High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1052 | 727 | | 435 | 10158 | 216.6 | 37.95 | 134.54 | 228.49 | 169 | 184 | 193 | 205 | 215 | 223 | 235 | 249 | 268 | 0.0475 | 483 | 1.039 | 156.49 | 50.48 | 1 | 0.9218 | 401 | 0.0052 | 14.90 | 5.415 | 0.3014 | 48369.5 | 11100000 | 2630000000 | 636000000000 | 0.4349 | 0.2080 | 0.0000 | 0.0000 | 0.0096 | 0.0000 | 0.0096 | 0.0000 | 0.0382 | 0.0047 | 0.1019 | 0.0606 | 0.1656 | 0.0629 | 0.1624 | 0.0606 | 0.1943 | 0.0956 | 0.3185 | 0.7156 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0186 | 0.0023 | 0.0849 | 0.0621 | 0.1088 | 0.0552 | 0.0928 | 0.0437 | 0.1432 | 0.0759 | 0.5517 | 0.7609 | 0.0000 | 0.1667 | 0.0000 | 0.0000 | 0.0635 | 0.1667 | 0.1905 | 0.3333 | 0.1429 | 0.3333 | 0.2540 | 0.0000 | 0.1270 | 0.0000 | 0.0635 | 0.0000 | 0.1587 | 0.0000 | 0.0000 | 0.0095 | 0.0237 | 0.0616 | 0.1754 | 0.1469 | 0.1280 | 0.1801 | 0.2749 | 5 | 7 | 8 | 9 | 11 | 16 | 98 | 264 | 495 | 0.1308 | 20.25 | 3.815 | 0.5357 | 70302.5 | 49000000 | 40900000000 | 40000000000000 | 0.5326 | 0.1283 | 0.0600 | 0.0028 | 0.2086 | 0.0308 | 0.2229 | 0.1413 | 0.2086 | 0.1636 | 0.1400 | 0.2070 | 0.0686 | 0.1930 | 0.0514 | 0.1035 | 0.0371 | 0.0867 | 0.0029 | 0.0713 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0037 | 0.0047 | 0.0269 | 0.0233 | 0.0561 | 0.0472 | 0.0326 | 0.0315 | 0.0668 | 0.0585 | 0.8136 | 0.8348 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0011 | 0.0020 | 0.0049 | 0.0053 | 0.0377 | 0.0422 | 0.0681 | 0.0763 | 0.0518 | 0.0666 | 0.0883 | 0.0849 | 0.7477 | 0.7223 | 0.0000 | 0.0000 | 0.0011 | 0.0029 | 0.0350 | 0.0622 | 0.0404 | 0.0733 | 0.7851 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 213 | 896 | | 3746 | 14440 | 324.0 | 67.68 | 163.52 | 174.35 | 235 | 267 | 288 | 305 | 322 | 340 | 359 | 382 | 414 | 0.0614 | 886 | 1.026 | 90.35 | 31.58 | 1 | 0.0670 | 251 | 0.0007 | 89.85 | 7.502 | 0.1378 | 109544.0 | 38500000 | 14000000000 | 5270000000000 | 0.4313 | 0.2081 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0008 | 0.0143 | 0.0014 | 0.0573 | 0.0161 | 0.1297 | 0.0417 | 0.1481 | 0.0296 | 0.1661 | 0.0735 | 0.4822 | 0.8369 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0052 | 0.0014 | 0.0223 | 0.0128 | 0.0419 | 0.0312 | 0.0461 | 0.0115 | 0.0652 | 0.0325 | 0.8187 | 0.9101 | 0.0015 | 0.0741 | 0.0092 | 0.0556 | 0.0382 | 0.0926 | 0.0947 | 0.1667 | 0.1740 | 0.1852 | 0.1969 | 0.1481 | 0.1191 | 0.0926 | 0.1481 | 0.1111 | 0.2183 | 0.0741 | 0.0000 | 0.0005 | 0.0054 | 0.0264 | 0.0696 | 0.1192 | 0.1154 | 0.1472 | 0.5162 | 13 | 17 | 27 | 55 | 99 | 150 | 212 | 304 | 427 | 0.0207 | 22.64 | 5.797 | 0.4177 | 57133.8 | 26400000 | 14400000000 | 8750000000000 | 0.5240 | 0.1275 | 0.0365 | 0.0012 | 0.1204 | 0.0053 | 0.1762 | 0.0439 | 0.2018 | 0.1082 | 0.1883 | 0.1766 | 0.1249 | 0.1778 | 0.0762 | 0.1466 | 0.0532 | 0.1487 | 0.0224 | 0.1917 | 0.0006 | 0.0004 | 0.0018 | 0.0006 | 0.0042 | 0.0024 | 0.0165 | 0.0138 | 0.0564 | 0.0447 | 0.0762 | 0.0656 | 0.0665 | 0.0531 | 0.0911 | 0.0798 | 0.6869 | 0.7397 | 0.0013 | 0.0013 | 0.0019 | 0.0043 | 0.0055 | 0.0080 | 0.0249 | 0.0268 | 0.0675 | 0.0771 | 0.0949 | 0.1009 | 0.0777 | 0.0746 | 0.0971 | 0.0949 | 0.6292 | 0.6123 | 0.0004 | 0.0022 | 0.0050 | 0.0187 | 0.0604 | 0.0872 | 0.0731 | 0.1006 | 0.6523 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 320 | 667 | | 5012 | 4003 | 144.6 | 31.00 | 256.96 | 210.61 | 110 | 119 | 126 | 133 | 139 | 146 | 155 | 168 | 187 | 0.1699 | 680 | 1.061 | 130.67 | 36.72 | 1 | 0.0599 | 300 | 0.0023 | 22.41 | 6.404 | 0.2450 | 21873.6 | 3470000 | 577000000 | 101000000000 | 0.4357 | 0.2084 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0059 | 0.0000 | 0.0223 | 0.0013 | 0.0711 | 0.0189 | 0.1355 | 0.0456 | 0.1443 | 0.0439 | 0.1875 | 0.0634 | 0.4320 | 0.8269 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0000 | 0.0083 | 0.0004 | 0.0355 | 0.0130 | 0.0649 | 0.0252 | 0.0675 | 0.0144 | 0.0966 | 0.0244 | 0.7237 | 0.9225 | 0.0073 | 0.0036 | 0.0158 | 0.0144 | 0.0280 | 0.0758 | 0.0767 | 0.1516 | 0.1571 | 0.1913 | 0.1705 | 0.1733 | 0.1255 | 0.1264 | 0.1437 | 0.1155 | 0.2753 | 0.1480 | 0.0038 | 0.0080 | 0.0127 | 0.0363 | 0.0930 | 0.1303 | 0.1085 | 0.1567 | 0.4507 | 33 | 63 | 100 | 155 | 208 | 265 | 333 | 424 | 568 | 0.0020 | 118.54 | 7.148 | 0.2176 | 110371.0 | 60900000 | 39200000000 | 28100000000000 | 0.4840 | 0.1833 | 0.0323 | 0.0038 | 0.1232 | 0.0212 | 0.2097 | 0.0613 | 0.2097 | 0.1272 | 0.1730 | 0.1779 | 0.1510 | 0.2059 | 0.0587 | 0.1476 | 0.0293 | 0.1272 | 0.0132 | 0.1279 | 0.0005 | 0.0000 | 0.0055 | 0.0033 | 0.0099 | 0.0087 | 0.0307 | 0.0229 | 0.0823 | 0.0715 | 0.1368 | 0.1227 | 0.1011 | 0.0932 | 0.1293 | 0.1165 | 0.5040 | 0.5611 | 0.0007 | 0.0055 | 0.0045 | 0.0028 | 0.0112 | 0.0148 | 0.0389 | 0.0572 | 0.1243 | 0.1210 | 0.1534 | 0.1681 | 0.1213 | 0.1385 | 0.1445 | 0.1376 | 0.4012 | 0.3546 | 0.0030 | 0.0066 | 0.0156 | 0.0361 | 0.0968 | 0.1437 | 0.1203 | 0.1371 | 0.4408 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 883 | 333 | | 6557 | 23757 | 237.9 | 49.19 | 167.48 | 247.49 | 178 | 194 | 208 | 219 | 232 | 246 | 261 | 279 | 306 | 0.0424 | 1007 | 0.712 | 