High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 767 | 375 | | 10994 | 36702 | 317.2 | 66.33 | 88.78 | 117.60 | 238 | 259 | 276 | 292 | 309 | 327 | 346 | 373 | 410 | 0.0385 | 1412 | 0.777 | 113.02 | 23.02 | 1 | 0.0226 | 249 | 0.0006 | 70.27 | 7.726 | 0.1479 | 104984.0 | 36300000 | 13000000000 | 4880000000000 | 0.4228 | 0.2250 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0001 | 0.0125 | 0.0008 | 0.0612 | 0.0134 | 0.1259 | 0.0305 | 0.1295 | 0.0324 | 0.1666 | 0.0567 | 0.4994 | 0.8660 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0062 | 0.0003 | 0.0265 | 0.0088 | 0.0510 | 0.0177 | 0.0541 | 0.0124 | 0.0766 | 0.0239 | 0.7828 | 0.9370 | 0.0031 | 0.0102 | 0.0078 | 0.0225 | 0.0225 | 0.0758 | 0.0628 | 0.1250 | 0.1313 | 0.1557 | 0.1763 | 0.1475 | 0.1104 | 0.1025 | 0.1423 | 0.1270 | 0.3433 | 0.2336 | 0.0010 | 0.0030 | 0.0062 | 0.0294 | 0.0726 | 0.1184 | 0.1031 | 0.1345 | 0.5318 | 10 | 12 | 14 | 19 | 32 | 55 | 97 | 156 | 255 | 0.0788 | 13.52 | 4.639 | 0.5538 | 21712.5 | 8010000 | 3800000000 | 2180000000000 | 0.4103 | 0.2154 | 0.0637 | 0.0009 | 0.2390 | 0.0098 | 0.3525 | 0.1068 | 0.1643 | 0.1924 | 0.0959 | 0.2534 | 0.0480 | 0.2004 | 0.0216 | 0.1040 | 0.0113 | 0.0742 | 0.0037 | 0.0580 | 0.0002 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0012 | 0.0109 | 0.0097 | 0.0639 | 0.0507 | 0.0964 | 0.0843 | 0.0715 | 0.0616 | 0.1087 | 0.0931 | 0.6473 | 0.6989 | 0.0002 | 0.0004 | 0.0011 | 0.0016 | 0.0034 | 0.0043 | 0.0175 | 0.0189 | 0.0814 | 0.0927 | 0.1222 | 0.1338 | 0.0853 | 0.0887 | 0.1273 | 0.1253 | 0.5616 | 0.5343 | 0.0001 | 0.0004 | 0.0016 | 0.0110 | 0.0724 | 0.1147 | 0.0774 | 0.1169 | 0.6055 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 465 | 643 | | 8720 | 12380 | 327.7 | 56.71 | 178.47 | 263.33 | 253 | 288 | 306 | 320 | 333 | 346 | 358 | 371 | 394 | 0.0826 | 1023 | 1.053 | 189.34 | 55.01 | 1 | 0.0515 | 449 | 0.0016 | 19.71 | 6.739 | 0.2552 | 110617.0 | 38300000 | 13500000000 | 4860000000000 | 0.4132 | 0.2316 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0010 | 0.0001 | 0.0059 | 0.0010 | 0.0246 | 0.0101 | 0.0541 | 0.0199 | 0.0557 | 0.0130 | 0.0950 | 0.0226 | 0.7636 | 0.9332 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0001 | 0.0030 | 0.0009 | 0.0126 | 0.0096 | 0.0228 | 0.0178 | 0.0228 | 0.0096 | 0.0370 | 0.0162 | 0.9017 | 0.9456 | 0.0114 | 0.0000 | 0.0227 | 0.0000 | 0.0272 | 0.0000 | 0.0681 | 0.0000 | 0.0988 | 0.0000 | 0.1703 | 0.0000 | 0.1067 | 0.0000 | 0.1226 | 0.0000 | 0.3723 | 0.0000 | 0.0008 | 0.0019 | 0.0071 | 0.0173 | 0.0483 | 0.0854 | 0.0861 | 0.1201 | 0.6330 | 18 | 25 | 36 | 52 | 72 | 98 | 148 | 262 | 503 | 0.0250 | 35.86 | 5.284 | 0.5431 | 101188.0 | 92200000 | 104000000000 | 133000000000000 | 0.5504 | 0.1103 | 0.0118 | 0.0028 | 0.0634 | 0.0052 | 0.1160 | 0.0282 | 0.1461 | 0.0612 | 0.1912 | 0.1266 | 0.1751 | 0.1507 | 0.1224 | 0.1351 | 0.0988 | 0.1573 | 0.0752 | 0.3329 | 0.0005 | 0.0002 | 0.0003 | 0.0011 | 0.0024 | 0.0023 | 0.0079 | 0.0094 | 0.0482 | 0.0428 | 0.0854 | 0.0656 | 0.0514 | 0.0563 | 0.0801 | 0.0808 | 0.7238 | 0.7415 | 0.0000 | 0.0000 | 0.0021 | 0.0008 | 0.0042 | 0.0035 | 0.0101 | 0.0097 | 0.0538 | 0.0635 | 0.0894 | 0.0884 | 0.0594 | 0.0666 | 0.0876 | 0.0970 | 0.6934 | 0.6706 | 0.0000 | 0.0003 | 0.0031 | 0.0089 | 0.0520 | 0.0851 | 0.0560 | 0.0875 | 0.7072 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1211 | 757 | | 6987 | 17413 | 330.1 | 42.49 | 131.75 | 174.14 | 277 | 295 | 309 | 320 | 331 | 341 | 352 | 366 | 384 | 0.0637 | 1110 | 0.875 | 72.84 | 16.16 | 1 | 0.0238 | 166 | 0.0022 | 16.55 | 6.447 | 0.2611 | 110777.0 | 37800000 | 13100000000 | 4580000000000 | 0.4400 | 0.2087 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0062 | 0.0000 | 0.0213 | 0.0109 | 0.0321 | 0.0178 | 0.0485 | 0.0100 | 0.0745 | 0.0186 | 0.8160 | 0.9427 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0000 | 0.0128 | 0.0109 | 0.0169 | 0.0178 | 0.0198 | 0.0095 | 0.0305 | 0.0166 | 0.9167 | 0.9453 | 0.0122 | 0.0000 | 0.0389 | 1.0000 | 0.0681 | 0.0000 | 0.1387 | 0.0000 | 0.1363 | 0.0000 | 0.1533 | 0.0000 | 0.1314 | 0.0000 | 0.1265 | 0.0000 | 0.1946 | 0.0000 | 0.0017 | 0.0047 | 0.0111 | 0.0255 | 0.0505 | 0.0813 | 0.0921 | 0.1160 | 0.6171 | 11 | 14 | 16 | 20 | 45 | 85 | 148 | 242 | 391 | 0.0761 | 18.56 | 4.883 | 0.5466 | 47679.7 | 24000000 | 14300000000 | 9510000000000 | 0.5710 | 0.1004 | 0.0354 | 0.0022 | 0.1286 | 0.0170 | 0.1973 | 0.0815 | 0.1517 | 0.1130 | 0.1402 | 0.1735 | 0.1156 | 0.1590 | 0.0860 | 0.1101 | 0.0744 | 0.1093 | 0.0708 | 0.2342 | 0.0002 | 0.0003 | 0.0005 | 0.0013 | 0.0017 | 0.0015 | 0.0103 | 0.0083 | 0.0444 | 0.0392 | 0.0713 | 0.0616 | 0.0547 | 0.0447 | 0.0799 | 0.0686 | 0.7370 | 0.7746 | 0.0002 | 0.0007 | 0.0022 | 0.0016 | 0.0044 | 0.0034 | 0.0156 | 0.0158 | 0.0577 | 0.0657 | 0.0944 | 0.1062 | 0.0716 | 0.0725 | 0.0954 | 0.1069 | 0.6586 | 0.6274 | 0.0004 | 0.0009 | 0.0034 | 0.0130 | 0.0497 | 0.0852 | 0.0639 | 0.0887 | 0.6949 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 454 | 777 | | 7409 | 17484 | 322.3 | 67.54 | 205.37 | 234.69 | 243 | 264 | 279 | 296 | 313 | 331 | 353 | 381 | 419 | 0.0565 | 988 | 1.214 | 100.09 | 46.32 | 1 | 