High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
BT-20 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 958 125 image if available 2932 10604 196.6 65.96 9.01 4.41 127 138 150 164 179 198 223 249 301 0.0658 698 0.614 76.01 21.95 1 0.0836 245 0.0079 2.74 5.180 0.5006 42980.6
10400000
2760000000
788000000000
0.4076 0.2304 0.0043 0.0013 0.0035 0.0013 0.0112 0.0042 0.0371 0.0097 0.0569 0.0295 0.1320 0.0687 0.1217 0.0442 0.1639 0.0720 0.4694 0.7692 0.0021 0.0011 0.0021 0.0007 0.0053 0.0032 0.0137 0.0064 0.0217 0.0207 0.0455 0.0454 0.0418 0.0264 0.0561 0.0482 0.8117 0.8477 0.0014 0.0000 0.0014 0.0000 0.0109 0.0047 0.0301 0.0165 0.0342 0.0425 0.0861 0.0778 0.0697 0.0472 0.0765 0.0802 0.6899 0.7311 0.0017 0.0025 0.0042 0.0151 0.0260 0.0519 0.0511 0.0611 0.7864 5 6 7 7 8 9 10 11 14 0.0111 13.72 5.076 0.3038 100.7
1416.1
25055.2
539238
0.4587 0.1802 0.0400 0.0040 0.1247 0.0070 0.2092 0.0206 0.2582 0.0465 0.1991 0.1010 0.1141 0.1792 0.0447 0.2550 0.0098 0.2595 0.0003 0.1273 0.0087 0.0002 0.0392 0.0012 0.0841 0.0078 0.1282 0.0233 0.1444 0.0654 0.1470 0.1201 0.1169 0.1781 0.1209 0.2377 0.2107 0.3662 0.1147 0.1071 0.0900 0.0750 0.0862 0.0679 0.0718 0.0968 0.0938 0.0859 0.1045 0.1000 0.0836 0.1019 0.0957 0.1167 0.2595 0.2487 0.0483 0.0956 0.1102 0.1089 0.1085 0.0986 0.0902 0.1128 0.2269
SK-BR-3 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 1017 174 image if available 1248 1851 214.5 155.04 45.32 44.12 105 122 135 145 159 175 196 246 453 0.2150 398 0.886 138.05 45.25 2 0.3045 380 0.0030 54.71 6.166 0.2695 70037.8
33300000
19600000000
12700000000000
0.3408 0.2642 0.0000 0.0014 0.0105 0.0000 0.0592 0.0027 0.0941 0.0095 0.2056 0.0846 0.1638 0.1419 0.0906 0.1132 0.1289 0.1050 0.2474 0.5416 0.0000 0.0011 0.0000 0.0000 0.0076 0.0011 0.0191 0.0085 0.0841 0.0512 0.1071 0.0800 0.0650 0.0597 0.1071 0.0778 0.6099 0.7207 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0169 0.0098 0.0805 0.1073 0.1059 0.1024 0.0551 0.0488 0.0975 0.1024 0.6441 0.6293 0.0032 0.0097 0.0097 0.0130 0.0909 0.0942 0.0390 0.1039 0.6364 20 22 25 27 30 34 39 51 87 0.1634 0.96 2.528 0.7872 4000.0
623754
127000000
29000000000
0.5672 0.0956 0.0344 0.0145 0.0875 0.0190 0.1375 0.0335 0.1313 0.0760 0.1906 0.1229 0.2000 0.1508 0.1156 0.1620 0.0688 0.1721 0.0344 0.2492 0.0106 0.0111 0.0257 0.0146 0.0287 0.0231 0.0332 0.0446 0.0861 0.0788 0.1344 0.0925 0.1239 0.1071 0.1360 0.1500 0.4215 0.4781 0.0029 0.0037 0.0088 0.0368 0.0205 0.0404 0.0526 0.0772 0.1404 0.0919 0.1725 0.1287 0.1023 0.1213 0.1287 0.1103 0.3713 0.3897 0.0022 0.0155 0.0310 0.0376 0.1062 0.1372 0.1261 0.1482 0.3960
