High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 680 | 628 | | 3358 | 11383 | 103.9 | 36.00 | 189.92 | 222.69 | 55 | 73 | 87 | 96 | 104 | 113 | 121 | 132 | 150 | 0.0693 | 789 | 0.744 | 53.00 | 13.15 | 2 | 0.0408 | 137 | 0.0010 | 53.73 | 7.119 | 0.1747 | 12086.9 | 1530000 | 208000000 | 30200000000 | 0.4241 | 0.1918 | 0.0000 | 0.0000 | 0.0045 | 0.0012 | 0.0166 | 0.0028 | 0.0487 | 0.0107 | 0.1236 | 0.0396 | 0.1818 | 0.0832 | 0.1639 | 0.0788 | 0.1748 | 0.1097 | 0.2862 | 0.6739 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0065 | 0.0034 | 0.0352 | 0.0250 | 0.0660 | 0.0370 | 0.0567 | 0.0301 | 0.0895 | 0.0510 | 0.7456 | 0.8534 | 0.0011 | 0.0025 | 0.0066 | 0.0127 | 0.0287 | 0.0253 | 0.0562 | 0.0911 | 0.1257 | 0.1671 | 0.1312 | 0.1873 | 0.1125 | 0.1013 | 0.1389 | 0.1646 | 0.3991 | 0.2481 | 0.0023 | 0.0006 | 0.0053 | 0.0299 | 0.0679 | 0.1066 | 0.0978 | 0.1101 | 0.5796 | 14 | 17 | 23 | 40 | 82 | 156 | 248 | 368 | 533 | 0.0760 | 19.94 | 5.078 | 0.5051 | 85655.4 | 51000000 | 35300000000 | 27300000000000 | 0.6172 | 0.0984 | 0.0318 | 0.0041 | 0.1500 | 0.0191 | 0.2403 | 0.0909 | 0.1748 | 0.1415 | 0.1639 | 0.1829 | 0.1281 | 0.1921 | 0.0616 | 0.1271 | 0.0318 | 0.1054 | 0.0179 | 0.1369 | 0.0002 | 0.0006 | 0.0011 | 0.0010 | 0.0067 | 0.0019 | 0.0132 | 0.0101 | 0.0529 | 0.0477 | 0.1008 | 0.0924 | 0.0697 | 0.0570 | 0.0934 | 0.0891 | 0.6621 | 0.7003 | 0.0014 | 0.0009 | 0.0047 | 0.0046 | 0.0143 | 0.0118 | 0.0201 | 0.0236 | 0.0593 | 0.0611 | 0.1023 | 0.1045 | 0.0662 | 0.0856 | 0.1017 | 0.1135 | 0.6300 | 0.5945 | 0.0005 | 0.0017 | 0.0083 | 0.0225 | 0.0605 | 0.1037 | 0.0722 | 0.0930 | 0.6376 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 146 | 887 | | 7631 | 21436 | 727.6 | 138.83 | 177.21 | 164.76 | 559 | 609 | 647 | 680 | 711 | 747 | 788 | 842 | 928 | 0.0466 | 999 | 1.151 | 109.39 | 39.66 | 3 | 0.0358 | 273 | 0.0005 | 96.74 | 7.799 | 0.1272 | 548709.0 | 428000000 | 346000000000 | 288000000000000 | 0.4347 | 0.2091 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0098 | 0.0011 | 0.0577 | 0.0148 | 0.1275 | 0.0300 | 0.1226 | 0.0286 | 0.1538 | 0.0479 | 0.5265 | 0.8776 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0040 | 0.0001 | 0.0261 | 0.0111 | 0.0570 | 0.0203 | 0.0558 | 0.0116 | 0.0815 | 0.0188 | 0.7746 | 0.9381 | 0.0024 | 0.0271 | 0.0065 | 0.0226 | 0.0212 | 0.1041 | 0.0637 | 0.1719 | 0.1371 | 0.1900 | 0.1853 | 0.1900 | 0.1273 | 0.1538 | 0.1510 | 0.0860 | 0.3053 | 0.0543 | 0.0020 | 0.0038 | 0.0116 | 0.0358 | 0.0832 | 0.1282 | 0.1170 | 0.1331 | 0.4854 | 19 | 36 | 62 | 97 | 135 | 178 | 225 | 286 | 389 | 0.0094 | 25.15 | 6.072 | 0.3627 | 58546.5 | 27800000 | 17200000000 | 13100000000000 | 0.4795 | 0.1685 | 0.0412 | 0.0013 | 0.1579 | 0.0105 | 0.2563 | 0.0772 | 0.1701 | 0.1359 | 0.1559 | 0.1808 | 0.1097 | 0.2006 | 0.0682 | 0.1460 | 0.0319 | 0.1267 | 0.0087 | 0.1208 | 0.0003 | 0.0003 | 0.0011 | 0.0011 | 0.0045 | 0.0011 | 0.0186 | 0.0128 | 0.0660 | 0.0509 | 0.1297 | 0.1018 | 0.1036 | 0.0883 | 0.1381 | 0.1190 | 0.5381 | 0.6246 | 0.0013 | 0.0031 | 0.0053 | 0.0081 | 0.0151 | 0.0171 | 0.0419 | 0.0463 | 0.0956 | 0.1170 | 0.1640 | 0.1725 | 0.1258 | 0.1325 | 0.1545 | 0.1478 | 0.3965 | 0.3555 | 0.0009 | 0.0027 | 0.0070 | 0.0268 | 0.0857 | 0.1465 | 0.1242 | 0.1468 | 0.4593 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 592 | 447 | | 14268 | 31171 | 276.5 | 63.92 | 156.47 | 200.54 | 198 | 221 | 239 | 256 | 272 | 288 | 306 | 329 | 363 | 0.0479 | 1493 | 1.112 | 122.50 | 42.44 | 2 | 0.0226 | 322 | 0.0005 | 82.25 | 7.811 | 0.1476 | 80557.2 | 24600000 | 7880000000 | 2630000000000 | 