High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 739 | 828 | 3336 | 10996 | 733.4 | 131.67 | 162.29 | 302.51 | 560 | 619 | 661 | 696 | 729 | 766 | 805 | 848 | 907 | 0.0851 | 936 | 1.020 | 70.01 | 22.36 | 1 | 0.0525 | 175 | 0.0011 | 45.93 | 7.024 | 0.1864 | 555153.0 | 433000000 | 346000000000 | 284000000000000 | 0.4491 | 0.1924 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0070 | 0.0003 | 0.0488 | 0.0168 | 0.1141 | 0.0324 | 0.0930 | 0.0251 | 0.1439 | 0.0321 | 0.5920 | 0.8934 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0003 | 0.0255 | 0.0157 | 0.0541 | 0.0275 | 0.0375 | 0.0151 | 0.0620 | 0.0236 | 0.8185 | 0.9178 | 0.0041 | 0.0000 | 0.0000 | 0.0541 | 0.0269 | 0.1081 | 0.0579 | 0.2432 | 0.1467 | 0.1892 | 0.2004 | 0.2973 | 0.1240 | 0.0270 | 0.1508 | 0.0541 | 0.2893 | 0.0270 | 0.0000 | 0.0025 | 0.0105 | 0.0215 | 0.0732 | 0.0942 | 0.0905 | 0.1046 | 0.6031 | 8 | 10 | 11 | 12 | 14 | 20 | 71 | 262 | 593 | 0.2612 | 53.14 | 3.819 | 0.6522 | 117840.0 | 116000000 | 132000000000 | 164000000000000 | 0.5865 | 0.0859 | 0.1144 | 0.0083 | 0.2779 | 0.0904 | 0.2861 | 0.2629 | 0.1417 | 0.1599 | 0.1063 | 0.1460 | 0.0436 | 0.1252 | 0.0272 | 0.0918 | 0.0027 | 0.0668 | 0.0000 | 0.0487 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0007 | 0.0007 | 0.0093 | 0.0101 | 0.0593 | 0.0520 | 0.1052 | 0.1002 | 0.0576 | 0.0598 | 0.1014 | 0.0881 | 0.6657 | 0.6888 | 0.0000 | 0.0008 | 0.0008 | 0.0013 | 0.0024 | 0.0051 | 0.0154 | 0.0166 | 0.0675 | 0.0696 | 0.1110 | 0.1099 | 0.0667 | 0.0743 | 0.1082 | 0.1002 | 0.6280 | 0.6222 | 0.0000 | 0.0007 | 0.0011 | 0.0136 | 0.0618 | 0.1045 | 0.0674 | 0.0986 | 0.6522 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 208 | 697 | 4527 | 6306 | 102.3 | 37.27 | 112.28 | 143.75 | 55 | 71 | 81 | 90 | 99 | 108 | 118 | 131 | 151 | 0.0815 | 514 | 0.356 | 141.55 | 33.02 | 1 | 0.1199 | 543 | 0.0021 | 18.08 | 6.438 | 0.2850 | 11862.3 | 1530000 | 217000000 | 33600000000 | 0.4631 | 0.1918 | 0.0025 | 0.0009 | 0.0066 | 0.0006 | 0.0244 | 0.0036 | 0.0533 | 0.0097 | 0.1102 | 0.0425 | 0.1554 | 0.0857 | 0.1640 | 0.0808 | 0.1971 | 0.1227 | 0.2864 | 0.6534 | 0.0000 | 0.0005 | 0.0003 | 0.0003 | 0.0054 | 0.0021 | 0.0123 | 0.0049 | 0.0377 | 0.0210 | 0.0595 | 0.0395 | 0.0687 | 0.0333 | 0.1013 | 0.0546 | 0.7149 | 0.8438 | 0.0025 | 0.0115 | 0.0025 | 0.0263 | 0.0193 | 0.0197 | 0.0495 | 0.0609 | 0.1050 | 0.1184 | 0.1310 | 0.1760 | 0.1125 | 0.1250 | 0.1453 | 0.1612 | 0.4324 | 0.3010 | 0.0009 | 0.0033 | 0.0127 | 0.0216 | 0.0701 | 0.1040 | 0.0861 | 0.1092 | 0.5920 | 15 | 19 | 25 | 33 | 49 | 75 | 115 | 180 | 306 | 0.0287 | 20.58 | 5.086 | 0.4862 | 33266.2 | 15000000 | 8150000000 | 4970000000000 | 0.6440 | 0.0881 | 0.0377 | 0.0048 | 0.1319 | 0.0168 | 0.1852 | 0.0743 | 0.1397 | 0.1086 | 0.1570 | 0.1829 | 0.1287 | 0.1589 | 0.0958 | 0.1238 | 0.0628 | 0.1286 | 0.0612 | 0.2013 | 0.0013 | 0.0007 | 0.0027 | 0.0015 | 0.0080 | 0.0067 | 0.0212 | 0.0176 | 0.0734 | 0.0639 | 0.1008 | 0.1002 | 0.0787 | 0.0740 | 0.1084 | 0.1073 | 0.6055 | 0.6279 | 0.0018 | 0.0028 | 0.0025 | 0.0035 | 0.0135 | 0.0063 | 0.0308 | 0.0232 | 0.0776 | 0.0752 | 0.1145 | 0.1308 | 0.0844 | 0.0893 | 0.1041 | 0.1069 | 0.5708 | 0.5619 | 0.0016 | 0.0057 | 0.0109 | 0.0274 | 0.0677 | 0.1117 | 0.0858 | 0.1101 | 0.5791 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 559 | 1919 | 9291 | 297.6 | 53.29 | 250.19 | 260.24 | 215 | 254 | 277 | 295 | 308 | 321 | 332 | 343 | 357 | 0.0677 | 629 | 1.003 | 87.82 | 29.21 | 1 | 0.1178 | 226 | 0.0022 | 14.65 | 6.307 | 0.2647 | 91416.6 | 28800000 | 9250000000 | 3020000000000 | 0.3763 | 0.2593 | 0.0007 | 0.0005 | 0.0007 | 0.0000 | 0.0021 | 0.0005 | 0.0084 | 0.0011 | 0.0439 | 0.0183 | 0.0927 | 0.0458 | 0.0836 | 0.0188 | 0.1157 | 0.0285 | 0.6523 | 0.8864 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0012 | 0.0011 | 0.0265 | 0.0183 | 0.0468 | 0.0458 | 0.0302 | 0.0188 | 0.0406 | 0.0285 | 0.8548 | 0.8864 | 0.0105 | 0.0000 | 0.0000 | 0.0000 | 0.1000 | 0.0000 | 0.1263 | 0.0000 | 0.1842 | 0.0000 | 0.1842 | 0.0000 | 0.1421 | 0.0000 | 0.1421 | 0.0000 | 0.1105 | 0.0000 | 0.0000 | 0.0009 | 0.0036 | 0.0217 | 0.0407 | 0.0724 | 0.0733 | 0.1005 | 0.6869 | 21 | 33 | 58 | 95 | 149 | 231 | 329 | 452 | 626 | 0.0131 | 45.83 | 6.311 | 0.3810 | 130308.0 | 91600000 | 76700000000 | 72600000000000 | 0.6100 | 0.0919 | 0.0351 | 0.0025 | 0.1174 | 0.0114 | 0.2999 | 0.0602 | 0.1555 | 0.1210 | 0.1525 | 0.1916 | 0.1254 | 0.2020 | 0.0582 | 0.1432 | 0.0381 | 0.1249 | 0.0181 | 0.1432 | 0.0000 | 0.0000 | 0.0007 | 0.0006 | 0.0030 | 0.0017 | 0.0128 | 0.0101 | 0.0650 | 0.0509 | 0.0904 | 0.0798 | 0.0623 | 0.0612 | 0.1067 | 0.0878 | 0.6591 | 0.7078 | 0.0000 | 0.0004 | 0.0020 | 0.0011 | 0.0059 | 0.0061 | 0.0203 | 0.0318 | 0.0764 | 0.0842 | 0.1147 | 0.1248 | 0.0869 | 0.1083 | 0.1275 | 0.1348 | 0.5664 | 0.5084 | 0.0003 | 0.0011 | 0.0046 | 0.0154 | 0.0733 | 0.0984 | 0.0821 | 0.1146 | 0.6102 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 372 | 139 | 4417 | 11190 | 35.9 | 14.42 | 6.81 | 2.68 | 18 | 23 | 27 | 31 | 35 | 38 | 42 | 47 | 55 | 0.1108 | 1240 | 0.972 | 96.52 | 27.73 | 0 | 0.0541 | 239 | 0.0016 | 19.80 | 6.657 | 0.2399 | 1496.0 | 70708.7 | 3720000 | 215000000 | 0.3566 | 0.2612 | 0.0074 | 0.0033 | 0.0138 | 0.0046 | 0.0275 | 0.0100 | 0.0401 | 0.0219 | 0.0682 | 0.0306 | 0.1181 | 0.0604 | 0.1456 | 0.0764 | 0.2189 | 0.1249 | 0.3605 | 0.6679 | 0.0027 | 0.0016 | 0.0044 | 0.0025 | 0.0061 | 0.0041 | 0.0123 | 0.0106 | 0.0194 | 0.0144 | 0.0310 | 0.0289 | 0.0358 | 0.0324 | 0.0607 | 0.0501 | 0.8275 | 0.8554 | 0.0135 | 0.0136 | 0.0143 | 0.0303 | 0.0236 | 0.0394 | 0.0412 | 0.0455 | 0.0648 | 0.0636 | 0.0732 | 0.0924 | 0.0875 | 0.1030 | 0.1052 | 0.1288 | 0.5766 | 0.4833 | 0.0024 | 0.0118 | 0.0142 | 0.0217 | 0.0307 | 0.0558 | 0.0728 | 0.1281 | 0.6626 | 3 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0130 | 14.88 | 4.690 | 0.2835 | 53.5 | 466.389 | 4418.91 | 44994.1 | 0.5386 | 0.1220 | 0.0193 | 0.0018 | 0.0771 | 0.0147 | 0.1782 | 0.0531 | 0.2352 | 0.1151 | 0.2415 | 0.1932 | 0.1553 | 0.2539 | 0.0676 | 0.2164 | 0.0219 | 0.1202 | 0.0039 | 0.0316 | 0.0009 | 0.0001 | 0.0099 | 0.0021 | 0.0376 | 0.0123 | 0.0944 | 0.0380 | 0.1707 | 0.0873 | 0.2304 | 0.1689 | 0.2167 | 0.2533 | 0.1681 | 0.2793 | 0.0711 | 0.1586 | 0.1499 | 0.2801 | 0.2687 | 0.3198 | 0.2320 | 0.2121 | 0.1617 | 0.1088 | 0.0909 | 0.0480 | 0.0568 | 0.0201 | 0.0279 | 0.0084 | 0.0099 | 0.0022 | 0.0022 | 0.0006 | 0.0072 | 0.0437 | 0.1150 | 0.1799 | 0.2208 | 0.1990 | 0.1331 | 0.0731 | 0.0283 | |
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1002 | 903 | 2590 | 6854 | 671.8 | 130.82 | 57.85 | 118.91 | 504 | 556 | 597 | 632 | 666 | 700 | 730 | 773 | 852 | 0.0926 | 635 | 0.749 | 181.18 | 45.31 | 2 | 0.1853 | 480 | 0.0008 | 66.05 | 7.317 | 0.1448 | 468423.0 | 339000000 | 253000000000 | 195000000000000 | 0.4212 | 0.2260 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0004 | 0.0062 | 0.0020 | 0.0506 | 0.0208 | 0.1069 | 0.0425 | 0.0771 | 0.0261 | 0.1187 | 0.0357 | 0.6398 | 0.8725 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0032 | 0.0008 | 0.0272 | 0.0159 | 0.0614 | 0.0348 | 0.0378 | 0.0147 | 0.0591 | 0.0224 | 0.8113 | 0.9111 | 0.0051 | 0.0000 | 0.0000 | 0.0000 | 0.0103 | 0.0220 | 0.0282 | 0.0879 | 0.0872 | 0.1209 | 0.1385 | 0.1758 | 0.0923 | 0.1868 | 0.1256 | 0.1538 | 0.5128 | 0.2527 | 0.0008 | 0.0000 | 0.0040 | 0.0217 | 0.0593 | 0.1051 | 0.0842 | 0.1043 | 0.6207 | 10 | 12 | 13 | 16 | 22 | 33 | 42 | 64 | 129 | 0.1077 | 12.25 | 3.455 | 0.7303 | 17483.7 | 14800000 | 20400000000 | 35900000000000 | 0.6243 | 0.0943 | 0.0239 | 0.0079 | 0.0613 | 0.0126 | 0.0733 | 0.0238 | 0.1346 | 0.0516 | 0.1891 | 0.0827 | 0.1704 | 0.1263 | 0.1891 | 0.1468 | 0.1193 | 0.1640 | 0.0392 | 0.3843 | 0.0054 | 0.0046 | 0.0113 | 0.0057 | 0.0097 | 0.0092 | 0.0199 | 0.0218 | 0.0485 | 0.0402 | 0.0889 | 0.0766 | 0.0711 | 0.0808 | 0.0867 | 0.0938 | 0.6584 | 0.6673 | 0.0039 | 0.0018 | 0.0024 | 0.0027 | 0.0087 | 0.0064 | 0.0221 | 0.0282 | 0.0559 | 0.0645 | 0.1087 | 0.1064 | 0.0693 | 0.0709 | 0.0969 | 0.0982 | 0.6320 | 0.6209 | 0.0026 | 0.0066 | 0.0066 | 0.0178 | 0.0540 | 0.0949 | 0.0639 | 0.0988 | 0.6548 | |
MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1246 | 203 | 5974 | 10831 | 309.6 | 60.88 | 229.94 | 346.15 | 229 | 256 | 278 | 295 | 310 | 324 | 340 | 361 | 389 | 0.0792 | 858 | 0.570 | 89.36 | 14.42 | 1 | 0.0336 | 201 | 0.0010 | 42.49 | 7.110 | 0.1903 | 99557.1 | 33100000 | 11400000000 | 4030000000000 | 0.4350 | 0.2143 | 0.0005 | 0.0000 | 0.0005 | 0.0003 | 0.0049 | 0.0003 | 0.0155 | 0.0019 | 0.0608 | 0.0167 | 0.1043 | 0.0263 | 0.1316 | 0.0288 | 0.1592 | 0.0436 | 0.5228 | 0.8820 | 0.0004 | 0.0000 | 0.0002 | 0.0003 | 0.0010 | 0.0003 | 0.0058 | 0.0014 | 0.0243 | 0.0127 | 0.0467 | 0.0199 | 0.0505 | 0.0136 | 0.0664 | 0.0216 | 0.8047 | 0.9302 | 0.0043 | 0.0274 | 0.0228 | 0.0479 | 0.0390 | 0.0548 | 0.1029 | 0.1644 | 0.1484 | 0.1986 | 0.1582 | 0.1712 | 0.1387 | 0.1164 | 0.1278 | 0.1370 | 0.2579 | 0.0822 | 0.0007 | 0.0027 | 0.0050 | 0.0219 | 0.0757 | 0.1286 | 0.1173 | 0.1591 | 0.4890 | 4 | 7 | 9 | 12 | 19 | 103 | 267 | 475 | 758 | 0.0830 | 58.23 | 4.859 | 0.4659 | 172683.0 | 171000000 | 200000000000 | 267000000000000 | 0.3514 | 0.2613 | 0.0254 | 0.0000 | 0.1404 | 0.0131 | 0.2860 | 0.0672 | 0.2014 | 0.1345 | 0.1726 | 0.1921 | 0.0660 | 0.2192 | 0.0609 | 0.1432 | 0.0220 | 0.1188 | 0.0254 | 0.1118 | 0.0000 | 0.0000 | 0.0003 | 0.0010 | 0.0008 | 0.0010 | 0.0074 | 0.0049 | 0.0296 | 0.0227 | 0.0565 | 0.0462 | 0.0486 | 0.0366 | 0.0600 | 0.0545 | 0.7969 | 0.8332 | 0.0003 | 0.0000 | 0.0003 | 0.0017 | 0.0022 | 0.0034 | 0.0078 | 0.0112 | 0.0441 | 0.0454 | 0.0789 | 0.0919 | 0.0582 | 0.0671 | 0.0851 | 0.0824 | 0.7230 | 0.6969 | 0.0006 | 0.0009 | 0.0017 | 0.0086 | 0.0356 | 0.0710 | 0.0529 | 0.0690 | 0.7597 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1107 | 725 | 3073 | 3969 | 338.0 | 79.28 | 111.41 | 132.27 | 234 | 267 | 290 | 314 | 335 | 356 | 378 | 405 | 441 | 0.1217 | 483 | 1.226 | 141.20 | 63.63 | 1 | 0.1276 | 392 | 0.0012 | 36.06 | 6.918 | 0.1908 | 120541.0 | 45200000 | 17700000000 | 7230000000000 | 0.4322 | 0.2106 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0044 | 0.0000 | 0.0183 | 0.0046 | 0.0759 | 0.0201 | 0.1506 | 0.0466 | 0.1440 | 0.0508 | 0.1849 | 