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 481 100 image if available 7950 9207 278.6 129.42 10.26 12.06 144 163 187 215 241 273 314 413 495 0.0924 851 0.695 94.53 15.03 6 0.0267 212 0.0018 9.35 6.724 0.3596 94338.5
37400000
16500000000
7810000000000
0.4212 0.2162 0.0009 0.0016 0.0013 0.0016 0.0068 0.0043 0.0175 0.0086 0.0554 0.0374 0.0967 0.0491 0.0797 0.0423 0.1121 0.0623 0.6297 0.7930 0.0004 0.0011 0.0007 0.0010 0.0027 0.0027 0.0064 0.0047 0.0202 0.0199 0.0282 0.0236 0.0285 0.0216 0.0407 0.0308 0.8721 0.8946 0.0009 0.0000 0.0009 0.0000 0.0028 0.0017 0.0070 0.0091 0.0167 0.0205 0.0423 0.0400 0.0265 0.0377 0.0307 0.0354 0.8721 0.8556 0.0010 0.0016 0.0049 0.0092 0.0191 0.0384 0.0309 0.0427 0.8521 3 5 5 6 7 8 9 11 19 0.1322 0.45 1.509 0.5124 250.6
12213
813301
62700000
0.5153 0.1526 0.0886 0.0079 0.2162 0.0407 0.2503 0.0797 0.2088 0.1421 0.1362 0.1824 0.0696 0.1959 0.0225 0.1743 0.0078 0.1275 0.0000 0.0493 0.0425 0.0045 0.1012 0.0274 0.1320 0.0540 0.1129 0.0995 0.0975 0.1431 0.0935 0.1554 0.0649 0.1304 0.0728 0.1196 0.2827 0.2662 0.0790 0.0376 0.0515 0.0295 0.0334 0.0302 0.0322 0.0376 0.0632 0.0604 0.0971 0.1150 0.0872 0.0825 0.0989 0.1098 0.4576 0.4974 0.1005 0.0895 0.0781 0.0561 0.0570 0.0875 0.0557 0.0858 0.3897
MCF7 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 162 234 image if available 7241 33553 311.8 96.47 118.63 162.69 187 201 237 287 318 345 372 400 436 0.0350 1175 0.651 97.19 15.30 2 0.0305 221 0.0011 37.81 7.274 0.2128 106500.0
39100000
15200000000
6200000000000
0.4774 0.1776 0.0004 0.0012 0.0025 0.0024 0.0078 0.0057 0.0252 0.0134 0.0900 0.0431 0.1460 0.0745 0.1488 0.0709 0.1729 0.1150 0.4064 0.6737 0.0000 0.0011 0.0000 0.0020 0.0012 0.0045 0.0020 0.0085 0.0163 0.0263 0.0285 0.0387 0.0281 0.0343 0.0386 0.0461 0.8853 0.8385 0.0024 0.0155 0.0043 0.0127 0.0119 0.0325 0.0396 0.0876 0.0835 0.1441 0.1098 0.1935 0.1150 0.1483 0.1394 0.1384 0.4940 0.2274 0.0000 0.0011 0.0029 0.0135 0.0296 0.0630 0.0643 0.0849 0.7407 9 11 14 19 34 73 138 222 342 0.1019 11.63 4.467 0.5909 40541.7
20200000
12600000000
9300000000000
0.3536 0.3217 0.0195 0.0035 0.1006 0.0081 0.1840 0.0477 0.1733 0.1043 0.1800 0.1722 0.1418 0.1779 0.1082 0.1344 0.0594 0.1368 0.0332 0.2151 0.0001 0.0006 0.0006 0.0005 0.0020 0.0011 0.0085 0.0076 0.0341 0.0295 0.0563 0.0485 0.0428 0.0362 0.0619 0.0541 0.7937 0.8219 0.0001 0.0002 0.0013 0.0015 0.0028 0.0035 0.0110 0.0135 0.0448 0.0478 0.0745 0.0869 0.0567 0.0645 0.0842 0.0980 0.7246 0.6843 0.0002 0.0009 0.0028 0.0099 0.0385 0.0629 0.0519 0.0705 0.7623
