High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1028 | 231 | | 11368 | 9358 | 393.3 | 133.58 | 93.30 | 136.68 | 187 | 274 | 336 | 383 | 422 | 451 | 481 | 509 | 544 | 0.1038 | 971 | 0.530 | 101.02 | 17.03 | 7 | 0.0223 | 254 | 0.0009 | 24.62 | 7.358 | 0.2464 | 172513.0 | 80400000 | 39000000000 | 19500000000000 | 0.5210 | 0.1387 | 0.0011 | 0.0006 | 0.0017 | 0.0005 | 0.0047 | 0.0018 | 0.0170 | 0.0049 | 0.0766 | 0.0277 | 0.1275 | 0.0545 | 0.1031 | 0.0384 | 0.1389 | 0.0594 | 0.5294 | 0.8122 | 0.0000 | 0.0001 | 0.0001 | 0.0001 | 0.0000 | 0.0002 | 0.0023 | 0.0012 | 0.0230 | 0.0184 | 0.0392 | 0.0346 | 0.0241 | 0.0188 | 0.0387 | 0.0285 | 0.8726 | 0.8980 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0061 | 0.0000 | 0.0163 | 0.0000 | 0.0472 | 0.0000 | 0.0674 | 0.0000 | 0.0653 | 0.0000 | 0.0888 | 0.0000 | 0.7054 | 1.0000 | 0.0003 | 0.0002 | 0.0009 | 0.0047 | 0.0314 | 0.0487 | 0.0382 | 0.0542 | 0.8214 | 10 | 12 | 15 | 20 | 34 | 52 | 79 | 150 | 276 | 0.1156 | 10.49 | 4.045 | 0.6216 | 27384.8 | 12500000 | 7130000000 | 4620000000000 | 0.4672 | 0.1594 | 0.0875 | 0.0139 | 0.2611 | 0.0541 | 0.2439 | 0.2073 | 0.1148 | 0.1314 | 0.0933 | 0.1294 | 0.0689 | 0.1208 | 0.0473 | 0.0812 | 0.0445 | 0.0759 | 0.0387 | 0.1861 | 0.0003 | 0.0020 | 0.0031 | 0.0022 | 0.0037 | 0.0053 | 0.0252 | 0.0193 | 0.0857 | 0.0735 | 0.1244 | 0.1092 | 0.0857 | 0.0732 | 0.1163 | 0.1151 | 0.5556 | 0.6003 | 0.0000 | 0.0000 | 0.0004 | 0.0010 | 0.0045 | 0.0077 | 0.0254 | 0.0305 | 0.0994 | 0.1056 | 0.1582 | 0.1608 | 0.0856 | 0.0944 | 0.1270 | 0.1370 | 0.4996 | 0.4630 | 0.0008 | 0.0044 | 0.0044 | 0.0252 | 0.0913 | 0.1442 | 0.0873 | 0.1197 | 0.5226 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 341 | 154 | | 3660 | 2741 | 145.1 | 40.32 | 362.39 | 193.78 | 100 | 113 | 122 | 131 | 139 | 148 | 158 | 173 | 199 | 0.1423 | 390 | 0.690 | 91.44 | 18.79 | 1 | 0.0628 | 230 | 0.0017 | 31.24 | 6.666 | 0.2130 | 22685.8 | 3840000 | 708000000 | 142000000000 | 0.4590 | 0.1971 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0099 | 0.0000 | 0.0292 | 0.0034 | 0.0887 | 0.0281 | 0.1651 | 0.0650 | 0.1547 | 0.0625 | 0.1731 | 0.0940 | 0.3774 | 0.7470 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0018 | 0.0000 | 0.0113 | 0.0020 | 0.0389 | 0.0146 | 0.0752 | 0.0346 | 0.0724 | 0.0242 | 0.0947 | 0.0466 | 0.7043 | 0.8781 | 0.0056 | 0.0031 | 0.0042 | 0.0061 | 0.0225 | 0.0429 | 0.0591 | 0.0982 | 0.1224 | 0.1595 | 0.1758 | 0.2178 | 0.1097 | 0.1012 | 0.1280 | 0.1380 | 0.3727 | 0.2331 | 0.0000 | 0.0056 | 0.0175 | 0.0437 | 0.0936 | 0.1392 | 0.1180 | 0.1311 | 0.4513 | 105 | 176 | 244 | 302 | 359 | 408 | 457 | 521 | 616 | 0.0007 | 113.79 | 7.416 | 0.1244 | 168859.0 | 91300000 | 54900000000 | 35900000000000 | 0.5411 | 0.1415 | 0.0040 | 0.0007 | 0.0464 | 0.0056 | 0.1300 | 0.0190 | 0.1950 | 0.0556 | 0.1963 | 0.0999 | 0.1817 | 0.1955 | 0.1300 | 0.1871 | 0.0756 | 0.1906 | 0.0411 | 0.2461 | 0.0000 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0049 | 0.0305 | 0.0148 | 0.0610 | 0.0473 | 0.1103 | 0.0976 | 0.1139 | 0.0867 | 0.1144 | 0.1114 | 0.5610 | 0.6358 | 0.0032 | 0.0082 | 0.0095 | 0.0148 | 0.0242 | 0.0346 | 0.0621 | 0.0824 | 0.1137 | 0.1466 | 0.1505 | 0.1928 | 0.1232 | 0.1285 | 0.1568 | 0.1450 | 0.3568 | 0.2471 | 0.0007 | 0.0015 | 0.0154 | 0.0308 | 0.0968 | 0.1357 | 0.1086 | 0.1519 | 0.4585 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1160 | 141 | | 3233 | 11358 | 59.9 | 15.14 | 124.51 | 201.52 | 40 | 47 | 52 | 56 | 59 | 63 | 68 | 73 | 80 | 0.0812 | 922 | 1.116 | 66.27 | 24.02 | 8 | 0.0520 | 168 | 0.0039 | 9.71 | 5.841 | 0.3283 | 3816.7 | 256199 | 18000000 | 1310000000 | 0.4210 | 0.2075 | 0.0016 | 0.0007 | 0.0121 | 0.0007 | 0.0236 | 0.0021 | 0.0356 | 0.0084 | 0.0773 | 0.0453 | 0.1135 | 0.0541 | 0.1321 | 0.0699 | 0.1908 | 0.1173 | 0.4134 | 0.7015 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0058 | 0.0007 | 0.0136 | 0.0046 | 0.0342 | 0.0320 | 0.0427 | 0.0346 | 0.0497 | 0.0369 | 0.0730 | 0.0515 | 0.7767 | 0.8398 | 0.0133 | 0.0415 | 0.0146 | 0.0553 | 0.0320 | 0.0968 | 0.0626 | 0.0829 | 0.0786 | 0.1613 | 0.1012 | 0.1705 | 0.1318 | 0.1475 | 0.1491 | 0.1521 | 0.4168 | 0.0922 | 0.0063 | 0.0101 | 0.0184 | 0.0380 | 0.0582 | 0.0671 | 0.0880 | 0.1063 | 0.6076 | 16 | 20 | 23 | 28 | 42 | 71 | 118 | 184 | 325 | 0.0815 | 10.02 | 4.228 | 0.6192 | 56109.0 | 50800000 | 64300000000 | 94700000000000 | 0.6731 | 0.0824 | 0.0382 | 0.0025 | 0.1393 | 0.0177 | 0.1670 | 0.0809 | 0.1460 | 0.1089 | 0.1651 | 0.1648 | 0.1431 | 0.1712 | 0.1002 | 0.1344 | 0.0716 | 0.1363 | 0.0296 | 0.1834 | 0.0000 | 0.0004 | 0.0018 | 0.0020 | 0.0063 | 0.0029 | 0.0266 | 0.0186 | 0.0673 | 0.0669 | 0.0986 | 0.0822 | 0.0819 | 0.0716 | 0.1122 | 0.1042 | 0.6054 | 0.6512 | 0.0004 | 0.0029 | 0.0043 | 0.0062 | 0.0093 | 0.0083 | 0.0377 | 0.0360 | 0.0890 | 0.0989 | 0.1328 | 0.1320 | 0.0800 | 0.0757 | 0.1120 | 0.1105 | 0.5345 | 0.5294 | 0.0012 | 0.0027 | 0.0067 | 0.0307 | 0.0828 | 0.1186 | 0.0791 | 0.1205 | 0.5577 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1049 | 270 | | 3875 | 7952 | 133.1 | 35.91 | 157.83 | 125.74 | 94 | 104 | 113 | 121 | 128 | 136 | 145 | 157 | 179 | 0.0832 | 662 | 0.854 | 78.82 | 25.55 | 2 | 0.0565 | 219 | 0.0020 | 26.25 | 6.494 | 0.2455 | 18997.6 | 2930000 | 490000000 | 89600000000 | 0.4209 | 0.2213 | 0.0000 | 0.0003 | 0.0004 | 0.0000 | 0.0074 | 0.0003 | 0.0302 | 0.0020 | 0.0944 | 0.0294 | 0.1627 | 0.0582 | 0.1605 | 0.0616 | 0.1828 | 0.0913 | 0.3616 | 0.7570 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0030 | 0.0000 | 0.0097 | 0.0003 | 0.0462 | 0.0196 | 0.0716 | 0.0346 | 0.0726 | 0.0291 | 0.1044 | 0.0471 | 0.6921 | 0.8694 | 0.0086 | 0.0097 | 0.0143 | 0.0065 | 0.0399 | 0.0259 | 0.0799 | 0.1003 | 0.1241 | 0.1586 | 0.1526 | 0.1715 | 0.0984 | 0.1100 | 0.1184 | 0.1683 | 0.3638 | 0.2492 | 0.0024 | 0.0083 | 0.0166 | 0.0391 | 0.1073 | 0.1375 | 0.1203 | 0.1316 | 0.4369 | 26 | 44 | 68 | 98 | 128 | 163 | 203 | 251 | 336 | 0.0035 | 41.32 | 6.588 | 0.3220 | 40720.6 | 13800000 | 5550000000 | 2540000000000 | 0.4558 | 0.2138 | 0.0196 | 0.0022 | 0.0713 | 0.0072 | 0.1578 | 0.0421 | 0.1767 | 0.0623 | 0.2000 | 0.1326 | 0.1804 | 0.1870 | 0.1084 | 0.1581 | 0.0531 | 0.1675 | 0.0327 | 0.2410 | 0.0012 | 0.0000 | 0.0015 | 0.0021 | 0.0055 | 0.0037 | 0.0159 | 0.0118 | 0.0585 | 0.0468 | 0.0938 | 0.0773 | 0.0774 | 0.0664 | 0.1074 | 0.0880 | 0.6388 | 0.7040 | 0.0008 | 0.0034 | 0.0053 | 0.0087 | 0.0120 | 0.0135 | 0.0361 | 0.0429 | 0.0847 | 0.1118 | 0.1295 | 0.1301 | 0.1043 | 0.1186 | 0.1401 | 0.1533 | 0.4872 | 0.4178 | 0.0006 | 0.0033 | 0.0108 | 0.0222 | 0.0752 | 0.1049 | 0.0869 | 0.1254 | 0.5707 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 262 | 293 | | 4620 | 9068 | 125.3 | 34.05 | 229.46 | 230.57 | 87 | 97 | 105 | 113 | 120 | 129 | 139 | 150 | 170 | 0.0786 | 713 | 0.960 | 89.94 | 24.74 | 1 | 0.0455 | 210 | 0.0019 | 28.55 | 6.554 | 0.2287 | 16849.6 | 2440000 | 379000000 | 63400000000 | 0.4415 | 0.2073 | 0.0011 | 0.0000 | 0.0034 | 0.0000 | 0.0134 | 0.0020 | 0.0550 | 0.0044 | 0.1237 | 0.0285 | 0.1753 | 0.0668 | 0.1760 | 0.0717 | 0.1955 | 0.1060 | 0.2566 | 0.7207 | 0.0003 | 0.0000 | 0.0014 | 0.0000 | 0.0025 | 0.0002 | 0.0129 | 0.0016 | 0.0525 | 0.0172 | 0.0784 | 0.0347 | 0.0865 | 0.0293 | 0.1231 | 0.0528 | 0.6423 | 0.8643 | 0.0053 | 0.0075 | 0.0149 | 0.0151 | 0.0351 | 0.0327 | 0.0904 | 0.1332 | 0.1521 | 0.2010 | 0.1883 | 0.2161 | 0.1223 | 0.1156 | 0.1383 | 0.1231 | 0.2532 | 0.1558 | 0.0024 | 0.0043 | 0.0097 | 0.0454 | 0.0985 | 0.1424 | 0.1318 | 0.1544 | 0.4112 | 25 | 41 | 69 | 102 | 141 | 203 | 283 | 398 | 568 | 0.0094 | 60.31 | 6.466 | 0.3430 | 105806.0 | 66900000 | 50200000000 | 42000000000000 | 0.4589 | 0.1675 | 0.0392 | 0.0005 | 0.1446 | 0.0095 | 0.2500 | 0.0695 | 0.1940 | 0.1304 | 0.1567 | 0.1823 | 0.1063 | 0.1972 | 0.0653 | 0.1403 | 0.0336 | 0.1173 | 0.0103 | 0.1530 | 0.0003 | 0.0002 | 0.0005 | 0.0022 | 0.0021 | 0.0028 | 0.0152 | 0.0130 | 0.0627 | 0.0430 | 0.0970 | 0.0745 | 0.0807 | 0.0682 | 0.1031 | 0.0917 | 0.6385 | 0.7043 | 0.0000 | 0.0004 | 0.0036 | 0.0013 | 0.0053 | 0.0101 | 0.0246 | 0.0331 | 0.0891 | 0.0947 | 0.1162 | 0.1404 | 0.1023 | 0.1086 | 0.1276 | 0.1379 | 0.5314 | 0.4736 | 0.0015 | 0.0024 | 0.0037 | 0.0198 | 0.0678 | 0.1110 | 0.0916 | 0.1199 | 0.5823 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 266 | 404 | | 2278 | 9177 | 440.8 | 82.93 | 18.18 | 14.33 | 329 | 363 | 393 | 419 | 442 | 462 | 484 | 509 | 554 | 0.0623 | 572 | 0.857 | 85.43 | 24.17 | 1 | 0.0979 | 223 | 0.0015 | 22.45 | 6.709 | 0.2343 | 201189.0 | 94800000 | 46100000000 | 23000000000000 | 0.3824 | 0.2567 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0045 | 0.0000 | 0.0102 | 0.0013 | 0.0447 | 0.0224 | 0.0735 | 0.0385 | 0.0671 | 0.0251 | 0.0927 | 0.0354 | 0.7073 | 0.8772 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0042 | 0.0004 | 0.0221 | 0.0184 | 0.0390 | 0.0347 | 0.0269 | 0.0158 | 0.0421 | 0.0237 | 0.8635 | 0.9069 | 0.0030 | 0.0222 | 0.0090 | 0.0000 | 0.0270 | 0.0889 | 0.0450 | 0.0889 | 0.0601 | 0.2000 | 0.1141 | 0.1333 | 0.1171 | 0.1778 | 0.1081 | 0.1333 | 0.5165 | 0.1556 | 0.0000 | 0.0009 | 0.0035 | 0.0130 | 0.0496 | 0.0696 | 0.0600 | 0.0904 | 0.7130 | 9 | 11 | 12 | 14 | 15 | 17 | 19 | 22 | 28 | 0.2118 | 0.79 | 1.993 | 0.8257 | 536.0 | 35898.2 | 4390000 | 666000000 | 0.5182 | 0.1416 | 0.0551 | 0.0050 | 0.0834 | 0.0121 | 0.1015 | 0.0296 | 0.1367 | 0.0539 | 0.1535 | 0.0819 | 0.1890 | 0.1115 | 0.1671 | 0.1301 | 0.0914 | 0.1928 | 0.0223 | 0.3829 | 0.0260 | 0.0018 | 0.0361 | 0.0067 | 0.0367 | 0.0183 | 0.0476 | 0.0364 | 0.0429 | 0.0592 | 0.0677 | 0.0813 | 0.0851 | 0.0830 | 0.1435 | 0.1084 | 0.5144 | 0.6048 | 0.0291 | 0.0429 | 0.0530 | 0.0429 | 0.0540 | 0.0429 | 0.0673 | 0.0648 | 0.0726 | 0.0843 | 0.1017 | 0.1199 | 0.0984 | 0.1240 | 0.1437 | 0.1337 | 0.3801 | 0.3444 | 0.0322 | 0.0313 | 0.0342 | 0.0453 | 0.0664 | 0.0914 | 0.1047 | 0.1395 | 0.4549 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 293 | 599 | | 8522 | 18731 | 124.8 | 36.07 | 159.94 | 131.22 | 85 | 96 | 104 | 111 | 119 | 128 | 138 | 151 | 171 | 0.0579 | 1085 | 0.655 | 121.63 | 30.46 | 3 | 0.0413 | 352 | 0.0021 | 21.46 | 6.543 | 0.2583 | 16874.9 | 2480000 | 397000000 | 69100000000 | 0.4218 | 0.2248 | 0.0015 | 0.0001 | 