High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 842 | 577 | | 8312 | 37624 | 297.8 | 91.57 | 178.27 | 259.96 | 160 | 206 | 245 | 278 | 307 | 333 | 362 | 387 | 411 | 0.0319 | 1200 | 0.839 | 102.04 | 23.02 | 1 | 0.0298 | 248 | 0.0012 | 10.68 | 6.901 | 0.3043 | 97039.9 | 33700000 | 12200000000 | 4600000000000 | 0.3862 | 0.2351 | 0.0012 | 0.0000 | 0.0021 | 0.0005 | 0.0039 | 0.0017 | 0.0170 | 0.0054 | 0.0499 | 0.0240 | 0.0762 | 0.0398 | 0.0810 | 0.0408 | 0.1043 | 0.0580 | 0.6643 | 0.8299 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0003 | 0.0001 | 0.0033 | 0.0020 | 0.0152 | 0.0128 | 0.0244 | 0.0202 | 0.0207 | 0.0155 | 0.0268 | 0.0229 | 0.9088 | 0.9263 | 0.0015 | 0.0106 | 0.0030 | 0.0151 | 0.0049 | 0.0408 | 0.0118 | 0.0711 | 0.0323 | 0.0968 | 0.0433 | 0.1452 | 0.0429 | 0.0953 | 0.0771 | 0.1589 | 0.7831 | 0.3661 | 0.0009 | 0.0016 | 0.0029 | 0.0068 | 0.0201 | 0.0316 | 0.0289 | 0.0382 | 0.8689 | 8 | 10 | 12 | 16 | 37 | 86 | 182 | 353 | 594 | 0.1248 | 17.36 | 4.816 | 0.6022 | 99357.5 | 73300000 | 62400000000 | 58600000000000 | 0.4227 | 0.2238 | 0.0264 | 0.0016 | 0.1059 | 0.0050 | 0.1959 | 0.0402 | 0.1696 | 0.0969 | 0.1979 | 0.1765 | 0.1462 | 0.2004 | 0.0726 | 0.1356 | 0.0497 | 0.1265 | 0.0358 | 0.2174 | 0.0000 | 0.0002 | 0.0005 | 0.0004 | 0.0018 | 0.0011 | 0.0067 | 0.0062 | 0.0389 | 0.0323 | 0.0555 | 0.0517 | 0.0427 | 0.0407 | 0.0604 | 0.0544 | 0.7937 | 0.8129 | 0.0002 | 0.0007 | 0.0011 | 0.0010 | 0.0034 | 0.0033 | 0.0119 | 0.0117 | 0.0387 | 0.0431 | 0.0656 | 0.0654 | 0.0477 | 0.0528 | 0.0658 | 0.0696 | 0.7657 | 0.7523 | 0.0000 | 0.0006 | 0.0016 | 0.0095 | 0.0399 | 0.0611 | 0.0434 | 0.0640 | 0.7799 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 376 | 815 | | 6277 | 23826 | 431.4 | 82.01 | 114.95 | 189.20 | 331 | 361 | 383 | 403 | 426 | 447 | 473 | 503 | 544 | 0.0434 | 1033 | 0.842 | 82.28 | 28.16 | 1 | 0.0394 | 247 | 0.0009 | 43.90 | 7.226 | 0.1745 | 192840.0 | 89200000 | 42600000000 | 20900000000000 | 0.4504 | 0.2050 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0030 | 0.0000 | 0.0159 | 0.0007 | 0.0597 | 0.0143 | 0.1101 | 0.0347 | 0.1238 | 0.0286 | 0.1574 | 0.0475 | 0.5295 | 0.8742 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0071 | 0.0000 | 0.0301 | 0.0117 | 0.0512 | 0.0268 | 0.0508 | 0.0136 | 0.0737 | 0.0265 | 0.7865 | 0.9214 | 0.0030 | 0.0329 | 0.0071 | 0.0197 | 0.0243 | 0.0526 | 0.0943 | 0.1645 | 0.1400 | 0.2368 | 0.1684 | 0.1711 | 0.1197 | 0.1184 | 0.1379 | 0.1184 | 0.3053 | 0.0855 | 0.0007 | 0.0023 | 0.0119 | 0.0250 | 0.0781 | 0.1153 | 0.0982 | 0.1255 | 0.5430 | 9 | 11 | 14 | 17 | 24 | 44 | 100 | 202 | 343 | 0.0536 | 32.28 | 4.983 | 0.5358 | 49009.5 | 35200000 | 34900000000 | 42600000000000 | 0.5156 | 0.1405 | 0.0766 | 0.0042 | 0.1959 | 0.0170 | 0.2844 | 0.1298 | 0.1485 | 0.1714 | 0.1248 | 0.1956 | 0.0821 | 0.1646 | 0.0450 | 0.0980 | 0.0269 | 0.1018 | 0.0158 | 0.1177 | 0.0000 | 0.0004 | 0.0003 | 0.0002 | 0.0023 | 0.0016 | 0.0088 | 0.0101 | 0.0504 | 0.0422 | 0.0802 | 0.0661 | 0.0538 | 0.0498 | 0.0854 | 0.0812 | 0.7189 | 0.7485 | 0.0003 | 0.0005 | 0.0008 | 0.0009 | 0.0041 | 0.0030 | 0.0112 | 0.0163 | 0.0573 | 0.0598 | 0.0870 | 0.0918 | 0.0671 | 0.0702 | 0.0950 | 0.1061 | 0.6771 | 0.6513 | 0.0006 | 0.0010 | 0.0016 | 0.0108 | 0.0544 | 0.0823 | 0.0603 | 0.0952 | 0.6936 | ||
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1104 | 606 | | 7792 | 17317 | 455.1 | 84.64 | 91.04 | 159.85 | 350 | 380 | 405 | 428 | 449 | 472 | 497 | 528 | 568 | 0.0587 | 1017 | 0.843 | 136.49 | 39.96 | 1 | 0.0508 | 396 | 0.0009 | 41.02 | 7.256 | 0.1774 | 214248.0 | 104000000 | 52400000000 | 27200000000000 | 0.4390 | 0.2040 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0136 | 0.0005 | 0.0498 | 0.0107 | 0.1097 | 0.0237 | 0.1108 | 0.0193 | 0.1486 | 0.0344 | 0.5627 | 0.9113 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0024 | 0.0000 | 0.0058 | 0.0004 | 0.0229 | 0.0095 | 0.0478 | 0.0189 | 0.0484 | 0.0112 | 0.0635 | 0.0227 | 0.8089 | 0.9373 | 0.0050 | 0.0153 | 0.0059 | 0.0153 | 0.0243 | 0.0458 | 0.0703 | 0.1756 | 0.1456 | 0.1221 | 0.1816 | 0.1603 | 0.1364 | 0.0916 | 0.1356 | 0.1069 | 0.2954 | 0.2672 | 0.0019 | 0.0038 | 0.0059 | 0.0261 | 0.0676 | 0.1051 | 0.0997 | 0.1070 | 0.5829 | 5 | 6 | 7 | 9 | 11 | 25 | 76 | 148 | 295 | 0.1599 | 22.17 | 4.036 | 0.5973 | 33837.1 | 18800000 | 12800000000 | 9900000000000 | 0.6360 | 0.0673 | 0.0357 | 0.0021 | 0.1417 | 0.0167 | 0.2200 | 0.0889 | 0.1536 | 0.1271 | 0.1497 | 0.1836 | 0.1249 | 0.1857 | 0.0694 | 0.1130 | 0.0565 | 0.1130 | 0.0486 | 0.1700 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0006 | 0.0003 | 0.0113 | 0.0062 | 0.0430 | 0.0382 | 0.0708 | 0.0689 | 0.0549 | 0.0430 | 0.0815 | 0.0753 | 0.7371 | 0.7679 | 0.0002 | 0.0000 | 0.0005 | 0.0010 | 0.0049 | 0.0052 | 0.0117 | 0.0160 | 0.0608 | 0.0640 | 0.0963 | 0.1006 | 0.0629 | 0.0694 | 0.0974 | 0.1091 | 0.6653 | 0.6349 | 0.0002 | 0.0006 | 0.0023 | 0.0121 | 0.0489 | 0.0886 | 0.0606 | 0.0917 | 0.6949 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 274 | 223 | | 6457 | 17021 | 77.3 | 19.26 | 210.94 | 213.95 | 57 | 61 | 66 | 70 | 74 | 78 | 84 | 91 | 103 | 0.0644 | 1096 | 0.843 | 90.43 | 26.17 | 1 | 0.0367 | 237 | 0.0028 | 17.12 | 6.228 | 0.2745 | 6348.3 | 556064 | 52200000 | 5250000000 | 0.4510 | 0.1996 | 0.0010 | 0.0000 | 0.0056 | 0.0003 | 0.0133 | 0.0005 | 0.0380 | 0.0061 | 0.0745 | 0.0225 | 0.1425 | 0.0484 | 0.1711 | 0.0522 | 0.2152 | 0.0849 | 0.3389 | 0.7851 | 0.0004 | 0.0000 | 0.0023 | 0.0002 | 0.0068 | 0.0000 | 0.0163 | 0.0020 | 0.0342 | 0.0138 | 0.0671 | 0.0273 | 0.0778 | 0.0218 | 0.1102 | 0.0414 | 0.6848 | 0.8935 | 0.0074 | 0.0130 | 0.0197 | 0.0216 | 0.0303 | 0.0670 | 0.0663 | 0.1058 | 0.1286 | 0.1685 | 0.1335 | 0.1598 | 0.1179 | 0.1102 | 0.1605 | 0.1102 | 0.3358 | 0.2441 | 0.0024 | 0.0094 | 0.0171 | 0.0447 | 0.0765 | 0.1024 | 0.1080 | 0.1279 | 0.5114 | 18 | 30 | 63 | 104 | 145 | 194 | 257 | 356 | 511 | 0.0108 | 28.47 | 6.188 | 0.3938 | 90266.1 | 55800000 | 45300000000 | 46700000000000 | 0.5019 | 0.1685 | 0.0158 | 0.0008 | 0.0801 | 0.0060 | 0.1780 | 0.0286 | 0.1711 | 0.0730 | 0.1885 | 0.1548 | 0.1561 | 0.2064 | 0.0991 | 0.1523 | 0.0752 | 0.1528 | 0.0360 | 0.2253 | 0.0009 | 0.0001 | 0.0013 | 0.0006 | 0.0042 | 0.0030 | 0.0144 | 0.0093 | 0.0568 | 0.0438 | 0.0954 | 0.0772 | 0.0796 | 0.0684 | 0.1057 | 0.0967 | 0.6416 | 0.7008 | 0.0013 | 0.0018 | 0.0031 | 0.0027 | 0.0098 | 0.0098 | 0.0233 | 0.0219 | 0.0729 | 0.0825 | 0.1141 | 0.1324 | 0.0873 | 0.0882 | 0.1187 | 0.1185 | 0.5694 | 0.5421 | 0.0022 | 0.0021 | 0.0062 | 0.0230 | 0.0643 | 0.1045 | 0.0826 | 0.1072 | 0.6079 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 305 | 753 | | 14531 | 31502 | 446.4 | 61.03 | 117.13 | 162.48 | 365 | 402 | 424 | 439 | 452 | 464 | 476 | 491 | 515 | 0.0488 | 1538 | 0.844 | 110.02 | 27.80 | 4 | 0.0189 | 274 | 0.0017 | 18.96 | 6.823 | 0.2707 | 202963.0 | 93800000 | 44000000000 | 21000000000000 | 0.4307 | 0.2135 | 0.0003 | 0.0001 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0036 | 0.0001 | 0.0149 | 0.0077 | 0.0284 | 0.0166 | 0.0253 | 0.0080 | 0.0383 | 0.0128 | 0.8882 | 0.9547 | 0.0001 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0001 | 0.0098 | 0.0077 | 0.0186 | 0.0166 | 0.0149 | 0.0080 | 0.0188 | 0.0117 | 0.9360 | 0.9558 | 0.0148 | 1.0000 | 0.0239 | 0.0000 | 0.0091 | 0.0000 | 0.0262 | 0.0000 | 0.0809 | 0.0000 | 0.0945 | 0.0000 | 0.0809 | 0.0000 | 0.1173 | 0.0000 | 0.5524 | 0.0000 | 0.0022 | 0.0070 | 0.0123 | 0.0187 | 0.0346 | 0.0523 | 0.0642 | 0.0921 | 0.7167 | 13 | 16 | 21 | 33 | 52 | 79 | 118 | 180 | 305 | 0.0400 | 19.55 | 4.937 | 0.5597 | 40119.5 | 22800000 | 16800000000 | 14600000000000 | 0.4801 | 0.1897 | 0.0180 | 0.0019 | 0.0684 | 0.0102 | 0.1417 | 0.0304 | 0.1389 | 0.0605 | 0.1660 | 0.1385 | 0.1648 | 0.1775 | 0.1107 | 0.1263 | 0.1041 | 0.1394 | 0.0873 | 0.3154 | 0.0012 | 0.0003 | 0.0022 | 0.0020 | 0.0034 | 0.0030 | 0.0115 | 0.0124 | 0.0463 | 0.0387 | 0.0745 | 0.0614 | 0.0495 | 0.0472 | 0.0766 | 0.0656 | 0.7348 | 0.7694 | 0.0005 | 0.0007 | 0.0024 | 0.0020 | 0.0066 | 0.0068 | 0.0187 | 0.0217 | 0.0585 | 0.0622 | 0.0953 | 0.1084 | 0.0633 | 0.0699 | 0.0954 | 0.0979 | 0.6595 | 0.6304 | 0.0004 | 0.0017 | 0.0044 | 0.0151 | 0.0498 | 0.0888 | 0.0599 | 0.0831 | 0.6968 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 900 | 171 | | 3930 | 11298 | 497.7 | 103.96 | 94.40 | 173.19 | 316 | 409 | 476 | 500 | 521 | 540 | 560 | 583 | 613 | 0.0641 | 724 | 0.847 | 112.54 | 33.02 | 4 | 0.0832 | 327 | 0.0011 | 32.58 | 7.096 | 0.2211 | 258499.0 | 139000000 | 76000000000 | 42400000000000 | 0.3874 | 0.2511 | 0.0008 | 0.0003 | 0.0015 | 0.0000 | 0.0057 | 0.0000 | 0.0069 | 0.0008 | 0.0413 | 0.0186 | 0.0462 | 0.0251 | 0.0569 | 0.0178 | 0.0810 | 0.0276 | 0.7597 | 0.9099 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0197 | 0.0186 | 0.0188 | 0.0251 | 0.0172 | 0.0178 | 0.0260 | 0.0276 | 0.9179 | 0.9099 | 0.0052 | 0.0000 | 0.0140 | 0.0000 | 0.0315 | 0.0000 | 0.0542 | 0.0000 | 0.0717 | 0.0000 | 0.0944 | 0.0000 | 0.1119 | 0.0000 | 0.1556 | 0.0000 | 0.4615 | 0.0000 | 0.0012 | 0.0042 | 0.0037 | 0.0108 | 0.0279 | 0.0396 | 0.0500 | 0.0629 | 0.7997 | 6 | 7 | 9 | 10 | 14 | 24 | 52 | 125 | 339 | 0.1266 | 21.37 | 4.235 | 0.6154 | 38902.8 | 22700000 | 15400000000 | 11500000000000 | 0.5106 | 0.1373 | 0.0416 | 0.0018 | 0.1323 | 0.0210 | 0.2420 | 0.0602 | 0.1739 | 0.1267 | 0.1815 | 0.2124 | 0.1361 | 0.2042 | 0.0586 | 0.1258 | 0.0265 | 0.1167 | 0.0076 | 0.1313 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0031 | 0.0015 | 0.0097 | 0.0106 | 0.0497 | 0.0439 | 0.0660 | 0.0569 | 0.0453 | 0.0375 | 0.0729 | 0.0623 | 0.7530 | 0.7860 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0013 | 0.0018 | 0.0139 | 0.0172 | 0.0499 | 0.0548 | 0.0820 | 0.0743 | 0.0465 | 0.0535 | 0.0714 | 0.0729 | 0.7342 | 0.7254 | 0.0008 | 0.0000 | 0.0015 | 0.0131 | 0.0528 | 0.0670 | 0.0466 | 0.0751 | 0.7432 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 407 | 716 | | 7114 | 12770 | 534.1 | 94.65 | 61.96 | 146.06 | 380 | 451 | 508 | 534 | 555 | 577 | 594 | 611 | 633 | 0.0662 | 846 | 0.850 | 97.59 | 26.25 | 2 | 0.0417 | 297 | 0.0011 | 32.30 | 7.208 | 0.2276 | 294243.0 | 166000000 | 95600000000 | 55900000000000 | 0.4540 | 0.2027 | 0.0002 | 0.0001 | 0.0009 | 0.0006 | 0.0015 | 0.0003 | 0.0052 | 0.0017 | 0.0232 | 0.0121 | 0.0462 | 0.0176 | 0.0420 | 0.0150 | 0.0641 | 0.0232 | 0.8167 | 0.9294 | 0.0002 | 0.0001 | 0.0003 | 0.0006 | 0.0002 | 0.0003 | 0.0007 | 0.0017 | 0.0128 | 0.0121 | 0.0245 | 0.0176 | 0.0130 | 0.0150 | 0.0239 | 0.0232 | 0.9245 | 0.9294 | 0.0121 | 0.0000 | 0.0208 | 0.0000 | 0.0363 | 0.0000 | 0.0813 | 0.0000 | 0.1142 | 0.0000 | 0.1280 | 0.0000 | 0.1090 | 0.0000 | 0.1228 | 0.0000 | 0.3754 | 0.0000 | 0.0005 | 0.0014 | 0.0054 | 0.0119 | 0.0261 | 0.0428 | 0.0447 | 0.0612 | 0.8061 | 9 | 10 | 11 | 12 | 13 | 15 | 17 | 33 | 165 | 0.1905 | 3.26 | 2.362 | 0.6175 | 25171.9 | 16600000 | 13100000000 | 11600000000000 | 0.6507 | 0.0699 | 0.0193 | 0.0057 | 0.1322 | 0.0086 | 0.2204 | 0.0743 | 0.1736 | 0.1329 | 0.1267 | 0.2157 | 0.0909 | 0.1571 | 0.0716 | 0.0929 | 0.0661 | 0.1114 | 0.0992 | 0.2014 | 0.0000 | 0.0008 | 0.0009 | 0.0008 | 0.0031 | 0.0028 | 0.0098 | 0.0102 | 0.0459 | 0.0468 | 0.0570 | 0.0533 | 0.0459 | 0.0403 | 0.0731 | 0.0744 | 0.7643 | 0.7706 | 0.0011 | 0.0006 | 0.0021 | 0.0017 | 0.0069 | 0.0040 | 0.0133 | 0.0108 | 0.0436 | 0.0483 | 0.0760 | 0.0802 | 0.0452 | 0.0495 | 0.0803 | 0.0870 | 0.7315 | 0.7180 | 0.0005 | 0.0019 | 0.0048 | 0.0150 | 0.0446 | 0.0650 | 0.0509 | 0.0805 | 0.7368 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1270 | 935 | | 2332 | 2784 | 77.0 | 17.41 | 147.31 | 171.19 | 57 | 63 | 67 | 71 | 75 | 79 | 84 | 90 | 98 | 0.1566 | 436 | 0.850 | 77.94 | 29.70 | 1 | 0.1038 | 242 | 0.0063 | 9.67 | 5.383 | 0.3501 | 6226.1 | 531430 | 48100000 | 4640000000 | 0.4627 | 0.1874 | 0.0013 | 0.0000 | 0.0038 | 0.0005 | 0.0089 | 0.0014 | 0.0335 | 0.0046 | 0.0772 | 0.0246 | 0.1392 | 0.0483 | 0.1512 | 0.0433 | 0.1980 | 0.0724 | 0.3871 | 0.8050 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0031 | 0.0000 | 0.0098 | 0.0013 | 0.0411 | 0.0183 | 0.0878 | 0.0404 | 0.0734 | 0.0243 | 0.1145 | 0.0469 | 0.6689 | 0.8688 | 0.0109 | 0.0189 | 0.0327 | 0.0189 | 0.0463 | 0.0566 | 0.1308 | 0.1509 | 0.1417 | 0.1887 | 0.1989 | 0.2264 | 0.1144 | 0.0943 | 0.1608 | 0.1321 | 0.1635 | 0.1132 | 0.0028 | 0.0123 | 0.0274 | 0.0482 | 0.1154 | 0.1703 | 0.1060 | 0.1552 | 0.3623 | 13 | 16 | 21 | 34 | 74 | 129 | 190 | 273 | 377 | 0.0284 | 57.62 | 5.532 | 0.4008 | 50997.4 | 24600000 | 14500000000 | 9660000000000 | 0.5052 | 0.1542 | 0.0789 | 0.0074 | 0.2366 | 0.0391 | 0.2258 | 0.1657 | 0.1075 | 0.1304 | 0.1004 | 0.1657 | 0.1183 | 0.1657 | 0.0824 | 0.1229 | 0.0323 | 0.0838 | 0.0179 | 0.1192 | 0.0017 | 0.0000 | 0.0017 | 0.0008 | 0.0051 | 0.0084 | 0.0146 | 0.0114 | 0.0788 | 0.0729 | 0.1311 | 0.1109 | 0.0874 | 0.0858 | 0.1482 | 0.1291 | 0.5313 | 0.5809 | 0.0011 | 0.0000 | 0.0045 | 0.0064 | 0.0124 | 0.0141 | 0.0236 | 0.0295 | 0.1025 | 0.1013 | 0.1577 | 0.1782 | 0.1092 | 0.1115 | 0.1441 | 0.1449 | 0.4448 | 0.4141 | 0.0020 | 0.0039 | 0.0039 | 0.0225 | 0.1000 | 0.1324 | 0.1049 | 0.1471 | 0.4833 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 849 | | 5669 | 11631 | 149.6 | 30.26 | 380.14 | 292.12 | 115 | 126 | 133 | 140 | 146 | 153 | 161 | 172 | 189 | 0.0978 | 1138 | 0.853 | 87.32 | 20.22 | 4 | 0.0376 | 213 | 0.0246 | 2.00 | 4.135 | 0.5882 | 23308.7 | 3780000 | 639000000 | 113000000000 | 0.4512 | 0.2143 | 0.0005 | 0.0000 | 0.0019 | 0.0004 | 0.0066 | 0.0006 | 0.0209 | 0.0047 | 0.0542 | 0.0190 | 0.1074 | 0.0594 | 0.1031 | 0.0456 | 0.1449 | 0.0760 | 0.5605 | 0.7945 | 0.0002 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0005 | 0.0087 | 0.0041 | 0.0281 | 0.0148 | 0.0485 | 0.0422 | 0.0396 | 0.0185 | 0.0686 | 0.0351 | 0.8028 | 0.8846 | 0.0072 | 0.0165 | 0.0217 | 0.0535 | 0.0253 | 0.0535 | 0.0939 | 0.1934 | 0.1721 | 0.2058 | 0.1877 | 0.1934 | 0.1095 | 0.0864 | 0.1300 | 0.0947 | 0.2527 | 0.1029 | 0.0031 | 0.0043 | 0.0152 | 0.0390 | 0.0928 | 0.1383 | 0.1200 | 0.1380 | 0.4493 | 68 | 117 | 173 | 239 | 313 | 389 | 493 | 610 | 797 | 0.0026 | 36.91 | 6.778 | 0.2991 | 229829.0 | 180000000 | 166000000000 | 173000000000000 | 0.5041 | 0.1494 | 0.0174 | 0.0017 | 0.0886 | 0.0073 | 0.1781 | 0.0403 | 0.1658 | 0.0825 | 0.1856 | 0.1556 | 0.1451 | 0.1874 | 0.0933 | 0.1449 | 0.0612 | 0.1473 | 0.0650 | 0.2330 | 0.0002 | 0.0000 | 0.0023 | 0.0006 | 0.0058 | 0.0035 | 0.0167 | 0.0122 | 0.0657 | 0.0480 | 0.1189 | 0.0967 | 0.0796 | 0.0703 | 0.1194 | 0.1013 | 0.5913 | 0.6674 | 0.0015 | 0.0013 | 0.0036 | 0.0039 | 0.0103 | 0.0186 | 0.0328 | 0.0417 | 0.0904 | 0.1037 | 0.1420 | 0.1637 | 0.1030 | 0.1027 | 0.1258 | 0.1376 | 0.4904 | 0.4266 | 0.0006 | 0.0031 | 0.0121 | 0.0249 | 0.0804 | 0.1317 | 0.0936 | 0.1214 | 0.5321 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 271 | 234 | | 4849 | 8509 | 138.5 | 37.61 | 168.08 | 116.27 | 97 | 108 | 116 | 125 | 133 | 143 | 153 | 166 | 185 | 0.0903 | 768 | 0.853 | 97.87 | 27.20 | 1 | 0.0524 | 254 | 0.0019 | 23.69 | 6.561 | 0.2428 | 20609.1 | 3310000 | 576000000 | 109000000000 | 0.4479 | 0.1970 | 0.0011 | 0.0000 | 0.0041 | 0.0000 | 0.0103 | 0.0007 | 0.0347 | 0.0030 | 0.0975 | 0.0240 | 0.1680 | 0.0552 | 0.1473 | 0.0550 | 0.1743 | 0.0965 | 0.3626 | 0.7657 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0030 | 