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 785 881 image if available 3192 11680 293.5 228.83 175.43 253.66 121 132 141 152 168 234 343 454 665 0.0779 910 0.548 96.01 23.41 1 0.0883 282 0.0123 12.19 5.534 0.4708 138508.0
89800000
68800000000
57800000000000
0.3485 0.2740 0.0000 0.0026 0.0088 0.0040 0.0234 0.0026 0.0848 0.0145 0.2193 0.0818 0.2339 0.1385 0.0994 0.0989 0.1053 0.1280 0.2251 0.5290 0.0000 0.0013 0.0000 0.0020 0.0000 0.0013 0.0039 0.0040 0.0308 0.0246 0.0394 0.0378 0.0308 0.0252 0.0450 0.0358 0.8502 0.8680 0.0011 0.0000 0.0000 0.0000 0.0022 0.0013 0.0043 0.0053 0.0335 0.0427 0.0475 0.0521 0.0367 0.0427 0.0583 0.0681 0.8164 0.7877 0.0000 0.0000 0.0000 0.0046 0.0316 0.0418 0.0316 0.0501 0.8403 8 11 13 16 30 86 182 350 586 0.1317 8.32 4.290 0.5950 95114.7
66900000
53100000000
45800000000000
0.4601 0.1966 0.0174 0.0027 0.1172 0.0096 0.2084 0.0541 0.1852 0.1021 0.1881 0.1568 0.1389 0.1637 0.0767 0.1301 0.0449 0.1548 0.0232 0.2260 0.0003 0.0000 0.0003 0.0005 0.0025 0.0018 0.0104 0.0100 0.0440 0.0382 0.0552 0.0567 0.0575 0.0473 0.0699 0.0678 0.7600 0.7777 0.0000 0.0007 0.0022 0.0027 0.0040 0.0065 0.0160 0.0143 0.0413 0.0419 0.0703 0.0671 0.0518 0.0504 0.0679 0.0740 0.7465 0.7423 0.0000 0.0020 0.0031 0.0134 0.0431 0.0641 0.0532 0.0661 0.7549
MCF7 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 927 887 image if available 3637 16754 208.9 92.53 65.01 116.76 121 135 144 158 179 205 235 270 358 0.0556 932 0.834 150.33 54.74 2 0.1270 462 0.0037 12.92 6.141 0.3836 52205.7
15500000
5250000000
1970000000000
0.4763 0.1819 0.0019 0.0015 0.0029 0.0023 0.0229 0.0034 0.0381 0.0138 0.0705 0.0356 0.0896 0.0521 0.0925 0.0502 0.1211 0.0705 0.5605 0.7705 0.0010 0.0013 0.0010 0.0016 0.0050 0.0022 0.0076 0.0094 0.0222 0.0216 0.0443 0.0388 0.0267 0.0297 0.0489 0.0503 0.8433 0.8452 0.0021 0.0000 0.0011 0.0068 0.0064 0.0034 0.0139 0.0051 0.0502 0.0425 0.0694 0.0969 0.0491 0.0459 0.0780 0.0986 0.7297 0.7007 0.0014 0.0021 0.0014 0.0057 0.0291 0.0704 0.0455 0.0824 0.7619 5 7 8 10 13 21 44 90 198 0.1255 5.70 3.389 0.6022 17857.4
7770000
4140000000
2500000000000
0.4976 0.1519 0.0344 0.0046 0.1527 0.0207 0.2796 0.0718 0.1989 0.1314 0.1452 0.1840 0.0882 0.2058 0.0527 0.1436 0.0312 0.1193 0.0172 0.1188 0.0002 0.0009 0.0019 0.0019 0.0043 0.0024 0.0143 0.0145 0.0517 0.0443 0.0853 0.0765 0.0530 0.0575 0.0866 0.0815 0.7027 0.7204 0.0003 0.0012 0.0024 0.0039 0.0053 0.0051 0.0173 0.0170 0.0587 0.0670 0.1025 0.1053 0.0672 0.0804 0.1014 0.1071 0.6449 0.6130 0.0012 0.0022 0.0050 0.0146 0.0566 0.0853 0.0609 0.1035 0.6707