0.0032 | 0.0001 | 0.0107 | 0.0008 | 0.0379 | 0.0042 | 0.1011 | 0.0264 | 0.1598 | 0.0609 | 0.1590 | 0.0612 | 0.1920 | 0.0880 | 0.3347 | 0.7581 | 0.0008 | 0.0001 | 0.0009 | 0.0000 | 0.0028 | 0.0005 | 0.0110 | 0.0015 | 0.0388 | 0.0136 | 0.0711 | 0.0348 | 0.0644 | 0.0249 | 0.0950 | 0.0373 | 0.7152 | 0.8874 | 0.0062 | 0.0081 | 0.0090 | 0.0161 | 0.0225 | 0.0323 | 0.0749 | 0.0833 | 0.1256 | 0.1815 | 0.1532 | 0.1505 | 0.1256 | 0.1183 | 0.1369 | 0.1465 | 0.3459 | 0.2634 | 0.0016 | 0.0021 | 0.0083 | 0.0359 | 0.0826 | 0.1188 | 0.1038 | 0.1330 | 0.5139 | 17 | 35 | 65 | 98 | 134 | 170 | 212 | 264 | 339 | 0.0080 | 16.54 | 6.041 | 0.3804 | 42799.9 | 14800000 | 6050000000 | 2820000000000 | 0.4714 | 0.1684 | 0.0176 | 0.0010 | 0.0946 | 0.0066 | 0.2089 | 0.0387 | 0.1898 | 0.0857 | 0.1697 | 0.1579 | 0.1371 | 0.1913 | 0.0887 | 0.1635 | 0.0659 | 0.1531 | 0.0277 | 0.2022 | 0.0001 | 0.0001 | 0.0011 | 0.0005 | 0.0034 | 0.0022 | 0.0141 | 0.0087 | 0.0522 | 0.0394 | 0.0960 | 0.0745 | 0.0872 | 0.0648 | 0.1214 | 0.0920 | 0.6245 | 0.7178 | 0.0011 | 0.0016 | 0.0031 | 0.0070 | 0.0130 | 0.0169 | 0.0317 | 0.0396 | 0.0907 | 0.1065 | 0.1413 | 0.1568 | 0.1106 | 0.1168 | 0.1370 | 0.1456 | 0.4715 | 0.4093 | 0.0009 | 0.0021 | 0.0059 | 0.0218 | 0.0735 | 0.1242 | 0.1046 | 0.1292 | 0.5378 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1002 | 903 | | 2590 | 6854 | 671.8 | 130.82 | 57.85 | 118.91 | 504 | 556 | 597 | 632 | 666 | 700 | 730 | 773 | 852 | 0.0926 | 635 | 0.749 | 181.18 | 45.31 | 2 | 0.1853 | 480 | 0.0008 | 66.05 | 7.317 | 0.1448 | 468423.0 | 339000000 | 253000000000 | 195000000000000 | 0.4212 | 0.2260 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0004 | 0.0062 | 0.0020 | 0.0506 | 0.0208 | 0.1069 | 0.0425 | 0.0771 | 0.0261 | 0.1187 | 0.0357 | 0.6398 | 0.8725 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0032 | 0.0008 | 0.0272 | 0.0159 | 0.0614 | 0.0348 | 0.0378 | 0.0147 | 0.0591 | 0.0224 | 0.8113 | 0.9111 | 0.0051 | 0.0000 | 0.0000 | 0.0000 | 0.0103 | 0.0220 | 0.0282 | 0.0879 | 0.0872 | 0.1209 | 0.1385 | 0.1758 | 0.0923 | 0.1868 | 0.1256 | 0.1538 | 0.5128 | 0.2527 | 0.0008 | 0.0000 | 0.0040 | 0.0217 | 0.0593 | 0.1051 | 0.0842 | 0.1043 | 0.6207 | 10 | 12 | 13 | 16 | 22 | 33 | 42 | 64 | 129 | 0.1077 | 12.25 | 3.455 | 0.7303 | 17483.7 | 14800000 | 20400000000 | 35900000000000 | 0.6243 | 0.0943 | 0.0239 | 0.0079 | 0.0613 | 0.0126 | 0.0733 | 0.0238 | 0.1346 | 0.0516 | 0.1891 | 0.0827 | 0.1704 | 0.1263 | 0.1891 | 0.1468 | 0.1193 | 0.1640 | 0.0392 | 0.3843 | 0.0054 | 0.0046 | 0.0113 | 0.0057 | 0.0097 | 0.0092 | 0.0199 | 0.0218 | 0.0485 | 0.0402 | 0.0889 | 0.0766 | 0.0711 | 0.0808 | 0.0867 | 0.0938 | 0.6584 | 0.6673 | 0.0039 | 0.0018 | 0.0024 | 0.0027 | 0.0087 | 0.0064 | 0.0221 | 0.0282 | 0.0559 | 0.0645 | 0.1087 | 0.1064 | 0.0693 | 0.0709 | 0.0969 | 0.0982 | 0.6320 | 0.6209 | 0.0026 | 0.0066 | 0.0066 | 0.0178 | 0.0540 | 0.0949 | 0.0639 | 0.0988 | 0.6548 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1173 | 230 | | 893 | 1587 | 58.0 | 13.43 | 491.67 | 350.26 | 39 | 45 | 50 | 54 | 59 | 63 | 67 | 71 | 75 | 0.1878 | 298 | 1.216 | 22.85 | 8.25 | 1 | 0.0694 | 62 | 0.0063 | 5.77 | 5.275 | 0.3973 | 3548.7 | 226676 | 15000000 | 1020000000 | 0.4245 | 0.2042 | 0.0041 | 0.0000 | 0.0104 | 0.0000 | 0.0228 | 0.0012 | 0.0352 | 0.0119 | 0.1056 | 0.0380 | 0.1201 | 0.0403 | 0.1677 | 0.0712 | 0.1822 | 0.0830 | 0.3520 | 0.7544 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0058 | 0.0012 | 0.0159 | 0.0116 | 0.0418 | 0.0359 | 0.0390 | 0.0348 | 0.0592 | 0.0475 | 0.0649 | 0.0487 | 0.7706 | 0.8204 | 0.0095 | 0.0500 | 0.0143 | 0.1000 | 0.0190 | 0.0500 | 0.0476 | 0.2000 | 0.1381 | 0.3000 | 0.1095 | 0.1000 | 0.1810 | 0.0000 | 0.1905 | 0.2000 | 0.2905 | 0.0000 | 0.0043 | 0.0151 | 0.0151 | 0.0129 | 0.0430 | 0.0688 | 0.0860 | 0.1011 | 0.6538 | 107 | 162 | 233 | 315 | 418 | 517 | 636 | 803 | 998 | 0.0021 | 39.34 | 6.548 | 0.2363 | 364349.0 | 335000000 | 350000000000 | 398000000000000 | 0.5161 | 0.1411 | 0.0070 | 0.0000 | 0.0702 | 0.0035 | 0.1579 | 0.0228 | 0.2316 | 0.0683 | 0.2140 | 0.1278 | 0.1789 | 0.2277 | 0.0877 | 0.1611 | 0.0386 | 0.1664 | 0.0140 | 0.2224 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0061 | 0.0020 | 0.0255 | 0.0201 | 0.0522 | 0.0413 | 0.0765 | 0.0554 | 0.0667 | 0.0564 | 0.1129 | 0.0816 | 0.6590 | 0.7432 | 0.0019 | 0.0000 | 0.0000 | 0.0047 | 0.0111 | 0.0213 | 0.0390 | 0.0332 | 0.0686 | 0.0900 | 0.1317 | 0.1232 | 0.0891 | 0.0853 | 0.1132 | 0.1422 | 0.5455 | 0.5000 | 0.0000 | 0.0059 | 0.0089 | 0.0341 | 0.0548 | 0.0904 | 0.0919 | 0.1407 | 0.5733 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 176 | 439 | | 2149 | 10252 | 192.6 | 59.91 | 8.87 | 3.44 | 120 | 133 | 148 | 165 | 184 | 205 | 228 | 254 | 283 | 0.0694 | 712 | 0.822 | 57.98 | 20.03 | 1 | 0.0814 | 175 | 0.0084 | 2.12 | 4.986 | 0.5414 | 40700.9 | 9310000 | 2270000000 | 578000000000 | 0.3740 | 0.2645 | 0.0013 | 0.0012 | 0.0076 | 0.0030 | 0.0076 | 0.0041 | 0.0278 | 0.0100 | 0.0682 | 0.0349 | 0.1174 | 0.0573 | 0.1023 | 0.0473 | 0.1452 | 0.0810 | 0.5227 | 0.7612 | 0.0000 | 0.0010 | 0.0043 | 0.0020 | 0.0021 | 0.0030 | 0.0100 | 0.0070 | 0.0242 | 0.0214 | 0.0356 | 0.0349 | 0.0342 | 0.0244 | 0.0456 | 0.0449 | 0.8439 | 0.8614 | 0.0000 | 0.0064 | 0.0000 | 0.0032 | 0.0065 | 0.0127 | 0.0196 | 0.0255 | 0.0344 | 0.0541 | 0.0687 | 0.0637 | 0.0507 | 0.0732 | 0.0589 | 0.0669 | 0.7610 | 0.6943 | 0.0000 | 0.0000 | 0.0072 | 0.0196 | 0.0319 | 0.0330 | 0.0484 | 0.0649 | 0.7951 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 11 | 13 | 0.0123 | 12.27 | 4.870 | 0.3144 | 90.5 | 1065.26 | 14510.9 | 227463 | 0.4586 | 0.1831 | 0.0295 | 0.0009 | 0.1028 | 0.0024 | 0.1962 | 0.0094 | 0.2565 | 0.0319 | 0.2244 | 0.0719 | 0.1268 | 0.1660 | 0.0511 | 0.2677 | 0.0112 | 0.2954 | 0.0016 | 0.1543 | 0.0050 | 0.0000 | 0.0247 | 0.0004 | 0.0691 | 0.0026 | 0.1247 | 0.0146 | 0.1520 | 0.0414 | 0.1628 | 0.1000 | 0.1487 | 0.1803 | 0.1348 | 0.2780 | 0.1782 | 0.3828 | 0.1256 | 0.1981 | 0.1426 | 0.1338 | 0.1343 | 0.1060 | 0.1181 | 0.0730 | 0.1121 | 0.0782 | 0.0895 | 0.0773 | 0.0642 | 0.0695 | 0.0701 | 0.0712 | 0.1434 | 0.1929 | 0.0242 | 0.0702 | 0.1099 | 0.1423 | 0.1381 | 0.1306 | 0.1204 | 0.1069 | 0.1574 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1046 | 281 | | 697 | 6737 | 49.7 | 11.06 | 107.38 | 98.61 | 35 | 40 | 43 | 46 | 49 | 53 | 56 | 60 | 66 | 0.0687 | 463 | 0.653 | 94.02 | 20.03 | 1 | 0.3989 | 278 | 0.0147 | 2.37 | 4.400 | 0.5020 | 2589.0 | 140960 | 7970000 | 466000000 | 0.3646 | 0.2679 | 0.0024 | 0.0000 | 0.0049 | 0.0000 | 0.0147 | 0.0015 | 0.0293 | 0.0122 | 0.0880 | 0.0518 | 0.1174 | 0.0487 | 0.1418 | 0.0700 | 0.2103 | 0.1035 | 0.3912 | 0.7123 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0179 | 0.0088 | 0.0448 | 0.0423 | 0.0448 | 0.0350 | 0.0538 | 0.0482 | 0.0878 | 0.0496 | 0.7437 | 0.8161 | 0.0000 | 0.0714 | 0.0067 | 0.0714 | 0.0537 | 0.1071 | 0.0604 | 0.2143 | 0.0940 | 0.1429 | 0.0872 | 0.1429 | 0.0940 | 0.2500 | 0.1678 | 0.0000 | 0.4362 | 0.0000 | 0.0000 | 0.0087 | 0.0029 | 0.0320 | 0.0552 | 0.0698 | 0.0756 | 0.1105 | 0.6453 | 16 | 26 | 41 | 57 | 78 | 101 | 132 | 173 | 239 | 0.0142 | 10.47 | 5.299 | 0.4760 | 21253.2 | 5970000 | 2090000000 | 847000000000 | 0.5145 | 0.1485 | 0.0252 | 0.0015 | 0.0572 | 0.0053 | 0.1725 | 0.0393 | 0.1812 | 0.0766 | 0.1764 | 0.1392 | 0.1764 | 0.1702 | 0.1066 | 0.1387 | 0.0640 | 0.1528 | 0.0407 | 0.2764 | 0.0006 | 0.0003 | 0.0013 | 0.0016 | 0.0064 | 0.0045 | 0.0186 | 0.0143 | 0.0578 | 0.0428 | 0.0902 | 0.0659 | 0.0876 | 0.0653 | 0.1139 | 0.0900 | 0.6236 | 0.7153 | 0.0010 | 0.0023 | 0.0048 | 0.0053 | 0.0120 | 0.0164 | 0.0307 | 0.0282 | 0.0801 | 0.0921 | 0.1243 | 0.1268 | 0.0998 | 0.1009 | 0.1166 | 0.1291 | 0.5307 | 0.4988 | 0.0004 | 0.0020 | 0.0086 | 0.0207 | 0.0718 | 0.1128 | 0.0910 | 0.1175 | 0.5752 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 705 | 656 | | 2086 | 7084 | 755.3 | 409.67 | 4.68 | 2.47 | 169 | 264 | 426 | 649 | 862 | 982 | 1060 | 1141 | 1240 | 0.0841 | 596 | 0.902 | 85.38 | 22.85 | 2 | 0.1112 | 232 | 0.0008 | 88.53 | 7.287 | 0.1150 | 738249.0 | 798000000 | 907000000000 | 1.07E+15 | 0.3090 | 0.2823 | 0.0000 | 0.0000 | 0.0167 | 0.0013 | 0.0167 | 0.0013 | 0.0733 | 0.0088 | 0.3067 | 0.1107 | 0.2867 | 0.1723 | 0.1300 | 0.1233 | 0.1300 | 0.1849 | 0.0400 | 0.3975 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0264 | 0.0280 | 0.0380 | 0.0350 | 0.0233 | 0.0224 | 0.0396 | 0.0378 | 0.8712 | 0.8768 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0016 | 0.0030 | 0.0174 | 0.0324 | 0.0757 | 0.0576 | 0.1372 | 0.0536 | 0.0931 | 0.0890 | 0.1483 | 0.7634 | 0.5268 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0328 | 0.0345 | 0.0276 | 0.0405 | 0.8638 | 2 | 3 | 3 | 4 | 4 | 5 | 6 | 7 | 8 | 0.0353 | 0.22 | 0.723 | 0.2177 | 28.0 | 197.373 | 1573.42 | 13861.8 | 0.4480 | 0.1854 | 0.0919 | 0.0083 | 0.1989 | 0.0206 | 0.2527 | 0.0511 | 0.2301 | 0.0975 | 0.1382 | 0.1832 | 0.0656 | 0.2464 | 0.0204 | 0.2343 | 0.0022 | 0.1254 | 0.0000 | 0.0331 | 0.0082 | 0.0009 | 0.0316 | 0.0026 | 0.0687 | 0.0139 | 0.0919 | 0.0357 | 0.1178 | 0.0764 | 0.1357 | 0.1283 | 0.1428 | 0.1664 | 0.1753 | 0.2158 | 0.2280 | 0.3601 | 0.0631 | 0.0852 | 0.0954 | 0.1085 | 0.0927 | 0.1085 | 0.0907 | 0.1143 | 0.1286 | 0.1214 | 0.1226 | 0.1375 | 0.1302 | 0.1336 | 0.1434 | 0.0943 | 0.1334 | 0.0968 | 0.0278 | 0.0633 | 0.1001 | 0.0986 | 0.1143 | 0.1134 | 0.1331 | 0.1597 | 0.1898 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 218 | 312 | | 2655 | 8245 | 132.8 | 44.21 | 178.73 | 118.36 | 91 | 99 | 108 | 117 | 125 | 134 | 142 | 155 | 176 | 0.0813 | 670 | 0.683 | 79.32 | 27.66 | 1 | 0.0968 | 257 | 0.0031 | 18.62 | 6.095 | 0.3246 | 19582.2 | 3340000 | 689000000 | 173000000000 | 0.4385 | 0.1979 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0062 | 0.0004 | 0.0256 | 0.0020 | 0.0622 | 0.0283 | 0.1119 | 0.0557 | 0.1140 | 0.0414 | 0.1298 | 0.0602 | 0.5497 | 0.8120 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0037 | 0.0004 | 0.0115 | 0.0015 | 0.0314 | 0.0216 | 0.0492 | 0.0352 | 0.0413 | 0.0250 | 0.0581 | 0.0367 | 0.8043 | 0.8796 | 0.0043 | 0.0000 | 0.0065 | 0.0100 | 0.0151 | 0.0100 | 0.0454 | 0.0350 | 0.1080 | 0.1100 | 0.1058 | 0.1600 | 0.0778 | 0.0750 | 0.1231 | 