High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 849 | 648 | | 5112 | 6565 | 125.8 | 31.35 | 178.35 | 174.51 | 89 | 99 | 108 | 116 | 122 | 129 | 138 | 149 | 167 | 0.1097 | 720 | 1.162 | 109.62 | 38.12 | 1 | 0.0534 | 273 | 0.0023 | 21.62 | 6.373 | 0.2588 | 16819.2 | 2390000 | 363000000 | 58800000000 | 0.4232 | 0.2346 | 0.0006 | 0.0000 | 0.0042 | 0.0000 | 0.0130 | 0.0002 | 0.0250 | 0.0036 | 0.0815 | 0.0212 | 0.1644 | 0.0559 | 0.1624 | 0.0520 | 0.1722 | 0.0780 | 0.3765 | 0.7890 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0012 | 0.0000 | 0.0055 | 0.0006 | 0.0352 | 0.0126 | 0.0852 | 0.0358 | 0.0745 | 0.0194 | 0.0985 | 0.0372 | 0.6986 | 0.8945 | 0.0022 | 0.0030 | 0.0087 | 0.0208 | 0.0282 | 0.0653 | 0.1062 | 0.1187 | 0.1593 | 0.1988 | 0.1907 | 0.1691 | 0.1192 | 0.1128 | 0.1148 | 0.0950 | 0.2709 | 0.2166 | 0.0022 | 0.0052 | 0.0108 | 0.0388 | 0.1086 | 0.1483 | 0.1198 | 0.1362 | 0.4302 | 16 | 28 | 49 | 82 | 120 | 170 | 233 | 311 | 426 | 0.0054 | 96.61 | 6.816 | 0.3013 | 62256.2 | 29200000 | 16400000000 | 10300000000000 | 0.4788 | 0.1616 | 0.0394 | 0.0012 | 0.1386 | 0.0088 | 0.2664 | 0.0649 | 0.1673 | 0.1257 | 0.1589 | 0.1784 | 0.1147 | 0.2041 | 0.0514 | 0.1509 | 0.0346 | 0.1222 | 0.0287 | 0.1439 | 0.0000 | 0.0003 | 0.0007 | 0.0000 | 0.0023 | 0.0011 | 0.0171 | 0.0077 | 0.0635 | 0.0541 | 0.1070 | 0.0913 | 0.0846 | 0.0677 | 0.1084 | 0.1006 | 0.6164 | 0.6772 | 0.0009 | 0.0000 | 0.0023 | 0.0028 | 0.0070 | 0.0083 | 0.0232 | 0.0319 | 0.0859 | 0.0979 | 0.1226 | 0.1364 | 0.0878 | 0.0974 | 0.1333 | 0.1320 | 0.5369 | 0.4934 | 0.0008 | 0.0008 | 0.0055 | 0.0169 | 0.0777 | 0.1131 | 0.0868 | 0.1190 | 0.5795 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 97 | 112 | | 5113 | 8192 | 129.9 | 36.86 | 92.19 | 68.78 | 88 | 99 | 108 | 116 | 124 | 132 | 143 | 158 | 180 | 0.0880 | 721 | 0.824 | 96.80 | 28.65 | 1 | 0.0522 | 267 | 0.0018 | 30.75 | 6.658 | 0.2188 | 18224.4 | 2770000 | 455000000 | 80700000000 | 0.4297 | 0.2183 | 0.0015 | 0.0000 | 0.0026 | 0.0000 | 0.0139 | 0.0007 | 0.0530 | 0.0054 | 0.1258 | 0.0349 | 0.1869 | 0.0641 | 0.1767 | 0.0747 | 0.1818 | 0.1217 | 0.2579 | 0.6985 | 0.0008 | 0.0000 | 0.0008 | 0.0000 | 0.0042 | 0.0006 | 0.0117 | 0.0014 | 0.0481 | 0.0188 | 0.0817 | 0.0338 | 0.0838 | 0.0294 | 0.1202 | 0.0555 | 0.6488 | 0.8604 | 0.0063 | 0.0204 | 0.0108 | 0.0102 | 0.0270 | 0.0469 | 0.0685 | 0.1082 | 0.1360 | 0.1837 | 0.1586 | 0.1694 | 0.1342 | 0.1327 | 0.1441 | 0.1449 | 0.3144 | 0.1837 | 0.0014 | 0.0095 | 0.0181 | 0.0443 | 0.0863 | 0.1270 | 0.1116 | 0.1554 | 0.4465 | 24 | 35 | 45 | 57 | 71 | 88 | 114 | 146 | 193 | 0.0043 | 25.07 | 6.144 | 0.3098 | 13228.5 | 2490000 | 551000000 | 137000000000 | 0.5801 | 0.1203 | 0.0269 | 0.0031 | 0.1281 | 0.0165 | 0.2307 | 0.0429 | 0.2162 | 0.1016 | 0.1645 | 0.1799 | 0.1303 | 0.1947 | 0.0604 | 0.1648 | 0.0306 | 0.1384 | 0.0124 | 0.1580 | 0.0018 | 0.0014 | 0.0038 | 0.0038 | 0.0092 | 0.0048 | 0.0272 | 0.0198 | 0.0768 | 0.0577 | 0.1064 | 0.0859 | 0.0913 | 0.0839 | 0.1379 | 0.1141 | 0.5455 | 0.6286 | 0.0008 | 0.0014 | 0.0031 | 0.0058 | 0.0102 | 0.0144 | 0.0403 | 0.0471 | 0.1009 | 0.1215 | 0.1498 | 0.1686 | 0.1139 | 0.1311 | 0.1573 | 0.1662 | 0.4237 | 0.3439 | 0.0022 | 0.0035 | 0.0104 | 0.0371 | 0.0815 | 0.1255 | 0.1107 | 0.1375 | 0.4917 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 619 | 861 | | 3334 | 9894 | 194.2 | 63.45 | 194.29 | 151.46 | 124 | 139 | 154 | 168 | 183 | 201 | 221 | 246 | 280 | 0.0730 | 722 | 0.462 | 118.15 | 25.02 | 1 | 0.1041 | 347 | 0.0006 | 128.05 | 7.588 | 0.1119 | 41739.0 | 9880000 | 2560000000 | 721000000000 | 0.4295 | 0.2204 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0200 | 0.0015 | 0.0524 | 0.0063 | 0.1427 | 0.0431 | 0.1999 | 0.0822 | 0.1730 | 0.0778 | 0.1675 | 0.1202 | 0.2426 | 0.6690 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0039 | 0.0000 | 0.0144 | 0.0039 | 0.0471 | 0.0228 | 0.0781 | 0.0449 | 0.0663 | 0.0308 | 0.0938 | 0.0555 | 0.6958 | 0.8421 | 0.0012 | 0.0050 | 0.0024 | 0.0050 | 0.0060 | 0.0298 | 0.0393 | 0.0720 | 0.1262 | 0.1687 | 0.1738 | 0.1687 | 0.0952 | 0.1092 | 0.1333 | 0.1365 | 0.4226 | 0.3052 | 0.0014 | 0.0014 | 0.0082 | 0.0199 | 0.0694 | 0.1223 | 0.0804 | 0.1154 | 0.5817 | 32 | 63 | 95 | 127 | 160 | 199 | 246 | 304 | 396 | 0.0037 | 29.49 | 6.429 | 0.2958 | 60686.3 | 25300000 | 12900000000 | 7630000000000 | 0.5774 | 0.1179 | 0.0296 | 0.0011 | 0.1266 | 0.0053 | 0.2181 | 0.0429 | 0.1967 | 0.0911 | 0.1622 | 0.1735 | 0.1184 | 0.2026 | 0.0789 | 0.1626 | 0.0488 | 0.1505 | 0.0208 | 0.1703 | 0.0002 | 0.0002 | 0.0010 | 0.0002 | 0.0034 | 0.0016 | 0.0232 | 0.0134 | 0.0774 | 0.0517 | 0.1295 | 0.0963 | 0.1053 | 0.0884 | 0.1348 | 0.1199 | 0.5252 | 0.6283 | 0.0006 | 0.0032 | 0.0043 | 0.0073 | 0.0115 | 0.0218 | 0.0449 | 0.0638 | 0.1172 | 0.1344 | 0.1596 | 0.1707 | 0.1206 | 0.1287 | 0.1522 | 0.1493 | 0.3890 | 0.3208 | 0.0015 | 0.0027 | 0.0089 | 0.0332 | 0.0904 | 0.1524 | 0.1096 | 0.1362 | 0.4652 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 699 | 471 | | 4304 | 9250 | 675.2 | 100.28 | 112.63 | 227.13 | 526 | 609 | 656 | 678 | 694 | 707 | 722 | 740 | 781 | 0.0782 | 723 | 