High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 212 | 744 | | 6614 | 10325 | 163.1 | 32.35 | 119.28 | 84.78 | 125 | 138 | 147 | 155 | 161 | 167 | 175 | 185 | 203 | 0.0792 | 818 | 1.172 | 127.35 | 40.25 | 1 | 0.0452 | 299 | 0.0020 | 27.70 | 6.559 | 0.2300 | 27650.6 | 4880000 | 902000000 | 175000000000 | 0.4500 | 0.2031 | 0.0002 | 0.0000 | 0.0008 | 0.0003 | 0.0033 | 0.0005 | 0.0157 | 0.0009 | 0.0518 | 0.0158 | 0.1045 | 0.0311 | 0.1239 | 0.0356 | 0.1680 | 0.0538 | 0.5318 | 0.8621 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0073 | 0.0005 | 0.0238 | 0.0110 | 0.0514 | 0.0224 | 0.0550 | 0.0146 | 0.0835 | 0.0286 | 0.7771 | 0.9229 | 0.0114 | 0.0090 | 0.0194 | 0.0495 | 0.0411 | 0.0495 | 0.1006 | 0.1802 | 0.1600 | 0.2117 | 0.1794 | 0.1757 | 0.1486 | 0.0991 | 0.1394 | 0.0991 | 0.2000 | 0.1261 | 0.0006 | 0.0063 | 0.0157 | 0.0466 | 0.0913 | 0.1326 | 0.1222 | 0.1698 | 0.4148 | 30 | 47 | 62 | 79 | 97 | 119 | 148 | 185 | 240 | 0.0026 | 32.10 | 6.579 | 0.2832 | 21415.5 | 4970000 | 1370000000 | 425000000000 | 0.5726 | 0.1051 | 0.0233 | 0.0012 | 0.1341 | 0.0059 | 0.2743 | 0.0446 | 0.1832 | 0.1006 | 0.1522 | 0.1877 | 0.1071 | 0.1954 | 0.0694 | 0.1475 | 0.0367 | 0.1460 | 0.0197 | 0.1709 | 0.0004 | 0.0005 | 0.0023 | 0.0009 | 0.0082 | 0.0027 | 0.0218 | 0.0148 | 0.0827 | 0.0624 | 0.1269 | 0.0968 | 0.1019 | 0.0859 | 0.1392 | 0.1237 | 0.5166 | 0.6124 | 0.0015 | 0.0023 | 0.0073 | 0.0051 | 0.0094 | 0.0167 | 0.0462 | 0.0607 | 0.1152 | 0.1293 | 0.1711 | 0.1795 | 0.1100 | 0.1215 | 0.1510 | 0.1484 | 0.3883 | 0.3364 | 0.0007 | 0.0041 | 0.0070 | 0.0374 | 0.0934 | 0.1539 | 0.1074 | 0.1421 | 0.4540 | ||
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 925 | 483 | | 3069 | 17112 | 133.0 | 40.22 | 103.86 | 203.05 | 76 | 97 | 114 | 125 | 135 | 144 | 156 | 169 | 185 | 0.0464 | 794 | 0.346 | 113.00 | 13.45 | 1 | 0.1036 | 318 | 0.0020 | 15.03 | 6.464 | 0.2683 | 19308.7 | 2990000 | 486000000 | 82200000000 | 0.3770 | 0.2497 | 0.0000 | 0.0000 | 0.0061 | 0.0008 | 0.0067 | 0.0008 | 0.0223 | 0.0066 | 0.0756 | 0.0370 | 0.1201 | 0.0555 | 0.1066 | 0.0588 | 0.1296 | 0.0867 | 0.5331 | 0.7538 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0004 | 0.0004 | 0.0065 | 0.0033 | 0.0230 | 0.0218 | 0.0390 | 0.0336 | 0.0295 | 0.0251 | 0.0464 | 0.0369 | 0.8553 | 0.8783 | 0.0000 | 0.0072 | 0.0036 | 0.0036 | 0.0109 | 0.0324 | 0.0339 | 0.0755 | 0.0593 | 0.1547 | 0.1186 | 0.1007 | 0.1005 | 0.1583 | 0.1223 | 0.1151 | 0.5508 | 0.3525 | 0.0006 | 0.0006 | 0.0031 | 0.0161 | 0.0433 | 0.0644 | 0.0718 | 0.0934 | 0.7067 | 11 | 13 | 16 | 21 | 29 | 46 | 76 | 134 | 243 | 0.0626 | 20.97 | 4.597 | 0.5710 | 52014.4 | 50700000 | 63400000000 | 88800000000000 | 0.5552 | 0.1464 | 0.0385 | 0.0020 | 0.1709 | 0.0137 | 0.2873 | 0.1186 | 0.1533 | 0.1182 | 0.1415 | 0.1703 | 0.1114 | 0.2121 | 0.0427 | 0.1186 | 0.0369 | 0.1014 | 0.0176 | 0.1452 | 0.0004 | 0.0007 | 0.0010 | 0.0017 | 0.0045 | 0.0040 | 0.0170 | 0.0154 | 0.0622 | 0.0508 | 0.1379 | 0.1125 | 0.0614 | 0.0648 | 0.0821 | 0.0786 | 0.6335 | 0.6716 | 0.0014 | 0.0009 | 0.0049 | 0.0060 | 0.0140 | 0.0158 | 0.0198 | 0.0211 | 0.0673 | 0.0687 | 0.1389 | 0.1378 | 0.0579 | 0.0627 | 0.0826 | 0.0880 | 0.6132 | 0.5990 | 0.0005 | 0.0036 | 0.0082 | 0.0192 | 0.0694 | 0.1387 | 0.0634 | 0.0742 | 0.6229 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1036 | 656 | | 6909 | 17984 | 410.6 | 89.98 | 149.03 | 156.51 | 291 | 332 | 361 | 387 | 409 | 432 | 457 | 486 | 536 | 0.0622 | 1118 | 0.898 | 69.57 | 17.20 | 1 | 0.0248 | 171 | 0.0008 | 36.78 | 7.401 | 0.1966 | 176674.0 | 79200000 | 36900000000 | 17700000000000 | 0.4312 | 0.2120 | 0.0007 | 0.0000 | 0.0016 | 0.0002 | 0.0034 | 0.0005 | 0.0108 | 0.0020 | 0.0391 | 0.0147 | 0.0913 | 0.0355 | 0.0855 | 0.0290 | 0.1133 | 0.0461 | 0.6543 | 0.8720 | 0.0004 | 0.0000 | 0.0004 | 0.0001 | 0.0025 | 0.0000 | 0.0034 | 0.0009 | 0.0166 | 0.0112 | 0.0378 | 0.0207 | 0.0314 | 0.0124 | 0.0448 | 0.0203 | 0.8629 | 0.9343 | 0.0032 | 0.0000 | 0.0080 | 0.0000 | 0.0135 | 0.0000 | 0.0358 | 0.0000 | 0.0923 | 0.0000 | 0.1146 | 0.0000 | 0.0819 | 0.0000 | 0.1233 | 0.0000 | 0.5274 | 0.0000 | 0.0006 | 0.0024 | 0.0059 | 0.0221 | 0.0489 | 0.0734 | 0.0681 | 0.0943 | 0.6844 | 11 | 14 | 25 | 52 | 91 | 138 | 202 | 281 | 382 | 0.0546 | 17.50 | 5.311 | 0.5113 | 46702.5 | 19100000 | 9060000000 | 4790000000000 | 0.5773 | 0.1082 | 0.0176 | 0.0024 | 0.0828 | 0.0099 | 0.1823 | 0.0387 | 0.1855 | 0.0739 | 0.1780 | 0.1442 | 0.1507 | 0.1991 | 0.0866 | 0.1416 | 0.0663 | 0.1505 | 0.0502 | 0.2396 | 0.0004 | 0.0002 | 0.0013 | 0.0009 | 0.0018 | 0.0020 | 0.0098 | 0.0055 | 0.0367 | 0.0299 | 0.0651 | 0.0490 | 0.0517 | 0.0398 | 0.0765 | 0.0650 | 0.7568 | 0.8077 | 0.0005 | 0.0006 | 0.0005 | 0.0012 | 0.0035 | 0.0038 | 0.0112 | 0.0175 | 0.0539 | 0.0691 | 0.1009 | 0.1110 | 0.0752 | 0.0900 | 0.1122 | 0.1267 | 0.6422 | 0.5802 | 0.0003 | 0.0004 | 0.0029 | 0.0108 | 0.0469 | 0.0779 | 0.0647 | 0.0975 | 0.6985 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 593 | 809 | | 9054 | 36760 | 386.6 | 78.38 | 181.80 | 168.48 | 283 | 319 | 345 | 368 | 389 | 408 | 428 | 453 | 485 | 0.0343 | 1261 | 1.172 | 117.32 | 46.07 | 2 | 0.0357 | 323 | 0.0013 | 28.99 | 6.930 | 0.2068 | 155613.0 | 64900000 | 28000000000 | 12400000000000 | 0.4514 | 0.1993 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0031 | 0.0000 | 0.0122 | 0.0006 | 0.0609 | 0.0126 | 0.1366 | 0.0323 | 0.1416 | 0.0335 | 0.1674 | 0.0533 | 0.4776 | 0.8677 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0025 | 0.0000 | 0.0256 | 0.0110 | 0.0577 | 0.0252 | 0.0556 | 0.0184 | 0.0717 | 0.0277 | 0.7858 | 0.9178 | 0.0076 | 0.0205 | 0.0124 | 0.1231 | 0.0275 | 0.0923 | 0.0927 | 0.1282 | 0.1683 | 0.1692 | 0.1999 | 0.1538 | 0.1484 | 0.0974 | 0.1374 | 0.1077 | 0.2060 | 0.1077 | 0.0006 | 0.0009 | 0.0039 | 0.0214 | 0.0744 | 0.1309 | 0.1084 | 0.1493 | 0.5102 | 20 | 40 | 70 | 101 | 134 | 175 | 226 | 293 | 410 | 0.0090 | 24.30 | 6.122 | 0.3733 | 61436.3 | 29700000 | 18600000000 | 14600000000000 | 0.4309 | 0.1918 | 0.0224 | 0.0007 | 0.1034 | 0.0058 | 0.2259 | 0.0487 | 0.1796 | 0.0900 | 0.1556 | 0.1611 | 0.1385 | 0.1955 | 0.0838 | 0.1496 | 0.0540 | 0.1427 | 0.0368 | 0.2058 | 0.0002 | 0.0003 | 0.0014 | 0.0006 | 0.0040 | 0.0027 | 0.0165 | 0.0104 | 0.0562 | 0.0443 | 0.1108 | 0.0905 | 0.0855 | 0.0719 | 0.1171 | 0.1021 | 0.6083 | 0.6773 | 0.0012 | 0.0016 | 0.0027 | 0.0043 | 0.0087 | 0.0124 | 0.0274 | 0.0393 | 0.0838 | 0.0961 | 0.1402 | 0.1499 | 0.1102 | 0.1133 | 0.1381 | 0.1378 | 0.4877 | 0.4453 | 0.0006 | 0.0015 | 0.0052 | 0.0174 | 0.0731 | 0.1259 | 0.1003 | 0.1286 | 0.5475 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 740 | 703 | | 8862 | 18824 | 530.1 | 80.43 | 114.15 | 251.56 | 421 | 467 | 496 | 517 | 535 | 553 | 573 | 598 | 631 | 0.0548 | 1032 | 0.545 | 114.22 | 22.67 | 5 | 0.0372 | 330 | 0.0009 | 38.41 | 7.314 | 0.2073 | 287452.0 | 159000000 | 89500000000 | 51200000000000 | 0.4491 | 0.2025 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0007 | 0.0001 | 0.0056 | 0.0007 | 0.0282 | 0.0139 | 0.0564 | 0.0200 | 0.0512 | 0.0144 | 0.0715 | 0.0211 | 0.7858 | 0.9298 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0016 | 0.0007 | 0.0179 | 0.0139 | 0.0306 | 0.0200 | 0.0252 | 0.0144 | 0.0335 | 0.0202 | 0.8913 | 0.9307 | 0.0075 | 1.0000 | 0.0188 | 0.0000 | 0.0225 | 0.0000 | 0.0476 | 0.0000 | 0.1164 | 0.0000 | 0.1640 | 0.0000 | 0.1014 | 0.0000 | 0.1502 | 0.0000 | 0.3717 | 0.0000 | 0.0006 | 0.0036 | 0.0074 | 0.0181 | 0.0434 | 0.0613 | 0.0734 | 0.0863 | 0.7059 | 9 | 10 | 12 | 13 | 15 | 20 | 38 | 121 | 352 | 0.1429 | 9.00 | 3.049 | 0.5952 | 76308.2 | 79500000 | 99600000000 | 139000000000000 | 0.5235 | 0.1294 | 0.0259 | 0.0023 | 0.0761 | 0.0164 | 0.2120 | 0.0561 | 0.1942 | 0.0865 | 0.2006 | 0.1645 | 0.1003 | 0.2050 | 0.1036 | 0.1458 | 0.0631 | 0.1341 | 0.0243 | 0.1894 | 0.0000 | 0.0004 | 0.0002 | 0.0004 | 0.0012 | 0.0011 | 0.0067 | 0.0072 | 0.0396 | 0.0383 | 0.0538 | 0.0475 | 0.0401 | 0.0385 | 0.0569 | 0.0591 | 0.8015 | 0.8073 | 0.0003 | 0.0000 | 0.0006 | 0.0006 | 0.0017 | 0.0021 | 0.0056 | 0.0079 | 0.0476 | 0.0539 | 0.0673 | 0.0667 | 0.0437 | 0.0521 | 0.0707 | 0.0758 | 0.7625 | 0.7409 | 0.0000 | 0.0005 | 0.0016 | 0.0065 | 0.0428 | 0.0586 | 0.0418 | 0.0664 | 0.7819 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1040 | 910 | | 3585 | 10231 | 344.3 | 84.59 | 34.10 | 76.86 | 243 | 270 | 294 | 317 | 338 | 360 | 384 | 412 | 458 | 0.0777 | 795 | 0.975 | 80.16 | 26.08 | 1 | 0.0555 | 199 | 0.0010 | 48.18 | 7.091 | 0.1715 | 125705.0 | 48500000 | 19700000000 | 8380000000000 | 0.4417 | 0.2214 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0058 | 0.0006 | 0.0346 | 0.0056 | 0.1029 | 0.0262 | 0.1587 | 0.0586 | 0.1640 | 0.0586 | 0.1722 | 0.0873 | 0.3583 | 0.7630 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0014 | 0.0006 | 0.0122 | 0.0029 | 0.0480 | 0.0161 | 0.0735 | 0.0365 | 0.0724 | 0.0276 | 0.0882 | 0.0419 | 0.7031 | 0.8745 | 0.0056 | 0.0041 | 0.0014 | 0.0331 | 0.0324 | 0.0455 | 0.0606 | 0.0909 | 0.1437 | 0.2066 | 0.1521 | 0.1901 | 0.1211 | 0.1116 | 0.1563 | 0.1570 | 0.3268 | 0.1612 | 0.0006 | 0.0041 | 0.0094 | 0.0241 | 0.0700 | 0.1329 | 0.0988 | 0.1424 | 0.5176 | 5 | 6 | 6 | 8 | 9 | 10 | 14 | 28 | 84 | 0.2835 | 3.77 | 2.562 | 0.7553 | 7069.4 | 2850000 | 1600000000 | 1100000000000 | 0.6411 | 0.0755 | 0.0751 | 0.0073 | 0.1503 | 0.0125 | 0.2306 | 0.0658 | 0.2098 | 0.1524 | 0.1710 | 0.1994 | 0.0984 | 0.1754 | 0.0492 | 0.1242 | 0.0130 | 0.1420 | 0.0026 | 0.1211 | 0.0063 | 0.0020 | 0.0073 | 0.0041 | 0.0078 | 0.0138 | 0.0195 | 0.0292 | 0.0640 | 0.0604 | 0.0762 | 0.0835 | 0.0703 | 0.0722 | 0.0996 | 0.1078 | 0.6489 | 0.6271 | 0.0012 | 0.0040 | 0.0030 | 0.0020 | 0.0084 | 0.0080 | 0.0247 | 0.0172 | 0.0596 | 0.0669 | 0.0915 | 0.0948 | 0.0686 | 0.0749 | 0.1113 | 0.1021 | 0.6318 | 0.6302 | 0.0027 | 0.0027 | 0.0092 | 0.0223 | 0.0566 | 0.0886 | 0.0691 | 0.1033 | 0.6455 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 420 | 742 | | 10935 | 36965 | 570.5 | 116.52 | 204.39 | 357.85 | 434 | 472 | 502 | 530 | 557 | 586 | 619 | 663 | 727 | 0.0445 | 1646 | 1.010 | 102.55 | 38.05 | 2 | 0.0258 | 282 | 0.0006 | 81.76 | 7.769 | 0.1488 | 339006.0 | 210000000 | 136000000000 | 92000000000000 | 0.4191 | 0.2288 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0035 | 0.0003 | 0.0113 | 0.0011 | 0.0543 | 0.0126 | 0.1116 | 0.0285 | 0.1155 | 0.0282 | 0.1447 | 0.0456 | 0.5584 | 0.8837 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0039 | 0.0003 | 0.0256 | 0.0086 | 0.0516 | 0.0165 | 0.0554 | 0.0121 | 0.0712 | 0.0199 | 0.7907 | 0.9426 | 0.0034 | 0.0123 | 0.0069 | 0.0369 | 0.0195 | 0.0541 | 0.0653 | 0.1253 | 0.1146 | 0.1695 | 0.1725 | 0.1892 | 0.1135 | 0.0983 | 0.1358 | 0.1007 | 0.3685 | 0.2138 | 0.0006 | 0.0044 | 0.0105 | 0.0277 | 0.0720 | 0.1148 | 0.0938 | 0.1191 | 0.5571 | 6 | 8 | 9 | 11 | 14 | 35 | 134 | 381 | 754 | 0.1781 | 65.60 | 4.468 | 0.5873 | 169829.0 | 188000000 | 243000000000 | 352000000000000 | 0.4094 | 0.2312 | 0.1194 | 0.0037 | 0.3132 | 0.0514 | 0.3248 | 0.2365 | 0.1171 | 0.2139 | 0.0620 | 0.1913 | 0.0302 | 0.1403 | 0.0225 | 0.0740 | 0.0078 | 0.0503 | 0.0031 | 0.0385 | 0.0000 | 0.0000 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0066 | 0.0033 | 0.0399 | 0.0364 | 0.0767 | 0.0693 | 0.0521 | 0.0427 | 0.0787 | 0.0708 | 0.7456 | 0.7764 | 0.0000 | 0.0000 | 0.0001 | 0.0003 | 0.0010 | 0.0015 | 0.0075 | 0.0101 | 0.0502 | 0.0538 | 0.0946 | 0.1037 | 0.0644 | 0.0702 | 0.0978 | 0.1071 | 0.6844 | 0.6533 | 0.0000 | 0.0002 | 0.0006 | 0.0068 | 0.0462 | 0.0827 | 0.0597 | 0.0911 | 0.7127 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 372 | 900 | | 5044 | 9324 | 570.5 | 98.09 | 110.30 | 193.81 | 423 | 504 | 548 | 574 | 591 | 608 | 625 | 644 | 675 | 0.0741 | 691 | 0.949 | 144.16 | 41.87 | 3 | 0.0765 | 386 | 0.0009 | 58.08 | 7.313 | 0.1858 | 335121.0 | 201000000 | 123000000000 | 76200000000000 | 0.4530 | 0.1918 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0002 | 0.0055 | 0.0012 | 0.0271 | 0.0139 | 0.0472 | 0.0212 | 0.0462 | 0.0133 | 0.0650 | 0.0234 | 0.8066 | 0.9268 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0018 | 0.0012 | 0.0148 | 0.0139 | 0.0237 | 0.0212 | 0.0189 | 0.0133 | 0.0283 | 0.0218 | 0.9121 | 0.9285 | 0.0051 | 1.0000 | 0.0204 | 0.0000 | 0.0382 | 0.0000 | 0.0789 | 0.0000 | 0.1399 | 0.0000 | 0.1527 | 0.0000 | 0.1425 | 0.0000 | 0.1552 | 0.0000 | 0.2672 | 0.0000 | 0.0006 | 0.0016 | 0.0039 | 0.0132 | 0.0319 | 0.0631 | 0.0673 | 0.0879 | 0.7304 | 13 | 15 | 17 | 20 | 24 | 37 | 65 | 143 | 347 | 0.2499 | 4.68 | 3.068 | 0.7533 | 49725.0 | 35000000 | 30000000000 | 29200000000000 | 0.6863 | 0.0611 | 0.0201 | 0.0070 | 0.0828 | 0.0120 | 0.2081 | 0.0468 | 0.1834 | 0.0807 | 0.1969 | 0.1723 | 0.1454 | 0.1912 | 0.0805 | 0.1524 | 0.0403 | 0.1404 | 0.0425 | 0.1972 | 0.0004 | 0.0022 | 0.0004 | 0.0022 | 0.0021 | 0.0065 | 0.0116 | 0.0151 | 0.0418 | 0.0391 | 0.0708 | 0.0613 | 0.0472 | 0.0459 | 0.0911 | 0.0911 | 0.7345 | 0.7368 | 0.0000 | 0.0006 | 0.0005 | 0.0006 | 0.0051 | 0.0011 | 0.0142 | 0.0146 | 0.0524 | 0.0611 | 0.0956 | 0.0952 | 0.0478 | 0.0538 | 0.0935 | 0.0947 | 0.6909 | 0.6784 | 0.0000 | 0.0000 | 0.0019 | 0.0116 | 0.0551 | 0.0811 | 0.0487 | 0.0982 | 0.7034 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 352 | 145 | | 6842 | 23190 | 516.1 | 88.93 | 82.73 | 76.82 | 394 | 442 | 473 | 497 | 519 | 540 | 560 | 588 | 626 | 0.0471 | 1092 | 1.217 | 112.40 | 44.05 | 1 | 0.0417 | 285 | 0.0008 | 51.79 | 7.367 | 0.1654 | 274282.0 | 150000000 | 83800000000 | 48000000000000 | 0.4133 | 0.2357 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0000 | 0.0068 | 0.0009 | 0.0395 | 0.0128 | 0.0867 | 0.0244 | 0.0880 | 0.0204 | 0.1257 | 0.0318 | 0.6515 | 0.9098 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0001 | 0.0219 | 0.0112 | 0.0469 | 0.0212 | 0.0429 | 0.0121 | 0.0560 | 0.0240 | 0.8305 | 0.9315 | 0.0064 | 0.0000 | 0.0244 | 0.0385 | 0.0450 | 0.1538 | 0.0720 | 0.1795 | 0.1362 | 0.1538 | 0.1542 | 0.1923 | 0.1105 | 0.1538 | 0.1041 | 0.0769 | 0.3470 | 0.0513 | 0.0006 | 0.0014 | 0.0071 | 0.0246 | 0.0801 | 0.1194 | 0.1251 | 0.1398 | 0.5020 | 13 | 21 | 33 | 47 | 63 | 80 | 100 | 127 | 174 | 0.0136 | 7.65 | 5.221 | 0.4945 | 12746.0 | 3030000 | 998000000 | 416000000000 | 0.4776 | 0.1511 | 0.0127 | 0.0009 | 0.0661 | 0.0029 | 0.1634 | 0.0253 | 0.1896 | 0.0621 | 0.2119 | 0.1354 | 0.1531 | 0.1850 | 0.1031 | 0.1644 | 0.0654 | 0.1703 | 0.0348 | 0.2537 | 0.0006 | 0.0001 | 0.0017 | 0.0006 | 0.0053 | 0.0027 | 0.0178 | 0.0129 | 0.0589 | 0.0423 | 0.0902 | 0.0637 | 0.0775 | 0.0651 | 0.1124 | 0.0898 | 0.6356 | 0.7229 | 0.0024 | 0.0026 | 0.0024 | 0.0051 | 0.0088 | 0.0130 | 0.0336 | 0.0403 | 0.0825 | 0.0987 | 0.1329 | 0.1479 | 0.1037 | 0.1076 | 0.1323 | 0.1377 | 0.5013 | 0.4472 | 0.0009 | 0.0038 | 0.0065 | 0.0246 | 0.0676 | 0.1127 | 0.0949 | 0.1192 | 0.5699 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 619 | 317 | | 7410 | 29983 | 364.7 | 86.29 | 152.06 | 265.97 | 260 | 289 | 313 | 336 | 358 | 380 | 405 | 434 | 477 | 0.0351 | 1051 | 1.206 | 108.37 | 43.84 | 1 | 0.0379 | 281 | 0.0006 | 87.06 | 7.645 | 0.1436 | 140416.0 | 57000000 | 24300000000 | 10900000000000 | 0.4464 | 0.2073 | 0.0005 | 0.0000 | 0.0018 | 0.0001 | 0.0086 | 0.0001 | 0.0271 | 0.0018 | 0.0873 | 0.0187 | 0.1534 | 0.0482 | 0.1532 | 0.0439 | 0.1846 | 0.0654 | 0.3836 | 0.8218 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0001 | 0.0081 | 0.0003 | 0.0365 | 0.0110 | 0.0711 | 0.0286 | 0.0684 | 0.0204 | 0.0949 | 0.0311 | 0.7198 | 0.9085 | 0.0050 | 0.0092 | 0.0093 | 0.0297 | 0.0328 | 0.0343 | 0.0734 | 0.0847 | 0.1290 | 0.1533 | 0.1917 | 0.2197 | 0.1226 | 0.1327 | 0.1347 | 0.1373 | 0.3015 | 0.1991 | 0.0006 | 0.0026 | 0.0110 | 0.0266 | 0.0747 | 0.1389 | 0.1155 | 0.1259 | 0.5043 | 7 | 9 | 11 | 13 | 20 | 43 | 110 | 258 | 517 | 0.1512 | 39.36 | 4.482 | 0.5817 | 93855.6 | 84800000 | 94200000000 | 120000000000000 | 0.4152 | 0.1980 | 0.0734 | 0.0021 | 0.2052 | 0.0259 | 0.2539 | 0.1687 | 0.1640 | 0.1542 | 0.1373 | 0.1932 | 0.0879 | 0.1763 | 0.0480 | 0.1107 | 0.0165 | 0.0824 | 0.0137 | 0.0866 | 0.0000 | 0.0002 | 0.0007 | 0.0005 | 0.0021 | 0.0003 | 0.0100 | 0.0059 | 0.0491 | 0.0469 | 0.0856 | 0.0756 | 0.0537 | 0.0477 | 0.0753 | 0.0702 | 0.7236 | 0.7526 | 0.0003 | 0.0001 | 0.0018 | 0.0006 | 0.0017 | 0.0025 | 0.0090 | 0.0096 | 0.0589 | 0.0634 | 0.0991 | 0.1035 | 0.0632 | 0.0706 | 0.0877 | 0.0978 | 0.6783 | 0.6519 | 0.0001 | 0.0011 | 0.0020 | 0.0119 | 0.0542 | 0.0904 | 0.0605 | 0.0819 | 0.6977 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1250 | 480 | | 6010 | 16284 | 271.9 | 68.74 | 353.07 | 523.57 | 175 | 224 | 245 | 264 | 279 | 293 | 309 | 328 | 354 | 0.0591 | 962 | 1.159 | 131.22 | 44.78 | 2 | 0.0542 | 326 | 0.0013 | 30.49 | 7.001 | 0.2258 | 78643.6 | 23800000 | 7440000000 | 2400000000000 | 0.4018 | 0.2328 | 0.0008 | 0.0000 | 0.0022 | 0.0004 | 0.0030 | 0.0013 | 0.0170 | 0.0019 | 0.0460 | 0.0171 | 0.0930 | 0.0344 | 0.1038 | 0.0340 | 0.1408 | 0.0511 | 0.5934 | 0.8598 | 0.0002 | 0.0000 | 0.0002 | 0.0002 | 0.0002 | 0.0005 | 0.0026 | 0.0011 | 0.0142 | 0.0116 | 0.0318 | 0.0207 | 0.0259 | 0.0136 | 0.0451 | 0.0223 | 0.8798 | 0.9300 | 0.0040 | 0.0119 | 0.0161 | 0.0357 | 0.0185 | 0.0238 | 0.0611 | 0.1111 | 0.0957 | 0.1905 | 0.1262 | 0.1905 | 0.1294 | 0.1349 | 0.1455 | 0.1706 | 0.4035 | 0.1310 | 0.0006 | 0.0009 | 0.0061 | 0.0148 | 0.0439 | 0.0742 | 0.0805 | 0.1147 | 0.6642 | 9 | 12 | 15 | 20 | 33 | 124 | 394 | 769 | 1226 | 0.0716 | 108.75 | 5.493 | 0.4880 | 398768.0 | 556000000 | 859000000000 | 1.42E+15 | 0.4180 | 0.2363 | 0.0593 | 0.0007 | 0.2062 | 0.0235 | 0.3032 | 0.1478 | 0.1442 | 0.1457 | 0.1078 | 0.1974 | 0.0876 | 0.1807 | 0.0499 | 0.1175 | 0.0337 | 0.0960 | 0.0081 | 0.0907 | 0.0000 | 0.0000 | 0.0004 | 0.0003 | 0.0016 | 0.0009 | 0.0066 | 0.0043 | 0.0421 | 0.0372 | 0.0706 | 0.0656 | 0.0492 | 0.0439 | 0.0706 | 0.0630 | 0.7590 | 0.7848 | 0.0002 | 0.0002 | 0.0019 | 0.0018 | 0.0028 | 0.0030 | 0.0118 | 0.0149 | 0.0476 | 0.0557 | 0.0800 | 0.0896 | 0.0607 | 0.0667 | 0.0891 | 0.0875 | 0.7059 | 0.6807 | 0.0004 | 0.0010 | 0.0028 | 0.0079 | 0.0436 | 0.0772 | 0.0515 | 0.0798 | 0.7360 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 289 | 493 | | 6798 | 23833 | 396.9 | 72.62 | 122.22 | 112.72 | 305 | 332 | 353 | 372 | 393 | 413 | 434 | 460 | 496 | 0.0457 | 1090 | 1.062 | 97.45 | 34.93 | 1 | 0.0374 | 254 | 0.0017 | 19.12 | 6.637 | 0.2476 | 162807.0 | 68900000 | 30000000000 | 13500000000000 | 0.3895 | 0.2520 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0023 | 0.0005 | 0.0107 | 0.0006 | 0.0469 | 0.0131 | 0.0916 | 0.0269 | 0.1033 | 0.0220 | 0.1432 | 0.0346 | 0.6015 | 0.9022 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0009 | 0.0003 | 0.0043 | 0.0003 | 0.0197 | 0.0111 | 0.0380 | 0.0209 | 0.0404 | 0.0105 | 0.0584 | 0.0164 | 0.8383 | 0.9404 | 0.0080 | 0.0227 | 0.0130 | 0.0455 | 0.0260 | 0.1136 | 0.0721 | 0.1212 | 0.1321 | 0.2045 | 0.1922 | 0.1515 | 0.1251 | 0.0985 | 0.1512 | 0.1061 | 0.2803 | 0.1364 | 0.0006 | 0.0018 | 0.0076 | 0.0223 | 0.0572 | 0.1036 | 0.0899 | 0.1253 | 0.5917 | 13 | 21 | 38 | 64 | 93 | 125 | 160 | 203 | 274 | 0.0273 | 9.30 | 5.190 | 0.4969 | 27642.2 | 8480000 | 3190000000 | 1400000000000 | 0.4768 | 0.1673 | 0.0272 | 0.0014 | 0.1103 | 0.0069 | 0.2030 | 0.0512 | 0.1793 | 0.1036 | 0.1586 | 0.1664 | 0.1277 | 0.1784 | 0.0836 | 0.1457 | 0.0699 | 0.1463 | 0.0404 | 0.2001 | 0.0004 | 0.0001 | 0.0012 | 0.0008 | 0.0030 | 0.0025 | 0.0136 | 0.0101 | 0.0526 | 0.0452 | 0.0989 | 0.0755 | 0.0730 | 0.0660 | 0.1124 | 0.0959 | 0.6447 | 0.7039 | 0.0012 | 0.0020 | 0.0031 | 0.0065 | 0.0092 | 0.0131 | 0.0290 | 0.0361 | 0.0788 | 0.0934 | 0.1280 | 0.1326 | 0.0965 | 0.1068 | 0.1320 | 0.1384 | 0.5220 | 0.4711 | 0.0005 | 0.0012 | 0.0038 | 0.0208 | 0.0676 | 0.1100 | 0.0939 | 0.1245 | 0.5777 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 666 | 790 | | 3561 | 6069 | 315.0 | 63.10 | 119.80 | 156.57 | 227 | 261 | 284 | 299 | 314 | 331 | 348 | 367 | 395 | 0.1005 | 610 | 0.944 | 100.02 | 29.00 | 1 | 0.0702 | 250 | 0.0018 | 20.47 | 6.604 | 0.2773 | 103228.0 | 35100000 | 12300000000 | 4460000000000 | 0.4022 | 0.2404 | 0.0004 | 0.0003 | 0.0000 | 0.0003 | 0.0021 | 0.0003 | 0.0141 | 0.0006 | 0.0428 | 0.0204 | 0.0782 | 0.0351 | 0.0669 | 0.0260 | 0.0973 | 0.0348 | 0.6981 | 0.8823 | 0.0003 | 0.0003 | 0.0000 | 0.0003 | 0.0007 | 0.0003 | 0.0034 | 0.0003 | 0.0180 | 0.0162 | 0.0312 | 0.0272 | 0.0220 | 0.0139 | 0.0339 | 0.0210 | 0.8904 | 0.9206 | 0.0055 | 0.0000 | 0.0092 | 0.0000 | 0.0295 | 0.0000 | 0.0368 | 0.0000 | 0.0976 | 0.0000 | 0.1860 | 0.0000 | 0.0994 | 0.0000 | 0.1400 | 0.0000 | 0.3959 | 0.0000 | 