MDA-MB-231 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 632 365 image if available 4889 13256 383.0 256.14 34.30 57.66 183 197 211 228 257 316 420 590 842 0.0671 890 0.504 95.59 26.87 10 0.0714 349 0.0027 26.56 6.768 0.3301 212277.0
153000000
126000000000
111000000000000
0.4295 0.1988 0.0014 0.0022 0.0000 0.0011 0.0177 0.0092 0.0477 0.0152 0.1376 0.0656 0.2030 0.1062 0.1444 0.0846 0.1253 0.1084 0.3229 0.6076 0.0000 0.0014 0.0000 0.0007 0.0010 0.0058 0.0030 0.0093 0.0272 0.0319 0.0495 0.0436 0.0302 0.0367 0.0475 0.0480 0.8417 0.8226 0.0000 0.0019 0.0000 0.0000 0.0039 0.0000 0.0070 0.0056 0.0396 0.0318 0.0591 0.0589 0.0311 0.0308 0.0521 0.0421 0.8073 0.8290 0.0000 0.0000 0.0000 0.0055 0.0325 0.0644 0.0319 0.0576 0.8081 6 7 9 11 13 17 25 40 85 0.1143 7.18 3.518 0.6992 4501.5
1130000
367000000
138000000000
0.5010 0.1794 0.0284 0.0102 0.0869 0.0191 0.1446 0.0339 0.1683 0.0750 0.1629 0.1280 0.1299 0.1522 0.1034 0.1314 0.1052 0.1526 0.0704 0.2976 0.0040 0.0039 0.0059 0.0071 0.0075 0.0092 0.0215 0.0184 0.0557 0.0417 0.0796 0.0708 0.0632 0.0565 0.0866 0.0877 0.6759 0.7047 0.0019 0.0022 0.0019 0.0013 0.0095 0.0056 0.0175 0.0233 0.0712 0.0739 0.1086 0.1188 0.0712 0.0774 0.1036 0.1059 0.6145 0.5916 0.0032 0.0064 0.0051 0.0185 0.0543 0.1006 0.0716 0.1016 0.6387
Hs 578T A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 653 516 image if available 909 892 22.8 11.51 5.20 1.87 10 12 15 18 21 23 27 31 38 0.3509 313 1.192 32.02 13.34 0 0.0957 87 0.0035 17.77 5.844 0.2797 651.5
22448.7
894003
39700000
0.3319 0.2816 0.0000 0.0019 0.0202 0.0000 0.0847 0.0133 0.0605 0.0475 0.1613 0.0665 0.2016 0.1141 0.1855 0.1255 0.1935 0.1464 0.0927 0.4848 0.0000 0.0015 0.0019 0.0000 0.0135 0.0073 0.0250 0.0219 0.0442 0.0335 0.0673 0.0510 0.0635 0.0496 0.0865 0.0700 0.6981 0.7653 0.0000 0.0063 0.0000 0.0063 0.0000 0.0313 0.0478 0.0750 0.0772 0.0938 0.1103 0.1313 0.0809 0.1125 0.0846 0.0875 0.5993 0.4563 0.0051 0.0077 0.0077 0.0281 0.0537 0.0793 0.0793 0.0997 0.6394 3 4 4 5 5 6 6 7 8 0.0223 7.70 4.011 0.3535 30.5
195.177
1334.83
9619.86
0.5452 0.1074 0.0732 0.0034 0.1616 0.0358 0.2500 0.0903 0.2348 0.1652 0.1372 0.2129 0.1067 0.2215 0.0244 0.1567 0.0091 0.0716 0.0030 0.0426 0.0000 0.0000 0.0070 0.0000 0.0377 0.0061 0.0934 0.0547 0.1506 0.1106 0.2218 0.1385 0.1869 0.1823 0.2050 0.2272 0.0976 0.2807 0.0334 0.1483 0.1517 0.3347 0.2699 0.3051 0.2416 0.1525 0.1645 0.0551 0.0848 0.0042 0.0437 0.0000 0.0103 0.0000 0.0000 0.0000 0.0071 0.0321 0.1214 0.1821 0.2304 0.2054 0.1232 0.0804 0.0179
