High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1110 | 560 | | 2334 | 4086 | 123.1 | 42.05 | 219.05 | 128.32 | 74 | 87 | 96 | 107 | 117 | 129 | 142 | 157 | 183 | 0.1216 | 497 | 1.080 | 108.23 | 35.38 | 1 | 0.1204 | 281 | 0.0009 | 90.87 | 7.214 | 0.1270 | 16914.4 | 2570000 | 424000000 | 75500000000 | 0.4870 | 0.1611 | 0.0000 | 0.0000 | 0.0062 | 0.0006 | 0.0503 | 0.0006 | 0.1077 | 0.0083 | 0.1877 | 0.0598 | 0.2236 | 0.1374 | 0.1549 | 0.1291 | 0.1251 | 0.1551 | 0.1446 | 0.5091 | 0.0000 | 0.0000 | 0.0013 | 0.0005 | 0.0013 | 0.0000 | 0.0139 | 0.0057 | 0.0606 | 0.0335 | 0.1205 | 0.0746 | 0.0833 | 0.0581 | 0.1091 | 0.0846 | 0.6101 | 0.7430 | 0.0016 | 0.0000 | 0.0049 | 0.0000 | 0.0148 | 0.0256 | 0.0590 | 0.1026 | 0.1426 | 0.1891 | 0.1672 | 0.1987 | 0.1344 | 0.1218 | 0.1656 | 0.1346 | 0.3098 | 0.2276 | 0.0000 | 0.0019 | 0.0104 | 0.0321 | 0.0888 | 0.1671 | 0.1048 | 0.1398 | 0.4551 | 74 | 103 | 134 | 163 | 195 | 230 | 276 | 327 | 396 | 0.0027 | 23.43 | 6.329 | 0.2976 | 64441.3 | 23200000 | 9650000000 | 4520000000000 | 0.5232 | 0.1346 | 0.0093 | 0.0010 | 0.0558 | 0.0031 | 0.1767 | 0.0135 | 0.1787 | 0.0556 | 0.1911 | 0.1329 | 0.1560 | 0.1989 | 0.1188 | 0.1848 | 0.0692 | 0.1776 | 0.0444 | 0.2326 | 0.0004 | 0.0003 | 0.0009 | 0.0007 | 0.0044 | 0.0031 | 0.0126 | 0.0097 | 0.0566 | 0.0384 | 0.1111 | 0.0746 | 0.0910 | 0.0695 | 0.1324 | 0.1126 | 0.5906 | 0.6911 | 0.0015 | 0.0041 | 0.0068 | 0.0021 | 0.0090 | 0.0155 | 0.0384 | 0.0671 | 0.1032 | 0.1405 | 0.1800 | 0.1736 | 0.1122 | 0.1395 | 0.1611 | 0.1736 | 0.3878 | 0.2841 | 0.0000 | 0.0023 | 0.0051 | 0.0277 | 0.0779 | 0.1429 | 0.1107 | 0.1440 | 0.4896 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 146 | 887 | | 7631 | 21436 | 727.6 | 138.83 | 177.21 | 164.76 | 559 | 609 | 647 | 680 | 711 | 747 | 788 | 842 | 928 | 0.0466 | 999 | 1.151 | 109.39 | 39.66 | 3 | 0.0358 | 273 | 0.0005 | 96.74 | 7.799 | 0.1272 | 548709.0 | 428000000 | 346000000000 | 288000000000000 | 0.4347 | 0.2091 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0098 | 0.0011 | 0.0577 | 0.0148 | 0.1275 | 0.0300 | 0.1226 | 0.0286 | 0.1538 | 0.0479 | 0.5265 | 0.8776 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0040 | 0.0001 | 0.0261 | 0.0111 | 0.0570 | 0.0203 | 0.0558 | 0.0116 | 0.0815 | 0.0188 | 0.7746 | 0.9381 | 0.0024 | 0.0271 | 0.0065 | 0.0226 | 0.0212 | 0.1041 | 0.0637 | 0.1719 | 0.1371 | 0.1900 | 0.1853 | 0.1900 | 0.1273 | 0.1538 | 0.1510 | 0.0860 | 0.3053 | 0.0543 | 0.0020 | 0.0038 | 0.0116 | 0.0358 | 0.0832 | 0.1282 | 0.1170 | 0.1331 | 0.4854 | 19 | 36 | 62 | 97 | 135 | 178 | 225 | 286 | 389 | 0.0094 | 25.15 | 6.072 | 0.3627 | 58546.5 | 27800000 | 17200000000 | 13100000000000 | 0.4795 | 0.1685 | 0.0412 | 0.0013 | 0.1579 | 0.0105 | 0.2563 | 0.0772 | 0.1701 | 0.1359 | 0.1559 | 0.1808 | 0.1097 | 0.2006 | 0.0682 | 0.1460 | 0.0319 | 0.1267 | 0.0087 | 0.1208 | 0.0003 | 0.0003 | 0.0011 | 0.0011 | 0.0045 | 0.0011 | 0.0186 | 0.0128 | 0.0660 | 0.0509 | 0.1297 | 0.1018 | 0.1036 | 0.0883 | 0.1381 | 0.1190 | 0.5381 | 0.6246 | 0.0013 | 0.0031 | 0.0053 | 0.0081 | 0.0151 | 0.0171 | 0.0419 | 0.0463 | 0.0956 | 0.1170 | 0.1640 | 0.1725 | 0.1258 | 0.1325 | 0.1545 | 0.1478 | 0.3965 | 0.3555 | 0.0009 | 0.0027 | 0.0070 | 0.0268 | 0.0857 | 0.1465 | 0.1242 | 0.1468 | 0.4593 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 347 | 300 | | 2888 | 7129 | 611.2 | 202.03 | 52.68 | 78.44 | 344 | 415 | 484 | 545 | 608 | 668 | 727 | 793 | 895 | 0.0933 | 665 | 0.692 | 73.88 | 19.31 | 5 | 0.0793 | 229 | 0.0006 | 88.70 | 7.545 | 0.1281 | 414341.0 | 304000000 | 237000000000 | 194000000000000 | 0.4195 | 0.2137 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0017 | 0.0014 | 0.0318 | 0.0028 | 0.1133 | 0.0503 | 0.2017 | 0.0878 | 0.1279 | 0.0617 | 0.1536 | 0.0897 | 0.3691 | 0.7061 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0008 | 0.0040 | 0.0012 | 0.0334 | 0.0335 | 0.0703 | 0.0467 | 0.0389 | 0.0283 | 0.0573 | 0.0463 | 0.7956 | 0.8432 | 0.0024 | 0.0000 | 0.0012 | 0.0050 | 0.0071 | 0.0075 | 0.0214 | 0.0150 | 0.0820 | 0.1075 | 0.1023 | 0.1425 | 0.0880 | 0.0650 | 0.0892 | 0.1175 | 0.6064 | 0.5400 | 0.0000 | 0.0000 | 0.0000 | 0.0077 | 0.0510 | 0.0944 | 0.0573 | 0.0839 | 0.7056 | 9 | 12 | 14 | 18 | 24 | 33 | 47 | 68 | 122 | 0.0416 | 14.75 | 4.364 | 0.5754 | 8927.3 | 2850000 | 1210000000 | 606000000000 | 0.5155 | 0.1457 | 0.0091 | 0.0030 | 0.0653 | 0.0089 | 0.1554 | 0.0244 | 0.2324 | 0.0654 | 0.1932 | 0.1426 | 0.1436 | 0.1717 | 0.1097 | 0.1794 | 0.0627 | 0.1747 | 0.0287 | 0.2299 | 0.0004 | 0.0014 | 0.0052 | 0.0037 | 0.0100 | 0.0071 | 0.0247 | 0.0216 | 0.0715 | 0.0632 | 0.1001 | 0.0781 | 0.0811 | 0.0784 | 0.1188 | 0.1055 | 0.5882 | 0.6410 | 0.0013 | 0.0024 | 0.0084 | 0.0102 | 0.0149 | 0.0071 | 0.0292 | 0.0314 | 0.0876 | 0.0949 | 0.1181 | 0.1459 | 0.0876 | 0.0933 | 0.1207 | 0.1231 | 0.5321 | 0.4918 | 0.0016 | 0.0058 | 0.0111 | 0.0329 | 0.0853 | 0.1081 | 0.0859 | 0.1171 | 0.5522 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 270 | 229 | | 650 | 7025 | 1251.1 | 283.87 | 11.58 | 3.56 | 859 | 957 | 1050 | 1150 | 1249 | 1356 | 1450 | 1553 | 1640 | 0.0757 | 532 | 1.003 | 35.47 | 12.37 | 1 | 0.1554 | 101 | 0.0018 | 76.01 | 6.355 | 0.1286 | 1650000.0 | 2260000000 | 3210000000000 | 4.71E+15 | 0.3546 | 0.2714 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0861 | 0.0357 | 0.1632 | 0.0683 | 0.0950 | 0.0233 | 0.1424 | 0.0714 | 0.5104 | 0.8012 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0405 | 0.0356 | 0.0729 | 0.0681 | 0.0304 | 0.0232 | 0.0547 | 0.0464 | 0.7996 | 0.8266 | 0.0000 | 1.