High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 274 | 724 | | 833 | 13982 | 37.7 | 9.22 | 181.15 | 216.84 | 28 | 30 | 32 | 34 | 36 | 38 | 40 | 44 | 50 | 0.0473 | 662 | 1.199 | 23.54 | 8.94 | 3 | 0.0732 | 61 | 0.0229 | 2.86 | 4.160 | 0.4919 | 1505.4 | 64089 | 2920000 | 142000000 | 0.4024 | 0.2135 | 0.0039 | 0.0000 | 0.0197 | 0.0000 | 0.0197 | 0.0000 | 0.0907 | 0.0156 | 0.1243 | 0.0650 | 0.1460 | 0.0728 | 0.1913 | 0.1027 | 0.2012 | 0.1352 | 0.2032 | 0.6086 | 0.0031 | 0.0000 | 0.0108 | 0.0000 | 0.0154 | 0.0000 | 0.0555 | 0.0132 | 0.0709 | 0.0505 | 0.0755 | 0.0457 | 0.1248 | 0.0721 | 0.1171 | 0.0805 | 0.5270 | 0.7380 | 0.0141 | 0.0317 | 0.0070 | 0.0317 | 0.0211 | 0.0317 | 0.0845 | 0.0794 | 0.1268 | 0.1746 | 0.1479 | 0.1587 | 0.0775 | 0.1429 | 0.1831 | 0.1111 | 0.3380 | 0.2381 | 0.0089 | 0.0417 | 0.0357 | 0.0774 | 0.0923 | 0.1220 | 0.1042 | 0.1399 | 0.3780 | 13 | 15 | 18 | 25 | 72 | 155 | 247 | 356 | 505 | 0.1047 | 25.13 | 4.988 | 0.5234 | 79833.1 | 46100000 | 31400000000 | 24300000000000 | 0.5786 | 0.1133 | 0.0295 | 0.0009 | 0.1412 | 0.0151 | 0.2513 | 0.0722 | 0.1854 | 0.1324 | 0.1750 | 0.2019 | 0.1161 | 0.2027 | 0.0537 | 0.1479 | 0.0286 | 0.1209 | 0.0191 | 0.1062 | 0.0005 | 0.0000 | 0.0021 | 0.0008 | 0.0031 | 0.0022 | 0.0102 | 0.0085 | 0.0401 | 0.0383 | 0.0610 | 0.0504 | 0.0571 | 0.0510 | 0.0875 | 0.0745 | 0.7384 | 0.7744 | 0.0004 | 0.0002 | 0.0013 | 0.0015 | 0.0054 | 0.0051 | 0.0173 | 0.0245 | 0.0542 | 0.0646 | 0.0886 | 0.0970 | 0.0864 | 0.1030 | 0.1156 | 0.1191 | 0.6309 | 0.5849 | 0.0004 | 0.0035 | 0.0025 | 0.0146 | 0.0434 | 0.0766 | 0.0726 | 0.0991 | 0.6873 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 607 | 425 | | 710 | 2523 | 137.3 | 19.50 | 92.60 | 84.78 | 108 | 118 | 127 | 136 | 142 | 146 | 151 | 155 | 160 | 0.1550 | 391 | 0.898 | 77.52 | 25.50 | 1 | 0.3000 | 213 | 0.0194 | 2.48 | 4.222 | 0.5165 | 19229.6 | 2740000 | 397000000 | 58100000000 | 0.3917 | 0.2405 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0028 | 0.0547 | 0.0310 | 0.0547 | 0.0648 | 0.0813 | 0.0254 | 0.1360 | 0.0394 | 0.6617 | 0.8366 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0111 | 0.0028 | 0.0446 | 0.0310 | 0.0350 | 0.0648 | 0.0398 | 0.0254 | 0.0653 | 0.0394 | 0.8041 | 0.8366 | 0.1200 | 0.0000 | 0.2000 | 0.0000 | 0.3200 | 0.0000 | 0.0800 | 0.0000 | 0.2000 | 0.0000 | 0.0400 | 0.0000 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0290 | 0.0338 | 0.0531 | 0.0628 | 0.0773 | 0.7440 | 21 | 29 | 40 | 53 | 69 | 84 | 105 | 131 | 195 | 0.0217 | 5.49 | 4.593 | 0.5505 | 15759.1 | 4090000 | 1360000000 | 524000000000 | 0.5327 | 0.1397 | 0.0216 | 0.0021 | 0.0747 | 0.0164 | 0.0943 | 0.0472 | 0.1179 | 0.0626 | 0.1473 | 0.1067 | 0.1866 | 0.1456 | 0.1218 | 0.1292 | 0.1257 | 0.1518 | 0.1100 | 0.3385 | 0.0000 | 0.0014 | 0.0085 | 0.0041 | 0.0136 | 0.0135 | 0.0298 | 0.0230 | 0.0562 | 0.0594 | 0.1285 | 0.0939 | 0.0809 | 0.0689 | 0.1260 | 0.1060 | 0.5566 | 0.6300 | 0.0030 | 0.0099 | 0.0120 | 0.0059 | 0.0150 | 0.0198 | 0.0435 | 0.0435 | 0.0901 | 0.1087 | 0.1667 | 0.1601 | 0.0901 | 0.1186 | 0.1396 | 0.1719 | 0.4399 | 0.3617 | 0.0056 | 0.0134 | 0.0134 | 0.0335 | 0.0838 | 0.1173 | 0.1039 | 0.1363 | 0.4927 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 603 | 882 | | 1319 | 7737 | 66.4 | 71.59 | 51.64 | 108.03 | 33 | 34 | 36 | 37 | 38 | 40 | 42 | 54 | 179 | 0.0778 | 602 | 1.235 | 41.48 | 16.64 | 4 | 0.0819 | 108 | 0.0362 | 35.18 | 4.239 | 0.5039 | 9528.0 | 2260000 | 632000000 | 189000000000 | 0.3313 | 0.2814 | 0.0000 | 0.0369 | 0.0984 | 0.0938 | 0.3770 | 0.0966 | 0.2295 | 0.0966 | 0.2623 | 0.0909 | 0.0328 | 0.1790 | 0.0000 | 0.1932 | 0.0000 | 0.1364 | 0.0000 | 0.0767 | 0.0000 | 0.0236 | 0.0036 | 0.0599 | 0.0036 | 0.0617 | 0.0073 | 0.0617 | 0.0584 | 0.0399 | 0.0730 | 0.0690 | 0.0474 | 0.0853 | 0.0766 | 0.0853 | 0.7299 | 0.5136 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0094 | 0.0101 | 0.0657 | 0.0653 | 0.0892 | 0.1005 | 0.0469 | 0.0503 | 0.0892 | 0.0804 | 0.6995 | 0.6935 | 0.0000 | 0.0000 | 0.0000 | 0.0170 | 0.0468 | 0.0979 | 0.0511 | 0.0638 | 0.7234 | 9 | 10 | 11 | 12 | 13 | 15 | 17 | 26 | 172 | 0.2813 | 8.15 | 2.652 | 0.7496 | 14334.9 | 6050000 | 2920000000 | 1530000000000 | 0.6889 | 0.0590 | 0.0938 | 0.0063 | 0.2313 | 0.0472 | 0.2375 | 0.1824 | 0.1813 | 0.1981 | 0.1000 | 0.2390 | 0.0938 | 0.1447 | 0.0250 | 0.0755 | 0.0313 | 0.0503 | 0.0063 | 0.0566 | 0.0000 | 0.0014 | 0.0008 | 0.0007 | 0.0031 | 0.0021 | 0.0178 | 0.0192 | 0.0666 | 0.0655 | 0.0860 | 0.0734 | 0.0713 | 0.0734 | 0.0953 | 0.0962 | 0.6592 | 0.6681 | 0.0000 | 0.0000 | 0.0009 | 0.0018 | 0.0035 | 0.0018 | 0.0221 | 0.0230 | 0.0716 | 0.0718 | 0.0902 | 0.0948 | 0.0875 | 0.0902 | 0.1043 | 0.0976 | 0.6198 | 0.6188 | 0.0008 | 0.0000 | 0.0017 | 0.0215 | 0.0710 | 0.0834 | 0.0859 | 0.0983 | 0.6375 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 559 | 386 | | 734 | 10113 | 39.1 | 16.71 | 545.35 | 386.84 | 28 | 29 | 30 | 31 | 32 | 34 | 37 | 45 | 64 | 0.0518 | 524 | 0.593 | 209.07 | 60.01 | 2 | 0.9973 | 732 | 0.0308 | 4.90 | 4.259 | 0.5054 | 1809.2 | 103002 | 7120000 | 567000000 | 0.4029 | 0.2328 | 0.0252 | 0.0000 | 0.0540 | 0.0000 | 0.0755 | 0.0000 | 0.1295 | 0.0174 | 0.1403 | 0.0616 | 0.1799 | 0.0585 | 0.1403 | 0.0932 | 0.1475 | 0.0853 | 0.1079 | 0.6840 | 0.0170 | 0.0000 | 0.0365 | 0.0000 | 0.0462 | 0.0000 | 0.0754 | 0.0136 | 0.0730 | 0.0409 | 0.0900 | 0.0368 | 0.0681 | 0.0587 | 0.1095 | 0.0559 | 0.4842 | 0.7940 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0376 | 0.0200 | 0.0752 | 0.1500 | 0.0827 | 0.0400 | 0.0977 | 0.1100 | 0.0752 | 0.1200 | 0.6316 | 0.5600 | 0.0000 | 0.0052 | 0.0103 | 0.0155 | 0.0619 | 0.0825 | 0.0825 | 0.0928 | 0.6495 | 110 | 186 | 267 | 361 | 473 | 591 | 720 | 874 | 1078 | 0.0014 | 42.72 | 7.230 | 0.2482 | 447031.0 | 456000000 | 536000000000 | 698000000000000 | 0.4409 | 0.2151 | 0.0049 | 0.0008 | 0.0213 | 0.0030 | 0.1079 | 0.0134 | 0.1706 | 0.0422 | 0.2262 | 0.1218 | 0.2011 | 0.1874 | 0.1226 | 0.1487 | 0.0823 | 0.1769 | 0.0632 | 0.3059 | 0.0004 | 0.0003 | 0.0013 | 0.0006 | 0.0037 | 0.0034 | 0.0144 | 0.0101 | 0.0397 | 0.0346 | 0.0744 | 0.0570 | 0.0498 | 0.0461 | 0.0699 | 0.0684 | 0.7464 | 0.7795 | 0.0017 | 0.0015 | 0.0017 | 0.0015 | 0.0043 | 0.0070 | 0.0218 | 0.0278 | 0.0519 | 0.0725 | 0.0930 | 0.1147 | 0.0904 | 0.1118 | 0.1106 | 0.1336 | 0.6246 | 0.5296 | 0.0007 | 0.0052 | 0.0059 | 0.0197 | 0.0437 | 0.0749 | 0.0656 | 0.0837 | 0.7007 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 395 | 909 | | 589 | 5786 | 12.0 | 2.37 | 6.24 | 2.23 | 9 | 10 | 11 | 11 | 12 | 12 | 13 | 14 | 15 | 0.0990 | 573 | 0.731 | 73.43 | 17.00 | 0 | 0.3192 | 188 | 0.0185 | 6.32 | 4.289 | 0.3960 | 150.6 | 1953.66 | 26252.6 | 364792 | 0.3695 | 0.2656 | 0.0046 | 0.0000 | 0.0069 | 0.0018 | 0.0324 | 0.0036 | 0.0694 | 0.0164 | 0.1019 | 0.0455 | 0.1343 | 0.0764 | 0.1898 | 0.1218 | 0.1736 | 0.1818 | 0.2870 | 0.5527 | 0.0000 | 0.0000 | 0.0077 | 0.0000 | 0.0174 | 0.0017 | 0.0367 | 0.0156 | 0.0405 | 0.0363 | 0.0656 | 0.0554 | 0.1158 | 0.0606 | 0.1409 | 0.1125 | 0.5753 | 0.7180 | 0.0581 | 0.2857 | 0.0930 | 0.2500 | 0.1860 | 0.1071 | 0.1163 | 0.1786 | 0.1744 | 0.1071 | 0.1163 | 0.0714 | 0.0814 | 0.0000 | 0.1163 | 0.0000 | 0.0581 | 0.0000 | 0.0153 | 0.0337 | 0.0706 | 0.0982 | 0.1135 | 0.1350 | 0.1380 | 0.1503 | 0.2454 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0198 | 11.10 | 4.314 | 0.3248 | 43.9 | 336.777 | 2778.03 | 24382.5 | 0.5530 | 0.1191 | 0.0068 | 0.0000 | 0.0407 | 0.0041 | 0.1143 | 0.0182 | 0.2166 | 0.0597 | 0.2673 | 0.1261 | 0.2088 | 0.2311 | 0.1023 | 0.2725 | 0.0370 | 0.2133 | 0.0062 | 0.0750 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0121 | 0.0032 | 0.0364 | 0.0132 | 0.0907 | 0.0355 | 0.1684 | 0.0778 | 0.2678 | 0.1906 | 0.2778 | 0.3647 | 0.1454 | 0.3144 | 0.1144 | 0.2816 | 0.2397 | 0.3609 | 0.2950 | 0.2346 | 0.1896 | 0.0927 | 0.1073 | 0.0268 | 0.0392 | 0.0034 | 0.0141 | 0.0000 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0090 | 0.0356 | 0.0844 | 0.1569 | 0.2511 | 0.2490 | 0.1644 | 0.0477 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1140 | 800 | | 415 | 10014 | 37.5 | 8.37 | 298.79 | 356.44 | 26 | 30 | 32 | 35 | 37 | 40 | 42 | 45 | 48 | 0.0520 | 521 | 0.700 | 202.20 | 35.61 | 2 | 1.1663 | 484 | 0.0170 | 4.33 | 4.301 | 0.4484 | 1479.7 | 60857.1 | 2600000 | 115000000 | 0.3546 | 0.2708 | 0.0000 | 0.0000 | 0.0083 | 0.0000 | 0.0373 | 0.0025 | 0.1037 | 0.0176 | 0.2241 | 0.0529 | 0.2033 | 0.0856 | 0.1867 | 0.1058 | 0.1743 | 0.1738 | 0.0622 | 0.5617 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0127 | 0.0025 | 0.0538 | 0.0173 | 0.0854 | 0.0519 | 0.0918 | 0.0765 | 0.1076 | 0.0914 | 0.1424 | 0.1136 | 0.5032 | 0.6469 | 0.0533 | 0.2500 | 0.0800 | 0.0000 | 0.0533 | 0.0000 | 0.2000 | 0.3750 | 0.1600 | 0.2500 | 0.1467 | 0.1250 | 0.2133 | 0.0000 | 0.0533 | 0.0000 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0291 | 0.0825 | 0.1311 | 0.1602 | 0.1408 | 0.1748 | 0.2816 | 16 | 19 | 26 | 56 | 134 | 250 | 397 | 574 | 843 | 0.0362 | 50.93 | 5.899 | 0.4283 | 216312.0 | 203000000 | 220000000000 | 261000000000000 | 0.5151 | 0.1616 | 0.0713 | 0.0006 | 0.1940 | 0.0107 | 0.2691 | 0.1146 | 0.2078 | 0.1740 | 0.1352 | 0.1960 | 0.0701 | 0.1829 | 0.0250 | 0.1140 | 0.0163 | 0.1146 | 0.0113 | 0.0926 | 0.0002 | 0.0000 | 0.0002 | 0.0009 | 0.0022 | 0.0018 | 0.0115 | 0.0112 | 0.0583 | 0.0497 | 0.0937 | 0.0790 | 0.0718 | 0.0645 | 0.0976 | 0.0919 | 0.6644 | 0.7012 | 0.0003 | 0.0007 | 0.0018 | 0.0045 | 0.0055 | 0.0111 | 0.0210 | 0.0236 | 0.0735 | 0.0748 | 0.1104 | 0.1219 | 0.0921 | 0.0890 | 0.1052 | 0.1126 | 0.5902 | 0.5618 | 0.0003 | 0.0005 | 0.0027 | 0.0156 | 0.0648 | 0.1058 | 0.0826 | 0.1017 | 0.6260 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 434 | 702 | | 366 | 1008 | 101.8 | 15.33 | 117.32 | 181.93 | 80 | 86 | 92 | 98 | 103 | 108 | 111 | 115 | 124 | 0.2123 | 214 | 1.232 | 111.40 | 47.13 | 1 | 0.7978 | 292 | 0.0164 | 2.19 | 4.307 | 0.5322 | 10587.6 | 1130000 | 122000000 | 13400000000 | 0.3074 | 0.3364 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0000 | 0.0000 | 0.0211 | 0.0055 | 0.0526 | 0.0437 | 0.1719 | 0.1202 | 0.0842 | 0.0328 | 0.0982 | 0.0437 | 0.5684 | 0.7541 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0123 | 0.0055 | 0.0401 | 0.0437 | 0.1204 | 0.1202 | 0.0432 | 0.0328 | 0.0401 | 0.0437 | 0.7438 | 0.7541 | 0.0000 | 0.0000 | 0.0256 | 0.0000 | 0.0256 | 0.0000 | 0.1026 | 0.0000 | 0.1026 | 0.0000 | 0.2051 | 0.0000 | 0.1026 | 0.0000 | 0.2308 | 0.0000 | 0.2051 | 0.0000 | 0.0000 | 0.0000 | 0.0158 | 0.0263 | 0.0526 | 0.1316 | 0.0842 | 0.0947 | 0.5947 | 11 | 13 | 15 | 21 | 33 | 58 | 109 | 190 | 334 | 0.1012 | 55.96 | 4.139 | 0.5623 | 46830.7 | 29000000 | 21700000000 | 18100000000000 | 0.4240 | 0.1879 | 0.1642 | 0.0070 | 0.2537 | 0.0986 | 0.1642 | 0.1690 | 0.1493 | 0.1408 | 0.1194 | 0.1408 | 0.0896 | 0.1620 | 0.0448 | 0.1056 | 0.0149 | 0.0986 | 0.0000 | 0.0775 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0061 | 0.0027 | 0.0457 | 0.0348 | 0.0793 | 0.0668 | 0.1250 | 0.1364 | 0.0854 | 0.0668 | 0.1494 | 0.1337 | 0.5091 | 0.5588 | 0.0000 | 0.0043 | 0.0038 | 0.0086 | 0.0268 | 0.0172 | 0.0345 | 0.0302 | 0.1188 | 0.1207 | 0.1341 | 0.1466 | 0.0996 | 0.1034 | 0.1533 | 0.1767 | 0.4291 | 0.3922 | 0.0000 | 0.0035 | 0.0177 | 0.0389 | 0.0989 | 0.1272 | 0.1095 | 0.1484 | 0.4558 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1201 | 147 | | 25401 | 21792 | 80.3 | 36.47 | 7.79 | 3.16 | 47 | 51 | 55 | 60 | 67 | 79 | 95 | 111 | 130 | 0.0646 | 1407 | 0.643 | 109.48 | 22.02 | 3 | 0.0122 | 311 | 0.0238 | 1.54 | 4.339 | 0.6433 | 7784.7 | 930349 | 141000000 | 27400000000 | 0.3746 | 0.2574 | 0.0183 | 0.0041 | 0.0285 | 0.0101 | 0.0332 | 0.0165 | 0.0445 | 0.0216 | 0.0579 | 0.0307 | 0.0760 | 0.0454 | 0.0991 | 0.0645 | 0.1547 | 0.1011 | 0.4878 | 0.7059 | 0.0063 | 0.0025 | 0.0088 | 0.0051 | 0.0101 | 0.0093 | 0.0128 | 0.0127 | 0.0158 | 0.0171 | 0.0202 | 0.0254 | 0.0263 | 0.0353 | 0.0450 | 0.0545 | 0.8547 | 0.8381 | 0.0029 | 0.0096 | 0.0051 | 0.0076 | 0.0087 | 0.0135 | 0.0154 | 0.0237 | 0.0181 | 0.0317 | 0.0252 | 0.0416 | 0.0356 | 0.0590 | 0.0614 | 0.0833 | 0.8277 | 0.7300 | 0.0039 | 0.0045 | 0.0066 | 0.0106 | 0.0121 | 0.0194 | 0.0250 | 0.0402 | 0.8777 | 4 | 5 | 6 | 7 | 8 | 9 | 9 | 10 | 12 | 0.3288 | 0.54 | 1.489 | 0.7679 | 70.7 | 710.738 | 7758.34 | 90867.1 | 0.5651 | 0.1468 | 0.0276 | 0.0002 | 0.1012 | 0.0027 | 0.1830 | 0.0162 | 0.2395 | 0.0448 | 0.2232 | 0.1065 | 0.1440 | 0.1983 | 0.0622 | 0.2724 | 0.0175 | 0.2494 | 0.0018 | 0.1095 | 0.0011 | 0.0001 | 0.0095 | 0.0007 | 0.0313 | 0.0047 | 0.0743 | 0.0148 | 0.1392 | 0.0405 | 0.2209 | 0.1002 | 0.2544 | 0.1989 | 0.1985 | 0.3291 | 0.0707 | 0.3109 | 0.0837 | 0.3817 | 0.2220 | 0.3524 | 0.2715 | 0.1695 | 0.2102 | 0.0699 | 0.1317 | 0.0232 | 0.0547 | 0.0028 | 0.0218 | 0.0004 | 0.0035 | 0.0000 | 0.0010 | 0.0000 | 0.0061 | 0.0422 | 0.1149 | 0.1974 | 0.2403 | 0.2128 | 0.1308 | 0.0484 | 0.0072 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1046 | 281 | | 697 | 6737 | 49.7 | 11.06 | 107.38 | 98.61 | 35 | 40 | 43 | 46 | 49 | 53 | 56 | 60 | 66 | 0.0687 | 463 | 0.653 | 94.02 | 20.03 | 1 | 0.3989 | 278 | 0.0147 | 2.37 | 4.400 | 0.5020 | 2589.0 | 140960 | 7970000 | 466000000 | 0.3646 | 0.2679 | 0.0024 | 0.0000 | 0.0049 | 0.0000 | 0.0147 | 0.0015 | 0.0293 | 0.0122 | 0.0880 | 0.0518 | 0.1174 | 0.0487 | 0.1418 | 0.0700 | 0.2103 | 0.1035 | 0.3912 | 0.7123 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0179 | 0.0088 | 0.0448 | 0.0423 | 0.0448 | 0.0350 | 0.0538 | 0.0482 | 0.0878 | 0.0496 | 0.7437 | 0.8161 | 0.0000 | 0.0714 | 0.0067 | 0.0714 | 0.0537 | 0.1071 | 0.0604 | 0.2143 | 0.0940 | 0.1429 | 0.0872 | 0.1429 | 0.0940 | 0.2500 | 0.1678 | 0.0000 | 0.4362 | 0.0000 | 0.0000 | 0.0087 | 0.0029 | 0.0320 | 0.0552 | 0.0698 | 0.0756 | 0.1105 | 0.6453 | 16 | 26 | 41 | 57 | 78 | 101 | 132 | 173 | 239 | 0.0142 | 10.47 | 5.299 | 0.4760 | 21253.2 | 5970000 | 2090000000 | 847000000000 | 0.5145 | 0.1485 | 0.0252 | 0.0015 | 0.0572 | 0.0053 | 0.1725 | 0.0393 | 0.1812 | 0.0766 | 0.1764 | 0.1392 | 0.1764 | 0.1702 | 0.1066 | 0.1387 | 0.0640 | 0.1528 | 0.0407 | 0.2764 | 0.0006 | 0.0003 | 0.0013 | 0.0016 | 0.0064 | 0.0045 | 0.0186 | 0.0143 | 0.0578 | 0.0428 | 0.0902 | 0.0659 | 0.0876 | 0.0653 | 0.1139 | 0.0900 | 0.6236 | 0.7153 | 0.0010 | 0.0023 | 0.0048 | 0.0053 | 0.0120 | 0.0164 | 0.0307 | 0.0282 | 0.0801 | 0.0921 | 0.1243 | 0.1268 | 0.0998 | 0.1009 | 0.1166 | 0.1291 | 0.5307 | 0.4988 | 0.0004 | 0.0020 | 0.0086 | 0.0207 | 0.0718 | 0.1128 | 0.0910 | 0.1175 | 0.5752 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 129 | 102 | | 853 | 4631 | 107.8 | 32.30 | 12.53 | 4.15 | 72 | 80 | 87 | 94 | 102 | 110 | 119 | 135 | 159 | 0.1162 | 538 | 1.081 | 46.87 | 17.49 | 1 | 0.1489 | 127 | 0.0142 | 2.79 | 4.517 | 0.4969 | 12655.4 | 1610000 | 221000000 | 32300000000 | 0.4358 | 0.2021 | 0.0024 | 0.0000 | 0.0024 | 0.0028 | 0.0097 | 0.0014 | 0.0607 | 0.0185 | 0.1602 | 0.0541 | 0.1990 | 0.1223 | 0.1553 | 0.0896 | 0.1456 | 0.1181 | 0.2646 | 0.5932 | 0.0017 | 0.0000 | 0.0017 | 0.0012 | 0.0066 | 0.0000 | 0.0249 | 0.0111 | 0.0731 | 0.0382 | 0.0897 | 0.0764 | 0.0797 | 0.0480 | 0.1030 | 0.0640 | 0.6196 | 0.7611 | 0.0000 | 0.0000 | 0.0105 | 0.0000 | 0.0105 | 0.0092 | 0.0316 | 0.0734 | 0.0947 | 0.1376 | 0.1211 | 0.1835 | 0.0789 | 0.1193 | 0.1421 | 0.1835 | 0.5105 | 0.2936 | 0.0055 | 0.0055 | 0.0110 | 0.0440 | 0.0769 | 0.1044 | 0.1181 | 0.1209 | 0.5137 | 7 | 9 | 10 | 11 | 12 | 13 | 14 | 16 | 18 | 0.0078 | 26.38 | 5.307 | 0.2385 | 174.1 | 2649.31 | 43748.6 | 779909 | 0.5184 | 0.1395 | 0.0240 | 0.0003 | 0.0831 | 0.0035 | 0.1717 | 0.0122 | 0.2432 | 0.0319 | 0.2538 | 0.0856 | 0.1461 | 0.1297 | 0.0621 | 0.2158 | 0.0130 | 0.3053 | 0.0030 | 0.2158 | 0.0040 | 0.0000 | 0.0242 | 0.0010 | 0.0646 | 0.0043 | 0.1036 | 0.0183 | 0.1480 | 0.0550 | 0.1705 | 0.0815 | 0.1609 | 0.1399 | 0.1487 | 0.2628 | 0.1755 | 0.4372 | 0.1595 | 0.2552 | 0.1673 | 0.1849 | 0.1399 | 0.1094 | 0.1145 | 0.1484 | 0.1243 | 0.1198 | 0.0920 | 0.0964 | 0.0841 | 0.0495 | 0.0626 | 0.0339 | 0.0558 | 0.0026 | 0.0301 | 0.0872 | 0.1248 | 0.1442 | 0.1442 | 0.1368 | 0.1113 | 0.1076 | 0.1136 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1211 | 385 | | 718 | 1212 | 13.2 | 2.76 | 5.21 | 2.35 | 10 | 11 | 12 | 12 | 13 | 14 | 15 | 16 | 17 | 0.2682 | 325 | 1.148 | 21.38 | 7.81 | 0 | 0.0822 | 59 | 0.0132 | 6.44 | 4.544 | 0.3693 | 180.9 | 2583.19 | 38202.1 | 582955 | 0.4010 | 0.2283 | 0.0000 | 0.0000 | 0.0157 | 0.0000 | 0.0449 | 0.0029 | 0.0966 | 0.0057 | 0.1483 | 0.0474 | 0.2000 | 0.0417 | 0.2337 | 0.0560 | 0.1775 | 0.1365 | 0.0831 | 0.7098 | 0.0000 | 0.0000 | 0.0034 | 0.0000 | 0.0168 | 0.0014 | 0.0387 | 0.0056 | 0.0505 | 0.0435 | 0.0640 | 0.0379 | 0.0993 | 0.0323 | 0.1465 | 0.0660 | 0.5808 | 0.8132 | 0.0604 | 0.3125 | 0.0537 | 0.0625 | 0.1141 | 0.2500 | 0.1342 | 0.3125 | 0.2550 | 0.0625 | 0.2081 | 0.0000 | 0.0738 | 0.0000 | 0.0738 | 0.0000 | 0.0268 | 0.0000 | 0.0097 | 0.0243 | 0.0511 | 0.0560 | 0.0779 | 0.1046 | 0.1192 | 0.2628 | 0.2944 | 2 | 3 | 3 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0284 | 12.09 | 3.933 | 0.3051 | 32.7 | 230.466 | 1783.27 | 14976.5 | 0.4758 | 0.1575 | 0.1219 | 0.0058 | 0.3000 | 0.0437 | 0.3188 | 0.1152 | 0.1688 | 0.2274 | 0.0719 | 0.2332 | 0.0188 | 0.1997 | 0.0000 | 0.1268 | 0.0000 | 0.0423 | 0.0000 | 0.0058 | 0.0000 | 0.0000 | 0.0159 | 0.0000 | 0.0684 | 0.0056 | 0.1233 | 0.0519 | 0.2320 | 0.0935 | 0.2527 | 0.1213 | 0.2002 | 0.2241 | 0.0867 | 0.2676 | 0.0208 | 0.2361 | 0.0281 | 0.0685 | 0.1563 | 0.1980 | 0.2184 | 0.2843 | 0.2926 | 0.2513 | 0.2084 | 0.1396 | 0.0782 | 0.0457 | 0.0160 | 0.0102 | 0.0020 | 0.0025 | 0.0000 | 0.0000 | 0.0000 | 0.0160 | 0.0688 | 0.1290 | 0.2359 | 0.2531 | 0.2015 | 0.0835 | 0.0123 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 902 | 486 | | 1571 | 8752 | 79.8 | 18.38 | 25.85 | 63.61 | 59 | 62 | 66 | 70 | 75 | 84 | 92 | 99 | 106 | 0.0978 | 856 | 0.759 | 104.01 | 24.21 | 3 | 0.1827 | 287 | 0.0137 | 2.82 | 4.627 | 0.5218 | 6709.4 | 592170 | 54600000 | 5230000000 | 0.4037 | 0.2309 | 0.0050 | 0.0000 | 0.0099 | 0.0000 | 0.0236 | 0.0000 | 0.0459 | 0.0067 | 0.0980 | 0.0299 | 0.1613 | 0.0552 | 0.1365 | 0.0579 | 0.1675 | 0.0685 | 0.3524 | 0.7818 | 0.0033 | 0.0000 | 0.0033 | 0.0000 | 0.0117 | 0.0000 | 0.0208 | 0.0045 | 0.0400 | 0.0248 | 0.0650 | 0.0446 | 0.0550 | 0.0299 | 0.0708 | 0.0350 | 0.7300 | 0.8611 | 0.0000 | 0.0299 | 0.0000 | 0.0746 | 0.0203 | 0.0597 | 0.0330 | 0.1642 | 0.0787 | 0.1045 | 0.1320 | 0.1493 | 0.1142 | 0.0746 | 0.1345 | 0.1194 | 0.4873 | 0.2239 | 0.0000 | 0.0057 | 0.0057 | 0.0213 | 0.0355 | 0.0682 | 0.0540 | 0.0753 | 0.7344 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 12 | 53 | 0.2949 | 7.14 | 2.200 | 0.6924 | 4714.0 | 1480000 | 590000000 | 281000000000 | 0.4076 | 0.1755 | 0.0603 | 0.0111 | 0.2915 | 0.0379 | 0.4824 | 0.1737 | 0.1407 | 0.2517 | 0.0101 | 0.2539 | 0.0101 | 0.1403 | 0.0050 | 0.0802 | 0.0000 | 0.0379 | 0.0000 | 0.0134 | 0.0008 | 0.0035 | 0.0041 | 0.0077 | 0.0154 | 0.0153 | 0.0170 | 0.0251 | 0.0519 | 0.0537 | 0.0787 | 0.0760 | 0.0463 | 0.0530 | 0.0779 | 0.0746 | 0.7078 | 0.6911 | 0.0019 | 0.0030 | 0.0039 | 0.0020 | 0.0048 | 0.0030 | 0.0087 | 0.0071 | 0.0571 | 0.0569 | 0.0871 | 0.0944 | 0.0600 | 0.0650 | 0.0794 | 0.0792 | 0.6970 | 0.6893 | 0.0018 | 0.0090 | 0.0045 | 0.0170 | 0.0502 | 0.0806 | 0.0556 | 0.0762 | 0.7052 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1251 | 214 | | 356 | 5823 | 35.2 | 7.41 | 113.18 | 175.08 | 27 | 29 | 30 | 32 | 34 | 37 | 39 | 42 | 46 | 0.0792 | 461 | 0.420 | 101.19 | 15.26 | 1 | 0.8736 | 311 | 0.0113 | 6.98 | 4.700 | 0.3318 | 1292.1 | 49511.8 | 1970000 | 81800000 | 0.4112 | 0.2070 | 0.0000 | 0.0000 | 0.0044 | 0.0000 | 0.0439 | 0.0000 | 0.0877 | 0.0118 | 0.1711 | 0.0708 | 0.1798 | 0.0678 | 0.2719 | 0.1121 | 0.1491 | 0.1563 | 0.0921 | 0.5811 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0000 | 0.0261 | 0.0113 | 0.0554 | 0.0592 | 0.0782 | 0.0563 | 0.1401 | 0.0676 | 0.1759 | 0.0901 | 0.5049 | 0.7155 | 0.0127 | 0.0625 | 0.0000 | 0.1250 | 0.0759 | 0.0625 | 0.2532 | 0.2500 | 0.1646 | 0.1250 | 0.1772 | 0.1875 | 0.1139 | 0.1250 | 0.1013 | 0.0625 | 0.1013 | 0.0000 | 0.0000 | 0.0242 | 0.0424 | 