125.45 | 28.02 | 1 | 0.0450 | 295 | 0.0009 | 51.46 | 7.234 | 0.1754 | 59019.4 | 15300000 | 4100000000 | 1150000000000 | 0.4457 | 0.2085 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0056 | 0.0002 | 0.0195 | 0.0010 | 0.0674 | 0.0163 | 0.1393 | 0.0371 | 0.1433 | 0.0322 | 0.1613 | 0.0570 | 0.4629 | 0.8563 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0061 | 0.0002 | 0.0308 | 0.0103 | 0.0701 | 0.0231 | 0.0660 | 0.0135 | 0.0840 | 0.0266 | 0.7414 | 0.9264 | 0.0026 | 0.0174 | 0.0141 | 0.0208 | 0.0132 | 0.0590 | 0.0695 | 0.1042 | 0.1240 | 0.1979 | 0.1803 | 0.1736 | 0.1152 | 0.1285 | 0.1495 | 0.1250 | 0.3316 | 0.1736 | 0.0013 | 0.0020 | 0.0073 | 0.0295 | 0.0809 | 0.1283 | 0.1037 | 0.1332 | 0.5138 | 10 | 11 | 13 | 15 | 22 | 70 | 185 | 328 | 546 | 0.0818 | 47.97 | 5.085 | 0.5273 | 89297.6 | 63700000 | 53300000000 | 49900000000000 | 0.5956 | 0.0948 | 0.0674 | 0.0040 | 0.2566 | 0.0182 | 0.3191 | 0.1656 | 0.1332 | 0.1895 | 0.1118 | 0.2077 | 0.0683 | 0.1749 | 0.0238 | 0.1020 | 0.0132 | 0.0814 | 0.0066 | 0.0567 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0008 | 0.0079 | 0.0064 | 0.0468 | 0.0389 | 0.0815 | 0.0785 | 0.0589 | 0.0508 | 0.0832 | 0.0748 | 0.7206 | 0.7498 | 0.0003 | 0.0000 | 0.0012 | 0.0024 | 0.0026 | 0.0046 | 0.0111 | 0.0124 | 0.0508 | 0.0535 | 0.0996 | 0.1030 | 0.0647 | 0.0701 | 0.0889 | 0.0964 | 0.6808 | 0.6577 | 0.0001 | 0.0012 | 0.0017 | 0.0109 | 0.0482 | 0.0875 | 0.0665 | 0.0853 | 0.6985 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 828 | 486 | | 14994 | 31048 | 470.7 | 84.93 | 145.23 | 202.56 | 364 | 398 | 424 | 447 | 469 | 490 | 513 | 542 | 583 | 0.0407 | 1265 | 1.143 | 89.20 | 33.84 | 2 | 0.0156 | 234 | 0.0008 | 39.09 | 7.354 | 0.1815 | 228773.0 | 115000000 | 59000000000 | 31200000000000 | 0.4389 | 0.2085 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0020 | 0.0001 | 0.0111 | 0.0005 | 0.0411 | 0.0092 | 0.0890 | 0.0204 | 0.0990 | 0.0211 | 0.1268 | 0.0342 | 0.6308 | 0.9146 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0049 | 0.0001 | 0.0183 | 0.0077 | 0.0417 | 0.0152 | 0.0417 | 0.0114 | 0.0544 | 0.0195 | 0.8381 | 0.9459 | 0.0048 | 0.0278 | 0.0077 | 0.0556 | 0.0191 | 0.1065 | 0.0689 | 0.1991 | 0.1411 | 0.2083 | 0.1689 | 0.1435 | 0.1325 | 0.0694 | 0.1536 | 0.1019 | 0.3033 | 0.0880 | 0.0004 | 0.0009 | 0.0068 | 0.0261 | 0.0682 | 0.1054 | 0.0961 | 0.1216 | 0.5745 | 6 | 8 | 10 | 13 | 30 | 83 | 171 | 296 | 457 | 0.1239 | 27.73 | 4.902 | 0.5414 | 62118.6 | 35000000 | 22900000000 | 16700000000000 | 0.4409 | 0.1994 | 0.0472 | 0.0018 | 0.1760 | 0.0086 | 0.2720 | 0.1069 | 0.1840 | 0.1494 | 0.1220 | 0.1901 | 0.0838 | 0.2070 | 0.0520 | 0.1123 | 0.0355 | 0.0968 | 0.0276 | 0.1271 | 0.0004 | 0.0000 | 0.0002 | 0.0003 | 0.0004 | 0.0005 | 0.0104 | 0.0070 | 0.0419 | 0.0383 | 0.0677 | 0.0587 | 0.0504 | 0.0418 | 0.0695 | 0.0619 | 0.7590 | 0.7915 | 0.0002 | 0.0002 | 0.0013 | 0.0006 | 0.0008 | 0.0007 | 0.0105 | 0.0168 | 0.0580 | 0.0609 | 0.0871 | 0.0932 | 0.0560 | 0.0646 | 0.0902 | 0.0922 | 0.6960 | 0.6707 | 0.0000 | 0.0003 | 0.0015 | 0.0114 | 0.0475 | 0.0781 | 0.0516 | 0.0805 | 0.7292 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 389 | 150 | | 4606 | 15170 | 424.9 | 103.36 | 120.09 | 186.60 | 306 | 339 | 363 | 386 | 408 | 432 | 458 | 507 | 588 | 0.0560 | 850 | 1.111 | 95.13 | 27.89 | 1 | 0.0480 | 221 | 0.0012 | 30.61 | 6.994 | 0.2232 | 191216.0 | 91000000 | 45700000000 | 24100000000000 | 0.4331 | 0.2087 | 0.0004 | 0.0000 | 0.0014 | 0.0005 | 0.0043 | 0.0024 | 0.0159 | 0.0046 | 0.0524 | 0.0246 | 0.1229 | 0.0476 | 0.1175 | 0.0410 | 0.1431 | 0.0659 | 0.5421 | 0.8134 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0027 | 0.0002 | 0.0087 | 0.0013 | 0.0278 | 0.0148 | 0.0578 | 0.0278 | 0.0602 | 0.0168 | 0.0801 | 0.0354 | 0.7618 | 0.9036 | 0.0011 | 0.0118 | 0.0078 | 0.0024 | 0.0111 | 0.0118 | 0.0277 | 0.0729 | 0.0632 | 0.0965 | 0.1164 | 0.1412 | 0.0510 | 0.1529 | 0.0854 | 0.1506 | 0.6364 | 0.3600 | 0.0035 | 0.0025 | 0.0122 | 0.0294 | 0.0704 | 0.1160 | 0.0821 | 0.1013 | 0.5826 | 7 | 9 | 12 | 15 | 24 | 53 | 116 | 205 | 380 | 0.0719 | 21.43 | 4.823 | 0.5539 | 49238.9 | 29200000 | 20700000000 | 16600000000000 | 0.4072 | 0.2209 | 0.0112 | 0.0005 | 0.0637 | 0.0029 | 0.1751 | 0.0280 | 0.2032 | 0.0619 | 0.1751 | 0.1581 | 0.1526 | 0.2116 | 0.1058 | 0.1654 | 0.0702 | 0.1537 | 0.0431 | 0.2180 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0014 | 0.0014 | 0.0111 | 0.0059 | 0.0296 | 0.0273 | 0.0544 | 0.0427 | 0.0464 | 0.0368 | 0.0657 | 0.0505 | 0.7911 | 0.8351 | 0.0010 | 0.0008 | 0.0003 | 0.0006 | 0.0025 | 0.0025 | 0.0113 | 0.0139 | 0.0420 | 0.0541 | 0.0795 | 0.0889 | 0.0566 | 0.0606 | 0.0881 | 0.0878 | 0.7186 | 0.6907 | 0.0004 | 0.0020 | 0.0047 | 0.0105 | 0.0368 | 0.0616 | 0.0504 | 0.0780 | 0.7555 | ||