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0127 | 0.0000 | 0.0828 | 0.0000 | 0.1083 | 0.0000 | 0.0573 | 0.0000 | 0.1083 | 0.0000 | 0.6306 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0093 | 0.0556 | 0.0710 | 0.0525 | 0.0556 | 0.7562 | 7 | 9 | 10 | 11 | 11 | 12 | 13 | 14 | 16 | 0.0081 | 16.06 | 5.190 | 0.2777 | 146.9 | 2017.49 | 29808.4 | 471003 | 0.4942 | 0.1529 | 0.0108 | 0.0007 | 0.0396 | 0.0047 | 0.0930 | 0.0132 | 0.1508 | 0.0346 | 0.2124 | 0.0636 | 0.2362 | 0.1307 | 0.1635 | 0.2187 | 0.0792 | 0.3144 | 0.0144 | 0.2194 | 0.0046 | 0.0002 | 0.0197 | 0.0029 | 0.0427 | 0.0088 | 0.0534 | 0.0212 | 0.0813 | 0.0412 | 0.1242 | 0.0726 | 0.1697 | 0.1078 | 0.2247 | 0.2453 | 0.2797 | 0.5001 | 0.1226 | 0.2147 | 0.1534 | 0.1587 | 0.1534 | 0.1635 | 0.1480 | 0.1346 | 0.1180 | 0.1010 | 0.0987 | 0.0737 | 0.0887 | 0.0561 | 0.0717 | 0.0657 | 0.0455 | 0.0321 | 0.0277 | 0.0639 | 0.0858 | 0.1141 | 0.1354 | 0.1515 | 0.1521 | 0.1263 | 0.1433 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 855 | 618 | | 6392 | 8692 | 565.9 | 136.42 | 151.51 | 154.48 | 405 | 449 | 487 | 519 | 551 | 583 | 618 | 669 | 747 | 0.0962 | 836 | 1.181 | 149.16 | 56.30 | 1 | 0.0601 | 384 | 0.0005 | 84.49 | 7.736 | 0.1296 | 338887.0 | 215000000 | 144000000000 | 102000000000000 | 0.4381 | 0.2035 | 0.0003 | 0.0000 | 0.0013 | 0.0002 | 0.0021 | 0.0003 | 0.0167 | 0.0026 | 0.0632 | 0.0204 | 0.1182 | 0.0408 | 0.1292 | 0.0333 | 0.1665 | 0.0493 | 0.5027 | 0.8530 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0008 | 0.0002 | 0.0063 | 0.0016 | 0.0281 | 0.0131 | 0.0505 | 0.0215 | 0.0583 | 0.0156 | 0.0783 | 0.0233 | 0.7769 | 0.9246 | 0.0026 | 0.0102 | 0.0061 | 0.0051 | 0.0104 | 0.0255 | 0.0494 | 0.0561 | 0.1223 | 0.1378 | 0.1405 | 0.2168 | 0.1119 | 0.1173 | 0.1474 | 0.1505 | 0.4094 | 0.2806 | 0.0014 | 0.0034 | 0.0085 | 0.0263 | 0.0650 | 0.1026 | 0.0988 | 0.1173 | 0.5766 | 16 | 30 | 48 | 69 | 98 | 135 | 183 | 254 | 363 | 0.0144 | 28.33 | 5.755 | 0.4071 | 46815.8 | 20900000 | 11800000000 | 7940000000000 | 0.4493 | 0.1881 | 0.0467 | 0.0022 | 0.1642 | 0.0178 | 0.2921 | 0.0975 | 0.1659 | 0.1300 | 0.1366 | 0.1820 | 0.0977 | 0.1971 | 0.0467 | 0.1443 | 0.0285 | 0.1109 | 0.0216 | 0.1183 | 0.0000 | 0.0000 | 0.0016 | 0.0020 | 0.0024 | 0.0004 | 0.0199 | 0.0124 | 0.0749 | 0.0587 | 0.1204 | 0.0974 | 0.0863 | 0.0733 | 0.1178 | 0.1060 | 0.5768 | 0.6498 | 0.0004 | 0.0009 | 0.0008 | 0.0023 | 0.0046 | 0.0072 | 0.0347 | 0.0432 | 0.1206 | 0.1292 | 0.1583 | 0.1567 | 0.0946 | 0.1094 | 0.1389 | 0.1531 | 0.4472 | 0.3980 | 0.0010 | 0.0016 | 0.0035 | 0.0247 | 0.0958 | 0.1380 | 0.0986 | 0.1415 | 0.4954 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 609 | 251 | | 8474 | 32235 | 492.3 | 132.68 | 164.80 | 304.29 | 304 | 403 | 447 | 478 | 505 | 531 | 562 | 596 | 642 | 0.0423 | 1362 | 0.553 | 103.04 | 22.02 | 6 | 0.0340 | 288 | 0.0004 | 114.84 | 8.011 | 0.1304 | 259967.0 | 144000000 | 83000000000 | 49400000000000 | 0.3722 | 0.2591 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0037 | 0.0003 | 0.0143 | 0.0023 | 0.0499 | 0.0166 | 0.1100 | 0.0376 | 0.1112 | 0.0351 | 0.1452 | 0.0452 | 0.5648 | 0.8630 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0001 | 0.0025 | 0.0009 | 0.0146 | 0.0117 | 0.0325 | 0.0201 | 0.0307 | 0.0127 | 0.0470 | 0.0181 | 0.8723 | 0.9363 | 0.0022 | 0.0048 | 0.0077 | 0.0143 | 0.0132 | 0.0286 | 0.0548 | 0.0835 | 0.1064 | 0.2124 | 0.1656 | 0.1742 | 0.1162 | 0.1074 | 0.1436 | 0.1480 | 0.3904 | 0.2267 | 0.0004 | 0.0024 | 0.0034 | 0.0209 | 0.0482 | 0.0869 | 0.0897 | 0.1054 | 0.6428 | 11 | 14 | 16 | 19 | 25 | 41 | 97 | 243 | 543 | 0.1744 | 25.68 | 4.127 | 0.6433 | 119746.0 | 132000000 | 179000000000 | 274000000000000 | 0.3012 | 0.3397 | 0.0899 | 0.0040 | 0.2395 | 0.0218 | 0.2653 | 0.1374 | 0.1444 | 0.1732 | 0.1091 | 0.1910 | 0.0818 | 0.1739 | 0.0413 | 0.1102 | 0.0177 | 0.0848 | 0.0111 | 0.1039 | 0.0005 | 0.0004 | 0.0016 | 0.0005 | 0.0018 | 0.0022 | 0.0158 | 0.0127 | 0.0501 | 0.0477 | 0.0704 | 0.0633 | 0.0461 | 0.0432 | 0.0696 | 0.0655 | 0.7443 | 0.7646 | 0.0003 | 0.0003 | 0.0003 | 0.0026 | 0.0043 | 0.0048 | 0.0182 | 0.0201 | 0.0595 | 0.0574 | 0.0778 | 0.0868 | 0.0553 | 0.0575 | 0.0768 | 0.0805 | 0.7076 | 0.6901 | 0.0004 | 0.0001 | 0.0031 | 0.0149 | 0.0534 | 0.0785 | 0.0435 | 0.0762 | 0.7299 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 502 | 891 | | 697 | 2813 | 320.4 | 207.81 | 13.17 | 5.09 | 98 | 125 | 170 | 212 | 264 | 326 | 402 | 514 | 669 | 0.1337 | 376 | 1.160 | 26.25 | 8.00 | 2 | 0.0918 | 64 | 0.0019 | 99.20 | 6.369 | 0.1311 | 145754.0 | 81100000 | 50300000000 | 33200000000000 | 0.2968 | 0.3295 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0303 | 0.0000 | 0.0909 | 0.0036 | 0.2348 | 0.1155 | 