1.058 | 105.04 | 31.11 | 1 | 0.0602 | 259 | 0.0017 | 29.52 | 6.816 | 0.2429 | 465980.0 | 327000000 | 234000000000 | 169000000000000 | 0.4313 | 0.2103 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0028 | 0.0000 | 0.0204 | 0.0139 | 0.0353 | 0.0238 | 0.0311 | 0.0120 | 0.0487 | 0.0205 | 0.8609 | 0.9297 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0149 | 0.0139 | 0.0259 | 0.0238 | 0.0191 | 0.0120 | 0.0254 | 0.0205 | 0.9130 | 0.9297 | 0.0082 | 0.0000 | 0.0163 | 0.0000 | 0.0245 | 0.0000 | 0.0367 | 0.0000 | 0.0816 | 0.0000 | 0.0857 | 0.0000 | 0.0816 | 0.0000 | 0.1143 | 0.0000 | 0.5510 | 0.0000 | 0.0004 | 0.0015 | 0.0038 | 0.0128 | 0.0342 | 0.0556 | 0.0680 | 0.0992 | 0.7244 | 8 | 10 | 12 | 14 | 17 | 26 | 59 | 148 | 341 | 0.1976 | 21.25 | 3.579 | 0.6813 | 64269.9 | 61100000 | 74500000000 | 106000000000000 | 0.4869 | 0.1485 | 0.0430 | 0.0000 | 0.1471 | 0.0171 | 0.1991 | 0.0910 | 0.1222 | 0.1229 | 0.1357 | 0.1456 | 0.1154 | 0.1581 | 0.1086 | 0.1229 | 0.0633 | 0.1024 | 0.0656 | 0.2400 | 0.0000 | 0.0000 | 0.0008 | 0.0004 | 0.0013 | 0.0011 | 0.0109 | 0.0094 | 0.0419 | 0.0410 | 0.0747 | 0.0556 | 0.0516 | 0.0402 | 0.0763 | 0.0676 | 0.7425 | 0.7847 | 0.0000 | 0.0006 | 0.0010 | 0.0022 | 0.0031 | 0.0028 | 0.0175 | 0.0185 | 0.0577 | 0.0612 | 0.0911 | 0.1021 | 0.0695 | 0.0606 | 0.0901 | 0.0948 | 0.6699 | 0.6571 | 0.0000 | 0.0009 | 0.0032 | 0.0125 | 0.0529 | 0.0779 | 0.0682 | 0.0904 | 0.6939 | ||
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1110 | 757 | | 3351 | 8311 | 502.7 | 95.67 | 33.73 | 39.62 | 357 | 407 | 453 | 492 | 521 | 545 | 571 | 592 | 615 | 0.0870 | 723 | 0.586 | 94.34 | 18.44 | 4 | 0.0800 | 268 | 0.0017 | 22.52 | 6.640 | 0.2618 | 261823.0 | 140000000 | 77100000000 | 43100000000000 | 0.4208 | 0.2054 | 0.0009 | 0.0000 | 0.0018 | 0.0000 | 0.0032 | 0.0000 | 0.0126 | 0.0003 | 0.0519 | 0.0230 | 0.0992 | 0.0385 | 0.0767 | 0.0212 | 0.1164 | 0.0333 | 0.6373 | 0.8836 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0033 | 0.0003 | 0.0258 | 0.0230 | 0.0508 | 0.0385 | 0.0309 | 0.0212 | 0.0416 | 0.0333 | 0.8475 | 0.8836 | 0.0040 | 0.0000 | 0.0100 | 0.0000 | 0.0562 | 0.0000 | 0.0462 | 0.0000 | 0.0884 | 0.0000 | 0.1486 | 0.0000 | 0.1245 | 0.0000 | 0.1365 | 0.0000 | 0.3855 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0105 | 0.0374 | 0.0664 | 0.0485 | 0.0822 | 0.7533 | 6 | 9 | 12 | 17 | 22 | 27 | 35 | 48 | 73 | 0.0559 | 2.46 | 3.830 | 0.6657 | 2706.9 | 419279 | 98900000 | 30200000000 | 0.4904 | 0.1617 | 0.0258 | 0.0068 | 0.0646 | 0.0188 | 0.1025 | 0.0315 | 0.1291 | 0.0630 | 0.1646 | 0.0926 | 0.1542 | 0.1197 | 0.1703 | 0.1268 | 0.1219 | 0.1707 | 0.0670 | 0.3702 | 0.0043 | 0.0037 | 0.0109 | 0.0089 | 0.0173 | 0.0103 | 0.0261 | 0.0233 | 0.0480 | 0.0423 | 0.0690 | 0.0618 | 0.0693 | 0.0622 | 0.0976 | 0.0913 | 0.6574 | 0.6962 | 0.0015 | 0.0023 | 0.0102 | 0.0059 | 0.0171 | 0.0147 | 0.0297 | 0.0282 | 0.0585 | 0.0639 | 0.0848 | 0.0886 | 0.0692 | 0.0745 | 0.1053 | 0.1003 | 0.6236 | 0.6217 | 0.0050 | 0.0123 | 0.0204 | 0.0316 | 0.0500 | 0.0750 | 0.0685 | 0.0927 | 0.6445 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 469 | 438 | | 2983 | 6904 | 291.5 | 155.73 | 25.80 | 36.51 | 163 | 179 | 192 | 210 | 232 | 259 | 292 | 423 | 579 | 0.1047 | 723 | 0.563 | 78.24 | 21.26 | 5 | 0.0865 | 258 | 0.0031 | 12.41 | 6.310 | 0.3653 | 109220.0 | 50500000 | 26800000000 | 15300000000000 | 0.4115 | 0.2245 | 0.0013 | 0.0000 | 0.0013 | 0.0011 | 0.0053 | 0.0049 | 0.0279 | 0.0152 | 0.0810 | 0.0455 | 0.1514 | 0.0829 | 0.1142 | 0.0650 | 0.1116 | 0.0861 | 0.5060 | 0.6994 | 0.0007 | 0.0000 | 0.0007 | 0.0008 | 0.0027 | 0.0036 | 0.0129 | 0.0101 | 0.0278 | 0.0283 | 0.0394 | 0.0449 | 0.0455 | 0.0377 | 0.0502 | 0.0494 | 0.8201 | 0.8251 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0048 | 0.0250 | 0.0353 | 0.0722 | 0.0609 | 0.0222 | 0.0304 | 0.0431 | 0.0529 | 0.8333 | 0.8157 | 0.0000 | 0.0022 | 0.0078 | 0.0100 | 0.0288 | 0.0654 | 0.0310 | 0.0488 | 0.8060 | 7 | 9 | 10 | 12 | 14 | 17 | 22 | 30 | 49 | 0.1051 | 1.66 | 3.110 | 0.7374 | 1998.1 | 320182 | 69200000 | 17600000000 | 0.5249 | 0.1326 | 0.0229 | 0.0158 | 0.0439 | 0.0273 | 0.0768 | 0.0379 | 0.1286 | 0.0532 | 0.1655 | 0.0873 | 0.1864 | 0.1237 | 0.1685 | 0.1324 | 0.1256 | 0.1938 | 0.0818 | 0.3285 | 0.0053 | 0.0100 | 0.0107 | 0.0158 | 0.0191 | 0.0197 | 0.0364 | 0.0262 | 0.0631 | 0.0494 | 0.1039 | 0.0862 | 0.0795 | 0.0733 | 0.0955 | 0.1172 | 0.5866 | 0.6021 | 0.0056 | 0.0129 | 0.0104 | 0.0069 | 0.0288 | 0.0247 | 0.0400 | 0.0366 | 0.0737 | 0.0791 | 0.1017 | 0.1098 | 0.0745 | 0.0692 | 0.1129 | 0.0930 | 0.5524 | 0.5678 | 0.0070 | 0.0152 | 0.0275 | 0.0427 | 0.0719 | 0.1029 | 0.0830 | 0.0918 | 0.5582 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 917 | 765 | | 4787 | 6025 | 134.0 | 29.36 | 199.47 | 144.31 | 101 | 111 | 117 | 124 | 130 | 137 | 145 | 154 | 168 | 0.1200 | 723 | 1.159 | 112.49 | 39.01 | 1 | 0.0570 | 273 | 0.0026 | 20.01 | 6.253 | 0.2547 | 18810.6 | 2780000 | 434000000 | 72000000000 | 0.4427 | 0.2093 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0064 | 0.0013 | 0.0155 | 0.0016 | 0.0709 | 0.0202 | 0.1267 | 0.0377 | 