High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1130 | 460 | 653 | 578 | 83.3 | 9.22 | 65.56 | 101.38 | 71 | 74 | 78 | 80 | 83 | 86 | 89 | 92 | 95 | 0.3910 | 226 | 0.478 | 77.79 | 11.31 | 1 | 0.3155 | 206 | 0.1159 | 0.55 | 2.394 | 0.7678 | 7017.7 | 598559 | 51600000 | 4510000000 | 0.4222 | 0.2132 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0065 | 0.0015 | 0.0455 | 0.0352 | 0.0698 | 0.0674 | 0.0779 | 0.0260 | 0.1347 | 0.0475 | 0.6623 | 0.8224 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0047 | 0.0015 | 0.0376 | 0.0352 | 0.0610 | 0.0674 | 0.0297 | 0.0260 | 0.0563 | 0.0475 | 0.8075 | 0.8224 | 0.1304 | 0.0000 | 0.3478 | 0.0000 | 0.2174 | 0.0000 | 0.1304 | 0.0000 | 0.0870 | 0.0000 | 0.0435 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0151 | 0.0211 | 0.0452 | 0.0994 | 0.0964 | 0.1325 | 0.1687 | 0.4187 | 7 | 10 | 13 | 18 | 24 | 35 | 52 | 90 | 200 | 0.0809 | 31.27 | 3.431 | 0.5091 | 14559.2 | 5410000 | 2520000000 | 1320000000000 | 0.5610 | 0.0846 | 0.2727 | 0.0094 | 0.5000 | 0.0377 | 0.2273 | 0.4151 | 0.0000 | 0.3396 | 0.0000 | 0.1038 | 0.0000 | 0.0849 | 0.0000 | 0.0094 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0046 | 0.0405 | 0.0091 | 0.0173 | 0.0274 | 0.0347 | 0.0365 | 0.2023 | 0.1507 | 0.3410 | 0.3196 | 0.1676 | 0.1553 | 0.1850 | 0.1918 | 0.0116 | 0.1050 | 0.0155 | 0.0177 | 0.0233 | 0.0265 | 0.0698 | 0.0885 | 0.0853 | 0.0619 | 0.2636 | 0.3894 | 0.3488 | 0.3009 | 0.1860 | 0.1150 | 0.0078 | 0.0000 | 0.0000 | 0.0000 | 0.0134 | 0.0201 | 0.0336 | 0.0336 | 0.2282 | 0.3758 | 0.2013 | 0.0940 | 0.0000 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1200 | 960 | 312 | 3292 | 82.5 | 11.29 | 23.21 | 72.43 | 68 | 73 | 76 | 79 | 82 | 86 | 89 | 93 | 97 | 0.1206 | 397 | 1.136 | 33.29 | 11.66 | 2 | 0.2724 | 85 | 0.0754 | 0.90 | 2.811 | 0.6827 | 6932.2 | 592793 | 51500000 | 4550000000 | 0.3990 | 0.2389 | 0.0037 | 0.0000 | 0.0000 | 0.0032 | 0.0112 | 0.0000 | 0.0485 | 0.0096 | 0.0672 | 0.0737 | 0.1194 | 0.0833 | 0.0933 | 0.0481 | 0.1604 | 0.0705 | 0.4963 | 0.7115 | 0.0034 | 0.0000 | 0.0000 | 0.0032 | 0.0069 | 0.0000 | 0.0206 | 0.0096 | 0.0481 | 0.0737 | 0.0997 | 0.0833 | 0.0378 | 0.0481 | 0.0722 | 0.0705 | 0.7113 | 0.7115 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.2609 | 0.0000 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0120 | 0.0180 | 0.0299 | 0.0539 | 0.0898 | 0.2275 | 0.0958 | 0.1078 | 0.3653 | 5 | 6 | 8 | 8 | 9 | 10 | 11 | 12 | 16 | 0.2788 | 2.99 | 1.539 | 0.6666 | 5783.0 | 2740000 | 1470000000 | 851000000000 | 0.3576 | 0.2571 | 0.1333 | 0.2774 | 0.2167 | 0.1473 | 0.3500 | 0.1130 | 0.1833 | 0.1541 | 0.0833 | 0.1336 | 0.0333 | 0.1199 | 0.0000 | 0.0411 | 0.0000 | 0.0103 | 0.0000 | 0.0034 | 0.0217 | 0.1656 | 0.0072 | 0.0879 | 0.0109 | 0.0573 | 0.0217 | 0.0613 | 0.0435 | 0.0327 | 0.0942 | 0.0675 | 0.0471 | 0.0409 | 0.0870 | 0.0695 | 0.6667 | 0.4172 | 0.0000 | 0.0000 | 0.0093 | 0.0000 | 0.0046 | 0.0000 | 0.0139 | 0.0203 | 0.0509 | 0.0711 | 0.1111 | 0.0863 | 0.0556 | 0.0761 | 0.0787 | 0.0863 | 0.6759 | 0.6599 | 0.0042 | 0.0042 | 0.0211 | 0.0253 | 0.0506 | 0.0717 | 0.0717 | 0.0928 | 0.6582 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 693 | 1758 | 9747 | 194.5 | 65.03 | 7.39 | 2.56 | 126 | 140 | 153 | 164 | 173 | 189 | 216 | 254 | 297 | 0.0806 | 786 | 1.223 | 29.83 | 11.66 | 2 | 0.0438 | 77 | 0.0089 | 2.56 | 5.059 | 0.5219 | 42048.1 | 10100000 | 2640000000 | 742000000000 | 0.3576 | 0.2730 | 0.0013 | 0.0000 | 0.0053 | 0.0007 | 0.0093 | 0.0043 | 0.0200 | 0.0100 | 0.0787 | 0.0400 | 0.1267 | 0.0557 | 0.1067 | 0.0550 | 0.1440 | 0.0764 | 0.5080 | 0.7580 | 0.0008 | 0.0000 | 0.0034 | 0.0006 | 0.0050 | 0.0024 | 0.0101 | 0.0078 | 0.0378 | 0.0269 | 0.0512 | 0.0305 | 0.0419 | 0.0335 | 0.0680 | 0.0449 | 0.7819 | 0.8533 | 0.0023 | 0.0037 | 0.0000 | 0.0037 | 0.0000 | 0.0000 | 0.0090 | 0.0186 | 0.0498 | 0.0520 | 0.0611 | 0.0892 | 0.0452 | 0.0520 | 0.0656 | 0.0743 | 0.7670 | 0.7063 | 0.0000 | 0.0000 | 0.0030 | 0.0076 | 0.0318 | 0.0636 | 0.0394 | 0.0561 | 0.7985 | 4 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0172 | 8.20 | 4.461 | 0.3585 | 61.1 | 562.508 | 5723.84 | 64032.1 | 0.4837 | 0.1687 | 0.0143 | 0.0020 | 0.0491 | 0.0072 | 0.1154 | 0.0186 | 0.1968 | 0.0459 | 0.2244 | 0.0938 | 0.2015 | 0.1724 | 0.1356 | 0.2637 | 0.0542 | 0.2652 | 0.0087 | 0.1312 | 0.0012 | 0.0000 | 0.0093 | 0.0006 | 0.0270 | 0.0038 | 0.0627 | 0.0130 | 0.1007 | 0.0342 | 0.1357 | 0.0750 | 0.1749 | 0.1500 | 0.2022 | 0.2720 | 0.2862 | 0.4515 | 0.1173 | 0.1778 | 0.1454 | 0.1541 | 0.1396 | 0.1171 | 0.1150 | 0.1141 | 0.1015 | 0.0801 | 0.0904 | 0.0898 | 0.0869 | 0.0746 | 0.0800 | 0.0728 | 0.1238 | 0.1195 | 0.0077 | 0.0301 | 0.0649 | 0.1143 | 0.1463 | 0.1559 | 0.1546 | 0.1313 | 0.1950 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1212 | 580 | 1103 | 14618 | 561.7 | 138.16 | 35.88 | 63.16 | 370 | 419 | 468 | 517 | 560 | 608 | 658 | 706 | 751 | 0.0501 | 732 | 0.997 | 49.98 | 12.04 | 3 | 0.1024 | 113 | 0.0028 | 12.27 | 6.069 | 0.2960 | 334620.0 | 209000000 | 136000000000 | 