0.4955 | 0.1599 | 0.0002 | 0.0001 | 0.0005 | 0.0001 | 0.0060 | 0.0004 | 0.0222 | 0.0013 | 0.0747 | 0.0210 | 0.1425 | 0.0397 | 0.1357 | 0.0415 | 0.1626 | 0.0645 | 0.4556 | 0.8315 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0051 | 0.0007 | 0.0308 | 0.0126 | 0.0628 | 0.0213 | 0.0597 | 0.0187 | 0.0832 | 0.0292 | 0.7574 | 0.9174 | 0.0026 | 0.0113 | 0.0079 | 0.0213 | 0.0229 | 0.0464 | 0.0649 | 0.1004 | 0.1302 | 0.1757 | 0.1868 | 0.2045 | 0.1028 | 0.1142 | 0.1388 | 0.1380 | 0.3432 | 0.1882 | 0.0004 | 0.0016 | 0.0070 | 0.0240 | 0.0851 | 0.1323 | 0.0987 | 0.1321 | 0.5187 | 11 | 14 | 18 | 26 | 57 | 113 | 187 | 292 | 453 | 0.0385 | 36.22 | 5.629 | 0.4704 | 64696.1 | 37000000 | 25200000000 | 19300000000000 | 0.4742 | 0.1836 | 0.0255 | 0.0014 | 0.1594 | 0.0110 | 0.2636 | 0.0618 | 0.1760 | 0.1240 | 0.1590 | 0.2011 | 0.1042 | 0.2139 | 0.0552 | 0.1298 | 0.0320 | 0.1236 | 0.0251 | 0.1333 | 0.0001 | 0.0001 | 0.0011 | 0.0007 | 0.0017 | 0.0016 | 0.0083 | 0.0060 | 0.0509 | 0.0418 | 0.0820 | 0.0672 | 0.0623 | 0.0538 | 0.0920 | 0.0797 | 0.7017 | 0.7491 | 0.0003 | 0.0008 | 0.0022 | 0.0016 | 0.0045 | 0.0054 | 0.0174 | 0.0185 | 0.0624 | 0.0667 | 0.0988 | 0.1125 | 0.0795 | 0.0787 | 0.1028 | 0.1074 | 0.6320 | 0.6083 | 0.0001 | 0.0006 | 0.0031 | 0.0120 | 0.0572 | 0.0936 | 0.0702 | 0.0963 | 0.6669 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 328 | 685 | | 3310 | 17319 | 115.5 | 44.52 | 5.43 | 1.99 | 62 | 70 | 80 | 93 | 109 | 124 | 140 | 161 | 181 | 0.0577 | 999 | 0.991 | 31.40 | 10.77 | 2 | 0.0266 | 88 | 0.0050 | 4.21 | 5.619 | 0.4414 | 15310.3 | 2260000 | 362000000 | 61100000000 | 0.3498 | 0.2779 | 0.0021 | 0.0010 | 0.0072 | 0.0039 | 0.0123 | 0.0093 | 0.0349 | 0.0181 | 0.0739 | 0.0366 | 0.1242 | 0.0439 | 0.1232 | 0.0649 | 0.1828 | 0.0825 | 0.4394 | 0.7399 | 0.0005 | 0.0007 | 0.0015 | 0.0026 | 0.0035 | 0.0048 | 0.0089 | 0.0096 | 0.0212 | 0.0177 | 0.0227 | 0.0184 | 0.0257 | 0.0302 | 0.0420 | 0.0350 | 0.8741 | 0.8809 | 0.0010 | 0.0000 | 0.0019 | 0.0045 | 0.0086 | 0.0106 | 0.0209 | 0.0151 | 0.0409 | 0.0452 | 0.0571 | 0.0603 | 0.0523 | 0.0724 | 0.0647 | 0.0799 | 0.7526 | 0.7119 | 0.0013 | 0.0000 | 0.0013 | 0.0097 | 0.0232 | 0.0387 | 0.0290 | 0.0574 | 0.8395 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.2714 | 0.47 | 1.049 | 0.6358 | 33.5 | 227.156 | 1669.44 | 13153.9 | 0.4485 | 0.2089 | 0.0313 | 0.0023 | 0.0940 | 0.0125 | 0.1602 | 0.0406 | 0.2077 | 0.0829 | 0.2080 | 0.1416 | 0.1737 | 0.2164 | 0.0888 | 0.2463 | 0.0321 | 0.1826 | 0.0043 | 0.0747 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0030 | 0.0008 | 0.0099 | 0.0050 | 0.0301 | 0.0153 | 0.0780 | 0.0258 | 0.2017 | 0.0630 | 0.3485 | 0.2345 | 0.3287 | 0.6554 | 0.0177 | 0.0768 | 0.0775 | 0.1643 | 0.1302 | 0.2136 | 0.1742 | 0.2130 | 0.1942 | 0.1573 | 0.1860 | 0.0951 | 0.1327 | 0.0548 | 0.0683 | 0.0195 | 0.0192 | 0.0057 | 0.0007 | 0.0109 | 0.0459 | 0.1123 | 0.1876 | 0.2387 | 0.2118 | 0.1393 | 0.0528 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 969 | 728 | | 16378 | 49009 | 195.5 | 37.68 | 203.96 | 331.62 | 151 | 169 | 180 | 189 | 198 | 206 | 215 | 226 | 241 | 0.0278 | 1362 | 1.188 | 93.09 | 34.48 | 1 | 0.0143 | 235 | 0.0032 | 12.80 | 6.161 | 0.3225 | 39638.5 | 8270000 | 1770000000 | 387000000000 | 0.4222 | 0.2262 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0037 | 0.0000 | 0.0129 | 0.0003 | 0.0346 | 0.0080 | 0.0661 | 0.0181 | 0.0824 | 0.0160 | 0.1152 | 0.0268 | 0.6836 | 0.9309 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0036 | 0.0001 | 0.0120 | 0.0068 | 0.0260 | 0.0139 | 0.0283 | 0.0069 | 0.0418 | 0.0107 | 