High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 831 | 627 | | 22430 | 35732 | 126.0 | 38.62 | 252.74 | 227.53 | 82 | 95 | 104 | 113 | 121 | 131 | 142 | 157 | 179 | 0.0532 | 1901 | 0.880 | 73.43 | 20.81 | 2 | 0.0089 | 200 | 0.0017 | 21.99 | 6.753 | 0.2609 | 17379.7 | 2600000 | 417000000 | 71800000000 | 0.4412 | 0.2102 | 0.0006 | 0.0001 | 0.0021 | 0.0002 | 0.0088 | 0.0011 | 0.0346 | 0.0052 | 0.1045 | 0.0291 | 0.1823 | 0.0693 | 0.1643 | 0.0693 | 0.1767 | 0.0997 | 0.3261 | 0.7259 | 0.0002 | 0.0001 | 0.0008 | 0.0001 | 0.0022 | 0.0002 | 0.0101 | 0.0018 | 0.0357 | 0.0141 | 0.0709 | 0.0319 | 0.0688 | 0.0258 | 0.0917 | 0.0432 | 0.7197 | 0.8826 | 0.0034 | 0.0054 | 0.0050 | 0.0100 | 0.0140 | 0.0284 | 0.0533 | 0.0888 | 0.0998 | 0.1568 | 0.1659 | 0.2106 | 0.1164 | 0.1172 | 0.1451 | 0.1426 | 0.3972 | 0.2402 | 0.0011 | 0.0034 | 0.0087 | 0.0271 | 0.0720 | 0.1160 | 0.1006 | 0.1196 | 0.5516 | 16 | 33 | 75 | 138 | 204 | 273 | 343 | 432 | 576 | 0.0082 | 55.93 | 6.842 | 0.3237 | 115644.0 | 68100000 | 47400000000 | 37300000000000 | 0.5184 | 0.1555 | 0.0294 | 0.0010 | 0.1132 | 0.0078 | 0.2146 | 0.0613 | 0.1758 | 0.0954 | 0.1640 | 0.1647 | 0.1397 | 0.1993 | 0.0852 | 0.1472 | 0.0476 | 0.1393 | 0.0304 | 0.1840 | 0.0000 | 0.0002 | 0.0006 | 0.0007 | 0.0018 | 0.0015 | 0.0125 | 0.0070 | 0.0472 | 0.0386 | 0.0990 | 0.0797 | 0.0795 | 0.0590 | 0.1063 | 0.0906 | 0.6532 | 0.7227 | 0.0006 | 0.0013 | 0.0027 | 0.0029 | 0.0077 | 0.0109 | 0.0241 | 0.0340 | 0.0806 | 0.1011 | 0.1356 | 0.1539 | 0.1094 | 0.1178 | 0.1359 | 0.1438 | 0.5033 | 0.4344 | 0.0003 | 0.0016 | 0.0049 | 0.0169 | 0.0624 | 0.1189 | 0.0930 | 0.1202 | 0.5819 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 844 | | 2908 | 15413 | 16.0 | 5.68 | 6.17 | 2.21 | 10 | 12 | 13 | 14 | 15 | 16 | 18 | 19 | 22 | 0.0804 | 1239 | 1.278 | 24.04 | 7.81 | 0 | 0.0193 | 56 | 0.0081 | 8.98 | 5.211 | 0.3653 | 289.8 | 6020.69 | 146883 | 4220000 | 0.4199 | 0.2102 | 0.0085 | 0.0004 | 0.0216 | 0.0036 | 0.0385 | 0.0085 | 0.0745 | 0.0222 | 0.1137 | 0.0287 | 0.1476 | 0.0534 | 0.2149 | 0.0825 | 0.2097 | 0.1756 | 0.1711 | 0.6250 | 0.0052 | 0.0000 | 0.0124 | 0.0018 | 0.0204 | 0.0040 | 0.0261 | 0.0141 | 0.0461 | 0.0196 | 0.0518 | 0.0236 | 0.0969 | 0.0460 | 0.1330 | 0.0873 | 0.6081 | 0.8036 | 0.0279 | 0.0590 | 0.0540 | 0.0729 | 0.0714 | 0.0521 | 0.0976 | 0.0486 | 0.1063 | 0.0972 | 0.0871 | 0.1632 | 0.1080 | 0.1042 | 0.1307 | 0.1250 | 0.3171 | 0.2778 | 0.0127 | 0.0202 | 0.0254 | 0.0419 | 0.0538 | 0.0695 | 0.1046 | 0.1674 | 0.5045 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0174 | 10.89 | 4.353 | 0.3184 | 42.9 | 326.59 | 2675.72 | 23343.4 | 0.5105 | 0.1490 | 0.0093 | 0.0007 | 0.0467 | 0.0029 | 0.1332 | 0.0168 | 0.2261 | 0.0557 | 0.2649 | 0.1187 | 0.2015 | 0.1957 | 0.0932 | 0.2556 | 0.0225 | 0.2405 | 0.0026 | 0.1134 | 0.0005 | 0.0000 | 0.0014 | 0.0005 | 0.0117 | 0.0029 | 0.0395 | 0.0124 | 0.0975 | 0.0337 | 0.1985 | 0.0723 | 0.2678 | 0.1849 | 0.2578 | 0.3562 | 0.1253 | 0.3371 | 0.1026 | 0.2983 | 0.2437 | 0.3365 | 0.2794 | 0.2278 | 0.2269 | 0.0988 | 0.1028 | 0.0292 | 0.0369 | 0.0090 | 0.0071 | 0.0004 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0196 | 0.0575 | 0.1217 | 0.1919 | 0.2514 | 0.2092 | 0.1174 | 0.0298 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 699 | 471 | | 4304 | 9250 | 675.2 | 100.28 | 112.63 | 227.13 | 526 | 609 | 656 | 678 | 694 | 707 | 722 | 740 | 781 | 0.0782 | 723 | 1.058 | 105.04 | 31.11 | 1 | 0.0602 | 259 | 0.0017 | 29.52 | 6.816 | 0.2429 | 465980.0 | 327000000 | 234000000000 | 169000000000000 | 0.4313 | 0.2103 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0028 | 0.0000 | 0.0204 | 0.0139 | 0.0353 | 0.0238 | 0.0311 | 0.0120 | 0.0487 | 0.0205 | 0.8609 | 0.9297 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0149 | 0.0139 | 0.0259 | 0.0238 | 0.0191 | 0.0120 | 0.0254 | 0.0205 | 0.9130 | 0.9297 | 0.0082 | 0.0000 | 0.0163 | 0.0000 | 0.0245 | 0.0000 | 0.0367 | 0.0000 | 0.0816 | 0.0000 | 0.0857 | 0.0000 | 0.0816 | 0.0000 | 0.1143 | 0.0000 | 0.5510 | 0.0000 | 0.0004 | 0.0015 | 0.0038 | 0.0128 | 0.0342 | 0.0556 | 0.0680 | 0.0992 | 0.7244 | 8 | 10 | 12 | 14 | 17 | 26 | 59 | 148 | 341 | 0.1976 | 21.25 | 3.579 | 0.6813 | 64269.9 | 61100000 | 74500000000 | 106000000000000 | 0.4869 | 0.1485 | 0.0430 | 0.0000 | 0.1471 | 0.0171 | 0.1991 | 0.0910 | 0.1222 | 0.1229 | 0.1357 | 0.1456 | 0.1154 | 0.1581 | 0.1086 | 0.1229 | 0.0633 | 0.1024 | 0.0656 | 0.2400 | 0.0000 | 0.0000 | 0.0008 | 0.0004 | 0.0013 | 0.0011 | 0.0109 | 0.0094 | 0.0419 | 0.0410 | 0.0747 | 0.0556 | 0.0516 | 0.0402 | 0.0763 | 0.0676 | 0.7425 | 0.7847 | 0.0000 | 0.0006 | 0.0010 | 0.0022 | 0.0031 | 0.0028 | 0.0175 | 0.0185 | 0.0577 | 0.0612 | 0.0911 | 0.1021 | 0.0695 | 0.0606 | 0.0901 | 0.0948 | 0.6699 | 0.6571 | 0.0000 | 0.0009 | 0.0032 | 0.0125 | 0.0529 | 0.0779 | 0.0682 | 0.0904 | 0.6939 | ||