91500000000000 | 0.3419 | 0.2943 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.0000 | 0.0170 | 0.0039 | 0.0679 | 0.0309 | 0.1434 | 0.0588 | 0.0830 | 0.0366 | 0.1264 | 0.0723 | 0.5566 | 0.7975 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0049 | 0.0019 | 0.0317 | 0.0272 | 0.0537 | 0.0497 | 0.0305 | 0.0244 | 0.0464 | 0.0384 | 0.8327 | 0.8585 | 0.0035 | 0.0667 | 0.0035 | 0.1000 | 0.0069 | 0.0667 | 0.0277 | 0.0667 | 0.0415 | 0.1667 | 0.1073 | 0.1667 | 0.0415 | 0.1000 | 0.0484 | 0.1333 | 0.7197 | 0.1333 | 0.0000 | 0.0000 | 0.0037 | 0.0147 | 0.0367 | 0.0606 | 0.0495 | 0.0495 | 0.7853 | 5 | 6 | 8 | 9 | 10 | 12 | 16 | 40 | 115 | 0.1429 | 1.10 | 2.444 | 0.5930 | 5276.5 | 1200000 | 317000000 | 92500000000 | 0.4895 | 0.1637 | 0.0684 | 0.0063 | 0.2928 | 0.0125 | 0.3403 | 0.0859 | 0.1521 | 0.2560 | 0.0665 | 0.3196 | 0.0418 | 0.1674 | 0.0209 | 0.0859 | 0.0114 | 0.0358 | 0.0057 | 0.0304 | 0.0003 | 0.0008 | 0.0006 | 0.0013 | 0.0015 | 0.0043 | 0.0150 | 0.0179 | 0.0479 | 0.0415 | 0.0814 | 0.0672 | 0.0568 | 0.0573 | 0.0912 | 0.0851 | 0.7054 | 0.7246 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0043 | 0.0011 | 0.0149 | 0.0164 | 0.0532 | 0.0611 | 0.0987 | 0.1019 | 0.0664 | 0.0710 | 0.1015 | 0.1111 | 0.6610 | 0.6366 | 0.0000 | 0.0003 | 0.0036 | 0.0098 | 0.0577 | 0.0925 | 0.0584 | 0.1013 | 0.6764 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1179 | 272 | 484 | 417 | 15.1 | 6.24 | 5.44 | 2.42 | 10 | 11 | 12 | 12 | 13 | 15 | 16 | 18 | 23 | 0.4964 | 207 | 0.834 | 37.74 | 12.04 | 0 | 0.2397 | 116 | 0.0096 | 14.01 | 4.972 | 0.3037 | 265.5 | 5621.95 | 142364 | 4170000 | 0.3690 | 0.2458 | 0.0041 | 0.0000 | 0.0207 | 0.0000 | 0.0664 | 0.0000 | 0.1660 | 0.0426 | 0.1618 | 0.0727 | 0.1826 | 0.1053 | 0.1826 | 0.1328 | 0.1369 | 0.1529 | 0.0788 | 0.4937 | 0.0000 | 0.0000 | 0.0146 | 0.0000 | 0.0292 | 0.0000 | 0.0437 | 0.0325 | 0.0787 | 0.0433 | 0.1108 | 0.0584 | 0.1224 | 0.0714 | 0.1866 | 0.0952 | 0.4140 | 0.6991 | 0.0392 | 0.0000 | 0.0392 | 0.0476 | 0.0686 | 0.0635 | 0.0490 | 0.0794 | 0.0784 | 0.1429 | 0.1961 | 0.1111 | 0.0980 | 0.1111 | 0.1275 | 0.1111 | 0.3039 | 0.3333 | 0.0051 | 0.0256 | 0.0718 | 0.0821 | 0.1026 | 0.1333 | 0.1385 | 0.1179 | 0.3231 | 3 | 3 | 4 | 5 | 5 | 7 | 7 | 7 | 9 | 0.0300 | 14.00 | 3.917 | 0.2952 | 35.4 | 257.772 | 2032.6 | 17052.4 | 0.3900 | 0.1941 | 0.1136 | 0.0290 | 0.2652 | 0.0773 | 0.2803 | 0.2174 | 0.1667 | 0.2560 | 0.0909 | 0.2029 | 0.0530 | 0.1353 | 0.0303 | 0.0628 | 0.0000 | 0.0145 | 0.0000 | 0.0048 | 0.0032 | 0.0000 | 0.0194 | 0.0079 | 0.0809 | 0.0159 | 0.1748 | 0.0714 | 0.2201 | 0.1720 | 0.2071 | 0.1746 | 0.1909 | 0.2302 | 0.0906 | 0.2169 | 0.0129 | 0.1111 | 0.0734 | 0.0760 | 0.1751 | 0.2047 | 0.3277 | 0.3392 | 0.2260 | 0.2222 | 0.1186 | 0.0877 | 0.0395 | 0.0292 | 0.0395 | 0.0409 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0433 | 0.1300 | 0.2202 | 0.2238 | 0.1805 | 0.1336 | 0.0542 | 0.0072 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 972 | 177 | 395 | 12546 | 117.2 | 19.48 | 22.21 | 93.56 | 93 | 98 | 104 | 109 | 113 | 121 | 128 | 137 | 146 | 0.0524 | 657 | 1.105 | 42.05 | 12.04 | 0 | 0.2380 | 94 | 0.0471 | 0.93 | 3.300 | 0.6696 | 14103.0 | 1740000 | 221000000 | 28700000000 | 0.3949 | 0.2407 | 0.0000 | 0.0000 | 0.0102 | 0.0000 | 0.0136 | 0.0000 | 0.0374 | 0.0127 | 0.0646 | 0.0433 | 0.1224 | 0.0738 | 0.1327 | 0.0585 | 0.1565 | 0.0916 | 0.4626 | 0.7201 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0085 | 0.0000 | 0.0254 | 0.0127 | 0.0366 | 0.0430 | 0.0732 | 0.0734 | 0.0704 | 0.0532 | 0.0789 | 0.0658 | 0.7042 | 0.7519 | 0.0000 | 0.0000 | 0.0164 | 1.0000 | 0.0492 | 0.0000 | 0.0820 | 0.0000 | 0.0984 | 0.0000 | 0.1639 | 0.0000 | 0.1148 | 0.0000 | 0.1967 | 0.0000 | 0.2787 | 0.0000 | 0.0055 | 0.0055 | 0.0000 | 0.0497 | 0.0552 | 0.0718 | 0.0939 | 0.0939 | 0.6243 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 14 | 0.1205 | 3.55 | 1.534 | 0.4274 | 9246.7 | 8900000 | 10500000000 | 13500000000000 | 0.4645 | 0.1926 | 0.0604 | 0.1758 | 0.1758 | 0.0687 | 0.2582 | 0.0929 | 0.3462 | 0.1414 | 0.1099 | 0.1980 | 0.0385 | 0.1737 | 0.0110 | 0.0747 | 0.0000 | 0.0485 | 0.0000 | 0.0263 | 0.0000 | 0.0672 | 0.0020 | 0.0227 | 0.0099 | 0.0180 | 0.0159 | 0.0164 | 0.0556 | 0.0469 | 0.0724 | 0.0618 | 0.0764 | 0.0641 | 0.1022 | 0.0821 | 0.6657 | 0.6208 | 0.0024 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0026 | 0.0182 | 0.0140 | 0.0654 | 0.0727 | 0.0956 | 0.0969 | 0.0690 | 0.0625 | 0.0920 | 0.0982 | 0.6550 | 0.6531 | 0.0000 | 0.0022 | 0.0065 | 0.0196 | 0.0577 | 0.0882 | 0.0719 | 0.0882 | 0.6656 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 742 | 248 | 1325 | 5484 | 955.8 | 428.77 | 8.01 | 2.97 | 481 | 526 | 610 | 705 | 833 | 1020 | 1224 | 1418 | 1627 | 0.0857 | 470 | 0.902 | 36.72 | 12.08 | 1 | 0.0823 | 109 | 0.0016 | 81.60 | 6.699 | 0.1744 | 1100000.0 | 1440000000 | 2060000000000 | 3.12E+15 | 0.3703 | 0.2538 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0110 | 0.0015 | 0.1801 | 0.0682 | 0.2904 | 0.1091 | 0.1360 | 0.0636 | 0.1324 | 0.1197 | 