0.8870 | 0.9616 | 0.0089 | 0.0576 | 0.0166 | 0.0995 | 0.0426 | 0.1047 | 0.0736 | 0.1780 | 0.1192 | 0.1937 | 0.1473 | 0.1675 | 0.1256 | 0.0733 | 0.1456 | 0.0890 | 0.3206 | 0.0366 | 0.0012 | 0.0027 | 0.0072 | 0.0202 | 0.0501 | 0.0834 | 0.0821 | 0.1197 | 0.6333 | 7 | 8 | 10 | 12 | 17 | 54 | 192 | 390 | 701 | 0.1432 | 35.53 | 4.788 | 0.5519 | 151568.0 | 149000000 | 169000000000 | 211000000000000 | 0.4292 | 0.2197 | 0.0529 | 0.0035 | 0.2034 | 0.0131 | 0.2775 | 0.1127 | 0.1544 | 0.1604 | 0.1262 | 0.2014 | 0.0909 | 0.1979 | 0.0516 | 0.1081 | 0.0322 | 0.1003 | 0.0110 | 0.1027 | 0.0001 | 0.0001 | 0.0003 | 0.0001 | 0.0010 | 0.0003 | 0.0081 | 0.0057 | 0.0395 | 0.0371 | 0.0691 | 0.0641 | 0.0487 | 0.0414 | 0.0700 | 0.0648 | 0.7633 | 0.7864 | 0.0004 | 0.0003 | 0.0011 | 0.0011 | 0.0028 | 0.0036 | 0.0129 | 0.0138 | 0.0452 | 0.0466 | 0.0753 | 0.0825 | 0.0565 | 0.0561 | 0.0729 | 0.0789 | 0.7329 | 0.7170 | 0.0001 | 0.0013 | 0.0022 | 0.0102 | 0.0423 | 0.0730 | 0.0512 | 0.0723 | 0.7473 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 724 | | 2796 | 6922 | 1289.3 | 297.81 | 11.57 | 14.75 | 882 | 996 | 1126 | 1218 | 1314 | 1409 | 1473 | 1547 | 1666 | 0.1000 | 692 | 0.449 | 77.06 | 17.03 | 1 | 0.0898 | 251 | 0.0006 | 162.50 | 7.490 | 0.1405 | 1750000.0 | 2480000000 | 3640000000000 | 5.5E+15 | 0.4200 | 0.2151 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0006 | 0.0000 | 0.0150 | 0.0008 | 0.0807 | 0.0218 | 0.1502 | 0.0514 | 0.1120 | 0.0327 | 0.1352 | 0.0510 | 0.5063 | 0.8419 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0004 | 0.0334 | 0.0184 | 0.0621 | 0.0376 | 0.0375 | 0.0192 | 0.0570 | 0.0289 | 0.8086 | 0.8955 | 0.0036 | 0.0000 | 0.0125 | 0.0215 | 0.0179 | 0.0538 | 0.0339 | 0.1075 | 0.1179 | 0.1720 | 0.1732 | 0.2151 | 0.0875 | 0.1183 | 0.1304 | 0.1720 | 0.4232 | 0.1398 | 0.0000 | 0.0000 | 0.0007 | 0.0061 | 0.0509 | 0.1141 | 0.0645 | 0.0971 | 0.6667 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 16 | 0.1442 | 0.50 | 1.438 | 0.5109 | 351.5 | 25544.2 | 2750000 | 377000000 | 0.5711 | 0.1027 | 0.1170 | 0.0291 | 0.1623 | 0.0624 | 0.1857 | 0.0979 | 0.1798 | 0.1155 | 0.1535 | 0.1440 | 0.0892 | 0.1715 | 0.0738 | 0.1552 | 0.0322 | 0.1366 | 0.0066 | 0.0877 | 0.0708 | 0.0240 | 0.0893 | 0.0506 | 0.0777 | 0.0776 | 0.0796 | 0.0886 | 0.0949 | 0.1002 | 0.0888 | 0.1140 | 0.1000 | 0.1166 | 0.1124 | 0.1369 | 0.2864 | 0.2915 | 0.0290 | 0.0090 | 0.0139 | 0.0030 | 0.0189 | 0.0060 | 0.0391 | 0.0571 | 0.1009 | 0.1141 | 0.1072 | 0.1096 | 0.0971 | 0.1096 | 0.1299 | 0.1276 | 0.4641 | 0.4640 | 0.0730 | 0.0589 | 0.0518 | 0.0754 | 0.0761 | 0.0934 | 0.1013 | 0.0879 | 0.3823 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1270 | 935 | | 2332 | 2784 | 77.0 | 17.41 | 147.31 | 171.19 | 57 | 63 | 67 | 71 | 75 | 79 | 84 | 90 | 98 | 0.1566 | 436 | 0.850 | 77.94 | 29.70 | 1 | 0.1038 | 242 | 0.0063 | 9.67 | 5.383 | 0.3501 | 6226.1 | 531430 | 48100000 | 4640000000 | 0.4627 | 0.1874 | 0.0013 | 0.0000 | 0.0038 | 0.0005 | 0.0089 | 0.0014 | 0.0335 | 0.0046 | 0.0772 | 0.0246 | 0.1392 | 0.0483 | 0.1512 | 0.0433 | 0.1980 | 0.0724 | 0.3871 | 0.8050 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0031 | 0.0000 | 0.0098 | 0.0013 | 0.0411 | 0.0183 | 0.0878 | 0.0404 | 0.0734 | 0.0243 | 0.1145 | 0.0469 | 0.6689 | 0.8688 | 0.0109 | 0.0189 | 0.0327 | 0.0189 | 0.0463 | 0.0566 | 0.1308 | 0.1509 | 0.1417 | 0.1887 | 0.1989 | 0.2264 | 0.1144 | 0.0943 | 0.1608 | 0.1321 | 0.1635 | 0.1132 | 0.0028 | 0.0123 | 0.0274 | 0.0482 | 0.1154 | 0.1703 | 0.1060 | 0.1552 | 0.3623 | 13 | 16 | 21 | 34 | 74 | 129 | 190 | 273 | 377 | 0.0284 | 