0.0378 | 280 | 0.0005 | 88.54 | 7.749 | 0.1264 | 108444.0 | 38100000 | 13900000000 | 5270000000000 | 0.4118 | 0.2358 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0027 | 0.0000 | 0.0126 | 0.0013 | 0.0653 | 0.0133 | 0.1407 | 0.0324 | 0.1465 | 0.0319 | 0.1766 | 0.0542 | 0.4551 | 0.8669 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0040 | 0.0001 | 0.0306 | 0.0082 | 0.0657 | 0.0178 | 0.0679 | 0.0118 | 0.0977 | 0.0245 | 0.7329 | 0.9376 | 0.0029 | 0.0057 | 0.0029 | 0.0172 | 0.0155 | 0.0602 | 0.0472 | 0.0888 | 0.1282 | 0.1977 | 0.1643 | 0.1748 | 0.1157 | 0.1175 | 0.1400 | 0.1547 | 0.3832 | 0.1834 | 0.0024 | 0.0027 | 0.0054 | 0.0338 | 0.0764 | 0.1255 | 0.0940 | 0.1234 | 0.5364 | 11 | 14 | 17 | 31 | 88 | 192 | 303 | 420 | 566 | 0.0364 | 50.81 | 5.936 | 0.4194 | 97252.5 | 57300000 | 38200000000 | 27900000000000 | 0.4410 | 0.1792 | 0.0679 | 0.0012 | 0.2334 | 0.0148 | 0.3166 | 0.1561 | 0.1663 | 0.2149 | 0.0900 | 0.2129 | 0.0748 | 0.1752 | 0.0282 | 0.0907 | 0.0175 | 0.0767 | 0.0053 | 0.0576 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0013 | 0.0006 | 0.0070 | 0.0062 | 0.0449 | 0.0360 | 0.0791 | 0.0719 | 0.0574 | 0.0536 | 0.0936 | 0.0726 | 0.7161 | 0.7591 | 0.0000 | 0.0007 | 0.0007 | 0.0016 | 0.0023 | 0.0042 | 0.0126 | 0.0140 | 0.0555 | 0.0663 | 0.0963 | 0.1117 | 0.0864 | 0.0871 | 0.1164 | 0.1189 | 0.6299 | 0.5955 | 0.0003 | 0.0013 | 0.0012 | 0.0113 | 0.0518 | 0.0818 | 0.0742 | 0.1052 | 0.6728 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 980 | 154 | | 9107 | 15265 | 478.7 | 85.92 | 198.56 | 276.33 | 358 | 401 | 437 | 463 | 485 | 506 | 527 | 552 | 588 | 0.0735 | 1122 | 0.982 | 84.40 | 29.43 | 4 | 0.0254 | 231 | 0.0010 | 22.23 | 7.221 | 0.2396 | 236580.0 | 120000000 | 62600000000 | 33300000000000 | 0.4434 | 0.2060 | 0.0008 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0001 | 0.0113 | 0.0006 | 0.0270 | 0.0119 | 0.0415 | 0.0194 | 0.0463 | 0.0139 | 0.0694 | 0.0222 | 0.7980 | 0.9319 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0012 | 0.0000 | 0.0040 | 0.0006 | 0.0131 | 0.0117 | 0.0209 | 0.0179 | 0.0208 | 0.0114 | 0.0297 | 0.0180 | 0.9101 | 0.9405 | 0.0083 | 0.0294 | 0.0173 | 0.0588 | 0.0273 | 0.0882 | 0.0380 | 0.2059 | 0.0512 | 0.2353 | 0.0760 | 0.1471 | 0.0950 | 0.1471 | 0.1230 | 0.0588 | 0.5640 | 0.0294 | 0.0010 | 0.0031 | 0.0072 | 0.0149 | 0.0256 | 0.0345 | 0.0450 | 0.0565 | 0.8122 | 11 | 14 | 19 | 34 | 73 | 133 | 224 | 349 | 565 | 0.0491 | 47.73 | 5.568 | 0.4783 | 115779.0 | 101000000 | 112000000000 | 147000000000000 | 0.3844 | 0.2395 | 0.0410 | 0.0015 | 0.1640 | 0.0173 | 0.2243 | 0.0857 | 0.1640 | 0.1357 | 0.1446 | 0.1765 | 0.1106 | 0.1922 | 0.0789 | 0.1361 | 0.0472 | 0.1023 | 0.0255 | 0.1526 | 0.0004 | 0.0003 | 0.0011 | 0.0014 | 0.0023 | 0.0048 | 0.0151 | 0.0114 | 0.0519 | 0.0457 | 0.0774 | 0.0628 | 0.0614 | 0.0517 | 0.0854 | 0.0750 | 0.7052 | 0.7469 | 0.0002 | 0.0005 | 0.0018 | 0.0031 | 0.0067 | 0.0089 | 0.0220 | 0.0270 | 0.0687 | 0.0786 | 0.1061 | 0.1226 | 0.0859 | 0.0881 | 0.1079 | 0.1098 | 0.6006 | 0.5613 | 0.0004 | 0.0012 | 0.0052 | 0.0181 | 0.0596 | 0.0890 | 0.0721 | 0.1031 | 0.6512 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1060 | 148 | | 9173 | 22344 | 294.9 | 54.87 | 142.27 | 167.42 | 227 | 246 | 262 | 276 | 290 | 304 | 321 | 343 | 371 | 0.0689 | 1540 | 0.872 | 128.71 | 44.38 | 1 | 0.0395 | 362 | 0.0007 | 53.70 | 7.461 | 0.1589 | 89976.7 | 28400000 | 9240000000 | 3100000000000 | 0.4189 | 0.2273 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0039 | 0.0000 | 0.0119 | 0.0010 | 0.0544 | 0.0105 | 0.1011 | 0.0239 | 0.1296 | 0.0218 | 0.1648 | 0.0345 | 0.5330 | 0.9084 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0059 | 0.0002 | 0.0246 | 0.0088 | 0.0420 | 0.0180 | 0.0587 | 0.0104 | 0.0811 | 0.0154 | 0.7860 | 0.9472 | 0.0035 | 0.0359 | 0.0110 | 0.0256 | 0.0311 | 0.0769 | 0.0876 | 0.1487 | 0.1090 | 0.1436 | 0.1739 | 0.1641 | 0.1256 | 0.1128 | 0.1387 | 0.1231 | 0.3195 | 0.1692 | 0.0012 | 0.0047 | 0.0077 | 0.0323 | 0.0798 | 0.1131 | 0.0949 | 0.1254 | 0.5411 | 14 | 17 | 22 | 39 | 72 | 114 | 176 | 260 | 379 | 0.0282 | 29.29 | 5.688 | 0.4480 | 48267.7 | 23800000 | 15100000000 | 12000000000000 | 0.5526 | 0.1273 | 0.0495 | 0.0023 | 0.1676 | 0.0182 | 0.2382 | 0.0872 | 0.1820 | 0.1262 | 0.1201 | 0.1819 | 0.1042 | 0.1777 | 0.0735 | 0.1315 | 0.0360 | 0.1131 | 0.0288 | 0.1618 | 0.0010 | 0.0004 | 0.0013 | 0.0008 | 0.0025 | 0.0027 | 0.0122 | 0.0114 | 0.0574 | 0.0459 | 0.1001 | 0.0810 | 0.0689 | 0.0643 | 0.0971 | 0.0872 | 0.6595 | 0.7063 | 0.0003 | 0.0003 | 0.0007 | 0.0013 | 0.0044 | 0.0053 | 0.0173 | 0.0217 | 0.0820 | 0.0881 | 0.1194 | 0.1360 | 0.0834 | 0.0891 | 0.1164 | 0.1154 | 0.5761 | 0.5428 | 0.0005 | 0.0013 | 0.0029 | 0.0153 | 0.0705 | 0.1085 | 0.0767 | 0.1091 | 0.6152 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1162 | 577 | | 13856 | 32218 | 412.2 | 88.94 | 164.83 | 232.07 | 304 | 336 | 360 | 380 | 402 | 425 | 452 | 487 | 537 | 0.0416 | 1339 | 1.120 | 120.08 | 40.36 | 1 | 0.0211 | 292 | 0.0008 | 47.91 | 7.432 | 0.1705 | 177845.0 | 80200000 | 37700000000 | 18400000000000 | 0.4301 | 0.2191 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0005 | 0.0112 | 0.0023 | 0.0595 | 0.0147 | 0.1409 | 0.0309 | 0.1350 | 0.0320 | 0.1666 | 0.0506 | 0.4830 | 0.8691 | 0.0002 | 0.0000 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0045 | 0.0001 | 0.0264 | 0.0081 | 0.0665 | 0.0180 | 0.0589 | 0.0144 | 0.0831 | 0.0249 | 0.7596 | 0.9345 | 0.0043 | 0.0042 | 0.0036 | 0.0198 | 0.0213 | 0.0353 | 0.0588 | 0.0791 | 0.1113 | 0.1638 | 0.1552 | 0.1751 | 0.0991 | 0.1455 | 0.1204 | 0.1780 | 0.4260 | 0.1992 | 0.0009 | 0.0044 | 0.0096 | 0.0313 | 0.0768 | 0.1126 | 0.0944 | 0.1160 | 0.5540 | 7 | 9 | 11 | 18 | 43 | 99 | 192 | 328 | 498 | 0.0842 | 39.05 | 5.161 | 0.4769 | 81023.3 | 55900000 | 47700000000 | 47900000000000 | 0.4243 | 0.2283 | 0.1052 | 0.0021 | 0.2776 | 0.0324 | 0.3170 | 0.2034 | 0.1311 | 0.2094 | 0.0802 | 0.1990 | 0.0495 | 0.1459 | 0.0226 | 0.0876 | 0.0101 | 0.0631 | 0.0067 | 0.0571 | 0.0001 | 0.0001 | 0.0002 | 0.0002 | 0.0022 | 0.0012 | 0.0101 | 0.0092 | 0.0575 | 0.0513 | 0.1002 | 0.0842 | 0.0707 | 0.0637 | 0.1083 | 0.0944 | 0.6508 | 0.6958 | 0.0003 | 0.0007 | 0.0013 | 0.0009 | 0.0029 | 0.0034 | 0.0145 | 0.0165 | 0.0744 | 0.0808 | 0.1140 | 0.1269 | 0.0875 | 0.0901 | 0.1225 | 0.1277 | 0.5827 | 0.5529 | 0.0002 | 0.0008 | 0.0020 | 0.0126 | 0.0667 | 0.1066 | 0.0805 | 0.1167 | 0.6140 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 425 | 155 | | 10526 | 21020 | 318.4 | 61.96 | 206.32 | 250.19 | 242 | 266 | 284 | 299 | 314 | 330 | 347 | 369 | 404 | 0.0516 | 1084 | 1.093 | 105.19 | 36.12 | 1 | 0.0249 | 262 | 0.0006 | 81.62 | 7.746 | 0.1363 | 105224.0 | 36000000 | 12800000000 | 4660000000000 | 0.4431 | 0.2108 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0026 | 0.0000 | 0.0134 | 0.0015 | 0.0534 | 0.0127 | 0.1190 | 0.0291 | 0.1293 | 0.0329 | 0.1742 | 0.0536 | 0.5079 | 0.8701 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0007 | 0.0233 | 0.0087 | 0.0553 | 0.0181 | 0.0559 | 0.0145 | 0.0879 | 0.0257 | 0.7716 | 0.9324 | 0.0047 | 0.0280 | 0.0142 | 0.0592 | 0.0272 | 0.0592 | 0.0781 | 0.1526 | 0.1230 | 0.2087 | 0.1715 | 0.2150 | 0.1212 | 0.1277 | 0.1467 | 0.0779 | 0.3134 | 0.0717 | 0.0012 | 0.0020 | 0.0075 | 0.0315 | 0.0817 | 0.1365 | 0.1121 | 0.1303 | 0.4971 | 16 | 20 | 26 | 45 | 90 | 165 | 257 | 379 | 569 | 0.0265 | 51.36 | 6.104 | 0.4177 | 105162.0 | 74300000 | 63500000000 | 62100000000000 | 0.4677 | 0.1545 | 0.0348 | 0.0018 | 0.1515 | 0.0098 | 0.2413 | 0.0665 | 0.1600 | 0.1355 | 0.1658 | 0.1909 | 0.1109 | 0.1899 | 0.0702 | 0.1368 | 0.0428 | 0.1209 | 0.0227 | 0.1479 | 0.0001 | 0.0002 | 0.0006 | 0.0006 | 0.0021 | 0.0007 | 0.0075 | 0.0067 | 0.0513 | 0.0425 | 0.0842 | 0.0699 | 0.0615 | 0.0534 | 0.0927 | 0.0778 | 0.7001 | 0.7481 | 0.0000 | 0.0002 | 0.0017 | 0.0024 | 0.0040 | 0.0065 | 0.0161 | 0.0168 | 0.0672 | 0.0746 | 0.1113 | 0.1207 | 0.0727 | 0.0793 | 0.1113 | 0.1116 | 0.6157 | 0.5879 | 0.0003 | 0.0009 | 0.0029 | 0.0128 | 0.0565 | 0.0983 | 0.0684 | 0.1010 | 0.6588 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 666 | 842 | | 12884 | 27221 | 219.0 | 58.92 | 118.73 | 205.47 | 152 | 171 | 185 | 199 | 212 | 227 | 245 | 268 | 298 | 0.0499 | 1359 | 0.808 | 193.62 | 44.05 | 2 | 0.0354 | 456 | 0.0008 | 46.64 | 7.460 | 0.1768 | 51441.8 | 12900000 | 3430000000 | 964000000000 | 0.4180 | 0.2281 | 0.0003 | 0.0001 | 0.0020 | 0.0000 | 0.0075 | 0.0004 | 0.0271 | 0.0027 | 0.0783 | 0.0206 | 0.1403 | 0.0412 | 0.1412 | 0.0459 | 0.1709 | 0.0684 | 0.4325 | 0.8207 | 0.0001 | 0.0000 | 0.0013 | 0.0000 | 0.0023 | 0.0000 | 0.0103 | 0.0014 | 0.0303 | 0.0115 | 0.0505 | 0.0181 | 0.0596 | 0.0180 | 0.0775 | 0.0275 | 0.7681 | 0.9236 | 0.0028 | 0.0068 | 0.0028 | 0.0184 | 0.0137 | 0.0261 | 0.0439 | 0.0812 | 0.0847 | 0.1285 | 0.1612 | 0.1865 | 0.1135 | 0.0889 | 0.1377 | 0.1449 | 0.4398 | 0.3188 | 0.0017 | 0.0044 | 0.0094 | 0.0269 | 0.0584 | 0.0906 | 0.0952 | 0.1178 | 0.5957 | 12 | 14 | 16 | 19 | 23 | 35 | 81 | 186 | 369 | 0.1090 | 28.98 | 4.298 | 0.6029 | 56311.6 | 43400000 | 43600000000 | 52400000000000 | 0.4887 | 0.1540 | 0.1380 | 0.0057 | 0.3027 | 0.0505 | 0.2534 | 0.2149 | 0.1170 | 0.1937 | 0.0888 | 0.2013 | 0.0605 | 0.1398 | 0.0282 | 0.0765 | 0.0105 | 0.0629 | 0.0008 | 0.0547 | 0.0000 | 0.0004 | 0.0018 | 0.0008 | 0.0016 | 0.0015 | 0.0149 | 0.0108 | 0.0607 | 0.0575 | 0.0912 | 0.0799 | 0.0683 | 0.0568 | 0.1015 | 0.0892 | 0.6600 | 0.7031 | 0.0005 | 0.0000 | 0.0008 | 0.0012 | 0.0040 | 0.0058 | 0.0208 | 0.0226 | 0.0784 | 0.0804 | 0.1103 | 0.1258 | 0.0842 | 0.0911 | 0.1132 | 0.1227 | 0.5879 | 0.5503 | 0.0004 | 0.0011 | 0.0027 | 0.0160 | 0.0680 | 0.1060 | 0.0721 | 0.1158 | 0.6178 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 171 | 227 | | 13156 | 26560 | 216.3 | 55.08 | 143.33 | 196.83 | 147 | 172 | 189 | 203 | 217 | 231 | 246 | 263 | 286 | 0.0570 | 1514 | 0.695 | 170.21 | 47.54 | 3 | 0.0364 | 479 | 0.0008 | 42.66 | 7.414 | 0.1765 | 49810.3 | 12100000 | 3040000000 | 797000000000 | 0.4175 | 0.2260 | 0.0007 | 0.0001 | 0.0014 | 0.0001 | 0.0076 | 0.0009 | 0.0228 | 0.0052 | 0.0655 | 0.0153 | 0.1188 | 0.0349 | 0.1344 | 0.0418 | 0.1753 | 0.0659 | 0.4735 | 0.8359 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0004 | 0.0075 | 0.0020 | 0.0220 | 0.0098 | 0.0398 | 0.0182 | 0.0480 | 0.0148 | 0.0644 | 0.0241 | 0.8168 | 0.9308 | 0.0028 | 0.0282 | 0.0118 | 0.0267 | 0.0277 | 0.0847 | 0.0602 | 0.1278 | 0.0906 | 0.1798 | 0.1387 | 0.1575 | 0.1280 | 0.1189 | 0.1505 | 0.1218 | 0.3898 | 0.1545 | 0.0012 | 0.0034 | 0.0079 | 0.0230 | 0.0477 | 0.0880 | 0.0938 | 0.1052 | 0.6296 | 16 | 19 | 22 | 26 | 40 | 80 | 154 | 256 | 424 | 0.0499 | 24.57 | 5.020 | 0.5076 | 59283.3 | 35800000 | 26400000000 | 22500000000000 | 0.6077 | 0.0916 | 0.0465 | 0.0024 | 0.1573 | 0.0221 | 0.2370 | 0.0945 | 0.1899 | 0.1299 | 0.1567 | 0.1853 | 0.1107 | 0.1877 | 0.0559 | 0.1296 | 0.0288 | 0.1216 | 0.0172 | 0.1270 | 0.0004 | 0.0003 | 0.0007 | 0.0014 | 0.0025 | 0.0019 | 0.0149 | 0.0139 | 0.0556 | 0.0499 | 0.0753 | 0.0693 | 0.0592 | 0.0511 | 0.0899 | 0.0801 | 0.7015 | 0.7321 | 0.0005 | 0.0015 | 0.0016 | 0.0014 | 0.0046 | 0.0059 | 0.0219 | 0.0234 | 0.0658 | 0.0751 | 0.1028 | 0.1190 | 0.0811 | 0.0870 | 0.1118 | 0.1202 | 0.6099 | 0.5665 | 0.0007 | 0.0013 | 0.0027 | 0.0190 | 0.0556 | 0.0905 | 0.0669 | 0.0992 | 0.6642 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 840 | 632 | | 7599 | 25331 | 439.9 | 83.79 | 168.72 | 276.45 | 340 | 369 | 390 | 410 | 429 | 450 | 476 | 508 | 555 | 0.0492 | 1247 | 1.002 | 122.50 | 43.46 | 1 | 0.0425 | 323 | 0.0006 | 77.97 | 7.638 | 0.1430 | 200554.0 | 94700000 | 46300000000 | 23400000000000 | 0.4550 | 0.1957 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0026 | 0.0000 | 0.0094 | 0.0007 | 0.0535 | 0.0144 | 0.1165 | 0.0319 | 0.1324 | 0.0357 | 0.1602 | 0.0471 | 0.5253 | 0.8703 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0024 | 0.0000 | 0.0278 | 0.0111 | 0.0578 | 0.0182 | 0.0625 | 0.0137 | 0.0881 | 0.0211 | 0.7604 | 0.9358 | 0.0025 | 0.0077 | 0.0101 | 0.0193 | 0.0126 | 0.0386 | 0.0666 | 0.2278 | 0.1265 | 0.2162 | 0.1678 | 0.2355 | 0.1273 | 0.1042 | 0.1669 | 0.0965 | 0.3196 | 0.0541 | 0.0012 | 0.0026 | 0.0096 | 0.0417 | 0.0858 | 0.1214 | 0.1033 | 0.1219 | 0.5125 | 6 | 7 | 9 | 11 | 16 | 45 | 143 | 328 | 583 | 0.1315 | 51.22 | 4.587 | 0.5228 | 104886.0 | 87500000 | 85800000000 | 94300000000000 | 0.5042 | 0.1314 | 0.1174 | 0.0045 | 0.3070 | 0.0508 | 0.2798 | 0.2324 | 0.1277 | 0.2165 | 0.1108 | 0.1884 | 0.0404 | 0.1303 | 0.0113 | 0.0944 | 0.0038 | 0.0477 | 0.0019 | 0.0350 | 0.0001 | 0.0001 | 0.0012 | 0.0004 | 0.0026 | 0.0011 | 0.0093 | 0.0084 | 0.0522 | 0.0465 | 0.0772 | 0.0740 | 0.0532 | 0.0513 | 0.0848 | 0.0734 | 0.7194 | 0.7448 | 0.0001 | 0.0002 | 0.0007 | 0.0008 | 0.0021 | 0.0027 | 0.0093 | 0.0091 | 0.0560 | 0.0627 | 0.0918 | 0.1001 | 0.0656 | 0.0705 | 0.1066 | 0.1206 | 0.6678 | 0.6332 | 0.0003 | 0.0015 | 0.0032 | 0.0089 | 0.0529 | 0.0819 | 0.0600 | 0.0898 | 0.7015 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 170 | 550 | | 8750 | 8424 | 502.4 | 87.96 | 41.36 | 73.23 | 382 | 421 | 449 | 477 | 504 | 533 | 561 | 587 | 616 | 0.0991 | 835 | 0.776 | 84.48 | 24.52 | 5 | 0.0277 | 242 | 0.0010 | 31.96 | 7.187 | 0.2170 | 260103.0 | 138000000 | 75400000000 | 41900000000000 | 0.4172 | 0.2234 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0032 | 0.0000 | 0.0111 | 0.0005 | 0.0476 | 0.0114 | 0.0760 | 0.0187 | 0.0904 | 0.0131 | 0.1317 | 0.0244 | 0.6373 | 0.9319 | 0.0003 | 0.0000 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0043 | 0.0005 | 0.0214 | 0.0113 | 0.0331 | 0.0183 | 0.0365 | 0.0119 | 0.0525 | 0.0214 | 0.8509 | 0.9367 | 0.0126 | 0.1000 | 0.0126 | 0.2000 | 0.0356 | 0.5000 | 0.0617 | 0.2000 | 0.1146 | 0.0000 | 0.1486 | 0.0000 | 0.1328 | 0.0000 | 0.1518 | 0.0000 | 0.3296 | 0.0000 | 0.0014 | 0.0023 | 0.0063 | 0.0160 | 0.0405 | 0.0657 | 0.0673 | 0.0822 | 0.7184 | 8 | 10 | 12 | 13 | 16 | 20 | 28 | 44 | 98 | 0.1584 | 2.61 | 3.052 | 0.7597 | 7073.0 | 2420000 | 1080000000 | 547000000000 | 0.6438 | 0.0750 | 0.0266 | 0.0119 | 0.0620 | 0.0252 | 0.1004 | 0.0365 | 0.1492 | 0.0697 | 0.1905 | 0.1048 | 0.1418 | 0.1287 | 0.1536 | 0.1301 | 0.0960 | 0.1858 | 0.0798 | 0.3072 | 0.0055 | 0.0063 | 0.0104 | 0.0116 | 0.0127 | 0.0137 | 0.0209 | 0.0256 | 0.0563 | 0.0460 | 0.0700 | 0.0674 | 0.0691 | 0.0593 | 0.1004 | 0.1092 | 0.6547 | 0.6608 | 0.0000 | 0.0045 | 0.0052 | 0.0037 | 0.0085 | 0.0082 | 0.0184 | 0.0231 | 0.0636 | 0.0723 | 0.0932 | 0.0835 | 0.0636 | 0.0776 | 0.1122 | 0.1148 | 0.6352 | 0.6122 | 0.0011 | 0.0038 | 0.0098 | 0.0235 | 0.0573 | 0.0742 | 0.0770 | 0.1070 | 0.6463 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 472 | 365 | | 10152 | 16333 | 306.6 | 57.54 | 224.30 | 196.37 | 237 | 256 | 271 | 285 | 301 | 317 | 336 | 357 | 386 | 0.0678 | 1107 | 0.822 | 136.62 | 44.05 | 1 | 0.0396 | 402 | 0.0006 | 77.66 | 7.651 | 0.1416 | 97320.9 | 31900000 | 10800000000 | 3780000000000 | 0.4559 | 0.2016 | 0.0007 | 0.0000 | 0.0006 | 0.0000 | 0.0038 | 0.0001 | 0.0147 | 0.0006 | 0.0559 | 0.0105 | 0.1218 | 0.0272 | 0.1337 | 0.0260 | 0.1584 | 0.0428 | 0.5103 | 0.8928 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0036 | 0.0001 | 0.0257 | 0.0079 | 0.0578 | 0.0184 | 0.0582 | 0.0109 | 0.0841 | 0.0197 | 0.7693 | 0.9430 | 0.0025 | 0.0159 | 0.0101 | 0.0518 | 0.0297 | 0.0876 | 0.0802 | 0.2072 | 0.1723 | 0.1952 | 0.1799 | 0.1474 | 0.1187 | 0.1036 | 0.1503 | 0.0558 | 0.2563 | 0.1355 | 0.0008 | 0.0025 | 0.0127 | 0.0317 | 0.0909 | 0.1254 | 0.1094 | 0.1379 | 0.4885 | 22 | 46 | 83 | 125 | 173 | 229 | 295 | 376 | 500 | 0.0068 | 69.26 | 6.886 | 0.2834 | 88869.9 | 46400000 | 29000000000 | 20500000000000 | 0.5451 | 0.1262 | 0.0275 | 0.0020 | 0.1405 | 0.0066 | 0.2540 | 0.0553 | 0.1753 | 0.1106 | 0.1531 | 0.1890 | 0.1086 | 0.2034 | 0.0715 | 0.1379 | 0.0376 | 0.1361 | 0.0319 | 0.1591 | 0.0004 | 0.0006 | 0.0004 | 0.0007 | 0.0035 | 0.0023 | 0.0163 | 0.0094 | 0.0680 | 0.0540 | 0.1119 | 0.0867 | 0.0864 | 0.0698 | 0.1192 | 0.1056 | 0.5940 | 0.6708 | 0.0002 | 0.0013 | 0.0020 | 0.0036 | 0.0087 | 0.0107 | 0.0296 | 0.0330 | 0.1018 | 0.1162 | 0.1498 | 0.1759 | 0.1073 | 0.1119 | 0.1433 | 0.1478 | 0.4572 | 0.3996 | 0.0004 | 0.0016 | 0.0045 | 0.0181 | 0.0879 | 0.1310 | 0.0994 | 0.1385 | 0.5186 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 328 | 685 | | 3310 | 17319 | 115.5 | 44.52 | 5.43 | 1.99 | 62 | 70 | 80 | 93 | 109 | 124 | 140 | 161 | 181 | 0.0577 | 999 | 0.991 | 31.40 | 10.77 | 2 | 0.0266 | 88 | 0.0050 | 4.21 | 5.619 | 0.4414 | 15310.3 | 2260000 | 362000000 | 61100000000 | 0.3498 | 0.2779 | 0.0021 | 0.0010 | 0.0072 | 0.0039 | 0.0123 | 0.0093 | 0.0349 | 0.0181 | 0.0739 | 0.0366 | 0.1242 | 0.0439 | 0.1232 | 0.0649 | 0.1828 | 0.0825 | 0.4394 | 0.7399 | 0.0005 | 0.0007 | 0.0015 | 0.0026 | 0.0035 | 0.0048 | 0.0089 | 0.0096 | 0.0212 | 0.0177 | 0.0227 | 0.0184 | 0.0257 | 0.0302 | 0.0420 | 0.0350 | 0.8741 | 0.8809 | 0.0010 | 0.0000 | 0.0019 | 0.0045 | 0.0086 | 0.0106 | 0.0209 | 0.0151 | 0.0409 | 0.0452 | 0.0571 | 0.0603 | 0.0523 | 0.0724 | 0.0647 | 0.0799 | 0.7526 | 0.7119 | 0.0013 | 0.0000 | 0.0013 | 0.0097 | 0.0232 | 0.0387 | 0.0290 | 0.0574 | 0.8395 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.2714 | 0.47 | 1.049 | 0.6358 | 33.5 | 227.156 | 1669.44 | 13153.9 | 0.4485 | 0.2089 | 0.0313 | 0.0023 | 0.0940 | 0.0125 | 0.1602 | 0.0406 | 0.2077 | 0.0829 | 0.2080 | 0.1416 | 0.1737 | 0.2164 | 0.0888 | 0.2463 | 0.0321 | 0.1826 | 0.0043 | 0.0747 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0030 | 0.0008 | 0.0099 | 0.0050 | 0.0301 | 0.0153 | 0.0780 | 0.0258 | 0.2017 | 0.0630 | 0.3485 | 0.2345 | 0.3287 | 0.6554 | 0.0177 | 0.0768 | 0.0775 | 0.1643 | 0.1302 | 0.2136 | 0.1742 | 0.2130 | 0.1942 | 0.1573 | 0.1860 | 0.0951 | 0.1327 | 0.0548 | 0.0683 | 0.0195 | 0.0192 | 0.0057 | 0.0007 | 0.0109 | 0.0459 | 0.1123 | 0.1876 | 0.2387 | 0.2118 | 0.1393 | 0.0528 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1218 | 150 | | 8328 | 20825 | 278.7 | 60.80 | 290.87 | 439.80 | 204 | 240 | 258 | 272 | 285 | 298 | 311 | 327 | 347 | 0.0520 | 1082 | 0.814 | 131.22 | 25.94 | 2 | 0.0359 | 299 | 0.0015 | 25.68 | 6.861 | 0.2311 | 81369.2 | 24600000 | 7610000000 | 2410000000000 | 0.4056 | 0.2353 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0106 | 0.0006 | 0.0413 | 0.0112 | 0.0811 | 0.0241 | 0.0864 | 0.0135 | 0.1377 | 0.0258 | 0.6381 | 0.9247 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0001 | 0.0143 | 0.0100 | 0.0289 | 0.0185 | 0.0247 | 0.0084 | 0.0466 | 0.0146 | 0.8830 | 0.9483 | 0.0055 | 0.0364 | 0.0234 | 0.0182 | 0.0343 | 0.0455 | 0.0810 | 0.1273 | 0.1262 | 0.1364 | 0.1752 | 0.3091 | 0.1371 | 0.0909 | 0.1269 | 0.0727 | 0.2905 | 0.1636 | 0.0015 | 0.0033 | 0.0074 | 0.0220 | 0.0435 | 0.0863 | 0.0844 | 0.1177 | 0.6340 | 7 | 10 | 13 | 17 | 28 | 115 | 308 | 594 | 1020 | 0.0848 | 69.35 | 5.353 | 0.4886 | 278017.0 | 336000000 | 456000000000 | 669000000000000 | 0.5138 | 0.1645 | 0.0468 | 0.0052 | 0.1680 | 0.0170 | 0.2305 | 0.1168 | 0.1460 | 0.1394 | 0.1433 | 0.1748 | 0.1148 | 0.1667 | 0.0661 | 0.1295 | 0.0487 | 0.1130 | 0.0358 | 0.1375 | 0.0003 | 0.0003 | 0.0000 | 0.0003 | 0.0009 | 0.0009 | 0.0078 | 0.0073 | 0.0402 | 0.0330 | 0.0717 | 0.0659 | 0.0532 | 0.0476 | 0.0763 | 0.0708 | 0.7497 | 0.7740 | 0.0002 | 0.0011 | 0.0003 | 0.0020 | 0.0034 | 0.0050 | 0.0145 | 0.0131 | 0.0489 | 0.0487 | 0.0799 | 0.0830 | 0.0597 | 0.0625 | 0.0824 | 0.0882 | 0.7106 | 0.6963 | 0.0002 | 0.0002 | 0.0019 | 0.0108 | 0.0438 | 0.0821 | 0.0547 | 0.0780 | 0.7283 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 989 | 569 | | 11363 | 17154 | 435.1 | 102.14 | 100.15 | 106.92 | 319 | 350 | 374 | 396 | 420 | 445 | 475 | 519 | 577 | 0.0642 | 1102 | 1.214 | 111.97 | 45.88 | 1 | 0.0259 | 294 | 0.0008 | 45.10 | 7.457 | 0.1791 | 199761.0 | 96800000 | 49400000000 | 26500000000000 | 0.4356 | 0.2162 | 0.0004 | 0.0001 | 0.0023 | 0.0001 | 0.0049 | 0.0006 | 0.0187 | 0.0024 | 0.0547 | 0.0168 | 0.1228 | 0.0359 | 0.1224 | 0.0361 | 0.1532 | 0.0537 | 0.5207 | 0.8544 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0001 | 0.0074 | 0.0009 | 0.0262 | 0.0104 | 0.0589 | 0.0186 | 0.0605 | 0.0168 | 0.0788 | 0.0275 | 0.7659 | 0.9258 | 0.0027 | 0.0014 | 0.0063 | 0.0068 | 0.0094 | 0.0315 | 0.0367 | 0.0876 | 0.0823 | 0.1231 | 0.1360 | 0.1737 | 0.0922 | 0.1081 | 0.1128 | 0.1231 | 0.5217 | 0.3447 | 0.0010 | 0.0012 | 0.0068 | 0.0319 | 0.0806 | 0.1097 | 0.0930 | 0.1123 | 0.5635 | 7 | 11 | 20 | 37 | 62 | 94 | 132 | 180 | 248 | 0.0392 | 11.55 | 4.988 | 0.4732 | 21460.8 | 6340000 | 2300000000 | 971000000000 | 0.5515 | 0.1124 | 0.0581 | 