0.1506 | 0.0388 | 0.1815 | 0.0566 | 0.4467 | 0.8438 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0073 | 0.0004 | 0.0405 | 0.0149 | 0.0653 | 0.0246 | 0.0710 | 0.0181 | 0.0965 | 0.0305 | 0.7169 | 0.9114 | 0.0043 | 0.0000 | 0.0157 | 0.0082 | 0.0443 | 0.0286 | 0.0944 | 0.1224 | 0.1688 | 0.1510 | 0.1574 | 0.2041 | 0.0987 | 0.1102 | 0.1273 | 0.1224 | 0.2890 | 0.2531 | 0.0018 | 0.0042 | 0.0125 | 0.0365 | 0.0983 | 0.1347 | 0.1117 | 0.1440 | 0.4564 | 44 | 68 | 100 | 134 | 171 | 211 | 256 | 309 | 392 | 0.0015 | 70.67 | 7.066 | 0.2195 | 60610.6 | 23900000 | 11300000000 | 6160000000000 | 0.5305 | 0.1272 | 0.0202 | 0.0004 | 0.0960 | 0.0047 | 0.2098 | 0.0436 | 0.2030 | 0.0781 | 0.1955 | 0.1872 | 0.1348 | 0.1919 | 0.0851 | 0.1725 | 0.0447 | 0.1552 | 0.0110 | 0.1665 | 0.0006 | 0.0003 | 0.0009 | 0.0005 | 0.0019 | 0.0026 | 0.0206 | 0.0127 | 0.0768 | 0.0560 | 0.1070 | 0.0915 | 0.0989 | 0.0710 | 0.1385 | 0.1099 | 0.5548 | 0.6556 | 0.0015 | 0.0032 | 0.0064 | 0.0097 | 0.0124 | 0.0175 | 0.0500 | 0.0662 | 0.1199 | 0.1364 | 0.1640 | 0.1857 | 0.1189 | 0.1422 | 0.1690 | 0.1513 | 0.3578 | 0.2877 | 0.0008 | 0.0008 | 0.0077 | 0.0291 | 0.0926 | 0.1403 | 0.1170 | 0.1592 | 0.4525 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 900 | 171 | | 3930 | 11298 | 497.7 | 103.96 | 94.40 | 173.19 | 316 | 409 | 476 | 500 | 521 | 540 | 560 | 583 | 613 | 0.0641 | 724 | 0.847 | 112.54 | 33.02 | 4 | 0.0832 | 327 | 0.0011 | 32.58 | 7.096 | 0.2211 | 258499.0 | 139000000 | 76000000000 | 42400000000000 | 0.3874 | 0.2511 | 0.0008 | 0.0003 | 0.0015 | 0.0000 | 0.0057 | 0.0000 | 0.0069 | 0.0008 | 0.0413 | 0.0186 | 0.0462 | 0.0251 | 0.0569 | 0.0178 | 0.0810 | 0.0276 | 0.7597 | 0.9099 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0197 | 0.0186 | 0.0188 | 0.0251 | 0.0172 | 0.0178 | 0.0260 | 0.0276 | 0.9179 | 0.9099 | 0.0052 | 0.0000 | 0.0140 | 0.0000 | 0.0315 | 0.0000 | 0.0542 | 0.0000 | 0.0717 | 0.0000 | 0.0944 | 0.0000 | 0.1119 | 0.0000 | 0.1556 | 0.0000 | 0.4615 | 0.0000 | 0.0012 | 0.0042 | 0.0037 | 0.0108 | 0.0279 | 0.0396 | 0.0500 | 0.0629 | 0.7997 | 6 | 7 | 9 | 10 | 14 | 24 | 52 | 125 | 339 | 0.1266 | 21.37 | 4.235 | 0.6154 | 38902.8 | 22700000 | 15400000000 | 11500000000000 | 0.5106 | 0.1373 | 0.0416 | 0.0018 | 0.1323 | 0.0210 | 0.2420 | 0.0602 | 0.1739 | 0.1267 | 0.1815 | 0.2124 | 0.1361 | 0.2042 | 0.0586 | 0.1258 | 0.0265 | 0.1167 | 0.0076 | 0.1313 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0031 | 0.0015 | 0.0097 | 0.0106 | 0.0497 | 0.0439 | 0.0660 | 0.0569 | 0.0453 | 0.0375 | 0.0729 | 0.0623 | 0.7530 | 0.7860 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0013 | 0.0018 | 0.0139 | 0.0172 | 0.0499 | 0.0548 | 0.0820 | 0.0743 | 0.0465 | 0.0535 | 0.0714 | 0.0729 | 0.7342 | 0.7254 | 0.0008 | 0.0000 | 0.0015 | 0.0131 | 0.0528 | 0.0670 | 0.0466 | 0.0751 | 0.7432 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 637 | 251 | | 4831 | 6157 | 434.9 | 144.34 | 87.99 | 128.76 | 226 | 293 | 353 | 413 | 455 | 489 | 520 | 554 | 622 | 0.1176 | 724 | 0.741 | 143.63 | 44.91 | 2 | 0.0909 | 439 | 0.0009 | 28.38 | 7.266 | 0.2359 | 209951.0 | 109000000 | 59200000000 | 33500000000000 | 0.3927 | 0.2352 | 0.0015 | 0.0000 | 0.0035 | 0.0000 | 0.0050 | 0.0003 | 0.0179 | 0.0042 | 0.0601 | 0.0282 | 0.1118 | 0.0434 | 0.0860 | 0.0299 | 0.1143 | 0.0511 | 0.5999 | 0.8429 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0002 | 0.0023 | 0.0022 | 0.0216 | 0.0210 | 0.0347 | 0.0259 | 0.0213 | 0.0213 | 0.0361 | 0.0291 | 0.8835 | 0.9002 | 0.0007 | 0.0000 | 0.0035 | 0.0000 | 0.0084 | 0.0000 | 0.0169 | 0.0000 | 0.0443 | 0.0000 | 0.0718 | 0.0000 | 0.0577 | 0.0000 | 0.0809 | 0.0000 | 0.7157 | 1.0000 | 0.0000 | 0.0007 | 0.0011 | 0.0048 | 0.0257 | 0.0432 | 0.0313 | 0.0555 | 0.8375 | 9 | 11 | 13 | 18 | 26 | 42 | 87 | 147 | 262 | 0.1247 | 11.17 | 3.769 | 0.6386 | 24317.8 | 10200000 | 5220000000 | 3080000000000 | 0.5729 | 0.1008 | 0.0398 | 0.0089 | 0.1273 | 0.0316 | 0.1777 | 0.0671 | 0.1751 | 0.0886 | 0.1565 | 0.1696 | 0.1008 | 0.1810 | 0.0955 | 0.1405 | 0.0822 | 0.1329 | 0.0451 | 0.1797 | 0.0005 | 0.0004 | 0.0020 | 0.0027 | 0.0025 | 0.0027 | 0.0094 | 0.0093 | 0.0480 | 0.0409 | 0.0762 | 0.0721 | 0.0574 | 0.0503 | 0.0826 | 0.0730 | 0.7216 | 0.7486 | 0.0000 | 0.0007 | 0.0018 | 0.0000 | 0.0030 | 0.0048 | 0.0152 | 0.0213 | 0.0626 | 0.0810 | 0.1027 | 0.1071 | 0.0699 | 0.1009 | 0.1240 | 0.1263 | 0.6207 | 0.5580 | 0.0000 | 0.0005 | 0.0016 | 0.0114 | 0.0565 | 0.0864 | 0.0549 | 0.1010 | 0.6877 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1189 | 733 | | 6368 | 8540 | 460.5 | 95.33 | 276.86 | 365.75 | 341 | 370 | 398 | 426 | 449 | 474 | 509 | 550 | 597 | 0.0848 | 724 | 0.776 | 177.72 | 41.62 | 1 | 0.0785 | 500 | 0.0009 | 23.98 | 7.222 | 0.2306 | 221183.0 | 111000000 | 57400000000 | 30900000000000 | 0.4039 | 0.2350 | 0.0005 | 0.0000 | 0.0020 | 0.0003 | 0.0059 | 0.0005 | 0.0136 | 0.0018 | 0.0358 | 0.0143 | 0.0491 | 0.0278 | 0.0573 | 0.0203 | 0.0893 | 0.0345 | 0.7465 | 0.9005 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0021 | 0.0000 | 0.0072 | 0.0005 | 0.0145 | 0.0099 | 0.0191 | 0.0206 | 0.0217 | 0.0093 | 0.0320 | 