57.62 | 5.532 | 0.4008 | 50997.4 | 24600000 | 14500000000 | 9660000000000 | 0.5052 | 0.1542 | 0.0789 | 0.0074 | 0.2366 | 0.0391 | 0.2258 | 0.1657 | 0.1075 | 0.1304 | 0.1004 | 0.1657 | 0.1183 | 0.1657 | 0.0824 | 0.1229 | 0.0323 | 0.0838 | 0.0179 | 0.1192 | 0.0017 | 0.0000 | 0.0017 | 0.0008 | 0.0051 | 0.0084 | 0.0146 | 0.0114 | 0.0788 | 0.0729 | 0.1311 | 0.1109 | 0.0874 | 0.0858 | 0.1482 | 0.1291 | 0.5313 | 0.5809 | 0.0011 | 0.0000 | 0.0045 | 0.0064 | 0.0124 | 0.0141 | 0.0236 | 0.0295 | 0.1025 | 0.1013 | 0.1577 | 0.1782 | 0.1092 | 0.1115 | 0.1441 | 0.1449 | 0.4448 | 0.4141 | 0.0020 | 0.0039 | 0.0039 | 0.0225 | 0.1000 | 0.1324 | 0.1049 | 0.1471 | 0.4833 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 835 | 668 | | 9436 | 26949 | 509.0 | 119.52 | 167.87 | 203.60 | 373 | 412 | 441 | 467 | 495 | 522 | 555 | 598 | 668 | 0.0413 | 1112 | 0.662 | 166.43 | 45.61 | 1 | 0.0520 | 491 | 0.0006 | 62.28 | 7.676 | 0.1552 | 273329.0 | 155000000 | 92900000000 | 58900000000000 | 0.4414 | 0.2158 | 0.0005 | 0.0000 | 0.0010 | 0.0001 | 0.0045 | 0.0001 | 0.0160 | 0.0016 | 0.0599 | 0.0173 | 0.1253 | 0.0382 | 0.1333 | 0.0410 | 0.1696 | 0.0533 | 0.4898 | 0.8484 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0056 | 0.0004 | 0.0284 | 0.0114 | 0.0665 | 0.0214 | 0.0584 | 0.0205 | 0.0867 | 0.0273 | 0.7535 | 0.9190 | 0.0030 | 0.0000 | 0.0095 | 0.0141 | 0.0233 | 0.0194 | 0.0531 | 0.0952 | 0.1103 | 0.1411 | 0.1455 | 0.1711 | 0.0960 | 0.0935 | 0.1306 | 0.1323 | 0.4287 | 0.3333 | 0.0002 | 0.0045 | 0.0079 | 0.0271 | 0.0857 | 0.1202 | 0.0911 | 0.1114 | 0.5519 | 8 | 11 | 17 | 36 | 77 | 141 | 218 | 316 | 466 | 0.0551 | 40.07 | 5.701 | 0.4557 | 69631.7 | 39300000 | 26800000000 | 21000000000000 | 0.4485 | 0.1832 | 0.0434 | 0.0008 | 0.1902 | 0.0126 | 0.2802 | 0.1166 | 0.1517 | 0.1613 | 0.1292 | 0.2019 | 0.0888 | 0.1955 | 0.0589 | 0.1175 | 0.0323 | 0.0958 | 0.0254 | 0.0979 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0093 | 0.0067 | 0.0549 | 0.0483 | 0.1006 | 0.0833 | 0.0610 | 0.0527 | 0.0967 | 0.0874 | 0.6773 | 0.7214 | 0.0002 | 0.0004 | 0.0009 | 0.0003 | 0.0012 | 0.0017 | 0.0175 | 0.0227 | 0.0800 | 0.0909 | 0.1203 | 0.1382 | 0.0793 | 0.0819 | 0.1150 | 0.1299 | 0.5857 | 0.5341 | 0.0000 | 0.0002 | 0.0021 | 0.0123 | 0.0723 | 0.1039 | 0.0750 | 0.1098 | 0.6245 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1074 | 469 | | 856 | 4211 | 285.4 | 67.25 | 6.42 | 2.65 | 204 | 219 | 238 | 258 | 279 | 298 | 314 | 342 | 392 | 0.0912 | 384 | 0.307 | 78.41 | 12.65 | 1 | 0.3540 | 303 | 0.0100 | 2.29 | 4.835 | 0.5114 | 85984.1 | 27300000 | 9080000000 | 3150000000000 | 0.3537 | 0.2878 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0190 | 0.0026 | 0.0634 | 0.0408 | 0.1142 | 0.0829 | 0.0846 | 0.0421 | 0.1078 | 0.0523 | 0.6110 | 0.7793 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0078 | 0.0012 | 0.0310 | 0.0315 | 0.0620 | 0.0619 | 0.0326 | 0.0245 | 0.0419 | 0.0304 | 0.8248 | 0.8505 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0139 | 0.0407 | 0.0139 | 0.0407 | 0.1389 | 0.0872 | 0.1389 | 0.0814 | 0.0694 | 0.0930 | 0.1250 | 0.6453 | 0.5000 | 0.0000 | 0.0000 | 0.0025 | 0.0100 | 0.0549 | 0.0549 | 0.0499 | 0.0998 | 0.7282 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 10 | 0.0710 | 0.33 | 0.864 | 0.2971 | 48.3 | 412.798 | 3958 | 42046.3 | 0.4542 | 0.1770 | 0.0146 | 0.0016 | 0.0652 | 0.0082 | 0.1429 | 0.0216 | 0.2233 | 0.0554 | 0.2280 | 0.0976 | 0.2045 | 0.1628 | 0.0871 | 0.2473 | 0.0323 | 0.2561 | 0.0021 | 0.1494 | 0.0003 | 0.0000 | 0.0085 | 0.0008 | 0.0241 | 0.0043 | 0.0564 | 0.0112 | 0.1146 | 