0.2348 | 0.1769 | 0.2273 | 0.1227 | 0.1288 | 0.1444 | 0.0530 | 0.4368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0084 | 0.0022 | 0.0503 | 0.0508 | 0.0670 | 0.0640 | 0.0475 | 0.0375 | 0.0587 | 0.0486 | 0.7682 | 0.7969 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0133 | 0.0114 | 0.0487 | 0.0739 | 0.1062 | 0.0966 | 0.0442 | 0.0568 | 0.0752 | 0.0852 | 0.7124 | 0.6761 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0565 | 0.0919 | 0.0389 | 0.0671 | 0.7420 | 7 | 9 | 10 | 12 | 13 | 14 | 15 | 17 | 20 | 0.4201 | 0.26 | 1.281 | 0.8672 | 199.4 | 3414.53 | 65866.6 | 1430000 | 0.5670 | 0.1264 | 0.0375 | 0.0039 | 0.0586 | 0.0218 | 0.0980 | 0.0262 | 0.1548 | 0.0510 | 0.1951 | 0.0694 | 0.2070 | 0.0879 | 0.1712 | 0.1422 | 0.0678 | 0.2146 | 0.0101 | 0.3830 | 0.0136 | 0.0020 | 0.0172 | 0.0131 | 0.0183 | 0.0127 | 0.0365 | 0.0295 | 0.0662 | 0.0516 | 0.0986 | 0.0540 | 0.1377 | 0.0704 | 0.2165 | 0.1101 | 0.3954 | 0.6566 | 0.0545 | 0.0966 | 0.0703 | 0.0914 | 0.0812 | 0.0914 | 0.1018 | 0.1227 | 0.1115 | 0.1488 | 0.1236 | 0.1488 | 0.1164 | 0.1175 | 0.1794 | 0.1071 | 0.1612 | 0.0757 | 0.0122 | 0.0278 | 0.0523 | 0.0733 | 0.1025 | 0.1263 | 0.1514 | 0.1826 | 0.2716 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 267 | 437 | | 13592 | 31269 | 301.0 | 63.57 | 169.76 | 203.21 | 225 | 246 | 263 | 279 | 295 | 313 | 331 | 353 | 386 | 0.0450 | 1407 | 0.991 | 116.62 | 32.28 | 1 | 0.0211 | 287 | 0.0005 | 80.82 | 7.811 | 0.1322 | 94652.1 | 31000000 | 10600000000 | 3760000000000 | 0.4501 | 0.1998 | 0.0000 | 0.0000 | 0.0006 | 0.0002 | 0.0033 | 0.0002 | 0.0168 | 0.0009 | 0.0656 | 0.0133 | 0.1325 | 0.0320 | 0.1576 | 0.0360 | 0.1861 | 0.0572 | 0.4376 | 0.8603 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0001 | 0.0063 | 0.0004 | 0.0276 | 0.0084 | 0.0557 | 0.0188 | 0.0701 | 0.0154 | 0.0900 | 0.0249 | 0.7485 | 0.9321 | 0.0051 | 0.0171 | 0.0085 | 0.0240 | 0.0315 | 0.0719 | 0.0817 | 0.1199 | 0.1430 | 0.1747 | 0.1750 | 0.1695 | 0.1222 | 0.0925 | 0.1384 | 0.1318 | 0.2946 | 0.1986 | 0.0011 | 0.0024 | 0.0080 | 0.0318 | 0.0799 | 0.1235 | 0.1033 | 0.1392 | 0.5107 | 16 | 20 | 25 | 36 | 65 | 122 | 216 | 331 | 478 | 0.0295 | 54.42 | 5.957 | 0.4239 | 70109.3 | 38900000 | 25400000000 | 18600000000000 | 0.4659 | 0.1579 | 0.1220 | 0.0013 | 0.3239 | 0.0267 | 0.3147 | 0.2497 | 0.1092 | 0.2318 | 0.0683 | 0.1799 | 0.0358 | 0.1321 | 0.0147 | 0.0764 | 0.0073 | 0.0559 | 0.0041 | 0.0461 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0024 | 0.0013 | 0.0139 | 0.0099 | 0.0651 | 0.0580 | 0.1046 | 0.0910 | 0.0733 | 0.0686 | 0.1102 | 0.1024 | 0.6295 | 0.6682 | 0.0002 | 0.0003 | 0.0011 | 0.0020 | 0.0039 | 0.0045 | 0.0192 | 0.0256 | 0.0810 | 0.0887 | 0.1246 | 0.1262 | 0.0858 | 0.0977 | 0.1320 | 0.1374 | 0.5522 | 0.5175 | 0.0001 | 0.0012 | 0.0027 | 0.0147 | 0.0721 | 0.1162 | 0.0811 | 0.1158 | 0.5962 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 201 | 479 | | 6474 | 26300 | 321.0 | 57.21 | 100.08 | 124.51 | 249 | 270 | 287 | 303 | 318 | 334 | 351 | 372 | 398 | 0.0455 | 1196 | 1.134 | 99.86 | 37.59 | 2 | 0.0394 | 255 | 0.0006 | 73.06 | 7.553 | 0.1323 | 106297.0 | 36300000 | 12700000000 | 4580000000000 | 0.4555 | 0.1968 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0030 | 0.0002 | 0.0144 | 0.0008 | 0.0453 | 0.0123 | 0.1133 | 0.0261 | 0.1258 | 0.0247 | 0.1709 | 0.0467 | 0.5257 | 0.8892 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0002 | 0.0069 | 0.0003 | 0.0227 | 0.0113 | 0.0501 | 0.0206 | 0.0538 | 0.0157 | 0.0774 | 0.0244 | 0.7881 | 0.9275 | 0.0044 | 0.0805 | 0.0187 | 0.0575 | 0.0430 | 0.1839 | 0.0926 | 0.0920 | 0.1599 | 0.3103 | 0.1985 | 0.1379 | 0.1279 | 0.0460 | 0.1709 | 0.0805 | 0.1841 | 0.0115 | 0.0010 | 0.0025 | 0.0127 | 0.0290 | 0.0762 | 0.1275 | 0.1093 | 0.1393 | 0.5025 | 11 | 13 | 15 | 20 | 36 | 70 | 125 | 189 | 272 | 0.0574 | 15.56 | 4.832 | 0.5328 | 25517.2 | 9400000 | 4360000000 | 2400000000000 | 0.4719 | 0.1702 | 0.0761 | 0.0028 | 0.2702 | 0.0198 | 0.3311 | 0.1800 | 0.1322 | 0.2075 | 0.0992 | 0.2192 | 0.0530 | 0.1607 | 0.0236 | 0.0959 | 0.0105 | 0.0697 | 0.0042 | 0.0445 | 0.0001 | 0.0000 | 0.0007 | 0.0004 | 0.0009 | 0.0012 | 0.0101 | 0.0086 | 0.0551 | 0.0465 | 0.1067 | 0.0874 | 0.0756 | 0.0609 | 0.1039 | 0.0939 | 0.6470 | 0.7011 | 0.0004 | 0.0005 | 0.0005 | 0.0019 | 0.0037 | 0.0034 | 0.0152 | 0.0180 | 0.0736 | 0.0826 | 0.1416 | 0.1590 | 0.0968 | 0.1084 | 0.1346 | 0.1429 | 0.5337 | 0.4833 | 0.0006 | 0.0003 | 0.0023 | 0.0133 | 0.0603 | 0.1279 | 0.0841 | 0.1215 | 0.5898 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 380 | 183 | | 11039 | 18903 | 371.9 | 102.23 | 380.94 | 449.84 | 242 | 284 | 315 | 342 | 366 | 390 | 419 | 454 | 501 | 0.0627 | 1185 | 0.969 | 171.70 | 54.42 | 2 | 0.0400 | 442 | 0.0005 | 88.34 | 7.910 | 0.1324 | 148751.0 | 63700000 | 29100000000 | 14200000000000 | 0.4490 | 0.2026 | 0.0005 | 0.0000 | 0.0023 | 0.0001 | 0.0082 | 0.0004 | 0.0272 | 0.0029 | 0.0918 | 0.0254 | 0.1600 | 0.0644 | 0.1476 | 0.0628 | 0.1698 | 0.0955 | 0.3925 | 0.7484 | 0.0000 | 0.0000 | 0.0014 | 0.0001 | 0.0014 | 0.0002 | 0.0061 | 0.0012 | 0.0305 | 0.0163 | 0.0618 | 0.0383 | 0.0559 | 0.0283 | 0.0817 | 0.0492 | 0.7612 | 0.8664 | 0.0017 | 0.0049 | 0.0075 | 0.0233 | 0.0200 | 0.0331 | 0.0553 | 0.1129 | 0.1226 | 0.1755 | 0.1816 | 0.1718 | 0.1131 | 0.1055 | 0.1463 | 0.1313 | 0.3520 | 0.2417 | 0.0010 | 0.0019 | 0.0072 | 0.0234 | 0.0705 | 0.1244 | 0.0974 | 0.1322 | 0.5419 | 14 | 21 | 36 | 86 | 184 | 326 | 510 | 738 | 1059 | 0.0281 | 91.44 | 6.434 | 0.3906 | 347456.0 | 416000000 | 584000000000 | 919000000000000 | 0.5129 | 0.1516 | 0.0334 | 0.0012 | 0.1468 | 0.0085 | 0.2688 | 0.0832 | 0.1754 | 0.1376 | 0.1420 | 0.1939 | 0.1025 | 0.2057 | 0.0710 | 0.1331 | 0.0413 | 0.1056 | 0.0188 | 0.1313 | 0.0004 | 0.0001 | 0.0005 | 0.0002 | 0.0010 | 0.0015 | 0.0098 | 0.0078 | 0.0487 | 0.0404 | 0.0789 | 0.0691 | 0.0535 | 0.0457 | 0.0867 | 0.0737 | 0.7204 | 0.7615 | 0.0003 | 0.0002 | 0.0010 | 0.0016 | 0.0018 | 0.0031 | 0.0173 | 0.0236 | 0.0629 | 0.0721 | 0.1053 | 0.1168 | 0.0686 | 0.0778 | 0.1103 | 0.1157 | 0.6324 | 0.5891 | 0.0001 | 0.0003 | 0.0021 | 0.0129 | 0.0563 | 0.0923 | 0.0627 | 0.0991 | 0.6741 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 892 | 528 | | 438 | 4290 | 99.4 | 30.58 | 45.69 | 79.25 | 57 | 73 | 84 | 93 | 98 | 106 | 113 | 122 | 143 | 0.0991 | 425 | 0.186 | 244.68 | 30.23 | 3 | 2.7374 | 1199 | 0.0033 | 47.98 | 5.825 | 0.1324 | 10807.1 | 1270000 | 158000000 | 20800000000 | 0.3355 | 0.2955 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0091 | 0.0000 | 0.0727 | 0.0060 | 0.1182 | 0.0925 | 0.1318 | 0.0896 | 0.1591 | 0.0985 | 0.2045 | 0.1254 | 0.3045 | 0.5881 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0123 | 0.0026 | 0.0679 | 0.0596 | 0.0494 | 0.0570 | 0.0710 | 0.0440 | 0.0802 | 0.0648 | 0.7160 | 0.7720 | 0.0096 | 0.0000 | 0.0192 | 0.0000 | 0.0096 | 0.0392 | 0.0288 | 0.0196 | 0.1154 | 0.1961 | 0.1250 | 0.1765 | 0.0962 | 0.1176 | 0.1731 | 0.2745 | 0.4231 | 0.1765 | 0.0046 | 0.0092 | 0.0184 | 0.0276 | 0.0783 | 0.1014 | 0.1060 | 0.1382 | 0.5161 | 14 | 17 | 19 | 23 | 26 | 30 | 36 | 48 | 74 | 0.2037 | 1.21 | 2.394 | 0.8309 | 8367.0 | 4140000 | 2720000000 | 1970000000000 | 0.5493 | 0.1523 | 0.0193 | 0.0111 | 0.0456 | 0.0222 | 0.1298 | 0.0341 | 0.1333 | 0.0632 | 0.1754 | 0.1091 | 0.2140 | 0.1543 | 0.1386 | 0.1508 | 0.0930 | 0.1737 | 0.0509 | 0.2814 | 0.0072 | 0.0081 | 0.0087 | 0.0163 | 0.0223 | 0.0229 | 0.0405 | 0.0366 | 0.0692 | 0.0630 | 0.0922 | 0.0885 | 0.0978 | 0.0976 | 0.1065 | 0.1205 | 0.5556 | 0.5465 | 0.0029 | 0.0000 | 0.0116 | 0.0303 | 0.0305 | 0.0227 | 0.0349 | 0.0360 | 0.0799 | 0.0833 | 0.1105 | 0.1174 | 0.1017 | 0.0947 | 0.1366 | 0.1193 | 0.4913 | 0.4962 | 0.0022 | 0.0076 | 0.0174 | 0.0239 | 0.0827 | 0.0914 | 0.1012 | 0.1164 | 0.5571 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 601 | 686 | | 5758 | 17030 | 397.1 | 119.07 | 171.17 | 319.20 | 250 | 303 | 340 | 370 | 399 | 425 | 453 | 488 | 544 | 0.0574 | 978 | 0.568 | 60.00 | 7.07 | 2 | 0.0215 | 124 | 0.0005 | 97.80 | 7.776 | 0.1333 | 171856.0 | 79700000 | 39400000000 | 20600000000000 | 0.4079 | 0.2202 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0052 | 0.0000 | 0.0226 | 0.0031 | 0.0730 | 0.0266 | 0.1337 | 0.0477 | 0.1337 | 0.0521 | 0.1656 | 0.0726 | 0.4656 | 0.7979 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0063 | 0.0017 | 0.0208 | 0.0127 | 0.0441 | 0.0194 | 0.0425 | 0.0182 | 0.0645 | 0.0279 | 0.8192 | 0.9200 | 0.0023 | 0.0041 | 0.0045 | 0.0124 | 0.0076 | 0.0124 | 0.0507 | 0.0930 | 0.1067 | 0.1901 | 0.1490 | 0.1880 | 0.1256 | 0.1281 | 0.1392 | 0.1446 | 0.4145 | 0.2273 | 0.0010 | 0.0003 | 0.0021 | 0.0202 | 0.0473 | 0.0976 | 0.0836 | 0.1113 | 0.6366 | 5 | 7 | 8 | 10 | 13 | 22 | 88 | 294 | 628 | 0.1377 | 50.79 | 4.207 | 0.5597 | 131179.0 | 139000000 | 176000000000 | 254000000000000 | 0.5846 | 0.0863 | 0.0582 | 0.0017 | 0.2681 | 0.0401 | 0.2751 | 0.1775 | 0.1552 | 0.1783 | 0.1005 | 0.1997 | 0.0688 | 0.1869 | 0.0317 | 0.0896 | 0.0159 | 0.0631 | 0.0265 | 0.0631 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0020 | 0.0004 | 0.0061 | 0.0081 | 0.0517 | 0.0448 | 0.0808 | 0.0738 | 0.0520 | 0.0519 | 0.0773 | 0.0732 | 0.7302 | 0.7477 | 0.0002 | 0.0003 | 0.0012 | 0.0008 | 0.0025 | 0.0027 | 0.0132 | 0.0146 | 0.0518 | 0.0606 | 0.1006 | 0.1026 | 0.0595 | 0.0686 | 0.0907 | 0.0951 | 0.6801 | 0.6548 | 0.0000 | 0.0009 | 0.0028 | 0.0100 | 0.0510 | 0.0861 | 0.0591 | 0.0841 | 0.7059 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 121 | 590 | | 6826 | 22797 | 692.3 | 141.16 | 184.25 | 147.65 | 524 | 569 | 603 | 636 | 672 | 711 | 754 | 812 | 894 | 0.0504 | 1149 | 1.195 | 96.01 | 36.50 | 1 | 0.0355 | 242 | 0.0006 | 74.81 | 7.679 | 0.1333 | 499160.0 | 375000000 | 293000000000 | 238000000000000 | 0.4097 | 0.2333 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0033 | 0.0000 | 0.0134 | 0.0015 | 0.0541 | 0.0141 | 0.1179 | 0.0327 | 0.1221 | 0.0242 | 0.1447 | 0.0447 | 0.5439 | 0.8825 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0054 | 0.0001 | 0.0244 | 0.0100 | 0.0560 | 0.0208 | 0.0529 | 0.0091 | 0.0796 | 0.0171 | 0.7802 | 0.9428 | 0.0000 | 0.0210 | 0.0059 | 0.0385 | 0.0245 | 0.0559 | 0.0422 | 0.0594 | 0.1114 | 0.1713 | 0.1401 | 0.1608 | 0.1241 | 0.1014 | 0.1595 | 0.1399 | 0.3924 | 0.2517 | 0.0007 | 0.0033 | 0.0052 | 0.0244 | 0.0711 | 0.1157 | 0.0949 | 0.1252 | 0.5596 | 31 | 53 | 80 | 111 | 147 | 188 | 236 | 298 | 396 | 0.0053 | 17.90 | 6.140 | 0.3553 | 55747.2 | 22400000 | 11300000000 | 7040000000000 | 0.4802 | 0.1654 | 0.0189 | 0.0009 | 0.1045 | 0.0065 | 0.1943 | 0.0481 | 0.1712 | 0.0929 | 0.1772 | 0.1570 | 0.1568 | 0.1982 | 0.0804 | 0.1530 | 0.0592 | 0.1463 | 0.0375 | 0.1971 | 0.0006 | 0.0003 | 0.0018 | 0.0010 | 0.0062 | 0.0037 | 0.0214 | 0.0144 | 0.0636 | 0.0533 | 0.1041 | 0.0946 | 0.0826 | 0.0723 | 0.1081 | 0.1001 | 0.6117 | 0.6604 | 0.0021 | 0.0022 | 0.0055 | 0.0077 | 0.0141 | 0.0176 | 0.0366 | 0.0471 | 0.0854 | 0.0843 | 0.1155 | 0.1211 | 0.0905 | 0.0961 | 0.1101 | 0.1108 | 0.5402 | 0.5131 | 0.0011 | 0.0033 | 0.0088 | 0.0271 | 0.0757 | 0.1130 | 0.0967 | 0.1074 | 0.5670 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 329 | 607 | | 5771 | 20630 | 529.1 | 107.50 | 83.24 | 139.38 | 401 | 436 | 465 | 492 | 519 | 544 | 572 | 613 | 676 | 0.0490 | 1011 | 1.201 | 99.91 | 40.71 | 1 | 0.0452 | 261 | 0.0007 | 73.75 | 7.558 | 0.1339 | 291461.0 | 167000000 | 99900000000 | 62100000000000 | 0.4158 | 0.2294 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0031 | 0.0002 | 0.0148 | 0.0011 | 0.0604 | 0.0173 | 0.1177 | 0.0353 | 0.1405 | 0.0308 | 0.1599 | 0.0466 | 0.5026 | 0.8687 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0062 | 0.0000 | 0.0291 | 0.0118 | 0.0586 | 0.0242 | 0.0637 | 0.0139 | 0.0850 | 0.0235 | 0.7556 | 0.9266 | 0.0032 | 0.0079 | 0.0149 | 0.0277 | 0.0223 | 0.0316 | 0.0617 | 0.1067 | 0.1415 | 0.1225 | 0.1553 | 0.1858 | 0.0904 | 0.1225 | 0.1170 | 0.1304 | 0.3936 | 0.2648 | 0.0011 | 0.0023 | 0.0076 | 0.0345 | 0.0913 | 0.1330 | 0.1080 | 0.1258 | 0.4966 | 8 | 10 | 11 | 13 | 15 | 21 | 52 | 137 | 282 | 0.0906 | 17.39 | 4.254 | 0.5950 | 26353.8 | 12200000 | 6910000000 | 4480000000000 | 0.6077 | 0.0930 | 0.1055 | 0.0041 | 0.2829 | 0.0287 | 0.3598 | 0.1851 | 0.1526 | 0.2168 | 0.0596 | 0.2162 | 0.0335 | 0.1599 | 0.0037 | 0.0949 | 0.0025 | 0.0609 | 0.0000 | 0.0334 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0019 | 0.0016 | 0.0087 | 0.0077 | 0.0523 | 0.0454 | 0.0796 | 0.0732 | 0.0596 | 0.0497 | 0.0965 | 0.0851 | 0.7010 | 0.7371 | 0.0006 | 0.0002 | 0.0008 | 0.0018 | 0.0020 | 0.0042 | 0.0140 | 0.0178 | 0.0566 | 0.0567 | 0.1052 | 0.1144 | 0.0708 | 0.0696 | 0.1036 | 0.1054 | 0.6462 | 0.6299 | 0.0002 | 0.0004 | 0.0019 | 0.0113 | 0.0550 | 0.0902 | 0.0700 | 0.1005 | 0.6706 | ||
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 355 | 746 | | 5178 | 14618 | 327.7 | 65.14 | 129.72 | 168.91 | 250 | 272 | 289 | 304 | 321 | 339 | 359 | 383 | 416 | 0.0483 | 706 | 1.223 | 132.20 | 48.33 | 1 | 0.0624 | 323 | 0.0006 | 79.47 | 7.577 | 0.1347 | 111643.0 | 39500000 | 14500000000 | 5500000000000 | 0.4016 | 0.2477 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0020 | 0.0000 | 0.0124 | 0.0010 | 0.0615 | 0.0141 | 0.1154 | 0.0278 | 0.1391 | 0.0377 | 0.1708 | 0.0498 | 0.4976 | 0.8695 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0048 | 0.0006 | 0.0275 | 0.0103 | 0.0562 | 0.0177 | 0.0558 | 0.0168 | 0.0767 | 0.0242 | 0.7779 | 0.9305 | 0.0000 | 0.0057 | 0.0082 | 0.0341 | 0.0411 | 0.0625 | 0.0799 | 0.1591 | 0.1246 | 0.1932 | 0.1669 | 0.1648 | 0.1269 | 0.1193 | 0.1504 | 0.1307 | 0.3020 | 0.1307 | 0.0025 | 0.0038 | 0.0046 | 0.0302 | 0.0772 | 0.1234 | 0.1083 | 0.1318 | 0.5183 | 11 | 13 | 15 | 20 | 32 | 75 | 158 | 264 | 389 | 0.0486 | 32.17 | 5.262 | 0.4801 | 45355.6 | 21000000 | 11400000000 | 6870000000000 | 0.5030 | 0.1599 | 0.1206 | 0.0006 | 0.3330 | 0.0356 | 0.3146 | 0.2808 | 0.1079 | 0.2475 | 0.0769 | 0.1991 | 0.0321 | 0.1068 | 0.0115 | 0.0595 | 0.0023 | 0.0473 | 0.0011 | 0.0228 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0019 | 0.0009 | 0.0117 | 0.0095 | 0.0635 | 0.0521 | 0.0928 | 0.0937 | 0.0628 | 0.0577 | 0.1074 | 0.0968 | 0.6595 | 0.6891 | 0.0007 | 0.0007 | 0.0007 | 0.0015 | 0.0029 | 0.0020 | 0.0167 | 0.0162 | 0.0625 | 0.0729 | 0.1186 | 0.1226 | 0.0783 | 0.0896 | 0.1208 | 0.1300 | 0.5988 | 0.5646 | 0.0000 | 0.0002 | 0.0037 | 0.0165 | 0.0591 | 0.1021 | 0.0779 | 0.1118 | 0.6285 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 321 | 840 | | 426 | 368 | 95.5 | 47.70 | 697.86 | 488.70 | 32 | 42 | 60 | 77 | 96 | 112 | 127 | 143 | 162 | 0.4701 | 173 | 0.664 | 93.61 | 19.80 | 1 | 0.5915 | 252 | 0.0030 | 67.57 | 5.878 | 0.1356 | 11384.7 | 1540000 | 222000000 | 33700000000 | 0.2891 | 0.3236 | 0.0000 | 0.0000 | 0.0000 | 0.0052 | 0.1616 | 0.0000 | 0.1919 | 0.0155 | 0.2121 | 0.1503 | 0.1515 | 0.2591 | 0.2020 | 0.1295 | 0.0404 | 0.1969 | 0.0404 | 0.2435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0077 | 0.0032 | 0.0575 | 0.0583 | 0.0996 | 0.0841 | 0.0421 | 0.0388 | 0.0613 | 0.0680 | 0.7318 | 0.7476 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0062 | 0.0000 | 0.0247 | 0.0517 | 0.0802 | 0.0862 | 0.1049 | 0.1897 | 0.0988 | 0.1207 | 0.1420 | 0.1034 | 0.5432 | 0.4483 | 0.0000 | 0.0000 | 0.0000 | 0.0140 | 0.0698 | 0.0930 | 0.0512 | 0.0884 | 0.6837 | 135 | 270 | 399 | 510 | 616 | 717 | 852 | 1036 | 1456 | 0.0038 | 170.10 | 5.726 | 0.1849 | 725176.0 | 955000000 | 1470000000000 | 2.5E+15 | 0.4289 | 0.2015 | 0.0465 | 0.0000 | 0.1860 | 0.0120 | 0.2558 | 0.0663 | 0.1279 | 0.1205 | 0.1047 | 0.2651 | 0.1395 | 0.2108 | 0.0814 | 0.1566 | 0.0581 | 0.0904 | 0.0000 | 0.0783 | 0.0050 | 0.0000 | 0.0300 | 0.0000 | 0.0550 | 0.0405 | 0.0750 | 0.0526 | 0.1250 | 0.1579 | 0.1600 | 0.1741 | 0.1700 | 0.1660 | 0.1450 | 0.1296 | 0.2350 | 0.2794 | 0.0439 | 0.0000 | 0.0351 | 0.0000 | 0.0263 | 0.0864 | 0.1228 | 0.0864 | 0.1053 | 0.1605 | 0.2193 | 0.1235 | 0.0965 | 0.1111 | 0.0965 | 0.1358 | 0.2544 | 0.2963 | 0.0132 | 0.0395 | 0.0724 | 0.0921 | 0.1645 | 0.1579 | 0.1382 | 0.0921 | 0.2303 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 425 | 155 | | 10526 | 21020 | 318.4 | 61.96 | 206.32 | 250.19 | 242 | 266 | 284 | 299 | 314 | 330 | 347 | 369 | 404 | 0.0516 | 1084 | 1.093 | 105.19 | 36.12 | 1 | 0.0249 | 262 | 0.0006 | 81.62 | 7.746 | 0.1363 | 105224.0 | 36000000 | 12800000000 | 4660000000000 | 0.4431 | 0.2108 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0026 | 0.0000 | 0.0134 | 0.0015 | 0.0534 | 0.0127 | 0.1190 | 0.0291 | 0.1293 | 0.0329 | 0.1742 | 0.0536 | 0.5079 | 0.8701 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0007 | 0.0233 | 0.0087 | 0.0553 | 0.0181 | 0.0559 | 0.0145 | 0.0879 | 0.0257 | 0.7716 | 0.9324 | 0.0047 | 0.0280 | 0.0142 | 0.0592 | 0.0272 | 0.0592 | 0.0781 | 0.1526 | 0.1230 | 0.2087 | 0.1715 | 0.2150 | 0.1212 | 0.1277 | 0.1467 | 0.0779 | 0.3134 | 0.0717 | 0.0012 | 0.0020 | 0.0075 | 0.0315 | 0.0817 | 0.1365 | 0.1121 | 0.1303 | 0.4971 | 16 | 20 | 26 | 45 | 90 | 165 | 257 | 379 | 569 | 0.0265 | 51.36 | 6.104 | 0.4177 | 105162.0 | 74300000 | 63500000000 | 62100000000000 | 0.4677 | 0.1545 | 0.0348 | 0.0018 | 0.1515 | 0.0098 | 0.2413 | 0.0665 | 0.1600 | 0.1355 | 0.1658 | 0.1909 | 0.1109 | 0.1899 | 0.0702 | 0.1368 | 0.0428 | 0.1209 | 0.0227 | 0.1479 | 0.0001 | 0.0002 | 0.0006 | 0.0006 | 0.0021 | 0.0007 | 0.0075 | 0.0067 | 0.0513 | 0.0425 | 0.0842 | 0.0699 | 0.0615 | 0.0534 | 0.0927 | 0.0778 | 0.7001 | 0.7481 | 0.0000 | 0.0002 | 0.0017 | 0.0024 | 0.0040 | 0.0065 | 0.0161 | 0.0168 | 0.0672 | 0.0746 | 0.1113 | 0.1207 | 0.0727 | 0.0793 | 0.1113 | 0.1116 | 0.6157 | 0.5879 | 0.0003 | 0.0009 | 0.0029 | 0.0128 | 0.0565 | 0.0983 | 0.0684 | 0.1010 | 0.6588 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 306 | 790 | | 10808 | 25449 | 298.9 | 63.05 | 184.36 | 193.71 | 220 | 246 | 264 | 280 | 296 | 313 | 331 | 352 | 380 | 0.0474 | 1207 | 1.110 | 105.26 | 43.74 | 1 | 0.0265 | 286 | 0.0005 | 81.12 | 7.748 | 0.1366 | 93311.6 | 30300000 | 10200000000 | 3580000000000 | 0.4573 | 0.1982 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0044 | 0.0004 | 0.0195 | 0.0011 | 0.0692 | 0.0138 | 0.1340 | 0.0324 | 0.1426 | 0.0358 | 0.1632 | 0.0476 | 0.4660 | 0.8689 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0002 | 0.0056 | 0.0003 | 0.0270 | 0.0101 | 0.0603 | 0.0229 | 0.0590 | 0.0172 | 0.0778 | 0.0237 | 0.7694 | 0.9257 | 0.0068 | 0.0176 | 0.0084 | 0.0352 | 0.0340 | 0.0557 | 0.0748 | 0.1701 | 0.1511 | 0.1935 | 0.1730 | 0.1437 | 0.1270 | 0.1114 | 0.1505 | 0.1202 | 0.2744 | 0.1525 | 0.0002 | 0.0013 | 0.0071 | 0.0283 | 0.0777 | 0.1375 | 0.1086 | 0.1338 | 0.5055 | 13 | 17 | 24 | 51 | 111 | 191 | 262 | 346 | 463 | 0.0242 | 36.87 | 6.001 | 0.4043 | 71512.1 | 35800000 | 20900000000 | 13700000000000 | 0.4160 | 0.2115 | 0.0758 | 0.0028 | 0.2291 | 0.0178 | 0.2929 | 0.1362 | 0.1723 | 0.1731 | 0.1102 | 0.2094 | 0.0642 | 0.1810 | 0.0336 | 0.1219 | 0.0141 | 0.0926 | 0.0079 | 0.0652 | 0.0001 | 0.0002 | 0.0002 | 0.0002 | 0.0011 | 0.0009 | 0.0083 | 0.0060 | 0.0510 | 0.0445 | 0.0925 | 0.0721 | 0.0732 | 0.0598 | 0.1091 | 0.0919 | 0.6645 | 0.7243 | 0.0003 | 0.0004 | 0.0012 | 0.0030 | 0.0038 | 0.0091 | 0.0196 | 0.0268 | 0.0753 | 0.0878 | 0.1241 | 0.1477 | 0.1070 | 0.1093 | 0.1439 | 0.1482 | 0.5247 | 0.4678 | 0.0002 | 0.0006 | 0.0017 | 0.0130 | 0.0634 | 0.1073 | 0.0854 | 0.1313 | 0.5971 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 919 | 384 | | 3864 | 10644 | 549.9 | 111.66 | 119.69 | 118.07 | 401 | 445 | 482 | 515 | 547 | 581 | 614 | 651 | 699 | 0.0750 | 798 | 1.029 | 90.48 | 35.85 | 1 | 0.0663 | 256 | 0.0007 | 70.72 | 7.491 | 0.1370 | 314839.0 | 187000000 | 115000000000 | 72500000000000 | 0.4423 | 0.2000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0000 | 0.0131 | 0.0027 | 0.0668 | 0.0158 | 0.1439 | 0.0363 | 0.1447 | 0.0328 | 0.1681 | 0.0507 | 0.4596 | 0.8617 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0051 | 0.0021 | 0.0277 | 0.0136 | 0.0621 | 0.0288 | 0.0535 | 0.0207 | 0.0701 | 0.0298 | 0.7804 | 0.9050 | 0.0029 | 0.0519 | 0.0114 | 0.0390 | 0.0157 | 0.0390 | 0.0672 | 0.1818 | 0.1502 | 0.2338 | 0.1788 | 0.1948 | 0.1288 | 0.1169 | 0.1431 | 0.0519 | 0.3019 | 0.0909 | 0.0000 | 0.0010 | 0.0037 | 0.0199 | 0.0659 | 0.1141 | 0.0795 | 0.1141 | 0.6018 | 11 | 15 | 23 | 44 | 81 | 122 | 165 | 219 | 293 | 0.0192 | 16.46 | 5.675 | 0.4317 | 28266.0 | 8580000 | 3000000000 | 1160000000000 | 0.4622 | 0.1810 | 0.0320 | 0.0021 | 0.1652 | 0.0111 | 0.2654 | 0.0848 | 0.1446 | 0.1330 | 0.1611 | 0.2072 | 0.1002 | 0.1734 | 0.0666 | 0.1199 | 0.0411 | 0.1273 | 0.0238 | 0.1413 | 0.0004 | 0.0004 | 0.0002 | 0.0004 | 0.0026 | 0.0020 | 0.0100 | 0.0065 | 0.0573 | 0.0464 | 0.0915 | 0.0770 | 0.0713 | 0.0525 | 0.1045 | 0.0919 | 0.6622 | 0.7230 | 0.0003 | 0.0006 | 0.0019 | 0.0016 | 0.0054 | 0.0048 | 0.0200 | 0.0279 | 0.0764 | 0.0901 | 0.1300 | 0.1487 | 0.0978 | 0.0983 | 0.1230 | 0.1376 | 0.5451 | 0.4903 | 0.0005 | 0.0016 | 0.0023 | 0.0137 | 0.0615 | 0.1121 | 0.0896 | 0.1246 | 0.5942 | ||