0.0006 | 0.0011 | 0.0034 | 0.0169 | 0.0410 | 0.0713 | 0.0691 | 0.0871 | 0.7096 | 20 | 26 | 33 | 40 | 50 | 72 | 111 | 174 | 336 | 0.0366 | 13.58 | 4.709 | 0.5959 | 38861.2 | 20100000 | 13000000000 | 9720000000000 | 0.4035 | 0.2191 | 0.0130 | 0.0025 | 0.0681 | 0.0076 | 0.1426 | 0.0245 | 0.1313 | 0.0700 | 0.1361 | 0.1308 | 0.1669 | 0.1975 | 0.1070 | 0.1156 | 0.1216 | 0.1089 | 0.1135 | 0.3426 | 0.0000 | 0.0008 | 0.0005 | 0.0004 | 0.0044 | 0.0012 | 0.0112 | 0.0082 | 0.0486 | 0.0434 | 0.0816 | 0.0643 | 0.0505 | 0.0549 | 0.0802 | 0.0680 | 0.7230 | 0.7588 | 0.0007 | 0.0008 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0160 | 0.0159 | 0.0625 | 0.0700 | 0.1006 | 0.1026 | 0.0569 | 0.0644 | 0.0944 | 0.0907 | 0.6655 | 0.6547 | 0.0000 | 0.0035 | 0.0047 | 0.0135 | 0.0541 | 0.0858 | 0.0553 | 0.0829 | 0.7002 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1202 | 629 | | 3328 | 8418 | 107.3 | 34.23 | 123.15 | 94.86 | 68 | 80 | 88 | 96 | 104 | 112 | 122 | 135 | 151 | 0.0986 | 830 | 0.231 | 169.10 | 42.20 | 3 | 0.2897 | 964 | 0.0010 | 62.39 | 7.144 | 0.1516 | 12681.7 | 1630000 | 227000000 | 34000000000 | 0.4848 | 0.1833 | 0.0006 | 0.0000 | 0.0062 | 0.0004 | 0.0296 | 0.0037 | 0.0889 | 0.0116 | 0.1705 | 0.0511 | 0.2341 | 0.1335 | 0.1692 | 0.1051 | 0.1316 | 0.1491 | 0.1692 | 0.5455 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0016 | 0.0003 | 0.0213 | 0.0046 | 0.0585 | 0.0354 | 0.1101 | 0.0827 | 0.0876 | 0.0423 | 0.1146 | 0.0813 | 0.6052 | 0.7534 | 0.0036 | 0.0109 | 0.0024 | 0.0163 | 0.0182 | 0.0245 | 0.0812 | 0.1226 | 0.1818 | 0.2670 | 0.1782 | 0.1853 | 0.1224 | 0.0981 | 0.1479 | 0.1390 | 0.2642 | 0.1362 | 0.0006 | 0.0006 | 0.0077 | 0.0379 | 0.1247 | 0.1433 | 0.1093 | 0.1549 | 0.4210 | 27 | 47 | 62 | 77 | 96 | 120 | 152 | 193 | 257 | 0.0090 | 14.86 | 5.556 | 0.4071 | 24163.0 | 6350000 | 2030000000 | 746000000000 | 0.5797 | 0.1151 | 0.0304 | 0.0016 | 0.1306 | 0.0066 | 0.2172 | 0.0487 | 0.1928 | 0.1050 | 0.1637 | 0.1644 | 0.1333 | 0.2011 | 0.0683 | 0.1502 | 0.0501 | 0.1416 | 0.0135 | 0.1808 | 0.0005 | 0.0008 | 0.0036 | 0.0010 | 0.0061 | 0.0053 | 0.0229 | 0.0187 | 0.0800 | 0.0542 | 0.1217 | 0.0941 | 0.1144 | 0.0875 | 0.1389 | 0.1205 | 0.5119 | 0.6179 | 0.0011 | 0.0034 | 0.0053 | 0.0116 | 0.0167 | 0.0198 | 0.0456 | 0.0545 | 0.1094 | 0.1369 | 0.1759 | 0.1803 | 0.1265 | 0.1345 | 0.1527 | 0.1572 | 0.3666 | 0.3018 | 0.0012 | 0.0055 | 0.0092 | 0.0348 | 0.0944 | 0.1521 | 0.1225 | 0.1512 | 0.4291 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 317 | 690 | | 3464 | 11834 | 342.0 | 75.63 | 178.33 | 204.51 | 250 | 275 | 296 | 316 | 334 | 353 | 374 | 407 | 449 | 0.0724 | 857 | 0.954 | 122.41 | 43.14 | 1 | 0.0944 | 327 | 0.0010 | 39.91 | 7.112 | 0.1793 | 122696.0 | 46100000 | 18100000000 | 7380000000000 | 0.3949 | 0.2434 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0033 | 0.0000 | 0.0135 | 0.0025 | 0.0652 | 0.0246 | 0.1226 | 0.0467 | 0.1086 | 0.0418 | 0.1407 | 0.0563 | 0.5461 | 0.8278 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0061 | 0.0015 | 0.0275 | 0.0178 | 0.0582 | 0.0338 | 0.0453 | 0.0228 | 0.0735 | 0.0336 | 0.7874 | 0.8906 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0061 | 0.0000 | 0.0350 | 0.0000 | 0.1035 | 0.0000 | 0.1461 | 0.0000 | 0.0989 | 0.0000 | 0.1370 | 0.0000 | 0.4718 | 0.0000 | 0.0006 | 0.0025 | 0.0063 | 0.0151 | 0.0753 | 0.0834 | 0.0997 | 0.1173 | 0.5997 | 15 | 19 | 31 | 55 | 87 | 145 | 230 | 323 | 470 | 0.0227 | 19.50 | 5.564 | 0.4886 | 73621.5 | 41900000 | 28500000000 | 21900000000000 | 0.6117 | 0.0866 | 0.0329 | 0.0009 | 0.1078 | 0.0038 | 0.2187 | 0.0509 | 0.1920 | 0.0937 | 0.1694 | 0.1715 | 0.1283 | 0.2068 | 0.0688 | 0.1413 | 0.0431 | 0.1328 | 0.0390 | 0.1983 | 0.0002 | 0.0002 | 0.0004 | 0.0002 | 0.0017 | 0.0009 | 0.0090 | 0.0061 | 0.0363 | 0.0348 | 0.0722 | 0.0563 | 0.0539 | 0.0445 | 0.0705 | 0.0661 | 0.7557 | 0.7909 | 0.0003 | 0.0006 | 0.0018 | 0.0012 | 0.0021 | 0.0033 | 0.0127 | 0.0169 | 0.0496 | 0.0586 | 0.0939 | 0.1112 | 0.0702 | 0.0843 | 0.0915 | 0.0991 | 0.6779 | 0.6248 | 0.0000 | 0.0007 | 0.0017 | 0.0106 | 0.0439 | 0.0866 | 0.0599 | 0.0792 | 0.7175 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 873 | 826 | | 3064 | 6137 | 665.1 | 116.47 | 15.42 | 8.04 | 492 | 567 | 616 | 649 | 680 | 707 | 733 | 763 | 800 | 0.0893 | 548 | 0.993 | 122.00 | 37.22 | 1 | 0.0979 | 300 | 0.0008 | 64.26 | 7.305 | 0.1764 | 455869.0 | 321000000 | 230000000000 | 169000000000000 | 0.4008 | 0.2360 | 0.0000 | 0.0000 | 0.0004 | 0.0003 | 0.0026 | 0.0000 | 0.0061 | 0.0010 | 0.0299 | 0.0170 | 0.0464 | 0.0304 | 0.0438 | 0.0180 | 0.0520 | 0.0277 | 0.8189 | 0.9056 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0010 | 0.0186 | 0.0166 | 0.0266 | 0.0282 | 0.0190 | 0.0159 | 0.0274 | 0.0239 | 0.9060 | 0.9143 | 0.0000 | 0.0000 | 0.0063 | 0.0000 | 0.0031 | 0.0000 | 0.0563 | 0.0000 | 0.0875 | 0.0000 | 0.1125 | 0.0000 | 0.0906 | 0.0000 | 0.1125 | 0.0000 | 0.5313 | 0.0000 | 0.0006 | 0.0053 | 0.0029 | 0.0135 | 0.0224 | 0.0494 | 0.0371 | 0.0530 | 0.8158 | 9 | 10 | 11 | 12 | 13 | 15 | 16 | 19 | 25 | 0.3326 | 0.28 | 1.109 | 0.7287 | 302.3 | 7707.87 | 246475 | 9230000 | 0.5740 | 0.1078 | 0.0370 | 0.0041 | 0.0648 | 0.0041 | 0.1039 | 0.0126 | 0.1337 | 0.0236 | 0.1566 | 0.0577 | 0.1880 | 0.1004 | 0.1606 | 0.1497 | 0.1151 | 0.2427 | 0.0403 | 0.4050 | 0.0184 | 0.0004 | 0.0317 | 0.0011 | 0.0455 | 0.0041 | 0.0608 | 0.0114 | 0.0782 | 0.0408 | 0.0945 | 0.0788 | 0.0862 | 0.1063 | 0.1277 | 0.1658 | 0.4570 | 0.5914 | 0.0395 | 0.0410 | 0.0482 | 0.0420 | 0.0556 | 0.0400 | 0.0649 | 0.0470 | 0.0803 | 0.0561 | 0.0770 | 0.0681 | 0.0663 | 0.0681 | 0.1071 | 0.1692 | 0.4612 | 0.4685 | 0.0423 | 0.0379 | 0.0347 | 0.0520 | 0.0863 | 0.1089 | 0.1044 | 0.1262 | 0.4073 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1044 | 317 | | 12277 | 27737 | 337.8 | 80.82 | 126.25 | 196.68 | 245 | 268 | 287 | 306 | 326 | 349 | 374 | 406 | 447 | 0.0408 | 1133 | 1.055 | 137.89 | 53.26 | 1 | 0.0307 | 377 | 0.0011 | 31.32 | 7.089 | 0.2146 | 120627.0 | 45500000 | 18100000000 | 7610000000000 | 0.4436 | 0.2108 | 0.0003 | 0.0000 | 0.0014 | 0.0000 | 0.0075 | 0.0005 | 0.0193 | 0.0028 | 0.0768 | 0.0156 | 0.1399 | 0.0382 | 0.1395 | 0.0401 | 0.1655 | 0.0606 | 0.4499 | 0.8421 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0066 | 0.0003 | 0.0331 | 0.0088 | 0.0616 | 0.0201 | 0.0593 | 0.0159 | 0.0849 | 0.0256 | 0.7518 | 0.9293 | 0.0008 | 0.0082 | 0.0036 | 0.0192 | 0.0097 | 0.0549 | 0.0449 | 0.1152 | 0.1237 | 0.1578 | 0.1556 | 0.1852 | 0.1144 | 0.1221 | 0.1516 | 0.1221 | 0.3957 | 0.2154 | 0.0007 | 0.0024 | 0.0049 | 0.0284 | 0.0649 | 0.1105 | 0.0822 | 0.1107 | 0.5952 | 5 | 7 | 8 | 10 | 13 | 46 | 142 | 252 | 404 | 0.0900 | 13.02 | 4.139 | 0.4903 | 54618.6 | 33500000 | 26000000000 | 23800000000000 | 0.3964 | 0.2554 | 0.0519 | 0.0030 | 0.2024 | 0.0144 | 0.3281 | 0.0926 | 0.1490 | 0.1590 | 0.1211 | 0.2328 | 0.0760 | 0.2176 | 0.0384 | 0.1206 | 0.0256 | 0.0893 | 0.0075 | 0.0708 | 0.0000 | 0.0000 | 0.0002 | 0.0003 | 0.0009 | 0.0006 | 0.0045 | 0.0028 | 0.0333 | 0.0259 | 0.0610 | 0.0514 | 0.0479 | 0.0383 | 0.0731 | 0.0617 | 0.7792 | 0.8190 | 0.0002 | 0.0001 | 0.0001 | 0.0012 | 0.0011 | 0.0016 | 0.0074 | 0.0108 | 0.0452 | 0.0500 | 0.0802 | 0.0994 | 0.0683 | 0.0688 | 0.0954 | 0.1041 | 0.7019 | 0.6639 | 0.0001 | 0.0001 | 0.0005 | 0.0061 | 0.0373 | 0.0712 | 0.0564 | 0.0847 | 0.7437 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1078 | 523 | | 14942 | 30535 | 213.6 | 65.41 | 182.99 | 225.98 | 137 | 159 | 176 | 193 | 208 | 224 | 242 | 265 | 299 | 0.0495 | 1511 | 0.501 | 139.13 | 33.29 | 9 | 0.0285 | 426 | 0.0011 | 32.46 | 7.146 | 0.2116 | 49882.5 | 12600000 | 3430000000 | 996000000000 | 0.4707 | 0.1872 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0114 | 0.0010 | 0.0396 | 0.0054 | 0.1050 | 0.0284 | 0.1755 | 0.0659 | 0.1723 | 0.0644 | 0.1742 | 0.0921 | 0.3187 | 0.7427 | 0.0005 | 0.0000 | 0.0007 | 0.0001 | 0.0015 | 0.0002 | 0.0105 | 0.0022 | 0.0389 | 0.0148 | 0.0680 | 0.0352 | 0.0666 | 0.0291 | 0.0852 | 0.0452 | 0.7281 | 0.8731 | 0.0023 | 0.0054 | 0.0057 | 0.0075 | 0.0154 | 0.0299 | 0.0570 | 0.0680 | 0.1115 | 0.1497 | 0.1591 | 0.1844 | 0.1081 | 0.1163 | 0.1420 | 0.1306 | 0.3989 | 0.3082 | 0.0007 | 0.0032 | 0.0068 | 0.0241 | 0.0727 | 0.1106 | 0.0894 | 0.1272 | 0.5653 | 7 | 9 | 13 | 25 | 64 | 146 | 254 | 375 | 525 | 0.0542 | 24.53 | 5.282 | 0.4416 | 84546.7 | 50200000 | 34700000000 | 26800000000000 | 0.4917 | 0.1628 | 0.0917 | 0.0009 | 0.2762 | 0.0235 | 0.3457 | 0.2055 | 0.1342 | 0.1964 | 0.0753 | 0.2196 | 0.0473 | 0.1648 | 0.0208 | 0.0975 | 0.0068 | 0.0592 | 0.0019 | 0.0325 | 0.0001 | 0.0000 | 0.0004 | 0.0004 | 0.0005 | 0.0007 | 0.0084 | 0.0060 | 0.0544 | 0.0468 | 0.0935 | 0.0840 | 0.0596 | 0.0515 | 0.0953 | 0.0815 | 0.6877 | 0.7291 | 0.0001 | 0.0001 | 0.0001 | 0.0004 | 0.0013 | 0.0016 | 0.0121 | 0.0199 | 0.0750 | 0.0811 | 0.1193 | 0.1295 | 0.0741 | 0.0859 | 0.1155 | 0.1244 | 0.6026 | 0.5571 | 0.0002 | 0.0002 | 0.0006 | 0.0101 | 0.0639 | 0.1058 | 0.0698 | 0.1080 | 0.6414 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 659 | 414 | | 3454 | 6251 | 174.4 | 39.87 | 242.89 | 154.32 | 131 | 143 | 152 | 159 | 167 | 177 | 189 | 204 | 226 | 0.1125 | 703 | 1.107 | 91.24 | 26.63 | 1 | 0.0617 | 213 | 0.0019 | 25.62 | 6.561 | 0.2385 | 32018.5 | 6210000 | 1280000000 | 278000000000 | 0.4520 | 0.2052 | 0.0004 | 0.0000 | 0.0009 | 0.0003 | 0.0088 | 0.0006 | 0.0206 | 0.0022 | 0.0697 | 0.0235 | 0.1434 | 0.0423 | 0.1298 | 0.0346 | 0.1684 | 0.0676 | 0.4579 | 0.8289 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0003 | 0.0052 | 0.0003 | 0.0351 | 0.0160 | 0.0762 | 0.0274 | 0.0616 | 0.0189 | 0.1043 | 0.0335 | 0.7155 | 0.9036 | 0.0017 | 0.0154 | 0.0134 | 0.0205 | 0.0185 | 0.0308 | 0.0487 | 0.1026 | 0.1546 | 0.1231 | 0.1748 | 0.1846 | 0.1294 | 0.1538 | 0.1429 | 0.0923 | 0.3160 | 0.2769 | 0.0007 | 0.0033 | 0.0080 | 0.0361 | 0.0916 | 0.1424 | 0.0989 | 0.1404 | 0.4786 | 79 | 111 | 142 | 170 | 206 | 251 | 299 | 360 | 457 | 0.0013 | 68.96 | 7.135 | 0.2323 | 82803.2 | 35900000 | 18500000000 | 10900000000000 | 0.5283 | 0.1292 | 0.0088 | 0.0007 | 0.0739 | 0.0045 | 0.1684 | 0.0182 | 0.1611 | 0.0636 | 0.1859 | 0.1374 | 0.1720 | 0.2049 | 0.1061 | 0.1528 | 0.0820 | 0.1545 | 0.0417 | 0.2633 | 0.0003 | 0.0002 | 0.0027 | 0.0005 | 0.0066 | 0.0040 | 0.0217 | 0.0160 | 0.0714 | 0.0488 | 0.1042 | 0.0905 | 0.0819 | 0.0726 | 0.1153 | 0.1014 | 0.5959 | 0.6660 | 0.0041 | 0.0042 | 0.0051 | 0.0035 | 0.0128 | 0.0229 | 0.0389 | 0.0660 | 0.1064 | 0.1313 | 0.1529 | 0.1771 | 0.1233 | 0.1188 | 0.1483 | 0.1465 | 0.4082 | 0.3299 | 0.0004 | 0.0031 | 0.0100 | 0.0268 | 0.0824 | 0.1234 | 0.1031 | 0.1388 | 0.5121 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 121 | 590 | | 6826 | 22797 | 692.3 | 141.16 | 184.25 | 147.65 | 524 | 569 | 603 | 636 | 672 | 711 | 754 | 812 | 894 | 0.0504 | 1149 | 1.195 | 96.01 | 36.50 | 1 | 0.0355 | 242 | 0.0006 | 74.81 | 7.679 | 0.1333 | 499160.0 | 375000000 | 293000000000 | 238000000000000 | 0.4097 | 0.2333 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0033 | 0.0000 | 0.0134 | 0.0015 | 0.0541 | 0.0141 | 0.1179 | 0.0327 | 0.1221 | 0.0242 | 0.1447 | 0.0447 | 0.5439 | 0.8825 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0054 | 0.0001 | 0.0244 | 0.0100 | 0.0560 | 0.0208 | 0.0529 | 0.0091 | 0.0796 | 0.0171 | 0.7802 | 0.9428 | 0.0000 | 0.0210 | 0.0059 | 0.0385 | 0.0245 | 0.0559 | 0.0422 | 0.0594 | 0.1114 | 0.1713 | 0.1401 | 0.1608 | 0.1241 | 0.1014 | 0.1595 | 0.1399 | 0.3924 | 0.2517 | 0.0007 | 0.0033 | 0.0052 | 0.0244 | 0.0711 | 0.1157 | 0.0949 | 0.1252 | 0.5596 | 31 | 53 | 80 | 111 | 147 | 188 | 236 | 298 | 396 | 0.0053 | 17.90 | 6.140 | 0.3553 | 55747.2 | 22400000 | 11300000000 | 7040000000000 | 0.4802 | 0.1654 | 0.0189 | 0.0009 | 0.1045 | 0.0065 | 0.1943 | 0.0481 | 0.1712 | 0.0929 | 0.1772 | 0.1570 | 0.1568 | 0.1982 | 0.0804 | 0.1530 | 0.0592 | 0.1463 | 0.0375 | 0.1971 | 0.0006 | 0.0003 | 0.0018 | 0.0010 | 0.0062 | 0.0037 | 0.0214 | 0.0144 | 0.0636 | 0.0533 | 0.1041 | 0.0946 | 0.0826 | 0.0723 | 0.1081 | 0.1001 | 0.6117 | 0.6604 | 0.0021 | 0.0022 | 0.0055 | 0.0077 | 0.0141 | 0.0176 | 0.0366 | 0.0471 | 0.0854 | 0.0843 | 0.1155 | 0.1211 | 0.0905 | 0.0961 | 0.1101 | 0.1108 | 0.5402 | 0.5131 | 0.0011 | 0.0033 | 0.0088 | 0.0271 | 0.0757 | 0.1130 | 0.0967 | 0.1074 | 0.5670 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1107 | 725 | | 3073 | 3969 | 338.0 | 79.28 | 111.41 | 132.27 | 234 | 267 | 290 | 314 | 335 | 356 | 378 | 405 | 441 | 0.1217 | 483 | 1.226 | 141.20 | 63.63 | 1 | 0.1276 | 392 | 0.0012 | 36.06 | 6.918 | 0.1908 | 120541.0 | 45200000 | 17700000000 | 7230000000000 | 0.4322 | 0.2106 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0044 | 0.0000 | 0.0183 | 0.0046 | 0.0759 | 0.0201 | 0.1506 | 0.0466 | 0.1440 | 0.0508 | 0.1849 | 0.0756 | 0.4219 | 0.8019 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0017 | 0.0000 | 0.0079 | 0.0033 | 0.0277 | 0.0147 | 0.0513 | 0.0287 | 0.0484 | 0.0184 | 0.0778 | 0.0277 | 0.7854 | 0.9068 | 0.0033 | 0.0248 | 0.0082 | 0.0124 | 0.0131 | 0.0559 | 0.0784 | 0.1801 | 0.1373 | 0.2236 | 0.2124 | 0.1677 | 0.1193 | 0.1242 | 0.1373 | 0.1118 | 0.2909 | 0.0994 | 0.0007 | 0.0013 | 0.0060 | 0.0219 | 0.0672 | 0.1203 | 0.1110 | 0.1356 | 0.5359 | 12 | 23 | 35 | 48 | 64 | 85 | 116 | 178 | 274 | 0.0254 | 11.05 | 4.985 | 0.5393 | 29902.0 | 13200000 | 7610000000 | 5130000000000 | 0.5025 | 0.1307 | 0.0142 | 0.0010 | 0.0548 | 0.0120 | 0.1258 | 0.0239 | 0.1400 | 0.0658 | 0.1826 | 0.1396 | 0.1562 | 0.1854 | 0.1014 | 0.1206 | 0.1055 | 0.1356 | 0.1197 | 0.3161 | 0.0006 | 0.0000 | 0.0000 | 0.0026 | 0.0019 | 0.0036 | 0.0130 | 0.0104 | 0.0467 | 0.0410 | 0.0746 | 0.0607 | 0.0655 | 0.0524 | 0.0966 | 0.0841 | 0.7010 | 0.7451 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0038 | 0.0043 | 0.0076 | 0.0152 | 0.0725 | 0.0769 | 0.0925 | 0.1073 | 0.0620 | 0.0921 | 0.1115 | 0.1138 | 0.6501 | 0.5894 | 0.0024 | 0.0016 | 0.0041 | 0.0114 | 0.0571 | 0.0702 | 0.0637 | 0.0980 | 0.6914 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 445 | 885 | | 6720 | 10576 | 145.0 | 36.97 | 295.37 | 234.47 | 104 | 115 | 123 | 131 | 139 | 148 | 158 | 172 | 194 | 0.1029 | 1088 | 0.626 | 198.72 | 50.01 | 1 | 0.0999 | 671 | 0.0017 | 31.55 | 6.712 | 0.2250 | 22380.3 | 3690000 | 653000000 | 124000000000 | 0.4622 | 0.1938 | 0.0005 | 0.0000 | 0.0030 | 0.0002 | 0.0103 | 0.0013 | 0.0323 | 0.0038 | 0.0867 | 0.0230 | 0.1608 | 0.0551 | 0.1817 | 0.0633 | 0.1822 | 0.0935 | 0.3425 | 0.7598 | 0.0004 | 0.0000 | 0.0019 | 0.0002 | 0.0023 | 0.0009 | 0.0120 | 0.0021 | 0.0362 | 0.0137 | 0.0734 | 0.0334 | 0.0766 | 0.0241 | 0.1038 | 0.0442 | 0.6935 | 0.8815 | 0.0071 | 0.0081 | 0.0063 | 0.0444 | 0.0205 | 0.0282 | 0.0947 | 0.1290 | 0.1539 | 0.1673 | 0.1902 | 0.1714 | 0.1200 | 0.0968 | 0.1350 | 0.1310 | 0.2723 | 0.2238 | 0.0007 | 0.0044 | 0.0119 | 0.0408 | 0.0983 | 0.1353 | 0.1272 | 0.1452 | 0.4362 | 37 | 76 | 126 | 181 | 247 | 316 | 392 | 484 | 624 | 0.0023 | 85.50 | 7.315 | 0.2151 | 142212.0 | 87400000 | 63000000000 | 51000000000000 | 0.5432 | 0.1364 | 0.0279 | 0.0023 | 0.1381 | 0.0113 | 0.2587 | 0.0476 | 0.1904 | 0.1232 | 0.1774 | 0.1886 | 0.1211 | 0.2083 | 0.0551 | 0.1398 | 0.0244 | 0.1359 | 0.0068 | 0.1429 | 0.0004 | 0.0002 | 0.0022 | 0.0026 | 0.0044 | 0.0034 | 0.0196 | 0.0138 | 0.0714 | 0.0585 | 0.1250 | 0.1079 | 0.1052 | 0.0792 | 0.1248 | 0.1135 | 0.5471 | 0.6207 | 0.0022 | 0.0031 | 0.0054 | 0.0083 | 0.0165 | 0.0211 | 0.0326 | 0.0418 | 0.0979 | 0.1017 | 0.1600 | 0.1663 | 0.1128 | 0.1228 | 0.1279 | 0.1459 | 0.4447 | 0.3890 | 0.0009 | 0.0046 | 0.0110 | 0.0265 | 0.0867 | 0.1423 | 0.1125 | 0.1244 | 0.4912 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 338 | 385 | | 6192 | 19742 | 233.9 | 53.78 | 137.63 | 180.46 | 171 | 188 | 203 | 216 | 228 | 242 | 256 | 273 | 303 | 0.0555 | 1095 | 1.184 | 93.43 | 33.02 | 1 | 0.0363 | 225 | 0.0009 | 46.43 | 7.247 | 0.1652 | 57591.1 | 14900000 | 4100000000 | 1190000000000 | 0.3895 | 0.2646 | 0.0000 | 0.0000 | 0.0018 | 0.0002 | 0.0041 | 0.0002 | 0.0216 | 0.0019 | 0.0685 | 0.0188 | 0.1277 | 0.0445 | 0.1508 | 0.0419 | 0.1815 | 0.0664 | 0.4442 | 0.8263 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0002 | 0.0094 | 0.0011 | 0.0292 | 0.0133 | 0.0619 | 0.0277 | 0.0581 | 0.0198 | 0.0873 | 0.0284 | 0.7507 | 0.9093 | 0.0076 | 0.0147 | 0.0066 | 0.0265 | 0.0199 | 0.0265 | 0.0939 | 0.1088 | 0.1319 | 0.1559 | 0.1717 | 0.1706 | 0.1063 | 0.0971 | 0.1395 | 0.1294 | 0.3226 | 0.2706 | 0.0007 | 0.0025 | 0.0074 | 0.0298 | 0.0895 | 0.1288 | 0.1057 | 0.1541 | 0.4816 | 12 | 14 | 17 | 23 | 43 | 88 | 167 | 264 | 387 | 0.0461 | 28.23 | 5.244 | 0.4903 | 51505.6 | 27300000 | 17700000000 | 13300000000000 | 0.5436 | 0.1197 | 0.0589 | 0.0037 | 0.2135 | 0.0134 | 0.3305 | 0.1158 | 0.1622 | 0.1818 | 0.0910 | 0.2308 | 0.0773 | 0.1922 | 0.0344 | 0.1091 | 0.0245 | 0.0820 | 0.0077 | 0.0712 | 0.0000 | 0.0004 | 0.0004 | 0.0007 | 0.0018 | 0.0016 | 0.0103 | 0.0074 | 0.0488 | 0.0426 | 0.0827 | 0.0744 | 0.0564 | 0.0488 | 0.0887 | 0.0770 | 0.7108 | 0.7471 | 0.0003 | 0.0002 | 0.0010 | 0.0013 | 0.0015 | 0.0013 | 0.0126 | 0.0158 | 0.0614 | 0.0710 | 0.1023 | 0.1142 | 0.0737 | 0.0805 | 0.1031 | 0.1182 | 0.6440 | 0.5975 | 0.0002 | 0.0003 | 0.0017 | 0.0124 | 0.0554 | 0.0907 | 0.0685 | 0.0965 | 0.6744 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 156 | 594 | | 9080 | 15618 | 311.0 | 68.29 | 98.46 | 121.64 | 229 | 251 | 270 | 288 | 305 | 324 | 344 | 367 | 401 | 0.0788 | 1231 | 0.960 | 135.72 | 35.01 | 1 | 0.0352 | 320 | 0.0013 | 28.86 | 6.929 | 0.2122 | 101409.0 | 34600000 | 12300000000 | 4590000000000 | 0.4537 | 0.2035 | 0.0010 | 0.0000 | 0.0019 | 0.0001 | 0.0068 | 0.0009 | 0.0222 | 0.0025 | 0.0705 | 0.0167 | 0.1362 | 0.0410 | 0.1452 | 0.0416 | 0.1613 | 0.0640 | 0.4548 | 0.8331 | 0.0007 | 0.0000 | 0.0005 | 0.0000 | 0.0027 | 0.0006 | 0.0099 | 0.0020 | 0.0293 | 0.0115 | 0.0662 | 0.0283 | 0.0633 | 0.0223 | 0.0823 | 0.0364 | 0.7452 | 0.8989 | 0.0056 | 0.0027 | 0.0124 | 0.0318 | 0.0204 | 0.0637 | 0.0667 | 0.1141 | 0.1248 | 0.2042 | 0.1513 | 0.1485 | 0.1328 | 0.0716 | 0.1575 | 0.1300 | 0.3286 | 0.2334 | 0.0007 | 0.0030 | 0.0096 | 0.0287 | 0.0674 | 0.1168 | 0.1070 | 0.1261 | 0.5408 | 12 | 14 | 17 | 23 | 41 | 74 | 118 | 173 | 260 | 0.0390 | 25.52 | 5.297 | 0.4490 | 24490.2 | 9030000 | 4150000000 | 2200000000000 | 0.5460 | 0.1292 | 0.0690 | 0.0018 | 0.1999 | 0.0187 | 0.2994 | 0.1257 | 0.1613 | 0.1617 | 0.1323 | 0.2185 | 0.0814 | 0.1892 | 0.0378 | 0.1186 | 0.0145 | 0.0981 | 0.0044 | 0.0678 | 0.0002 | 0.0003 | 0.0012 | 0.0006 | 0.0031 | 0.0027 | 0.0151 | 0.0124 | 0.0691 | 0.0593 | 0.1090 | 0.0934 | 0.0785 | 0.0690 | 0.1141 | 0.1000 | 0.6096 | 0.6622 | 0.0011 | 0.0015 | 0.0023 | 0.0025 | 0.0079 | 0.0093 | 0.0234 | 0.0284 | 0.0888 | 0.0944 | 0.1239 | 0.1444 | 0.0960 | 0.0946 | 0.1298 | 0.1284 | 0.5268 | 0.4966 | 0.0002 | 0.0022 | 0.0039 | 0.0202 | 0.0788 | 0.1208 | 0.0884 | 0.1238 | 0.5618 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 260 | 906 | | 6741 | 5810 | 457.5 | 85.03 | 189.24 | 346.87 | 354 | 397 | 434 | 457 | 471 | 484 | 497 | 515 | 542 | 0.1139 | 662 | 0.726 | 107.34 | 27.78 | 4 | 0.0481 | 324 | 0.0013 | 28.66 | 7.062 | 0.2336 | 216541.0 | 105000000 | 52100000000 | 26300000000000 | 0.4404 | 0.2127 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0038 | 0.0000 | 0.0072 | 0.0011 | 0.0244 | 0.0142 | 0.0415 | 0.0371 | 0.0385 | 0.0169 | 0.0651 | 0.0290 | 0.8182 | 0.9017 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0026 | 0.0000 | 0.0044 | 0.0005 | 0.0175 | 0.0138 | 0.0303 | 0.0338 | 0.0218 | 0.0135 | 0.0322 | 0.0208 | 0.8903 | 0.9176 | 0.0174 | 0.0000 | 0.0209 | 0.0000 | 0.0192 | 0.0000 | 0.0314 | 0.0000 | 0.0401 | 0.0000 | 0.0627 | 0.0000 | 0.0592 | 0.0000 | 0.0941 | 0.0000 | 0.6551 | 0.0000 | 0.0007 | 0.0045 | 0.0057 | 0.0172 | 0.0314 | 0.0528 | 0.0617 | 0.0889 | 0.7372 | 15 | 17 | 18 | 21 | 27 | 55 | 114 | 280 | 602 | 0.2435 | 18.42 | 3.549 | 0.6966 | 156109.0 | 197000000 | 310000000000 | 567000000000000 | 0.6374 | 0.0658 | 0.0763 | 0.0000 | 0.1968 | 0.0329 | 0.2129 | 0.1024 | 0.1566 | 0.1225 | 0.1406 | 0.1846 | 0.1245 | 0.1554 | 0.0482 | 0.1280 | 0.0361 | 0.1188 | 0.0080 | 0.1554 | 0.0013 | 0.0000 | 0.0019 | 0.0006 | 0.0039 | 0.0023 | 0.0142 | 0.0138 | 0.0685 | 0.0619 | 0.0931 | 0.0865 | 0.0672 | 0.0613 | 0.1002 | 0.0980 | 0.6496 | 0.6756 | 0.0008 | 0.0000 | 0.0031 | 0.0025 | 0.0046 | 0.0067 | 0.0208 | 0.0200 | 0.0701 | 0.0835 | 0.1017 | 0.0943 | 0.0770 | 0.0760 | 0.1063 | 0.1077 | 0.6156 | 0.6093 | 0.0000 | 0.0014 | 0.0043 | 0.0157 | 0.0686 | 0.1029 | 0.0657 | 0.1064 | 0.6350 |