0.0394 | 0.1580 | 0.0765 | 0.1970 | 0.1501 | 0.1932 | 0.2793 | 0.2479 | 0.4384 | 0.0927 | 0.1488 | 0.1418 | 0.1187 | 0.1354 | 0.1116 | 0.1297 | 0.1259 | 0.1088 | 0.1731 | 0.1128 | 0.1173 | 0.1225 | 0.0959 | 0.0798 | 0.0658 | 0.0766 | 0.0429 | 0.0125 | 0.0467 | 0.0780 | 0.1010 | 0.1263 | 0.1364 | 0.1335 | 0.1557 | 0.2100 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 610 | 740 | | 10995 | 21735 | 347.4 | 98.02 | 165.63 | 275.68 | 237 | 265 | 287 | 309 | 330 | 354 | 385 | 424 | 482 | 0.0543 | 1180 | 0.823 | 156.77 | 42.94 | 1 | 0.0379 | 417 | 0.0006 | 76.46 | 7.762 | 0.1421 | 130306.0 | 52800000 | 23000000000 | 10800000000000 | 0.4099 | 0.2391 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0050 | 0.0004 | 0.0293 | 0.0030 | 0.0976 | 0.0224 | 0.1934 | 0.0609 | 0.1532 | 0.0578 | 0.1697 | 0.0815 | 0.3511 | 0.7739 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0001 | 0.0100 | 0.0014 | 0.0366 | 0.0128 | 0.0819 | 0.0266 | 0.0642 | 0.0246 | 0.0880 | 0.0371 | 0.7185 | 0.8974 | 0.0021 | 0.0038 | 0.0037 | 0.0104 | 0.0099 | 0.0133 | 0.0489 | 0.0579 | 0.1039 | 0.1670 | 0.1691 | 0.2201 | 0.1158 | 0.0911 | 0.1404 | 0.1670 | 0.4064 | 0.2695 | 0.0002 | 0.0032 | 0.0077 | 0.0270 | 0.0753 | 0.1302 | 0.0823 | 0.1115 | 0.5626 | 7 | 9 | 11 | 13 | 23 | 59 | 139 | 282 | 558 | 0.1212 | 27.49 | 4.518 | 0.5579 | 103430.0 | 90600000 | 93300000000 | 107000000000000 | 0.5655 | 0.1379 | 0.0639 | 0.0036 | 0.1916 | 0.0216 | 0.2652 | 0.1161 | 0.1568 | 0.1490 | 0.1285 | 0.1970 | 0.0930 | 0.1954 | 0.0558 | 0.1189 | 0.0323 | 0.1029 | 0.0129 | 0.0953 | 0.0002 | 0.0003 | 0.0003 | 0.0003 | 0.0008 | 0.0007 | 0.0092 | 0.0067 | 0.0505 | 0.0462 | 0.0921 | 0.0768 | 0.0586 | 0.0549 | 0.0894 | 0.0845 | 0.6990 | 0.7296 | 0.0004 | 0.0002 | 0.0007 | 0.0000 | 0.0020 | 0.0010 | 0.0127 | 0.0148 | 0.0665 | 0.0758 | 0.1061 | 0.1131 | 0.0700 | 0.0705 | 0.1023 | 0.1056 | 0.6393 | 0.6190 | 0.0003 | 0.0007 | 0.0012 | 0.0100 | 0.0608 | 0.1027 | 0.0621 | 0.0993 | 0.6629 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 395 | 643 | | 5110 | 12647 | 411.8 | 82.88 | 98.24 | 223.44 | 296 | 332 | 362 | 387 | 413 | 442 | 469 | 492 | 516 | 0.0659 | 833 | 1.130 | 86.12 | 29.43 | 1 | 0.0421 | 215 | 0.0017 | 11.85 | 6.634 | 0.3156 | 176415.0 | 78200000 | 35700000000 | 16700000000000 | 0.4107 | 0.2254 | 0.0009 | 0.0000 | 0.0028 | 0.0000 | 0.0066 | 0.0000 | 0.0133 | 0.0006 | 0.0344 | 0.0142 | 0.0667 | 0.0259 | 0.0689 | 0.0150 | 0.0910 | 0.0273 | 0.7153 | 0.9170 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0027 | 0.0000 | 0.0046 | 0.0006 | 0.0126 | 0.0131 | 0.0239 | 0.0224 | 0.0220 | 0.0115 | 0.0305 | 0.0206 | 0.9023 | 0.9318 | 0.0041 | 0.0000 | 0.0072 | 0.1290 | 0.0103 | 0.1935 | 0.0351 | 0.1290 | 0.0784 | 0.2258 | 0.0991 | 0.2258 | 0.0877 | 0.0645 | 0.1290 | 0.0323 | 0.5490 | 0.0000 | 0.0004 | 0.0043 | 0.0031 | 0.0105 | 0.0233 | 0.0361 | 0.0415 | 0.0562 | 0.8247 | 7 | 8 | 10 | 11 | 13 | 16 | 30 | 87 | 318 | 0.2398 | 18.28 | 3.252 | 0.6811 | 59570.0 | 56500000 | 65600000000 | 86800000000000 | 0.3448 | 0.2408 | 0.0274 | 0.0023 | 0.1471 | 0.0150 | 0.2893 | 0.0495 | 0.1845 | 0.1164 | 0.1621 | 0.2085 | 0.0998 | 0.2385 | 0.0299 | 0.1336 | 0.0324 | 0.1083 | 0.0274 | 0.1279 | 0.0000 | 0.0007 | 0.0004 | 0.0007 | 0.0015 | 0.0020 | 0.0091 | 0.0078 | 0.0380 | 0.0346 | 0.0673 | 0.0620 | 0.0395 | 0.0400 | 0.0589 | 0.0491 | 0.7852 | 0.8032 | 0.0009 | 0.0005 | 0.0040 | 0.0010 | 0.0040 | 0.0024 | 0.0094 | 0.0086 | 0.0395 | 0.0427 | 0.0686 | 0.0734 | 0.0413 | 0.0504 | 0.0659 | 0.0705 | 0.7663 | 0.7505 | 0.0004 | 0.0013 | 0.0042 | 0.0129 | 