0.0000 | 0.0123 | 0.0013 | 0.0355 | 0.0161 | 0.0695 | 0.0309 | 0.0711 | 0.0237 | 0.0993 | 0.0428 | 0.7066 | 0.8852 | 0.0042 | 0.0206 | 0.0084 | 0.0413 | 0.0190 | 0.0324 | 0.0685 | 0.1150 | 0.1496 | 0.1711 | 0.1707 | 0.1917 | 0.1201 | 0.1003 | 0.1465 | 0.0944 | 0.3130 | 0.2330 | 0.0009 | 0.0047 | 0.0117 | 0.0314 | 0.0835 | 0.1234 | 0.1183 | 0.1427 | 0.4833 | 38 | 66 | 89 | 113 | 143 | 180 | 216 | 263 | 330 | 0.0018 | 46.51 | 6.975 | 0.2588 | 41766.1 | 13000000 | 4740000000 | 1930000000000 | 0.4999 | 0.1620 | 0.0124 | 0.0018 | 0.0599 | 0.0036 | 0.1785 | 0.0173 | 0.2094 | 0.0574 | 0.1872 | 0.1344 | 0.1408 | 0.2044 | 0.0982 | 0.1652 | 0.0624 | 0.1709 | 0.0513 | 0.2450 | 0.0000 | 0.0005 | 0.0009 | 0.0009 | 0.0025 | 0.0038 | 0.0156 | 0.0096 | 0.0467 | 0.0356 | 0.0847 | 0.0597 | 0.0774 | 0.0637 | 0.1241 | 0.0957 | 0.6481 | 0.7305 | 0.0014 | 0.0023 | 0.0028 | 0.0064 | 0.0084 | 0.0138 | 0.0298 | 0.0527 | 0.0922 | 0.1087 | 0.1388 | 0.1577 | 0.1247 | 0.1220 | 0.1496 | 0.1298 | 0.4523 | 0.4067 | 0.0000 | 0.0008 | 0.0024 | 0.0176 | 0.0680 | 0.1114 | 0.0973 | 0.1403 | 0.5622 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1049 | 270 | | 3875 | 7952 | 133.1 | 35.91 | 157.83 | 125.74 | 94 | 104 | 113 | 121 | 128 | 136 | 145 | 157 | 179 | 0.0832 | 662 | 0.854 | 78.82 | 25.55 | 2 | 0.0565 | 219 | 0.0020 | 26.25 | 6.494 | 0.2455 | 18997.6 | 2930000 | 490000000 | 89600000000 | 0.4209 | 0.2213 | 0.0000 | 0.0003 | 0.0004 | 0.0000 | 0.0074 | 0.0003 | 0.0302 | 0.0020 | 0.0944 | 0.0294 | 0.1627 | 0.0582 | 0.1605 | 0.0616 | 0.1828 | 0.0913 | 0.3616 | 0.7570 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0030 | 0.0000 | 0.0097 | 0.0003 | 0.0462 | 0.0196 | 0.0716 | 0.0346 | 0.0726 | 0.0291 | 0.1044 | 0.0471 | 0.6921 | 0.8694 | 0.0086 | 0.0097 | 0.0143 | 0.0065 | 0.0399 | 0.0259 | 0.0799 | 0.1003 | 0.1241 | 0.1586 | 0.1526 | 0.1715 | 0.0984 | 0.1100 | 0.1184 | 0.1683 | 0.3638 | 0.2492 | 0.0024 | 0.0083 | 0.0166 | 0.0391 | 0.1073 | 0.1375 | 0.1203 | 0.1316 | 0.4369 | 26 | 44 | 68 | 98 | 128 | 163 | 203 | 251 | 336 | 0.0035 | 41.32 | 6.588 | 0.3220 | 40720.6 | 13800000 | 5550000000 | 2540000000000 | 0.4558 | 0.2138 | 0.0196 | 0.0022 | 0.0713 | 0.0072 | 0.1578 | 0.0421 | 0.1767 | 0.0623 | 0.2000 | 0.1326 | 0.1804 | 0.1870 | 0.1084 | 0.1581 | 0.0531 | 0.1675 | 0.0327 | 0.2410 | 0.0012 | 0.0000 | 0.0015 | 0.0021 | 0.0055 | 0.0037 | 0.0159 | 0.0118 | 0.0585 | 0.0468 | 0.0938 | 0.0773 | 0.0774 | 0.0664 | 0.1074 | 0.0880 | 0.6388 | 0.7040 | 0.0008 | 0.0034 | 0.0053 | 0.0087 | 0.0120 | 0.0135 | 0.0361 | 0.0429 | 0.0847 | 0.1118 | 0.1295 | 0.1301 | 0.1043 | 0.1186 | 0.1401 | 0.1533 | 0.4872 | 0.4178 | 0.0006 | 0.0033 | 0.0108 | 0.0222 | 0.0752 | 0.1049 | 0.0869 | 0.1254 | 0.5707 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 508 | 133 | | 5112 | 15953 | 596.9 | 122.93 | 209.99 | 332.25 | 447 | 490 | 521 | 552 | 585 | 617 | 653 | 698 | 767 | 0.0564 | 899 | 0.855 | 86.15 | 24.76 | 1 | 0.0428 | 219 | 0.0004 | 156.57 | 7.925 | 0.1053 | 371349.0 | 241000000 | 162000000000 | 113000000000000 | 0.4423 | 0.2051 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0187 | 0.0008 | 0.0672 | 0.0192 | 0.1466 | 0.0410 | 0.1398 | 0.0373 | 0.1694 | 0.0551 | 0.4551 | 0.8466 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0089 | 0.0004 | 0.0325 | 0.0132 | 0.0678 | 0.0246 | 0.0610 | 0.0151 | 0.0909 | 0.0305 | 0.7386 | 0.9162 | 0.0023 | 0.0043 | 0.0103 | 0.0043 | 0.0195 | 0.0468 | 0.0736 | 0.1319 | 0.1310 | 0.1872 | 0.2080 | 0.2468 | 0.1023 | 0.0936 | 0.1264 | 0.1106 | 0.3264 | 0.1745 | 0.0008 | 0.0025 | 0.0105 | 0.0257 | 0.0758 | 0.1281 | 0.1049 | 0.1184 | 0.5333 | 8 | 10 | 12 | 14 | 20 | 73 | 208 | 417 | 696 | 0.1770 | 37.47 | 4.561 | 0.5961 | 154477.0 | 156000000 | 189000000000 | 260000000000000 | 0.5567 | 0.1171 | 0.0435 | 0.0017 | 0.1317 | 0.0133 | 0.1719 | 0.0920 | 0.1462 | 0.1123 | 0.1551 | 0.1516 | 0.1272 | 0.1707 | 0.1071 | 0.1244 | 0.0737 | 0.1291 | 0.0435 | 0.2049 | 0.0000 | 0.0003 | 0.0002 | 0.0000 | 0.0013 | 0.0010 | 0.0089 | 0.0045 | 0.0312 | 0.0322 | 0.0618 | 0.0501 | 0.0532 | 0.0353 | 0.0709 | 0.0694 | 0.7724 | 0.8070 | 0.0005 | 0.0002 | 0.0000 | 0.0007 | 0.0023 | 0.0015 | 0.0087 | 0.0100 | 0.0449 | 0.0500 | 0.0795 | 0.0826 | 0.0525 | 0.0585 | 0.0887 | 0.0933 | 0.7230 | 0.7032 | 0.0008 | 0.0015 | 0.0023 | 0.0088 | 0.0390 | 0.0736 | 0.0524 | 0.0793 | 0.7423 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 145 | 220 | | 5756 | 11661 | 118.5 | 36.39 | 167.20 | 124.25 | 81 | 90 | 98 | 104 | 111 | 118 | 128 | 143 | 165 | 0.0846 | 986 | 0.856 | 102.96 | 27.00 | 1 | 0.0480 | 276 | 0.0023 | 23.04 | 6.430 | 0.2521 | 15367.1 | 2200000 | 352000000 | 62600000000 | 0.4200 | 0.2279 | 0.0020 | 0.0000 | 0.0029 | 0.0002 | 0.0150 | 0.0010 | 0.0444 | 0.0056 | 0.1120 | 0.0292 | 0.1639 | 0.0606 | 0.1681 | 0.0606 | 0.2099 | 0.0964 | 0.2818 | 0.7463 | 0.0014 | 0.0000 | 0.0009 | 0.0000 | 0.0050 | 0.0007 | 0.0159 | 0.0020 | 0.0515 | 0.0182 | 0.0735 | 0.0309 | 0.0871 | 0.0309 | 0.1288 | 0.0545 | 0.6358 | 0.8628 | 0.0043 | 0.0018 | 0.0130 | 0.0107 | 0.0260 | 0.0178 | 0.0582 | 0.0516 | 0.1094 | 0.1335 | 0.1432 | 0.2046 | 0.1102 | 0.1174 | 0.1363 | 0.1459 | 0.3993 | 0.3167 | 0.0030 | 0.0057 | 0.0174 | 0.0449 | 0.0858 | 0.1233 | 0.1054 | 0.1337 | 0.4808 | 25 | 50 | 81 | 110 | 144 | 177 | 218 | 274 | 343 | 0.0021 | 46.18 | 7.043 | 0.2601 | 43391.7 | 14100000 | 5330000000 | 2240000000000 | 0.5309 | 0.1392 | 0.0066 | 0.0007 | 0.0509 | 0.0066 | 0.1329 | 0.0201 | 0.1554 | 0.0531 | 0.1718 | 0.1357 | 0.1718 | 0.1713 | 0.1337 | 0.1501 | 0.1001 | 0.1692 | 0.0766 | 0.2933 | 0.0002 | 0.0003 | 0.0019 | 0.0009 | 0.0047 | 0.0031 | 0.0146 | 0.0122 | 0.0480 | 0.0427 | 0.0812 | 0.0603 | 0.0796 | 0.0606 | 0.1017 | 0.0883 | 0.6681 | 0.7316 | 0.0018 | 0.0022 | 0.0028 | 0.0073 | 0.0117 | 0.0105 | 0.0273 | 0.0350 | 0.0734 | 0.0815 | 0.1175 | 0.1238 | 0.0948 | 0.0986 | 0.1233 | 0.1371 | 0.5474 | 0.5040 | 0.0018 | 0.0034 | 0.0086 | 0.0243 | 0.0633 | 0.0955 | 0.0865 | 0.1196 | 0.5971 | ||
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 266 | 404 | | 2278 | 9177 | 440.8 | 82.93 | 18.18 | 14.33 | 329 | 363 | 393 | 419 | 442 | 462 | 484 | 509 | 554 | 0.0623 | 572 | 0.857 | 85.43 | 24.17 | 1 | 0.0979 | 223 | 0.0015 | 22.45 | 6.709 | 0.2343 | 201189.0 | 94800000 | 46100000000 | 23000000000000 | 0.3824 | 0.2567 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0045 | 0.0000 | 0.0102 | 0.0013 | 0.0447 | 0.0224 | 0.0735 | 0.0385 | 0.0671 | 0.0251 | 0.0927 | 0.0354 | 0.7073 | 0.8772 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0042 | 0.0004 | 0.0221 | 0.0184 | 0.0390 | 0.0347 | 0.0269 | 0.0158 | 0.0421 | 0.0237 | 0.8635 | 0.9069 | 0.0030 | 0.0222 | 0.0090 | 0.0000 | 0.0270 | 0.0889 | 0.0450 | 0.0889 | 0.0601 | 0.2000 | 0.1141 | 0.1333 | 0.1171 | 0.1778 | 0.1081 | 0.1333 | 0.5165 | 0.1556 | 0.0000 | 0.0009 | 0.0035 | 0.0130 | 0.0496 | 0.0696 | 0.0600 | 0.0904 | 0.7130 | 9 | 11 | 12 | 14 | 15 | 17 | 19 | 22 | 28 | 0.2118 | 0.79 | 1.993 | 0.8257 | 536.0 | 35898.2 | 4390000 | 666000000 | 0.5182 | 0.1416 | 0.0551 | 0.0050 | 0.0834 | 0.0121 | 0.1015 | 0.0296 | 0.1367 | 0.0539 | 0.1535 | 0.0819 | 0.1890 | 0.1115 | 0.1671 | 0.1301 | 0.0914 | 0.1928 | 0.0223 | 0.3829 | 0.0260 | 0.0018 | 0.0361 | 0.0067 | 0.0367 | 0.0183 | 0.0476 | 0.0364 | 0.0429 | 0.0592 | 0.0677 | 0.0813 | 0.0851 | 0.0830 | 0.1435 | 0.1084 | 0.5144 | 0.6048 | 0.0291 | 0.0429 | 0.0530 | 0.0429 | 0.0540 | 0.0429 | 0.0673 | 0.0648 | 0.0726 | 0.0843 | 0.1017 | 0.1199 | 0.0984 | 0.1240 | 0.1437 | 0.1337 | 0.3801 | 0.3444 | 0.0322 | 0.0313 | 0.0342 | 0.0453 | 0.0664 | 0.0914 | 0.1047 | 0.1395 | 0.4549 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 153 | 139 | | 5758 | 11802 | 360.4 | 40.57 | 302.04 | 287.41 | 307 | 326 | 339 | 350 | 361 | 372 | 383 | 396 | 412 | 0.0835 | 986 | 0.859 | 110.32 | 27.29 | 1 | 0.0455 | 262 | 0.0019 | 22.05 | 6.508 | 0.2365 | 131562.0 | 48600000 | 18200000000 | 6860000000000 | 0.4593 | 0.1900 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0011 | 0.0000 | 0.0030 | 0.0002 | 0.0199 | 0.0116 | 0.0345 | 0.0200 | 0.0450 | 0.0106 | 0.0849 | 0.0181 | 0.8109 | 0.9396 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0002 | 0.0165 | 0.0116 | 0.0244 | 0.0200 | 0.0244 | 0.0106 | 0.0400 | 0.0181 | 0.8916 | 0.9396 | 0.0419 | 0.0000 | 0.1204 | 0.0000 | 0.1414 | 0.0000 | 0.1204 | 0.0000 | 0.0942 | 0.0000 | 0.1204 | 0.0000 | 0.1099 | 0.0000 | 0.1099 | 0.0000 | 0.1414 | 0.0000 | 0.0027 | 0.0030 | 0.0172 | 0.0320 | 0.0573 | 0.1004 | 0.1018 | 0.1375 | 0.5480 | 23 | 35 | 59 | 111 | 207 | 327 | 442 | 575 | 737 | 0.0095 | 68.30 | 6.730 | 0.3226 | 173824.0 | 123000000 | 98700000000 | 86100000000000 | 0.4300 | 0.1996 | 0.0309 | 0.0016 | 0.1561 | 0.0094 | 0.2346 | 0.0661 | 0.1920 | 0.1351 | 0.1669 | 0.2033 | 0.1068 | 0.2090 | 0.0576 | 0.1286 | 0.0434 | 0.1167 | 0.0117 | 0.1302 | 0.0002 | 0.0000 | 0.0004 | 0.0002 | 0.0011 | 0.0013 | 0.0078 | 0.0063 | 0.0446 | 0.0401 | 0.0822 | 0.0683 | 0.0522 | 0.0435 | 0.0816 | 0.0691 | 0.7299 | 0.7711 | 0.0005 | 0.0003 | 0.0007 | 0.0019 | 0.0032 | 0.0051 | 0.0178 | 0.0177 | 0.0597 | 0.0756 | 0.1097 | 0.1293 | 0.0834 | 0.0942 | 0.1134 | 0.1322 | 0.6116 | 0.5437 | 0.0000 | 0.0002 | 0.0008 | 0.0107 | 0.0530 | 0.0945 | 0.0643 | 0.1014 | 0.6751 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 658 | 779 | | 5169 | 11172 | 137.7 | 32.46 | 113.17 | 91.87 | 100 | 111 | 120 | 127 | 134 | 142 | 150 | 160 | 178 | 0.0719 | 803 | 0.859 | 104.81 | 28.16 | 1 | 0.0530 | 274 | 0.0021 | 21.91 | 6.455 | 0.2447 | 20003.2 | 3080000 | 502000000 | 87100000000 | 0.4380 | 0.2131 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0072 | 0.0000 | 0.0208 | 0.0021 | 0.0760 | 0.0199 | 0.1417 | 0.0475 | 0.1466 | 0.0488 | 0.1981 | 0.0785 | 0.4089 | 0.8031 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0077 | 0.0008 | 0.0363 | 0.0134 | 0.0672 | 0.0294 | 0.0593 | 0.0203 | 0.0997 | 0.0401 | 0.7272 | 0.8959 | 0.0081 | 0.0139 | 0.0185 | 0.0209 | 0.0288 | 0.0453 | 0.0819 | 0.1603 | 0.1453 | 0.1672 | 0.1926 | 0.1812 | 0.1119 | 0.0836 | 0.1407 | 0.1324 | 0.2722 | 0.1951 | 0.0025 | 0.0042 | 0.0148 | 0.0420 | 0.0954 | 0.1238 | 0.1081 | 0.1361 | 0.4731 | 15 | 30 | 49 | 70 | 92 | 118 | 149 | 185 | 238 | 0.0049 | 34.56 | 6.477 | 0.3146 | 21247.0 | 5290000 | 1630000000 | 593000000000 | 0.5230 | 0.1320 | 0.0237 | 0.0013 | 0.1084 | 0.0065 | 0.2323 | 0.0500 | 0.1730 | 0.0940 | 0.1806 | 0.1655 | 0.1412 | 0.2079 | 0.0846 | 0.1542 | 0.0415 | 0.1364 | 0.0146 | 0.1841 | 0.0004 | 0.0003 | 0.0009 | 0.0000 | 0.0057 | 0.0022 | 0.0210 | 0.0114 | 0.0670 | 0.0515 | 0.1169 | 0.0950 | 0.0867 | 0.0772 | 0.1217 | 0.1026 | 0.5799 | 0.6597 | 0.0011 | 0.0007 | 0.0029 | 0.0076 | 0.0111 | 0.0152 | 0.0315 | 0.0444 | 0.0978 | 0.1136 | 0.1574 | 0.1758 | 0.0999 | 0.1242 | 0.1479 | 0.1351 | 0.4505 | 0.3834 | 0.0009 | 0.0021 | 0.0064 | 0.0277 | 0.0813 | 0.1285 | 0.1054 | 0.1321 | 0.5156 | ||