0.0756 | 0.4219 | 0.8019 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0017 | 0.0000 | 0.0079 | 0.0033 | 0.0277 | 0.0147 | 0.0513 | 0.0287 | 0.0484 | 0.0184 | 0.0778 | 0.0277 | 0.7854 | 0.9068 | 0.0033 | 0.0248 | 0.0082 | 0.0124 | 0.0131 | 0.0559 | 0.0784 | 0.1801 | 0.1373 | 0.2236 | 0.2124 | 0.1677 | 0.1193 | 0.1242 | 0.1373 | 0.1118 | 0.2909 | 0.0994 | 0.0007 | 0.0013 | 0.0060 | 0.0219 | 0.0672 | 0.1203 | 0.1110 | 0.1356 | 0.5359 | 12 | 23 | 35 | 48 | 64 | 85 | 116 | 178 | 274 | 0.0254 | 11.05 | 4.985 | 0.5393 | 29902.0 | 13200000 | 7610000000 | 5130000000000 | 0.5025 | 0.1307 | 0.0142 | 0.0010 | 0.0548 | 0.0120 | 0.1258 | 0.0239 | 0.1400 | 0.0658 | 0.1826 | 0.1396 | 0.1562 | 0.1854 | 0.1014 | 0.1206 | 0.1055 | 0.1356 | 0.1197 | 0.3161 | 0.0006 | 0.0000 | 0.0000 | 0.0026 | 0.0019 | 0.0036 | 0.0130 | 0.0104 | 0.0467 | 0.0410 | 0.0746 | 0.0607 | 0.0655 | 0.0524 | 0.0966 | 0.0841 | 0.7010 | 0.7451 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0038 | 0.0043 | 0.0076 | 0.0152 | 0.0725 | 0.0769 | 0.0925 | 0.1073 | 0.0620 | 0.0921 | 0.1115 | 0.1138 | 0.6501 | 0.5894 | 0.0024 | 0.0016 | 0.0041 | 0.0114 | 0.0571 | 0.0702 | 0.0637 | 0.0980 | 0.6914 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 665 | 315 | 3881 | 7921 | 606.2 | 94.41 | 68.43 | 170.19 | 472 | 541 | 568 | 588 | 606 | 629 | 660 | 694 | 726 | 0.0917 | 726 | 0.976 | 112.07 | 42.38 | 2 | 0.0825 | 320 | 0.0014 | 32.18 | 6.910 | 0.2353 | 376420.0 | 239000000 | 154000000000 | 101000000000000 | 0.4392 | 0.1933 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0052 | 0.0005 | 0.0345 | 0.0169 | 0.0495 | 0.0301 | 0.0505 | 0.0161 | 0.0697 | 0.0270 | 0.7890 | 0.9095 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0005 | 0.0212 | 0.0169 | 0.0256 | 0.0301 | 0.0206 | 0.0161 | 0.0317 | 0.0270 | 0.8986 | 0.9095 | 0.0054 | 0.0000 | 0.0161 | 0.0000 | 0.0215 | 0.0000 | 0.0538 | 0.0000 | 0.1048 | 0.0000 | 0.1532 | 0.0000 | 0.1183 | 0.0000 | 0.1263 | 0.0000 | 0.4005 | 0.0000 | 0.0031 | 0.0031 | 0.0097 | 0.0219 | 0.0429 | 0.0566 | 0.0536 | 0.0929 | 0.7163 | 5 | 6 | 7 | 9 | 10 | 11 | 14 | 30 | 209 | 0.1903 | 6.63 | 2.602 | 0.6219 | 33642.3 | 23500000 | 18600000000 | 16100000000000 | 0.5469 | 0.1234 | 0.0143 | 0.0118 | 0.2071 | 0.0059 | 0.2500 | 0.0710 | 0.2357 | 0.1154 | 0.2571 | 0.2308 | 0.0286 | 0.2337 | 0.0071 | 0.1834 | 0.0000 | 0.1065 | 0.0000 | 0.0414 | 0.0000 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0050 | 0.0119 | 0.0114 | 0.0500 | 0.0456 | 0.0738 | 0.0777 | 0.0484 | 0.0428 | 0.0745 | 0.0720 | 0.7407 | 0.7418 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0009 | 0.0089 | 0.0132 | 0.0526 | 0.0545 | 0.0847 | 0.0771 | 0.0455 | 0.0526 | 0.0794 | 0.0808 | 0.7279 | 0.7209 | 0.0000 | 0.0000 | 0.0017 | 0.0093 | 0.0499 | 0.0854 | 0.0448 | 0.0761 | 0.7327 | |||
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 841 | 100 | 7377 | 24941 | 386.3 | 96.75 | 88.88 | 190.82 | 262 | 298 | 330 | 360 | 385 | 408 | 433 | 466 | 515 | 0.0500 | 1246 | 0.563 | 94.76 | 26.17 | 2 | 0.0409 | 302 | 0.0008 | 47.55 | 7.415 | 0.1751 | 158588.0 | 68800000 | 31400000000 | 15000000000000 | 0.4311 | 0.2177 | 0.0002 | 0.0000 | 0.0031 | 0.0005 | 0.0070 | 0.0012 | 0.0283 | 0.0041 | 0.0813 | 0.0252 | 0.1505 | 0.0529 | 0.1401 | 0.0558 | 0.1607 | 0.0799 | 0.4286 | 0.7805 | 0.0000 | 0.0000 | 0.0011 | 0.0001 | 0.0023 | 0.0003 | 0.0099 | 0.0018 | 0.0340 | 0.0163 | 0.0593 | 0.0332 | 0.0508 | 0.0272 | 0.0661 | 0.0402 | 0.7764 | 0.8808 | 0.0040 | 0.0130 | 0.0066 | 0.0238 | 0.0139 | 0.0563 | 0.0615 | 0.0909 | 0.1315 | 0.1970 | 0.1606 | 0.1710 | 0.1269 | 0.1255 | 0.1401 | 0.1299 | 0.3549 | 0.1926 | 0.0005 | 0.0014 | 0.0043 | 0.0220 | 0.0674 | 0.1016 | 0.1003 | 0.1272 | 0.5753 | 4 | 5 | 7 | 8 | 10 | 12 | 18 | 103 | 322 | 0.1971 | 13.23 | 3.393 | 0.6457 | 44309.3 | 31100000 | 25500000000 | 23000000000000 | 0.4510 | 0.1554 | 0.0309 | 0.0028 | 0.1373 | 0.0130 | 0.2921 | 0.0763 | 0.2205 | 0.1516 | 0.1431 | 0.2140 | 0.0986 | 0.1898 | 0.0271 | 0.1395 | 0.0213 | 0.1116 | 0.0290 | 0.1014 | 0.0000 | 0.0003 | 0.0009 | 0.0005 | 0.0007 | 0.0016 | 0.0037 | 0.0063 | 0.0213 | 0.0191 | 0.0374 | 0.0318 | 0.0250 | 0.0278 | 0.0407 | 0.0377 | 0.8703 | 0.8748 | 0.0000 | 0.0002 | 0.0008 | 0.0004 | 0.0004 | 0.0019 | 0.0063 | 0.0064 | 0.0259 | 0.0282 | 0.0468 | 0.0526 | 0.0377 | 0.0404 | 0.0539 | 0.0614 | 0.8281 | 0.8084 | 0.0000 | 0.0004 | 0.0008 | 0.0042 | 0.0213 | 0.0423 | 0.0293 | 0.0477 | 0.8540 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 766 | 509 | 21316 | 24107 | 152.8 | 47.18 | 163.56 | 211.64 | 92 | 112 | 127 | 140 | 153 | 165 | 177 | 192 | 213 | 0.1036 | 2498 | 0.827 | 32.25 | 8.06 | 7 | 0.0040 | 86 | 0.0005 | 77.74 | 7.966 | 0.1418 | 25560.0 | 4600000 | 879000000 | 178000000000 | 0.4877 | 0.1525 | 0.0009 | 0.0000 | 0.0037 | 0.0002 | 0.0149 | 0.0010 | 0.0428 | 0.0072 | 0.1047 | 0.0330 | 0.1809 | 0.0736 | 0.1588 | 0.0762 | 0.1780 | 0.0986 | 0.3152 | 0.7103 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0020 | 0.0004 | 0.0097 | 0.0036 | 0.0325 | 0.0180 | 0.0642 | 0.0375 | 0.0588 | 0.0332 | 0.0797 | 0.0428 | 0.7519 | 0.8643 | 