0.0667 | 0.1030 | 0.1576 | 0.1455 | 0.1636 | 0.2970 | 16 | 20 | 25 | 33 | 45 | 68 | 103 | 161 | 264 | 0.0724 | 6.00 | 4.044 | 0.6522 | 43457.4 | 30200000 | 26300000000 | 25200000000000 | 0.6089 | 0.0954 | 0.0138 | 0.0044 | 0.0881 | 0.0044 | 0.1796 | 0.0413 | 0.1503 | 0.0739 | 0.1658 | 0.1706 | 0.1330 | 0.1715 | 0.1278 | 0.1407 | 0.0950 | 0.1416 | 0.0466 | 0.2515 | 0.0000 | 0.0009 | 0.0015 | 0.0004 | 0.0041 | 0.0017 | 0.0164 | 0.0133 | 0.0590 | 0.0506 | 0.0878 | 0.0665 | 0.0678 | 0.0545 | 0.0965 | 0.0982 | 0.6668 | 0.7139 | 0.0015 | 0.0000 | 0.0015 | 0.0017 | 0.0037 | 0.0050 | 0.0161 | 0.0209 | 0.0701 | 0.0771 | 0.1103 | 0.1131 | 0.0621 | 0.0737 | 0.1169 | 0.1307 | 0.6180 | 0.5779 | 0.0006 | 0.0031 | 0.0043 | 0.0210 | 0.0611 | 0.0945 | 0.0667 | 0.1050 | 0.6436 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 992 | 554 | | 458 | 453 | 58.6 | 18.24 | 15.98 | 3.18 | 38 | 42 | 46 | 52 | 56 | 61 | 66 | 72 | 84 | 0.4040 | 183 | 0.735 | 110.07 | 27.07 | 1 | 0.6135 | 281 | 0.0119 | 5.25 | 4.713 | 0.4351 | 3769.0 | 265175 | 20300000 | 1680000000 | 0.3546 | 0.2594 | 0.0000 | 0.0000 | 0.0199 | 0.0000 | 0.0448 | 0.0000 | 0.0597 | 0.0052 | 0.1294 | 0.0735 | 0.2139 | 0.1417 | 0.1791 | 0.0761 | 0.1343 | 0.1155 | 0.2189 | 0.5879 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0164 | 0.0046 | 0.0656 | 0.0371 | 0.1049 | 0.0928 | 0.0721 | 0.0278 | 0.0951 | 0.0603 | 0.6459 | 0.7773 | 0.0096 | 0.0000 | 0.0000 | 0.0000 | 0.0096 | 0.0600 | 0.0673 | 0.1800 | 0.2019 | 0.1000 | 0.1731 | 0.2800 | 0.0865 | 0.1400 | 0.1635 | 0.0600 | 0.2885 | 0.1800 | 0.0000 | 0.0000 | 0.0048 | 0.0335 | 0.1435 | 0.1483 | 0.1100 | 0.1627 | 0.3971 | 12 | 13 | 14 | 15 | 16 | 17 | 17 | 18 | 20 | 0.8738 | 0.06 | 0.306 | 0.9702 | 265.5 | 4574.87 | 81636.7 | 1510000 | 0.5349 | 0.1049 | 0.0031 | 0.0000 | 0.0217 | 0.0000 | 0.0683 | 0.0046 | 0.1211 | 0.0207 | 0.2050 | 0.1359 | 0.1739 | 0.1544 | 0.1739 | 0.1613 | 0.1801 | 0.1521 | 0.0528 | 0.3710 | 0.0026 | 0.0000 | 0.0078 | 0.0000 | 0.0284 | 0.0045 | 0.0413 | 0.0089 | 0.1835 | 0.1250 | 0.1550 | 0.1473 | 0.1576 | 0.1518 | 0.1938 | 0.1384 | 0.2300 | 0.4241 | 0.2923 | 0.5000 | 0.1846 | 0.2143 | 0.1385 | 0.2143 | 0.1846 | 0.0714 | 0.1077 | 0.0000 | 0.0615 | 0.0000 | 0.0308 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0586 | 0.1328 | 0.1445 | 0.1758 | 0.1680 | 0.1367 | 0.1055 | 0.0586 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 146 | 51 | | 354 | 2232 | 83.5 | 10.81 | 232.77 | 142.92 | 70 | 73 | 77 | 80 | 83 | 86 | 89 | 94 | 99 | 0.1223 | 273 | 1.033 | 88.84 | 22.85 | 0 | 0.5791 | 205 | 0.0101 | 9.66 | 4.753 | 0.3349 | 7088.7 | 611712 | 53600000 | 4780000000 | 0.4194 | 0.1966 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0130 | 0.0028 | 0.0357 | 0.0085 | 0.0779 | 0.0397 | 0.1331 | 0.1473 | 0.1331 | 0.0368 | 0.2110 | 0.0822 | 0.3929 | 0.6827 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0030 | 0.0028 | 0.0178 | 0.0056 | 0.0562 | 0.0424 | 0.1124 | 0.1441 | 0.0621 | 0.0339 | 0.1213 | 0.0763 | 0.6243 | 0.6949 | 0.0000 | 1.0000 | 0.1000 | 0.0000 | 0.3667 | 0.0000 | 0.1000 | 0.0000 | 0.1667 | 0.0000 | 0.1333 | 0.0000 | 0.0667 | 0.0000 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0430 | 0.0699 | 0.1505 | 0.1720 | 0.1290 | 0.1559 | 0.2688 | 68 | 106 | 142 | 176 | 210 | 248 | 292 | 342 | 423 | 0.0013 | 85.74 | 6.901 | 0.1836 | 74597.8 | 29500000 | 13700000000 | 7190000000000 | 0.4379 | 0.1909 | 0.0169 | 0.0028 | 0.0639 | 0.0075 | 0.1899 | 0.0197 | 0.2199 | 0.0563 | 0.1748 | 0.1315 | 0.1485 | 0.1840 | 0.0846 | 0.1897 | 0.0639 | 0.1615 | 0.0376 | 0.2469 | 0.0008 | 0.0013 | 0.0016 | 0.0019 | 0.0055 | 0.0044 | 0.0181 | 0.0120 | 0.0604 | 0.0405 | 0.1319 | 0.0790 | 0.0981 | 0.0765 | 0.1389 | 0.0967 | 0.5447 | 0.6877 | 0.0013 | 0.0039 | 0.0054 | 0.0135 | 0.0148 | 0.0271 | 0.0620 | 0.0832 | 0.1334 | 0.1605 | 0.1536 | 0.1741 | 0.1361 | 0.1586 | 0.1860 | 0.1470 | 0.3073 | 0.2321 | 0.0000 | 0.0020 | 0.0121 | 0.0302 | 0.1099 | 0.1532 | 0.1149 | 0.1734 | 0.4042 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 703 | 330 | | 1517 | 7267 | 260.9 | 69.91 | 59.78 | 117.99 | 178 | 191 | 206 | 227 | 248 | 274 | 304 | 331 | 369 | 0.0860 | 625 | 1.115 | 107.79 | 38.05 | 1 | 0.1793 | 272 | 0.0105 | 1.72 | 4.763 | 0.5649 | 72953.0 | 21700000 | 6830000000 | 2240000000000 | 0.3508 | 0.2996 | 0.0016 | 0.0000 | 0.0031 | 0.0000 | 0.0062 | 0.0015 | 0.0171 | 0.0067 | 0.0715 | 0.0340 | 0.0964 | 0.0503 | 0.1026 | 0.0392 | 0.1291 | 0.0673 | 0.5723 | 0.8010 | 0.0010 | 0.0000 | 0.0019 | 0.0000 | 0.0019 | 0.0000 | 0.0057 | 0.0040 | 0.0306 | 0.0224 | 0.0373 | 0.0369 | 0.0335 | 0.0257 | 0.0450 | 0.0383 | 0.8431 | 0.8727 | 0.0025 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0061 | 0.0124 | 0.0549 | 0.0423 | 0.0610 | 0.0547 | 0.0549 | 0.0448 | 0.1220 | 0.0821 | 0.0854 | 0.7512 | 0.6159 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0337 | 0.0527 | 0.0366 | 0.0439 | 0.8228 | 7 | 8 | 9 | 10 | 11 | 15 | 28 | 57 | 188 | 0.1752 | 2.71 | 2.781 | 0.6871 | 17493.2 | 7830000 | 4090000000 | 2340000000000 | 0.4255 | 0.2007 | 0.0273 | 0.0043 | 0.0648 | 0.0086 | 0.1297 | 0.0114 | 0.2150 | 0.0643 | 0.2116 | 0.1186 | 0.1502 | 0.1686 | 0.1229 | 0.1429 | 0.0614 | 0.1629 | 0.0171 | 0.3186 | 0.0031 | 0.0010 | 0.0037 | 0.0021 | 0.0074 | 0.0026 | 0.0155 | 0.0129 | 0.0372 | 0.0290 | 0.0440 | 0.0403 | 0.0415 | 0.0445 | 0.0551 | 0.0672 | 0.7926 | 0.8004 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0023 | 0.0024 | 0.0053 | 0.0097 | 0.0371 | 0.0308 | 0.0393 | 0.0559 | 0.0446 | 0.0454 | 0.0598 | 0.0608 | 0.8086 | 0.7950 | 0.0000 | 0.0021 | 0.0049 | 0.0119 | 0.0295 | 0.0372 | 0.0400 | 0.0534 | 0.8209 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 644 | 300 | | 381 | 806 | 12.1 | 3.51 | 5.40 | 1.98 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 17 | 0.3623 | 292 | 0.804 | 32.02 | 8.25 | 0 | 0.2283 | 87 | 0.0100 | 11.54 | 4.797 | 0.2819 | 158.7 | 2234.75 | 33514.1 | 530731 | 0.4187 | 0.2080 | 0.0000 | 0.0000 | 0.0459 | 0.0000 | 0.1429 | 0.0033 | 0.1837 | 0.0262 | 0.2143 | 0.1082 | 0.2245 | 0.1934 | 0.1071 | 0.1836 | 0.0663 | 0.2787 | 0.0153 | 0.2066 | 0.0000 | 0.0000 | 0.0179 | 0.0000 | 0.0286 | 0.0000 | 0.0536 | 0.0143 | 0.0929 | 0.0602 | 0.1071 | 0.0659 | 0.1464 | 0.1347 | 0.1929 | 0.2063 | 0.3607 | 0.5186 | 0.0238 | 0.0682 | 0.1310 | 0.2045 | 0.1310 | 0.1136 | 0.2262 | 0.1591 | 0.1667 | 0.1364 | 0.1548 | 0.2273 | 0.0595 | 0.0455 | 0.0833 | 0.0455 | 0.0238 | 0.0000 | 0.0094 | 0.0330 | 0.0377 | 0.0566 | 0.1226 | 0.1509 | 0.1462 | 0.2217 | 0.2217 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0262 | 8.53 | 4.026 | 0.3635 | 33.1 | 222.937 | 1630.58 | 12844 | 0.5218 | 0.1301 | 0.0340 | 0.0037 | 0.1671 | 0.0201 | 0.2125 | 0.0713 | 0.2351 | 0.1755 | 0.2153 | 0.2194 | 0.0963 | 0.2102 | 0.0397 | 0.1481 | 0.0000 | 0.1097 | 0.0000 | 0.0420 | 0.0014 | 0.0013 | 0.0029 | 0.0000 | 0.0203 | 0.0053 | 0.0695 | 0.0420 | 0.1462 | 0.1183 | 0.1650 | 0.1367 | 0.1838 | 0.1380 | 0.2489 | 0.2076 | 0.1621 | 0.3509 | 0.0355 | 0.1308 | 0.1450 | 0.2664 | 0.2367 | 0.2617 | 0.2426 | 0.1215 | 0.1538 | 0.1308 | 0.0947 | 0.0607 | 0.0562 | 0.0187 | 0.0266 | 0.0000 | 0.0089 | 0.0093 | 0.0018 | 0.0235 | 0.0868 | 0.1374 | 0.1953 | 0.2441 | 0.2080 | 0.0759 | 0.0271 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 193 | 840 | | 364 | 9991 | 79.4 | 12.33 | 120.69 | 125.11 | 64 | 69 | 71 | 74 | 78 | 82 | 86 | 91 | 97 | 0.0656 | 655 | 0.892 | 100.23 | 30.02 | 0 | 0.7033 | 256 | 0.0097 | 8.20 | 4.818 | 0.3329 | 6458.0 | 537560 | 45800000 | 3980000000 | 0.4026 | 0.2222 | 0.0000 | 0.0000 | 0.0248 | 0.0028 | 0.0106 | 0.0055 | 0.0496 | 0.0138 | 0.1028 | 0.0608 | 0.1950 | 0.1326 | 0.1915 | 0.0856 | 0.2340 | 0.1105 | 0.1915 | 0.5884 | 0.0000 | 0.0000 | 0.0210 | 0.0027 | 0.0060 | 0.0055 | 0.0330 | 0.0137 | 0.0571 | 0.0604 | 0.1171 | 0.1319 | 0.0781 | 0.0742 | 0.1171 | 0.0934 | 0.5706 | 0.6181 | 0.0196 | 0.0000 | 0.0980 | 1.0000 | 0.0392 | 0.0000 | 0.2549 | 0.0000 | 0.1765 | 0.0000 | 0.2157 | 0.0000 | 0.0980 | 0.0000 | 0.0980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0229 | 0.0571 | 0.0400 | 0.0971 | 0.1371 | 0.1371 | 0.1771 | 0.3314 | 24 | 37 | 47 | 57 | 70 | 90 | 126 | 190 | 293 | 0.0082 | 25.67 | 5.863 | 0.4219 | 30214.6 | 11500000 | 5470000000 | 2990000000000 | 0.6670 | 0.0790 | 0.0168 | 0.0063 | 0.0841 | 0.0145 | 0.1639 | 0.0396 | 0.1869 | 0.0903 | 0.1913 | 0.1538 | 0.1665 | 0.1778 | 0.0939 | 0.1436 | 0.0709 | 0.1429 | 0.0257 | 0.2312 | 0.0013 | 0.0029 | 0.0042 | 0.0050 | 0.0088 | 0.0091 | 0.0255 | 0.0213 | 0.0682 | 0.0615 | 0.1043 | 0.0886 | 0.0823 | 0.0797 | 0.1139 | 0.1042 | 0.5915 | 0.6276 | 0.0008 | 0.0009 | 0.0049 | 0.0070 | 0.0167 | 0.0127 | 0.0318 | 0.0417 | 0.0864 | 0.0961 | 0.1262 | 0.1298 | 0.0936 | 0.1039 | 0.1259 | 0.1373 | 0.5136 | 0.4706 | 0.0016 | 0.0055 | 0.0109 | 0.0257 | 0.0792 | 0.1136 | 0.0911 | 0.1171 | 0.5553 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 56 | 911 | | 384 | 7332 | 60.6 | 12.76 | 165.06 | 118.18 | 45 | 50 | 53 | 57 | 60 | 63 | 67 | 71 | 76 | 0.0614 | 450 | 0.519 | 130.54 | 26.91 | 0 | 1.0260 | 394 | 0.0099 | 9.19 | 4.826 | 0.3167 | 3828.9 | 252540 | 17400000 | 1250000000 | 0.4554 | 0.1729 | 0.0036 | 0.0000 | 0.0109 | 0.0028 | 0.0182 | 0.0055 | 0.0691 | 0.0194 | 0.1309 | 0.0720 | 0.1709 | 0.1219 | 0.1782 | 0.0914 | 0.2000 | 0.1607 | 0.2182 | 0.5263 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0093 | 0.0027 | 0.0247 | 0.0107 | 0.0957 | 0.0587 | 0.1235 | 0.1147 | 0.1173 | 0.0667 | 0.1420 | 0.1333 | 0.4877 | 0.6107 | 0.1020 | 0.0000 | 0.0612 | 0.1429 | 0.1224 | 0.0714 | 0.1020 | 0.3571 | 0.1633 | 0.2857 | 0.1837 | 0.0714 | 0.1633 | 0.0714 | 0.0612 | 0.0000 | 0.0408 | 0.0000 | 0.0053 | 0.0000 | 0.0106 | 0.0638 | 0.1596 | 0.1702 | 0.1596 | 0.1915 | 0.2394 | 18 | 37 | 71 | 117 | 158 | 195 | 232 | 274 | 329 | 0.0075 | 22.50 | 6.081 | 0.3343 | 41207.1 | 12200000 | 3970000000 | 1400000000000 | 0.4642 | 0.1955 | 0.0148 | 0.0016 | 0.1134 | 0.0089 | 0.1997 | 0.0335 | 0.1935 | 0.0895 | 0.1671 | 0.1734 | 0.1507 | 0.1952 | 0.0870 | 0.1593 | 0.0583 | 0.1613 | 0.0155 | 0.1774 | 0.0000 | 0.0000 | 0.0005 | 0.0013 | 0.0024 | 0.0011 | 0.0128 | 0.0077 | 0.0443 | 0.0302 | 0.0775 | 0.0562 | 0.0828 | 0.0523 | 0.1239 | 0.0826 | 0.6558 | 0.7687 | 0.0003 | 0.0023 | 0.0052 | 0.0099 | 0.0108 | 0.0185 | 0.0241 | 0.0468 | 0.0927 | 0.1342 | 0.1524 | 0.1640 | 0.1405 | 0.1486 | 0.1552 | 0.1721 | 0.4188 | 0.3036 | 0.0011 | 0.0025 | 0.0040 | 0.0178 | 0.0627 | 0.1136 | 0.1110 | 0.1627 | 0.5246 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1074 | 469 | | 856 | 4211 | 285.4 | 67.25 | 6.42 | 2.65 | 204 | 219 | 238 | 258 | 279 | 298 | 314 | 342 | 392 | 0.0912 | 384 | 0.307 | 78.41 | 12.65 | 1 | 0.3540 | 303 | 0.0100 | 2.29 | 4.835 | 0.5114 | 85984.1 | 27300000 | 9080000000 | 3150000000000 | 0.3537 | 0.2878 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0190 | 0.0026 | 0.0634 | 0.0408 | 0.1142 | 0.0829 | 0.0846 | 0.0421 | 0.1078 | 0.0523 | 0.6110 | 0.7793 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0078 | 0.0012 | 0.0310 | 0.0315 | 0.0620 | 0.0619 | 0.0326 | 0.0245 | 0.0419 | 0.0304 | 0.8248 | 0.8505 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0139 | 0.0407 | 0.0139 | 0.0407 | 0.1389 | 0.0872 | 0.1389 | 0.0814 | 0.0694 | 0.0930 | 0.1250 | 0.6453 | 0.5000 | 0.0000 | 0.0000 | 0.0025 | 0.0100 | 0.0549 | 0.0549 | 0.0499 | 0.0998 | 0.7282 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 10 | 0.0710 | 0.33 | 0.864 | 0.2971 | 48.3 | 412.798 | 3958 | 42046.3 | 0.4542 | 0.1770 | 0.0146 | 0.0016 | 0.0652 | 0.0082 | 0.1429 | 0.0216 | 0.2233 | 0.0554 | 0.2280 | 0.0976 | 0.2045 | 0.1628 | 0.0871 | 0.2473 | 0.0323 | 0.2561 | 0.0021 | 0.1494 | 0.0003 | 0.0000 | 0.0085 | 0.0008 | 0.0241 | 0.0043 | 0.0564 | 0.0112 | 0.1146 | 0.0394 | 0.1580 | 0.0765 | 0.1970 | 0.1501 | 0.1932 | 0.2793 | 0.2479 | 0.4384 | 0.0927 | 0.1488 | 0.1418 | 0.1187 | 0.1354 | 0.1116 | 0.1297 | 0.1259 | 0.1088 | 0.1731 | 0.1128 | 0.1173 | 0.1225 | 0.0959 | 0.0798 | 0.0658 | 0.0766 | 0.0429 | 0.0125 | 0.0467 | 0.0780 | 0.1010 | 0.1263 | 0.1364 | 0.1335 | 0.1557 | 0.2100 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 576 | 951 | | 438 | 2028 | 54.0 | 7.53 | 156.62 | 225.49 | 45 | 48 | 49 | 51 | 54 | 55 | 57 | 60 | 63 | 0.1686 | 342 | 0.895 | 78.01 | 22.20 | 1 | 0.4566 | 200 | 0.0096 | 10.55 | 4.855 | 0.3142 | 2971.3 | 166797 | 9560000 | 559000000 | 0.3875 | 0.2379 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0023 | 0.0262 | 0.0092 | 0.0945 | 0.0624 | 0.1260 | 0.0901 | 0.1811 | 0.0693 | 0.2520 | 0.1085 | 0.3123 | 0.6582 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0023 | 0.0193 | 0.0091 | 0.0578 | 0.0594 | 0.0988 | 0.0868 | 0.1012 | 0.0548 | 0.1518 | 0.0868 | 0.5639 | 0.7009 | 0.1765 | 0.0000 | 0.1765 | 0.2000 | 0.0588 | 0.2000 | 0.1765 | 0.6000 | 0.1176 | 0.0000 | 0.0294 | 0.0000 | 0.1765 | 0.0000 | 0.0882 | 0.0000 | 0.0000 | 0.0000 | 0.0136 | 0.0318 | 0.0227 | 0.0773 | 0.1364 | 0.1364 | 0.1500 | 0.2091 | 0.2227 | 17 | 21 | 28 | 41 | 64 | 99 | 142 | 241 | 425 | 0.0260 | 58.20 | 5.100 | 0.4350 | 75349.7 | 58100000 | 55000000000 | 57800000000000 | 0.4831 | 0.1439 | 0.1056 | 0.0000 | 0.2609 | 0.0221 | 0.2050 | 0.1838 | 0.0870 | 0.1569 | 0.1242 | 0.1936 | 0.0870 | 0.1201 | 0.0683 | 0.0760 | 0.0435 | 0.1176 | 0.0186 | 0.1299 | 0.0030 | 0.0000 | 0.0030 | 0.0036 | 0.0151 | 0.0059 | 0.0256 | 0.0119 | 0.0935 | 0.0973 | 0.1704 | 0.1269 | 0.0905 | 0.0973 | 0.1297 | 0.1329 | 0.4691 | 0.5243 | 0.0020 | 0.0000 | 0.0060 | 0.0069 | 0.0159 | 0.0207 | 0.0239 | 0.0345 | 0.1076 | 0.1310 | 0.1853 | 0.1816 | 0.1036 | 0.0989 | 0.1474 | 0.1402 | 0.4084 | 0.3862 | 0.0000 | 0.0035 | 0.0159 | 0.0265 | 0.1044 | 0.1805 | 0.0973 | 0.1274 | 0.4442 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1156 | 346 | | 318 | 920 | 14.3 | 4.68 | 5.30 | 2.36 | 9 | 10 | 12 | 13 | 14 | 14 | 16 | 17 | 21 | 0.2957 | 272 | 1.375 | 23.54 | 9.49 | 0 | 0.1855 | 59 | 0.0096 | 15.54 | 4.861 | 0.2753 | 224.9 | 3921.78 | 75133.4 | 1570000 | 0.3709 | 0.2571 | 0.0068 | 0.0000 | 0.0608 | 0.0000 | 0.0541 | 0.0000 | 0.1689 | 0.0498 | 0.2365 | 0.0805 | 0.1419 | 0.0958 | 0.1824 | 0.1149 | 0.1149 | 0.2835 | 0.0338 | 0.3755 | 0.0000 | 0.0000 | 0.0177 | 0.0000 | 0.0044 | 0.0000 | 0.0354 | 0.0301 | 0.1150 | 0.0569 | 0.0885 | 0.0535 | 0.1726 | 0.0635 | 0.1770 | 0.1639 | 0.3894 | 0.6321 | 0.0128 | 0.0789 | 0.0513 | 0.0526 | 0.0641 | 0.0263 | 0.0641 | 0.0526 | 0.1154 | 0.1842 | 0.1667 | 0.0789 | 0.1667 | 0.1579 | 0.1795 | 0.1842 | 0.1795 | 0.1842 | 0.0000 | 0.0248 | 0.0745 | 0.1056 | 0.1242 | 0.1242 | 0.1553 | 0.1553 | 0.2360 | 3 | 3 | 5 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0283 | 11.90 | 3.904 | 0.3091 | 33.7 | 240.012 | 1881.41 | 15989.2 | 0.5312 | 0.1181 | 0.1609 | 0.0033 | 0.2913 | 0.0384 | 0.3000 | 0.0801 | 0.1913 | 0.1436 | 0.0522 | 0.2053 | 0.0043 | 0.2354 | 0.0000 | 0.1803 | 0.0000 | 0.0835 | 0.0000 | 0.0301 | 0.0000 | 0.0000 | 0.0124 | 0.0000 | 0.0495 | 0.0132 | 0.1533 | 0.0444 | 0.2059 | 0.1187 | 0.2384 | 0.1007 | 0.2043 | 0.1775 | 0.1130 | 0.2818 | 0.0232 | 0.2638 | 0.0240 | 0.1277 | 0.0962 | 0.2681 | 0.2308 | 0.2766 | 0.2837 | 0.2383 | 0.2139 | 0.0766 | 0.1106 | 0.0128 | 0.0313 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0124 | 0.0496 | 0.1597 | 0.2031 | 0.2357 | 0.2031 | 0.1132 | 0.0233 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1205 | 176 | | 372 | 2800 | 40.2 | 10.05 | 84.88 | 173.91 | 28 | 30 | 34 | 37 | 39 | 41 | 45 | 49 | 53 | 0.1139 | 319 | 0.581 | 191.64 | 52.00 | 2 | 1.5618 | 581 | 0.0086 | 8.20 | 4.933 | 0.3440 | 1713.9 | 77670.5 | 3730000 | 189000000 | 0.3953 | 0.2248 | 0.0051 | 0.0000 | 0.0154 | 0.0000 | 0.0359 | 0.0000 | 0.1333 | 0.0088 | 0.1744 | 0.0821 | 0.1897 | 0.0645 | 0.2154 | 0.1026 | 0.1333 | 0.1378 | 0.0974 | 0.6041 | 0.0036 | 0.0000 | 0.0108 | 0.0000 | 0.0108 | 0.0000 | 0.0502 | 0.0054 | 0.0681 | 0.0622 | 0.0681 | 0.0514 | 0.0968 | 0.0514 | 0.1147 | 0.0784 | 0.5771 | 0.7514 | 0.0000 | 0.0000 | 0.0357 | 0.0345 | 0.1190 | 0.0690 | 0.0238 | 0.2069 | 0.1786 | 0.1379 | 0.1667 | 0.0345 | 0.0952 | 0.2069 | 0.1548 | 0.1379 | 0.2262 | 0.1724 | 0.0056 | 0.0056 | 0.0222 | 0.0444 | 0.0778 | 0.0944 | 0.0889 | 0.1778 | 0.4833 | 15 | 17 | 19 | 21 | 23 | 27 | 32 | 79 | 241 | 0.2089 | 3.35 | 2.782 | 0.7521 | 37440.5 | 29600000 | 28700000000 | 30700000000000 | 0.7152 | 0.0493 | 0.0130 | 0.0061 | 0.1299 | 0.0242 | 0.2987 | 0.0242 | 0.1948 | 0.0848 | 0.1429 | 0.2061 | 0.0779 | 0.2485 | 0.0649 | 0.1333 | 0.0260 | 0.1455 | 0.0519 | 0.1273 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0047 | 0.0120 | 0.0126 | 0.0342 | 0.0346 | 0.0496 | 0.0362 | 0.0479 | 0.0472 | 0.0803 | 0.0849 | 0.7761 | 0.7799 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0021 | 0.0138 | 0.0085 | 0.0472 | 0.0446 | 0.0591 | 0.0807 | 0.0571 | 0.0573 | 0.1004 | 0.1083 | 0.7185 | 0.6985 | 0.0000 | 0.0000 | 0.0018 | 0.0091 | 0.0453 | 0.0507 | 0.0562 | 0.0888 | 0.7482 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1179 | 272 | | 484 | 417 | 15.1 | 6.24 | 5.44 | 2.42 | 10 | 11 | 12 | 12 | 13 | 15 | 16 | 18 | 23 | 0.4964 | 207 | 0.834 | 37.74 | 12.04 | 0 | 0.2397 | 116 | 0.0096 | 14.01 | 4.972 | 0.3037 | 265.5 | 5621.95 | 142364 | 4170000 | 0.3690 | 0.2458 | 0.0041 | 0.0000 | 0.0207 | 0.0000 | 0.0664 | 0.0000 | 0.1660 | 0.0426 | 0.1618 | 0.0727 | 0.1826 | 0.1053 | 0.1826 | 0.1328 | 0.1369 | 0.1529 | 0.0788 | 0.4937 | 0.0000 | 0.0000 | 0.0146 | 0.0000 | 0.0292 | 0.0000 | 0.0437 | 0.0325 | 0.0787 | 0.0433 | 0.1108 | 0.0584 | 0.1224 | 0.0714 | 0.1866 | 0.0952 | 0.4140 | 0.6991 | 0.0392 | 0.0000 | 0.0392 | 0.0476 | 0.0686 | 0.0635 | 0.0490 | 0.0794 | 0.0784 | 0.1429 | 0.1961 | 0.1111 | 0.0980 | 0.1111 | 0.1275 | 0.1111 | 0.3039 | 0.3333 | 0.0051 | 0.0256 | 0.0718 | 0.0821 | 0.1026 | 0.1333 | 0.1385 | 0.1179 | 0.3231 | 3 | 3 | 4 | 5 | 5 | 7 | 7 | 7 | 9 | 0.0300 | 14.00 | 3.917 | 0.2952 | 35.4 | 257.772 | 2032.6 | 17052.4 | 0.3900 | 0.1941 | 0.1136 | 0.0290 | 0.2652 | 0.0773 | 0.2803 | 0.2174 | 0.1667 | 0.2560 | 0.0909 | 0.2029 | 0.0530 | 0.1353 | 0.0303 | 0.0628 | 0.0000 | 0.0145 | 0.0000 | 0.0048 | 0.0032 | 0.0000 | 0.0194 | 0.0079 | 0.0809 | 0.0159 | 0.1748 | 0.0714 | 0.2201 | 0.1720 | 0.2071 | 0.1746 | 0.1909 | 0.2302 | 0.0906 | 0.2169 | 0.0129 | 0.1111 | 0.0734 | 0.0760 | 0.1751 | 0.2047 | 0.3277 | 0.3392 | 0.2260 | 0.2222 | 0.1186 | 0.0877 | 0.0395 | 0.0292 | 0.0395 | 0.0409 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0433 | 0.1300 | 0.2202 | 0.2238 | 0.1805 | 0.1336 | 0.0542 | 0.0072 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 176 | 439 | | 2149 | 10252 | 192.6 | 59.91 | 8.87 | 3.44 | 120 | 133 | 148 | 165 | 184 | 205 | 228 | 254 | 283 | 0.0694 | 712 | 0.822 | 57.98 | 20.03 | 1 | 0.0814 | 175 | 0.0084 | 2.12 | 4.986 | 0.5414 | 40700.9 | 9310000 | 2270000000 | 578000000000 | 0.3740 | 0.2645 | 0.0013 | 0.0012 | 0.0076 | 0.0030 | 0.0076 | 0.0041 | 0.0278 | 0.0100 | 0.0682 | 0.0349 | 0.1174 | 0.0573 | 0.1023 | 0.0473 | 0.1452 | 0.0810 | 0.5227 | 0.7612 | 0.0000 | 0.0010 | 0.0043 | 0.0020 | 0.0021 | 0.0030 | 0.0100 | 0.0070 | 0.0242 | 0.0214 | 0.0356 | 0.0349 | 0.0342 | 0.0244 | 0.0456 | 0.0449 | 0.8439 | 0.8614 | 0.0000 | 0.0064 | 0.0000 | 0.0032 | 0.0065 | 0.0127 | 0.0196 | 0.0255 | 0.0344 | 0.0541 | 0.0687 | 0.0637 | 0.0507 | 0.0732 | 0.0589 | 0.0669 | 0.7610 | 0.6943 | 0.0000 | 0.0000 | 0.0072 | 0.0196 | 0.0319 | 0.0330 | 0.0484 | 0.0649 | 0.7951 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 11 | 13 | 0.0123 | 12.27 | 4.870 | 0.3144 | 90.5 | 1065.26 | 14510.9 | 227463 | 0.4586 | 0.1831 | 0.0295 | 0.0009 | 0.1028 | 0.0024 | 0.1962 | 0.0094 | 0.2565 | 0.0319 | 0.2244 | 0.0719 | 0.1268 | 0.1660 | 0.0511 | 0.2677 | 0.0112 | 0.2954 | 0.0016 | 0.1543 | 0.0050 | 0.0000 | 0.0247 | 0.0004 | 0.0691 | 0.0026 | 0.1247 | 0.0146 | 0.1520 | 0.0414 | 0.1628 | 0.1000 | 0.1487 | 0.1803 | 0.1348 | 0.2780 | 0.1782 | 0.3828 | 0.1256 | 0.1981 | 0.1426 | 0.1338 | 0.1343 | 0.1060 | 0.1181 | 0.0730 | 0.1121 | 0.0782 | 0.0895 | 0.0773 | 0.0642 | 0.0695 | 0.0701 | 0.0712 | 0.1434 | 0.1929 | 0.0242 | 0.0702 | 0.1099 | 0.1423 | 0.1381 | 0.1306 | 0.1204 | 0.1069 | 0.1574 |