0.2500 | 0.6348 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0360 | 0.0308 | 0.0596 | 0.0473 | 0.0263 | 0.0226 | 0.0526 | 0.0473 | 0.8241 | 0.8520 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0022 | 0.0128 | 0.0511 | 0.0511 | 0.0644 | 0.0831 | 0.0378 | 0.0511 | 0.0578 | 0.0895 | 0.7867 | 0.7093 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0417 | 0.0609 | 0.0330 | 0.0557 | 0.8070 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 12 | 0.0134 | 9.32 | 4.700 | 0.3378 | 73.0 | 745.296 | 8414.3 | 103808 | 0.4557 | 0.1834 | 0.0246 | 0.0007 | 0.0780 | 0.0051 | 0.1560 | 0.0156 | 0.2275 | 0.0356 | 0.2236 | 0.0749 | 0.1629 | 0.1318 | 0.0948 | 0.2083 | 0.0289 | 0.2962 | 0.0039 | 0.2318 | 0.0045 | 0.0000 | 0.0206 | 0.0000 | 0.0448 | 0.0044 | 0.0775 | 0.0143 | 0.1104 | 0.0457 | 0.1205 | 0.0733 | 0.1415 | 0.1199 | 0.1700 | 0.2262 | 0.3102 | 0.5161 | 0.0910 | 0.1312 | 0.0842 | 0.1131 | 0.0910 | 0.1508 | 0.1045 | 0.1146 | 0.1270 | 0.1071 | 0.1222 | 0.1056 | 0.1283 | 0.1071 | 0.1236 | 0.0920 | 0.1283 | 0.0784 | 0.0246 | 0.0667 | 0.0896 | 0.1051 | 0.0958 | 0.1127 | 0.1221 | 0.1629 | 0.2206 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 374 | 827 | 538 | 5755 | 91.8 | 48.44 | 171.54 | 297.95 | 29 | 40 | 57 | 74 | 89 | 101 | 116 | 140 | 161 | 0.0895 | 515 | 1.275 | 31.62 | 12.17 | 2 | 0.1543 | 83 | 0.0025 | 70.15 | 6.080 | 0.1560 | 10772.9 | 1460000 | 216000000 | 34000000000 | 0.3272 | 0.2735 | 0.0000 | 0.0000 | 0.0282 | 0.0000 | 0.1338 | 0.0000 | 0.1901 | 0.0198 | 0.1620 | 0.1581 | 0.1268 | 0.1937 | 0.1479 | 0.1621 | 0.1056 | 0.1581 | 0.1056 | 0.3083 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0031 | 0.0131 | 0.0800 | 0.0551 | 0.0985 | 0.0866 | 0.0431 | 0.0525 | 0.1138 | 0.0840 | 0.6585 | 0.7087 | 0.0000 | 0.0000 | 0.0000 | 0.0156 | 0.0055 | 0.0000 | 0.0383 | 0.0156 | 0.1038 | 0.1328 | 0.1038 | 0.1016 | 0.1093 | 0.1016 | 0.1421 | 0.1328 | 0.4973 | 0.5000 | 0.0000 | 0.0000 | 0.0078 | 0.0389 | 0.0661 | 0.1128 | 0.0973 | 0.1128 | 0.5642 | 17 | 19 | 20 | 22 | 25 | 35 | 92 | 249 | 645 | 0.1812 | 27.53 | 3.742 | 0.6466 | 118185.0 | 112000000 | 119000000000 | 139000000000000 | 0.7250 | 0.0477 | 0.0600 | 0.0080 | 0.2240 | 0.0282 | 0.3600 | 0.1690 | 0.1600 | 0.1932 | 0.0920 | 0.2012 | 0.0480 | 0.1469 | 0.0240 | 0.1066 | 0.0240 | 0.0624 | 0.0080 | 0.0845 | 0.0000 | 0.0000 | 0.0007 | 0.0006 | 0.0020 | 0.0012 | 0.0231 | 0.0168 | 0.0909 | 0.0895 | 0.1324 | 0.1111 | 0.0856 | 0.0847 | 0.1232 | 0.1219 | 0.5422 | 0.5742 | 0.0000 | 0.0000 | 0.0047 | 0.0060 | 0.0087 | 0.0146 | 0.0379 | 0.0368 | 0.0883 | 0.0856 | 0.1270 | 0.1336 | 0.1017 | 0.0967 | 0.1222 | 0.1182 | 0.5095 | 0.5086 | 0.0000 | 0.0000 | 0.0086 | 0.0281 | 0.0944 | 0.1354 | 0.0929 | 0.1218 | 0.5187 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 270 | 229 | 650 | 7025 | 1251.1 | 283.87 | 11.58 | 3.56 | 859 | 957 | 1050 | 1150 | 1249 | 1356 | 1450 | 1553 | 1640 | 0.0757 | 532 | 1.003 | 35.47 | 12.37 | 1 | 0.1554 | 101 | 0.0018 | 76.01 | 6.355 | 0.1286 | 1650000.0 | 2260000000 | 3210000000000 | 4.71E+15 | 0.3546 | 0.2714 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0861 | 0.0357 | 0.1632 | 0.0683 | 0.0950 | 0.0233 | 0.1424 | 0.0714 | 0.5104 | 0.8012 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0405 | 0.0356 | 0.0729 | 0.0681 | 0.0304 | 0.0232 | 0.0547 | 0.0464 | 0.7996 | 0.8266 | 0.0000 | 1.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0127 | 0.0000 | 0.0828 | 0.0000 | 0.1083 | 0.0000 | 0.0573 | 0.0000 | 0.1083 | 0.0000 | 0.6306 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0093 | 0.0556 | 0.0710 | 0.0525 | 0.0556 | 0.7562 | 7 | 9 | 10 | 11 | 11 | 12 | 13 | 14 | 16 | 0.0081 | 16.06 | 5.190 | 0.2777 | 146.9 | 2017.49 | 29808.4 | 471003 | 0.4942 | 0.1529 | 0.0108 | 0.0007 | 0.0396 | 0.0047 | 0.0930 | 0.0132 | 0.1508 | 0.0346 | 0.2124 | 0.0636 | 0.2362 | 0.1307 | 0.1635 | 0.2187 | 0.0792 | 0.3144 | 0.0144 | 0.2194 | 0.0046 | 0.0002 | 0.0197 | 0.0029 | 0.0427 | 0.0088 | 0.0534 | 0.0212 | 0.0813 | 0.0412 | 0.1242 | 0.0726 | 0.1697 | 0.1078 | 0.2247 | 0.2453 | 0.2797 | 0.5001 | 0.1226 | 0.2147 | 0.1534 | 0.1587 | 0.1534 | 0.1635 | 0.1480 | 0.1346 | 0.1180 | 0.1010 | 0.0987 | 0.0737 | 0.0887 | 0.0561 | 0.0717 | 0.0657 | 0.0455 | 0.0321 | 0.0277 | 0.0639 | 0.0858 | 0.1141 | 0.1354 | 0.1515 | 0.1521 | 0.1263 | 0.1433 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1074 | 469 | 856 | 4211 | 285.4 | 67.25 | 6.42 | 2.65 | 204 | 219 | 238 | 258 | 279 | 298 | 314 | 342 | 392 | 0.0912 | 384 | 0.307 | 78.41 | 12.65 | 1 | 0.3540 | 303 | 0.0100 | 2.29 | 4.835 | 0.5114 | 85984.1 | 27300000 | 9080000000 | 3150000000000 | 0.3537 | 0.2878 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0190 | 0.0026 | 0.0634 | 0.0408 | 0.1142 | 0.0829 | 0.0846 | 0.0421 | 0.1078 | 0.0523 | 0.6110 | 0.7793 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0078 | 0.0012 | 0.0310 | 0.0315 | 0.0620 | 0.0619 | 0.0326 | 0.0245 | 0.0419 | 0.0304 | 0.8248 | 0.8505 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0139 | 0.0407 | 0.0139 | 0.0407 | 0.1389 | 0.0872 | 0.1389 | 0.0814 | 0.0694 | 0.0930 | 0.1250 | 0.6453 | 0.5000 | 0.0000 | 0.0000 | 0.0025 | 0.0100 | 0.0549 | 0.0549 | 0.0499 | 0.0998 | 0.7282 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 10 | 0.0710 | 0.33 | 0.864 | 0.2971 | 48.3 | 412.798 | 3958 | 42046.3 | 0.4542 | 0.1770 | 0.0146 | 0.0016 | 0.0652 | 0.0082 | 0.1429 | 0.0216 | 0.2233 | 0.0554 | 0.2280 | 0.0976 | 0.2045 | 0.1628 | 0.0871 | 0.2473 | 0.0323 | 0.2561 | 0.0021 | 0.1494 | 0.0003 | 0.0000 | 0.0085 | 0.0008 | 0.0241 | 0.0043 | 0.0564 | 0.0112 | 0.1146 | 0.0394 | 0.1580 | 0.0765 | 0.1970 | 0.1501 | 0.1932 | 0.2793 | 0.2479 | 0.4384 | 0.0927 | 0.1488 | 0.1418 | 0.1187 | 0.1354 | 0.1116 | 0.1297 | 0.1259 | 0.1088 | 0.1731 | 0.1128 | 0.1173 | 0.1225 | 0.0959 | 0.0798 | 0.0658 | 0.0766 | 0.0429 | 0.0125 | 0.0467 | 0.0780 | 0.1010 | 0.1263 | 0.1364 | 0.1335 | 0.1557 | 0.2100 | |
MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 307 | 653 | 10385 | 21337 | 574.1 | 114.46 | 155.18 | 135.73 | 433 | 473 | 505 | 535 | 564 | 596 | 628 | 670 | 733 | 0.0486 | 1036 | 0.577 | 103.02 | 13.04 | 1 | 0.0206 | 214 | 0.0007 | 50.52 | 7.494 | 0.1652 | 342696.0 | 212000000 | 136000000000 | 90600000000000 | 0.4477 | 0.1993 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0000 | 0.0114 | 0.0003 | 0.0529 | 0.0143 | 0.1183 | 0.0275 | 0.1255 | 0.0275 | 0.1535 | 0.0489 | 0.5362 | 0.8814 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0000 | 0.0053 | 0.0001 | 0.0241 | 0.0099 | 0.0493 | 0.0168 | 0.0533 | 0.0122 | 0.0720 | 0.0203 | 0.7946 | 0.9407 | 0.0023 | 0.0176 | 0.0082 | 0.0265 | 0.0164 | 0.0676 | 0.0614 | 0.1088 | 0.1392 | 0.2118 | 0.1766 | 0.2000 | 0.1094 | 0.1294 | 0.1433 | 0.1235 | 0.3433 | 0.1147 | 0.0008 | 0.0010 | 0.0049 | 0.0246 | 0.0722 | 0.1181 | 0.0958 | 0.1311 | 0.5515 | 25 | 42 | 64 | 88 | 118 | 150 | 191 | 249 | 337 | 0.0077 | 23.32 | 5.939 | 0.3643 | 42503.4 | 16400000 | 8080000000 | 4790000000000 | 0.5282 | 0.1429 | 0.0347 | 0.0014 | 0.1391 | 0.0079 | 0.2389 | 0.0792 | 0.1810 | 0.1231 | 0.1607 | 0.1736 | 0.1170 | 0.1882 | 0.0714 | 0.1466 | 0.0353 | 0.1335 | 0.0219 | 0.1463 | 0.0005 | 0.0002 | 0.0011 | 0.0004 | 0.0042 | 0.0024 | 0.0233 | 0.0140 | 0.0793 | 0.0638 | 0.1263 | 0.0985 | 0.1017 | 0.0802 | 0.1398 | 0.1307 | 0.5240 | 0.6098 | 0.0009 | 0.0039 | 0.0053 | 0.0039 | 0.0117 | 0.0141 | 0.0449 | 0.0589 | 0.1098 | 0.1287 | 0.1665 | 0.1769 | 0.1228 | 0.1268 | 0.1550 | 0.1577 | 0.3832 | 0.3291 | 0.0010 | 0.0024 | 0.0071 | 0.0342 | 0.0973 | 0.1484 | 0.1159 | 0.1555 | 0.4382 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 273 | 873 | 959 | 20054 | 113.6 | 15.41 | 28.35 | 38.32 | 95 | 99 | 103 | 107 | 113 | 117 | 121 | 127 | 135 | 0.0524 | 1050 | 1.034 | 39.40 | 13.04 | 0 | 0.1064 | 102 | 0.0763 | 0.50 | 2.832 | 0.7708 | 13136.1 | 1550000 | 186000000 | 22800000000 | 0.4056 | 0.2400 | 0.0012 | 0.0000 | 0.0036 | 0.0010 | 0.0083 | 0.0031 | 0.0154 | 0.0073 | 0.0473 | 0.0241 | 0.0746 | 0.0640 | 0.0734 | 0.0325 | 0.1006 | 0.0598 | 0.6757 | 0.8080 | 0.0011 | 0.0000 | 0.0032 | 0.0010 | 0.0076 | 0.0031 | 0.0108 | 0.0073 | 0.0314 | 0.0229 | 0.0541 | 0.0615 | 0.0400 | 0.0250 | 0.0639 | 0.0532 | 0.7879 | 0.8259 | 0.0000 | 0.0000 | 0.0127 | 0.1667 | 0.0506 | 0.0000 | 0.1013 | 0.5000 | 0.1266 | 0.3333 | 0.1392 | 0.0000 | 0.1266 | 0.0000 | 0.1266 | 0.0000 | 0.3165 | 0.0000 | 0.0022 | 0.0043 | 0.0152 | 0.0260 | 0.0390 | 0.0758 | 0.0736 | 0.1017 | 0.6623 | 11 | 13 | 15 | 17 | 20 | 22 | 26 | 31 | 40 | 0.3245 | 0.91 | 1.880 | 0.8551 | 2272.4 | 507754 | 174000000 | 71000000000 | 0.5696 | 0.1296 | 0.0433 | 0.0176 | 0.0600 | 0.0218 | 0.0785 | 0.0264 | 0.1039 | 0.0386 | 0.1265 | 0.0642 | 0.1678 | 0.0809 | 0.1887 | 0.1079 | 0.1421 | 0.1846 | 0.0893 | 0.4581 | 0.0240 | 0.0144 | 0.0282 | 0.0178 | 0.0330 | 0.0204 | 0.0353 | 0.0280 | 0.0502 | 0.0467 | 0.0618 | 0.0603 | 0.0746 | 0.0721 | 0.1061 | 0.1150 | 0.5867 | 0.6253 | 0.0284 | 0.0348 | 0.0315 | 0.0221 | 0.0495 | 0.0172 | 0.0486 | 0.0255 | 0.0769 | 0.0594 | 0.0874 | 0.0790 | 0.0867 | 0.0795 | 0.1126 | 0.1286 | 0.4784 | 0.5540 | 0.0222 | 0.0261 | 0.0286 | 0.0380 | 0.0551 | 0.0752 | 0.0968 | 0.1505 | 0.5076 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 680 | 628 | 3358 | 11383 | 103.9 | 36.00 | 189.92 | 222.69 | 55 | 73 | 87 | 96 | 104 | 113 | 121 | 132 | 150 | 0.0693 | 789 | 0.744 | 53.00 | 13.15 | 2 | 0.0408 | 137 | 0.0010 | 53.73 | 7.119 | 0.1747 | 12086.9 | 1530000 | 208000000 | 30200000000 | 0.4241 | 0.1918 | 0.0000 | 0.0000 | 0.0045 | 0.0012 | 0.0166 | 0.0028 | 0.0487 | 0.0107 | 0.1236 | 0.0396 | 0.1818 | 0.0832 | 0.1639 | 0.0788 | 0.1748 | 0.1097 | 0.2862 | 0.6739 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0065 | 0.0034 | 0.0352 | 0.0250 | 0.0660 | 0.0370 | 0.0567 | 0.0301 | 0.0895 | 0.0510 | 0.7456 | 0.8534 | 0.0011 | 0.0025 | 0.0066 | 0.0127 | 0.0287 | 0.0253 | 0.0562 | 0.0911 | 0.1257 | 0.1671 | 0.1312 | 0.1873 | 0.1125 | 0.1013 | 0.1389 | 0.1646 | 0.3991 | 0.2481 | 0.0023 | 0.0006 | 0.0053 | 0.0299 | 0.0679 | 0.1066 | 0.0978 | 0.1101 | 0.5796 | 14 | 17 | 23 | 40 | 82 | 156 | 248 | 368 | 533 | 0.0760 | 19.94 | 5.078 | 0.5051 | 85655.4 | 51000000 | 35300000000 | 27300000000000 | 0.6172 | 0.0984 | 0.0318 | 0.0041 | 0.1500 | 0.0191 | 0.2403 | 0.0909 | 0.1748 | 0.1415 | 0.1639 | 0.1829 | 0.1281 | 0.1921 | 0.0616 | 0.1271 | 0.0318 | 0.1054 | 0.0179 | 0.1369 | 0.0002 | 0.0006 | 0.0011 | 0.0010 | 0.0067 | 0.0019 | 0.0132 | 0.0101 | 0.0529 | 0.0477 | 0.1008 | 0.0924 | 0.0697 | 0.0570 | 0.0934 | 0.0891 | 0.6621 | 0.7003 | 0.0014 | 0.0009 | 0.0047 | 0.0046 | 0.0143 | 0.0118 | 0.0201 | 0.0236 | 0.0593 | 0.0611 | 0.1023 | 0.1045 | 0.0662 | 0.0856 | 0.1017 | 0.1135 | 0.6300 | 0.5945 | 0.0005 | 0.0017 | 0.0083 | 0.0225 | 0.0605 | 0.1037 | 0.0722 | 0.0930 | 0.6376 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 658 | 168 | 403 | 1766 | 68.5 | 19.76 | 7.99 | 2.37 | 49 | 53 | 56 | 59 | 63 | 70 | 74 | 85 | 98 | 0.1750 | 309 | 1.167 | 34.83 | 13.34 | 1 | 0.2258 | 91 | 0.0533 | 1.76 | 3.525 | 0.6505 | 5083.4 | 408505 | 35400000 | 3290000000 | 0.4186 | 0.2106 | 0.0050 | 0.0000 | 0.0347 | 0.0029 | 0.1139 | 0.0233 | 0.1139 | 0.0437 | 0.1386 | 0.0962 | 0.1238 | 0.1895 | 0.1386 | 0.1137 | 0.1238 | 0.1429 | 0.2079 | 0.3878 | 0.0034 | 0.0000 | 0.0103 | 0.0000 | 0.0206 | 0.0052 | 0.0412 | 0.0129 | 0.1237 | 0.0722 | 0.1340 | 0.1727 | 0.0790 | 0.0851 | 0.0962 | 0.1134 | 0.4914 | 0.5387 | 0.0112 | 0.0000 | 0.0112 | 0.0000 | 0.0000 | 0.0667 | 0.1236 | 0.2444 | 0.1685 | 0.2222 | 0.2360 | 0.2667 | 0.0787 | 0.0222 | 0.1461 | 0.0667 | 0.2247 | 0.1111 | 0.0000 | 0.0000 | 0.0117 | 0.0526 | 0.1287 | 0.1988 | 0.0877 | 0.1345 | 0.3860 | 5 | 6 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0170 | 10.27 | 4.413 | 0.3266 | 69.5 | 648.007 | 6410.02 | 66817.3 | 0.4806 | 0.1782 | 0.0225 | 0.0013 | 0.0688 | 0.0040 | 0.1865 | 0.0092 | 0.2678 | 0.0257 | 0.2240 | 0.0870 | 0.1502 | 0.1087 | 0.0601 | 0.1963 | 0.0138 | 0.3057 | 0.0063 | 0.2622 | 0.0049 | 0.0000 | 0.0154 | 0.0018 | 0.0561 | 0.0054 | 0.0829 | 0.0127 | 0.1488 | 0.0647 | 0.1715 | 0.0810 | 0.1837 | 0.0906 | 0.2179 | 0.2502 | 0.1187 | 0.4937 | 0.1230 | 0.3869 | 0.2181 | 0.2993 | 0.2645 | 0.1314 | 0.1763 | 0.1314 | 0.1137 | 0.0292 | 0.0650 | 0.0219 | 0.0232 | 0.0000 | 0.0139 | 0.0000 | 0.0023 | 0.0000 | 0.0089 | 0.0445 | 0.0870 | 0.1235 | 0.1966 | 0.2184 | 0.1601 | 0.1235 | 0.0375 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 653 | 516 | 909 | 892 | 22.8 | 11.51 | 5.20 | 1.87 | 10 | 12 | 15 | 18 | 21 | 23 | 27 | 31 | 38 | 0.3509 | 313 | 1.192 | 32.02 | 13.34 | 0 | 0.0957 | 87 | 0.0035 | 17.77 | 5.844 | 0.2797 | 651.5 | 22448.7 | 894003 | 39700000 | 0.3319 | 0.2816 | 0.0000 | 0.0019 | 0.0202 | 0.0000 | 0.0847 | 0.0133 | 0.0605 | 0.0475 | 0.1613 | 0.0665 | 0.2016 | 0.1141 | 0.1855 | 0.1255 | 0.1935 | 0.1464 | 0.0927 | 0.4848 | 0.0000 | 0.0015 | 0.0019 | 0.0000 | 0.0135 | 0.0073 | 0.0250 | 0.0219 | 0.0442 | 0.0335 | 0.0673 | 0.0510 | 0.0635 | 0.0496 | 0.0865 | 0.0700 | 0.6981 | 0.7653 | 0.0000 | 0.0063 | 0.0000 | 0.0063 | 0.0000 | 0.0313 | 0.0478 | 0.0750 | 0.0772 | 0.0938 | 0.1103 | 0.1313 | 0.0809 | 0.1125 | 0.0846 | 0.0875 | 0.5993 | 0.4563 | 0.0051 | 0.0077 | 0.0077 | 0.0281 | 0.0537 | 0.0793 | 0.0793 | 0.0997 | 0.6394 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0223 | 7.70 | 4.011 | 0.3535 | 30.5 | 195.177 | 1334.83 | 9619.86 | 0.5452 | 0.1074 | 0.0732 | 0.0034 | 0.1616 | 0.0358 | 0.2500 | 0.0903 | 0.2348 | 0.1652 | 0.1372 | 0.2129 | 0.1067 | 0.2215 | 0.0244 | 0.1567 | 0.0091 | 0.0716 | 0.0030 | 0.0426 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0377 | 0.0061 | 0.0934 | 0.0547 | 0.1506 | 0.1106 | 0.2218 | 0.1385 | 0.1869 | 0.1823 | 0.2050 | 0.2272 | 0.0976 | 0.2807 | 0.0334 | 0.1483 | 0.1517 | 0.3347 | 0.2699 | 0.3051 | 0.2416 | 0.1525 | 0.1645 | 0.0551 | 0.0848 | 0.0042 | 0.0437 | 0.0000 | 0.0103 | 0.0000 | 0.0000 | 0.0000 | 0.0071 | 0.0321 | 0.1214 | 0.1821 | 0.2304 | 0.2054 | 0.1232 | 0.0804 | 0.0179 | |
Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 925 | 483 | 3069 | 17112 | 133.0 | 40.22 | 103.86 | 203.05 | 76 | 97 | 114 | 125 | 135 | 144 | 156 | 169 | 185 | 0.0464 | 794 | 0.346 | 113.00 | 13.45 | 1 | 0.1036 | 318 | 0.0020 | 15.03 | 6.464 | 0.2683 | 19308.7 | 2990000 | 486000000 | 82200000000 | 0.3770 | 0.2497 | 0.0000 | 0.0000 | 0.0061 | 0.0008 | 0.0067 | 0.0008 | 0.0223 | 0.0066 | 0.0756 | 0.0370 | 0.1201 | 0.0555 | 0.1066 | 0.0588 | 0.1296 | 0.0867 | 0.5331 | 0.7538 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0004 | 0.0004 | 0.0065 | 0.0033 | 0.0230 | 0.0218 | 0.0390 | 0.0336 | 0.0295 | 0.0251 | 0.0464 | 0.0369 | 0.8553 | 0.8783 | 0.0000 | 0.0072 | 0.0036 | 0.0036 | 0.0109 | 0.0324 | 0.0339 | 0.0755 | 0.0593 | 0.1547 | 0.1186 | 0.1007 | 0.1005 | 0.1583 | 0.1223 | 0.1151 | 0.5508 | 0.3525 | 0.0006 | 0.0006 | 0.0031 | 0.0161 | 0.0433 | 0.0644 | 0.0718 | 0.0934 | 0.7067 | 11 | 13 | 16 | 21 | 29 | 46 | 76 | 134 | 243 | 0.0626 | 20.97 | 4.597 | 0.5710 | 52014.4 | 50700000 | 63400000000 | 88800000000000 | 0.5552 | 0.1464 | 0.0385 | 0.0020 | 0.1709 | 0.0137 | 0.2873 | 0.1186 | 0.1533 | 0.1182 | 0.1415 | 0.1703 | 0.1114 | 0.2121 | 0.0427 | 0.1186 | 0.0369 | 0.1014 | 0.0176 | 0.1452 | 0.0004 | 0.0007 | 0.0010 | 0.0017 | 0.0045 | 0.0040 | 0.0170 | 0.0154 | 0.0622 | 0.0508 | 0.1379 | 0.1125 | 0.0614 | 0.0648 | 0.0821 | 0.0786 | 0.6335 | 0.6716 | 0.0014 | 0.0009 | 0.0049 | 0.0060 | 0.0140 | 0.0158 | 0.0198 | 0.0211 | 0.0673 | 0.0687 | 0.1389 | 0.1378 | 0.0579 | 0.0627 | 0.0826 | 0.0880 | 0.6132 | 0.5990 | 0.0005 | 0.0036 | 0.0082 | 0.0192 | 0.0694 | 0.1387 | 0.0634 | 0.0742 | 0.6229 | |
MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 772 | 323 | 794 | 7091 | 484.4 | 65.35 | 36.00 | 48.85 | 404 | 424 | 442 | 460 | 481 | 495 | 518 | 543 | 578 | 0.0636 | 451 | 0.996 | 53.60 | 13.89 | 2 | 0.1612 | 128 | 0.0034 | 13.68 | 5.871 | 0.2779 | 238955.0 | 120000000 | 61300000000 | 31900000000000 | 0.3670 | 0.2688 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0000 | 0.0000 | 0.0132 | 0.0038 | 0.0471 | 0.0315 | 0.0838 | 0.0693 | 0.0632 | 0.0290 | 0.0897 | 0.0453 | 0.7015 | 0.8212 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0092 | 0.0038 | 0.0330 | 0.0315 | 0.0607 | 0.0693 | 0.0356 | 0.0290 | 0.0567 | 0.0453 | 0.8047 | 0.8212 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0385 | 0.0000 | 0.0513 | 0.0000 | 0.0897 | 0.0000 | 0.1538 | 0.0000 | 0.0769 | 0.0000 | 0.1795 | 0.0000 | 0.4103 | 0.0000 | 0.0000 | 0.0000 | 0.0105 | 0.0210 | 0.0525 | 0.0787 | 0.0709 | 0.0787 | 0.6877 | 8 | 10 | 12 | 15 | 19 | 24 | 32 | 46 | 83 | 0.0654 | 8.26 | 3.794 | 0.6602 | 3682.1 | 710852 | 183000000 | 55400000000 | 0.4200 | 0.2030 | 0.0272 | 0.0084 | 0.0680 | 0.0199 | 0.1088 | 0.0383 | 0.1519 | 0.0577 | 0.1927 | 0.1013 | 0.1621 | 0.1448 | 0.1361 | 0.1401 | 0.0964 | 0.1758 | 0.0567 | 0.3137 | 0.0038 | 0.0044 | 0.0071 | 0.0076 | 0.0134 | 0.0126 | 0.0217 | 0.0199 | 0.0459 | 0.0354 | 0.0584 | 0.0527 | 0.0764 | 0.0594 | 0.0889 | 0.0916 | 0.6845 | 0.7164 | 0.0013 | 0.0032 | 0.0066 | 0.0056 | 0.0119 | 0.0071 | 0.0291 | 0.0333 | 0.0984 | 0.0881 | 0.0905 | 0.1079 | 0.0707 | 0.1000 | 0.1288 | 0.1087 | 0.5627 | 0.5460 | 0.0011 | 0.0069 | 0.0058 | 0.0185 | 0.0627 | 0.0801 | 0.0764 | 0.1091 | 0.6394 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1163 | 489 | 321 | 5383 | 116.6 | 17.58 | 10.59 | 16.86 | 93 | 99 | 105 | 110 | 115 | 122 | 128 | 133 | 140 | 0.0832 | 448 | 1.174 | 34.48 | 13.89 | 3 | 0.2897 | 93 | 0.0412 | 1.34 | 3.375 | 0.6192 | 13896.5 | 1690000 | 210000000 | 26600000000 | 0.3932 | 0.2232 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0000 | 0.0388 | 0.0156 | 0.0930 | 0.0498 | 0.1395 | 0.1090 | 0.1395 | 0.0592 | 0.1938 | 0.0935 | 0.3837 | 0.6729 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0243 | 0.0156 | 0.0590 | 0.0498 | 0.1007 | 0.1090 | 0.0833 | 0.0592 | 0.1111 | 0.0935 | 0.6146 | 0.6729 | 0.0333 | 0.0000 | 0.0667 | 0.0000 | 0.0333 | 0.0000 | 0.1667 | 0.0000 | 0.2667 | 0.0000 | 0.2000 | 0.0000 | 0.1000 | 0.0000 | 0.1000 | 0.0000 | 0.0333 | 0.0000 | 0.0000 | 0.0000 | 0.0258 | 0.0516 | 0.0839 | 0.1290 | 0.0710 | 0.1032 | 0.5355 | 3 | 5 | 6 | 6 | 7 | 8 | 9 | 10 | 13 | 0.1037 | 0.50 | 1.327 | 0.4010 | 396.2 | 39837.1 | 5690000 | 976000000 | 0.5867 | 0.1158 | 0.1081 | 0.0234 | 0.1521 | 0.0646 | 0.1822 | 0.1055 | 0.1683 | 0.1248 | 0.1992 | 0.1564 | 0.1228 | 0.1745 | 0.0533 | 0.1681 | 0.0139 | 0.1293 | 0.0000 | 0.0533 | 0.0717 | 0.0199 | 0.1019 | 0.0545 | 0.1150 | 0.0857 | 0.0980 | 0.0980 | 0.1194 | 0.1193 | 0.1073 | 0.1330 | 0.0772 | 0.1375 | 0.0728 | 0.1248 | 0.2366 | 0.2273 | 0.0433 | 0.0158 | 0.0226 | 0.0204 | 0.0377 | 0.0226 | 0.0377 | 0.0385 | 0.0734 | 0.0973 | 0.1092 | 0.1154 | 0.0923 | 0.0905 | 0.1224 | 0.1222 | 0.4614 | 0.4774 | 0.1188 | 0.1103 | 0.0827 | 0.0562 | 0.0615 | 0.0679 | 0.0679 | 0.0933 | 0.3415 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1053 | 104 | 2330 | 7315 | 404.0 | 189.76 | 84.83 | 144.30 | 168 | 214 | 264 | 314 | 375 | 453 | 527 | 592 | 678 | 0.0932 | 682 | 0.598 | 100.02 | 13.89 | 5 | 0.0927 | 216 | 0.0009 | 43.35 | 7.214 | 0.1661 | 199239.0 | 112000000 | 68300000000 | 44000000000000 | 0.3454 | 0.2664 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0000 | 0.0317 | 0.0172 | 0.1329 | 0.0499 | 0.2341 | 0.0946 | 0.2004 | 0.0851 | 0.1786 | 0.0997 | 0.2143 | 0.6535 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0060 | 0.0052 | 0.0268 | 0.0215 | 0.0357 | 0.0302 | 0.0402 | 0.0279 | 0.0462 | 0.0296 | 0.8444 | 0.8857 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0024 | 0.0000 | 0.0060 | 0.0107 | 0.0441 | 0.0661 | 0.0691 | 0.0946 | 0.0524 | 0.0643 | 0.0799 | 0.1143 | 0.7461 | 0.6482 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0399 | 0.0463 | 0.0399 | 0.0704 | 0.7998 | 21 | 27 | 31 | 34 | 38 | 44 | 54 | 94 | 219 | 0.1318 | 7.03 | 3.250 | 0.7401 | 28015.3 | 26600000 | 42300000000 | 80500000000000 | 0.5119 | 0.1569 | 0.0219 | 0.0200 | 0.0820 | 0.0234 | 0.1530 | 0.0443 | 0.1995 | 0.0747 | 0.2158 | 0.1354 | 0.1503 | 0.1458 | 0.0956 | 0.1519 | 0.0601 | 0.1632 | 