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1125 | 641 | | 11752 | 25342 | 232.5 | 61.19 | 170.59 | 255.96 | 162 | 186 | 201 | 215 | 228 | 242 | 257 | 278 | 310 | 0.0510 | 1293 | 1.092 | 30.46 | 9.43 | 3 | 0.0062 | 73 | 0.0008 | 52.10 | 7.510 | 0.1713 | 57786.2 | 15300000 | 4280000000 | 1270000000000 | 0.4266 | 0.2087 | 0.0003 | 0.0000 | 0.0011 | 0.0002 | 0.0038 | 0.0004 | 0.0137 | 0.0016 | 0.0570 | 0.0194 | 0.1221 | 0.0376 | 0.1242 | 0.0374 | 0.1725 | 0.0532 | 0.5053 | 0.8503 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0015 | 0.0000 | 0.0056 | 0.0005 | 0.0238 | 0.0113 | 0.0480 | 0.0188 | 0.0513 | 0.0158 | 0.0752 | 0.0235 | 0.7940 | 0.9300 | 0.0039 | 0.0023 | 0.0117 | 0.0081 | 0.0174 | 0.0151 | 0.0516 | 0.0755 | 0.0951 | 0.1231 | 0.1428 | 0.1649 | 0.0872 | 0.1115 | 0.1228 | 0.1161 | 0.4674 | 0.3833 | 0.0018 | 0.0029 | 0.0093 | 0.0250 | 0.0622 | 0.0988 | 0.0949 | 0.1131 | 0.5921 | 9 | 12 | 17 | 32 | 58 | 95 | 152 | 272 | 534 | 0.0689 | 34.29 | 5.267 | 0.5297 | 94612.1 | 77200000 | 75700000000 | 83200000000000 | 0.3585 | 0.3278 | 0.0395 | 0.0012 | 0.1512 | 0.0108 | 0.2256 | 0.0794 | 0.1461 | 0.1072 | 0.1502 | 0.1684 | 0.1169 | 0.1823 | 0.0707 | 0.1281 | 0.0608 | 0.1168 | 0.0390 | 0.2056 | 0.0006 | 0.0003 | 0.0021 | 0.0014 | 0.0038 | 0.0026 | 0.0153 | 0.0136 | 0.0581 | 0.0480 | 0.0869 | 0.0812 | 0.0666 | 0.0586 | 0.0861 | 0.0828 | 0.6805 | 0.7116 | 0.0002 | 0.0007 | 0.0019 | 0.0034 | 0.0056 | 0.0081 | 0.0251 | 0.0236 | 0.0640 | 0.0649 | 0.0941 | 0.0908 | 0.0674 | 0.0685 | 0.0855 | 0.0777 | 0.6563 | 0.6622 | 0.0007 | 0.0013 | 0.0062 | 0.0194 | 0.0623 | 0.0938 | 0.0645 | 0.0859 | 0.6660 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 506 | 842 | | 4164 | 7027 | 174.9 | 56.54 | 178.00 | 147.56 | 112 | 130 | 142 | 152 | 163 | 178 | 195 | 217 | 248 | 0.0992 | 697 | 1.133 | 87.73 | 29.97 | 1 | 0.0531 | 221 | 0.0010 | 60.00 | 7.142 | 0.1752 | 33770.8 | 7210000 | 1700000000 | 440000000000 | 0.4464 | 0.2087 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0141 | 0.0006 | 0.0522 | 0.0044 | 0.1370 | 0.0397 | 0.1936 | 0.0823 | 0.1921 | 0.0887 | 0.1775 | 0.1264 | 0.2301 | 0.6580 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0116 | 0.0021 | 0.0475 | 0.0234 | 0.0857 | 0.0412 | 0.0834 | 0.0368 | 0.1113 | 0.0577 | 0.6565 | 0.8388 | 0.0031 | 0.0022 | 0.0021 | 0.0153 | 0.0073 | 0.0131 | 0.0636 | 0.1160 | 0.1366 | 0.1751 | 0.1783 | 0.2079 | 0.1220 | 0.1072 | 0.1689 | 0.1379 | 0.3180 | 0.2254 | 0.0011 | 0.0006 | 0.0034 | 0.0311 | 0.0911 | 0.1324 | 0.1046 | 0.1414 | 0.4943 | 27 | 50 | 74 | 106 | 140 | 178 | 225 | 292 | 389 | 0.0022 | 67.53 | 7.034 | 0.2591 | 53457.0 | 21400000 | 10400000000 | 5770000000000 | 0.4709 | 0.1839 | 0.0246 | 0.0021 | 0.1054 | 0.0050 | 0.2141 | 0.0504 | 0.1742 | 0.0881 | 0.1708 | 0.1448 | 0.1351 | 0.1725 | 0.0799 | 0.1469 | 0.0654 | 0.1452 | 0.0306 | 0.2451 | 0.0003 | 0.0007 | 0.0014 | 0.0000 | 0.0041 | 0.0026 | 0.0151 | 0.0086 | 0.0704 | 0.0509 | 0.1194 | 0.0961 | 0.0898 | 0.0692 | 0.1292 | 0.1056 | 0.5703 | 0.6664 | 0.0022 | 0.0022 | 0.0035 | 0.0049 | 0.0101 | 0.0121 | 0.0321 | 0.0351 | 0.0981 | 0.1185 | 0.1438 | 0.1580 | 0.1130 | 0.0971 | 0.1328 | 0.1377 | 0.4644 | 0.4344 | 0.0004 | 0.0028 | 0.0042 | 0.0276 | 0.0850 | 0.1324 | 0.0967 | 0.1328 | 0.5181 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 182 | 324 | | 4862 | 8847 | 382.1 | 46.56 | 84.31 | 223.89 | 321 | 348 | 363 | 376 | 385 | 395 | 406 | 419 | 440 | 0.0849 | 751 | 0.869 | 141.40 | 42.45 | 2 | 0.0755 | 367 | 0.0020 | 27.89 | 6.580 | 0.2423 | 148135.0 | 58200000 | 23200000000 | 9310000000000 | 0.4327 | 0.2087 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0044 | 0.0000 | 0.0215 | 0.0134 | 0.0430 | 0.0245 | 0.0423 | 0.0117 | 0.0642 | 0.0210 | 0.8233 | 0.9294 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0153 | 0.0134 | 0.0306 | 0.0245 | 0.0237 | 0.0117 | 0.0317 | 0.0210 | 0.8966 | 0.9294 | 0.0214 | 0.0000 | 0.0856 | 0.0000 | 0.1016 | 0.0000 | 0.1283 | 0.0000 | 0.1176 | 0.0000 | 0.1444 | 0.0000 | 0.1016 | 0.0000 | 0.1123 | 0.0000 | 0.1872 | 0.0000 | 0.0019 | 0.0049 | 0.0106 | 0.0314 | 0.0538 | 0.0947 | 0.0981 | 0.1163 | 0.5883 | 8 | 9 | 11 | 12 | 13 | 15 | 20 | 43 | 199 | 0.1434 | 6.44 | 2.531 | 0.5616 | 57228.9 | 60400000 | 73600000000 | 96900000000000 | 0.7057 | 0.0462 | 0.0466 | 0.0000 | 0.0975 | 0.0157 | 0.2458 | 0.0747 | 0.1144 | 0.1041 | 0.1653 | 0.1434 | 0.1483 | 0.1945 | 0.1102 | 0.1611 | 0.0466 | 0.1336 | 0.0254 | 0.1729 | 0.0007 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0048 | 0.0144 | 0.0133 | 0.0390 | 0.0387 | 0.0787 | 0.0678 | 0.0568 | 0.0599 | 0.1026 | 0.0998 | 0.7066 | 0.7145 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0016 | 0.0009 | 0.0122 | 0.0192 | 0.0636 | 0.0603 | 0.0865 | 0.0857 | 0.0530 | 0.0594 | 0.1117 | 0.0970 | 0.6713 | 0.6740 | 0.0000 | 0.0008 | 0.0023 | 0.0129 | 0.0530 | 0.0802 | 0.0560 | 0.1104 | 0.6846 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1211 | 757 | | 6987 | 17413 | 330.1 | 42.49 | 131.75 | 174.14 | 277 | 295 | 309 | 320 | 331 | 341 | 352 | 366 | 384 | 0.0637 | 1110 | 0.875 | 72.84 | 16.16 | 1 | 0.0238 | 166 | 0.0022 | 16.55 | 6.447 | 0.2611 | 110777.0 | 37800000 | 13100000000 | 4580000000000 | 0.4400 | 0.2087 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0062 | 0.0000 | 0.0213 | 0.0109 | 0.0321 | 0.0178 | 0.0485 | 0.0100 | 0.0745 | 0.0186 | 0.8160 | 0.9427 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0000 | 0.0128 | 0.0109 | 