0.0029 | 0.0050 | 0.0051 | 0.0208 | 0.0156 | 0.0337 | 0.0478 | 0.0972 | 0.1088 | 0.1622 | 0.1603 | 0.2009 | 0.1202 | 0.1275 | 0.1473 | 0.1314 | 0.3919 | 0.2212 | 0.0008 | 0.0017 | 0.0048 | 0.0220 | 0.0553 | 0.0994 | 0.0941 | 0.1118 | 0.6100 | 16 | 20 | 29 | 40 | 58 | 89 | 164 | 305 | 506 | 0.0680 | 12.41 | 4.640 | 0.6115 | 71539.6 | 42800000 | 29400000000 | 22000000000000 | 0.5538 | 0.1336 | 0.0351 | 0.0046 | 0.1280 | 0.0167 | 0.2120 | 0.0578 | 0.1783 | 0.0940 | 0.1652 | 0.1624 | 0.1225 | 0.1970 | 0.0736 | 0.1265 | 0.0427 | 0.1262 | 0.0427 | 0.2147 | 0.0004 | 0.0008 | 0.0014 | 0.0014 | 0.0027 | 0.0031 | 0.0150 | 0.0104 | 0.0386 | 0.0411 | 0.0622 | 0.0561 | 0.0522 | 0.0433 | 0.0703 | 0.0687 | 0.7572 | 0.7752 | 0.0009 | 0.0010 | 0.0030 | 0.0044 | 0.0068 | 0.0054 | 0.0149 | 0.0123 | 0.0452 | 0.0465 | 0.0647 | 0.0707 | 0.0588 | 0.0625 | 0.0807 | 0.0936 | 0.7250 | 0.7037 | 0.0003 | 0.0026 | 0.0046 | 0.0144 | 0.0427 | 0.0684 | 0.0512 | 0.0708 | 0.7451 | |
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 580 | 433 | 1493 | 7000 | 280.3 | 39.92 | 26.94 | 45.70 | 230 | 246 | 259 | 269 | 278 | 289 | 298 | 312 | 333 | 0.0730 | 511 | 0.722 | 72.57 | 16.03 | 1 | 0.1092 | 163 | 0.0044 | 8.62 | 5.687 | 0.3499 | 80150.8 | 23400000 | 6950000000 | 2110000000000 | 0.4223 | 0.2148 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0007 | 0.0385 | 0.0235 | 0.0577 | 0.0450 | 0.0513 | 0.0215 | 0.0810 | 0.0403 | 0.7642 | 0.8690 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0007 | 0.0246 | 0.0221 | 0.0377 | 0.0442 | 0.0261 | 0.0181 | 0.0399 | 0.0328 | 0.8681 | 0.8821 | 0.0226 | 0.2000 | 0.0150 | 0.2000 | 0.0526 | 0.4000 | 0.0677 | 0.2000 | 0.0602 | 0.0000 | 0.1053 | 0.0000 | 0.0902 | 0.0000 | 0.1278 | 0.0000 | 0.4586 | 0.0000 | 0.0014 | 0.0014 | 0.0069 | 0.0220 | 0.0495 | 0.0755 | 0.0975 | 0.1319 | 0.6140 | 7 | 8 | 9 | 10 | 12 | 15 | 20 | 33 | 57 | 0.2933 | 1.67 | 2.358 | 0.8342 | 2814.2 | 777978 | 343000000 | 188000000000 | 0.6091 | 0.1098 | 0.0437 | 0.0353 | 0.0542 | 0.0453 | 0.0822 | 0.0637 | 0.1014 | 0.0599 | 0.1294 | 0.0860 | 0.1451 | 0.1083 | 0.1521 | 0.1045 | 0.1573 | 0.1421 | 0.1346 | 0.3548 | 0.0065 | 0.0172 | 0.0101 | 0.0192 | 0.0081 | 0.0204 | 0.0141 | 0.0188 | 0.0252 | 0.0337 | 0.0348 | 0.0425 | 0.0403 | 0.0357 | 0.0685 | 0.0665 | 0.7924 | 0.7459 | 0.0035 | 0.0050 | 0.0042 | 0.0084 | 0.0099 | 0.0168 | 0.0156 | 0.0218 | 0.0453 | 0.0536 | 0.0545 | 0.0662 | 0.0630 | 0.0679 | 0.1288 | 0.1274 | 0.6752 | 0.6329 | 0.0024 | 0.0047 | 0.0082 | 0.0141 | 0.0294 | 0.0500 | 0.0488 | 0.1106 | 0.7318 | |
SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1218 | 150 | 8328 | 20825 | 278.7 | 60.80 | 290.87 | 439.80 | 204 | 240 | 258 | 272 | 285 | 298 | 311 | 327 | 347 | 0.0520 | 1082 | 0.814 | 131.22 | 25.94 | 2 | 0.0359 | 299 | 0.0015 | 25.68 | 6.861 | 0.2311 | 81369.2 | 24600000 | 7610000000 | 2410000000000 | 0.4056 | 0.2353 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0106 | 0.0006 | 0.0413 | 0.0112 | 0.0811 | 0.0241 | 0.0864 | 0.0135 | 0.1377 | 0.0258 | 0.6381 | 0.9247 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0001 | 0.0143 | 0.0100 | 0.0289 | 0.0185 | 0.0247 | 0.0084 | 0.0466 | 0.0146 | 0.8830 | 0.9483 | 0.0055 | 0.0364 | 0.0234 | 0.0182 | 0.0343 | 0.0455 | 0.0810 | 0.1273 | 0.1262 | 0.1364 | 0.1752 | 0.3091 | 0.1371 | 0.0909 | 0.1269 | 0.0727 | 0.2905 | 0.1636 | 0.0015 | 0.0033 | 0.0074 | 0.0220 | 0.0435 | 0.0863 | 0.0844 | 0.1177 | 0.6340 | 7 | 10 | 13 | 17 | 28 | 115 | 308 | 594 | 1020 | 0.0848 | 69.35 | 5.353 | 0.4886 | 278017.0 | 336000000 | 456000000000 | 669000000000000 | 0.5138 | 0.1645 | 0.0468 | 0.0052 | 0.1680 | 0.0170 | 0.2305 | 0.1168 | 0.1460 | 0.1394 | 0.1433 | 0.1748 | 0.1148 | 0.1667 | 0.0661 | 0.1295 | 0.0487 | 0.1130 | 0.0358 | 0.1375 | 0.0003 | 0.0003 | 0.0000 | 0.0003 | 0.0009 | 0.0009 | 0.0078 | 0.0073 | 0.0402 | 0.0330 | 0.0717 | 0.0659 | 0.0532 | 0.0476 | 0.0763 | 0.0708 | 0.7497 | 0.7740 | 0.0002 | 0.0011 | 0.0003 | 0.0020 | 0.0034 | 0.0050 | 0.0145 | 0.0131 | 0.0489 | 0.0487 | 0.0799 | 0.0830 | 0.0597 | 0.0625 | 0.0824 | 0.0882 | 0.7106 | 0.6963 | 0.0002 | 0.0002 | 0.0019 | 0.0108 | 0.0438 | 0.0821 | 0.0547 | 0.0780 | 0.7283 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1036 | 656 | 6909 | 17984 | 410.6 | 89.98 | 149.03 | 156.51 | 291 | 332 | 361 | 387 | 409 | 432 | 457 | 486 | 536 | 0.0622 | 1118 | 0.898 | 69.57 | 17.20 | 1 | 0.0248 | 171 | 0.0008 | 36.78 | 7.401 | 0.1966 | 176674.0 | 79200000 | 36900000000 | 17700000000000 | 0.4312 | 0.2120 | 0.0007 | 0.0000 | 0.0016 | 0.0002 | 0.0034 | 0.0005 | 0.0108 | 0.0020 | 0.0391 | 0.0147 | 0.0913 | 0.0355 | 0.0855 | 0.0290 | 0.1133 | 0.0461 | 0.6543 | 0.8720 | 0.0004 | 0.0000 | 0.0004 | 0.0001 | 0.0025 | 0.0000 | 0.0034 | 0.0009 | 0.0166 | 0.0112 | 0.0378 | 0.0207 | 0.0314 | 0.0124 | 0.0448 | 0.0203 | 0.8629 | 0.9343 | 0.0032 | 0.0000 | 0.0080 | 0.0000 | 0.0135 | 0.0000 | 0.0358 | 0.0000 | 0.0923 | 0.0000 | 0.1146 | 0.0000 | 0.0819 | 0.0000 | 0.1233 | 0.0000 | 0.5274 | 0.0000 | 0.0006 | 0.0024 | 0.0059 | 0.0221 | 0.0489 | 0.0734 | 0.0681 | 0.0943 | 0.6844 | 11 | 14 | 25 | 52 | 91 | 138 | 202 | 281 | 382 | 0.0546 | 17.50 | 5.311 | 0.5113 | 46702.5 | 19100000 | 9060000000 | 4790000000000 | 0.5773 | 0.1082 | 0.0176 | 0.0024 | 0.0828 | 0.0099 | 0.1823 | 0.0387 | 0.1855 | 0.0739 | 0.1780 | 0.1442 | 0.1507 | 0.1991 | 0.0866 | 0.1416 | 0.0663 | 0.1505 | 0.0502 | 0.2396 | 0.0004 | 0.0002 | 0.0013 | 0.0009 | 0.0018 | 0.0020 | 0.0098 | 0.0055 | 0.0367 | 0.0299 | 0.0651 | 0.0490 | 0.0517 | 0.0398 | 0.0765 | 0.0650 | 0.7568 | 0.8077 | 0.0005 | 0.0006 | 0.0005 | 0.0012 | 0.0035 | 0.0038 | 0.0112 | 0.0175 | 0.0539 | 0.0691 | 0.1009 | 0.1110 | 0.0752 | 0.0900 | 0.1122 | 0.1267 | 0.6422 | 0.5802 | 0.0003 | 0.0004 | 0.0029 | 0.0108 | 0.0469 | 0.0779 | 0.0647 | 0.0975 | 0.6985 | |
MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 198 | 613 | 10703 | 25098 | 480.9 | 117.51 | 176.04 | 229.83 | 340 | 382 | 416 | 442 | 466 | 492 | 523 | 565 | 635 | 0.0451 | 1133 | 1.039 | 108.30 | 27.31 | 1 | 0.0238 | 255 | 0.0012 | 25.67 | 7.037 | 0.2548 | 245102.0 | 133000000 | 76300000000 | 46700000000000 | 0.4289 | 0.2132 | 0.0002 | 0.0001 | 0.0017 | 0.0003 | 0.0032 | 0.0004 | 0.0125 | 0.0023 | 0.0362 | 0.0148 | 0.0705 | 0.0249 | 0.0739 | 0.0234 | 0.1025 | 0.0348 | 0.6994 | 0.8989 | 0.0001 | 0.0000 | 0.0011 | 0.0000 | 0.0013 | 0.0000 | 0.0040 | 0.0009 | 0.0147 | 0.0099 | 0.0296 | 0.0144 | 0.0296 | 0.0114 | 0.0431 | 0.0165 | 0.8765 | 0.9467 | 0.0027 | 0.0042 | 0.0037 | 0.0125 | 0.0197 | 0.0111 | 0.0256 | 0.0376 | 0.0809 | 0.0794 | 0.0969 | 0.1059 | 0.0793 | 0.0975 | 0.1145 | 0.1170 | 0.5767 | 0.5348 | 0.0011 | 0.0046 | 0.0057 | 0.0221 | 0.0472 | 0.0715 | 0.0723 | 0.0974 | 0.6780 | 8 | 11 | 18 | 43 | 88 | 143 | 209 | 306 | 470 | 0.0340 | 59.76 | 6.000 | 0.4097 | 83807.8 | 61300000 | 58300000000 | 65200000000000 | 0.4708 | 0.1676 | 0.0402 | 0.0013 | 0.1379 | 0.0145 | 0.2575 | 0.0830 | 0.1639 | 0.1217 | 0.1467 | 0.1865 | 0.1105 | 0.1891 | 0.0710 | 0.1300 | 0.0457 | 0.1206 | 0.0267 | 0.1533 | 0.0004 | 0.0001 | 0.0006 | 0.0003 | 0.0013 | 0.0011 | 0.0127 | 0.0082 | 0.0586 | 0.0466 | 0.0992 | 0.0851 | 0.0724 | 0.0582 | 0.1097 | 0.0882 | 0.6453 | 0.7122 | 0.0004 | 0.0016 | 0.0013 | 0.0016 | 0.0047 | 0.0061 | 0.0204 | 0.0261 | 0.0847 | 0.0889 | 0.1296 | 0.1451 | 0.0831 | 0.0884 | 0.1286 | 0.1255 | 0.5472 | 0.5169 | 0.0007 | 0.0010 | 0.0037 | 0.0134 | 0.0728 | 0.1205 | 0.0761 | 0.1192 | 0.5926 | |||
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 226 | 604 | 4693 | 21436 | 383.8 | 76.01 | 185.02 | 221.64 | 284 | 313 | 337 | 360 | 381 | 402 | 425 | 454 | 486 | 0.0416 | 891 | 1.052 | 130.17 | 34.01 | 1 | 0.0641 | 301 | 0.0008 | 47.52 | 7.327 | 0.1592 | 153105.0 | 63300000 | 27000000000 | 11900000000000 | 0.3995 | 0.2470 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0023 | 0.0002 | 0.0165 | 0.0017 | 0.0621 | 0.0177 | 0.1229 | 0.0293 | 0.1371 | 0.0275 | 0.1688 | 0.0446 | 0.4889 | 0.8790 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0073 | 0.0015 | 0.0275 | 0.0148 | 0.0536 | 0.0238 | 0.0573 | 0.0171 | 0.0744 | 0.0278 | 0.7785 | 0.9150 | 0.0000 | 0.0000 | 0.0120 | 0.0000 | 0.0156 | 0.0000 | 0.0648 | 0.0000 | 0.1212 | 0.0000 | 0.1633 | 0.0000 | 0.1357 | 0.0000 | 0.1465 | 0.0000 | 0.3409 | 0.0000 | 0.0000 | 0.0009 | 0.0069 | 0.0221 | 0.0711 | 0.1111 | 0.0954 | 0.1176 | 0.5748 | 15 | 18 | 24 | 44 | 80 | 141 | 230 | 343 | 529 | 0.0288 | 19.62 | 5.529 | 0.4998 | 83352.2 | 50500000 | 35500000000 | 27500000000000 | 0.4199 | 0.2507 | 0.0207 | 0.0005 | 0.0995 | 0.0062 | 0.2392 | 0.0328 | 0.2041 | 0.0859 | 0.1593 | 0.1798 | 0.1282 | 0.2251 | 0.0610 | 0.1479 | 0.0518 | 0.1262 | 0.0362 | 0.1956 | 0.0004 | 0.0000 | 0.0006 | 0.0003 | 0.0016 | 0.0010 | 0.0080 | 0.0073 | 0.0421 | 0.0351 | 0.0732 | 0.0620 | 0.0459 | 0.0433 | 0.0727 | 0.0653 | 0.7556 | 0.7856 | 0.0000 | 0.0003 | 0.0009 | 0.0012 | 0.0020 | 0.0024 | 0.0131 | 0.0137 | 0.0524 | 0.0608 | 0.0851 | 0.0996 | 0.0622 | 0.0649 | 0.0907 | 0.0941 | 0.6935 | 0.6629 | 0.0001 | 0.0005 | 0.0023 | 0.0104 | 0.0496 | 0.0769 | 0.0547 | 0.0770 | 0.7284 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 688 | 324 | 13758 | 21485 | 122.6 | 40.36 | 202.58 | 231.30 | 76 | 90 | 98 | 107 | 117 | 128 | 141 | 156 | 178 | 0.0872 | 1874 | 0.692 | 86.83 | 17.09 | 4 | 0.0151 | 208 | 0.0009 | 37.58 | 7.369 | 0.2047 | 16661.6 | 2480000 | 400000000 | 69100000000 | 0.4692 | 0.2051 | 0.0024 | 0.0004 | 0.0062 | 0.0006 | 0.0139 | 0.0027 | 0.0405 | 0.0084 | 0.0991 | 0.0326 | 0.1598 | 0.0715 | 0.1633 | 0.0626 | 0.1771 | 0.0877 | 0.3378 | 0.7336 | 0.0011 | 0.0002 | 0.0029 | 0.0003 | 0.0047 | 0.0010 | 0.0145 | 0.0048 | 0.0370 | 0.0172 | 0.0555 | 0.0390 | 0.0585 | 0.0291 | 0.0729 | 0.0411 | 0.7528 | 0.8673 | 0.0020 | 0.0037 | 0.0072 | 0.0067 | 0.0133 | 0.0209 | 0.0372 | 0.0491 | 0.0847 | 0.1098 | 0.1175 | 0.1589 | 0.0893 | 0.1141 | 0.1233 | 0.1387 | 0.5255 | 0.3982 | 0.0010 | 0.0026 | 0.0073 | 0.0221 | 0.0578 | 0.0893 | 0.0766 | 0.1021 | 0.6413 | 15 | 20 | 31 | 57 | 109 | 182 | 259 | 358 | 545 | 0.0237 | 41.98 | 5.971 | 0.4277 | 94535.6 | 60700000 | 46900000000 | 41300000000000 | 0.5071 | 0.1526 | 0.0324 | 0.0022 | 0.1222 | 0.0156 | 0.1953 | 0.0725 | 0.1804 | 0.1085 | 0.1681 | 0.1619 | 0.1340 | 0.1825 | 0.0858 | 0.1314 | 0.0495 | 0.1367 | 0.0324 | 0.1888 | 0.0001 | 0.0005 | 0.0017 | 0.0015 | 0.0035 | 0.0027 | 0.0122 | 0.0106 | 0.0577 | 0.0494 | 0.0901 | 0.0778 | 0.0671 | 0.0552 | 0.0932 | 0.0791 | 0.6743 | 0.7233 | 0.0003 | 0.0010 | 0.0028 | 0.0034 | 0.0068 | 0.0100 | 0.0237 | 0.0359 | 0.0811 | 0.0934 | 0.1246 | 0.1344 | 0.0910 | 0.0879 | 0.1214 | 0.1091 | 0.5482 | 0.5250 | 0.0005 | 0.0019 | 0.0048 | 0.0175 | 0.0673 | 0.1061 | 0.0788 | 0.1115 | 0.6117 | |