0.0400 | 0.0642 | 0.0396 | 0.0554 | 0.7821 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 382 | 242 | | 12664 | 34586 | 373.4 | 98.30 | 213.98 | 284.63 | 263 | 291 | 313 | 335 | 358 | 382 | 408 | 446 | 511 | 0.0376 | 1299 | 0.766 | 102.08 | 31.62 | 1 | 0.0237 | 300 | 0.0005 | 74.63 | 7.800 | 0.1485 | 149085.0 | 63700000 | 29200000000 | 14200000000000 | 0.4340 | 0.2186 | 0.0003 | 0.0001 | 0.0035 | 0.0000 | 0.0057 | 0.0011 | 0.0212 | 0.0027 | 0.0752 | 0.0188 | 0.1495 | 0.0375 | 0.1557 | 0.0407 | 0.1833 | 0.0594 | 0.4057 | 0.8397 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0016 | 0.0000 | 0.0071 | 0.0004 | 0.0383 | 0.0102 | 0.0764 | 0.0200 | 0.0727 | 0.0183 | 0.1055 | 0.0299 | 0.6974 | 0.9212 | 0.0052 | 0.0055 | 0.0048 | 0.0036 | 0.0180 | 0.0155 | 0.0557 | 0.0675 | 0.0894 | 0.1150 | 0.1198 | 0.1359 | 0.0802 | 0.1004 | 0.1066 | 0.1305 | 0.5202 | 0.4261 | 0.0011 | 0.0038 | 0.0108 | 0.0345 | 0.0819 | 0.1264 | 0.0936 | 0.1140 | 0.5339 | 10 | 14 | 21 | 42 | 78 | 144 | 249 | 393 | 629 | 0.0536 | 36.30 | 5.670 | 0.4778 | 126798.0 | 105000000 | 105000000000 | 118000000000000 | 0.3874 | 0.2464 | 0.0531 | 0.0011 | 0.1879 | 0.0093 | 0.2767 | 0.0927 | 0.1677 | 0.1537 | 0.1237 | 0.2297 | 0.0869 | 0.1936 | 0.0497 | 0.1194 | 0.0326 | 0.0973 | 0.0216 | 0.1031 | 0.0002 | 0.0002 | 0.0003 | 0.0005 | 0.0015 | 0.0010 | 0.0112 | 0.0071 | 0.0544 | 0.0452 | 0.0794 | 0.0732 | 0.0619 | 0.0524 | 0.0887 | 0.0799 | 0.7024 | 0.7405 | 0.0007 | 0.0001 | 0.0007 | 0.0009 | 0.0015 | 0.0024 | 0.0132 | 0.0185 | 0.0721 | 0.0749 | 0.1034 | 0.1143 | 0.0693 | 0.0766 | 0.1068 | 0.1115 | 0.6324 | 0.6008 | 0.0003 | 0.0004 | 0.0017 | 0.0125 | 0.0632 | 0.0921 | 0.0646 | 0.0980 | 0.6673 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 976 | 656 | | 13290 | 29012 | 350.5 | 83.54 | 117.42 | 202.47 | 252 | 284 | 306 | 327 | 348 | 369 | 393 | 419 | 457 | 0.0458 | 1328 | 1.206 | 145.66 | 51.35 | 3 | 0.0266 | 354 | 0.0009 | 33.81 | 7.228 | 0.1932 | 129853.0 | 50400000 | 20400000000 | 8570000000000 | 0.4626 | 0.1869 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0137 | 0.0009 | 0.0626 | 0.0154 | 0.1394 | 0.0357 | 0.1429 | 0.0364 | 0.1618 | 0.0560 | 0.4786 | 0.8556 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0047 | 0.0002 | 0.0239 | 0.0104 | 0.0583 | 0.0216 | 0.0527 | 0.0167 | 0.0693 | 0.0259 | 0.7910 | 0.9253 | 0.0016 | 0.0134 | 0.0070 | 0.0202 | 0.0147 | 0.0353 | 0.0609 | 0.1109 | 0.1230 | 0.1681 | 0.1707 | 0.1983 | 0.1145 | 0.1059 | 0.1486 | 0.1345 | 0.3589 | 0.2134 | 0.0002 | 0.0012 | 0.0066 | 0.0185 | 0.0678 | 0.1107 | 0.0917 | 0.1206 | 0.5827 | 6 | 7 | 9 | 10 | 12 | 24 | 88 | 206 | 406 | 0.1454 | 15.57 | 3.922 | 0.5837 | 54782.0 | 35700000 | 27800000000 | 24300000000000 | 0.5329 | 0.1352 | 0.0637 | 0.0030 | 0.1850 | 0.0394 | 0.2305 | 0.1421 | 0.1607 | 0.1285 | 0.1562 | 0.1739 | 0.0925 | 0.1834 | 0.0652 | 0.1156 | 0.0326 | 0.0940 | 0.0136 | 0.1201 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0018 | 0.0013 | 0.0098 | 0.0088 | 0.0421 | 0.0384 | 0.0678 | 0.0575 | 0.0453 | 0.0456 | 0.0680 | 0.0641 | 0.7645 | 0.7842 | 0.0000 | 0.0003 | 0.0004 | 0.0007 | 0.0017 | 0.0025 | 0.0116 | 0.0124 | 0.0523 | 0.0544 | 0.0850 | 0.0971 | 0.0615 | 0.0646 | 0.0847 | 0.0903 | 0.7028 | 0.6776 | 0.0004 | 0.0005 | 0.0019 | 0.0076 | 0.0494 | 0.0725 | 0.0487 | 0.0795 | 0.7395 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1089 | 808 | | 9170 | 24605 | 276.9 | 78.28 | 148.86 | 243.52 | 189 | 217 | 236 | 252 | 269 | 287 | 308 | 335 | 379 | 0.0478 | 1177 | 0.975 | 178.47 | 49.01 | 3 | 0.0484 | 444 | 0.0005 | 