0.0169 | 0.0178 | 0.0198 | 0.0095 | 0.0305 | 0.0166 | 0.9167 | 0.9453 | 0.0122 | 0.0000 | 0.0389 | 1.0000 | 0.0681 | 0.0000 | 0.1387 | 0.0000 | 0.1363 | 0.0000 | 0.1533 | 0.0000 | 0.1314 | 0.0000 | 0.1265 | 0.0000 | 0.1946 | 0.0000 | 0.0017 | 0.0047 | 0.0111 | 0.0255 | 0.0505 | 0.0813 | 0.0921 | 0.1160 | 0.6171 | 11 | 14 | 16 | 20 | 45 | 85 | 148 | 242 | 391 | 0.0761 | 18.56 | 4.883 | 0.5466 | 47679.7 | 24000000 | 14300000000 | 9510000000000 | 0.5710 | 0.1004 | 0.0354 | 0.0022 | 0.1286 | 0.0170 | 0.1973 | 0.0815 | 0.1517 | 0.1130 | 0.1402 | 0.1735 | 0.1156 | 0.1590 | 0.0860 | 0.1101 | 0.0744 | 0.1093 | 0.0708 | 0.2342 | 0.0002 | 0.0003 | 0.0005 | 0.0013 | 0.0017 | 0.0015 | 0.0103 | 0.0083 | 0.0444 | 0.0392 | 0.0713 | 0.0616 | 0.0547 | 0.0447 | 0.0799 | 0.0686 | 0.7370 | 0.7746 | 0.0002 | 0.0007 | 0.0022 | 0.0016 | 0.0044 | 0.0034 | 0.0156 | 0.0158 | 0.0577 | 0.0657 | 0.0944 | 0.1062 | 0.0716 | 0.0725 | 0.0954 | 0.1069 | 0.6586 | 0.6274 | 0.0004 | 0.0009 | 0.0034 | 0.0130 | 0.0497 | 0.0852 | 0.0639 | 0.0887 | 0.6949 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 209 | 861 | | 543 | 4357 | 152.9 | 32.22 | 90.49 | 146.81 | 112 | 125 | 134 | 144 | 152 | 161 | 170 | 181 | 194 | 0.0925 | 403 | 1.074 | 82.81 | 25.61 | 1 | 0.3665 | 199 | 0.0040 | 21.07 | 5.680 | 0.2454 | 24410.0 | 4050000 | 697000000 | 124000000000 | 0.4295 | 0.2088 | 0.0000 | 0.0000 | 0.0029 | 0.0000 | 0.0029 | 0.0000 | 0.0632 | 0.0078 | 0.1523 | 0.0447 | 0.1638 | 0.0953 | 0.1868 | 0.0700 | 0.1782 | 0.1498 | 0.2500 | 0.6323 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0000 | 0.0000 | 0.0156 | 0.0075 | 0.0690 | 0.0413 | 0.0980 | 0.0732 | 0.0802 | 0.0450 | 0.1114 | 0.0994 | 0.6236 | 0.7336 | 0.0198 | 0.0000 | 0.0099 | 0.0000 | 0.0891 | 0.1053 | 0.1089 | 0.3684 | 0.1782 | 0.3684 | 0.1188 | 0.0526 | 0.1584 | 0.1053 | 0.1386 | 0.0000 | 0.1782 | 0.0000 | 0.0000 | 0.0075 | 0.0491 | 0.0340 | 0.1132 | 0.1208 | 0.1094 | 0.1245 | 0.4415 | 6 | 7 | 9 | 10 | 12 | 26 | 64 | 155 | 335 | 0.1505 | 5.85 | 3.608 | 0.6197 | 29737.3 | 12900000 | 6260000000 | 3270000000000 | 0.5075 | 0.1310 | 0.0714 | 0.0045 | 0.1939 | 0.0201 | 0.2041 | 0.0447 | 0.2857 | 0.1029 | 0.1276 | 0.2282 | 0.0867 | 0.2371 | 0.0255 | 0.1365 | 0.0051 | 0.1275 | 0.0000 | 0.0984 | 0.0016 | 0.0014 | 0.0008 | 0.0000 | 0.0016 | 0.0007 | 0.0195 | 0.0114 | 0.0568 | 0.0549 | 0.0860 | 0.0834 | 0.0543 | 0.0499 | 0.0933 | 0.0848 | 0.6861 | 0.7135 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0031 | 0.0145 | 0.0157 | 0.0685 | 0.0680 | 0.0858 | 0.0931 | 0.0559 | 0.0596 | 0.1022 | 0.1004 | 0.6702 | 0.6600 | 0.0009 | 0.0000 | 0.0027 | 0.0089 | 0.0608 | 0.0956 | 0.0536 | 0.0903 | 0.6872 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 456 | 893 | | 7298 | 7323 | 187.1 | 41.22 | 216.83 | 133.57 | 140 | 153 | 163 | 172 | 181 | 191 | 203 | 217 | 241 | 0.1269 | 929 | 1.120 | 100.70 | 34.44 | 2 | 0.0340 | 248 | 0.0013 | 39.38 | 6.942 | 0.1916 | 36690.8 | 7560000 | 1640000000 | 376000000000 | 0.4324 | 0.2088 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0047 | 0.0003 | 0.0179 | 0.0010 | 0.0803 | 0.0227 | 0.1350 | 0.0383 | 0.1477 | 0.0424 | 0.1875 | 0.0685 | 0.4263 | 0.8267 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0059 | 0.0001 | 0.0393 | 0.0136 | 0.0647 | 0.0208 | 0.0718 | 0.0167 | 0.1034 | 0.0300 | 0.7137 | 0.9187 | 0.0101 | 0.0100 | 0.0135 | 0.0376 | 0.0262 | 0.0526 | 0.0760 | 0.1153 | 0.1529 | 0.1980 | 0.1782 | 0.1930 | 0.1275 | 0.1454 | 0.1579 | 0.1103 | 0.2576 | 0.1378 | 0.0021 | 0.0043 | 0.0092 | 0.0374 | 0.0860 | 0.1310 | 0.1127 | 0.1396 | 0.4776 | 63 | 92 | 126 | 158 | 191 | 228 | 275 | 332 | 409 | 0.0011 | 78.81 | 7.283 | 0.1845 | 64856.6 | 23800000 | 10100000000 | 4840000000000 | 0.5256 | 0.1334 | 0.0183 | 0.0013 | 0.0889 | 0.0097 | 0.2296 | 0.0405 | 0.1967 | 0.0866 | 0.1778 | 0.1704 | 0.1364 | 0.2228 | 0.0944 | 0.1556 | 0.0384 | 0.1403 | 0.0195 | 0.1729 | 0.0015 | 0.0002 | 0.0025 | 0.0028 | 0.0091 | 0.0054 | 0.0269 | 0.0191 | 0.0793 | 0.0611 | 0.1299 | 0.1025 | 0.1089 | 0.0860 | 0.1316 | 0.1112 | 0.5104 | 0.6118 | 0.0033 | 0.0033 | 0.0066 | 0.0076 | 0.0166 | 0.0239 | 0.0439 | 0.0631 | 0.1159 | 0.1430 | 0.1718 | 0.1816 | 0.1308 | 0.1294 | 0.1320 | 0.1457 | 0.3791 | 0.3023 | 0.0009 | 0.0060 | 0.0160 | 0.0393 | 0.0978 | 0.1494 | 0.1142 | 0.1324 | 0.4439 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 686 | 761 | | 4278 | 10329 | 575.0 | 101.74 | 209.00 | 348.06 | 451 | 485 | 515 | 540 | 564 | 591 | 619 | 660 | 717 | 0.0947 | 978 | 1.233 | 88.57 | 39.70 | 1 | 0.0570 | 244 | 0.0015 | 26.90 | 6.732 | 0.2213 | 340946.0 | 208000000 | 131000000000 | 85100000000000 | 0.4370 | 0.2089 | 0.0003 | 0.0002 | 0.0016 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0005 | 0.0491 | 0.0165 | 0.1035 | 0.0326 | 0.1032 | 0.0271 | 0.1478 | 0.0398 | 0.5865 | 0.8833 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0005 | 0.0000 | 0.0035 | 0.0002 | 0.0289 | 0.0138 | 0.0516 | 0.0248 | 0.0503 | 0.0145 | 0.0751 | 0.0227 | 0.7893 | 0.9239 | 0.0017 | 0.0000 | 0.0017 | 0.0408 | 0.0166 | 0.0510 | 0.0582 | 0.1633 | 0.1481 | 0.2041 | 0.1681 | 0.2245 | 0.0899 | 0.0714 | 0.1514 | 0.1633 | 0.3644 | 0.0816 | 0.0010 | 0.0000 | 0.0051 | 0.0314 | 0.0663 | 0.1352 | 0.1023 | 0.1180 | 0.5408 | 9 | 10 | 12 | 14 | 19 | 49 | 188 | 394 | 707 | 0.1793 | 74.24 | 4.505 | 0.5801 | 164813.0 | 178000000 | 227000000000 | 323000000000000 | 0.5252 | 0.1228 | 0.1229 | 0.0022 | 0.3301 | 0.0673 | 0.2337 | 0.2076 | 0.1108 | 0.1987 | 0.0723 | 0.2065 | 0.0723 | 0.1358 | 0.0313 | 0.0550 | 0.0193 | 0.0673 | 0.0072 | 0.0595 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0013 | 0.0020 | 0.0041 | 0.0055 | 0.0525 | 0.0486 | 0.0965 | 0.0858 | 0.0600 | 0.0532 | 0.0839 | 0.0776 | 0.7008 | 0.7272 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0014 | 0.0012 | 0.0090 | 0.0196 | 0.0690 | 0.0667 | 0.1063 | 0.1181 | 0.0788 | 0.0895 | 0.1095 | 0.1071 | 0.6259 | 0.5958 | 0.0000 | 0.0003 | 0.0000 | 0.0104 | 0.0509 | 0.1031 | 0.0686 | 0.0961 | 0.6707 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1215 | 861 | | 3007 | 9908 | 716.7 | 136.15 | 119.32 | 267.01 | 537 | 590 | 633 | 674 | 713 | 750 | 795 | 845 | 901 | 0.0779 | 772 | 1.131 | 79.76 | 31.58 | 2 | 0.0725 | 218 | 0.0010 | 52.74 | 7.117 | 0.1610 | 532255.0 | 408000000 | 323000000000 | 262000000000000 | 0.4330 | 0.2090 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0007 | 0.0651 | 0.0200 | 0.1481 | 0.0312 | 0.1456 | 0.0346 | 0.1792 | 0.0481 | 0.4484 | 0.8654 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0007 | 0.0316 | 0.0198 | 0.0643 | 0.0271 | 0.0583 | 0.0218 | 0.0671 | 0.0305 | 0.7723 | 0.9001 | 0.0040 | 0.0588 | 0.0059 | 0.0588 | 0.0198 | 0.0882 | 0.0931 | 0.3529 | 0.1802 | 0.2941 | 0.1842 | 0.0588 | 0.0911 | 0.0294 | 0.1564 | 0.0588 | 0.2653 | 0.0000 | 0.0000 | 0.0007 | 0.0041 | 0.0244 | 0.0807 | 0.1404 | 0.1065 | 0.1303 | 0.5129 | 7 | 9 | 10 | 11 | 13 | 16 | 31 | 132 | 393 | 0.2663 | 40.82 | 3.458 | 0.6732 | 85524.5 | 93100000 | 121000000000 | 174000000000000 | 0.6043 | 0.0864 | 0.1806 | 0.0164 | 0.2843 | 0.1228 | 0.2274 | 0.2439 | 0.1237 | 0.1735 | 0.1304 | 0.1571 | 0.0201 | 0.1489 | 0.0201 | 0.0687 | 0.0134 | 0.0491 | 0.0000 | 0.0196 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0063 | 0.0059 | 0.0680 | 0.0675 | 0.1151 | 0.0990 | 0.0657 | 0.0671 | 0.1024 | 0.0998 | 0.6425 | 0.6607 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0115 | 0.0085 | 0.0781 | 0.0846 | 0.1289 | 0.1455 | 0.0849 | 0.0795 | 0.1226 | 0.1286 | 0.5734 | 0.5516 | 0.0000 | 0.0000 | 0.0010 | 0.0097 | 0.0711 | 0.1178 | 0.0808 | 0.1168 | 0.6027 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 146 | 887 | | 7631 | 21436 | 727.6 | 138.83 | 177.21 | 164.76 | 559 | 609 | 647 | 680 | 711 | 747 | 788 | 842 | 928 | 0.0466 | 999 | 1.151 | 109.39 | 39.66 | 3 | 0.0358 | 273 | 0.0005 | 96.74 | 7.799 | 0.1272 | 548709.0 | 428000000 | 346000000000 | 288000000000000 | 0.4347 | 0.2091 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0098 | 0.0011 | 0.0577 | 0.0148 | 0.1275 | 0.0300 | 0.1226 | 0.0286 | 0.1538 | 0.0479 | 0.5265 | 0.8776 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0040 | 0.0001 | 0.0261 | 0.0111 | 0.0570 | 0.0203 | 0.0558 | 0.0116 | 0.0815 | 0.0188 | 0.7746 | 0.9381 | 0.0024 | 0.0271 | 0.0065 | 0.0226 | 0.0212 | 0.1041 | 0.0637 | 0.1719 | 0.1371 | 0.1900 | 0.1853 | 0.1900 | 0.1273 | 0.1538 | 0.1510 | 0.0860 | 0.3053 | 0.0543 | 0.0020 | 0.0038 | 0.0116 | 0.0358 | 0.0832 | 0.1282 | 0.1170 | 0.1331 | 0.4854 | 19 | 36 | 62 | 97 | 135 | 178 | 225 | 286 | 389 | 0.0094 | 25.15 | 6.072 | 0.3627 | 58546.5 | 27800000 | 17200000000 | 13100000000000 | 0.4795 | 0.1685 | 0.0412 | 0.0013 | 0.1579 | 0.0105 | 0.2563 | 0.0772 | 0.1701 | 0.1359 | 0.1559 | 0.1808 | 0.1097 | 0.2006 | 0.0682 | 0.1460 | 0.0319 | 0.1267 | 0.0087 | 0.1208 | 0.0003 | 0.0003 | 0.0011 | 0.0011 | 0.0045 | 0.0011 | 0.0186 | 0.0128 | 0.0660 | 0.0509 | 0.1297 | 0.1018 | 0.1036 | 0.0883 | 0.1381 | 0.1190 | 0.5381 | 0.6246 | 0.0013 | 0.0031 | 0.0053 | 0.0081 | 0.0151 | 0.0171 | 0.0419 | 0.0463 | 0.0956 | 0.1170 | 0.1640 | 0.1725 | 0.1258 | 0.1325 | 0.1545 | 0.1478 | 0.3965 | 0.3555 | 0.0009 | 0.0027 | 0.0070 | 0.0268 | 0.0857 | 0.1465 | 0.1242 | 0.1468 | 0.4593 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 431 | 339 | | 3943 | 10483 | 650.4 | 93.20 | 77.12 | 134.86 | 524 | 578 | 611 | 637 | 655 | 676 | 697 | 725 | 765 | 0.0630 | 660 | 1.066 | 99.30 | 32.65 | 1 | 0.0621 | 245 | 0.0013 | 29.21 | 6.926 | 0.2389 | 431670.0 | 292000000 | 201000000000 | 140000000000000 | 0.4337 | 0.2092 | 0.0006 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0043 | 0.0003 | 0.0239 | 0.0147 | 0.0347 | 0.0234 | 0.0340 | 0.0127 | 0.0534 | 0.0226 | 0.8476 | 0.9264 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0003 | 0.0148 | 0.0147 | 0.0235 | 0.0234 | 0.0179 | 0.0127 | 0.0277 | 0.0226 | 0.9140 | 0.9264 | 0.0065 | 0.0000 | 0.0065 | 0.0000 | 0.0226 | 0.0000 | 0.0355 | 0.0000 | 0.1000 | 0.0000 | 0.0871 | 0.0000 | 0.1065 | 0.0000 | 0.1290 | 0.0000 | 0.5065 | 0.0000 | 0.0000 | 0.0038 | 0.0072 | 0.0191 | 0.0401 | 0.0558 | 0.0615 | 0.0873 | 0.7252 | 6 | 8 | 9 | 11 | 14 | 22 | 53 | 125 | 238 | 0.1380 | 10.00 | 3.574 | 0.6077 | 24132.5 | 