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 442 | 641 | 7990 | 25118 | 501.3 | 88.04 | 166.84 | 265.28 | 388 | 427 | 453 | 476 | 498 | 523 | 548 | 577 | 617 | 0.0471 | 1183 | 1.180 | 95.02 | 43.97 | 2 | 0.0333 | 266 | 0.0018 | 18.67 | 6.558 | 0.2470 | 259095.0 | 138000000 | 75200000000 | 42100000000000 | 0.4349 | 0.2174 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0022 | 0.0004 | 0.0081 | 0.0004 | 0.0446 | 0.0106 | 0.0956 | 0.0227 | 0.1034 | 0.0182 | 0.1448 | 0.0317 | 0.6006 | 0.9161 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0003 | 0.0024 | 0.0004 | 0.0209 | 0.0097 | 0.0427 | 0.0195 | 0.0421 | 0.0112 | 0.0628 | 0.0166 | 0.8279 | 0.9424 | 0.0064 | 0.0682 | 0.0091 | 0.0455 | 0.0320 | 0.0795 | 0.0970 | 0.1591 | 0.1473 | 0.2045 | 0.1802 | 0.1591 | 0.1180 | 0.0795 | 0.1455 | 0.0909 | 0.2644 | 0.1136 | 0.0005 | 0.0038 | 0.0054 | 0.0222 | 0.0749 | 0.1073 | 0.1055 | 0.1318 | 0.5485 | 10 | 11 | 14 | 16 | 23 | 59 | 162 | 310 | 534 | 0.1363 | 42.26 | 4.688 | 0.5832 | 98205.2 | 84400000 | 91600000000 | 119000000000000 | 0.4503 | 0.1832 | 0.0986 | 0.0041 | 0.2120 | 0.0293 | 0.2896 | 0.1678 | 0.1638 | 0.1659 | 0.1033 | 0.2136 | 0.0800 | 0.1794 | 0.0287 | 0.0875 | 0.0194 | 0.0736 | 0.0047 | 0.0788 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0006 | 0.0008 | 0.0081 | 0.0047 | 0.0452 | 0.0417 | 0.0840 | 0.0727 | 0.0594 | 0.0422 | 0.0840 | 0.0743 | 0.7185 | 0.7635 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0024 | 0.0121 | 0.0159 | 0.0604 | 0.0675 | 0.1040 | 0.1154 | 0.0752 | 0.0819 | 0.1097 | 0.1185 | 0.6378 | 0.5984 | 0.0000 | 0.0001 | 0.0012 | 0.0086 | 0.0549 | 0.0904 | 0.0693 | 0.0991 | 0.6764 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 517 | 209 | 10942 | 35449 | 447.3 | 110.82 | 142.08 | 205.96 | 312 | 350 | 381 | 410 | 439 | 469 | 501 | 538 | 598 | 0.0363 | 1286 | 0.903 | 94.01 | 21.02 | 3 | 0.0206 | 225 | 0.0006 | 67.31 | 7.714 | 0.1503 | 212393.0 | 107000000 | 56200000000 | 31100000000000 | 0.4346 | 0.2214 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0049 | 0.0003 | 0.0220 | 0.0020 | 0.0807 | 0.0222 | 0.1586 | 0.0494 | 0.1521 | 0.0568 | 0.1699 | 0.0831 | 0.4104 | 0.7861 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0011 | 0.0001 | 0.0069 | 0.0010 | 0.0331 | 0.0142 | 0.0664 | 0.0263 | 0.0584 | 0.0248 | 0.0766 | 0.0387 | 0.7570 | 0.8948 | 0.0022 | 0.0069 | 0.0081 | 0.0139 | 0.0103 | 0.0416 | 0.0550 | 0.1150 | 0.1279 | 0.1967 | 0.1699 | 0.1884 | 0.1225 | 0.1177 | 0.1516 | 0.1399 | 0.3524 | 0.1801 | 0.0008 | 0.0008 | 0.0065 | 0.0223 | 0.0687 | 0.1106 | 0.0929 | 0.1244 | 0.5730 | 7 | 10 | 12 | 15 | 24 | 71 | 163 | 276 | 443 | 0.1042 | 31.77 | 4.906 | 0.5483 | 62607.4 | 38100000 | 28100000000 | 23900000000000 | 0.4712 | 0.1726 | 0.0362 | 0.0022 | 0.1614 | 0.0112 | 0.2304 | 0.0744 | 0.1585 | 0.1487 | 0.1473 | 0.1922 | 0.1121 | 0.1786 | 0.0662 | 0.1198 | 0.0498 | 0.1135 | 0.0382 | 0.1594 | 0.0002 | 0.0001 | 0.0002 | 0.0002 | 0.0007 | 0.0005 | 0.0067 | 0.0061 | 0.0345 | 0.0311 | 0.0658 | 0.0530 | 0.0462 | 0.0389 | 0.0718 | 0.0600 | 0.7738 | 0.8102 | 0.0000 | 0.0005 | 0.0006 | 0.0007 | 0.0010 | 0.0021 | 0.0102 | 0.0107 | 0.0492 | 0.0560 | 0.0855 | 0.0946 | 0.0637 | 0.0738 | 0.0966 | 0.1019 | 0.6933 | 0.6595 | 0.0002 | 0.0003 | 0.0018 | 0.0074 | 0.0431 | 0.0740 | 0.0560 | 0.0876 | 0.7297 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 394 | 413 | 10632 | 28722 | 169.7 | 54.58 | 192.66 | 182.13 | 104 | 123 | 136 | 150 | 164 | 180 | 197 | 216 | 243 | 0.0521 | 1497 | 0.576 | 118.81 | 23.02 | 3 | 0.0271 | 288 | 0.0008 | 43.75 | 7.350 | 0.1857 | 31777.4 | 6480000 | 1420000000 | 333000000000 | 0.4827 | 0.1836 | 0.0013 | 0.0000 | 0.0034 | 0.0005 | 0.0185 | 0.0025 | 0.0583 | 0.0094 | 0.1357 | 0.0376 | 0.2026 | 0.0859 | 0.1755 | 0.0911 | 0.1662 | 0.1246 | 0.2386 | 0.6485 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0027 | 0.0009 | 0.0142 | 0.0049 | 0.0416 | 0.0211 | 0.0761 | 0.0422 | 0.0667 | 0.0367 | 0.0911 | 0.0553 | 0.7060 | 0.8389 | 0.0022 | 0.0080 | 0.0032 | 0.0048 | 0.0097 | 0.0177 | 0.0479 | 0.1054 | 0.1186 | 0.1826 | 0.1586 | 0.1955 | 0.1287 | 0.1086 | 0.1536 | 0.1561 | 0.3774 | 0.2212 | 0.0008 | 0.0036 | 0.0069 | 0.0223 | 0.0674 | 0.1032 | 0.0931 | 0.1210 | 0.5817 | 24 | 38 | 60 | 93 | 133 | 183 | 247 | 329 | 451 | 0.0090 | 53.03 | 6.503 | 0.3348 | 70288.5 | 35100000 | 21300000000 | 14900000000000 | 0.4473 | 0.2023 | 0.0513 | 0.0009 | 0.1890 | 0.0115 | 0.2553 | 0.1069 | 0.1609 | 0.1443 | 0.1281 | 0.1866 | 0.0945 | 0.1921 | 0.0604 | 0.1246 | 0.0377 | 0.1011 | 0.0229 | 0.1320 | 0.0004 | 0.0002 | 0.0008 | 0.0006 | 0.0033 | 0.0030 | 0.0171 | 0.0128 | 0.0759 | 0.0579 | 0.1188 | 0.0951 | 0.0890 | 0.0750 | 0.1298 | 0.1102 | 0.5649 | 0.6452 | 0.0008 | 0.0009 | 0.0019 | 0.0028 | 0.0069 | 0.0116 | 0.0329 | 0.0449 | 0.1100 | 0.1226 | 0.1619 | 0.1747 | 0.1106 | 0.1143 | 0.1454 | 0.1490 | 0.4295 | 0.3791 | 0.0003 | 0.0015 | 0.0048 | 0.0246 | 0.0931 | 0.1422 | 0.1029 | 0.1420 | 0.4886 | |
MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 289 | 493 | 6798 | 23833 | 396.9 | 72.62 | 122.22 | 112.72 | 305 | 332 | 353 | 372 | 393 | 413 | 434 | 460 | 496 | 0.0457 | 1090 | 1.062 | 97.45 | 34.93 | 1 | 0.0374 | 254 | 0.0017 | 19.12 | 6.637 | 0.2476 | 162807.0 | 68900000 | 30000000000 | 13500000000000 | 0.3895 | 0.2520 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0023 | 0.0005 | 0.0107 | 0.0006 | 0.0469 | 0.0131 | 0.0916 | 0.0269 | 0.1033 | 0.0220 | 0.1432 | 0.0346 | 0.6015 | 0.9022 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0009 | 0.0003 | 0.0043 | 0.0003 | 0.0197 | 0.0111 | 0.0380 | 0.0209 | 0.0404 | 0.0105 | 0.0584 | 0.0164 | 0.8383 | 0.9404 | 0.0080 | 0.0227 | 0.0130 | 0.0455 | 0.0260 | 0.1136 | 0.0721 | 0.1212 | 0.1321 | 0.2045 | 0.1922 | 0.1515 | 0.1251 | 0.0985 | 0.1512 | 0.1061 | 0.2803 | 0.1364 | 0.0006 | 0.0018 | 0.0076 | 0.0223 | 0.0572 | 0.1036 | 0.0899 | 0.1253 | 0.5917 | 13 | 21 | 38 | 64 | 93 | 125 | 160 | 203 | 274 | 0.0273 | 9.30 | 5.190 | 0.4969 | 27642.2 | 8480000 | 3190000000 | 1400000000000 | 0.4768 | 0.1673 | 0.0272 | 0.0014 | 0.1103 | 0.0069 | 0.2030 | 0.0512 | 0.1793 | 0.1036 | 0.1586 | 0.1664 | 0.1277 | 0.1784 | 0.0836 | 0.1457 | 0.0699 | 0.1463 | 0.0404 | 0.2001 | 0.0004 | 0.0001 | 0.0012 | 0.0008 | 0.0030 | 0.0025 | 0.0136 | 0.0101 | 0.0526 | 0.0452 | 0.0989 | 0.0755 | 0.0730 | 0.0660 | 0.1124 | 0.0959 | 0.6447 | 0.7039 | 0.0012 | 0.0020 | 0.0031 | 0.0065 | 0.0092 | 0.0131 | 0.0290 | 0.0361 | 0.0788 | 0.0934 | 0.1280 | 0.1326 | 0.0965 | 0.1068 | 0.1320 | 0.1384 | 0.5220 | 0.4711 | 0.0005 | 0.0012 | 0.0038 | 0.0208 | 0.0676 | 0.1100 | 0.0939 | 0.1245 | 0.5777 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 834 | 433 | 10028 | 23515 | 170.4 | 45.07 | 251.81 | 223.41 | 116 | 130 | 142 | 154 | 167 | 180 | 195 | 212 | 231 | 0.0643 | 1511 | 0.433 | 138.81 | 20.40 | 4 | 0.0343 | 344 | 0.0006 | 58.13 | 7.696 | 0.1518 | 31076.2 | 6010000 | 1230000000 | 261000000000 | 0.4626 | 0.2012 | 0.0014 | 0.0001 | 0.0014 | 0.0000 | 0.0051 | 0.0010 | 0.0350 | 0.0070 | 0.1108 | 0.0315 | 0.1699 | 0.0658 | 0.1503 | 0.0658 | 0.1738 | 0.0971 | 0.3522 | 0.7316 | 0.0008 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0007 | 0.0127 | 0.0044 | 0.0411 | 0.0206 | 0.0636 | 0.0401 | 0.0541 | 0.0301 | 0.0732 | 0.0469 | 0.7527 | 0.8573 | 0.0016 | 0.0064 | 0.0036 | 0.0242 | 0.0121 | 0.0382 | 0.0395 | 0.1057 | 0.0999 | 0.1643 | 0.1386 | 0.1771 | 0.1185 | 0.1414 | 0.1350 | 0.1210 | 0.4512 | 0.2217 | 0.0013 | 0.0027 | 0.0055 | 0.0224 | 0.0554 | 0.0952 | 0.0829 | 0.1036 | 0.6310 | 27 | 65 | 104 | 142 | 188 | 246 | 318 | 410 | 550 | 0.0043 | 51.61 | 6.756 | 0.3199 | 113315.0 | 70500000 | 54700000000 | 49800000000000 | 0.5106 | 0.1551 | 0.0197 | 0.0009 | 0.0972 | 0.0050 | 0.2185 | 0.0351 | 0.1851 | 0.0833 | 0.1744 | 0.1635 | 0.1413 | 0.2193 | 0.0821 | 0.1599 | 0.0479 | 0.1407 | 0.0337 | 0.1922 | 0.0004 | 0.0003 | 0.0007 | 0.0007 | 0.0030 | 0.0032 | 0.0179 | 0.0117 | 0.0615 | 0.0449 | 0.0961 | 0.0795 | 0.0799 | 0.0637 | 0.0995 | 0.0868 | 0.6409 | 0.7092 | 0.0008 | 0.0013 | 0.0027 | 0.0038 | 0.0078 | 0.0110 | 0.0324 | 0.0428 | 0.0867 | 0.1042 | 0.1373 | 0.1566 | 0.0965 | 0.1074 | 0.1356 | 0.1445 | 0.5003 | 0.4284 | 0.0004 | 0.0017 | 0.0054 | 0.0273 | 0.0740 | 0.1165 | 0.0851 | 0.1169 | 0.5726 | |
Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 800 | 501 | 13792 | 38751 | 266.6 | 61.19 | 169.99 | 277.73 | 192 | 219 | 237 | 253 | 267 | 281 | 297 | 317 | 345 | 0.0391 | 1515 | 0.913 | 98.60 | 27.17 | 6 | 0.0188 | 259 | 0.0012 | 28.43 | 7.043 | 0.2221 | 74836.6 | 21900000 | 6660000000 | 2090000000000 | 0.4163 | 0.2227 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0034 | 0.0004 | 0.0145 | 0.0030 | 0.0508 | 0.0123 | 0.1000 | 0.0294 | 0.1083 | 0.0291 | 0.1428 | 0.0414 | 0.5789 | 0.8845 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0002 | 0.0051 | 0.0012 | 0.0181 | 0.0073 | 0.0381 | 0.0171 | 0.0415 | 0.0105 | 0.0570 | 0.0160 | 0.8387 | 0.9478 | 0.0032 | 0.0074 | 0.0083 | 0.0315 | 0.0221 | 0.0612 | 0.0437 | 0.1169 | 0.1095 | 0.1818 | 0.1536 | 0.1892 | 0.1312 | 0.1373 | 0.1276 | 0.1150 | 0.4009 | 0.1596 | 0.0001 | 0.0023 | 0.0069 | 0.0225 | 0.0520 | 0.0995 | 0.0920 | 0.1141 | 0.6107 | 11 | 14 | 16 | 21 | 32 | 62 | 139 | 285 | 553 | 0.1524 | 25.56 | 4.437 | 0.6078 | 106029.0 | 97600000 | 110000000000 | 141000000000000 | 0.3354 | 0.3305 | 0.0662 | 0.0027 | 0.2254 | 0.0240 | 0.2667 | 0.1419 | 0.1607 | 0.1818 | 0.1295 | 0.1818 | 0.0830 | 0.1829 | 0.0379 | 0.1071 | 0.0230 | 0.0916 | 0.0077 | 0.0861 | 0.0003 | 0.0003 | 0.0010 | 0.0006 | 0.0035 | 0.0021 | 0.0193 | 0.0153 | 0.0582 | 0.0549 | 0.0728 | 0.0726 | 0.0478 | 0.0442 | 0.0766 | 0.0719 | 0.7205 | 0.7381 | 0.0006 | 0.0007 | 0.0019 | 