0.0179 | 0.9023 | 0.9419 | 0.0074 | 0.0186 | 0.0017 | 0.0372 | 0.0124 | 0.0558 | 0.0314 | 0.0884 | 0.0553 | 0.1023 | 0.0677 | 0.1395 | 0.0619 | 0.1302 | 0.0958 | 0.1535 | 0.6664 | 0.2744 | 0.0003 | 0.0024 | 0.0069 | 0.0180 | 0.0340 | 0.0506 | 0.0544 | 0.0634 | 0.7698 | 9 | 12 | 16 | 59 | 118 | 196 | 330 | 523 | 797 | 0.0654 | 101.98 | 5.746 | 0.4428 | 210404.0 | 226000000 | 301000000000 | 467000000000000 | 0.4431 | 0.2080 | 0.0250 | 0.0028 | 0.1591 | 0.0106 | 0.2872 | 0.0700 | 0.1944 | 0.1272 | 0.1399 | 0.1965 | 0.1046 | 0.2367 | 0.0442 | 0.1357 | 0.0339 | 0.1074 | 0.0118 | 0.1131 | 0.0000 | 0.0000 | 0.0006 | 0.0011 | 0.0028 | 0.0030 | 0.0130 | 0.0116 | 0.0551 | 0.0462 | 0.0740 | 0.0648 | 0.0688 | 0.0562 | 0.0988 | 0.0759 | 0.6869 | 0.7413 | 0.0008 | 0.0004 | 0.0016 | 0.0026 | 0.0035 | 0.0044 | 0.0208 | 0.0219 | 0.0631 | 0.0804 | 0.1145 | 0.1307 | 0.0922 | 0.0979 | 0.1196 | 0.1281 | 0.5839 | 0.5337 | 0.0000 | 0.0011 | 0.0032 | 0.0151 | 0.0601 | 0.0984 | 0.0766 | 0.1131 | 0.6325 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 680 | 551 | | 5987 | 6093 | 134.6 | 38.08 | 176.05 | 235.22 | 92 | 104 | 113 | 122 | 129 | 138 | 148 | 161 | 182 | 0.1188 | 724 | 1.000 | 95.60 | 29.27 | 1 | 0.0403 | 241 | 0.0020 | 24.09 | 6.532 | 0.2581 | 19556.5 | 3090000 | 540000000 | 105000000000 | 0.4491 | 0.2026 | 0.0006 | 0.0000 | 0.0035 | 0.0004 | 0.0088 | 0.0006 | 0.0253 | 0.0021 | 0.0823 | 0.0225 | 0.1531 | 0.0497 | 0.1611 | 0.0584 | 0.1743 | 0.0871 | 0.3909 | 0.7792 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0031 | 0.0000 | 0.0090 | 0.0005 | 0.0374 | 0.0132 | 0.0593 | 0.0258 | 0.0654 | 0.0231 | 0.0842 | 0.0390 | 0.7408 | 0.8984 | 0.0009 | 0.0104 | 0.0128 | 0.0084 | 0.0239 | 0.0251 | 0.0632 | 0.0898 | 0.1376 | 0.1962 | 0.1709 | 0.1649 | 0.1043 | 0.1211 | 0.1564 | 0.1608 | 0.3299 | 0.2234 | 0.0023 | 0.0023 | 0.0095 | 0.0338 | 0.0834 | 0.1244 | 0.1085 | 0.1301 | 0.5059 | 10 | 11 | 13 | 16 | 34 | 115 | 229 | 352 | 553 | 0.1116 | 42.16 | 4.818 | 0.5374 | 86309.7 | 54700000 | 39600000000 | 31400000000000 | 0.5384 | 0.1532 | 0.0884 | 0.0052 | 0.2601 | 0.0551 | 0.2652 | 0.1627 | 0.1288 | 0.1890 | 0.0833 | 0.2008 | 0.0758 | 0.1444 | 0.0581 | 0.0866 | 0.0227 | 0.0735 | 0.0177 | 0.0827 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0020 | 0.0121 | 0.0068 | 0.0484 | 0.0419 | 0.0963 | 0.0971 | 0.0652 | 0.0532 | 0.0963 | 0.0789 | 0.6799 | 0.7201 | 0.0000 | 0.0006 | 0.0016 | 0.0017 | 0.0021 | 0.0058 | 0.0172 | 0.0221 | 0.0667 | 0.0813 | 0.1199 | 0.1371 | 0.0896 | 0.0936 | 0.1214 | 0.1174 | 0.5816 | 0.5404 | 0.0000 | 0.0014 | 0.0023 | 0.0136 | 0.0567 | 0.1068 | 0.0829 | 0.1036 | 0.6326 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 762 | 189 | | 1376 | 10419 | 35.3 | 9.21 | 10.27 | 5.63 | 22 | 26 | 29 | 33 | 36 | 39 | 42 | 44 | 47 | 0.0696 | 725 | 0.931 | 32.02 | 6.00 | 6 | 0.0509 | 70 | 0.0514 | 0.71 | 3.174 | 0.7185 | 1329.9 | 52792.9 | 2180000 | 92900000 | 0.3888 | 0.2401 | 0.0112 | 0.0000 | 0.0224 | 0.0000 | 0.0384 | 0.0041 | 0.0480 | 0.0132 | 0.0880 | 0.0438 | 0.1296 | 0.0661 | 0.1552 | 0.0867 | 0.2224 | 0.1189 | 0.2848 | 0.6672 | 0.0038 | 0.0000 | 0.0029 | 0.0000 | 0.0105 | 0.0023 | 0.0134 | 0.0077 | 0.0335 | 0.0302 | 0.0374 | 0.0294 | 0.0412 | 0.0394 | 0.0766 | 0.0510 | 0.7807 | 0.8399 | 0.0167 | 0.0854 | 0.0143 | 0.1707 | 0.0263 | 0.1341 | 0.0430 | 0.2073 | 0.0740 | 0.1463 | 0.0883 | 0.2073 | 0.0931 | 0.0244 | 0.1551 | 0.0244 | 0.4893 | 0.0000 | 0.0027 | 0.0040 | 0.0121 | 0.0214 | 0.0429 | 0.0402 | 0.0657 | 0.0979 | 0.7131 | 5 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 15 | 0.2596 | 0.30 | 0.975 | 0.6174 | 137.1 | 3359.17 | 189453 | 16100000 | 0.5305 | 0.1486 | 0.0352 | 0.0019 | 0.0945 | 0.0122 | 0.1668 | 0.0289 | 0.2222 | 0.0571 | 0.2112 | 0.0964 | 0.1536 | 0.1503 | 0.0877 | 0.2161 | 0.0244 | 0.2552 | 0.0044 | 0.1819 | 0.0068 | 0.0000 | 0.0230 | 0.0021 | 0.0437 | 0.0082 | 0.0549 | 0.0212 | 0.0735 | 0.0449 | 0.0787 | 0.0675 | 0.1107 | 0.0939 | 0.1744 | 0.1513 | 0.4343 | 0.6109 | 0.0472 | 0.0923 | 0.0513 | 0.1077 | 0.0808 | 0.1294 | 0.1073 | 0.1464 | 0.1292 | 0.1422 | 0.1429 | 0.1316 | 0.1703 | 0.1167 | 0.1551 | 0.0716 | 0.1158 | 0.0621 | 0.0303 | 0.0432 | 0.0455 | 0.0586 | 0.0760 | 0.1103 | 0.1403 | 0.2192 | 0.2767 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 994 | 366 | | 5578 | 9502 | 439.0 | 109.23 | 7.27 | 7.81 | 292 | 342 | 380 | 410 | 440 | 471 | 499 | 532 | 577 | 0.0764 | 726 | 0.939 | 87.10 | 28.18 | 1 | 0.0446 | 249 | 0.0007 | 54.37 | 7.463 | 0.1610 | 204683.0 | 101000000 | 51800000000 | 27900000000000 | 0.4190 | 0.2212 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0035 | 0.0004 | 0.0227 | 0.0026 | 0.0796 | 0.0200 | 0.1332 | 0.0381 | 0.1486 | 0.0495 | 0.1674 | 0.0707 | 0.4438 | 0.8187 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0009 | 0.0004 | 0.0055 | 0.0021 | 0.0249 | 0.0145 | 0.0386 | 0.0203 | 0.0420 | 0.0202 | 0.0598 | 0.0259 | 0.8277 | 0.9167 | 0.0025 | 0.0150 | 0.0083 | 0.0300 | 0.0108 | 0.0936 | 0.0717 | 0.1685 | 0.1350 | 0.1648 | 0.1983 | 0.1985 | 0.1250 | 0.0749 | 0.1433 | 0.0599 | 0.3050 | 0.1948 | 0.0011 | 