0.1350 | 0.5140 | 0.4650 | 0.0027 | 0.0018 | 0.0100 | 0.0255 | 0.0656 | 0.0974 | 0.0792 | 0.1193 | 0.5984 | 59 | 76 | 93 | 115 | 144 | 182 | 225 | 275 | 351 | 0.0020 | 52.90 | 6.928 | 0.2551 | 45949.6 | 15000000 | 5740000000 | 2430000000000 | 0.5074 | 0.1593 | 0.0155 | 0.0010 | 0.0882 | 0.0092 | 0.2007 | 0.0209 | 0.1771 | 0.0654 | 0.1630 | 0.1485 | 0.1441 | 0.1660 | 0.0774 | 0.1622 | 0.0566 | 0.1523 | 0.0774 | 0.2745 | 0.0005 | 0.0002 | 0.0027 | 0.0019 | 0.0060 | 0.0044 | 0.0169 | 0.0095 | 0.0638 | 0.0525 | 0.1051 | 0.0712 | 0.0744 | 0.0711 | 0.1097 | 0.0969 | 0.6210 | 0.6922 | 0.0011 | 0.0039 | 0.0068 | 0.0123 | 0.0139 | 0.0178 | 0.0444 | 0.0468 | 0.0889 | 0.0868 | 0.1213 | 0.1391 | 0.0998 | 0.1297 | 0.1348 | 0.1440 | 0.4889 | 0.4196 | 0.0009 | 0.0036 | 0.0083 | 0.0238 | 0.0753 | 0.1202 | 0.0940 | 0.1196 | 0.5542 | ||
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1078 | 523 | | 14942 | 30535 | 213.6 | 65.41 | 182.99 | 225.98 | 137 | 159 | 176 | 193 | 208 | 224 | 242 | 265 | 299 | 0.0495 | 1511 | 0.501 | 139.13 | 33.29 | 9 | 0.0285 | 426 | 0.0011 | 32.46 | 7.146 | 0.2116 | 49882.5 | 12600000 | 3430000000 | 996000000000 | 0.4707 | 0.1872 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0114 | 0.0010 | 0.0396 | 0.0054 | 0.1050 | 0.0284 | 0.1755 | 0.0659 | 0.1723 | 0.0644 | 0.1742 | 0.0921 | 0.3187 | 0.7427 | 0.0005 | 0.0000 | 0.0007 | 0.0001 | 0.0015 | 0.0002 | 0.0105 | 0.0022 | 0.0389 | 0.0148 | 0.0680 | 0.0352 | 0.0666 | 0.0291 | 0.0852 | 0.0452 | 0.7281 | 0.8731 | 0.0023 | 0.0054 | 0.0057 | 0.0075 | 0.0154 | 0.0299 | 0.0570 | 0.0680 | 0.1115 | 0.1497 | 0.1591 | 0.1844 | 0.1081 | 0.1163 | 0.1420 | 0.1306 | 0.3989 | 0.3082 | 0.0007 | 0.0032 | 0.0068 | 0.0241 | 0.0727 | 0.1106 | 0.0894 | 0.1272 | 0.5653 | 7 | 9 | 13 | 25 | 64 | 146 | 254 | 375 | 525 | 0.0542 | 24.53 | 5.282 | 0.4416 | 84546.7 | 50200000 | 34700000000 | 26800000000000 | 0.4917 | 0.1628 | 0.0917 | 0.0009 | 0.2762 | 0.0235 | 0.3457 | 0.2055 | 0.1342 | 0.1964 | 0.0753 | 0.2196 | 0.0473 | 0.1648 | 0.0208 | 0.0975 | 0.0068 | 0.0592 | 0.0019 | 0.0325 | 0.0001 | 0.0000 | 0.0004 | 0.0004 | 0.0005 | 0.0007 | 0.0084 | 0.0060 | 0.0544 | 0.0468 | 0.0935 | 0.0840 | 0.0596 | 0.0515 | 0.0953 | 0.0815 | 0.6877 | 0.7291 | 0.0001 | 0.0001 | 0.0001 | 0.0004 | 0.0013 | 0.0016 | 0.0121 | 0.0199 | 0.0750 | 0.0811 | 0.1193 | 0.1295 | 0.0741 | 0.0859 | 0.1155 | 0.1244 | 0.6026 | 0.5571 | 0.0002 | 0.0002 | 0.0006 | 0.0101 | 0.0639 | 0.1058 | 0.0698 | 0.1080 | 0.6414 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 897 | 352 | | 491 | 10165 | 31.2 | 10.66 | 5.57 | 2.04 | 21 | 23 | 24 | 26 | 27 | 30 | 34 | 40 | 49 | 0.0858 | 872 | 0.813 | 87.21 | 20.59 | 5 | 0.4073 | 200 | 0.0618 | 0.76 | 3.150 | 0.6872 | 1083.9 | 42132.6 | 1810000 | 83600000 | 0.3481 | 0.2731 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0187 | 0.0025 | 0.0561 | 0.0150 | 0.1168 | 0.0848 | 0.2336 | 0.0798 | 0.1963 | 0.0873 | 0.1869 | 0.1446 | 0.1729 | 0.5860 | 0.0061 | 0.0000 | 0.0061 | 0.0000 | 0.0122 | 0.0021 | 0.0334 | 0.0125 | 0.0608 | 0.0582 | 0.0912 | 0.0353 | 0.0821 | 0.0561 | 0.1003 | 0.0811 | 0.6079 | 0.7547 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0348 | 0.0625 | 0.0609 | 0.0500 | 0.1391 | 0.1625 | 0.0609 | 0.1125 | 0.1043 | 0.0750 | 0.6000 | 0.5375 | 0.0000 | 0.0107 | 0.0000 | 0.0481 | 0.0428 | 0.1070 | 0.0695 | 0.1016 | 0.6203 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0061 | 0.11 | 0.381 | 0.0699 | 35.2 | 247.481 | 1925.98 | 16644.2 | 0.5163 | 0.1494 | 0.0075 | 0.0004 | 0.0317 | 0.0014 | 0.1096 | 0.0083 | 0.1889 | 0.0233 | 0.2557 | 0.0515 | 0.2310 | 0.1180 | 0.1247 | 0.2326 | 0.0447 | 0.3477 | 0.0060 | 0.2168 | 0.0016 | 0.0000 | 0.0075 | 0.0002 | 0.0348 | 0.0045 | 0.0908 | 0.0154 | 0.1571 | 0.0325 | 0.2323 | 0.0692 | 0.2275 | 0.1499 | 0.1597 | 0.3269 | 0.0887 | 0.4014 | 0.2469 | 0.4372 | 0.2984 | 0.2271 | 0.1850 | 0.0804 | 0.0888 | 0.0635 | 0.0564 | 0.0536 | 0.0355 | 0.0409 | 0.0392 | 0.0381 | 0.0282 | 0.0381 | 0.0214 | 0.0212 | 0.0197 | 0.0760 | 0.1532 | 0.2101 | 0.1844 | 0.1602 | 0.1001 | 0.0600 | 0.0363 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 617 | 741 | | 9928 | 9082 | 316.0 | 86.06 | 173.78 | 141.29 | 208 | 240 | 266 | 289 | 311 | 334 | 358 | 388 | 431 | 0.1070 | 972 | 1.101 | 126.49 | 42.11 | 1 | 0.0306 | 304 | 0.0003 | 132.65 | 8.162 | 0.1061 | 107236.0 | 38800000 | 14800000000 | 5960000000000 | 0.4826 | 0.1778 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0107 | 0.0001 | 0.0379 | 0.0016 | 0.1130 | 0.0261 | 0.1926 | 0.0663 | 0.1636 | 0.0767 | 0.1676 | 0.1002 | 0.3147 | 0.7290 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0065 | 0.0006 | 0.0383 | 0.0157 | 0.0809 | 0.0357 | 0.0693 | 0.0321 | 0.0909 | 0.0473 | 0.7140 | 0.8686 | 0.0031 | 0.0012 | 0.0040 | 0.0112 | 0.0058 | 0.0423 | 0.0590 | 0.1270 | 0.1709 | 0.2067 | 0.1789 | 0.1806 | 0.1079 | 0.1071 | 0.1514 | 0.1345 | 0.3191 | 0.1893 | 0.0000 | 0.0013 | 0.0023 | 0.0190 | 0.0877 | 0.1367 | 0.1063 | 0.1354 | 0.5113 | 20 | 36 | 65 | 103 | 143 | 189 | 238 | 298 | 377 | 0.0070 | 34.03 | 6.359 | 0.3017 | 50160.7 | 18200000 | 7670000000 | 3630000000000 | 0.5655 | 0.1272 | 0.0383 | 0.0004 | 0.1678 | 0.0090 | 0.2690 | 0.0860 | 0.1670 | 0.1530 | 0.1338 | 0.1699 | 0.1077 | 0.2023 | 0.0600 | 0.1264 | 0.0304 | 0.1210 | 0.0260 | 0.1321 | 0.0002 | 0.0000 | 0.0002 | 0.0002 | 0.0032 | 0.0011 | 0.0134 | 0.0098 | 0.0646 | 0.0510 | 0.1245 | 0.0968 | 0.0862 | 0.0748 | 0.1433 | 0.1256 | 0.5643 | 0.6408 | 0.0015 | 0.0008 | 0.0012 | 0.0011 | 0.0071 | 0.0072 | 0.0253 | 0.0459 | 0.1085 | 0.1206 | 0.1520 | 0.1714 | 0.1027 | 0.1251 | 0.1640 | 0.1524 | 0.4377 | 0.3754 | 0.0003 | 0.0003 | 0.0053 | 0.0204 | 0.0876 | 0.1385 | 0.1010 | 0.1491 | 0.4976 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1179 | 189 | | 16382 | 26563 | 119.9 | 50.77 | 96.33 | 96.08 | 57 | 80 | 93 | 105 | 115 | 128 | 142 | 159 | 186 | 0.0652 | 1732 | 0.279 | 134.45 | 18.44 | 8 | 0.0245 | 401 | 0.0012 | 34.16 | 7.111 | 0.2279 | 16954.2 | 2720000 | 485000000 | 94900000000 | 0.4885 | 0.1704 | 0.0014 | 0.0001 | 0.0069 | 0.0005 | 0.0266 | 0.0024 | 0.0715 | 0.0104 | 0.1597 | 0.0480 | 0.2113 | 0.0993 | 0.1753 | 0.1092 | 0.1597 | 0.1428 | 0.1876 | 0.5873 | 0.0004 | 0.0001 | 0.0017 | 0.0003 | 0.0033 | 0.0012 | 0.0102 | 0.0037 | 0.0386 | 0.0208 | 0.0699 | 0.0357 | 0.0674 | 0.0386 | 0.0962 | 0.0530 | 0.7123 | 0.8467 | 0.0017 | 0.0038 | 0.0051 | 0.0091 | 0.0110 | 0.0152 | 0.0442 | 0.0800 | 0.1188 | 0.1523 | 0.1512 | 0.1789 | 0.1184 | 0.1144 | 0.1491 | 0.1413 | 0.4006 | 0.3050 | 0.0009 | 0.0013 | 0.0058 | 0.0245 | 0.0728 | 0.1185 | 0.1037 | 0.1302 | 0.5422 | 15 | 22 | 32 | 46 | 64 | 86 | 117 | 158 | 222 | 0.0165 | 11.29 | 5.277 | 0.4716 | 18511.3 | 5390000 | 2090000000 | 994000000000 | 0.5640 | 0.1104 | 0.0416 | 0.0021 | 0.1298 | 0.0145 | 0.2417 | 0.0717 | 0.1786 | 0.1322 | 0.1563 | 0.1705 | 0.1056 | 0.1818 | 0.0805 | 0.1400 | 0.0452 | 0.1272 | 0.0207 | 0.1600 | 0.0013 | 0.0006 | 0.0026 | 0.0025 | 0.0052 | 0.0043 | 0.0226 | 0.0158 | 0.0717 | 0.0537 | 0.1141 | 0.0969 | 0.0904 | 0.0786 | 0.1320 | 0.1170 | 0.5601 | 0.6307 | 0.0017 | 0.0015 | 0.0030 | 0.0031 | 0.0089 | 0.0133 | 0.0324 | 0.0402 | 0.0970 | 0.1132 | 0.1484 | 0.1592 | 0.1051 | 0.1113 | 0.1413 | 0.1490 | 0.4622 | 0.4093 | 0.0015 | 0.0038 | 0.0079 | 0.0238 | 0.0829 | 0.1287 | 0.1026 | 0.1362 | 0.5125 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1158 | 547 | | 3628 | 6182 | 70.1 | 18.21 | 293.38 | 247.61 | 48 | 56 | 61 | 65 | 68 | 73 | 77 | 84 | 93 | 0.1234 | 763 | 0.764 | 96.33 | 26.17 | 2 | 0.0714 | 259 | 0.0063 | 7.41 | 5.408 | 0.3836 | 5245.5 | 419586 | 36100000 | 3360000000 | 0.4909 | 0.1773 | 0.0023 | 0.0000 | 0.0055 | 0.0006 | 0.0137 | 0.0022 | 0.0339 | 0.0099 | 0.0870 | 0.0304 | 0.1612 | 0.0565 | 0.1658 | 0.0624 | 0.1557 | 0.1052 | 0.3750 | 0.7327 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0021 | 0.0006 | 0.0086 | 0.0049 | 0.0429 | 0.0204 | 0.0689 | 0.0357 | 0.0703 | 0.0319 | 0.0998 | 0.0512 | 0.7071 | 0.8550 | 0.0014 | 0.0156 | 0.0205 | 0.0156 | 0.0533 | 0.1172 | 0.0861 | 0.1367 | 0.1516 | 0.1797 | 0.1954 | 0.1680 | 0.1175 | 0.1016 | 0.1434 | 0.0977 | 0.2309 | 0.1680 | 0.0029 | 0.0041 | 0.0140 | 0.0479 | 0.0918 | 0.1350 | 0.1227 | 0.1508 | 0.4307 | 31 | 70 | 122 | 175 | 230 | 293 | 376 | 483 | 655 | 0.0026 | 110.17 | 7.306 | 0.2160 | 147376.0 | 96400000 | 74100000000 | 63400000000000 | 0.5179 | 0.1541 | 0.0174 | 0.0019 | 0.0872 | 0.0087 | 0.1851 | 0.0367 | 0.1986 | 0.0783 | 0.1928 | 0.1522 | 0.1415 | 0.2011 | 0.0688 | 0.1609 | 0.0736 | 0.1542 | 0.0349 | 0.2059 | 0.0013 | 0.0005 | 0.0023 | 0.0022 | 0.0085 | 0.0027 | 0.0214 | 0.0121 | 0.0628 | 0.0486 | 0.0986 | 0.0955 | 0.0832 | 0.0720 | 0.1216 | 0.1055 | 0.6003 | 0.6608 | 0.0015 | 0.0037 | 0.0040 | 0.0086 | 0.0119 | 0.0165 | 0.0308 | 0.0354 | 0.0826 | 0.0886 | 0.1323 | 0.1405 | 0.0930 | 0.1069 | 0.1264 | 0.1497 | 0.5174 | 0.4502 | 0.0012 | 0.0016 | 0.0113 | 0.0311 | 0.0638 | 0.1179 | 0.0973 | 0.1179 | 0.5579 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 815 | 163 | | 2938 | 15825 | 562.8 | 165.66 | 10.78 | 7.31 | 288 | 401 | 494 | 571 | 620 | 652 | 677 | 696 | 723 | 0.0577 | 913 | 0.956 | 43.93 | 14.04 | 1 | 0.0388 | 114 | 0.0035 | 13.77 | 6.195 | 0.3459 | 344227.0 | 221000000 | 147000000000 | 100000000000000 | 0.3768 | 0.2427 | 0.0046 | 0.0000 | 0.0069 | 0.0000 | 0.0069 | 0.0004 | 0.0299 | 0.0021 | 0.0851 | 0.0207 | 0.1219 | 0.0435 | 0.0913 | 0.0236 | 0.1296 | 0.0464 | 0.5238 | 0.8632 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0016 | 0.0213 | 0.0175 | 0.0344 | 0.0358 | 0.0222 | 0.0179 | 0.0376 | 0.0350 | 0.8822 | 0.8921 | 0.0022 | 0.0000 | 0.0078 | 0.0100 | 0.0111 | 0.0200 | 0.0388 | 0.0200 | 0.0543 | 0.0800 | 0.1008 | 0.1300 | 0.1008 | 0.0700 | 0.1274 | 0.1400 | 0.5570 | 0.5300 | 0.0006 | 0.0000 | 0.0000 | 0.0050 | 0.0233 | 0.0417 | 0.0267 | 0.0389 | 0.8639 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 19 | 0.2362 | 0.38 | 1.298 | 0.6613 | 169.5 | 3950.18 | 122472 | 4500000 | 0.5976 | 0.1040 | 0.0323 | 0.0020 | 0.0756 | 0.0106 | 0.1133 | 0.0336 | 0.1438 | 0.0726 | 0.1811 | 0.1062 | 0.1857 | 0.1514 | 0.1597 | 0.2027 | 0.0873 | 0.2334 | 0.0211 | 0.1876 | 0.0202 | 0.0012 | 0.0489 | 0.0067 | 0.0693 | 0.0257 | 0.0868 | 0.0568 | 0.1051 | 0.0848 | 0.1135 | 0.1256 | 0.1228 | 0.1539 | 0.1364 | 0.1840 | 0.2969 | 0.3614 | 0.0929 | 0.0470 | 0.0631 | 0.0212 | 0.0423 | 0.0131 | 0.0317 | 0.0217 | 0.0372 | 0.0359 | 0.0533 | 0.0606 | 0.0451 | 0.0526 | 0.0776 | 0.0773 | 0.5568 | 0.6705 | 0.0675 | 0.0951 | 0.0928 | 0.0982 | 0.0980 | 0.0940 | 0.0648 | 0.0545 | 0.3351 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 948 | 93 | | 6191 | 5411 | 97.2 | 28.78 | 176.56 | 250.57 | 65 | 74 | 81 | 88 | 94 | 101 | 108 | 118 | 134 | 0.1785 | 966 | 0.915 | 160.59 | 50.92 | 3 | 0.0728 | 451 | 0.0012 | 44.43 | 7.019 | 0.1810 | 10281.0 | 1180000 | 147000000 | 20000000000 | 0.4296 | 0.2140 | 0.0006 | 0.0000 | 0.0021 | 0.0000 | 0.0200 | 0.0011 | 0.0445 | 0.0080 | 0.1179 | 0.0337 | 0.1765 | 0.0649 | 0.1815 | 0.0792 | 0.1824 | 0.1193 | 0.2744 | 0.6938 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0003 | 0.0120 | 0.0043 | 0.0482 | 0.0193 | 0.0816 | 0.0358 | 0.0819 | 0.0379 | 0.1103 | 0.0573 | 0.6632 | 0.8451 | 0.0046 | 0.0144 | 0.0144 | 0.0341 | 0.0311 | 0.0485 | 0.0971 | 0.0987 | 0.1115 | 0.1813 | 0.1624 | 0.1418 | 0.1252 | 0.0987 | 0.1373 | 0.1275 | 0.3164 | 0.2549 | 0.0028 | 0.0059 | 0.0121 | 0.0385 | 0.0905 | 0.1273 | 0.1099 | 0.1328 | 0.4802 | 19 | 24 | 31 | 44 | 66 | 104 | 177 | 282 | 478 | 0.0405 | 26.68 | 4.951 | 0.5100 | 93949.7 | 80000000 | 85800000000 | 105000000000000 | 0.6057 | 0.0948 | 0.1074 | 0.0033 | 0.2729 | 0.0546 | 0.2550 | 0.2116 | 0.1208 | 0.1860 | 0.1230 | 0.1815 | 0.0582 | 0.1503 | 0.0425 | 0.0846 | 0.0201 | 0.0579 | 0.0000 | 0.0702 | 0.0005 | 0.0005 | 0.0043 | 0.0019 | 0.0086 | 0.0075 | 0.0311 | 0.0230 | 0.1063 | 0.0962 | 0.1283 | 0.1304 | 0.1063 | 0.0863 | 0.1546 | 0.1487 | 0.4600 | 0.5056 | 0.0007 | 0.0016 | 0.0071 | 0.0049 | 0.0127 | 0.0138 | 0.0438 | 0.0454 | 0.1243 | 0.1410 | 0.1653 | 0.1896 | 0.1165 | 0.1135 | 0.1645 | 0.1564 | 0.3651 | 0.3339 | 0.0018 | 0.0037 | 0.0098 | 0.0331 | 0.1227 | 0.1466 | 0.1110 | 0.1724 | 0.3988 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 779 | 488 | | 1658 | 7515 | 661.2 | 127.45 | 21.12 | 72.35 | 472 | 534 | 588 | 636 | 672 | 708 | 749 | 791 | 831 | 0.0896 | 673 | 1.056 | 79.26 | 20.40 | 1 | 0.1128 | 187 | 0.0037 | 8.63 | 5.897 | 0.3770 | 453371.0 | 321000000 | 233000000000 | 172000000000000 | 0.3992 | 0.2328 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0029 | 0.0000 | 0.0098 | 0.0018 | 0.0479 | 0.0231 | 0.0685 | 0.0358 | 0.0607 | 0.0219 | 0.0881 | 0.0328 | 0.7202 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0018 | 0.0283 | 0.0231 | 0.0358 | 0.0358 | 0.0253 | 0.0219 | 0.0365 | 0.0328 | 0.8718 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0000 | 0.0344 | 0.0000 | 0.0531 | 0.0000 | 0.0531 | 0.0000 | 0.0688 | 0.0000 | 0.1000 | 0.0000 | 0.6781 | 0.0000 | 0.0011 | 0.0011 | 0.0034 | 0.0135 | 0.0270 | 0.0529 | 0.0450 | 0.0541 | 0.8018 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 12 | 17 | 0.1063 | 2.38 | 1.499 | 0.4250 | 5680.0 | 3330000 | 2380000000 | 1890000000000 | 0.4909 | 0.1207 | 0.0780 | 0.0610 | 0.2110 | 0.0749 | 0.2844 | 0.0999 | 0.2661 | 0.1207 | 0.0826 | 0.1914 | 0.0505 | 0.1692 | 0.0092 | 0.0874 | 0.0138 | 0.0707 | 0.0046 | 0.1248 | 0.0181 | 0.0352 | 0.0233 | 0.0424 | 0.0194 | 0.0488 | 0.0440 | 0.0456 | 0.0660 | 0.0697 | 0.0699 | 0.0689 | 0.0621 | 0.0817 | 0.0776 | 0.0961 | 0.6197 | 0.5116 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0054 | 0.0000 | 0.0090 | 0.0189 | 0.0667 | 0.0682 | 0.1189 | 0.0928 | 0.0360 | 0.0625 | 0.0811 | 0.0795 | 0.6829 | 0.6761 | 0.0016 | 0.0064 | 0.0096 | 0.0305 | 0.0595 | 0.0691 | 0.0740 | 0.0804 | 0.6688 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 214 | 52 | | 4675 | 12509 | 132.0 | 40.47 | 117.04 | 94.59 | 92 | 100 | 107 | 113 | 121 | 132 | 145 | 161 | 189 | 0.0803 | 1005 | 0.655 | 96.30 | 21.02 | 2 | 0.0560 | 262 | 0.0021 | 28.90 | 6.597 | 0.2326 | 19052.3 | 3020000 | 527000000 | 100000000000 | 0.4138 | 0.2308 | 0.0008 | 0.0003 | 0.0068 | 0.0003 | 0.0194 | 0.0015 | 0.0520 | 0.0078 | 0.1348 | 0.0341 | 0.1753 | 0.0664 | 0.1715 | 0.0721 | 0.1800 | 0.1079 | 0.2594 | 0.7097 | 0.0006 | 0.0000 | 0.0027 | 0.0000 | 0.0104 | 0.0007 | 0.0207 | 0.0027 | 0.0584 | 0.0188 | 0.0768 | 0.0358 | 0.0788 | 0.0298 | 0.1108 | 0.0522 | 0.6408 | 0.8601 | 0.0020 | 0.0038 | 0.0070 | 0.0150 | 0.0209 | 0.0282 | 0.0407 | 0.0846 | 0.1132 | 0.1372 | 0.1420 | 0.1541 | 0.1231 | 0.1316 | 0.1480 | 0.1447 | 0.4032 | 0.3008 | 0.0021 | 0.0043 | 0.0134 | 0.0417 | 0.0759 | 0.1027 | 0.0861 | 0.1294 | 0.5444 | 26 | 40 | 56 | 73 | 92 | 113 | 140 | 176 | 239 | 0.0031 | 25.48 | 6.462 | 0.3039 | 22644.4 | 6150000 | 2080000000 | 812000000000 | 0.4477 | 0.1962 | 0.0142 | 0.0021 | 0.0519 | 0.0093 | 0.1197 | 0.0219 | 0.1744 | 0.0608 | 0.1903 | 0.1276 | 0.1761 | 0.1685 | 0.1335 | 0.1621 | 0.0917 | 0.1797 | 0.0483 | 0.2680 | 0.0015 | 0.0008 | 0.0032 | 0.0034 | 0.0108 | 0.0069 | 0.0246 | 0.0184 | 0.0594 | 0.0480 | 0.0968 | 0.0772 | 0.0801 | 0.0743 | 0.1071 | 0.1012 | 0.6165 | 0.6698 | 0.0048 | 0.0042 | 0.0083 | 0.0087 | 0.0124 | 