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 744 | 960 | | 1387 | 3556 | 629.5 | 191.17 | 8.12 | 2.69 | 392 | 452 | 506 | 568 | 633 | 689 | 744 | 805 | 887 | 0.1018 | 362 | 0.912 | 64.03 | 21.95 | 1 | 0.1327 | 184 | 0.0012 | 48.33 | 6.819 | 0.1637 | 432781.0 | 318000000 | 246000000000 | 199000000000000 | 0.4120 | 0.2104 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0017 | 0.0009 | 0.0325 | 0.0035 | 0.0959 | 0.0451 | 0.1935 | 0.0911 | 0.1336 | 0.0539 | 0.1781 | 0.0955 | 0.3647 | 0.7091 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0051 | 0.0008 | 0.0339 | 0.0265 | 0.0749 | 0.0671 | 0.0441 | 0.0265 | 0.0575 | 0.0491 | 0.7844 | 0.8300 | 0.0000 | 0.0000 | 0.0051 | 0.0066 | 0.0128 | 0.0331 | 0.0128 | 0.0795 | 0.0821 | 0.0464 | 0.1000 | 0.1192 | 0.0641 | 0.1457 | 0.1128 | 0.1523 | 0.6103 | 0.4172 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.0542 | 0.0842 | 0.0585 | 0.0899 | 0.7076 | 5 | 6 | 6 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0154 | 10.10 | 4.587 | 0.3257 | 73.1 | 722.744 | 7786.33 | 91072.8 | 0.4504 | 0.1710 | 0.0187 | 0.0017 | 0.0727 | 0.0055 | 0.1602 | 0.0051 | 0.2600 | 0.0301 | 0.2471 | 0.0623 | 0.1641 | 0.1057 | 0.0650 | 0.1978 | 0.0116 | 0.3022 | 0.0006 | 0.2895 | 0.0032 | 0.0000 | 0.0165 | 0.0021 | 0.0277 | 0.0015 | 0.0820 | 0.0134 | 0.1331 | 0.0375 | 0.1781 | 0.0643 | 0.1830 | 0.0972 | 0.2067 | 0.2291 | 0.1697 | 0.5548 | 0.1158 | 0.2444 | 0.1608 | 0.1750 | 0.1533 | 0.1583 | 0.1501 | 0.0944 | 0.1158 | 0.0556 | 0.0975 | 0.0889 | 0.0836 | 0.0694 | 0.0568 | 0.0861 | 0.0665 | 0.0278 | 0.0129 | 0.0378 | 0.0695 | 0.1311 | 0.1684 | 0.1913 | 0.1669 | 0.1396 | 0.0825 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 875 | 62 | | 1334 | 3820 | 91.9 | 21.30 | 105.54 | 80.69 | 68 | 74 | 80 | 85 | 90 | 95 | 100 | 106 | 117 | 0.1102 | 421 | 0.866 | 95.82 | 24.17 | 1 | 0.1807 | 241 | 0.0026 | 28.10 | 6.166 | 0.2282 | 8892.5 | 911642 | 99600000 | 11700000000 | 0.4476 | 0.2105 | 0.0034 | 0.0000 | 0.0056 | 0.0000 | 0.0213 | 0.0048 | 0.0369 | 0.0081 | 0.0884 | 0.0306 | 0.1432 | 0.0564 | 0.1454 | 0.0596 | 0.1946 | 0.0854 | 0.3613 | 0.7550 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0055 | 0.0000 | 0.0157 | 0.0023 | 0.0507 | 0.0235 | 0.1005 | 0.0454 | 0.0811 | 0.0310 | 0.1180 | 0.0613 | 0.6267 | 0.8365 | 0.0419 | 0.0125 | 0.0366 | 0.0375 | 0.0628 | 0.1000 | 0.0785 | 0.1000 | 0.1937 | 0.2125 | 0.2042 | 0.1000 | 0.0628 | 0.0750 | 0.0995 | 0.1375 | 0.2199 | 0.2250 | 0.0016 | 0.0128 | 0.0096 | 0.0465 | 0.1348 | 0.1750 | 0.1236 | 0.1637 | 0.3323 | 28 | 40 | 52 | 68 | 85 | 105 | 126 | 153 | 212 | 0.0130 | 7.64 | 5.068 | 0.4624 | 17649.0 | 4150000 | 1240000000 | 442000000000 | 0.4801 | 0.1727 | 0.0158 | 0.0013 | 0.0706 | 0.0076 | 0.1364 | 0.0297 | 0.1583 | 0.0607 | 0.1754 | 0.1208 | 0.1851 | 0.1720 | 0.1218 | 0.1562 | 0.0938 | 0.1720 | 0.0426 | 0.2796 | 0.0000 | 0.0000 | 0.0021 | 0.0017 | 0.0067 | 0.0050 | 0.0249 | 0.0184 | 0.0716 | 0.0537 | 0.1095 | 0.0910 | 0.0851 | 0.0746 | 0.1183 | 0.1065 | 0.5817 | 0.6491 | 0.0036 | 0.0062 | 0.0099 | 0.0075 | 0.0172 | 0.0249 | 0.0506 | 0.0634 | 0.1112 | 0.1045 | 0.1546 | 0.1505 | 0.1103 | 0.1256 | 0.1338 | 0.1381 | 0.4087 | 0.3794 | 0.0013 | 0.0072 | 0.0118 | 0.0301 | 0.0740 | 0.1382 | 0.0950 | 0.1434 | 0.4990 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 199 | 260 | | 10686 | 24087 | 343.1 | 42.34 | 218.62 | 243.80 | 294 | 309 | 319 | 329 | 339 | 349 | 361 | 376 | 398 | 0.0560 | 1348 | 1.108 | 80.65 | 27.02 | 2 | 0.0188 | 201 | 0.0020 | 20.94 | 6.553 | 0.2495 | 119532.0 | 42300000 | 15200000000 | 5550000000000 | 0.4430 | 0.2105 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0032 | 0.0005 | 0.0194 | 0.0089 | 0.0355 | 0.0176 | 0.0461 | 0.0113 | 0.0755 | 0.0211 | 0.8188 | 0.9407 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0015 | 0.0000 | 0.0114 | 0.0086 | 0.0212 | 0.0159 | 0.0232 | 0.0077 | 0.0352 | 0.0146 | 0.9074 | 0.9532 | 0.0199 | 0.0000 | 0.0385 | 0.0000 | 0.0442 | 0.0000 | 0.0855 | 0.0000 | 0.0954 | 0.0000 | 0.1311 | 0.0000 | 0.1197 | 0.0000 | 0.1211 | 0.0000 | 0.3447 | 0.0000 | 0.0047 | 0.0098 | 0.0155 | 0.0422 | 0.0674 | 0.0986 | 0.1131 | 0.1277 | 0.5211 | 18 | 23 | 29 | 46 | 110 | 198 | 297 | 422 | 589 | 0.0307 | 46.12 | 5.951 | 0.4302 | 107227.0 | 68300000 | 50200000000 | 40800000000000 | 0.5298 | 0.1259 | 0.0245 | 0.0018 | 0.1127 | 0.0149 | 0.2277 | 0.0610 | 0.1750 | 0.0972 | 0.1550 | 0.1809 | 0.1245 | 0.2068 | 0.0732 | 0.1277 | 0.0609 | 0.1204 | 0.0464 | 0.1894 | 0.0000 | 0.0000 | 0.0005 | 0.0002 | 0.0017 | 0.0016 | 0.0077 | 0.0073 | 0.0415 | 0.0338 | 0.0707 | 0.0588 | 0.0495 | 0.0417 | 0.0772 | 0.0625 | 0.7513 | 0.7941 | 0.0004 | 0.0004 | 0.0010 | 0.0016 | 0.0029 | 0.0041 | 0.0139 | 0.0205 | 0.0578 | 0.0653 | 0.0903 | 0.1105 | 0.0763 | 0.0890 | 0.1087 | 0.1110 | 0.6487 | 0.5975 | 0.0001 | 0.0011 | 0.0034 | 0.0105 | 0.0471 | 0.0826 | 0.0615 | 0.0887 | 0.7050 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1107 | 725 | | 3073 | 3969 | 338.0 | 79.28 | 111.41 | 132.27 | 234 | 267 | 290 | 314 | 335 | 356 | 378 | 405 | 441 | 0.1217 | 483 | 1.226 | 141.20 | 63.63 | 1 | 0.1276 | 392 | 0.0012 | 36.06 | 6.918 | 0.1908 | 120541.0 | 45200000 | 17700000000 | 7230000000000 | 0.4322 | 0.2106 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0044 | 0.0000 | 0.0183 | 0.0046 | 0.0759 | 0.0201 | 0.1506 | 0.0466 | 0.1440 | 0.0508 | 0.1849 | 0.0756 | 0.4219 | 0.8019 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0017 | 0.0000 | 0.0079 | 0.0033 | 0.0277 | 0.0147 | 0.0513 | 0.0287 | 0.0484 | 0.0184 | 0.0778 | 0.0277 | 0.7854 | 0.9068 | 0.0033 | 0.0248 | 0.0082 | 0.0124 | 0.0131 | 0.0559 | 0.0784 | 0.1801 | 0.1373 | 0.2236 | 0.2124 | 0.1677 | 0.1193 | 0.1242 | 0.1373 | 0.1118 | 0.2909 | 0.0994 | 0.0007 | 0.0013 | 0.0060 | 0.0219 | 0.0672 | 0.1203 | 0.1110 | 0.1356 | 0.5359 | 12 | 23 | 35 | 48 | 64 | 85 | 116 | 178 | 274 | 0.0254 | 11.05 | 4.985 | 0.5393 | 29902.0 | 13200000 | 7610000000 | 5130000000000 | 0.5025 | 0.1307 | 0.0142 | 0.0010 | 0.0548 | 0.0120 | 0.1258 | 0.0239 | 0.1400 | 0.0658 | 0.1826 | 0.1396 | 0.1562 | 0.1854 | 0.1014 | 0.1206 | 0.1055 | 0.1356 | 0.1197 | 0.3161 | 0.0006 | 0.0000 | 0.0000 | 0.0026 | 0.0019 | 0.0036 | 0.0130 | 0.0104 | 0.0467 | 0.0410 | 0.0746 | 0.0607 | 0.0655 | 0.0524 | 0.0966 | 0.0841 | 0.7010 | 0.7451 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0038 | 0.0043 | 0.0076 | 0.0152 | 0.0725 | 0.0769 | 0.0925 | 0.1073 | 0.0620 | 0.0921 | 0.1115 | 0.1138 | 0.6501 | 0.5894 | 0.0024 | 0.0016 | 0.0041 | 0.0114 | 0.0571 | 0.0702 | 0.0637 | 0.0980 | 0.6914 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 487 | 388 | | 17803 | 45389 | 157.0 | 50.28 | 154.36 | 177.24 | 92 | 114 | 128 | 142 | 155 | 168 | 183 | 200 | 225 | 0.0425 | 1928 | 1.251 | 24.52 | 7.81 | 5 | 0.0033 | 58 | 0.0011 | 27.12 | 7.140 | 0.2383 | 27189.4 | 5090000 | 1010000000 | 213000000000 | 0.4282 | 0.2106 | 0.0016 | 0.0001 | 0.0027 | 0.0011 | 0.0080 | 0.0022 | 0.0288 | 0.0083 | 0.0923 | 0.0292 | 0.1552 | 0.0530 | 0.1536 | 0.0615 | 0.1813 | 0.0892 | 0.3764 | 0.7554 | 0.0006 | 0.0001 | 0.0008 | 0.0008 | 0.0020 | 0.0012 | 0.0062 | 0.0038 | 0.0238 | 0.0118 | 0.0466 | 0.0193 | 0.0520 | 0.0202 | 0.0673 | 0.0299 | 0.8006 | 0.9130 | 0.0028 | 0.0076 | 0.0051 | 0.0076 | 0.0145 | 0.0286 | 0.0373 | 0.0753 | 0.0821 | 0.1201 | 0.1345 | 0.1711 | 0.1117 | 0.1287 | 0.1381 | 0.1368 | 0.4740 | 0.3241 | 0.0009 | 0.0019 | 0.0057 | 0.0186 | 0.0505 | 0.0897 | 0.0859 | 0.1121 | 0.6346 | 13 | 18 | 26 | 47 | 81 | 128 | 193 | 278 | 407 | 0.0395 | 20.75 | 5.394 | 0.5005 | 55240.7 | 27700000 | 16900000000 | 11900000000000 | 0.4247 | 0.2143 | 0.0378 | 0.0014 | 0.1492 | 0.0110 | 0.2622 | 0.0683 | 0.1893 | 0.1171 | 0.1504 | 0.1913 | 0.1095 | 0.1978 | 0.0586 | 0.1383 | 0.0341 | 0.1296 | 0.0088 | 0.1451 | 0.0003 | 0.0002 | 0.0011 | 0.0008 | 0.0022 | 0.0018 | 0.0130 | 0.0095 | 0.0518 | 0.0406 | 0.0919 | 0.0720 | 0.0661 | 0.0535 | 0.0987 | 0.0822 | 0.6750 | 0.7394 | 0.0006 | 0.0006 | 0.0012 | 0.0024 | 0.0051 | 0.0080 | 0.0184 | 0.0254 | 0.0735 | 0.0834 | 0.1248 | 0.1314 | 0.0862 | 0.0949 | 0.1190 | 0.1284 | 0.5712 | 0.5254 | 0.0004 | 0.0015 | 0.0030 | 0.0169 | 0.0596 | 0.1071 | 0.0813 | 0.1092 | 0.6210 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 658 | 168 | | 403 | 1766 | 68.5 | 19.76 | 7.99 | 2.37 | 49 | 53 | 56 | 59 | 63 | 70 | 74 | 85 | 98 | 0.1750 | 309 | 1.167 | 34.83 | 13.34 | 1 | 0.2258 | 91 | 0.0533 | 1.76 | 3.525 | 0.6505 | 5083.4 | 408505 | 35400000 | 3290000000 | 0.4186 | 0.2106 | 0.0050 | 0.0000 | 0.0347 | 0.0029 | 0.1139 | 0.0233 | 0.1139 | 0.0437 | 0.1386 | 0.0962 | 0.1238 | 0.1895 | 0.1386 | 0.1137 | 0.1238 | 0.1429 | 0.2079 | 0.3878 | 0.0034 | 0.0000 | 0.0103 | 0.0000 | 0.0206 | 0.0052 | 0.0412 | 0.0129 | 0.1237 | 0.0722 | 0.1340 | 0.1727 | 0.0790 | 0.0851 | 0.0962 | 0.1134 | 0.4914 | 0.5387 | 0.0112 | 0.0000 | 0.0112 | 0.0000 | 0.0000 | 0.0667 | 0.1236 | 0.2444 | 0.1685 | 0.2222 | 0.2360 | 0.2667 | 0.0787 | 0.0222 | 0.1461 | 0.0667 | 0.2247 | 0.1111 | 0.0000 | 0.0000 | 0.0117 | 0.0526 | 0.1287 | 0.1988 | 0.0877 | 0.1345 | 0.3860 | 5 | 6 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0170 | 10.27 | 4.413 | 0.3266 | 69.5 | 648.007 | 6410.02 | 66817.3 | 0.4806 | 0.1782 | 0.0225 | 0.0013 | 0.0688 | 0.0040 | 0.1865 | 0.0092 | 0.2678 | 0.0257 | 0.2240 | 0.0870 | 0.1502 | 0.1087 | 0.0601 | 0.1963 | 0.0138 | 0.3057 | 0.0063 | 0.2622 | 0.0049 | 0.0000 | 0.0154 | 0.0018 | 0.0561 | 0.0054 | 0.0829 | 0.0127 | 0.1488 | 0.0647 | 0.1715 | 0.0810 | 0.1837 | 0.0906 | 0.2179 | 0.2502 | 0.1187 | 0.4937 | 0.1230 | 0.3869 | 0.2181 | 0.2993 | 0.2645 | 0.1314 | 0.1763 | 0.1314 | 0.1137 | 0.0292 | 0.0650 | 0.0219 | 0.0232 | 0.0000 | 0.0139 | 0.0000 | 0.0023 | 0.0000 | 0.0089 | 0.0445 | 0.0870 | 0.1235 | 0.1966 | 0.2184 | 0.1601 | 0.1235 | 0.0375 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 632 | 107 | | 5692 | 8449 | 461.3 | 114.59 | 81.65 | 147.06 | 324 | 362 | 391 | 418 | 445 | 473 | 513 | 563 | 630 | 0.0921 | 778 | 1.004 | 71.59 | 22.36 | 1 | 0.0293 | 167 | 0.0009 | 39.64 | 7.251 | 0.1882 | 225883.0 | 117000000 | 63800000000 | 36400000000000 | 0.4330 | 0.2108 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0078 | 0.0014 | 0.0210 | 0.0041 | 0.0784 | 0.0255 | 0.1563 | 0.0518 | 0.1327 | 0.0450 | 0.1660 | 0.0713 | 0.4365 | 0.8009 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0023 | 0.0000 | 0.0074 | 0.0007 | 0.0379 | 0.0141 | 0.0737 | 0.0297 | 0.0602 | 0.0251 | 0.0848 | 0.0373 | 0.7332 | 0.8931 | 0.0048 | 0.0043 | 0.0072 | 0.0043 | 0.0096 | 0.0215 | 0.0377 | 0.0667 | 0.0786 | 0.1419 | 0.1195 | 0.1699 | 0.0898 | 0.1548 | 0.0922 | 0.1462 | 0.5605 | 0.2903 | 0.0020 | 0.0075 | 0.0110 | 0.0272 | 0.0745 | 0.0926 | 0.0764 | 0.1068 | 0.6020 | 6 | 8 | 9 | 11 | 14 | 23 | 53 | 116 | 264 | 0.1415 | 20.12 | 4.010 | 0.6235 | 28288.5 | 14800000 | 9450000000 | 6870000000000 | 0.6511 | 0.0624 | 0.0586 | 0.0033 | 0.1302 | 0.0308 | 0.2256 | 0.1156 | 0.1757 | 0.1344 | 0.1952 | 0.1817 | 0.1106 | 0.1762 | 0.0521 | 0.1443 | 0.0282 | 0.1112 | 0.0239 | 0.1024 | 0.0009 | 0.0004 | 0.0035 | 0.0031 | 0.0035 | 0.0046 | 0.0173 | 0.0134 | 0.0658 | 0.0598 | 0.0879 | 0.0854 | 0.0602 | 0.0590 | 0.0974 | 0.0935 | 0.6635 | 0.6808 | 0.0016 | 0.0006 | 0.0005 | 0.0024 | 0.0043 | 0.0024 | 0.0173 | 0.0182 | 0.0758 | 0.0740 | 0.0963 | 0.1099 | 0.0568 | 0.0558 | 0.1034 | 0.1128 | 0.6439 | 0.6240 | 0.0014 | 0.0029 | 0.0043 | 0.0193 | 0.0696 | 0.0904 | 0.0541 | 0.1087 | 0.6491 | ||
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1044 | 317 | | 12277 | 27737 | 337.8 | 80.82 | 126.25 | 196.68 | 245 | 268 | 287 | 306 | 326 | 349 | 374 | 406 | 447 | 0.0408 | 1133 | 1.055 | 137.89 | 53.26 | 1 | 0.0307 | 377 | 0.0011 | 31.32 | 7.089 | 0.2146 | 120627.0 | 45500000 | 18100000000 | 7610000000000 | 0.4436 | 0.2108 | 0.0003 | 0.0000 | 0.0014 | 0.0000 | 0.0075 | 0.0005 | 0.0193 | 0.0028 | 0.0768 | 0.0156 | 0.1399 | 0.0382 | 0.1395 | 0.0401 | 0.1655 | 0.0606 | 0.4499 | 0.8421 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0066 | 0.0003 | 0.0331 | 0.0088 | 0.0616 | 0.0201 | 0.0593 | 0.0159 | 0.0849 | 0.0256 | 0.7518 | 0.9293 | 0.0008 | 0.0082 | 0.0036 | 0.0192 | 0.0097 | 0.0549 | 0.0449 | 0.1152 | 0.1237 | 0.1578 | 0.1556 | 0.1852 | 0.1144 | 0.1221 | 0.1516 | 0.1221 | 0.3957 | 0.2154 | 0.0007 | 0.0024 | 0.0049 | 0.0284 | 0.0649 | 0.1105 | 0.0822 | 0.1107 | 0.5952 | 5 | 7 | 8 | 10 | 13 | 46 | 142 | 252 | 404 | 0.0900 | 13.02 | 4.139 | 0.4903 | 54618.6 | 33500000 | 26000000000 | 23800000000000 | 0.3964 | 0.2554 | 0.0519 | 0.0030 | 0.2024 | 0.0144 | 0.3281 | 0.0926 | 0.1490 | 0.1590 | 0.1211 | 0.2328 | 0.0760 | 0.2176 | 0.0384 | 0.1206 | 0.0256 | 0.0893 | 0.0075 | 0.0708 | 0.0000 | 0.0000 | 0.0002 | 0.0003 | 0.0009 | 0.0006 | 0.0045 | 0.0028 | 0.0333 | 0.0259 | 0.0610 | 0.0514 | 0.0479 | 0.0383 | 0.0731 | 0.0617 | 0.7792 | 0.8190 | 0.0002 | 0.0001 | 0.0001 | 0.0012 | 0.0011 | 0.0016 | 0.0074 | 0.0108 | 0.0452 | 0.0500 | 0.0802 | 0.0994 | 0.0683 | 0.0688 | 0.0954 | 0.1041 | 0.7019 | 0.6639 | 0.0001 | 0.0001 | 0.0005 | 0.0061 | 0.0373 | 0.0712 | 0.0564 | 0.0847 | 0.7437 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 425 | 155 | | 10526 | 21020 | 318.4 | 61.96 | 206.32 | 250.19 | 242 | 266 | 284 | 299 | 314 | 330 | 347 | 369 | 404 | 0.0516 | 1084 | 1.093 | 105.19 | 36.12 | 1 | 0.0249 | 262 | 0.0006 | 81.62 | 7.746 | 0.1363 | 105224.0 | 36000000 | 12800000000 | 4660000000000 | 0.4431 | 0.2108 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0026 | 0.0000 | 0.0134 | 0.0015 | 0.0534 | 0.0127 | 0.1190 | 0.0291 | 0.1293 | 0.0329 | 0.1742 | 0.0536 | 0.5079 | 0.8701 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0007 | 0.0233 | 0.0087 | 0.0553 | 0.0181 | 0.0559 | 0.0145 | 0.0879 | 0.0257 | 0.7716 | 0.9324 | 0.0047 | 0.0280 | 0.0142 | 0.0592 | 0.0272 | 0.0592 | 0.0781 | 0.1526 | 0.1230 | 0.2087 | 0.1715 | 0.2150 | 0.1212 | 0.1277 | 0.1467 | 0.0779 | 0.3134 | 0.0717 | 0.0012 | 0.0020 | 0.0075 | 0.0315 | 0.0817 | 0.1365 | 0.1121 | 0.1303 | 0.4971 | 16 | 20 | 26 | 45 | 90 | 165 | 257 | 379 | 569 | 0.0265 | 51.36 | 6.104 | 0.4177 | 105162.0 | 74300000 | 63500000000 | 62100000000000 | 0.4677 | 0.1545 | 0.0348 | 0.0018 | 0.1515 | 0.0098 | 0.2413 | 0.0665 | 0.1600 | 0.1355 | 0.1658 | 0.1909 | 0.1109 | 0.1899 | 0.0702 | 0.1368 | 0.0428 | 0.1209 | 0.0227 | 0.1479 | 0.0001 | 0.0002 | 0.0006 | 0.0006 | 0.0021 | 0.0007 | 0.0075 | 0.0067 | 0.0513 | 0.0425 | 0.0842 | 0.0699 | 0.0615 | 0.0534 | 0.0927 | 0.0778 | 0.7001 | 0.7481 | 0.0000 | 0.0002 | 0.0017 | 0.0024 | 0.0040 | 0.0065 | 0.0161 | 0.0168 | 0.0672 | 0.0746 | 0.1113 | 0.1207 | 0.0727 | 0.0793 | 0.1113 | 0.1116 | 0.6157 | 0.5879 | 0.0003 | 0.0009 | 0.0029 | 0.0128 | 0.0565 | 0.0983 | 0.0684 | 0.1010 | 0.6588 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 735 | 634 | | 3383 | 13602 | 420.5 | 93.73 | 24.16 | 65.07 | 310 | 345 | 369 | 393 | 413 | 435 | 458 | 483 | 531 | 0.0471 | 641 | 0.708 | 187.75 | 42.58 | 1 | 0.1469 | 497 | 0.0008 | 81.64 | 7.362 | 0.1445 | 185607.0 | 86200000 | 42200000000 | 21900000000000 | 0.4414 | 0.2109 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0048 | 0.0000 | 0.0190 | 0.0000 | 0.0557 | 0.0201 | 0.1348 | 0.0447 | 0.1232 | 0.0352 | 0.1517 | 0.0569 | 0.5108 | 0.8430 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0061 | 0.0000 | 0.0327 | 0.0138 | 0.0779 | 0.0312 | 0.0610 | 0.0204 | 0.0832 | 0.0309 | 0.7391 | 0.9038 | 0.0169 | 0.0000 | 0.0127 | 0.0252 | 0.0465 | 0.0377 | 0.0465 | 0.0755 | 0.1269 | 0.1447 | 0.1882 | 0.1698 | 0.0867 | 0.1195 | 0.1501 | 0.1069 | 0.3256 | 0.3208 | 0.0000 | 0.0050 | 0.0126 | 0.0320 | 0.0961 | 0.1420 | 0.1030 | 0.1470 | 0.4623 | 5 | 6 | 7 | 7 | 9 | 10 | 13 | 19 | 43 | 0.1856 | 1.96 | 2.069 | 0.6343 | 4817.1 | 2540000 | 1750000000 | 1330000000000 | 0.5397 | 0.1164 | 0.0580 | 0.0279 | 0.1116 | 0.0343 | 0.1949 | 0.0594 | 0.2024 | 0.1054 | 0.1741 | 0.1577 | 0.1310 | 0.1758 | 0.0759 | 0.1589 | 0.0387 | 0.1368 | 0.0134 | 0.1438 | 0.0052 | 0.0139 | 0.0041 | 0.0154 | 0.0067 | 0.0198 | 0.0191 | 0.0302 | 0.0479 | 0.0395 | 0.0621 | 0.0552 | 0.0592 | 0.0599 | 0.0943 | 0.0738 | 0.7012 | 0.6922 | 0.0010 | 0.0012 | 0.0035 | 0.0035 | 0.0045 | 0.0104 | 0.0205 | 0.0267 | 0.0730 | 0.0818 | 0.0985 | 0.1021 | 0.0725 | 0.0754 | 0.1151 | 0.1155 | 0.6113 | 0.5833 | 0.0026 | 0.0039 | 0.0039 | 0.0176 | 0.0511 | 0.0815 | 0.0686 | 0.1047 | 0.6662 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 916 | 208 | | 6312 | 22401 | 516.6 | 108.92 | 194.68 | 249.60 | 387 | 432 | 460 | 485 | 506 | 529 | 554 | 590 | 659 | 0.0487 | 1092 | 1.116 | 137.30 | 45.69 | 1 | 0.0535 | 338 | 0.0007 | 69.42 | 7.543 | 0.1440 | 278766.0 | 157000000 | 92800000000 | 57400000000000 | 0.4428 | 0.2109 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0000 | 0.0104 | 0.0019 | 0.0576 | 0.0179 | 0.1165 | 0.0397 | 0.1247 | 0.0358 | 0.1680 | 0.0608 | 0.5208 | 0.8440 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0054 | 0.0008 | 0.0320 | 0.0120 | 0.0592 | 0.0239 | 0.0665 | 0.0194 | 0.0912 | 0.0340 | 0.7446 | 0.9099 | 0.0077 | 0.0096 | 0.0132 | 0.0096 | 0.0252 | 0.0382 | 0.0614 | 0.0669 | 0.1107 | 0.1369 | 0.1590 | 0.2452 | 0.0998 | 0.1051 | 0.1239 | 0.1624 | 0.3991 | 0.2261 | 0.0021 | 0.0045 | 0.0156 | 0.0403 | 0.0904 | 0.1255 | 0.1172 | 0.1321 | 0.4722 | 8 | 11 | 15 | 29 | 79 | 153 | 245 | 373 | 559 | 0.0687 | 42.39 | 5.505 | 0.4513 | 100197.0 | 70500000 | 59900000000 | 58200000000000 | 0.4609 | 0.1681 | 0.0552 | 0.0013 | 0.1678 | 0.0137 | 0.2533 | 0.1058 | 0.1683 | 0.1355 | 0.1438 | 0.1985 | 0.1037 | 0.1961 | 0.0500 | 0.1334 | 0.0302 | 0.1063 | 0.0276 | 0.1095 | 0.0003 | 0.0001 | 0.0002 | 0.0003 | 0.0016 | 0.0011 | 0.0067 | 0.0064 | 0.0528 | 0.0424 | 0.0871 | 0.0742 | 0.0642 | 0.0559 | 0.0943 | 0.0845 | 0.6926 | 0.7352 | 0.0001 | 0.0002 | 0.0007 | 0.0008 | 0.0026 | 0.0047 | 0.0182 | 0.0210 | 0.0633 | 0.0712 | 0.1119 | 0.1303 | 0.0840 | 0.0811 | 0.1128 | 0.1143 | 0.6064 | 0.5764 | 0.0003 | 0.0010 | 0.0028 | 0.0120 | 0.0577 | 0.0977 | 0.0730 | 0.1042 | 0.6513 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1056 | 260 | | 4207 | 15495 | 500.5 | 108.07 | 87.49 | 106.42 | 370 | 405 | 433 | 464 | 493 | 520 | 549 | 587 | 643 | 0.0565 | 876 | 0.989 | 119.87 | 30.61 | 1 | 0.0661 | 278 | 0.0007 | 62.59 | 7.399 | 0.1476 | 262186.0 | 144000000 | 82200000000 | 49100000000000 | 0.4288 | 0.2109 | 0.0004 | 0.0000 | 0.0015 | 0.0000 | 0.0033 | 0.0003 | 0.0164 | 0.0020 | 0.0574 | 0.0191 | 0.1257 | 0.0417 | 0.1374 | 0.0355 | 0.1640 | 0.0528 | 0.4940 | 0.8486 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0015 | 0.0000 | 0.0073 | 0.0012 | 0.0297 | 0.0144 | 0.0559 | 0.0271 | 0.0612 | 0.0163 | 0.0749 | 0.0302 | 0.7681 | 0.9108 | 0.0029 | 0.0000 | 0.0086 | 0.0052 | 0.0187 | 0.0363 | 0.0691 | 0.0777 | 0.1281 | 0.2280 | 0.1727 | 0.1969 | 0.0964 | 0.0829 | 0.1410 | 0.1451 | 0.3626 | 0.2280 | 0.0015 | 0.0035 | 0.0035 | 0.0266 | 0.0693 | 0.1151 | 0.0925 | 0.1231 | 0.5648 | 8 | 11 | 16 | 26 | 43 | 64 | 98 | 150 | 246 | 0.0352 | 15.63 | 5.119 | 0.5277 | 18978.6 | 5860000 | 2150000000 | 885000000000 | 0.5211 | 0.1359 | 0.0214 | 0.0046 | 0.0878 | 0.0160 | 0.1521 | 0.0567 | 0.1383 | 0.0743 | 0.1784 | 0.1350 | 0.1508 | 0.1607 | 0.1196 | 0.1350 | 0.0920 | 0.1405 | 0.0595 | 0.2771 | 0.0007 | 0.0012 | 0.0020 | 0.0016 | 0.0043 | 0.0040 | 0.0126 | 0.0130 | 0.0415 | 0.0366 | 0.0643 | 0.0582 | 0.0519 | 0.0478 | 0.0821 | 0.0687 | 0.7407 | 0.7690 | 0.0005 | 0.0003 | 0.0002 | 0.0013 | 0.0029 | 0.0039 | 0.0170 | 0.0181 | 0.0503 | 0.0629 | 0.0867 | 0.0982 | 0.0697 | 0.0732 | 0.0965 | 0.1166 | 0.6762 | 0.6256 | 0.0004 | 0.0016 | 0.0036 | 0.0126 | 0.0506 | 0.0725 | 0.0620 | 0.0889 | 0.7079 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 951 | 130 | | 6472 | 11634 | 104.2 | 26.74 | 134.36 | 144.55 | 75 | 82 | 88 | 93 | 99 | 106 | 114 | 124 | 140 | 0.0675 | 785 | 1.222 | 77.80 | 31.00 | 1 | 0.0311 | 201 | 0.0033 | 14.98 | 6.074 | 0.2909 | 11575.5 | 1380000 | 176000000 | 24100000000 | 0.4404 | 0.2109 | 0.0008 | 0.0000 | 0.0067 | 0.0000 | 0.0180 | 0.0003 | 0.0355 | 0.0049 | 0.0968 | 0.0225 | 0.1552 | 0.0473 | 0.1791 | 0.0458 | 0.2071 | 0.0729 | 0.3007 | 0.8063 | 0.0002 | 0.0000 | 0.0028 | 0.0000 | 0.0058 | 0.0002 | 0.0154 | 0.0008 | 0.0436 | 0.0128 | 0.0690 | 0.0233 | 0.0790 | 0.0166 | 0.1135 | 0.0378 | 0.6708 | 0.9086 | 0.0078 | 0.0060 | 0.0132 | 0.0302 | 0.0296 | 0.0302 | 0.0685 | 0.0867 | 0.1401 | 0.1512 | 0.1556 | 0.2198 | 0.1222 | 0.1109 | 0.1362 | 0.1431 | 0.3268 | 0.2218 | 0.0014 | 0.0074 | 0.0159 | 0.0337 | 0.0708 | 0.1173 | 0.1045 | 0.1399 | 0.5090 | 11 | 17 | 27 | 47 | 80 | 123 | 170 | 236 | 349 | 0.0095 | 68.36 | 6.495 | 0.3320 | 38946.3 | 15400000 | 7190000000 | 3780000000000 | 0.5106 | 0.1580 | 0.0359 | 0.0011 | 0.1272 | 0.0129 | 0.2289 | 0.0620 | 0.1945 | 0.1073 | 0.1660 | 0.1675 | 0.1137 | 0.2080 | 0.0666 | 0.1442 | 0.0449 | 0.1357 | 0.0224 | 0.1612 | 0.0002 | 0.0000 | 0.0004 | 0.0005 | 0.0036 | 0.0015 | 0.0120 | 0.0079 | 0.0557 | 0.0459 | 0.0946 | 0.0834 | 0.0802 | 0.0594 | 0.1058 | 0.0943 | 0.6476 | 0.7070 | 0.0003 | 0.0013 | 0.0024 | 0.0032 | 0.0089 | 0.0084 | 0.0282 | 0.0316 | 0.0805 | 0.0832 | 0.1194 | 0.1342 | 0.0982 | 0.1048 | 0.1210 | 0.1303 | 0.5413 | 0.5031 | 0.0002 | 0.0014 | 0.0041 | 0.0182 | 0.0668 | 0.1165 | 0.0832 | 0.1178 | 0.5918 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 202 | 300 | | 6785 | 14162 | 73.6 | 17.99 | 128.75 | 204.22 | 55 | 60 | 64 | 67 | 70 | 74 | 78 | 85 | 98 | 0.0703 | 996 | 0.964 | 72.80 | 24.35 | 1 | 0.0280 | 190 | 0.0034 | 16.24 | 6.105 | 0.2850 | 5739.9 | 477688 | 42700000 | 4120000000 | 0.4408 | 0.2110 | 0.0005 | 0.0000 | 0.0039 | 0.0005 | 0.0122 | 0.0021 | 0.0270 | 0.0047 | 0.0766 | 0.0226 | 0.1354 | 0.0389 | 0.1541 | 0.0501 | 0.2125 | 0.0784 | 0.3779 | 0.8028 | 0.0002 | 0.0000 | 0.0015 | 0.0001 | 0.0044 | 0.0000 | 0.0115 | 0.0003 | 0.0412 | 0.0127 | 0.0738 | 0.0228 | 0.0842 | 0.0195 | 0.1337 | 0.0408 | 0.6495 | 0.9038 | 0.0089 | 0.0082 | 0.0124 | 0.0392 | 0.0231 | 0.0351 | 0.0738 | 0.1072 | 0.1120 | 0.1691 | 0.1431 | 0.1794 | 0.1182 | 0.1381 | 0.1476 | 0.1196 | 0.3609 | 0.2041 | 0.0051 | 0.0116 | 0.0260 | 0.0619 | 0.0952 | 0.1284 | 0.1208 | 0.1302 | 0.4208 | 12 | 14 | 16 | 19 | 29 | 64 | 131 | 219 | 365 | 0.0796 | 32.45 | 4.690 | 0.5502 | 58277.5 | 46900000 | 56200000000 | 88300000000000 | 0.5837 | 0.1324 | 0.0408 | 0.0021 | 0.1841 | 0.0191 | 0.2326 | 0.0908 | 0.1830 | 0.1300 | 0.1709 | 0.1990 | 0.1158 | 0.1879 | 0.0364 | 0.1423 | 0.0254 | 0.1147 | 0.0110 | 0.1141 | 0.0008 | 0.0004 | 0.0008 | 0.0017 | 0.0017 | 0.0017 | 0.0080 | 0.0075 | 0.0431 | 0.0368 | 0.0772 | 0.0632 | 0.0574 | 0.0462 | 0.1056 | 0.0896 | 0.7054 | 0.7529 | 0.0008 | 0.0006 | 0.0008 | 0.0020 | 0.0029 | 0.0050 | 0.0130 | 0.0190 | 0.0619 | 0.0781 | 0.1060 | 0.1085 | 0.0824 | 0.0930 | 0.1331 | 0.1355 | 0.5993 | 0.5582 | 0.0000 | 0.0009 | 0.0016 | 0.0108 | 0.0498 | 0.0912 | 0.0683 | 0.1170 | 0.6604 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 337 | 336 | | 436 | 1226 | 74.6 | 15.23 | 8.13 | 2.56 | 60 | 63 | 66 | 68 | 70 | 73 | 77 | 87 | 99 | 0.2047 | 251 | 1.186 | 32.02 | 11.05 | 1 | 0.1904 | 83 | 0.0637 | 1.09 | 3.210 | 0.6546 | 5802.3 | 471400 | 40100000 | 3560000000 | 0.4209 | 0.2111 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0159 | 0.0074 | 0.0349 | 0.0123 | 0.1111 | 0.0539 | 0.1714 | 0.1176 | 0.1270 | 0.1176 | 0.1302 | 0.1544 | 0.4095 | 0.5368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0069 | 0.0280 | 0.0115 | 0.0509 | 0.0413 | 0.0865 | 0.0894 | 0.0789 | 0.0642 | 0.0941 | 0.0917 | 0.6539 | 0.6950 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0128 | 0.1429 | 0.0641 | 0.2500 | 0.0897 | 0.2143 | 0.2821 | 0.1786 | 0.1282 | 0.1071 | 0.1154 | 0.0714 | 0.3077 | 0.0357 | 0.0134 | 0.0067 | 0.0000 | 0.0537 | 0.0872 | 0.1409 | 0.0940 | 0.1208 | 0.4832 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0165 | 10.44 | 4.481 | 0.3254 | 72.6 | 704.432 | 7374.94 | 83019.4 | 0.4958 | 0.1499 | 0.0199 | 0.0010 | 0.0634 | 0.0049 | 0.1793 | 0.0119 | 0.2500 | 0.0415 | 0.2591 | 0.0889 | 0.1612 | 0.1235 | 0.0562 | 0.2075 | 0.0091 | 0.3063 | 0.0018 | 0.2144 | 0.0011 | 0.0000 | 0.0103 | 0.0018 | 0.0411 | 0.0044 | 0.0959 | 0.0176 | 0.1610 | 0.0668 | 0.1826 | 0.0809 | 0.1724 | 0.1161 | 0.2226 | 0.2577 | 0.1130 | 0.4547 | 0.1204 | 0.2880 | 0.1821 | 0.2640 | 0.2006 | 0.1600 | 0.1728 | 0.1280 | 0.1512 | 0.0880 | 0.0895 | 0.0560 | 0.0525 | 0.0160 | 0.0278 | 0.0000 | 0.0031 | 0.0000 | 0.0118 | 0.0485 | 0.1132 | 0.1559 | 0.1529 | 0.1500 | 0.1853 | 0.1250 | 0.0574 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 937 | 413 | | 5991 | 6903 | 259.1 | 63.26 | 108.57 | 152.78 | 186 | 207 | 223 | 238 | 250 | 265 | 282 | 304 | 342 | 0.1114 | 769 | 0.943 | 112.29 | 28.65 | 1 | 0.0444 | 266 | 0.0008 | 62.88 | 7.417 | 0.1517 | 71152.1 | 20700000 | 6420000000 | 2110000000000 | 0.4321 | 0.2113 | 0.0005 | 0.0000 | 0.0011 | 0.0002 | 0.0030 | 0.0004 | 0.0169 | 0.0024 | 0.0651 | 0.0200 | 0.1350 | 0.0503 | 0.1430 | 0.0444 | 0.1793 | 0.0657 | 0.4560 | 0.8167 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0017 | 0.0002 | 0.0065 | 0.0010 | 0.0301 | 0.0128 | 0.0639 | 0.0298 | 0.0612 | 0.0204 | 0.0850 | 0.0356 | 0.7507 | 0.9002 | 0.0047 | 0.0024 | 0.0084 | 0.0095 | 0.0196 | 0.0261 | 0.0673 | 0.0760 | 0.1047 | 0.1283 | 0.1551 | 0.1995 | 0.1075 | 0.1045 | 0.1299 | 0.1330 | 0.4028 | 0.3207 | 0.0008 | 0.0015 | 0.0094 | 0.0297 | 0.0884 | 0.1290 | 0.1027 | 0.1354 | 0.5032 | 11 | 13 | 15 | 17 | 26 | 49 | 103 | 211 | 341 | 0.0743 | 21.34 | 4.592 | 0.5689 | 35125.6 | 15800000 | 8350000000 | 5000000000000 | 0.6509 | 0.0801 | 0.1317 | 0.0068 | 0.3103 | 0.0476 | 0.2351 | 0.1766 | 0.1505 | 0.1929 | 0.0909 | 0.1984 | 0.0313 | 0.1508 | 0.0313 | 0.0761 | 0.0094 | 0.0788 | 0.0094 | 0.0720 | 0.0023 | 0.0020 | 0.0014 | 0.0020 | 0.0045 | 0.0024 | 0.0136 | 0.0129 | 0.0573 | 0.0488 | 0.0741 | 0.0815 | 0.0605 | 0.0521 | 0.1137 | 0.1013 | 0.6726 | 0.6969 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0023 | 0.0138 | 0.0166 | 0.0585 | 0.0603 | 0.0973 | 0.1194 | 0.0713 | 0.0758 | 0.1176 | 0.1361 | 0.6383 | 0.5896 | 0.0005 | 0.0020 | 0.0030 | 0.0114 | 0.0530 | 0.0956 | 0.0624 | 0.1115 | 0.6606 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 750 | 676 | | 11146 | 21855 | 106.6 | 28.30 | 189.51 | 171.91 | 74 | 83 | 90 | 97 | 103 | 110 | 118 | 128 | 143 | 0.0573 | 1252 | 0.886 | 106.10 | 29.53 | 1 | 0.0241 | 269 | 0.0014 | 32.07 | 6.896 | 0.2173 | 12166.0 | 1490000 | 200000000 | 29600000000 | 0.4458 | 0.2114 | 0.0009 | 0.0000 | 0.0026 | 0.0003 | 0.0096 | 0.0013 | 0.0300 | 0.0038 | 0.0861 | 0.0213 | 0.1508 | 0.0508 | 0.1608 | 0.0587 | 0.1819 | 0.0839 | 0.3773 | 0.7799 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0039 | 0.0003 | 0.0101 | 0.0021 | 0.0393 | 0.0133 | 0.0634 | 0.0258 | 0.0685 | 0.0231 | 0.0980 | 0.0366 | 0.7155 | 0.8988 | 0.0018 | 0.0088 | 0.0088 | 0.0164 | 0.0226 | 0.0582 | 0.0647 | 0.1239 | 0.1317 | 0.2010 | 0.1714 | 0.1795 | 0.1183 | 0.1163 | 0.1423 | 0.1277 | 0.3383 | 0.1681 | 0.0014 | 0.0032 | 0.0116 | 0.0332 | 0.0812 | 0.1162 | 0.1018 | 0.1287 | 0.5226 | 16 | 35 | 67 | 103 | 142 | 190 | 249 | 320 | 433 | 0.0120 | 37.39 | 6.296 | 0.3650 | 65463.6 | 30100000 | 16600000000 | 10400000000000 | 0.5497 | 0.1277 | 0.0358 | 0.0017 | 0.1299 | 0.0109 | 0.2197 | 0.0768 | 0.1613 | 0.1097 | 0.1616 | 0.1610 | 0.1328 | 0.1855 | 0.0738 | 0.1385 | 0.0543 | 0.1308 | 0.0308 | 0.1851 | 0.0000 | 0.0000 | 0.0012 | 0.0012 | 0.0025 | 0.0022 | 0.0135 | 0.0090 | 0.0598 | 0.0462 | 0.1069 | 0.0836 | 0.0781 | 0.0656 | 0.1195 | 0.1003 | 0.6185 | 0.6919 | 0.0006 | 0.0002 | 0.0018 | 0.0023 | 0.0045 | 0.0088 | 0.0267 | 0.0326 | 0.0915 | 0.1031 | 0.1477 | 0.1742 | 0.1100 | 0.1208 | 0.1446 | 0.1560 | 0.4726 | 0.4020 | 0.0002 | 0.0008 | 0.0031 | 0.0184 | 0.0746 | 0.1276 | 0.0976 | 0.1359 | 0.5419 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 359 | 542 | | 4621 | 10762 | 146.2 | 33.43 | 222.69 | 177.49 | 107 | 118 | 125 | 134 | 142 | 151 | 161 | 172 | 191 | 0.0783 | 843 | 0.885 | 76.16 | 18.03 | 1 | 0.0390 | 180 | 0.0019 | 23.24 | 6.525 | 0.2373 | 22484.2 | 3640000 | 620000000 | 111000000000 | 0.4346 | 0.2115 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0058 | 0.0002 | 0.0194 | 0.0023 | 0.0890 | 0.0207 | 0.1549 | 0.0458 | 0.1876 | 0.0490 | 0.2146 | 0.0759 | 0.3279 | 0.8061 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0024 | 0.0002 | 0.0059 | 0.0009 | 0.0386 | 0.0147 | 0.0709 | 0.0249 | 0.0768 | 0.0190 | 0.1183 | 0.0332 | 0.6866 | 0.9071 | 0.0061 | 0.0150 | 0.0207 | 0.0187 | 0.0292 | 0.0487 | 0.0901 | 0.1423 | 0.1681 | 0.1723 | 0.1791 | 0.2247 | 0.1108 | 0.1086 | 0.1462 | 0.1236 | 0.2497 | 0.1461 | 0.0009 | 0.0043 | 0.0080 | 0.0326 | 0.0913 | 0.1456 | 0.1210 | 0.1504 | 0.4459 | 44 | 73 | 105 | 144 | 183 | 226 | 275 | 342 | 445 | 0.0015 | 74.52 | 7.246 | 0.2302 | 81090.3 | 40900000 | 26000000000 | 19500000000000 | 0.4630 | 0.1957 | 0.0142 | 0.0014 | 0.0752 | 0.0062 | 0.1565 | 0.0283 | 0.1896 | 0.0627 | 0.1844 | 0.1479 | 0.1697 | 0.2060 | 0.1092 | 0.1512 | 0.0700 | 0.1579 | 0.0312 | 0.2384 | 0.0009 | 0.0003 | 0.0020 | 0.0012 | 0.0062 | 0.0036 | 0.0222 | 0.0121 | 0.0621 | 0.0464 | 0.1076 | 0.0967 | 0.0994 | 0.0695 | 0.1261 | 0.1058 | 0.5735 | 0.6645 | 0.0015 | 0.0019 | 0.0047 | 0.0070 | 0.0174 | 0.0174 | 0.0375 | 0.0557 | 0.0962 | 0.1161 | 0.1535 | 0.1663 | 0.1125 | 0.1199 | 0.1367 | 0.1389 | 0.4401 | 0.3768 | 0.0007 | 0.0043 | 0.0107 | 0.0285 | 0.0859 | 0.1281 | 0.1071 | 0.1381 | 0.4965 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 564 | 834 | | 5735 | 9264 | 386.5 | 90.39 | 113.25 | 134.91 | 287 | 312 | 332 | 351 | 371 | 393 | 423 | 457 | 512 | 0.0955 | 885 | 1.153 | 94.87 | 36.50 | 1 | 0.0424 | 243 | 0.0010 | 39.47 | 7.169 | 0.1888 | 157556.0 | 67800000 | 30700000000 | 14700000000000 | 0.4429 | 0.2115 | 0.0008 | 0.0000 | 0.0019 | 0.0006 | 0.0036 | 0.0017 | 0.0202 | 0.0044 | 0.0679 | 0.0189 | 0.1422 | 0.0466 | 0.1486 | 0.0405 | 0.1705 | 0.0615 | 0.4443 | 0.8259 | 0.0004 | 0.0000 | 0.0011 | 0.0002 | 0.0024 | 0.0009 | 0.0105 | 0.0021 | 0.0358 | 0.0126 | 0.0710 | 0.0308 | 0.0693 | 0.0219 | 0.0813 | 0.0324 | 0.7282 | 0.8991 | 0.0076 | 0.0105 | 0.0123 | 0.0026 | 0.0123 | 0.0211 | 0.0550 | 0.0632 | 0.0920 | 0.1395 | 0.1404 | 0.1447 | 0.0920 | 0.1289 | 0.1262 | 0.1421 | 0.4620 | 0.3474 | 0.0012 | 0.0032 | 0.0097 | 0.0385 | 0.0838 | 0.1187 | 0.0956 | 0.1126 | 0.5367 | 9 | 11 | 13 | 22 | 52 | 96 | 147 | 211 | 309 | 0.0380 | 20.61 | 5.347 | 0.4709 | 31025.6 | 11600000 | 5240000000 | 2690000000000 | 0.6389 | 0.0617 | 0.0305 | 0.0023 | 0.1469 | 0.0170 | 0.2362 | 0.0978 | 0.1627 | 0.1213 | 0.1345 | 0.1582 | 0.0949 | 0.1687 | 0.0983 | 0.1201 | 0.0588 | 0.1125 | 0.0373 | 0.2021 | 0.0005 | 0.0000 | 0.0003 | 0.0002 | 0.0016 | 0.0026 | 0.0128 | 0.0086 | 0.0534 | 0.0432 | 0.0826 | 0.0776 | 0.0631 | 0.0491 | 0.1081 | 0.0918 | 0.6777 | 0.7269 | 0.0000 | 0.0008 | 0.0010 | 0.0008 | 0.0054 | 0.0051 | 0.0217 | 0.0249 | 0.0633 | 0.0785 | 0.1178 | 0.1224 | 0.0796 | 0.0890 | 0.1260 | 0.1383 | 0.5852 | 0.5404 | 0.0000 | 0.0006 | 0.0027 | 0.0183 | 0.0601 | 0.0914 | 0.0787 | 0.1213 | 0.6269 | ||