Hs 578T A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 372 139 image if available 4417 11190 35.9 14.42 6.81 2.68 18 23 27 31 35 38 42 47 55 0.1108 1240 0.972 96.52 27.73 0 0.0541 239 0.0016 19.80 6.657 0.2399 1496.0
70708.7
3720000
215000000
0.3566 0.2612 0.0074 0.0033 0.0138 0.0046 0.0275 0.0100 0.0401 0.0219 0.0682 0.0306 0.1181 0.0604 0.1456 0.0764 0.2189 0.1249 0.3605 0.6679 0.0027 0.0016 0.0044 0.0025 0.0061 0.0041 0.0123 0.0106 0.0194 0.0144 0.0310 0.0289 0.0358 0.0324 0.0607 0.0501 0.8275 0.8554 0.0135 0.0136 0.0143 0.0303 0.0236 0.0394 0.0412 0.0455 0.0648 0.0636 0.0732 0.0924 0.0875 0.1030 0.1052 0.1288 0.5766 0.4833 0.0024 0.0118 0.0142 0.0217 0.0307 0.0558 0.0728 0.1281 0.6626 3 4 5 6 7 7 8 9 10 0.0130 14.88 4.690 0.2835 53.5
466.389
4418.91
44994.1
0.5386 0.1220 0.0193 0.0018 0.0771 0.0147 0.1782 0.0531 0.2352 0.1151 0.2415 0.1932 0.1553 0.2539 0.0676 0.2164 0.0219 0.1202 0.0039 0.0316 0.0009 0.0001 0.0099 0.0021 0.0376 0.0123 0.0944 0.0380 0.1707 0.0873 0.2304 0.1689 0.2167 0.2533 0.1681 0.2793 0.0711 0.1586 0.1499 0.2801 0.2687 0.3198 0.2320 0.2121 0.1617 0.1088 0.0909 0.0480 0.0568 0.0201 0.0279 0.0084 0.0099 0.0022 0.0022 0.0006 0.0072 0.0437 0.1150 0.1799 0.2208 0.1990 0.1331 0.0731 0.0283
MCF7 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1201 147 image if available 25401 21792 80.3 36.47 7.79 3.16 47 51 55 60 67 79 95 111 130 0.0646 1407 0.643 109.48 22.02 3 0.0122 311 0.0238 1.54 4.339 0.6433 7784.7
930349
141000000
27400000000
0.3746 0.2574 0.0183 0.0041 0.0285 0.0101 0.0332 0.0165 0.0445 0.0216 0.0579 0.0307 0.0760 0.0454 0.0991 0.0645 0.1547 0.1011 0.4878 0.7059 0.0063 0.0025 0.0088 0.0051 0.0101 0.0093 0.0128 0.0127 0.0158 0.0171 0.0202 0.0254 0.0263 0.0353 0.0450 0.0545 0.8547 0.8381 0.0029 0.0096 0.0051 0.0076 0.0087 0.0135 0.0154 0.0237 0.0181 0.0317 0.0252 0.0416 0.0356 0.0590 0.0614 0.0833 0.8277 0.7300 0.0039 0.0045 0.0066 0.0106 0.0121 0.0194 0.0250 0.0402 0.8777 4 5 6 7 8 9 9 10 12 0.3288 0.54 1.489 0.7679 70.7
710.738
7758.34
90867.1
0.5651 0.1468 0.0276 0.0002 0.1012 0.0027 0.1830 0.0162 0.2395 0.0448 0.2232 0.1065 0.1440 0.1983 0.0622 0.2724 0.0175 0.2494 0.0018 0.1095 0.0011 0.0001 0.0095 0.0007 0.0313 0.0047 0.0743 0.0148 0.1392 0.0405 0.2209 0.1002 0.2544 0.1989 0.1985 0.3291 0.0707 0.3109 0.0837 0.3817 0.2220 0.3524 0.2715 0.1695 0.2102 0.0699 0.1317 0.0232 0.0547 0.0028 0.0218 0.0004 0.0035 0.0000 0.0010 0.0000 0.0061 0.0422 0.1149 0.1974 0.2403 0.2128 0.1308 0.0484 0.0072