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 568 | 142 | | 3390 | 3676 | 488.2 | 76.89 | 55.99 | 95.47 | 384 | 420 | 448 | 473 | 493 | 513 | 533 | 556 | 587 | 0.1317 | 484 | 0.859 | 109.18 | 23.32 | 5 | 0.0752 | 255 | 0.0012 | 41.51 | 6.959 | 0.2091 | 244289.0 | 125000000 | 65200000000 | 34600000000000 | 0.4456 | 0.2022 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0133 | 0.0009 | 0.0451 | 0.0139 | 0.0863 | 0.0237 | 0.0833 | 0.0160 | 0.1064 | 0.0261 | 0.6638 | 0.9194 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0050 | 0.0009 | 0.0220 | 0.0139 | 0.0441 | 0.0237 | 0.0414 | 0.0154 | 0.0588 | 0.0231 | 0.8284 | 0.9230 | 0.0028 | 0.0000 | 0.0113 | 1.0000 | 0.0395 | 0.0000 | 0.1073 | 0.0000 | 0.1638 | 0.0000 | 0.2147 | 0.0000 | 0.1243 | 0.0000 | 0.1356 | 0.0000 | 0.2006 | 0.0000 | 0.0006 | 0.0017 | 0.0045 | 0.0195 | 0.0658 | 0.1155 | 0.1016 | 0.1267 | 0.5642 | 9 | 11 | 12 | 14 | 17 | 20 | 25 | 75 | 169 | 0.1554 | 6.68 | 3.147 | 0.7267 | 12247.2 | 4240000 | 1770000000 | 834000000000 | 0.4752 | 0.1492 | 0.0192 | 0.0284 | 0.0769 | 0.0355 | 0.1731 | 0.1277 | 0.3462 | 0.1489 | 0.1346 | 0.1915 | 0.1346 | 0.1773 | 0.1154 | 0.1206 | 0.0000 | 0.0709 | 0.0000 | 0.0993 | 0.0000 | 0.0046 | 0.0025 | 0.0058 | 0.0012 | 0.0116 | 0.0037 | 0.0127 | 0.0160 | 0.0197 | 0.0197 | 0.0313 | 0.0271 | 0.0174 | 0.0406 | 0.0440 | 0.8892 | 0.8530 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0028 | 0.0039 | 0.0083 | 0.0211 | 0.0221 | 0.0316 | 0.0456 | 0.0395 | 0.0415 | 0.0684 | 0.0692 | 0.8329 | 0.8105 | 0.0000 | 0.0000 | 0.0013 | 0.0038 | 0.0189 | 0.0215 | 0.0278 | 0.0556 | 0.8712 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 125 | 813 | | 4044 | 8852 | 602.6 | 91.52 | 41.19 | 63.75 | 467 | 546 | 581 | 603 | 621 | 637 | 653 | 670 | 697 | 0.0916 | 811 | 0.861 | 103.18 | 25.63 | 4 | 0.0601 | 243 | 0.0019 | 32.85 | 6.649 | 0.2422 | 371488.0 | 233000000 | 149000000000 | 95900000000000 | 0.4344 | 0.2018 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0008 | 0.0262 | 0.0168 | 0.0455 | 0.0300 | 0.0385 | 0.0173 | 0.0691 | 0.0297 | 0.8172 | 0.9055 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0008 | 0.0201 | 0.0167 | 0.0321 | 0.0289 | 0.0201 | 0.0157 | 0.0338 | 0.0282 | 0.8928 | 0.9097 | 0.0279 | 0.0000 | 0.0391 | 0.0000 | 0.0615 | 0.1429 | 0.1006 | 0.2857 | 0.1006 | 0.2857 | 0.1564 | 0.2857 | 0.1229 | 0.0000 | 0.0950 | 0.0000 | 0.2961 | 0.0000 | 0.0008 | 0.0021 | 0.0062 | 0.0181 | 0.0402 | 0.0743 | 0.0812 | 0.0952 | 0.6820 | 9 | 11 | 14 | 16 | 19 | 24 | 32 | 45 | 88 | 0.0559 | 3.74 | 3.856 | 0.6364 | 5760.6 | 1520000 | 505000000 | 191000000000 | 0.4879 | 0.1680 | 0.0222 | 0.0179 | 0.0677 | 0.0335 | 0.0812 | 0.0288 | 0.1141 | 0.0594 | 0.1460 | 0.0957 | 0.1470 | 0.0868 | 0.1692 | 0.1094 | 0.1335 | 0.1627 | 0.1190 | 0.4059 | 0.0058 | 0.0099 | 0.0173 | 0.0192 | 0.0142 | 0.0128 | 0.0242 | 0.0271 | 0.0468 | 0.0434 | 0.0560 | 0.0449 | 0.0629 | 0.0545 | 0.0844 | 0.0813 | 0.6884 | 0.7067 | 0.0032 | 0.0069 | 0.0153 | 0.0122 | 0.0159 | 0.0130 | 0.0312 | 0.0298 | 0.0503 | 0.0519 | 0.0751 | 0.0833 | 0.0649 | 0.0596 | 0.0808 | 0.0795 | 0.6635 | 0.6639 | 0.0049 | 0.0113 | 0.0157 | 0.0300 | 0.0458 | 0.0679 | 0.0684 | 0.0915 | 0.6644 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 875 | 62 | | 1334 | 3820 | 91.9 | 21.30 | 105.54 | 80.69 | 68 | 74 | 80 | 85 | 90 | 95 | 100 | 106 | 117 | 0.1102 | 421 | 0.866 | 95.82 | 24.17 | 1 | 0.1807 | 241 | 0.0026 | 28.10 | 6.166 | 0.2282 | 8892.5 | 911642 | 99600000 | 11700000000 | 0.4476 | 0.2105 | 0.0034 | 0.0000 | 0.0056 | 0.0000 | 0.0213 | 0.0048 | 0.0369 | 0.0081 | 0.0884 | 0.0306 | 0.1432 | 0.0564 | 0.1454 | 0.0596 | 0.1946 | 0.0854 | 0.3613 | 0.7550 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0055 | 0.0000 | 0.0157 | 0.0023 | 0.0507 | 0.0235 | 0.1005 | 0.0454 | 0.0811 | 0.0310 | 0.1180 | 0.0613 | 0.6267 | 0.8365 | 0.0419 | 0.0125 | 0.0366 | 0.0375 | 0.0628 | 0.1000 | 0.0785 | 0.1000 | 0.1937 | 0.2125 | 0.2042 | 0.1000 | 0.0628 | 0.0750 | 0.0995 | 0.1375 | 0.2199 | 0.2250 | 0.0016 | 0.0128 | 0.0096 | 0.0465 | 0.1348 | 0.1750 | 0.1236 | 0.1637 | 0.3323 | 28 | 40 | 52 | 68 | 85 | 105 | 126 | 153 | 212 | 0.0130 | 7.64 | 5.068 | 0.4624 | 17649.0 | 4150000 | 1240000000 | 442000000000 | 0.4801 | 0.1727 | 0.0158 | 0.0013 | 0.0706 | 0.0076 | 0.1364 | 0.0297 | 0.1583 | 0.0607 | 0.1754 | 0.1208 | 0.1851 | 0.1720 | 0.1218 | 0.1562 | 0.0938 | 0.1720 | 