0.0039 | 0.2164 | 0.0200 | 0.2885 | 0.1377 | 0.1593 | 0.1383 | 0.1259 | 0.1997 | 0.0867 | 0.1917 | 0.0344 | 0.1180 | 0.0237 | 0.1032 | 0.0070 | 0.0874 | 0.0001 | 0.0001 | 0.0005 | 0.0005 | 0.0012 | 0.0003 | 0.0130 | 0.0092 | 0.0667 | 0.0520 | 0.1087 | 0.0943 | 0.0812 | 0.0656 | 0.1186 | 0.1022 | 0.6099 | 0.6759 | 0.0005 | 0.0012 | 0.0010 | 0.0029 | 0.0045 | 0.0074 | 0.0218 | 0.0286 | 0.0939 | 0.1036 | 0.1590 | 0.1785 | 0.0997 | 0.1088 | 0.1431 | 0.1573 | 0.4763 | 0.4118 | 0.0003 | 0.0006 | 0.0018 | 0.0174 | 0.0781 | 0.1316 | 0.0944 | 0.1376 | 0.5381 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 267 | 437 | | 13592 | 31269 | 301.0 | 63.57 | 169.76 | 203.21 | 225 | 246 | 263 | 279 | 295 | 313 | 331 | 353 | 386 | 0.0450 | 1407 | 0.991 | 116.62 | 32.28 | 1 | 0.0211 | 287 | 0.0005 | 80.82 | 7.811 | 0.1322 | 94652.1 | 31000000 | 10600000000 | 3760000000000 | 0.4501 | 0.1998 | 0.0000 | 0.0000 | 0.0006 | 0.0002 | 0.0033 | 0.0002 | 0.0168 | 0.0009 | 0.0656 | 0.0133 | 0.1325 | 0.0320 | 0.1576 | 0.0360 | 0.1861 | 0.0572 | 0.4376 | 0.8603 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0001 | 0.0063 | 0.0004 | 0.0276 | 0.0084 | 0.0557 | 0.0188 | 0.0701 | 0.0154 | 0.0900 | 0.0249 | 0.7485 | 0.9321 | 0.0051 | 0.0171 | 0.0085 | 0.0240 | 0.0315 | 0.0719 | 0.0817 | 0.1199 | 0.1430 | 0.1747 | 0.1750 | 0.1695 | 0.1222 | 0.0925 | 0.1384 | 0.1318 | 0.2946 | 0.1986 | 0.0011 | 0.0024 | 0.0080 | 0.0318 | 0.0799 | 0.1235 | 0.1033 | 0.1392 | 0.5107 | 16 | 20 | 25 | 36 | 65 | 122 | 216 | 331 | 478 | 0.0295 | 54.42 | 5.957 | 0.4239 | 70109.3 | 38900000 | 25400000000 | 18600000000000 | 0.4659 | 0.1579 | 0.1220 | 0.0013 | 0.3239 | 0.0267 | 0.3147 | 0.2497 | 0.1092 | 0.2318 | 0.0683 | 0.1799 | 0.0358 | 0.1321 | 0.0147 | 0.0764 | 0.0073 | 0.0559 | 0.0041 | 0.0461 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0024 | 0.0013 | 0.0139 | 0.0099 | 0.0651 | 0.0580 | 0.1046 | 0.0910 | 0.0733 | 0.0686 | 0.1102 | 0.1024 | 0.6295 | 0.6682 | 0.0002 | 0.0003 | 0.0011 | 0.0020 | 0.0039 | 0.0045 | 0.0192 | 0.0256 | 0.0810 | 0.0887 | 0.1246 | 0.1262 | 0.0858 | 0.0977 | 0.1320 | 0.1374 | 0.5522 | 0.5175 | 0.0001 | 0.0012 | 0.0027 | 0.0147 | 0.0721 | 0.1162 | 0.0811 | 0.1158 | 0.5962 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1125 | 641 | | 11752 | 25342 | 232.5 | 61.19 | 170.59 | 255.96 | 162 | 186 | 201 | 215 | 228 | 242 | 257 | 278 | 310 | 0.0510 | 1293 | 1.092 | 30.46 | 9.43 | 3 | 0.0062 | 73 | 0.0008 | 52.10 | 7.510 | 0.1713 | 57786.2 | 15300000 | 4280000000 | 1270000000000 | 0.4266 | 0.2087 | 0.0003 | 0.0000 | 0.0011 | 0.0002 | 0.0038 | 0.0004 | 0.0137 | 0.0016 | 0.0570 | 0.0194 | 0.1221 | 0.0376 | 0.1242 | 0.0374 | 0.1725 | 0.0532 | 0.5053 | 0.8503 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0015 | 0.0000 | 0.0056 | 0.0005 | 0.0238 | 0.0113 | 0.0480 | 0.0188 | 0.0513 | 0.0158 | 0.0752 | 0.0235 | 0.7940 | 0.9300 | 0.0039 | 0.0023 | 0.0117 | 0.0081 | 0.0174 | 0.0151 | 0.0516 | 0.0755 | 0.0951 | 0.1231 | 0.1428 | 0.1649 | 0.0872 | 0.1115 | 0.1228 | 0.1161 | 0.4674 | 0.3833 | 0.0018 | 0.0029 | 0.0093 | 0.0250 | 0.0622 | 0.0988 | 0.0949 | 0.1131 | 0.5921 | 9 | 12 | 17 | 32 | 58 | 95 | 152 | 272 | 534 | 0.0689 | 34.29 | 5.267 | 0.5297 | 94612.1 | 77200000 | 75700000000 | 83200000000000 | 0.3585 | 0.3278 | 0.0395 | 0.0012 | 0.1512 | 0.0108 | 0.2256 | 0.0794 | 0.1461 | 0.1072 | 0.1502 | 0.1684 | 0.1169 | 0.1823 | 0.0707 | 0.1281 | 0.0608 | 0.1168 | 0.0390 | 0.2056 | 0.0006 | 0.0003 | 0.0021 | 0.0014 | 0.0038 | 0.0026 | 0.0153 | 0.0136 | 0.0581 | 0.0480 | 0.0869 | 0.0812 | 0.0666 | 0.0586 | 0.0861 | 0.0828 | 0.6805 | 0.7116 | 0.0002 | 0.0007 | 0.0019 | 0.0034 | 0.0056 | 0.0081 | 0.0251 | 0.0236 | 0.0640 | 0.0649 | 0.0941 | 0.0908 | 0.0674 | 0.0685 | 0.0855 | 0.0777 | 0.6563 | 0.6622 | 0.0007 | 0.0013 | 0.0062 | 0.0194 | 0.0623 | 0.0938 | 0.0645 | 0.0859 | 0.6660 | ||
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1104 | 606 | | 7792 | 17317 | 455.1 | 84.64 | 91.04 | 159.85 | 350 | 380 | 405 | 428 | 449 | 472 | 497 | 528 | 568 | 0.0587 | 1017 | 0.843 | 136.49 | 39.96 | 1 | 0.0508 | 396 | 0.0009 | 41.02 | 7.256 | 0.1774 | 214248.0 | 104000000 | 52400000000 | 27200000000000 | 0.4390 | 0.2040 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0136 | 0.0005 | 0.0498 | 0.0107 | 0.1097 | 0.0237 | 0.1108 | 0.0193 | 0.1486 | 0.0344 | 0.5627 | 0.9113 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0024 | 0.0000 | 0.0058 | 0.0004 | 0.0229 | 0.0095 | 0.0478 | 0.0189 | 0.0484 | 0.0112 | 0.0635 | 0.0227 | 0.8089 | 0.9373 | 0.0050 | 0.0153 | 0.0059 | 0.0153 | 0.0243 | 0.0458 | 0.0703 | 0.1756 | 0.1456 | 0.1221 | 0.1816 | 0.1603 | 0.1364 | 0.0916 | 0.1356 | 0.1069 | 0.2954 | 0.2672 | 0.0019 | 0.0038 | 0.0059 | 0.0261 | 0.0676 | 0.1051 | 0.0997 | 0.1070 | 0.5829 | 5 | 6 | 7 | 9 | 11 | 25 | 76 | 148 | 295 | 0.1599 | 22.17 | 4.036 | 0.5973 | 33837.1 | 18800000 | 12800000000 | 9900000000000 | 0.6360 | 0.0673 | 0.0357 | 0.0021 | 0.1417 | 0.0167 | 0.2200 | 0.0889 | 0.1536 | 0.1271 | 0.1497 | 0.1836 | 0.1249 | 0.1857 | 0.0694 | 0.1130 | 0.0565 | 0.1130 | 0.0486 | 0.1700 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0006 | 0.0003 | 0.0113 | 0.0062 | 0.0430 | 0.0382 | 0.0708 | 0.0689 | 0.0549 | 0.0430 | 0.0815 | 0.0753 | 0.7371 | 0.7679 | 0.0002 | 0.0000 | 0.0005 | 0.0010 | 0.0049 | 0.0052 | 0.0117 | 0.0160 | 0.0608 | 0.0640 | 0.0963 | 0.1006 | 0.0629 | 0.0694 | 0.0974 | 0.1091 | 0.6653 | 0.6349 | 0.0002 | 0.0006 | 0.0023 | 0.0121 | 0.0489 | 0.0886 | 0.0606 | 0.0917 | 0.6949 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 709 | 307 | | 13145 | 33263 | 215.6 | 52.79 | 151.28 | 220.31 | 149 | 174 | 189 | 203 | 216 | 228 | 242 | 259 | 283 | 0.0407 | 1355 | 1.265 | 23.41 | 8.25 | 1 | 0.0043 | 57 | 0.0010 | 34.06 | 7.246 | 0.2053 | 49257.3 | 11800000 | 2960000000 | 769000000000 | 0.3831 | 0.2579 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0040 | 0.0005 | 0.0168 | 0.0025 | 0.0464 | 0.0130 | 0.0932 | 0.0319 | 0.1084 | 0.0316 | 0.1447 | 0.0480 | 0.5842 | 0.8725 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0014 | 0.0001 | 0.0053 | 0.0012 | 0.0169 | 0.0077 | 0.0331 | 0.0189 | 0.0378 | 0.0116 | 0.0514 | 0.0186 | 0.8537 | 0.9419 | 0.0054 | 0.0148 | 0.0050 | 0.0411 | 0.0204 | 0.0542 | 0.0549 | 0.1117 | 0.0976 | 0.1215 | 0.1187 | 0.1560 | 0.1145 | 0.1034 | 0.1287 | 0.1051 | 0.4549 | 0.2923 | 0.0014 | 0.0017 | 0.0065 | 0.0214 | 0.0510 | 0.0797 | 0.0892 | 0.1055 | 0.6436 | 12 | 15 | 20 | 31 | 50 | 92 | 148 | 246 | 442 | 0.0346 | 37.24 | 5.501 | 0.4820 | 71418.1 | 52500000 | 49100000000 | 54400000000000 | 0.4267 | 0.2463 | 0.0312 | 0.0012 | 0.1250 | 0.0165 | 0.2039 | 0.0728 | 0.1419 | 0.0958 | 0.1495 | 0.1578 | 0.1419 | 0.1887 | 0.0914 | 0.1192 | 0.0623 | 0.1242 | 0.0530 | 0.2238 | 0.0005 | 0.0003 | 0.0020 | 0.0009 | 0.0057 | 0.0031 | 0.0160 | 0.0110 | 0.0513 | 0.0476 | 0.0861 | 0.0794 | 0.0620 | 0.0504 | 0.0781 | 0.0712 | 0.6982 | 0.7362 | 0.0005 | 0.0004 | 0.0014 | 0.0037 | 0.0064 | 0.0063 | 0.0183 | 0.0174 | 0.0625 | 0.0699 | 0.1084 | 0.1182 | 0.0749 | 0.0836 | 0.1034 | 0.1020 | 0.6243 | 0.5984 | 0.0008 | 0.0015 | 0.0050 | 0.0158 | 0.0576 | 0.0968 | 0.0701 | 0.0894 | 0.6629 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 798 | 428 | | 27432 | 45118 | 211.1 | 59.97 | 98.82 | 173.21 | 140 | 162 | 179 | 194 | 208 | 223 | 239 | 258 | 287 | 0.0427 | 1927 | 0.804 | 104.04 | 21.19 | 1 | 0.0082 | 226 | 0.0007 | 43.54 | 7.545 | 0.1862 | 48158.5 | 11800000 | 3050000000 | 838000000000 | 0.4170 | 0.2298 | 0.0009 | 0.0000 | 0.0014 | 0.0001 | 0.0072 | 0.0005 | 0.0254 | 0.0026 | 0.0661 | 0.0188 | 0.1224 | 0.0410 | 0.1361 | 0.0439 | 0.1737 | 0.0674 | 0.4667 | 0.8259 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0001 | 0.0072 | 0.0009 | 0.0239 | 0.0093 | 0.0448 | 0.0189 | 0.0494 | 0.0177 | 0.0650 | 0.0292 | 0.8061 | 0.9239 | 0.0049 | 0.0049 | 0.0082 | 0.0175 | 0.0196 | 0.0265 | 0.0469 | 0.0746 | 0.0894 | 0.1169 | 0.1266 | 0.1677 | 0.1090 | 0.1102 | 0.1271 | 0.1250 | 0.4683 | 0.3566 | 0.0014 | 0.0023 | 0.0066 | 0.0227 | 0.0535 | 0.0917 | 0.0877 | 0.1135 | 0.6206 | 10 | 12 | 14 | 16 | 20 | 29 | 54 | 137 | 332 | 0.1819 | 23.17 | 3.891 | 0.6587 | 39767.1 | 24100000 | 17400000000 | 14100000000000 | 0.4082 | 0.2647 | 0.1462 | 0.0039 | 0.3078 | 0.0465 | 0.2795 | 0.2378 | 0.1040 | 0.2151 | 0.0818 | 0.2042 | 0.0463 | 0.1441 | 0.0206 | 0.0647 | 0.0093 | 0.0494 | 0.0046 | 0.0343 | 0.0000 | 0.0000 | 0.0009 | 0.0006 | 0.0015 | 0.0011 | 0.0142 | 0.0095 | 0.0704 | 0.0604 | 0.0987 | 0.0930 | 0.0678 | 0.0551 | 0.1104 | 0.0943 | 0.6360 | 0.6860 | 0.0003 | 0.0000 | 0.0017 | 0.0017 | 0.0033 | 0.0043 | 0.0185 | 0.0216 | 0.0848 | 0.0897 | 0.1211 | 0.1251 | 0.0804 | 0.0863 | 0.1188 | 0.1212 | 0.5710 | 0.5502 | 0.0001 | 0.0006 | 0.0030 | 0.0167 | 0.0751 | 0.1185 | 0.0740 | 0.1117 | 0.6002 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 357 | 710 | | 4921 | 10409 | 582.7 | 104.04 | 163.34 | 169.37 | 446 | 495 | 525 | 552 | 579 | 603 | 634 | 667 | 722 | 0.0790 | 822 | 1.185 | 96.46 | 39.82 | 1 | 0.0528 | 260 | 0.0007 | 60.83 | 7.459 | 0.1592 | 350308.0 | 217000000 | 138000000000 | 90400000000000 | 0.4237 | 0.2197 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0017 | 0.0004 | 0.0084 | 0.0015 | 0.0427 | 0.0174 | 0.0858 | 0.0245 | 0.0936 | 0.0272 | 0.1375 | 0.0367 | 0.6295 | 0.8923 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0031 | 0.0002 | 0.0252 | 0.0151 | 0.0417 | 0.0191 | 0.0370 | 0.0165 | 0.0620 | 0.0242 | 0.8301 | 0.9248 | 0.0075 | 0.0326 | 0.0090 | 0.0000 | 0.0271 | 0.0761 | 0.0827 | 0.1739 | 0.1203 | 0.1739 | 0.1399 | 0.2391 | 0.1068 | 0.1413 | 0.1053 | 0.1087 | 0.4015 | 0.0543 | 0.0017 | 0.0034 | 0.0029 | 0.0253 | 0.0623 | 0.1077 | 0.1098 | 0.1355 | 0.5513 | 11 | 14 | 21 | 52 | 104 | 160 | 229 | 315 | 422 | 0.0230 | 43.80 | 6.033 | 0.3963 | 55363.2 | 23600000 | 11400000000 | 6020000000000 | 0.5634 | 0.1337 | 0.0386 | 0.0005 | 0.1929 | 0.0101 | 0.2671 | 0.0648 | 0.1977 | 0.1411 | 0.1244 | 0.2046 | 0.0839 | 0.1945 | 0.0473 | 0.1177 | 0.0260 | 0.1172 | 0.0222 | 0.1494 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0024 | 0.0004 | 0.0120 | 0.0066 | 0.0468 | 0.0368 | 0.0843 | 0.0643 | 0.0646 | 0.0509 | 0.1058 | 0.0885 | 0.6839 | 0.7518 | 0.0008 | 0.0003 | 0.0011 | 0.0016 | 0.0036 | 0.0038 | 0.0149 | 0.0166 | 0.0618 | 0.0787 | 0.1118 | 0.1234 | 0.0845 | 0.0918 | 0.1220 | 0.1321 | 0.5995 | 0.5516 | 0.0005 | 0.0010 | 0.0027 | 0.0124 | 0.0553 | 0.0981 | 0.0694 | 0.1131 | 0.6476 | ||