11700000 | 7110000000 | 4930000000000 | 0.4308 | 0.2239 | 0.0546 | 0.0060 | 0.1513 | 0.0313 | 0.2122 | 0.0625 | 0.1912 | 0.1159 | 0.1639 | 0.1915 | 0.1261 | 0.1935 | 0.0630 | 0.1381 | 0.0315 | 0.1190 | 0.0063 | 0.1421 | 0.0010 | 0.0000 | 0.0017 | 0.0015 | 0.0024 | 0.0033 | 0.0102 | 0.0118 | 0.0453 | 0.0386 | 0.0572 | 0.0477 | 0.0437 | 0.0443 | 0.0670 | 0.0641 | 0.7716 | 0.7887 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0020 | 0.0017 | 0.0113 | 0.0139 | 0.0577 | 0.0582 | 0.0658 | 0.0747 | 0.0516 | 0.0595 | 0.0791 | 0.0860 | 0.7313 | 0.7059 | 0.0004 | 0.0000 | 0.0015 | 0.0127 | 0.0470 | 0.0601 | 0.0548 | 0.0660 | 0.7576 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 917 | 765 | | 4787 | 6025 | 134.0 | 29.36 | 199.47 | 144.31 | 101 | 111 | 117 | 124 | 130 | 137 | 145 | 154 | 168 | 0.1200 | 723 | 1.159 | 112.49 | 39.01 | 1 | 0.0570 | 273 | 0.0026 | 20.01 | 6.253 | 0.2547 | 18810.6 | 2780000 | 434000000 | 72000000000 | 0.4427 | 0.2093 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0064 | 0.0013 | 0.0155 | 0.0016 | 0.0709 | 0.0202 | 0.1267 | 0.0377 | 0.1506 | 0.0388 | 0.1815 | 0.0566 | 0.4467 | 0.8438 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0073 | 0.0004 | 0.0405 | 0.0149 | 0.0653 | 0.0246 | 0.0710 | 0.0181 | 0.0965 | 0.0305 | 0.7169 | 0.9114 | 0.0043 | 0.0000 | 0.0157 | 0.0082 | 0.0443 | 0.0286 | 0.0944 | 0.1224 | 0.1688 | 0.1510 | 0.1574 | 0.2041 | 0.0987 | 0.1102 | 0.1273 | 0.1224 | 0.2890 | 0.2531 | 0.0018 | 0.0042 | 0.0125 | 0.0365 | 0.0983 | 0.1347 | 0.1117 | 0.1440 | 0.4564 | 44 | 68 | 100 | 134 | 171 | 211 | 256 | 309 | 392 | 0.0015 | 70.67 | 7.066 | 0.2195 | 60610.6 | 23900000 | 11300000000 | 6160000000000 | 0.5305 | 0.1272 | 0.0202 | 0.0004 | 0.0960 | 0.0047 | 0.2098 | 0.0436 | 0.2030 | 0.0781 | 0.1955 | 0.1872 | 0.1348 | 0.1919 | 0.0851 | 0.1725 | 0.0447 | 0.1552 | 0.0110 | 0.1665 | 0.0006 | 0.0003 | 0.0009 | 0.0005 | 0.0019 | 0.0026 | 0.0206 | 0.0127 | 0.0768 | 0.0560 | 0.1070 | 0.0915 | 0.0989 | 0.0710 | 0.1385 | 0.1099 | 0.5548 | 0.6556 | 0.0015 | 0.0032 | 0.0064 | 0.0097 | 0.0124 | 0.0175 | 0.0500 | 0.0662 | 0.1199 | 0.1364 | 0.1640 | 0.1857 | 0.1189 | 0.1422 | 0.1690 | 0.1513 | 0.3578 | 0.2877 | 0.0008 | 0.0008 | 0.0077 | 0.0291 | 0.0926 | 0.1403 | 0.1170 | 0.1592 | 0.4525 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 503 | 432 | | 11808 | 33332 | 318.9 | 77.36 | 142.89 | 210.03 | 224 | 252 | 274 | 294 | 313 | 332 | 354 | 382 | 421 | 0.0347 | 1158 | 1.075 | 96.88 | 32.00 | 1 | 0.0204 | 241 | 0.0011 | 35.28 | 7.136 | 0.2018 | 107664.0 | 38400000 | 14400000000 | 5670000000000 | 0.4385 | 0.2096 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0068 | 0.0004 | 0.0240 | 0.0021 | 0.0823 | 0.0190 | 0.1435 | 0.0483 | 0.1432 | 0.0507 | 0.1608 | 0.0696 | 0.4388 | 0.8100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0071 | 0.0012 | 0.0317 | 0.0115 | 0.0656 | 0.0250 | 0.0600 | 0.0226 | 0.0788 | 0.0331 | 0.7553 | 0.9064 | 0.0047 | 0.0040 | 0.0064 | 0.0162 | 0.0180 | 0.0324 | 0.0588 | 0.1309 | 0.1171 | 0.1646 | 0.1656 | 0.2146 | 0.1257 | 0.1242 | 0.1416 | 0.1026 | 0.3621 | 0.2105 | 0.0020 | 0.0023 | 0.0069 | 0.0236 | 0.0705 | 0.1235 | 0.0941 | 0.1163 | 0.5608 | 6 | 7 | 9 | 11 | 20 | 67 | 166 | 292 | 458 | 0.1413 | 28.98 | 4.701 | 0.5652 | 64528.1 | 40100000 | 31100000000 | 29500000000000 | 0.4198 | 0.2297 | 0.0409 | 0.0008 | 0.1490 | 0.0130 | 0.2877 | 0.0770 | 0.1876 | 0.1317 | 0.1496 | 0.1991 | 0.0863 | 0.2098 | 0.0489 | 0.1278 | 0.0334 | 0.1018 | 0.0167 | 0.1390 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0007 | 0.0046 | 0.0041 | 0.0332 | 0.0264 | 0.0586 | 0.0502 | 0.0443 | 0.0368 | 0.0677 | 0.0562 | 0.7904 | 0.8252 | 0.0000 | 0.0002 | 0.0003 | 0.0008 | 0.0015 | 0.0014 | 0.0069 | 0.0086 | 0.0446 | 0.0485 | 0.0792 | 0.0935 | 0.0610 | 0.0660 | 0.0897 | 0.0966 | 0.7168 | 0.6842 | 0.0000 | 0.0006 | 0.0008 | 0.0069 | 0.0372 | 0.0677 | 0.0539 | 0.0771 | 0.7557 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 640 | 647 | | 6376 | 20211 | 467.1 | 97.26 | 74.59 | 104.47 | 355 | 384 | 407 | 429 | 451 | 477 | 504 | 541 | 602 | 0.0495 | 1000 | 0.965 | 107.82 | 31.58 | 1 | 0.0402 | 256 | 0.0008 | 48.43 | 7.332 | 0.1727 | 227685.0 | 116000000 | 61700000000 | 34200000000000 | 0.4323 | 0.2096 | 0.0005 | 0.0000 | 0.0005 | 0.0002 | 0.0030 | 0.0000 | 0.0118 | 0.0013 | 0.0469 | 0.0161 | 0.0999 | 0.0336 | 0.1154 | 0.0239 | 0.1501 | 0.0351 | 0.5720 | 0.8897 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0063 | 0.0002 | 0.0211 | 0.0111 | 0.0446 | 0.0196 | 0.0504 | 0.0108 | 0.0759 | 0.0166 | 0.7993 | 0.9416 | 0.0039 | 0.0000 | 0.0068 | 0.0084 | 0.0193 | 0.0169 | 0.0501 | 0.0478 | 0.1157 | 0.1348 | 0.1533 | 0.1573 | 0.0984 | 0.1152 | 0.1215 | 0.1348 | 0.4311 | 0.3848 | 0.0004 | 0.0014 | 0.0086 | 0.0280 | 0.0714 | 0.1288 | 0.1065 | 0.1352 | 0.5197 | 7 | 8 | 9 | 11 | 16 | 39 | 83 | 140 | 227 | 0.1404 | 11.27 | 4.303 | 0.6000 | 16476.9 | 5110000 | 1900000000 | 803000000000 | 0.4799 | 0.1508 | 0.0373 | 0.0004 | 0.1664 | 0.0126 | 0.2806 | 0.0605 | 0.1730 | 0.1438 | 0.1498 | 0.2138 | 0.1068 | 0.2197 | 0.0397 | 0.1363 | 0.0281 | 0.1023 | 0.0182 | 0.1106 | 0.0003 | 0.0001 | 0.0003 | 0.0006 | 0.0006 | 0.0010 | 0.0070 | 0.0080 | 0.0388 | 0.0338 | 0.0642 | 0.0584 | 0.0456 | 0.0429 | 0.0655 | 0.0588 | 0.7778 | 0.7963 | 0.0000 | 0.0010 | 0.0005 | 0.0002 | 0.0012 | 0.0013 | 0.0093 | 0.0155 | 0.0514 | 0.0530 | 0.0784 | 0.0890 | 0.0588 | 0.0718 | 0.0916 | 0.0918 | 0.7088 | 0.6764 | 0.0000 | 0.0000 | 0.0019 | 0.0069 | 0.0418 | 0.0702 | 0.0519 | 0.0787 | 0.7487 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1093 | 541 | | 6510 | 19083 | 329.3 | 67.71 | 96.25 | 108.79 | 246 | 270 | 288 | 306 | 322 | 340 | 362 | 390 | 424 | 0.0512 | 978 | 1.154 | 97.62 | 37.11 | 1 | 0.0393 | 256 | 0.0013 | 28.44 | 6.892 | 0.2102 | 112993.0 | 40300000 | 14900000000 | 5720000000000 | 0.4415 | 0.2097 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0043 | 0.0003 | 0.0149 | 0.0014 | 0.0652 | 0.0158 | 0.1269 | 0.0341 | 0.1409 | 0.0340 | 0.1777 | 0.0597 | 0.4684 | 0.8547 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0018 | 0.0000 | 0.0065 | 0.0002 | 0.0277 | 0.0116 | 0.0554 | 0.0212 | 0.0606 | 0.0158 | 0.0862 | 0.0306 | 0.7611 | 0.9207 | 0.0042 | 0.0157 | 0.0067 | 0.0000 | 0.0177 | 0.0627 | 0.0725 | 0.1412 | 0.1197 | 0.1961 | 0.1594 | 0.1843 | 0.1197 | 0.1451 | 0.1476 | 0.1451 | 0.3524 | 0.1098 | 0.0013 | 0.0033 | 0.0086 | 0.0309 | 0.0800 | 0.1165 | 0.1009 | 0.1201 | 0.5385 | 7 | 9 | 12 | 27 | 55 | 86 | 127 | 179 | 256 | 0.0642 | 12.35 | 5.075 | 0.5282 | 21099.1 | 6350000 | 2360000000 | 1030000000000 | 0.4788 | 0.1572 | 0.0140 | 0.0020 | 0.0726 | 0.0070 | 0.1767 | 0.0276 | 0.1707 | 0.0700 | 0.1712 | 0.1521 | 0.1612 | 0.1785 | 0.0996 | 0.1459 | 0.0776 | 0.1537 | 0.0566 | 0.2631 | 0.0004 | 0.0001 | 0.0007 | 0.0005 | 0.0036 | 0.0013 | 0.0080 | 0.0073 | 0.0353 | 0.0283 | 0.0641 | 0.0499 | 0.0529 | 0.0434 | 0.0741 | 0.0687 | 0.7611 | 0.8004 | 0.0005 | 0.0002 | 0.0015 | 0.0007 | 0.0028 | 0.0046 | 0.0118 | 0.0137 | 0.0486 | 0.0587 | 0.0819 | 0.0869 | 0.0679 | 0.0845 | 0.1039 | 0.1128 | 0.6810 | 0.6378 | 0.0004 | 0.0006 | 0.0017 | 0.0103 | 0.0404 | 0.0685 | 0.0604 | 0.0855 | 0.7323 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 799 | 497 | | 16816 | 24748 | 122.3 | 34.96 | 236.76 | 206.30 | 82 | 94 | 102 | 110 | 118 | 126 | 136 | 149 | 168 | 0.0650 | 1609 | 1.118 | 72.20 | 25.02 | 3 | 0.0108 | 181 | 0.0021 | 18.82 | 6.539 | 0.2763 | 16190.9 | 2320000 | 358000000 | 60000000000 | 0.4389 | 0.2098 | 0.0010 | 0.0001 | 0.0025 | 0.0003 | 0.0091 | 0.0014 | 0.0328 | 0.0040 | 0.0891 | 0.0250 | 0.1521 | 0.0565 | 0.1545 | 0.0597 | 0.1758 | 0.0901 | 0.3831 | 0.7630 | 0.0004 | 0.0001 | 0.0005 | 0.0000 | 0.0026 | 0.0002 | 0.0095 | 0.0013 | 0.0356 | 0.0130 | 0.0650 | 0.0262 | 0.0618 | 0.0238 | 0.0849 | 0.0395 | 0.7396 | 0.8959 | 0.0031 | 0.0096 | 0.0075 | 0.0071 | 0.0173 | 0.0199 | 0.0537 | 0.1065 | 0.1221 | 0.1508 | 0.1553 | 0.2060 | 0.1205 | 0.1232 | 0.1477 | 0.1521 | 0.3728 | 0.2246 | 0.0013 | 0.0031 | 0.0088 | 0.0298 | 0.0749 | 0.1135 | 0.0977 | 0.1296 | 0.5413 | 21 | 45 | 86 | 134 | 187 | 246 | 312 | 397 | 532 | 0.0053 | 78.87 | 7.190 | 0.2785 | 98609.0 | 53500000 | 34300000000 | 24800000000000 | 0.5106 | 0.1669 | 0.0256 | 0.0012 | 0.1110 | 0.0083 | 0.2322 | 0.0422 | 0.1927 | 0.1005 | 0.1604 | 0.1805 | 0.1290 | 0.2104 | 0.0825 | 0.1584 | 0.0439 | 0.1366 | 0.0227 | 0.1620 | 0.0004 | 0.0002 | 0.0009 | 0.0012 | 0.0050 | 0.0019 | 0.0154 | 0.0099 | 0.0609 | 0.0492 | 0.1064 | 0.0949 | 0.0889 | 0.0752 | 0.1192 | 0.1063 | 0.6028 | 0.6612 | 0.0004 | 0.0013 | 0.0032 | 0.0039 | 0.0100 | 0.0142 | 0.0294 | 0.0412 | 0.0896 | 0.1025 | 0.1454 | 0.1529 | 0.1084 | 0.1139 | 0.1346 | 0.1366 | 0.4791 | 0.4335 | 0.0001 | 0.0020 | 0.0079 | 0.0209 | 0.0743 | 0.1266 | 0.1001 | 0.1318 | 0.5361 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 787 | 786 | | 14112 | 32367 | 245.5 | 77.16 | 146.77 | 228.26 | 156 | 185 | 205 | 221 | 237 | 254 | 274 | 301 | 345 | 0.0488 | 1581 | 0.669 | 148.12 | 27.73 | 3 | 0.0257 | 363 | 0.0006 | 60.19 | 7.782 | 0.1687 | 66225.0 | 19500000 | 6230000000 | 2150000000000 | 0.4164 | 0.2099 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0068 | 0.0005 | 0.0211 | 0.0043 | 0.0673 | 0.0249 | 0.1414 | 0.0502 | 0.1309 | 0.0527 | 0.1587 | 0.0666 | 0.4724 | 0.8007 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0025 | 0.0003 | 0.0074 | 0.0026 | 0.0218 | 0.0131 | 0.0526 | 0.0251 | 0.0492 | 0.0237 | 0.0741 | 0.0308 | 0.7916 | 0.9043 | 0.0010 | 0.0021 | 0.0033 | 0.0076 | 0.0118 | 0.0125 | 0.0393 | 0.0569 | 0.1035 | 0.1090 | 0.1432 | 0.1444 | 0.0996 | 0.0938 | 0.1288 | 0.1146 | 0.4695 | 0.4590 | 0.0005 | 0.0024 | 0.0074 | 0.0199 | 0.0565 | 0.1073 | 0.0842 | 0.1154 | 0.6063 | 13 | 15 | 17 | 22 | 34 | 66 | 132 | 244 | 448 | 0.0654 | 39.84 | 4.972 | 0.5439 | 73640.4 | 55300000 | 50400000000 | 51700000000000 | 0.5011 | 0.1602 | 0.0623 | 0.0031 | 0.2185 | 0.0242 | 0.2928 | 0.1386 | 0.1538 | 0.1668 | 0.1059 | 0.2014 | 0.0738 | 0.1699 | 0.0455 | 0.1175 | 0.0254 | 0.0808 | 0.0220 | 0.0977 | 0.0000 | 0.0003 | 0.0009 | 0.0002 | 0.0020 | 0.0009 | 0.0125 | 0.0097 | 0.0604 | 0.0529 | 0.0922 | 0.0798 | 0.0683 | 0.0642 | 0.1028 | 0.0895 | 0.6609 | 0.7026 | 0.0001 | 0.0004 | 0.0013 | 0.0019 | 0.0031 | 0.0054 | 0.0184 | 0.0221 | 0.0771 | 0.0786 | 0.1154 | 0.1217 | 0.0827 | 0.0911 | 0.1160 | 0.1245 | 0.5858 | 0.5543 | 0.0004 | 0.0009 | 0.0021 | 0.0159 | 0.0682 | 0.1066 | 0.0762 | 0.1087 | 0.6210 | ||