0.0426 | 0.2796 | 0.0000 | 0.0000 | 0.0021 | 0.0017 | 0.0067 | 0.0050 | 0.0249 | 0.0184 | 0.0716 | 0.0537 | 0.1095 | 0.0910 | 0.0851 | 0.0746 | 0.1183 | 0.1065 | 0.5817 | 0.6491 | 0.0036 | 0.0062 | 0.0099 | 0.0075 | 0.0172 | 0.0249 | 0.0506 | 0.0634 | 0.1112 | 0.1045 | 0.1546 | 0.1505 | 0.1103 | 0.1256 | 0.1338 | 0.1381 | 0.4087 | 0.3794 | 0.0013 | 0.0072 | 0.0118 | 0.0301 | 0.0740 | 0.1382 | 0.0950 | 0.1434 | 0.4990 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1060 | 312 | | 8531 | 15239 | 406.2 | 51.13 | 226.15 | 245.25 | 342 | 364 | 380 | 392 | 404 | 416 | 431 | 449 | 474 | 0.0668 | 1018 | 0.868 | 57.87 | 17.89 | 1 | 0.0178 | 152 | 0.0013 | 38.37 | 6.954 | 0.1978 | 167626.0 | 70200000 | 29900000000 | 12900000000000 | 0.4561 | 0.1965 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0013 | 0.0000 | 0.0042 | 0.0000 | 0.0191 | 0.0097 | 0.0469 | 0.0162 | 0.0566 | 0.0088 | 0.0892 | 0.0171 | 0.7825 | 0.9482 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0011 | 0.0000 | 0.0126 | 0.0097 | 0.0255 | 0.0162 | 0.0268 | 0.0088 | 0.0439 | 0.0152 | 0.8900 | 0.9501 | 0.0146 | 1.0000 | 0.0419 | 0.0000 | 0.0419 | 0.0000 | 0.1129 | 0.0000 | 0.1548 | 0.0000 | 0.1876 | 0.0000 | 0.1220 | 0.0000 | 0.1275 | 0.0000 | 0.1967 | 0.0000 | 0.0026 | 0.0043 | 0.0115 | 0.0412 | 0.0740 | 0.1178 | 0.1135 | 0.1283 | 0.5068 | 15 | 19 | 31 | 68 | 137 | 220 | 311 | 421 | 569 | 0.0214 | 62.72 | 6.209 | 0.3748 | 111286.0 | 74000000 | 60400000000 | 58100000000000 | 0.5099 | 0.1391 | 0.0526 | 0.0022 | 0.1940 | 0.0114 | 0.2544 | 0.1134 | 0.1674 | 0.1438 | 0.1298 | 0.1878 | 0.1032 | 0.1837 | 0.0545 | 0.1188 | 0.0292 | 0.1096 | 0.0149 | 0.1292 | 0.0000 | 0.0001 | 0.0001 | 0.0004 | 0.0007 | 0.0003 | 0.0079 | 0.0047 | 0.0500 | 0.0399 | 0.0844 | 0.0694 | 0.0697 | 0.0522 | 0.1028 | 0.0844 | 0.6841 | 0.7486 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0027 | 0.0049 | 0.0148 | 0.0281 | 0.0769 | 0.0926 | 0.1317 | 0.1530 | 0.1039 | 0.1070 | 0.1377 | 0.1459 | 0.5322 | 0.4672 | 0.0000 | 0.0000 | 0.0020 | 0.0090 | 0.0602 | 0.1073 | 0.0860 | 0.1254 | 0.6102 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 182 | 324 | | 4862 | 8847 | 382.1 | 46.56 | 84.31 | 223.89 | 321 | 348 | 363 | 376 | 385 | 395 | 406 | 419 | 440 | 0.0849 | 751 | 0.869 | 141.40 | 42.45 | 2 | 0.0755 | 367 | 0.0020 | 27.89 | 6.580 | 0.2423 | 148135.0 | 58200000 | 23200000000 | 9310000000000 | 0.4327 | 0.2087 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0044 | 0.0000 | 0.0215 | 0.0134 | 0.0430 | 0.0245 | 0.0423 | 0.0117 | 0.0642 | 0.0210 | 0.8233 | 0.9294 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0153 | 0.0134 | 0.0306 | 0.0245 | 0.0237 | 0.0117 | 0.0317 | 0.0210 | 0.8966 | 0.9294 | 0.0214 | 0.0000 | 0.0856 | 0.0000 | 0.1016 | 0.0000 | 0.1283 | 0.0000 | 0.1176 | 0.0000 | 0.1444 | 0.0000 | 0.1016 | 0.0000 | 0.1123 | 0.0000 | 0.1872 | 0.0000 | 0.0019 | 0.0049 | 0.0106 | 0.0314 | 0.0538 | 0.0947 | 0.0981 | 0.1163 | 0.5883 | 8 | 9 | 11 | 12 | 13 | 15 | 20 | 43 | 199 | 0.1434 | 6.44 | 2.531 | 0.5616 | 57228.9 | 60400000 | 73600000000 | 96900000000000 | 0.7057 | 0.0462 | 0.0466 | 0.0000 | 0.0975 | 0.0157 | 0.2458 | 0.0747 | 0.1144 | 0.1041 | 0.1653 | 0.1434 | 0.1483 | 0.1945 | 0.1102 | 0.1611 | 0.0466 | 0.1336 | 0.0254 | 0.1729 | 0.0007 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0048 | 0.0144 | 0.0133 | 0.0390 | 0.0387 | 0.0787 | 0.0678 | 0.0568 | 0.0599 | 0.1026 | 0.0998 | 0.7066 | 0.7145 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0016 | 0.0009 | 0.0122 | 0.0192 | 0.0636 | 0.0603 | 0.0865 | 0.0857 | 0.0530 | 0.0594 | 0.1117 | 0.0970 | 0.6713 | 0.6740 | 0.0000 | 0.0008 | 0.0023 | 0.0129 | 0.0530 | 0.0802 | 0.0560 | 0.1104 | 0.6846 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 946 | 911 | | 326 | 5218 | 83.2 | 12.55 | 6.61 | 2.23 | 66 | 72 | 76 | 80 | 84 | 87 | 90 | 94 | 100 | 0.0922 | 481 | 0.870 | 40.79 | 10.82 | 5 | 0.2883 | 94 | 0.0484 | 1.29 | 3.265 | 0.6193 | 7072.0 | 613833 | 54300000 | 4880000000 | 0.3970 | 0.2342 | 0.0039 | 0.0000 | 0.0039 | 0.0000 | 0.0078 | 0.0000 | 0.0310 | 0.0153 | 0.0698 | 0.0429 | 0.1512 | 0.0798 | 0.1163 | 0.0583 | 0.1860 | 0.0828 | 0.4302 | 0.7209 | 0.0034 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0206 | 0.0153 | 0.0309 | 0.0429 | 0.0997 | 0.0798 | 0.0550 | 0.0583 | 0.0928 | 0.0828 | 0.6907 | 0.7209 | 0.0303 | 0.0000 | 0.0909 | 0.0000 | 0.0909 | 0.0000 | 0.1818 | 0.0000 | 0.1818 | 0.0000 | 0.2121 | 0.0000 | 0.1212 | 0.0000 | 0.0606 | 0.0000 | 0.0303 | 0.0000 | 0.0055 | 0.0000 | 0.0110 | 0.0440 | 0.0714 | 0.1484 | 0.1154 | 0.2033 | 0.4011 | 4 | 5 | 6 | 6 | 6 | 7 | 7 | 9 | 9 | 0.0270 | 9.36 | 4.124 | 0.3431 | 48.6 | 391.422 | 3419.3 | 32319.8 | 0.5324 | 0.1461 | 0.0043 | 0.0011 | 0.0274 | 0.0040 | 0.0990 | 0.0214 | 0.1877 | 0.0631 | 0.2444 | 0.1213 | 0.2369 | 0.2069 | 0.1372 | 0.2618 | 0.0545 | 0.2256 | 0.0086 | 0.0948 | 0.0005 | 0.0002 | 0.0028 | 0.0019 | 0.0165 | 0.0091 | 0.0505 | 0.0369 | 0.1170 | 0.0831 | 0.1931 | 0.1470 | 0.2540 | 0.2323 | 0.2307 | 0.2820 | 0.1350 | 0.2075 | 0.1429 | 0.4528 | 0.2778 | 0.2397 | 0.2169 | 0.0896 | 