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1088 | 669 | | 5843 | 18102 | 400.3 | 70.70 | 111.60 | 175.03 | 313 | 337 | 359 | 378 | 396 | 414 | 435 | 460 | 494 | 0.0658 | 1192 | 1.022 | 100.70 | 29.21 | 2 | 0.0419 | 245 | 0.0028 | 13.59 | 6.176 | 0.2930 | 165240.0 | 70300000 | 30800000000 | 13800000000000 | 0.4364 | 0.2115 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0009 | 0.0000 | 0.0101 | 0.0002 | 0.0406 | 0.0147 | 0.0975 | 0.0268 | 0.1026 | 0.0251 | 0.1475 | 0.0400 | 0.5998 | 0.8933 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0004 | 0.0000 | 0.0055 | 0.0002 | 0.0189 | 0.0124 | 0.0447 | 0.0197 | 0.0447 | 0.0124 | 0.0609 | 0.0210 | 0.8245 | 0.9344 | 0.0127 | 0.0259 | 0.0152 | 0.0690 | 0.0279 | 0.0517 | 0.0735 | 0.1552 | 0.1343 | 0.2241 | 0.1901 | 0.1897 | 0.1166 | 0.0948 | 0.1445 | 0.1034 | 0.2852 | 0.0862 | 0.0014 | 0.0032 | 0.0064 | 0.0278 | 0.0642 | 0.1063 | 0.1131 | 0.1302 | 0.5474 | 6 | 8 | 9 | 11 | 17 | 44 | 108 | 202 | 366 | 0.1406 | 16.27 | 4.291 | 0.5900 | 43085.6 | 23700000 | 15800000000 | 12200000000000 | 0.5499 | 0.1047 | 0.0414 | 0.0055 | 0.1545 | 0.0135 | 0.3162 | 0.0897 | 0.1505 | 0.1440 | 0.1222 | 0.2063 | 0.0949 | 0.2123 | 0.0535 | 0.1191 | 0.0384 | 0.0927 | 0.0283 | 0.1171 | 0.0000 | 0.0003 | 0.0002 | 0.0005 | 0.0009 | 0.0011 | 0.0063 | 0.0089 | 0.0455 | 0.0402 | 0.0747 | 0.0668 | 0.0468 | 0.0519 | 0.0788 | 0.0678 | 0.7469 | 0.7626 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0019 | 0.0027 | 0.0123 | 0.0113 | 0.0483 | 0.0583 | 0.0924 | 0.0945 | 0.0621 | 0.0730 | 0.0868 | 0.0995 | 0.6955 | 0.6602 | 0.0000 | 0.0002 | 0.0009 | 0.0078 | 0.0487 | 0.0782 | 0.0567 | 0.0840 | 0.7235 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1182 | 506 | | 5215 | 17071 | 251.9 | 54.05 | 103.06 | 163.53 | 180 | 201 | 217 | 233 | 250 | 266 | 282 | 302 | 327 | 0.0592 | 1011 | 1.075 | 113.14 | 33.02 | 1 | 0.0516 | 269 | 0.0008 | 48.54 | 7.272 | 0.1797 | 66392.4 | 18200000 | 5190000000 | 1520000000000 | 0.4330 | 0.2117 | 0.0006 | 0.0000 | 0.0022 | 0.0000 | 0.0048 | 0.0000 | 0.0275 | 0.0022 | 0.0797 | 0.0138 | 0.1232 | 0.0367 | 0.1331 | 0.0359 | 0.1574 | 0.0648 | 0.4715 | 0.8468 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0077 | 0.0012 | 0.0289 | 0.0106 | 0.0534 | 0.0245 | 0.0530 | 0.0168 | 0.0732 | 0.0315 | 0.7817 | 0.9154 | 0.0029 | 0.0373 | 0.0097 | 0.0683 | 0.0165 | 0.0683 | 0.0584 | 0.1739 | 0.1051 | 0.2050 | 0.1907 | 0.1801 | 0.1430 | 0.1180 | 0.1459 | 0.0745 | 0.3278 | 0.0745 | 0.0004 | 0.0027 | 0.0059 | 0.0212 | 0.0550 | 0.1037 | 0.0923 | 0.1127 | 0.6060 | 8 | 10 | 12 | 14 | 19 | 40 | 88 | 178 | 323 | 0.1315 | 17.54 | 4.370 | 0.5904 | 37361.8 | 20200000 | 13400000000 | 10300000000000 | 0.5718 | 0.1052 | 0.0904 | 0.0025 | 0.2461 | 0.0286 | 0.3176 | 0.1880 | 0.1451 | 0.1835 | 0.0925 | 0.1830 | 0.0641 | 0.1810 | 0.0273 | 0.0847 | 0.0137 | 0.0762 | 0.0032 | 0.0727 | 0.0004 | 0.0000 | 0.0008 | 0.0005 | 0.0013 | 0.0015 | 0.0144 | 0.0131 | 0.0649 | 0.0555 | 0.1011 | 0.0975 | 0.0663 | 0.0604 | 0.0930 | 0.0903 | 0.6578 | 0.6812 | 0.0005 | 0.0005 | 0.0016 | 0.0020 | 0.0060 | 0.0048 | 0.0196 | 0.0218 | 0.0670 | 0.0698 | 0.1097 | 0.1043 | 0.0649 | 0.0698 | 0.0947 | 0.0959 | 0.6360 | 0.6311 | 0.0004 | 0.0010 | 0.0042 | 0.0151 | 0.0692 | 0.1025 | 0.0681 | 0.0903 | 0.6491 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1030 | 874 | | 3673 | 4603 | 174.5 | 51.15 | 215.89 | 185.55 | 121 | 134 | 145 | 155 | 165 | 176 | 189 | 208 | 237 | 0.1288 | 593 | 1.114 | 100.81 | 36.62 | 1 | 0.0719 | 264 | 0.0014 | 45.62 | 6.851 | 0.2136 | 33048.1 | 6890000 | 1610000000 | 426000000000 | 0.4339 | 0.2118 | 0.0005 | 0.0000 | 0.0029 | 0.0003 | 0.0103 | 0.0009 | 0.0275 | 0.0024 | 0.1035 | 0.0323 | 0.1844 | 0.0579 | 0.1540 | 0.0695 | 0.1923 | 0.1040 | 0.3247 | 0.7325 | 0.0004 | 0.0000 | 0.0011 | 0.0003 | 0.0054 | 0.0006 | 0.0098 | 0.0011 | 0.0493 | 0.0198 | 0.0761 | 0.0320 | 0.0692 | 0.0315 | 0.1036 | 0.0546 | 0.6853 | 0.8602 | 0.0042 | 0.0032 | 0.0083 | 0.0288 | 0.0208 | 0.0192 | 0.0554 | 0.1058 | 0.1302 | 0.1827 | 0.1911 | 0.1538 | 0.0817 | 0.1250 | 0.1440 | 0.1410 | 0.3643 | 0.2404 | 0.0033 | 0.0026 | 0.0131 | 0.0328 | 0.0858 | 0.1343 | 0.0878 | 0.1304 | 0.5098 | 21 | 49 | 86 | 127 | 170 | 218 | 276 | 353 | 485 | 0.0039 | 128.55 | 7.024 | 0.2296 | 81028.4 | 39900000 | 23100000000 | 14900000000000 | 0.4728 | 0.1730 | 0.0382 | 0.0006 | 0.1401 | 0.0110 | 0.2051 | 0.0760 | 0.1949 | 0.1098 | 0.1809 | 0.1696 | 0.1121 | 0.1982 | 0.0650 | 0.1404 | 0.0420 | 0.1261 | 0.0217 | 0.1683 | 0.0009 | 0.0004 | 0.0026 | 0.0011 | 0.0035 | 0.0044 | 0.0215 | 0.0139 | 0.0953 | 0.0645 | 0.1156 | 0.1004 | 0.0888 | 0.0751 | 0.1301 | 0.1084 | 0.5417 | 0.6319 | 0.0013 | 0.0042 | 0.0080 | 0.0059 | 0.0195 | 0.0210 | 0.0436 | 0.0470 | 0.1113 | 0.1293 | 0.1482 | 0.1839 | 0.1261 | 0.1167 | 0.1368 | 0.1310 | 0.4051 | 0.3610 | 0.0021 | 0.0016 | 0.0102 | 0.0376 | 0.0950 | 0.1432 | 0.1073 | 0.1266 | 0.4764 |