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1153 | 647 | | 7001 | 25505 | 556.6 | 122.04 | 346.05 | 471.05 | 401 | 439 | 476 | 515 | 554 | 594 | 633 | 670 | 719 | 0.0502 | 1281 | 1.091 | 94.40 | 31.32 | 2 | 0.0330 | 231 | 0.0008 | 49.47 | 7.389 | 0.1879 | 324688.0 | 198000000 | 125000000000 | 81200000000000 | 0.4396 | 0.2100 | 0.0007 | 0.0000 | 0.0015 | 0.0000 | 0.0054 | 0.0002 | 0.0176 | 0.0008 | 0.0856 | 0.0167 | 0.1397 | 0.0345 | 0.1231 | 0.0336 | 0.1667 | 0.0500 | 0.4597 | 0.8643 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0057 | 0.0003 | 0.0329 | 0.0127 | 0.0559 | 0.0246 | 0.0475 | 0.0180 | 0.0714 | 0.0252 | 0.7845 | 0.9193 | 0.0042 | 0.0190 | 0.0042 | 0.0521 | 0.0140 | 0.0474 | 0.0524 | 0.1232 | 0.1054 | 0.1943 | 0.1795 | 0.1848 | 0.1194 | 0.1327 | 0.1522 | 0.1137 | 0.3687 | 0.1327 | 0.0000 | 0.0026 | 0.0017 | 0.0185 | 0.0503 | 0.0888 | 0.0772 | 0.0943 | 0.6665 | 16 | 30 | 58 | 98 | 145 | 207 | 334 | 573 | 1040 | 0.0125 | 72.60 | 6.612 | 0.3697 | 341631.0 | 484000000 | 806000000000 | 1.47E+15 | 0.3657 | 0.3010 | 0.0271 | 0.0034 | 0.1024 | 0.0083 | 0.1982 | 0.0464 | 0.1992 | 0.1091 | 0.1937 | 0.1605 | 0.1274 | 0.2005 | 0.0763 | 0.1440 | 0.0457 | 0.1451 | 0.0301 | 0.1828 | 0.0006 | 0.0011 | 0.0022 | 0.0019 | 0.0049 | 0.0048 | 0.0175 | 0.0174 | 0.0458 | 0.0451 | 0.0736 | 0.0727 | 0.0584 | 0.0567 | 0.0751 | 0.0729 | 0.7219 | 0.7275 | 0.0005 | 0.0012 | 0.0032 | 0.0039 | 0.0065 | 0.0072 | 0.0159 | 0.0166 | 0.0490 | 0.0479 | 0.0772 | 0.0773 | 0.0599 | 0.0636 | 0.0830 | 0.0742 | 0.7047 | 0.7080 | 0.0005 | 0.0031 | 0.0048 | 0.0174 | 0.0468 | 0.0729 | 0.0592 | 0.0760 | 0.7193 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 404 | 381 | | 364 | 11109 | 91.1 | 12.14 | 8.23 | 2.31 | 76 | 80 | 84 | 87 | 91 | 94 | 97 | 101 | 107 | 0.0564 | 627 | 0.370 | 126.83 | 26.31 | 1 | 1.2060 | 439 | 0.0718 | 0.71 | 2.815 | 0.7088 | 8437.9 | 795470 | 76300000 | 7430000000 | 0.3908 | 0.2100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0192 | 0.0055 | 0.0895 | 0.0714 | 0.1789 | 0.1099 | 0.1278 | 0.0604 | 0.1917 | 0.1044 | 0.3930 | 0.6484 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0117 | 0.0055 | 0.0787 | 0.0714 | 0.1254 | 0.1099 | 0.0671 | 0.0604 | 0.1195 | 0.1044 | 0.5977 | 0.6484 | 0.0333 | 0.0000 | 0.0333 | 0.0000 | 0.0667 | 0.0000 | 0.2667 | 0.0000 | 0.1333 | 0.0000 | 0.2000 | 0.0000 | 0.0667 | 0.0000 | 0.0333 | 0.0000 | 0.1667 | 0.0000 | 0.0055 | 0.0055 | 0.0055 | 0.0546 | 0.1421 | 0.1694 | 0.1038 | 0.1639 | 0.3497 | 5 | 6 | 7 | 8 | 8 | 9 | 9 | 10 | 11 | 0.2651 | 0.45 | 1.038 | 0.6298 | 73.1 | 692.301 | 6934.55 | 73026.4 | 0.5150 | 0.1470 | 0.0084 | 0.0000 | 0.0454 | 0.0006 | 0.1209 | 0.0027 | 0.2055 | 0.0101 | 0.2489 | 0.0293 | 0.2133 | 0.0743 | 0.1150 | 0.1788 | 0.0368 | 0.3510 | 0.0059 | 0.3532 | 0.0002 | 0.0000 | 0.0024 | 0.0000 | 0.0090 | 0.0002 | 0.0345 | 0.0025 | 0.0902 | 0.0128 | 0.1613 | 0.0328 | 0.2251 | 0.0673 | 0.2757 | 0.2320 | 0.2014 | 0.6524 | 0.0871 | 0.3913 | 0.1762 | 0.3337 | 0.2103 | 0.1554 | 0.1847 | 0.0633 | 0.1500 | 0.0368 | 0.1089 | 0.0161 | 0.0537 | 0.0035 | 0.0237 | 0.0000 | 0.0054 | 0.0000 | 0.0034 | 0.0150 | 0.0465 | 0.1072 | 0.1765 | 0.2248 | 0.1975 | 0.1520 | 0.0770 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 921 | 862 | | 6477 | 15065 | 403.9 | 109.37 | 121.63 | 165.75 | 277 | 309 | 337 | 363 | 389 | 418 | 449 | 490 | 551 | 0.0525 | 791 | 0.968 | 109.17 | 33.06 | 1 | 0.0426 | 276 | 0.0006 | 77.54 | 7.589 | 0.1419 | 175073.0 | 81300000 | 40400000000 | 21300000000000 | 0.4463 | 0.2101 | 0.0000 | 0.0000 | 0.0023 | 0.0000 | 0.0155 | 0.0004 | 0.0348 | 0.0028 | 0.1035 | 0.0244 | 0.1860 | 0.0559 | 0.1699 | 0.0627 | 0.1719 | 0.0842 | 0.3162 | 0.7696 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0023 | 0.0002 | 0.0093 | 0.0018 | 0.0399 | 0.0117 | 0.0837 | 0.0302 | 0.0747 | 0.0280 | 0.0983 | 0.0411 | 0.6910 | 0.8871 | 0.0029 | 0.0053 | 0.0174 | 0.0106 | 0.0101 | 0.0301 | 0.0702 | 0.0816 | 0.1259 | 0.1667 | 0.1802 | 0.1613 | 0.0948 | 0.1241 | 0.1324 | 0.1436 | 0.3661 | 0.2766 | 0.0003 | 0.0010 | 0.0055 | 0.0331 | 0.0776 | 0.1479 | 0.1117 | 0.1317 | 0.4912 | 7 | 9 | 13 | 25 | 47 | 84 | 137 | 215 | 339 | 0.0659 | 15.12 | 4.966 | 0.5541 | 42265.8 | 22000000 | 14400000000 | 10800000000000 | 0.3883 | 0.2650 | 0.0173 | 0.0015 | 0.0965 | 0.0090 | 0.2033 | 0.0324 | 0.1790 | 0.0799 | 0.1931 | 0.1735 | 0.1468 | 0.2123 | 0.0950 | 0.1508 | 0.0502 | 0.1388 | 0.0188 | 0.2017 | 0.0002 | 0.0002 | 0.0013 | 0.0011 | 0.0020 | 0.0012 | 0.0089 | 0.0089 | 0.0379 | 0.0318 | 0.0609 | 0.0533 | 0.0508 | 0.0440 | 0.0713 | 0.0640 | 0.7668 | 0.7956 | 0.0000 | 0.0003 | 0.0007 | 0.0005 | 0.0044 | 0.0032 | 0.0125 | 0.0119 | 0.0504 | 0.0631 | 0.0900 | 0.0998 | 0.0666 | 0.0700 | 0.0928 | 0.1054 | 0.6826 | 0.6458 | 0.0002 | 0.0002 | 0.0026 | 0.0098 | 0.0427 | 0.0786 | 0.0642 | 0.0823 | 0.7195 |