0.1614 | 0.0557 | 0.0750 | 0.0436 | 0.0547 | 0.0533 | 0.0335 | 0.0412 | 0.0247 | 0.0194 | 0.0132 | 0.0048 | 0.0201 | 0.0768 | 0.1695 | 0.2209 | 0.1962 | 0.1531 | 0.0866 | 0.0497 | 0.0271 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 886 | 459 | | 3618 | 10342 | 579.4 | 120.00 | 16.41 | 14.61 | 402 | 502 | 541 | 570 | 596 | 621 | 644 | 667 | 707 | 0.0617 | 638 | 0.872 | 72.47 | 21.02 | 4 | 0.0506 | 183 | 0.0010 | 57.19 | 7.152 | 0.1994 | 350122.0 | 218000000 | 140000000000 | 91900000000000 | 0.4429 | 0.2126 | 0.0004 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0006 | 0.0086 | 0.0012 | 0.0409 | 0.0173 | 0.0601 | 0.0352 | 0.0530 | 0.0212 | 0.0823 | 0.0391 | 0.7539 | 0.8852 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0013 | 0.0009 | 0.0167 | 0.0167 | 0.0279 | 0.0301 | 0.0196 | 0.0140 | 0.0382 | 0.0289 | 0.8963 | 0.9084 | 0.0088 | 0.0000 | 0.0044 | 0.0980 | 0.0199 | 0.0000 | 0.0508 | 0.0980 | 0.1258 | 0.1569 | 0.1523 | 0.1765 | 0.1192 | 0.0588 | 0.1501 | 0.1373 | 0.3687 | 0.2745 | 0.0000 | 0.0005 | 0.0063 | 0.0146 | 0.0466 | 0.0777 | 0.0670 | 0.0869 | 0.7005 | 6 | 8 | 9 | 11 | 13 | 15 | 17 | 20 | 29 | 0.2798 | 0.41 | 1.932 | 0.8610 | 482.7 | 28156.6 | 2820000 | 388000000 | 0.4309 | 0.2072 | 0.0435 | 0.0205 | 0.0470 | 0.0372 | 0.0509 | 0.0455 | 0.0895 | 0.0516 | 0.1126 | 0.0612 | 0.1545 | 0.0846 | 0.2073 | 0.1008 | 0.1905 | 0.1706 | 0.1043 | 0.4280 | 0.0225 | 0.0151 | 0.0206 | 0.0257 | 0.0213 | 0.0301 | 0.0324 | 0.0319 | 0.0506 | 0.0421 | 0.0689 | 0.0635 | 0.0845 | 0.0648 | 0.1386 | 0.1026 | 0.5606 | 0.6242 | 0.0382 | 0.0267 | 0.0326 | 0.0130 | 0.0336 | 0.0298 | 0.0424 | 0.0360 | 0.0559 | 0.0477 | 0.0634 | 0.0701 | 0.0662 | 0.0775 | 0.1058 | 0.0967 | 0.5620 | 0.6026 | 0.0209 | 0.0300 | 0.0386 | 0.0551 | 0.0695 | 0.0973 | 0.0921 | 0.1086 | 0.4879 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1060 | 148 | | 9173 | 22344 | 294.9 | 54.87 | 142.27 | 167.42 | 227 | 246 | 262 | 276 | 290 | 304 | 321 | 343 | 371 | 0.0689 | 1540 | 0.872 | 128.71 | 44.38 | 1 | 0.0395 | 362 | 0.0007 | 53.70 | 7.461 | 0.1589 | 89976.7 | 28400000 | 9240000000 | 3100000000000 | 0.4189 | 0.2273 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0039 | 0.0000 | 0.0119 | 0.0010 | 0.0544 | 0.0105 | 0.1011 | 0.0239 | 0.1296 | 0.0218 | 0.1648 | 0.0345 | 0.5330 | 0.9084 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0059 | 0.0002 | 0.0246 | 0.0088 | 0.0420 | 0.0180 | 0.0587 | 0.0104 | 0.0811 | 0.0154 | 0.7860 | 0.9472 | 0.0035 | 0.0359 | 0.0110 | 0.0256 | 0.0311 | 0.0769 | 0.0876 | 0.1487 | 0.1090 | 0.1436 | 0.1739 | 0.1641 | 0.1256 | 0.1128 | 0.1387 | 0.1231 | 0.3195 | 0.1692 | 0.0012 | 0.0047 | 0.0077 | 0.0323 | 0.0798 | 0.1131 | 0.0949 | 0.1254 | 0.5411 | 14 | 17 | 22 | 39 | 72 | 114 | 176 | 260 | 379 | 0.0282 | 29.29 | 5.688 | 0.4480 | 48267.7 | 23800000 | 15100000000 | 12000000000000 | 0.5526 | 0.1273 | 0.0495 | 0.0023 | 0.1676 | 0.0182 | 0.2382 | 0.0872 | 0.1820 | 0.1262 | 0.1201 | 0.1819 | 0.1042 | 0.1777 | 0.0735 | 0.1315 | 0.0360 | 0.1131 | 0.0288 | 0.1618 | 0.0010 | 0.0004 | 0.0013 | 0.0008 | 0.0025 | 0.0027 | 0.0122 | 0.0114 | 0.0574 | 0.0459 | 0.1001 | 0.0810 | 0.0689 | 0.0643 | 0.0971 | 0.0872 | 0.6595 | 0.7063 | 0.0003 | 0.0003 | 0.0007 | 0.0013 | 0.0044 | 0.0053 | 0.0173 | 0.0217 | 0.0820 | 0.0881 | 0.1194 | 0.1360 | 0.0834 | 0.0891 | 0.1164 | 0.1154 | 0.5761 | 0.5428 | 0.0005 | 0.0013 | 0.0029 | 0.0153 | 0.0705 | 0.1085 | 0.0767 | 0.1091 | 0.6152 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 532 | 259 | | 3712 | 5457 | 168.2 | 45.22 | 152.55 | 98.18 | 118 | 130 | 141 | 151 | 161 | 171 | 183 | 199 | 228 | 0.1063 | 580 | 0.874 | 81.88 | 22.63 | 1 | 0.0568 | 211 | 0.0014 | 50.43 | 6.887 | 0.1876 | 30320.2 | 5890000 | 1230000000 | 278000000000 | 0.4069 | 0.2403 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0062 | 0.0000 | 0.0317 | 0.0030 | 0.1075 | 0.0290 | 0.1833 | 0.0635 | 0.1611 | 0.0635 | 0.1701 | 0.0982 | 0.3382 | 0.7428 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0000 | 0.0092 | 0.0008 | 0.0427 | 0.0178 | 0.0828 | 0.0324 | 0.0732 | 0.0250 | 0.0970 | 0.0453 | 0.6925 | 0.8788 | 0.0043 | 0.0098 | 0.0085 | 0.0131 | 0.0199 | 0.0359 | 0.0641 | 0.1242 | 0.1709 | 0.1797 | 0.1966 | 0.2222 | 0.1040 | 0.1307 | 0.1496 | 0.1242 | 0.2821 | 0.1601 | 0.0006 | 0.0044 | 0.0087 | 0.0355 | 0.1060 | 0.1390 | 0.1228 | 0.1465 | 0.4364 | 47 | 67 | 88 | 108 | 132 | 156 | 187 | 227 | 288 | 0.0026 | 30.72 | 6.456 | 0.2975 | 32908.8 | 9090000 | 3020000000 | 1160000000000 | 0.5362 | 0.1215 | 0.0115 | 0.0020 | 0.0516 | 0.0061 | 0.1491 | 0.0235 | 0.1589 | 0.0465 | 0.1851 | 0.1266 | 0.1720 | 0.1828 | 0.1261 | 0.1517 | 0.0827 | 0.1485 | 0.0631 | 0.3123 | 0.0007 | 0.0008 | 0.0017 | 0.0011 | 0.0079 | 0.0030 | 0.0171 | 0.0129 | 0.0690 | 0.0487 | 0.1097 | 0.0810 | 0.0861 | 0.0732 | 0.1168 | 0.1001 | 0.5910 | 0.6792 | 0.0012 | 0.0008 | 0.0059 | 0.0096 | 0.0152 | 0.0241 | 0.0463 | 0.0643 | 0.1032 | 0.1230 | 0.1641 | 0.1873 | 0.1208 | 0.1270 | 0.1319 | 0.1367 | 0.4115 | 0.3272 | 0.0018 | 0.0009 | 0.0066 | 0.0331 | 0.0888 | 0.1391 | 0.1069 | 0.1343 | 0.4885 |