SK-BR-3 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 524 311 image if available 7833 16316 159.4 129.05 84.65 174.06 65 76 86 97 114 131 150 185 382 0.0834 1360 1.188 60.96 23.71 5 0.0200 157 0.0057 7.18 5.903 0.4831 42052.4
16100000
7440000000
3750000000000
0.4134 0.2024 0.0022 0.0044 0.0039 0.0032 0.0061 0.0041 0.0335 0.0116 0.0754 0.0367 0.0972 0.0576 0.0972 0.0547 0.1056 0.0789 0.5788 0.7488 0.0012 0.0031 0.0021 0.0023 0.0027 0.0029 0.0140 0.0079 0.0273 0.0211 0.0334 0.0280 0.0404 0.0320 0.0507 0.0445 0.8282 0.8580 0.0007 0.0000 0.0007 0.0000 0.0033 0.0000 0.0086 0.0022 0.0213 0.0230 0.0452 0.0445 0.0219 0.0208 0.0359 0.0408 0.8625 0.8687 0.0005 0.0039 0.0043 0.0096 0.0294 0.0487 0.0352 0.0545 0.8140 8 10 12 15 18 24 39 87 242 0.1992 8.64 2.988 0.7068 37461.6
26400000
22100000000
20600000000000
0.5330 0.1352 0.0090 0.0029 0.0336 0.0070 0.0493 0.0187 0.1087 0.0531 0.1659 0.0904 0.1839 0.1376 0.1390 0.1405 0.1312 0.1359 0.1794 0.4140 0.0005 0.0009 0.0029 0.0023 0.0029 0.0042 0.0098 0.0168 0.0383 0.0349 0.0554 0.0519 0.0449 0.0496 0.0660 0.0575 0.7794 0.7817 0.0021 0.0004 0.0017 0.0035 0.0045 0.0047 0.0141 0.0116 0.0497 0.0520 0.0783 0.0849 0.0583 0.0621 0.0852 0.0791 0.7060 0.7017 0.0009 0.0033 0.0045 0.0117 0.0415 0.0667 0.0505 0.0739 0.7471
MCF7 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1103 521 image if available 38572 41531 83.7 70.09 7.10 2.74 45 48 50 53 56 62 73 98 152 0.0457 1898 0.782 128.16 45.34 3 0.0101 390 0.0492 1.50 4.084 0.6882 11919.8
2870000
920000000
334000000000
0.4510 0.1895 0.0109 0.0089 0.0164 0.0172 0.0246 0.0246 0.0351 0.0389 0.0605 0.0504 0.0801 0.0590 0.0958 0.0673 0.1409 0.0885 0.5357 0.6452 0.0040 0.0067 0.0055 0.0130 0.0089 0.0188 0.0105 0.0286 0.0183 0.0354 0.0237 0.0412 0.0271 0.0468 0.0418 0.0594 0.8604 0.7500 0.0015 0.0009 0.0027 0.0019 0.0047 0.0041 0.0104 0.0090 0.0173 0.0159 0.0259 0.0282 0.0314 0.0309 0.0401 0.0398 0.8660 0.8695 0.0020 0.0024 0.0056 0.0088 0.0174 0.0214 0.0294 0.0366 0.8764 4 5 6 6 7 8 8 9 11 0.4747 0.33 1.180 0.8414 57.9
527.37
5295.83
58155.7
0.4995 0.1829 0.0184 0.0024 0.0723 0.0096 0.1551 0.0301 0.2242 0.0749 0.2394 0.1555 0.1742 0.2423 0.0889 0.2556 0.0251 0.1713 0.0024 0.0583 0.0022 0.0001 0.0106 0.0010 0.0291 0.0053 0.0623 0.0178 0.1060 0.0556 0.1606 0.1162 0.2066 0.1940 0.2316 0.2914 0.1910 0.3187 0.0905 0.1632 0.1612 0.2060 0.1796 0.1882 0.1754 0.1469 0.1412 0.1102 0.1007 0.0685 0.0624 0.0461 0.0489 0.0412 0.0401 0.0296 0.0110 0.0392 0.0830 0.1233 0.1517 0.1724 0.1677 0.1502 0.1015