83.21 | 7.806 | 0.1414 | 82817.9 | 26600000 | 9120000000 | 3340000000000 | 0.3821 | 0.2526 | 0.0006 | 0.0000 | 0.0006 | 0.0003 | 0.0050 | 0.0006 | 0.0193 | 0.0027 | 0.0640 | 0.0215 | 0.1201 | 0.0404 | 0.1246 | 0.0400 | 0.1755 | 0.0620 | 0.4903 | 0.8326 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0081 | 0.0007 | 0.0235 | 0.0104 | 0.0451 | 0.0203 | 0.0512 | 0.0147 | 0.0759 | 0.0249 | 0.7939 | 0.9289 | 0.0042 | 0.0025 | 0.0052 | 0.0076 | 0.0157 | 0.0290 | 0.0408 | 0.0718 | 0.0963 | 0.1272 | 0.1387 | 0.1348 | 0.0994 | 0.1083 | 0.1251 | 0.1486 | 0.4746 | 0.3703 | 0.0014 | 0.0038 | 0.0107 | 0.0227 | 0.0568 | 0.0940 | 0.0838 | 0.1095 | 0.6172 | 10 | 13 | 15 | 19 | 31 | 61 | 125 | 239 | 462 | 0.0836 | 33.10 | 4.848 | 0.5636 | 81459.4 | 66300000 | 65000000000 | 71600000000000 | 0.3987 | 0.2387 | 0.0508 | 0.0023 | 0.1457 | 0.0182 | 0.2453 | 0.0872 | 0.1798 | 0.1196 | 0.1631 | 0.1870 | 0.1009 | 0.1877 | 0.0602 | 0.1413 | 0.0328 | 0.1066 | 0.0214 | 0.1501 | 0.0005 | 0.0000 | 0.0012 | 0.0005 | 0.0030 | 0.0019 | 0.0118 | 0.0111 | 0.0408 | 0.0392 | 0.0780 | 0.0652 | 0.0537 | 0.0500 | 0.0809 | 0.0683 | 0.7301 | 0.7639 | 0.0008 | 0.0004 | 0.0010 | 0.0022 | 0.0038 | 0.0053 | 0.0155 | 0.0224 | 0.0573 | 0.0634 | 0.0994 | 0.0936 | 0.0692 | 0.0729 | 0.0878 | 0.0951 | 0.6653 | 0.6447 | 0.0003 | 0.0010 | 0.0025 | 0.0126 | 0.0505 | 0.0841 | 0.0681 | 0.0859 | 0.6949 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 995 | 342 | | 564 | 6866 | 365.6 | 120.17 | 7.19 | 3.22 | 232 | 252 | 275 | 304 | 342 | 374 | 420 | 483 | 545 | 0.0756 | 519 | 0.945 | 118.23 | 29.12 | 4 | 0.5071 | 286 | 0.0058 | 7.76 | 5.422 | 0.3429 | 148105.0 | 65900000 | 31700000000 | 16200000000000 | 0.3696 | 0.2532 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0194 | 0.0133 | 0.1311 | 0.0421 | 0.2136 | 0.1242 | 0.1505 | 0.0643 | 0.1553 | 0.0931 | 0.3301 | 0.6630 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0083 | 0.0056 | 0.0500 | 0.0297 | 0.0667 | 0.0816 | 0.0444 | 0.0260 | 0.0639 | 0.0464 | 0.7667 | 0.8108 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0114 | 0.0195 | 0.0341 | 0.0779 | 0.0909 | 0.0974 | 0.1250 | 0.0649 | 0.0568 | 0.0779 | 0.1591 | 0.6623 | 0.5227 | 0.0000 | 0.0000 | 0.0000 | 0.0082 | 0.0617 | 0.0864 | 0.0453 | 0.0864 | 0.7119 | 4 | 4 | 5 | 6 | 7 | 7 | 8 | 10 | 12 | 0.0970 | 0.30 | 0.907 | 0.3778 | 62.0 | 621.741 | 7050.74 | 88336.7 | 0.5310 | 0.1386 | 0.0333 | 0.0083 | 0.0940 | 0.0274 | 0.1573 | 0.0625 | 0.2031 | 0.1170 | 0.2115 | 0.1983 | 0.1705 | 0.2399 | 0.0918 | 0.2042 | 0.0329 | 0.1141 | 0.0055 | 0.0284 | 0.0071 | 0.0004 | 0.0280 | 0.0051 | 0.0552 | 0.0227 | 0.0722 | 0.0545 | 0.0905 | 0.0935 | 0.1106 | 0.1358 | 0.1192 | 0.1525 | 0.1513 | 0.1718 | 0.3659 | 0.3639 | 0.0766 | 0.0859 | 0.0697 | 0.0791 | 0.0676 | 0.0846 | 0.0855 | 0.0784 | 0.0907 | 0.0914 | 0.1096 | 0.1153 | 0.1311 | 0.1535 | 0.1809 | 0.1869 | 0.1883 | 0.1248 | 0.0208 | 0.0594 | 0.0898 | 0.1063 | 0.1084 | 0.1039 | 0.0962 | 0.1215 | 0.2938 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 602 | 376 | | 1156 | 4064 | 474.2 | 143.37 | 10.35 | 8.30 | 315 | 334 | 360 | 391 | 431 | 490 | 562 | 644 | 697 | 0.0947 | 385 | 1.114 | 51.86 | 18.44 | 1 | 0.1211 | 140 | 0.0033 | 11.41 | 6.019 | 0.2906 | 245360.0 | 137000000 | 81700000000 | 51000000000000 | 0.3632 | 0.2648 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0025 | 0.0010 | 0.0327 | 0.0031 | 0.0955 | 0.0462 | 0.1382 | 0.0776 | 0.1709 | 0.0525 | 0.1608 | 0.0860 | 0.3995 | 0.7324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0009 | 0.0136 | 0.0017 | 0.0339 | 