0.0192 | 0.0423 | 0.0439 | 0.0721 | 0.0829 | 0.1074 | 0.1257 | 0.0921 | 0.1041 | 0.1327 | 0.1351 | 0.5279 | 0.4761 | 0.0027 | 0.0064 | 0.0140 | 0.0311 | 0.0705 | 0.1082 | 0.0827 | 0.1082 | 0.5761 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 849 | 648 | | 5112 | 6565 | 125.8 | 31.35 | 178.35 | 174.51 | 89 | 99 | 108 | 116 | 122 | 129 | 138 | 149 | 167 | 0.1097 | 720 | 1.162 | 109.62 | 38.12 | 1 | 0.0534 | 273 | 0.0023 | 21.62 | 6.373 | 0.2588 | 16819.2 | 2390000 | 363000000 | 58800000000 | 0.4232 | 0.2346 | 0.0006 | 0.0000 | 0.0042 | 0.0000 | 0.0130 | 0.0002 | 0.0250 | 0.0036 | 0.0815 | 0.0212 | 0.1644 | 0.0559 | 0.1624 | 0.0520 | 0.1722 | 0.0780 | 0.3765 | 0.7890 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0012 | 0.0000 | 0.0055 | 0.0006 | 0.0352 | 0.0126 | 0.0852 | 0.0358 | 0.0745 | 0.0194 | 0.0985 | 0.0372 | 0.6986 | 0.8945 | 0.0022 | 0.0030 | 0.0087 | 0.0208 | 0.0282 | 0.0653 | 0.1062 | 0.1187 | 0.1593 | 0.1988 | 0.1907 | 0.1691 | 0.1192 | 0.1128 | 0.1148 | 0.0950 | 0.2709 | 0.2166 | 0.0022 | 0.0052 | 0.0108 | 0.0388 | 0.1086 | 0.1483 | 0.1198 | 0.1362 | 0.4302 | 16 | 28 | 49 | 82 | 120 | 170 | 233 | 311 | 426 | 0.0054 | 96.61 | 6.816 | 0.3013 | 62256.2 | 29200000 | 16400000000 | 10300000000000 | 0.4788 | 0.1616 | 0.0394 | 0.0012 | 0.1386 | 0.0088 | 0.2664 | 0.0649 | 0.1673 | 0.1257 | 0.1589 | 0.1784 | 0.1147 | 0.2041 | 0.0514 | 0.1509 | 0.0346 | 0.1222 | 0.0287 | 0.1439 | 0.0000 | 0.0003 | 0.0007 | 0.0000 | 0.0023 | 0.0011 | 0.0171 | 0.0077 | 0.0635 | 0.0541 | 0.1070 | 0.0913 | 0.0846 | 0.0677 | 0.1084 | 0.1006 | 0.6164 | 0.6772 | 0.0009 | 0.0000 | 0.0023 | 0.0028 | 0.0070 | 0.0083 | 0.0232 | 0.0319 | 0.0859 | 0.0979 | 0.1226 | 0.1364 | 0.0878 | 0.0974 | 0.1333 | 0.1320 | 0.5369 | 0.4934 | 0.0008 | 0.0008 | 0.0055 | 0.0169 | 0.0777 | 0.1131 | 0.0868 | 0.1190 | 0.5795 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 173 | 580 | | 3314 | 11955 | 517.2 | 91.88 | 119.57 | 243.85 | 373 | 433 | 487 | 512 | 531 | 550 | 573 | 598 | 624 | 0.0613 | 733 | 0.446 | 104.39 | 23.32 | 3 | 0.0993 | 329 | 0.0010 | 41.90 | 7.124 | 0.2030 | 275939.0 | 151000000 | 84400000000 | 48000000000000 | 0.4375 | 0.1965 | 0.0000 | 0.0000 | 0.0029 | 0.0003 | 0.0017 | 0.0003 | 0.0071 | 0.0009 | 0.0384 | 0.0163 | 0.0744 | 0.0359 | 0.0660 | 0.0157 | 0.0994 | 0.0273 | 0.7101 | 0.9033 | 0.0000 | 0.0000 | 0.0011 | 0.0003 | 0.0000 | 0.0003 | 0.0014 | 0.0009 | 0.0206 | 0.0163 | 0.0343 | 0.0359 | 0.0220 | 0.0157 | 0.0354 | 0.0273 | 0.8851 | 0.9033 | 0.0134 | 0.0000 | 0.0160 | 0.0000 | 0.0428 | 0.0000 | 0.0856 | 0.0000 | 0.1096 | 0.0000 | 0.1791 | 0.0000 | 0.1123 | 0.0000 | 0.1417 | 0.0000 | 0.2995 | 0.0000 | 0.0005 | 0.0042 | 0.0094 | 0.0141 | 0.0381 | 0.0522 | 0.0637 | 0.0914 | 0.7262 | 9 | 12 | 14 | 16 | 21 | 31 | 57 | 130 | 371 | 0.1465 | 4.98 | 3.299 | 0.6421 | 73753.8 | 72700000 | 87000000000 | 116000000000000 | 0.4905 | 0.1557 | 0.0398 | 0.0000 | 0.1155 | 0.0121 | 0.1474 | 0.0864 | 0.1932 | 0.1021 | 0.1972 | 0.1690 | 0.1554 | 0.1820 | 0.0777 | 0.1328 | 0.0498 | 0.1235 | 0.0239 | 0.1922 | 0.0000 | 0.0000 | 0.0025 | 0.0012 | 0.0051 | 0.0044 | 0.0108 | 0.0097 | 0.0375 | 0.0400 | 0.0563 | 0.0512 | 0.0512 | 0.0465 | 0.0776 | 0.0787 | 0.7589 | 0.7684 | 0.0000 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0028 | 0.0119 | 0.0127 | 0.0419 | 0.0409 | 0.0608 | 0.0682 | 0.0591 | 0.0564 | 0.0784 | 0.0804 | 0.7466 | 0.7377 | 0.0008 | 0.0008 | 0.0028 | 0.0097 | 0.0399 | 0.0565 | 0.0480 | 0.0871 | 0.7543 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 472 | 429 | | 2702 | 12483 | 298.7 | 39.90 | 33.75 | 65.19 | 243 | 264 | 280 | 292 | 303 | 312 | 321 | 330 | 347 | 0.0569 | 710 | 0.587 | 156.06 | 44.65 | 2 | 0.1991 | 538 | 0.0038 | 12.01 | 5.909 | 0.3178 | 90794.9 | 28100000 | 8800000000 | 2800000000000 | 0.4181 | 0.2189 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0082 | 0.0004 | 0.0381 | 0.0222 | 0.0559 | 0.0359 | 0.0563 | 0.0200 | 0.0858 | 0.0333 | 0.7552 | 0.8882 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0045 | 0.0004 | 0.0288 | 0.0222 | 0.0365 | 0.0359 | 0.0337 | 0.0200 | 0.0483 | 0.0333 | 0.8479 | 0.8882 | 0.0064 | 0.0000 | 0.0446 | 0.0000 | 0.0318 | 0.0000 | 0.1019 | 0.0000 | 0.1338 | 0.0000 | 0.1656 | 0.0000 | 0.1529 | 0.0000 | 0.1338 | 0.0000 | 0.2293 | 0.0000 | 0.0000 | 0.0014 | 0.0095 | 0.0210 | 0.0535 | 0.0947 | 0.0947 | 0.1238 | 0.6015 | 7 | 9 | 10 | 11 | 13 | 16 | 21 | 29 | 72 | 0.2585 | 2.84 | 2.563 | 0.8124 | 5388.1 | 1890000 | 937000000 | 558000000000 | 0.6147 | 0.0974 | 0.0312 | 0.0161 | 0.0775 | 0.0194 | 0.0763 | 0.0317 | 0.1329 | 0.0506 | 0.1699 | 0.1013 | 0.1642 | 0.1079 | 0.1780 | 0.1240 | 0.1202 | 0.1614 | 0.0497 | 0.3876 | 0.0063 | 0.0091 | 0.0118 | 0.0101 | 0.0074 | 0.0133 | 0.0221 | 0.0195 | 0.0505 | 0.0405 | 0.0660 | 0.0549 | 0.0705 | 0.0613 | 0.0989 | 0.0965 | 0.6665 | 0.6947 | 0.0038 | 0.0000 | 0.0065 | 0.0043 | 0.0076 | 0.0049 | 0.0244 | 0.0232 | 0.0455 | 0.0452 | 0.0764 | 0.0757 | 0.0585 | 0.0550 | 0.0748 | 0.0794 | 0.7026 | 0.7123 | 0.0014 | 0.0082 | 0.0096 | 0.0227 | 0.0537 | 0.0719 | 0.0637 | 0.0928 | 0.6761 |