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 802 | 490 | | 8351 | 22610 | 575.7 | 122.92 | 67.00 | 140.53 | 447 | 481 | 507 | 530 | 554 | 578 | 610 | 654 | 726 | 0.0503 | 1138 | 0.892 | 99.02 | 25.02 | 1 | 0.0290 | 242 | 0.0006 | 85.09 | 7.659 | 0.1388 | 346489.0 | 219000000 | 147000000000 | 104000000000000 | 0.4366 | 0.2123 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0000 | 0.0107 | 0.0008 | 0.0464 | 0.0130 | 0.0968 | 0.0349 | 0.1084 | 0.0240 | 0.1476 | 0.0372 | 0.5879 | 0.8901 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0054 | 0.0000 | 0.0254 | 0.0090 | 0.0547 | 0.0192 | 0.0514 | 0.0107 | 0.0823 | 0.0199 | 0.7799 | 0.9412 | 0.0017 | 0.0022 | 0.0111 | 0.0066 | 0.0085 | 0.0087 | 0.0752 | 0.0502 | 0.1265 | 0.1397 | 0.1282 | 0.1790 | 0.0966 | 0.0830 | 0.1154 | 0.1397 | 0.4368 | 0.3908 | 0.0018 | 0.0062 | 0.0117 | 0.0486 | 0.0847 | 0.1260 | 0.0923 | 0.1116 | 0.5173 | 5 | 6 | 7 | 8 | 9 | 11 | 17 | 73 | 234 | 0.2107 | 10.92 | 3.086 | 0.6429 | 24238.2 | 13000000 | 8460000000 | 6260000000000 | 0.4231 | 0.2043 | 0.0750 | 0.0052 | 0.2339 | 0.0353 | 0.2519 | 0.1576 | 0.1589 | 0.1532 | 0.1364 | 0.2054 | 0.0885 | 0.1760 | 0.0390 | 0.1105 | 0.0150 | 0.0913 | 0.0015 | 0.0655 | 0.0000 | 0.0002 | 0.0004 | 0.0006 | 0.0016 | 0.0006 | 0.0084 | 0.0107 | 0.0408 | 0.0369 | 0.0753 | 0.0625 | 0.0404 | 0.0411 | 0.0677 | 0.0705 | 0.7654 | 0.7769 | 0.0002 | 0.0000 | 0.0009 | 0.0005 | 0.0016 | 0.0032 | 0.0125 | 0.0133 | 0.0519 | 0.0529 | 0.0775 | 0.0940 | 0.0542 | 0.0529 | 0.0860 | 0.0876 | 0.7152 | 0.6955 | 0.0002 | 0.0013 | 0.0024 | 0.0124 | 0.0425 | 0.0726 | 0.0494 | 0.0774 | 0.7419 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 755 | 233 | | 6882 | 11035 | 750.8 | 130.11 | 50.30 | 107.22 | 589 | 637 | 676 | 712 | 743 | 780 | 818 | 862 | 917 | 0.0847 | 935 | 0.936 | 120.35 | 37.05 | 2 | 0.0442 | 304 | 0.0010 | 30.30 | 7.224 | 0.2258 | 580634.0 | 462000000 | 378000000000 | 319000000000000 | 0.4407 | 0.2046 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0019 | 0.0001 | 0.0078 | 0.0003 | 0.0358 | 0.0142 | 0.0524 | 0.0228 | 0.0553 | 0.0152 | 0.0717 | 0.0231 | 0.7735 | 0.9243 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0031 | 0.0003 | 0.0186 | 0.0130 | 0.0277 | 0.0192 | 0.0279 | 0.0119 | 0.0379 | 0.0175 | 0.8843 | 0.9381 | 0.0012 | 0.0000 | 0.0048 | 0.0000 | 0.0203 | 0.0102 | 0.0501 | 0.1122 | 0.0776 | 0.0918 | 0.1241 | 0.1531 | 0.1181 | 0.1122 | 0.1050 | 0.1429 | 0.4988 | 0.3776 | 0.0009 | 0.0021 | 0.0039 | 0.0173 | 0.0318 | 0.0500 | 0.0518 | 0.0760 | 0.7662 | 7 | 9 | 11 | 12 | 15 | 19 | 26 | 42 | 126 | 0.0842 | 13.28 | 3.740 | 0.6597 | 14024.1 | 7570000 | 5380000000 | 4510000000000 | 0.4239 | 0.2208 | 0.0278 | 0.0089 | 0.0872 | 0.0149 | 0.1930 | 0.0343 | 0.1818 | 0.0961 | 0.1781 | 0.1586 | 0.1447 | 0.1571 | 0.1095 | 0.1400 | 0.0538 | 0.1482 | 0.0241 | 0.2420 | 0.0017 | 0.0034 | 0.0022 | 0.0044 | 0.0074 | 0.0065 | 0.0288 | 0.0266 | 0.0616 | 0.0536 | 0.0634 | 0.0615 | 0.0621 | 0.0663 | 0.0743 | 0.0844 | 0.6984 | 0.6933 | 0.0000 | 0.0013 | 0.0011 | 0.0013 | 0.0046 | 0.0019 | 0.0194 | 0.0183 | 0.0549 | 0.0593 | 0.0800 | 0.0732 | 0.0446 | 0.0511 | 0.0652 | 0.0650 | 0.7301 | 0.7287 | 0.0015 | 0.0025 | 0.0041 | 0.0259 | 0.0498 | 0.0747 | 0.0503 | 0.0711 | 0.7202 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 292 | 776 | | 6777 | 12524 | 325.6 | 51.91 | 172.85 | 222.30 | 258 | 277 | 296 | 311 | 323 | 337 | 352 | 369 | 393 | 0.0787 | 986 | 1.019 | 135.34 | 41.01 | 1 | 0.0484 | 328 | 0.0017 | 16.93 | 6.629 | 0.2646 | 108700.0 | 37200000 | 13000000000 | 4670000000000 | 0.3905 | 0.2545 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0036 | 0.0001 | 0.0131 | 0.0003 | 0.0300 | 0.0124 | 0.0571 | 0.0234 | 0.0742 | 0.0142 | 0.0991 | 0.0285 | 0.7210 | 0.9211 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0000 | 0.0071 | 0.0001 | 0.0167 | 0.0114 | 0.0295 | 0.0193 | 0.0326 | 0.0106 | 0.0443 | 0.0171 | 0.8660 | 0.9414 | 0.0057 | 0.0000 | 0.0114 | 0.0000 | 0.0341 | 0.0000 | 0.0994 | 0.0000 | 0.0994 | 0.0000 | 0.1605 | 0.0000 | 0.1179 | 0.0000 | 0.1264 | 0.0000 | 0.3452 | 0.0000 | 0.0015 | 0.0034 | 0.0073 | 0.0208 | 0.0531 | 0.0784 | 0.0815 | 0.1227 | 0.6313 | 14 | 16 | 19 | 25 | 51 | 113 | 215 | 343 | 515 | 0.0450 | 24.78 | 5.251 | 0.4914 | 79286.9 | 49200000 | 36500000000 | 31300000000000 | 0.4891 | 0.1521 | 0.0682 | 0.0006 | 0.2302 | 0.0144 | 0.3264 | 0.1428 | 0.1949 | 0.1888 | 0.1084 | 0.2199 | 0.0560 | 0.1929 | 0.0097 | 0.1180 | 0.0049 | 0.0760 | 0.0012 | 0.0466 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0015 | 0.0099 | 0.0101 | 0.0578 | 0.0482 | 0.0893 | 0.0778 | 0.0562 | 0.0523 | 0.0885 | 0.0782 | 0.6971 | 0.7317 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0023 | 0.0032 | 0.0138 | 0.0193 | 0.0706 | 0.0776 | 0.1115 | 0.1144 | 0.0701 | 0.0761 | 0.0996 | 0.1129 | 0.6310 | 0.5957 | 0.0000 | 0.0000 | 0.0012 | 0.0129 | 0.0628 | 0.1014 | 0.0584 | 0.0960 | 0.6673 |