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 213 | 896 | | 3746 | 14440 | 324.0 | 67.68 | 163.52 | 174.35 | 235 | 267 | 288 | 305 | 322 | 340 | 359 | 382 | 414 | 0.0614 | 886 | 1.026 | 90.35 | 31.58 | 1 | 0.0670 | 251 | 0.0007 | 89.85 | 7.502 | 0.1378 | 109544.0 | 38500000 | 14000000000 | 5270000000000 | 0.4313 | 0.2081 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0008 | 0.0143 | 0.0014 | 0.0573 | 0.0161 | 0.1297 | 0.0417 | 0.1481 | 0.0296 | 0.1661 | 0.0735 | 0.4822 | 0.8369 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0052 | 0.0014 | 0.0223 | 0.0128 | 0.0419 | 0.0312 | 0.0461 | 0.0115 | 0.0652 | 0.0325 | 0.8187 | 0.9101 | 0.0015 | 0.0741 | 0.0092 | 0.0556 | 0.0382 | 0.0926 | 0.0947 | 0.1667 | 0.1740 | 0.1852 | 0.1969 | 0.1481 | 0.1191 | 0.0926 | 0.1481 | 0.1111 | 0.2183 | 0.0741 | 0.0000 | 0.0005 | 0.0054 | 0.0264 | 0.0696 | 0.1192 | 0.1154 | 0.1472 | 0.5162 | 13 | 17 | 27 | 55 | 99 | 150 | 212 | 304 | 427 | 0.0207 | 22.64 | 5.797 | 0.4177 | 57133.8 | 26400000 | 14400000000 | 8750000000000 | 0.5240 | 0.1275 | 0.0365 | 0.0012 | 0.1204 | 0.0053 | 0.1762 | 0.0439 | 0.2018 | 0.1082 | 0.1883 | 0.1766 | 0.1249 | 0.1778 | 0.0762 | 0.1466 | 0.0532 | 0.1487 | 0.0224 | 0.1917 | 0.0006 | 0.0004 | 0.0018 | 0.0006 | 0.0042 | 0.0024 | 0.0165 | 0.0138 | 0.0564 | 0.0447 | 0.0762 | 0.0656 | 0.0665 | 0.0531 | 0.0911 | 0.0798 | 0.6869 | 0.7397 | 0.0013 | 0.0013 | 0.0019 | 0.0043 | 0.0055 | 0.0080 | 0.0249 | 0.0268 | 0.0675 | 0.0771 | 0.0949 | 0.1009 | 0.0777 | 0.0746 | 0.0971 | 0.0949 | 0.6292 | 0.6123 | 0.0004 | 0.0022 | 0.0050 | 0.0187 | 0.0604 | 0.0872 | 0.0731 | 0.1006 | 0.6523 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 972 | 297 | | 4771 | 7211 | 303.5 | 65.31 | 240.93 | 226.65 | 218 | 246 | 266 | 285 | 301 | 318 | 336 | 359 | 393 | 0.1144 | 825 | 0.746 | 99.85 | 18.25 | 1 | 0.0470 | 224 | 0.0006 | 79.54 | 7.546 | 0.1380 | 96372.4 | 31900000 | 11000000000 | 3900000000000 | 0.4166 | 0.2336 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0180 | 0.0018 | 0.0709 | 0.0195 | 0.1275 | 0.0424 | 0.1468 | 0.0462 | 0.1774 | 0.0735 | 0.4551 | 0.8167 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0004 | 0.0315 | 0.0150 | 0.0601 | 0.0295 | 0.0668 | 0.0242 | 0.0840 | 0.0406 | 0.7492 | 0.8903 | 0.0069 | 0.0237 | 0.0183 | 0.0473 | 0.0171 | 0.1065 | 0.0674 | 0.1598 | 0.1063 | 0.2189 | 0.1337 | 0.1479 | 0.1029 | 0.0651 | 0.1349 | 0.0947 | 0.4126 | 0.1361 | 0.0004 | 0.0004 | 0.0056 | 0.0299 | 0.0837 | 0.1205 | 0.1008 | 0.1166 | 0.5421 | 18 | 24 | 51 | 105 | 176 | 253 | 344 | 445 | 581 | 0.0200 | 42.53 | 6.319 | 0.3498 | 109411.0 | 62100000 | 40100000000 | 28400000000000 | 0.5244 | 0.1362 | 0.0141 | 0.0041 | 0.1315 | 0.0113 | 0.1984 | 0.0504 | 0.1737 | 0.0989 | 0.2007 | 0.1819 | 0.1080 | 0.2044 | 0.0869 | 0.1380 | 0.0552 | 0.1220 | 0.0317 | 0.1890 | 0.0003 | 0.0000 | 0.0020 | 0.0008 | 0.0014 | 0.0013 | 0.0098 | 0.0072 | 0.0571 | 0.0424 | 0.0704 | 0.0721 | 0.0637 | 0.0570 | 0.0947 | 0.0816 | 0.7006 | 0.7377 | 0.0004 | 0.0005 | 0.0023 | 0.0027 | 0.0104 | 0.0068 | 0.0154 | 0.0263 | 0.0677 | 0.0693 | 0.0903 | 0.1014 | 0.0765 | 0.0928 | 0.1107 | 0.1241 | 0.6263 | 0.5761 | 0.0003 | 0.0027 | 0.0020 | 0.0140 | 0.0578 | 0.0905 | 0.0708 | 0.1002 | 0.6617 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 729 | 312 | | 7306 | 11974 | 613.3 | 129.28 | 138.56 | 260.97 | 460 | 513 | 546 | 576 | 604 | 631 | 663 | 705 | 779 | 0.0833 | 997 | 1.173 | 110.11 | 34.67 | 1 | 0.0356 | 260 | 0.0006 | 91.47 | 7.747 | 0.1387 | 392795.0 | 263000000 | 183000000000 | 133000000000000 | 0.4412 | 0.2054 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0004 | 0.0084 | 0.0022 | 0.0416 | 0.0166 | 0.0910 | 0.0363 | 0.1054 | 0.0298 | 0.1371 | 0.0406 | 0.6140 | 0.8741 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0004 | 0.0024 | 0.0010 | 0.0180 | 0.0122 | 0.0418 | 0.0199 | 0.0422 | 0.0119 | 0.0634 | 0.0208 | 0.8310 | 0.9338 | 0.0046 | 0.0000 | 0.0092 | 0.0029 | 0.0295 | 0.0146 | 0.0867 | 0.1108 | 0.0941 | 0.1837 | 0.1614 | 0.2157 | 0.1144 | 0.1224 | 0.1153 | 0.1079 | 0.3847 | 0.2420 | 0.0015 | 0.0056 | 0.0082 | 0.0316 | 0.0647 | 0.1109 | 0.0989 | 0.1229 | 0.5559 | 6 | 8 | 9 | 13 | 22 | 47 | 98 | 198 | 434 | 0.0993 | 31.78 | 4.313 | 0.5808 | 87298.6 | 89300000 | 118000000000 | 185000000000000 | 0.4711 | 0.1719 | 0.0442 | 0.0014 | 0.1509 | 0.0196 | 0.2302 | 0.0825 | 0.2088 | 0.0965 | 0.1814 | 0.1972 | 0.0838 | 0.1930 | 0.0427 | 0.1343 | 0.0381 | 0.1273 | 0.0198 | 0.1483 | 0.0003 | 0.0005 | 0.0009 | 0.0005 | 0.0009 | 0.0018 | 0.0089 | 0.0096 | 0.0546 | 0.0480 | 0.1005 | 0.0828 | 0.0650 | 0.0568 | 0.0942 | 0.0835 | 0.6747 | 0.7164 | 0.0004 | 0.0004 | 0.0004 | 0.0012 | 0.0022 | 0.0008 | 0.0115 | 0.0144 | 0.0749 | 0.0804 | 0.1197 | 0.1267 | 0.0782 | 0.0776 | 0.1019 | 0.1110 | 0.6108 | 0.5875 | 0.0000 | 0.0003 | 0.0013 | 0.0127 | 0.0586 | 0.1195 | 0.0696 | 0.0917 | 0.6463 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 802 | 490 | | 8351 | 22610 | 575.7 | 122.92 | 67.00 | 140.53 | 447 | 481 | 507 | 530 | 554 | 578 | 610 | 654 | 726 | 0.0503 | 1138 | 0.892 | 99.02 | 25.02 | 1 | 0.0290 | 242 | 0.0006 | 85.09 | 7.659 | 0.1388 | 346489.0 | 219000000 | 147000000000 | 104000000000000 | 0.4366 | 0.2123 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0000 | 0.0107 | 0.0008 | 0.0464 | 0.0130 | 0.0968 | 0.0349 | 0.1084 | 0.0240 | 0.1476 | 0.0372 | 0.5879 | 0.8901 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0054 | 0.0000 | 0.0254 | 0.0090 | 0.0547 | 0.0192 | 0.0514 | 0.0107 | 0.0823 | 0.0199 | 0.7799 | 0.9412 | 0.0017 | 0.0022 | 0.0111 | 0.0066 | 0.0085 | 0.0087 | 0.0752 | 0.0502 | 0.1265 | 0.1397 | 0.1282 | 0.1790 | 0.0966 | 0.0830 | 0.1154 | 0.1397 | 0.4368 | 0.3908 | 0.0018 | 0.0062 | 0.0117 | 0.0486 | 0.0847 | 0.1260 | 0.0923 | 0.1116 | 0.5173 | 5 | 6 | 7 | 8 | 9 | 11 | 17 | 73 | 234 | 0.2107 | 10.92 | 3.086 | 0.6429 | 24238.2 | 13000000 | 8460000000 | 6260000000000 | 0.4231 | 0.2043 | 0.0750 | 0.0052 | 0.2339 | 0.0353 | 0.2519 | 0.1576 | 0.1589 | 0.1532 | 0.1364 | 0.2054 | 0.0885 | 0.1760 | 0.0390 | 0.1105 | 0.0150 | 0.0913 | 0.0015 | 0.0655 | 0.0000 | 0.0002 | 0.0004 | 0.0006 | 0.0016 | 0.0006 | 0.0084 | 0.0107 | 0.0408 | 0.0369 | 0.0753 | 0.0625 | 0.0404 | 0.0411 | 0.0677 | 0.0705 | 0.7654 | 0.7769 | 0.0002 | 0.0000 | 0.0009 | 0.0005 | 0.0016 | 0.0032 | 0.0125 | 0.0133 | 0.0519 | 0.0529 | 0.0775 | 0.0940 | 0.0542 | 0.0529 | 0.0860 | 0.0876 | 0.7152 | 0.6955 | 0.0002 | 0.0013 | 0.0024 | 0.0124 | 0.0425 | 0.0726 | 0.0494 | 0.0774 | 0.7419 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 659 | 864 | | 9157 | 12600 | 572.9 | 114.09 | 133.84 | 114.82 | 435 | 475 | 505 | 534 | 563 | 594 | 628 | 666 | 723 | 0.0900 | 1134 | 1.199 | 96.51 | 40.61 | 1 | 0.0284 | 260 | 0.0005 | 84.01 | 7.780 | 0.1396 | 341248.0 | 211000000 | 136000000000 | 90100000000000 | 0.4173 | 0.2328 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0013 | 0.0001 | 0.0084 | 0.0014 | 0.0529 | 0.0133 | 0.1231 | 0.0303 | 0.1329 | 0.0280 | 0.1634 | 0.0394 | 0.5172 | 0.8876 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0045 | 0.0001 | 0.0267 | 0.0098 | 0.0603 | 0.0210 | 0.0668 | 0.0155 | 0.0864 | 0.0211 | 0.7545 | 0.9324 | 0.0022 | 0.0060 | 0.0129 | 0.0121 | 0.0237 | 0.0423 | 0.0760 | 0.0755 | 0.1097 | 0.1631 | 0.1627 | 0.1450 | 0.0968 | 0.1329 | 0.1168 | 0.1541 | 0.3993 | 0.2689 | 0.0000 | 0.0012 | 0.0046 | 0.0244 | 0.0835 | 0.1249 | 0.1047 | 0.1165 | 0.5403 | 14 | 26 | 50 | 78 | 106 | 138 | 176 | 224 | 297 | 0.0077 | 28.76 | 6.275 | 0.3483 | 31096.2 | 9370000 | 3320000000 | 1310000000000 | 0.6019 | 0.1025 | 0.0320 | 0.0017 | 0.1338 | 0.0087 | 0.2500 | 0.0546 | 0.1658 | 0.1008 | 0.1684 | 0.1801 | 0.1271 | 0.1957 | 0.0646 | 0.1465 | 0.0413 | 0.1349 | 0.0170 | 0.1769 | 0.0005 | 0.0004 | 0.0008 | 0.0005 | 0.0031 | 0.0019 | 0.0161 | 0.0096 | 0.0663 | 0.0503 | 0.1259 | 0.0945 | 0.0830 | 0.0727 | 0.1216 | 0.1056 | 0.5828 | 0.6645 | 0.0009 | 0.0012 | 0.0042 | 0.0084 | 0.0093 | 0.0160 | 0.0313 | 0.0389 | 0.1011 | 0.1062 | 0.1497 | 0.1596 | 0.1025 | 0.1120 | 0.1383 | 0.1416 | 0.4626 | 0.4161 | 0.0008 | 0.0029 | 0.0060 | 0.0229 | 0.0836 | 0.1434 | 0.0928 | 0.1261 | 0.5216 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 401 | 465 | | 5688 | 21468 | 395.0 | 83.99 | 124.18 | 239.02 | 290 | 326 | 352 | 373 | 392 | 410 | 430 | 457 | 504 | 0.0522 | 1120 | 1.175 | 146.10 | 54.92 | 1 | 0.0647 | 368 | 0.0007 | 85.77 | 7.563 | 0.1400 | 163082.0 | 70200000 | 31500000000 | 14700000000000 | 0.4503 | 0.2076 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0036 | 0.0000 | 0.0145 | 0.0009 | 0.0614 | 0.0220 | 0.1338 | 0.0403 | 0.1196 | 0.0438 | 0.1527 | 0.0645 | 0.5131 | 0.8284 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0036 | 0.0004 | 0.0302 | 0.0151 | 0.0598 | 0.0258 | 0.0550 | 0.0211 | 0.0858 | 0.0337 | 0.7648 | 0.9040 | 0.0011 | 0.0168 | 0.0078 | 0.0294 | 0.0343 | 0.0546 | 0.0676 | 0.1723 | 0.1495 | 0.1765 | 0.2137 | 0.2185 | 0.0952 | 0.0840 | 0.1384 | 0.0840 | 0.2924 | 0.1639 | 0.0018 | 0.0025 | 0.0094 | 0.0305 | 0.0864 | 0.1409 | 0.1097 | 0.1543 | 0.4644 | 7 | 8 | 9 | 11 | 13 | 19 | 59 | 166 | 460 | 0.2326 | 28.31 | 3.763 | 0.6555 | 72548.9 | 59000000 | 55500000000 | 57500000000000 | 0.4057 | 0.2332 | 0.0627 | 0.0034 | 0.2304 | 0.0282 | 0.2413 | 0.1477 | 0.1242 | 0.1167 | 0.1363 | 0.1635 | 0.0893 | 0.1860 | 0.0555 | 0.1037 | 0.0483 | 0.1020 | 0.0121 | 0.1488 | 0.0000 | 0.0002 | 0.0002 | 0.0000 | 0.0007 | 0.0015 | 0.0069 | 0.0057 | 0.0502 | 0.0393 | 0.0700 | 0.0667 | 0.0470 | 0.0434 | 0.0722 | 0.0667 | 0.7528 | 0.7766 | 0.0000 | 0.0002 | 0.0007 | 0.0007 | 0.0015 | 0.0021 | 0.0071 | 0.0088 | 0.0563 | 0.0601 | 0.0801 | 0.0852 | 0.0541 | 0.0560 | 0.0781 | 0.0805 | 0.7221 | 0.7063 | 0.0000 | 0.0000 | 0.0024 | 0.0088 | 0.0529 | 0.0768 | 0.0489 | 0.0729 | 0.7373 |