0.0018 | 0.0059 | 0.0059 | 0.0221 | 0.0258 | 0.0548 | 0.0602 | 0.0841 | 0.0861 | 0.0579 | 0.0644 | 0.0867 | 0.0924 | 0.6859 | 0.6628 | 0.0003 | 0.0015 | 0.0047 | 0.0221 | 0.0559 | 0.0766 | 0.0542 | 0.0790 | 0.7058 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 509 | 507 | 7824 | 25276 | 555.9 | 107.56 | 87.69 | 105.95 | 423 | 462 | 493 | 518 | 545 | 575 | 609 | 649 | 706 | 0.0436 | 1102 | 1.007 | 126.85 | 35.51 | 1 | 0.0387 | 303 | 0.0006 | 69.54 | 7.651 | 0.1417 | 320582.0 | 192000000 | 118000000000 | 75400000000000 | 0.3901 | 0.2585 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0078 | 0.0004 | 0.0495 | 0.0148 | 0.1105 | 0.0312 | 0.1156 | 0.0262 | 0.1566 | 0.0356 | 0.5585 | 0.8919 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0027 | 0.0000 | 0.0235 | 0.0112 | 0.0491 | 0.0226 | 0.0541 | 0.0132 | 0.0699 | 0.0177 | 0.7998 | 0.9352 | 0.0031 | 0.0092 | 0.0086 | 0.0323 | 0.0163 | 0.0276 | 0.0467 | 0.1198 | 0.1346 | 0.1935 | 0.1486 | 0.2166 | 0.1121 | 0.1106 | 0.1307 | 0.1290 | 0.3992 | 0.1613 | 0.0008 | 0.0025 | 0.0044 | 0.0227 | 0.0729 | 0.1111 | 0.1003 | 0.1279 | 0.5575 | 8 | 10 | 12 | 19 | 41 | 74 | 111 | 159 | 230 | 0.0557 | 17.43 | 5.062 | 0.4981 | 18913.8 | 5940000 | 2360000000 | 1110000000000 | 0.5214 | 0.1569 | 0.0217 | 0.0010 | 0.1318 | 0.0082 | 0.2484 | 0.0573 | 0.1624 | 0.1006 | 0.1628 | 0.1863 | 0.1092 | 0.2103 | 0.0691 | 0.1325 | 0.0507 | 0.1178 | 0.0438 | 0.1859 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0013 | 0.0003 | 0.0090 | 0.0059 | 0.0434 | 0.0366 | 0.0864 | 0.0707 | 0.0600 | 0.0485 | 0.0853 | 0.0637 | 0.7144 | 0.7741 | 0.0004 | 0.0001 | 0.0010 | 0.0009 | 0.0023 | 0.0038 | 0.0153 | 0.0204 | 0.0611 | 0.0695 | 0.1126 | 0.1258 | 0.0774 | 0.0886 | 0.1029 | 0.1191 | 0.6271 | 0.5718 | 0.0000 | 0.0001 | 0.0020 | 0.0125 | 0.0561 | 0.0967 | 0.0714 | 0.0968 | 0.6644 | |||
Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 798 | 428 | 27432 | 45118 | 211.1 | 59.97 | 98.82 | 173.21 | 140 | 162 | 179 | 194 | 208 | 223 | 239 | 258 | 287 | 0.0427 | 1927 | 0.804 | 104.04 | 21.19 | 1 | 0.0082 | 226 | 0.0007 | 43.54 | 7.545 | 0.1862 | 48158.5 | 11800000 | 3050000000 | 838000000000 | 0.4170 | 0.2298 | 0.0009 | 0.0000 | 0.0014 | 0.0001 | 0.0072 | 0.0005 | 0.0254 | 0.0026 | 0.0661 | 0.0188 | 0.1224 | 0.0410 | 0.1361 | 0.0439 | 0.1737 | 0.0674 | 0.4667 | 0.8259 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0001 | 0.0072 | 0.0009 | 0.0239 | 0.0093 | 0.0448 | 0.0189 | 0.0494 | 0.0177 | 0.0650 | 0.0292 | 0.8061 | 0.9239 | 0.0049 | 0.0049 | 0.0082 | 0.0175 | 0.0196 | 0.0265 | 0.0469 | 0.0746 | 0.0894 | 0.1169 | 0.1266 | 0.1677 | 0.1090 | 0.1102 | 0.1271 | 0.1250 | 0.4683 | 0.3566 | 0.0014 | 0.0023 | 0.0066 | 0.0227 | 0.0535 | 0.0917 | 0.0877 | 0.1135 | 0.6206 | 10 | 12 | 14 | 16 | 20 | 29 | 54 | 137 | 332 | 0.1819 | 23.17 | 3.891 | 0.6587 | 39767.1 | 24100000 | 17400000000 | 14100000000000 | 0.4082 | 0.2647 | 0.1462 | 0.0039 | 0.3078 | 0.0465 | 0.2795 | 0.2378 | 0.1040 | 0.2151 | 0.0818 | 0.2042 | 0.0463 | 0.1441 | 0.0206 | 0.0647 | 0.0093 | 0.0494 | 0.0046 | 0.0343 | 0.0000 | 0.0000 | 0.0009 | 0.0006 | 0.0015 | 0.0011 | 0.0142 | 0.0095 | 0.0704 | 0.0604 | 0.0987 | 0.0930 | 0.0678 | 0.0551 | 0.1104 | 0.0943 | 0.6360 | 0.6860 | 0.0003 | 0.0000 | 0.0017 | 0.0017 | 0.0033 | 0.0043 | 0.0185 | 0.0216 | 0.0848 | 0.0897 | 0.1211 | 0.1251 | 0.0804 | 0.0863 | 0.1188 | 0.1212 | 0.5710 | 0.5502 | 0.0001 | 0.0006 | 0.0030 | 0.0167 | 0.0751 | 0.1185 | 0.0740 | 0.1117 | 0.6002 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1089 | 808 | 9170 | 24605 | 276.9 | 78.28 | 148.86 | 243.52 | 189 | 217 | 236 | 252 | 269 | 287 | 308 | 335 | 379 | 0.0478 | 1177 | 0.975 | 178.47 | 49.01 | 3 | 0.0484 | 444 | 0.0005 | 83.21 | 7.806 | 0.1414 | 82817.9 | 26600000 | 9120000000 | 3340000000000 | 0.3821 | 0.2526 | 0.0006 | 0.0000 | 0.0006 | 0.0003 | 0.0050 | 0.0006 | 0.0193 | 0.0027 | 0.0640 | 0.0215 | 0.1201 | 0.0404 | 0.1246 | 0.0400 | 0.1755 | 0.0620 | 0.4903 | 0.8326 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0081 | 0.0007 | 0.0235 | 0.0104 | 0.0451 | 0.0203 | 0.0512 | 0.0147 | 0.0759 | 0.0249 | 0.7939 | 0.9289 | 0.0042 | 0.0025 | 0.0052 | 0.0076 | 0.0157 | 0.0290 | 0.0408 | 0.0718 | 0.0963 | 0.1272 | 0.1387 | 0.1348 | 0.0994 | 0.1083 | 0.1251 | 0.1486 | 0.4746 | 0.3703 | 0.0014 | 0.0038 | 0.0107 | 0.0227 | 0.0568 | 0.0940 | 0.0838 | 0.1095 | 0.6172 | 10 | 13 | 15 | 19 | 31 | 61 | 125 | 239 | 462 | 0.0836 | 33.10 | 4.848 | 0.5636 | 81459.4 | 66300000 | 65000000000 | 71600000000000 | 0.3987 | 0.2387 | 0.0508 | 0.0023 | 0.1457 | 0.0182 | 0.2453 | 0.0872 | 0.1798 | 0.1196 | 0.1631 | 0.1870 | 0.1009 | 0.1877 | 0.0602 | 0.1413 | 0.0328 | 0.1066 | 0.0214 | 0.1501 | 0.0005 | 0.0000 | 0.0012 | 0.0005 | 0.0030 | 0.0019 | 0.0118 | 0.0111 | 0.0408 | 0.0392 | 0.0780 | 0.0652 | 0.0537 | 0.0500 | 0.0809 | 0.0683 | 0.7301 | 0.7639 | 0.0008 | 0.0004 | 0.0010 | 0.0022 | 0.0038 | 0.0053 | 0.0155 | 0.0224 | 0.0573 | 0.0634 | 0.0994 | 0.0936 | 0.0692 | 0.0729 | 0.0878 | 0.0951 | 0.6653 | 0.6447 | 0.0003 | 0.0010 | 0.0025 | 0.0126 | 0.0505 | 0.0841 | 0.0681 | 0.0859 | 0.6949 |