 102.18 | 37.66 | 1 | 0.0415 | 255 | 0.0008 | 47.93 | 7.299 | 0.1591 | 68517.0 | 19100000 | 5540000000 | 1670000000000 | 0.4834 | 0.1799 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0032 | 0.0003 | 0.0156 | 0.0014 | 0.0740 | 0.0133 | 0.1454 | 0.0377 | 0.1504 | 0.0343 | 0.1835 | 0.0591 | 0.4267 | 0.8538 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0016 | 0.0002 | 0.0059 | 0.0012 | 0.0355 | 0.0092 | 0.0646 | 0.0250 | 0.0616 | 0.0171 | 0.0826 | 0.0290 | 0.7478 | 0.9183 | 0.0067 | 0.0235 | 0.0114 | 0.0141 | 0.0352 | 0.0469 | 0.0856 | 0.1643 | 0.1369 | 0.1925 | 0.1835 | 0.2207 | 0.1274 | 0.0845 | 0.1340 | 0.0986 | 0.2795 | 0.1549 | 0.0024 | 0.0041 | 0.0093 | 0.0368 | 0.0764 | 0.1195 | 0.1012 | 0.1326 | 0.5176 | 19 | 34 | 61 | 103 | 155 | 210 | 274 | 353 | 472 | 0.0078 | 34.55 | 6.449 | 0.3311 | 80606.7 | 42400000 | 27300000000 | 20400000000000 | 0.4122 | 0.2269 | 0.0375 | 0.0010 | 0.1827 | 0.0076 | 0.2438 | 0.0851 | 0.1774 | 0.1506 | 0.1360 | 0.1962 | 0.1064 | 0.2035 | 0.0572 | 0.1157 | 0.0420 | 0.0994 | 0.0171 | 0.1407 | 0.0008 | 0.0002 | 0.0010 | 0.0012 | 0.0031 | 0.0027 | 0.0179 | 0.0119 | 0.0702 | 0.0586 | 0.1159 | 0.1040 | 0.0844 | 0.0695 | 0.1125 | 0.0949 | 0.5943 | 0.6571 | 0.0016 | 0.0020 | 0.0038 | 0.0020 | 0.0071 | 0.0076 | 0.0245 | 0.0311 | 0.0919 | 0.0967 | 0.1321 | 0.1652 | 0.1025 | 0.1119 | 0.1394 | 0.1317 | 0.4971 | 0.4518 | 0.0016 | 0.0016 | 0.0043 | 0.0200 | 0.0832 | 0.1402 | 0.0836 | 0.1216 | 0.5440 | |
BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 999 | 759 | 7014 | 22115 | 261.5 | 51.41 | 152.85 | 246.06 | 199 | 217 | 231 | 244 | 257 | 271 | 286 | 305 | 332 | 0.0572 | 1264 | 0.703 | 157.81 | 44.60 | 2 | 0.0720 | 505 | 0.0008 | 54.08 | 7.368 | 0.1589 | 71002.4 | 20000000 | 5820000000 | 1750000000000 | 0.4542 | 0.2013 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0198 | 0.0018 | 0.0614 | 0.0168 | 0.1165 | 0.0363 | 0.1431 | 0.0312 | 0.1561 | 0.0529 | 0.4986 | 0.8610 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0065 | 0.0007 | 0.0317 | 0.0127 | 0.0548 | 0.0245 | 0.0634 | 0.0171 | 0.0806 | 0.0298 | 0.7622 | 0.9151 | 0.0035 | 0.0142 | 0.0132 | 0.0474 | 0.0307 | 0.0664 | 0.0729 | 0.1232 | 0.1484 | 0.2133 | 0.1756 | 0.1706 | 0.1089 | 0.1611 | 0.1528 | 0.1137 | 0.2941 | 0.0900 | 0.0009 | 0.0021 | 0.0081 | 0.0332 | 0.0865 | 0.1293 | 0.1164 | 0.1320 | 0.4914 | 9 | 11 | 12 | 14 | 18 | 37 | 127 | 301 | 523 | 0.1005 | 52.42 | 4.809 | 0.5431 | 83904.9 | 63400000 | 57600000000 | 60200000000000 | 0.4909 | 0.1549 | 0.1011 | 0.0081 | 0.3100 | 0.0501 | 0.3478 | 0.2536 | 0.1133 | 0.2036 | 0.0800 | 0.1659 | 0.0233 | 0.1438 | 0.0122 | 0.0845 | 0.0067 | 0.0549 | 0.0056 | 0.0355 | 0.0001 | 0.0004 | 0.0009 | 0.0006 | 0.0022 | 0.0018 | 0.0097 | 0.0091 | 0.0460 | 0.0426 | 0.0824 | 0.0794 | 0.0515 | 0.0480 | 0.0790 | 0.0681 | 0.7281 | 0.7501 | 0.0000 | 0.0007 | 0.0015 | 0.0024 | 0.0028 | 0.0041 | 0.0143 | 0.0111 | 0.0528 | 0.0560 | 0.0945 | 0.1016 | 0.0625 | 0.0621 | 0.0883 | 0.0970 | 0.6834 | 0.6651 | 0.0003 | 0.0006 | 0.0019 | 0.0083 | 0.0525 | 0.0906 | 0.0541 | 0.0823 | 0.7093 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 226 | 604 | 4693 | 21436 | 383.8 | 76.01 | 185.02 | 221.64 | 284 | 313 | 337 | 360 | 381 | 402 | 425 | 454 | 486 | 0.0416 | 891 | 1.052 | 130.17 | 34.01 | 1 | 0.0641 | 301 | 0.0008 | 47.52 | 7.327 | 0.1592 | 153105.0 | 63300000 | 27000000000 | 11900000000000 | 0.3995 | 0.2470 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0023 | 0.0002 | 0.0165 | 0.0017 | 0.0621 | 0.0177 | 0.1229 | 0.0293 | 0.1371 | 0.0275 | 0.1688 | 0.0446 | 0.4889 | 0.8790 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0073 | 0.0015 | 0.0275 | 0.0148 | 0.0536 | 0.0238 | 0.0573 | 0.0171 | 0.0744 | 0.0278 | 0.7785 | 0.9150 | 0.0000 | 0.0000 | 0.0120 | 0.0000 | 0.0156 | 0.0000 | 0.0648 | 0.0000 | 0.1212 | 0.0000 | 0.1633 | 0.0000 | 0.1357 | 0.0000 | 0.1465 | 0.0000 | 0.3409 | 0.0000 | 0.0000 | 0.0009 | 0.0069 | 0.0221 | 0.0711 | 0.1111 | 0.0954 | 0.1176 | 0.5748 | 15 | 18 | 24 | 44 | 80 | 141 | 230 | 343 | 529 | 0.0288 | 19.62 | 5.529 | 0.4998 | 83352.2 | 50500000 | 35500000000 | 27500000000000 | 0.4199 | 0.2507 | 0.0207 | 0.0005 | 0.0995 | 0.0062 | 0.2392 | 0.0328 | 0.2041 | 0.0859 | 0.1593 | 0.1798 | 0.1282 | 0.2251 | 0.0610 | 0.1479 | 0.0518 | 0.1262 | 0.0362 | 0.1956 | 0.0004 | 0.0000 | 0.0006 | 0.0003 | 0.0016 | 0.0010 | 0.0080 | 0.0073 | 0.0421 | 0.0351 | 0.0732 | 0.0620 | 0.0459 | 0.0433 | 0.0727 | 0.0653 | 0.7556 | 0.7856 | 0.0000 | 0.0003 | 0.0009 | 0.0012 | 0.0020 | 0.0024 | 0.0131 | 0.0137 | 0.0524 | 0.0608 | 0.0851 | 0.0996 | 0.0622 | 0.0649 | 0.0907 | 0.0941 | 0.6935 | 0.6629 | 0.0001 | 0.0005 | 0.0023 | 0.0104 | 0.0496 | 0.0769 | 0.0547 | 0.0770 | 0.7284 |