0.0014 | 0.0018 | 0.0164 | 0.0513 | 0.0969 | 0.0840 | 0.1033 | 0.6439 | 3 | 4 | 5 | 6 | 6 | 7 | 8 | 8 | 10 | 0.3430 | 0.51 | 1.198 | 0.7294 | 113.9 | 6884.51 | 785459 | 106000000 | 0.5832 | 0.1225 | 0.0192 | 0.0019 | 0.0770 | 0.0156 | 0.1579 | 0.0462 | 0.2263 | 0.1039 | 0.2280 | 0.1979 | 0.1695 | 0.2473 | 0.0885 | 0.2176 | 0.0290 | 0.1308 | 0.0047 | 0.0389 | 0.0061 | 0.0001 | 0.0245 | 0.0052 | 0.0678 | 0.0214 | 0.1121 | 0.0524 | 0.1595 | 0.1246 | 0.1671 | 0.1799 | 0.1649 | 0.2137 | 0.1572 | 0.2103 | 0.1408 | 0.1925 | 0.1745 | 0.1950 | 0.1707 | 0.1376 | 0.1329 | 0.1217 | 0.1097 | 0.1088 | 0.0929 | 0.0945 | 0.0843 | 0.0801 | 0.0659 | 0.0748 | 0.0751 | 0.0786 | 0.0940 | 0.1088 | 0.0231 | 0.0695 | 0.1299 | 0.1560 | 0.1619 | 0.1493 | 0.1157 | 0.0965 | 0.0981 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 665 | 315 | | 3881 | 7921 | 606.2 | 94.41 | 68.43 | 170.19 | 472 | 541 | 568 | 588 | 606 | 629 | 660 | 694 | 726 | 0.0917 | 726 | 0.976 | 112.07 | 42.38 | 2 | 0.0825 | 320 | 0.0014 | 32.18 | 6.910 | 0.2353 | 376420.0 | 239000000 | 154000000000 | 101000000000000 | 0.4392 | 0.1933 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0052 | 0.0005 | 0.0345 | 0.0169 | 0.0495 | 0.0301 | 0.0505 | 0.0161 | 0.0697 | 0.0270 | 0.7890 | 0.9095 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0005 | 0.0212 | 0.0169 | 0.0256 | 0.0301 | 0.0206 | 0.0161 | 0.0317 | 0.0270 | 0.8986 | 0.9095 | 0.0054 | 0.0000 | 0.0161 | 0.0000 | 0.0215 | 0.0000 | 0.0538 | 0.0000 | 0.1048 | 0.0000 | 0.1532 | 0.0000 | 0.1183 | 0.0000 | 0.1263 | 0.0000 | 0.4005 | 0.0000 | 0.0031 | 0.0031 | 0.0097 | 0.0219 | 0.0429 | 0.0566 | 0.0536 | 0.0929 | 0.7163 | 5 | 6 | 7 | 9 | 10 | 11 | 14 | 30 | 209 | 0.1903 | 6.63 | 2.602 | 0.6219 | 33642.3 | 23500000 | 18600000000 | 16100000000000 | 0.5469 | 0.1234 | 0.0143 | 0.0118 | 0.2071 | 0.0059 | 0.2500 | 0.0710 | 0.2357 | 0.1154 | 0.2571 | 0.2308 | 0.0286 | 0.2337 | 0.0071 | 0.1834 | 0.0000 | 0.1065 | 0.0000 | 0.0414 | 0.0000 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0050 | 0.0119 | 0.0114 | 0.0500 | 0.0456 | 0.0738 | 0.0777 | 0.0484 | 0.0428 | 0.0745 | 0.0720 | 0.7407 | 0.7418 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0009 | 0.0089 | 0.0132 | 0.0526 | 0.0545 | 0.0847 | 0.0771 | 0.0455 | 0.0526 | 0.0794 | 0.0808 | 0.7279 | 0.7209 | 0.0000 | 0.0000 | 0.0017 | 0.0093 | 0.0499 | 0.0854 | 0.0448 | 0.0761 | 0.7327 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 781 | 933 | | 4650 | 7671 | 149.2 | 35.80 | 272.55 | 157.57 | 110 | 120 | 127 | 134 | 142 | 151 | 162 | 176 | 198 | 0.0948 | 727 | 1.075 | 97.75 | 27.80 | 1 | 0.0520 | 242 | 0.0020 | 26.81 | 6.558 | 0.2363 | 23531.1 | 3940000 | 699000000 | 132000000000 | 0.4493 | 0.1999 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0104 | 0.0002 | 0.0338 | 0.0009 | 0.0898 | 0.0243 | 0.1628 | 0.0471 | 0.1597 | 0.0468 | 0.1837 | 0.0695 | 0.3577 | 0.8111 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0002 | 0.0118 | 0.0004 | 0.0454 | 0.0150 | 0.0668 | 0.0232 | 0.0778 | 0.0163 | 0.1088 | 0.0306 | 0.6864 | 0.9142 | 0.0023 | 0.0030 | 0.0092 | 0.0060 | 0.0358 | 0.0329 | 0.0796 | 0.0928 | 0.1476 | 0.1707 | 0.1857 | 0.2335 | 0.1153 | 0.1138 | 0.1361 | 0.1707 | 0.2884 | 0.1766 | 0.0020 | 0.0035 | 0.0111 | 0.0308 | 0.0968 | 0.1402 | 0.1160 | 0.1452 | 0.4544 | 91 | 134 | 171 | 208 | 247 | 291 | 338 | 395 | 486 | 0.0007 | 96.75 | 7.538 | 0.1758 | 99105.9 | 44100000 | 22800000000 | 13300000000000 | 0.5485 | 0.1214 | 0.0151 | 0.0008 | 0.0764 | 0.0058 | 0.1871 | 0.0233 | 0.1861 | 0.0595 | 0.2027 | 0.1375 | 0.1554 | 0.2135 | 0.0941 | 0.1857 | 0.0520 | 0.1666 | 0.0312 | 0.2074 | 0.0009 | 0.0002 | 0.0030 | 0.0007 | 0.0077 | 0.0036 | 0.0219 | 0.0100 | 0.0743 | 0.0552 | 0.1272 | 0.1019 | 0.1078 | 0.0886 | 0.1429 | 0.1166 | 0.5144 | 0.6232 | 0.0008 | 0.0053 | 0.0106 | 0.0148 | 0.0203 | 0.0373 | 0.0519 | 0.0841 | 0.1339 | 0.1587 | 0.1729 | 0.1829 | 0.1303 | 0.1533 | 0.1652 | 0.1385 | 0.3141 | 0.2250 | 0.0009 | 0.0051 | 0.0146 | 0.0363 | 0.0991 | 0.1479 | 0.1303 | 0.1511 | 0.4148 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1111 | 520 | | 5855 | 6285 | 143.7 | 37.71 | 129.84 | 96.11 | 100 | 111 | 121 | 130 | 139 | 148 | 159 | 173 | 193 | 0.1158 | 728 | 1.106 | 84.72 | 30.89 | 1 | 0.0386 | 226 | 0.0018 | 22.88 | 6.593 | 0.2522 | 22082.0 | 3630000 | 639000000 | 120000000000 | 0.4079 | 0.2384 | 0.0012 | 0.0000 | 0.0012 | 0.0000 | 0.0053 | 0.0009 | 0.0273 | 0.0032 | 0.0825 | 0.0265 | 0.1384 | 0.0467 | 0.1437 | 0.0495 | 0.1713 | 0.0767 | 0.4291 | 0.7964 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0023 | 0.0007 | 0.0111 | 0.0024 | 0.0330 | 0.0159 | 0.0489 | 0.0238 | 0.0561 | 0.0196 | 0.0820 | 0.0283 | 0.7655 | 0.9092 | 0.0051 | 0.0118 | 0.0093 | 0.0212 | 0.0144 | 0.0259 | 0.0433 | 0.1108 | 0.1155 | 0.1769 | 0.1606 | 0.1792 | 0.1189 | 0.1321 | 0.1589 | 0.1179 | 0.3738 | 0.2241 | 0.0000 | 0.0026 | 0.0098 | 0.0298 | 0.0706 | 0.1009 | 0.1024 | 0.1220 | 0.5618 | 32 | 50 | 66 | 81 | 103 | 128 | 163 | 209 | 265 | 0.0036 | 23.50 | 6.280 | 0.3297 | 26095.3 | 6930000 | 2240000000 | 849000000000 | 0.5029 | 0.1525 | 0.0154 | 0.0026 | 0.0867 | 0.0100 | 0.1762 | 0.0374 | 0.1734 | 0.0756 | 0.1861 | 0.1538 | 0.1463 | 0.2112 | 0.0976 | 0.1556 | 0.0623 | 0.1460 | 0.0560 | 0.2077 | 0.0013 | 0.0013 | 0.0035 | 0.0021 | 0.0061 | 0.0080 | 0.0218 | 0.0157 | 0.0609 | 0.0519 | 0.0984 | 0.0855 | 0.0853 | 0.0703 | 0.1093 | 0.0883 | 0.6133 | 0.6770 | 0.0010 | 0.0013 | 0.0030 | 0.0088 | 0.0075 | 0.0157 | 0.0293 | 0.0452 | 0.0974 | 0.1129 | 0.1546 | 0.1763 | 0.1133 | 0.1129 | 0.1362 | 0.1412 | 0.4578 | 0.3858 | 0.0004 | 0.0036 | 0.0101 | 0.0222 | 0.0677 | 0.1431 | 0.0879 | 0.1278 | 0.5371 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 412 | 164 | | 5214 | 3654 | 127.8 | 31.45 | 127.02 | 119.19 | 94 | 101 | 108 | 114 | 122 | 130 | 140 | 152 | 171 | 0.1992 | 728 | 1.004 | 82.88 | 29.02 | 1 | 0.0410 | 214 | 0.0025 | 19.85 | 6.334 | 0.2553 | 17320.5 | 2500000 | 383000000 | 62600000000 | 0.4259 | 0.2172 | 0.0000 | 0.0000 | 0.0033 | 0.0004 | 0.0102 | 0.0015 | 0.0302 | 0.0023 | 0.0973 | 0.0197 | 0.1795 | 0.0519 | 0.1558 | 0.0471 | 0.1926 | 0.0952 | 0.3310 | 0.7820 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0000 | 0.0154 | 0.0010 | 0.0426 | 0.0123 | 0.0753 | 0.0280 | 0.0688 | 0.0178 | 0.1065 | 0.0382 | 0.6871 | 0.9028 | 0.0040 | 0.0138 | 0.0030 | 0.0165 | 0.0191 | 0.0579 | 0.0702 | 0.1377 | 0.1484 | 0.1791 | 0.1856 | 0.1983 | 0.1414 | 0.1157 | 0.1585 | 0.1267 | 0.2698 | 0.1543 | 0.0013 | 0.0018 | 0.0107 | 0.0360 | 0.0821 | 0.1256 | 0.1087 | 0.1429 | 0.4909 | 21 | 28 | 40 | 58 | 85 | 123 | 162 | 215 | 293 | 0.0076 | 41.14 | 6.126 | 0.3286 | 30335.5 | 10000000 | 4000000000 | 1810000000000 | 0.5437 | 0.1217 | 0.0721 | 0.0000 | 0.1943 | 0.0489 | 0.2183 | 0.0915 | 0.1550 | 0.1362 | 0.1288 | 0.2152 | 0.1070 | 0.2152 | 0.0699 | 0.1060 | 0.0393 | 0.0925 | 0.0153 | 0.0946 | 0.0006 | 0.0000 | 0.0055 | 0.0067 | 0.0079 | 0.0052 | 0.0286 | 0.0202 | 0.0930 | 0.0802 | 0.1471 | 0.1397 | 0.0942 | 0.0874 | 0.1204 | 0.1231 | 0.5027 | 0.5375 | 0.0008 | 0.0031 | 0.0059 | 0.0041 | 0.0110 | 0.0113 | 0.0505 | 0.0515 | 0.1112 | 0.1308 | 0.1457 | 0.1740 | 0.1053 | 0.1174 | 0.1314 | 0.1349 | 0.4381 | 0.3728 | 0.0007 | 0.0049 | 0.0133 | 0.0379 | 0.1011 | 0.1517 | 0.0962 | 0.1187 | 0.4754 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1249 | 769 | | 4803 | 11247 | 502.2 | 83.00 | 67.05 | 122.38 | 382 | 431 | 463 | 488 | 508 | 528 | 552 | 579 | 608 | 0.0648 | 729 | 1.156 | 88.46 | 33.06 | 1 | 0.0477 | 229 | 0.0014 | 23.98 | 6.830 | 0.2358 | 259094.0 | 137000000 | 73800000000 | 40500000000000 | 0.4284 | 0.2133 | 0.0011 | 0.0000 | 0.0019 | 0.0000 | 0.0044 | 0.0000 | 0.0091 | 0.0002 | 0.0299 | 0.0136 | 0.0517 | 0.0206 | 0.0575 | 0.0124 | 0.0811 | 0.0183 | 0.7632 | 0.9350 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0002 | 0.0170 | 0.0136 | 0.0276 | 0.0206 | 0.0218 | 0.0124 | 0.0377 | 0.0183 | 0.8937 | 0.9350 | 0.0072 | 0.0000 | 0.0181 | 0.0000 | 0.0325 | 0.0000 | 0.0597 | 0.0000 | 0.0868 | 0.0000 | 0.1374 | 0.0000 | 0.1230 | 0.0000 | 0.1754 | 0.0000 | 0.3599 | 0.0000 | 0.0019 | 0.0016 | 0.0054 | 0.0140 | 0.0384 | 0.0594 | 0.0602 | 0.0889 | 0.7301 | 6 | 8 | 10 | 12 | 15 | 20 | 38 | 86 | 207 | 0.1665 | 6.51 | 3.350 | 0.6502 | 19470.7 | 8860000 | 4860000000 | 2970000000000 | 0.5816 | 0.0962 | 0.0324 | 0.0043 | 0.1477 | 0.0208 | 0.2216 | 0.0720 | 0.2090 | 0.1276 | 0.1658 | 0.1753 | 0.1189 | 0.1840 | 0.0613 | 0.1372 | 0.0216 | 0.1345 | 0.0216 | 0.1441 | 0.0007 | 0.0003 | 0.0010 | 0.0009 | 0.0034 | 0.0039 | 0.0172 | 0.0128 | 0.0540 | 0.0538 | 0.0890 | 0.0805 | 0.0639 | 0.0589 | 0.0907 | 0.0838 | 0.6801 | 0.7050 | 0.0000 | 0.0005 | 0.0013 | 0.0019 | 0.0030 | 0.0033 | 0.0166 | 0.0196 | 0.0675 | 0.0650 | 0.0968 | 0.1182 | 0.0739 | 0.0715 | 0.0994 | 0.1005 | 0.6416 | 0.6196 | 0.0004 | 0.0015 | 0.0034 | 0.0145 | 0.0574 | 0.1015 | 0.0624 | 0.0915 | 0.6673 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1212 | 580 | | 1103 | 14618 | 561.7 | 138.16 | 35.88 | 63.16 | 370 | 419 | 468 | 517 | 560 | 608 | 658 | 706 | 751 | 0.0501 | 732 | 0.997 | 49.98 | 12.04 | 3 | 0.1024 | 113 | 0.0028 | 12.27 | 6.069 | 0.2960 | 334620.0 | 209000000 | 136000000000 | 91500000000000 | 0.3419 | 0.2943 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.0000 | 0.0170 | 0.0039 | 0.0679 | 0.0309 | 0.1434 | 0.0588 | 0.0830 | 0.0366 | 0.1264 | 0.0723 | 0.5566 | 0.7975 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0049 | 0.0019 | 0.0317 | 0.0272 | 0.0537 | 0.0497 | 0.0305 | 0.0244 | 0.0464 | 0.0384 | 0.8327 | 0.8585 | 0.0035 | 0.0667 | 0.0035 | 0.1000 | 0.0069 | 0.0667 | 0.0277 | 0.0667 | 0.0415 | 0.1667 | 0.1073 | 0.1667 | 0.0415 | 0.1000 | 0.0484 | 0.1333 | 0.7197 | 0.1333 | 0.0000 | 0.0000 | 0.0037 | 0.0147 | 0.0367 | 0.0606 | 0.0495 | 0.0495 | 0.7853 | 5 | 6 | 8 | 9 | 10 | 12 | 16 | 40 | 115 | 0.1429 | 1.10 | 2.444 | 0.5930 | 5276.5 | 1200000 | 317000000 | 92500000000 | 0.4895 | 0.1637 | 0.0684 | 0.0063 | 0.2928 | 0.0125 | 0.3403 | 0.0859 | 0.1521 | 0.2560 | 0.0665 | 0.3196 | 0.0418 | 0.1674 | 0.0209 | 0.0859 | 0.0114 | 0.0358 | 0.0057 | 0.0304 | 0.0003 | 0.0008 | 0.0006 | 0.0013 | 0.0015 | 0.0043 | 0.0150 | 0.0179 | 0.0479 | 0.0415 | 0.0814 | 0.0672 | 0.0568 | 0.0573 | 0.0912 | 0.0851 | 0.7054 | 0.7246 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0043 | 0.0011 | 0.0149 | 0.0164 | 0.0532 | 0.0611 | 0.0987 | 0.1019 | 0.0664 | 0.0710 | 0.1015 | 0.1111 | 0.6610 | 0.6366 | 0.0000 | 0.0003 | 0.0036 | 0.0098 | 0.0577 | 0.0925 | 0.0584 | 0.1013 | 0.6764 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 116 | 222 | | 4981 | 10103 | 405.1 | 89.96 | 157.47 | 168.79 | 303 | 330 | 351 | 372 | 393 | 414 | 437 | 472 | 529 | 0.0726 | 733 | 0.947 | 146.69 | 44.27 | 1 | 0.0765 | 381 | 0.0010 | 46.38 | 7.194 | 0.1694 | 172181.0 | 76900000 | 36100000000 | 17800000000000 | 0.4170 | 0.2320 | 0.0009 | 0.0000 | 0.0006 | 0.0002 | 0.0061 | 0.0002 | 0.0134 | 0.0030 | 0.0510 | 0.0201 | 0.1197 | 0.0402 | 0.1212 | 0.0369 | 0.1555 | 0.0520 | 0.5316 | 0.8474 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0051 | 0.0006 | 0.0261 | 0.0128 | 0.0622 | 0.0261 | 0.0566 | 0.0170 | 0.0832 | 0.0251 | 0.7642 | 0.9184 | 0.0000 | 0.0065 | 0.0095 | 0.0032 | 0.0202 | 0.0356 | 0.0606 | 0.0874 | 0.1021 | 0.1392 | 0.1164 | 0.1359 | 0.1152 | 0.1456 | 0.1318 | 0.1230 | 0.4442 | 0.3236 | 0.0000 | 0.0045 | 0.0050 | 0.0389 | 0.0811 | 0.1241 | 0.0933 | 0.1295 | 0.5236 | 12 | 18 | 27 | 51 | 92 | 149 | 210 | 289 | 400 | 0.0190 | 31.43 | 5.829 | 0.4202 | 53285.1 | 24200000 | 13200000000 | 8210000000000 | 0.4079 | 0.2092 | 0.0230 | 0.0010 | 0.1168 | 0.0114 | 0.2061 | 0.0547 | 0.1914 | 0.1099 | 0.1582 | 0.1932 | 0.1509 | 0.2018 | 0.0846 | 0.1366 | 0.0414 | 0.1376 | 0.0276 | 0.1537 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0011 | 0.0012 | 0.0119 | 0.0086 | 0.0452 | 0.0426 | 0.0796 | 0.0616 | 0.0598 | 0.0476 | 0.0830 | 0.0710 | 0.7189 | 0.7671 | 0.0003 | 0.0007 | 0.0009 | 0.0031 | 0.0060 | 0.0090 | 0.0199 | 0.0193 | 0.0673 | 0.0835 | 0.1185 | 0.1308 | 0.0798 | 0.0860 | 0.1146 | 0.1267 | 0.5929 | 0.5409 | 0.0000 | 0.0010 | 0.0049 | 0.0194 | 0.0537 | 0.0980 | 0.0668 | 0.1011 | 0.6551 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 173 | 580 | | 3314 | 11955 | 517.2 | 91.88 | 119.57 | 243.85 | 373 | 433 | 487 | 512 | 531 | 550 | 573 | 598 | 624 | 0.0613 | 733 | 0.446 | 104.39 | 23.32 | 3 | 0.0993 | 329 | 0.0010 | 41.90 | 7.124 | 0.2030 | 275939.0 | 151000000 | 84400000000 | 48000000000000 | 0.4375 | 0.1965 | 0.0000 | 0.0000 | 0.0029 | 0.0003 | 0.0017 | 0.0003 | 0.0071 | 0.0009 | 0.0384 | 0.0163 | 0.0744 | 0.0359 | 0.0660 | 0.0157 | 0.0994 | 0.0273 | 0.7101 | 0.9033 | 0.0000 | 0.0000 | 0.0011 | 0.0003 | 0.0000 | 0.0003 | 0.0014 | 0.0009 | 0.0206 | 0.0163 | 0.0343 | 0.0359 | 0.0220 | 0.0157 | 0.0354 | 0.0273 | 0.8851 | 0.9033 | 0.0134 | 0.0000 | 0.0160 | 0.0000 | 0.0428 | 0.0000 | 0.0856 | 0.0000 | 0.1096 | 0.0000 | 0.1791 | 0.0000 | 0.1123 | 0.0000 | 0.1417 | 0.0000 | 0.2995 | 0.0000 | 0.0005 | 0.0042 | 0.0094 | 0.0141 | 0.0381 | 0.0522 | 0.0637 | 0.0914 | 0.7262 | 9 | 12 | 14 | 16 | 21 | 31 | 57 | 130 | 371 | 0.1465 | 4.98 | 3.299 | 0.6421 | 73753.8 | 72700000 | 87000000000 | 116000000000000 | 0.4905 | 0.1557 | 0.0398 | 0.0000 | 0.1155 | 0.0121 | 0.1474 | 0.0864 | 0.1932 | 0.1021 | 0.1972 | 0.1690 | 0.1554 | 0.1820 | 0.0777 | 0.1328 | 0.0498 | 0.1235 | 0.0239 | 0.1922 | 0.0000 | 0.0000 | 0.0025 | 0.0012 | 0.0051 | 0.0044 | 0.0108 | 0.0097 | 0.0375 | 0.0400 | 0.0563 | 0.0512 | 0.0512 | 0.0465 | 0.0776 | 0.0787 | 0.7589 | 0.7684 | 0.0000 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0028 | 0.0119 | 0.0127 | 0.0419 | 0.0409 | 0.0608 | 0.0682 | 0.0591 | 0.0564 | 0.0784 | 0.0804 | 0.7466 | 0.7377 | 0.0008 | 0.0008 | 0.0028 | 0.0097 | 0.0399 | 0.0565 | 0.0480 | 0.0871 | 0.7543 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 835 | 674 | | 1286 | 9006 | 107.9 | 35.92 | 236.20 | 179.35 | 71 | 83 | 90 | 96 | 102 | 108 | 115 | 126 | 148 | 0.0815 | 734 | 0.834 | 60.64 | 18.97 | 2 | 0.1260 | 162 | 0.0037 | 21.25 | 5.914 | 0.2852 | 12925.5 | 1750000 | 272000000 | 48100000000 | 0.4873 | 0.1534 | 0.0027 | 0.0000 | 0.0054 | 0.0036 | 0.0308 | 0.0055 | 0.0496 | 0.0173 | 0.1300 | 0.0656 | 0.1662 | 0.0911 | 0.1421 | 0.0647 | 0.1568 | 0.1047 | 0.3164 | 0.6475 | 0.0000 | 0.0000 | 0.0031 | 0.0016 | 0.0134 | 0.0033 | 0.0237 | 0.0124 | 0.0792 | 0.0437 | 0.1132 | 0.0766 | 0.0792 | 0.0445 | 0.1091 | 0.0807 | 0.5792 | 0.7372 | 0.0088 | 0.0086 | 0.0088 | 0.0172 | 0.0265 | 0.0172 | 0.0929 | 0.0862 | 0.1106 | 0.1034 | 0.1593 | 0.1724 | 0.0885 | 0.0690 | 0.1283 | 0.1379 | 0.3761 | 0.3879 | 0.0038 | 0.0095 | 0.0302 | 0.0624 | 0.1078 | 0.1229 | 0.1096 | 0.1153 | 0.4386 | 21 | 54 | 101 | 156 | 212 | 269 | 324 | 398 | 492 | 0.0054 | 44.25 | 6.916 | 0.2857 | 87951.8 | 39600000 | 20100000000 | 11200000000000 | 0.5258 | 0.1424 | 0.0084 | 0.0013 | 0.0560 | 0.0023 | 0.1925 | 0.0179 | 0.2183 | 0.0737 | 0.2022 | 0.1661 | 0.1481 | 0.2268 | 0.0959 | 0.1657 | 0.0541 | 0.1561 | 0.0245 | 0.1900 | 0.0002 | 0.0002 | 0.0010 | 0.0009 | 0.0047 | 0.0025 | 0.0137 | 0.0101 | 0.0490 | 0.0402 | 0.0890 | 0.0809 | 0.0733 | 0.0592 | 0.1002 | 0.0870 | 0.6689 | 0.7190 | 0.0012 | 0.0019 | 0.0030 | 0.0054 | 0.0075 | 0.0103 | 0.0251 | 0.0387 | 0.0681 | 0.0831 | 