0.0219 | 0.2413 | 0.0028 | 0.0096 | 0.0062 | 0.0104 | 0.0068 | 0.0183 | 0.0186 | 0.0246 | 0.0361 | 0.0445 | 0.0559 | 0.0512 | 0.0514 | 0.0608 | 0.0745 | 0.0908 | 0.7477 | 0.6898 | 0.0000 | 0.0000 | 0.0014 | 0.0032 | 0.0057 | 0.0064 | 0.0135 | 0.0216 | 0.0519 | 0.0632 | 0.0811 | 0.0800 | 0.0597 | 0.0752 | 0.0989 | 0.0992 | 0.6878 | 0.6512 | 0.0000 | 0.0000 | 0.0052 | 0.0181 | 0.0413 | 0.0664 | 0.0529 | 0.0896 | 0.7266 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 477 | 785 | 2057 | 7126 | 15.8 | 5.35 | 5.58 | 1.94 | 10 | 11 | 13 | 14 | 15 | 16 | 18 | 20 | 22 | 0.1343 | 957 | 1.077 | 39.62 | 14.00 | 0 | 0.0501 | 103 | 0.0083 | 6.76 | 5.098 | 0.3940 | 278.8 | 5536.95 | 125712 | 3300000 | 0.3803 | 0.2578 | 0.0068 | 0.0000 | 0.0241 | 0.0017 | 0.0395 | 0.0081 | 0.0656 | 0.0237 | 0.1070 | 0.0317 | 0.1466 | 0.0531 | 0.1688 | 0.1073 | 0.2054 | 0.1604 | 0.2363 | 0.6140 | 0.0048 | 0.0000 | 0.0131 | 0.0010 | 0.0220 | 0.0068 | 0.0275 | 0.0167 | 0.0440 | 0.0256 | 0.0557 | 0.0329 | 0.0688 | 0.0605 | 0.0922 | 0.0924 | 0.6717 | 0.7641 | 0.0168 | 0.0437 | 0.0216 | 0.0437 | 0.0481 | 0.0328 | 0.0793 | 0.0656 | 0.0865 | 0.1038 | 0.1346 | 0.1093 | 0.1298 | 0.0710 | 0.1394 | 0.1749 | 0.3438 | 0.3552 | 0.0178 | 0.0231 | 0.0241 | 0.0409 | 0.0409 | 0.0682 | 0.0860 | 0.1091 | 0.5897 | 3 | 4 | 5 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0254 | 8.33 | 4.093 | 0.3635 | 34.9 | 237.89 | 1743 | 13611.8 | 0.5441 | 0.1416 | 0.0029 | 0.0002 | 0.0262 | 0.0017 | 0.0867 | 0.0113 | 0.1633 | 0.0354 | 0.2318 | 0.0789 | 0.2315 | 0.1447 | 0.1584 | 0.2575 | 0.0821 | 0.2968 | 0.0170 | 0.1734 | 0.0004 | 0.0002 | 0.0045 | 0.0006 | 0.0189 | 0.0043 | 0.0680 | 0.0220 | 0.1231 | 0.0509 | 0.2194 | 0.0876 | 0.2719 | 0.1709 | 0.2172 | 0.3403 | 0.0767 | 0.3232 | 0.2384 | 0.4990 | 0.3216 | 0.3638 | 0.2659 | 0.1113 | 0.1235 | 0.0258 | 0.0369 | 0.0000 | 0.0129 | 0.0000 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0115 | 0.0662 | 0.1649 | 0.2477 | 0.2359 | 0.1587 | 0.0825 | 0.0266 | 0.0059 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 815 | 163 | 2938 | 15825 | 562.8 | 165.66 | 10.78 | 7.31 | 288 | 401 | 494 | 571 | 620 | 652 | 677 | 696 | 723 | 0.0577 | 913 | 0.956 | 43.93 | 14.04 | 1 | 0.0388 | 114 | 0.0035 | 13.77 | 6.195 | 0.3459 | 344227.0 | 221000000 | 147000000000 | 100000000000000 | 0.3768 | 0.2427 | 0.0046 | 0.0000 | 0.0069 | 0.0000 | 0.0069 | 0.0004 | 0.0299 | 0.0021 | 0.0851 | 0.0207 | 0.1219 | 0.0435 | 0.0913 | 0.0236 | 0.1296 | 0.0464 | 0.5238 | 0.8632 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0016 | 0.0213 | 0.0175 | 0.0344 | 0.0358 | 0.0222 | 0.0179 | 0.0376 | 0.0350 | 0.8822 | 0.8921 | 0.0022 | 0.0000 | 0.0078 | 0.0100 | 0.0111 | 0.0200 | 0.0388 | 0.0200 | 0.0543 | 0.0800 | 0.1008 | 0.1300 | 0.1008 | 0.0700 | 0.1274 | 0.1400 | 0.5570 | 0.5300 | 0.0006 | 0.0000 | 0.0000 | 0.0050 | 0.0233 | 0.0417 | 0.0267 | 0.0389 | 0.8639 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 19 | 0.2362 | 0.38 | 1.298 | 0.6613 | 169.5 | 3950.18 | 122472 | 4500000 | 0.5976 | 0.1040 | 0.0323 | 0.0020 | 0.0756 | 0.0106 | 0.1133 | 0.0336 | 0.1438 | 0.0726 | 0.1811 | 0.1062 | 0.1857 | 0.1514 | 0.1597 | 0.2027 | 0.0873 | 0.2334 | 0.0211 | 0.1876 | 0.0202 | 0.0012 | 0.0489 | 0.0067 | 0.0693 | 0.0257 | 0.0868 | 0.0568 | 0.1051 | 0.0848 | 0.1135 | 0.1256 | 0.1228 | 0.1539 | 0.1364 | 0.1840 | 0.2969 | 0.3614 | 0.0929 | 0.0470 | 0.0631 | 0.0212 | 0.0423 | 0.0131 | 0.0317 | 0.0217 | 0.0372 | 0.0359 | 0.0533 | 0.0606 | 0.0451 | 0.0526 | 0.0776 | 0.0773 | 0.5568 | 0.6705 | 0.0675 | 0.0951 | 0.0928 | 0.0982 | 0.0980 | 0.0940 | 0.0648 | 0.0545 | 0.3351 | |
MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 332 | 897 | 4130 | 6420 | 525.0 | 190.33 | 45.50 | 77.20 | 256 | 314 | 388 | 474 | 542 | 599 | 659 | 716 | 767 | 0.1092 | 701 | 0.638 | 84.10 | 14.14 | 5 | 0.0482 | 199 | 0.0007 | 53.48 | 7.439 | 0.1929 | 311857.0 | 201000000 | 138000000000 | 98300000000000 | 0.3906 | 0.2301 | 0.0000 | 0.0015 | 0.0031 | 0.0011 | 0.0168 | 0.0011 | 0.0291 | 0.0083 | 0.1034 | 0.0496 | 0.1516 | 0.0931 | 0.1309 | 0.0644 | 0.1072 | 0.0966 | 0.4579 | 0.6842 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0018 | 0.0328 | 0.0255 | 0.0470 | 0.0436 | 0.0303 | 0.0252 | 0.0445 | 0.0370 | 0.8418 | 0.8670 | 0.0000 | 0.0015 | 0.0000 | 0.0046 | 0.0021 | 0.0167 | 0.0104 | 0.0410 | 0.0494 | 0.0819 | 0.0626 | 0.1335 | 0.0494 | 0.1108 | 0.0745 | 0.1457 | 0.7516 | 0.4643 | 0.0000 | 0.0005 | 0.0005 | 0.0045 | 0.0352 | 0.0587 | 0.0352 | 0.0564 | 0.8090 | 8 | 10 | 13 | 15 | 17 | 22 | 31 | 60 | 119 | 0.0622 | 10.67 | 3.904 | 0.6364 | 8028.7 | 3400000 | 2280000000 | 1870000000000 | 0.5362 | 0.1440 | 0.0369 | 0.0169 | 0.0844 | 0.0226 | 0.1082 | 0.0463 | 0.1504 | 0.0993 | 0.1847 | 0.1366 | 0.1821 | 0.1061 | 0.1372 | 0.1163 | 0.0976 | 0.1558 | 0.0185 | 0.3002 | 0.0017 | 0.0057 | 0.0034 | 0.0076 | 0.0040 | 0.0086 | 0.0115 | 0.0195 | 0.0453 | 0.0437 | 0.0539 | 0.0518 | 0.0441 | 0.0456 | 0.0648 | 0.0699 | 0.7713 | 0.7476 | 0.0007 | 0.0025 | 0.0029 | 0.0016 | 0.0102 | 0.0074 | 0.0154 | 0.0164 | 0.0469 | 0.0402 | 0.0608 | 0.0731 | 0.0490 | 0.0484 | 0.0791 | 0.0649 | 0.7350 | 0.7455 | 0.0006 | 0.0051 | 0.0058 | 0.0135 | 0.0398 | 0.0630 | 0.0424 | 0.0694 | 0.7603 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 508 | 386 | 1856 | 6121 | 930.2 | 328.29 | 7.48 | 2.44 | 554 | 653 | 741 | 809 | 938 | 1045 | 1136 | 1227 | 1377 | 0.0853 | 522 | 1.026 | 43.86 | 14.14 | 1 | 0.0641 | 119 | 0.0008 | 115.28 | 7.271 | 0.1207 | 972996.0 | 1100000000 | 1310000000000 | 1.62E+15 | 0.4447 | 0.1728 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0173 | 0.0007 | 0.0317 | 0.0064 | 0.1400 | 0.0443 | 0.2107 | 0.1180 | 0.1486 | 0.0730 | 0.1962 | 0.1001 | 0.2554 | 0.6574 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0006 | 0.0093 | 0.0030 | 0.0388 | 0.0270 | 0.0705 | 0.0642 | 0.0496 | 0.0354 | 0.0659 | 0.0564 | 0.7651 | 0.8134 | 0.0034 | 0.0000 | 0.0000 | 0.0074 | 0.0000 | 0.0037 | 0.0201 | 0.0260 | 0.0586 | 0.1078 | 0.1273 | 0.1933 | 0.0771 | 0.0818 | 0.1039 | 0.0855 | 0.6097 | 0.4944 | 0.0000 | 0.0000 | 0.0000 | 0.0053 | 0.0427 | 0.0907 | 0.0491 | 0.0768 | 0.7353 | 5 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0178 | 7.81 | 4.411 | 0.3613 | 61.9 | 562.793 | 5603.58 | 60707.4 | 0.4721 | 0.1687 | 0.0133 | 0.0031 | 0.0511 | 0.0061 | 0.1011 | 0.0157 | 0.1867 | 0.0367 | 0.2357 | 0.0887 | 0.1933 | 0.1507 | 0.1532 | 0.2219 | 0.0544 | 0.2907 | 0.0113 | 0.1863 | 0.0006 | 0.0000 | 0.0046 | 0.0003 | 0.0191 | 0.0016 | 0.0469 | 0.0087 | 0.0879 | 0.0304 | 0.1387 | 0.0535 | 0.1808 | 0.0957 | 0.2333 | 0.2328 | 0.2882 | 0.5769 | 0.0957 | 0.1536 | 0.1428 | 0.1826 | 0.1400 | 0.1273 | 0.1328 | 0.0834 | 0.1079 | 0.0869 | 0.1063 | 0.0860 | 0.0847 | 0.0808 | 0.0841 | 0.0939 | 0.1057 | 0.1054 | 0.0056 | 0.0360 | 0.0685 | 0.1045 | 0.1391 | 0.1650 | 0.1550 | 0.1468 | 0.1796 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 159 | 548 | 379 | 3429 | 61.1 | 11.87 | 9.11 | 3.08 | 46 | 49 | 53 | 56 | 61 | 64 | 69 | 74 | 78 | 0.1105 | 379 | 1.104 | 39.12 | 14.21 | 3 | 0.2797 | 106 | 0.0614 | 0.78 | 2.978 | 0.7032 | 3871.4 | 253941 | 17200000 | 1190000000 | 0.4114 | 0.2187 | 0.0000 | 0.0000 | 0.0338 | 0.0000 | 0.0211 | 0.0027 | 0.0717 | 0.0133 | 0.1392 | 0.0398 | 0.1477 | 0.0928 | 0.1477 | 0.0398 | 0.1181 | 0.0955 | 0.3207 | 0.7162 | 0.0000 | 0.0000 | 0.0223 | 0.0000 | 0.0096 | 0.0026 | 0.0287 | 0.0132 | 0.0510 | 0.0396 | 0.0701 | 0.0923 | 0.0605 | 0.0343 | 0.0764 | 0.0686 | 0.6815 | 0.7493 | 0.0000 | 0.0000 | 0.0000 | 1.0000 | 0.0519 | 0.0000 | 0.0649 | 0.0000 | 0.2208 | 0.0000 | 0.1818 | 0.0000 | 0.2078 | 0.0000 | 0.1688 | 0.0000 | 0.1039 | 0.0000 | 0.0000 | 0.0209 | 0.0105 | 0.0419 | 0.0995 | 0.0942 | 0.1047 | 0.1152 | 0.5131 | 5 | 7 | 7 | 8 | 9 | 10 | 10 | 11 | 13 | 0.0137 | 13.19 | 4.745 | 0.3048 | 92.4 | 1038.16 | 12866.9 | 175722 | 0.4767 | 0.1774 | 0.0306 | 0.0011 | 0.0977 | 0.0053 | 0.1939 | 0.0174 | 0.2558 | 0.0474 | 0.2165 | 0.0913 | 0.1348 | 0.1588 | 0.0547 | 0.2421 | 0.0160 | 0.2736 | 0.0000 | 0.1629 | 0.0040 | 0.0000 | 0.0215 | 0.0007 | 0.0553 | 0.0059 | 0.0975 | 0.0180 | 0.1615 | 0.0475 | 0.1708 | 0.0992 | 0.1550 | 0.1490 | 0.1519 | 0.2449 | 0.1826 | 0.4348 | 0.1258 | 0.1928 | 0.1479 | 0.1639 | 0.1336 | 0.1470 | 0.1291 | 0.1012 | 0.1049 | 0.1036 | 0.0894 | 0.1108 | 0.0993 | 0.0916 | 0.1038 | 0.0675 | 0.0662 | 0.0217 | 0.0221 | 0.0550 | 0.1024 | 0.1185 | 0.1422 | 0.1212 | 0.1315 | 0.1245 | 0.1827 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 305 | 577 | 1224 | 107.4 | 19.71 | 5.63 | 1.94 | 82 | 89 | 96 | 101 | 108 | 113 | 118 | 125 | 133 | 0.2230 | 273 | 1.197 | 35.36 | 14.21 | 1 | 0.1664 | 96 | 0.0277 | 1.58 | 3.824 | 0.5880 | 11913.2 | 1360000 | 161000000 | 19400000000 | 0.3940 | 0.2372 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0051 | 0.0000 | 0.0304 | 0.0018 | 0.0658 | 0.0406 | 0.1392 | 0.0689 | 0.1342 | 0.0548 | 0.1519 | 0.0707 | 0.4709 | 0.7633 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0000 | 0.0000 | 0.0143 | 0.0017 | 0.0369 | 0.0399 | 0.0656 | 0.0624 | 0.0615 | 0.0295 | 0.0820 | 0.0503 | 0.7377 | 0.8163 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0968 | 0.6364 | 0.1290 | 0.1818 | 0.2796 | 0.0909 | 0.1075 | 0.0909 | 0.1398 | 0.0000 | 0.2473 | 0.0000 | 0.0034 | 0.0068 | 0.0169 | 0.0203 | 0.0811 | 0.0980 | 0.0743 | 0.0845 | 0.6149 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0263 | 7.62 | 3.939 | 0.3680 | 35.5 | 244.168 | 1810.28 | 14316.1 | 0.5714 | 0.1153 | 0.0047 | 0.0000 | 0.0712 | 0.0040 | 0.1377 | 0.0160 | 0.2389 | 0.0419 | 0.2358 | 0.1028 | 0.2294 | 0.1766 | 0.0585 | 0.2535 | 0.0190 | 0.2685 | 0.0047 | 0.1367 | 0.0000 | 0.0000 | 0.0154 | 0.0019 | 0.0475 | 0.0065 | 0.1342 | 0.0260 | 0.1853 | 0.0854 | 0.2601 | 0.1365 | 0.1936 | 0.2201 | 0.1211 | 0.2934 | 0.0428 | 0.2303 | 0.3190 | 0.5467 | 0.3667 | 0.3333 | 0.1571 | 0.1067 | 0.1238 | 0.0133 | 0.0286 | 0.0000 | 0.0048 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0280 | 0.1226 | 0.1559 | 0.1961 | 0.2259 | 0.1471 | 0.0753 | 0.0350 | 0.0140 |