Hs 578T Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 125 887 image if available 914 10249 57.4 40.69 232.85 304.99 28 31 33 35 38 42 56 82 127 0.0631 647 1.229 27.66 9.43 1 0.0722 66 0.0076 22.99 5.445 0.3165 4951.9
588247
83100000
12800000000
0.3258 0.3035 0.0088 0.0152 0.0000 0.0127 0.0531 0.0482 0.1239 0.0736 0.3451 0.1624 0.2832 0.1574 0.1416 0.1650 0.0354 0.1421 0.0088 0.2234 0.0000 0.0103 0.0000 0.0086 0.0091 0.0325 0.0151 0.0462 0.0393 0.0856 0.0665 0.0805 0.0665 0.0702 0.0634 0.0771 0.7402 0.5890 0.0000 0.0053 0.0000 0.0000 0.0000 0.0000 0.0046 0.0211 0.0826 0.0842 0.0872 0.0579 0.0459 0.0737 0.1101 0.0895 0.6697 0.6684 0.0000 0.0000 0.0037 0.0297 0.0409 0.0632 0.0743 0.0706 0.7175 22 26 32 50 83 141 256 424 686 0.0356 29.95 5.321 0.4926 147227.0
131000000
137000000000
161000000000000
0.6516 0.0660 0.0697 0.0026 0.1780 0.0222 0.2107 0.0941 0.1395 0.1359 0.1543 0.1737 0.1157 0.1966 0.0772 0.1261 0.0356 0.1261 0.0193 0.1228 0.0008 0.0002 0.0011 0.0012 0.0025 0.0051 0.0195 0.0177 0.0641 0.0572 0.0786 0.0824 0.0675 0.0545 0.0853 0.0863 0.6804 0.6953 0.0010 0.0015 0.0031 0.0035 0.0062 0.0073 0.0244 0.0289 0.0714 0.0763 0.0975 0.0960 0.0752 0.0867 0.0962 0.1044 0.6250 0.5954 0.0006 0.0012 0.0046 0.0178 0.0705 0.0911 0.0644 0.0929 0.6569
Hs 578T Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 603 882 image if available 1319 7737 66.4 71.59 51.64 108.03 33 34 36 37 38 40 42 54 179 0.0778 602 1.235 41.48 16.64 4 0.0819 108 0.0362 35.18 4.239 0.5039 9528.0
2260000
632000000
189000000000
0.3313 0.2814 0.0000 0.0369 0.0984 0.0938 0.3770 0.0966 0.2295 0.0966 0.2623 0.0909 0.0328 0.1790 0.0000 0.1932 0.0000 0.1364 0.0000 0.0767 0.0000 0.0236 0.0036 0.0599 0.0036 0.0617 0.0073 0.0617 0.0584 0.0399 0.0730 0.0690 0.0474 0.0853 0.0766 0.0853 0.7299 0.5136 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0094 0.0101 0.0657 0.0653 0.0892 0.1005 0.0469 0.0503 0.0892 0.0804 0.6995 0.6935 0.0000 0.0000 0.0000 0.0170 0.0468 0.0979 0.0511 0.0638 0.7234 9 10 11 12 13 15 17 26 172 0.2813 8.15 2.652 0.7496 14334.9
6050000
2920000000
1530000000000
0.6889 0.0590 0.0938 0.0063 0.2313 0.0472 0.2375 0.1824 0.1813 0.1981 0.1000 0.2390 0.0938 0.1447 0.0250 0.0755 0.0313 0.0503 0.0063 0.0566 0.0000 0.0014 0.0008 0.0007 0.0031 0.0021 0.0178 0.0192 0.0666 0.0655 0.0860 0.0734 0.0713 0.0734 0.0953 0.0962 0.6592 0.6681 0.0000 0.0000 0.0009 0.0018 0.0035 0.0018 0.0221 0.0230 0.0716 0.0718 0.0902 0.0948 0.0875 0.0902 0.1043 0.0976 0.6198 0.6188 0.0008 0.0000 0.0017 0.0215 0.0710 0.0834 0.0859 0.0983 0.6375