0.1282 | 0.1543 | 0.1091 | 0.1091 | 0.1372 | 0.1313 | 0.5206 | 0.4659 | 0.0007 | 0.0036 | 0.0053 | 0.0177 | 0.0540 | 0.1087 | 0.0856 | 0.1201 | 0.6042 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 959 | 713 | | 6139 | 10848 | 256.2 | 53.54 | 207.18 | 194.13 | 190 | 210 | 225 | 238 | 252 | 266 | 283 | 302 | 326 | 0.0678 | 736 | 1.177 | 102.18 | 37.66 | 1 | 0.0415 | 255 | 0.0008 | 47.93 | 7.299 | 0.1591 | 68517.0 | 19100000 | 5540000000 | 1670000000000 | 0.4834 | 0.1799 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0032 | 0.0003 | 0.0156 | 0.0014 | 0.0740 | 0.0133 | 0.1454 | 0.0377 | 0.1504 | 0.0343 | 0.1835 | 0.0591 | 0.4267 | 0.8538 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0016 | 0.0002 | 0.0059 | 0.0012 | 0.0355 | 0.0092 | 0.0646 | 0.0250 | 0.0616 | 0.0171 | 0.0826 | 0.0290 | 0.7478 | 0.9183 | 0.0067 | 0.0235 | 0.0114 | 0.0141 | 0.0352 | 0.0469 | 0.0856 | 0.1643 | 0.1369 | 0.1925 | 0.1835 | 0.2207 | 0.1274 | 0.0845 | 0.1340 | 0.0986 | 0.2795 | 0.1549 | 0.0024 | 0.0041 | 0.0093 | 0.0368 | 0.0764 | 0.1195 | 0.1012 | 0.1326 | 0.5176 | 19 | 34 | 61 | 103 | 155 | 210 | 274 | 353 | 472 | 0.0078 | 34.55 | 6.449 | 0.3311 | 80606.7 | 42400000 | 27300000000 | 20400000000000 | 0.4122 | 0.2269 | 0.0375 | 0.0010 | 0.1827 | 0.0076 | 0.2438 | 0.0851 | 0.1774 | 0.1506 | 0.1360 | 0.1962 | 0.1064 | 0.2035 | 0.0572 | 0.1157 | 0.0420 | 0.0994 | 0.0171 | 0.1407 | 0.0008 | 0.0002 | 0.0010 | 0.0012 | 0.0031 | 0.0027 | 0.0179 | 0.0119 | 0.0702 | 0.0586 | 0.1159 | 0.1040 | 0.0844 | 0.0695 | 0.1125 | 0.0949 | 0.5943 | 0.6571 | 0.0016 | 0.0020 | 0.0038 | 0.0020 | 0.0071 | 0.0076 | 0.0245 | 0.0311 | 0.0919 | 0.0967 | 0.1321 | 0.1652 | 0.1025 | 0.1119 | 0.1394 | 0.1317 | 0.4971 | 0.4518 | 0.0016 | 0.0016 | 0.0043 | 0.0200 | 0.0832 | 0.1402 | 0.0836 | 0.1216 | 0.5440 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1030 | 654 | | 4733 | 10425 | 467.9 | 107.24 | 95.77 | 122.81 | 345 | 379 | 404 | 428 | 451 | 479 | 509 | 550 | 613 | 0.0706 | 736 | 0.617 | 150.66 | 41.15 | 1 | 0.0909 | 430 | 0.0008 | 55.01 | 7.358 | 0.1623 | 230448.0 | 120000000 | 65300000000 | 37500000000000 | 0.3787 | 0.2634 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0007 | 0.0134 | 0.0009 | 0.0647 | 0.0210 | 0.1390 | 0.0495 | 0.1451 | 0.0401 | 0.1678 | 0.0472 | 0.4677 | 0.8406 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0006 | 0.0057 | 0.0004 | 0.0302 | 0.0145 | 0.0629 | 0.0288 | 0.0577 | 0.0177 | 0.0847 | 0.0228 | 0.7570 | 0.9150 | 0.0023 | 0.0000 | 0.0070 | 0.0000 | 0.0151 | 0.0201 | 0.0568 | 0.0936 | 0.1230 | 0.1472 | 0.1647 | 0.2107 | 0.0974 | 0.1037 | 0.1334 | 0.1171 | 0.4002 | 0.3077 | 0.0005 | 0.0024 | 0.0063 | 0.0250 | 0.0794 | 0.1414 | 0.1034 | 0.1255 | 0.5161 | 8 | 10 | 12 | 16 | 31 | 66 | 119 | 187 | 269 | 0.0567 | 15.85 | 4.921 | 0.5294 | 24254.7 | 8620000 | 3790000000 | 1970000000000 | 0.5285 | 0.1189 | 0.0542 | 0.0020 | 0.2045 | 0.0127 | 0.3074 | 0.1029 | 0.1864 | 0.1470 | 0.1140 | 0.2238 | 0.0695 | 0.2285 | 0.0320 | 0.1142 | 0.0209 | 0.0788 | 0.0111 | 0.0902 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0003 | 0.0011 | 0.0095 | 0.0066 | 0.0504 | 0.0403 | 0.0831 | 0.0816 | 0.0652 | 0.0504 | 0.0967 | 0.0809 | 0.6944 | 0.7391 | 0.0000 | 0.0000 | 0.0013 | 0.0003 | 0.0019 | 0.0021 | 0.0107 | 0.0164 | 0.0630 | 0.0649 | 0.1047 | 0.1238 | 0.0740 | 0.0795 | 0.1160 | 0.1196 | 0.6286 | 0.5934 | 0.0000 | 0.0003 | 0.0014 | 0.0107 | 0.0546 | 0.0976 | 0.0658 | 0.1029 | 0.6668 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 792 | 805 | | 4919 | 8206 | 382.1 | 68.91 | 141.31 | 188.12 | 300 | 324 | 344 | 360 | 375 | 392 | 412 | 438 | 476 | 0.0898 | 737 | 1.029 | 141.51 | 47.89 | 1 | 0.0732 | 360 | 0.0011 | 37.46 | 7.089 | 0.1984 | 150764.0 | 61400000 | 25800000000 | 11200000000000 | 0.4301 | 0.2151 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0030 | 0.0000 | 0.0107 | 0.0015 | 0.0411 | 0.0153 | 0.0748 | 0.0283 | 0.0789 | 0.0233 | 0.1114 | 0.0344 | 0.6794 | 0.8971 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0041 | 0.0008 | 0.0202 | 0.0133 | 0.0357 | 0.0198 | 0.0359 | 0.0131 | 0.0538 | 0.0182 | 0.8484 | 0.9348 | 0.0014 | 0.0000 | 0.0043 | 0.0000 | 0.0216 | 0.0000 | 0.0620 | 0.0000 | 0.1037 | 0.0000 | 0.1527 | 0.0000 | 0.1081 | 0.0000 | 0.1326 | 0.0000 | 0.4135 | 0.0000 | 0.0022 | 0.0022 | 0.0118 | 0.0263 | 0.0679 | 0.1121 | 0.0937 | 0.1222 | 0.5617 | 17 | 22 | 29 | 36 | 53 | 94 | 149 | 244 | 370 | 0.0319 | 21.94 | 5.086 | 0.5347 | 55351.4 | 34100000 | 26500000000 | 23500000000000 | 0.4596 | 0.1622 | 0.0237 | 0.0014 | 0.1379 | 0.0121 | 0.2020 | 0.0752 | 0.1323 | 0.1079 | 0.1295 | 0.1526 | 0.1337 | 0.1923 | 0.0975 | 0.1214 | 0.0641 | 0.1008 | 0.0794 | 0.2363 | 0.0000 | 0.0000 | 0.0010 | 0.0003 | 0.0007 | 0.0012 | 0.0104 | 0.0064 | 0.0542 | 0.0436 | 0.0808 | 0.0753 | 0.0636 | 0.0516 | 0.0855 | 0.0680 | 0.7037 | 0.7537 | 0.0013 | 0.0000 | 0.0000 | 0.0010 | 0.0018 | 0.0015 | 0.0075 | 0.0185 | 0.0755 | 0.0713 | 0.1132 | 0.1307 | 0.0644 | 0.0723 | 0.1012 | 0.1142 | 0.6350 | 0.5905 | 0.0004 | 0.0008 | 0.0016 | 0.0117 | 0.0600 | 0.1028 | 0.0631 | 0.0919 | 0.6678 |