0.0304 | 0.0434 | 0.0470 | 0.0542 | 0.0261 | 0.0488 | 0.0487 | 0.8049 | 0.8452 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0118 | 0.0152 | 0.0559 | 0.0812 | 0.0588 | 0.0812 | 0.0559 | 0.0558 | 0.0765 | 0.1269 | 0.7412 | 0.6396 | 0.0000 | 0.0000 | 0.0000 | 0.0041 | 0.0412 | 0.0741 | 0.0329 | 0.0658 | 0.7819 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 15 | 0.0098 | 16.68 | 5.103 | 0.3379 | 176.1 | 6409.85 | 409709 | 33400000 | 0.4040 | 0.2136 | 0.0440 | 0.0038 | 0.1040 | 0.0105 | 0.1253 | 0.0332 | 0.2015 | 0.0514 | 0.2154 | 0.0867 | 0.1685 | 0.1160 | 0.1026 | 0.1499 | 0.0330 | 0.2376 | 0.0059 | 0.3110 | 0.0174 | 0.0014 | 0.0349 | 0.0052 | 0.0418 | 0.0193 | 0.0499 | 0.0293 | 0.0774 | 0.0503 | 0.1078 | 0.0748 | 0.1139 | 0.0871 | 0.1390 | 0.1550 | 0.4179 | 0.5775 | 0.0490 | 0.0472 | 0.0672 | 0.0407 | 0.0608 | 0.0650 | 0.0572 | 0.0911 | 0.0762 | 0.1382 | 0.1016 | 0.1154 | 0.1143 | 0.1073 | 0.1661 | 0.1268 | 0.3076 | 0.2683 | 0.0357 | 0.0421 | 0.0562 | 0.0761 | 0.0860 | 0.1094 | 0.1018 | 0.1281 | 0.3645 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1208 | 205 | | 6928 | 22071 | 341.7 | 78.65 | 108.42 | 121.55 | 242 | 273 | 297 | 318 | 338 | 358 | 381 | 406 | 444 | 0.0464 | 1025 | 0.821 | 127.02 | 32.56 | 1 | 0.0485 | 336 | 0.0010 | 44.29 | 7.174 | 0.1864 | 122938.0 | 46400000 | 18300000000 | 7530000000000 | 0.4442 | 0.2150 | 0.0005 | 0.0000 | 0.0009 | 0.0002 | 0.0054 | 0.0000 | 0.0289 | 0.0006 | 0.0774 | 0.0196 | 0.1548 | 0.0468 | 0.1496 | 0.0486 | 0.1733 | 0.0699 | 0.4092 | 0.8144 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0007 | 0.0000 | 0.0054 | 0.0001 | 0.0331 | 0.0134 | 0.0668 | 0.0319 | 0.0580 | 0.0246 | 0.0875 | 0.0358 | 0.7479 | 0.8940 | 0.0023 | 0.0124 | 0.0062 | 0.0155 | 0.0247 | 0.0310 | 0.0918 | 0.1455 | 0.1550 | 0.2012 | 0.1958 | 0.1827 | 0.1210 | 0.1022 | 0.1365 | 0.1269 | 0.2668 | 0.1827 | 0.0003 | 0.0015 | 0.0063 | 0.0271 | 0.0855 | 0.1353 | 0.1139 | 0.1317 | 0.4984 | 9 | 13 | 22 | 40 | 63 | 94 | 133 | 188 | 275 | 0.0306 | 13.52 | 5.344 | 0.4677 | 26526.8 | 9310000 | 4040000000 | 2020000000000 | 0.4133 | 0.2398 | 0.0339 | 0.0012 | 0.1396 | 0.0060 | 0.2401 | 0.0523 | 0.1953 | 0.1264 | 0.1400 | 0.1867 | 0.1291 | 0.2003 | 0.0747 | 0.1544 | 0.0331 | 0.1250 | 0.0141 | 0.1478 | 0.0006 | 0.0003 | 0.0014 | 0.0015 | 0.0028 | 0.0033 | 0.0161 | 0.0120 | 0.0537 | 0.0500 | 0.0941 | 0.0727 | 0.0729 | 0.0606 | 0.1043 | 0.0889 | 0.6540 | 0.7107 | 0.0007 | 0.0010 | 0.0031 | 0.0019 | 0.0047 | 0.0087 | 0.0232 | 0.0267 | 0.0849 | 0.0952 | 0.1181 | 0.1316 | 0.0860 | 0.0864 | 0.1223 | 0.1332 | 0.5570 | 0.5153 | 0.0002 | 0.0019 | 0.0039 | 0.0193 | 0.0666 | 0.1098 | 0.0796 | 0.1117 | 0.6070 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 266 | 832 | | 5052 | 10241 | 147.7 | 42.12 | 164.11 | 146.78 | 101 | 114 | 123 | 132 | 141 | 151 | 163 | 178 | 201 | 0.0842 | 862 | 1.052 | 93.96 | 28.02 | 1 | 0.0449 | 227 | 0.0015 | 34.75 | 6.782 | 0.2136 | 23601.0 | 4100000 | 775000000 | 160000000000 | 0.4351 | 0.2145 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0119 | 0.0004 | 0.0418 | 0.0025 | 0.1162 | 0.0275 | 0.1757 | 0.0555 | 0.1934 | 0.0737 | 0.1916 | 0.1095 | 0.2680 | 0.7309 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0002 | 0.0152 | 0.0008 | 0.0452 | 0.0174 | 0.0714 | 0.0304 | 0.0903 | 0.0289 | 0.1092 | 0.0521 | 0.6665 | 0.8702 | 0.0029 | 0.0073 | 0.0164 | 0.0171 | 0.0299 | 0.0465 | 0.0598 | 0.1345 | 0.1583 | 0.1736 | 0.1631 | 0.1760 | 0.1361 | 0.1100 | 0.1544 | 0.1271 | 0.2790 | 0.2078 | 0.0023 | 0.0041 | 0.0120 | 0.0322 | 0.0989 | 0.1427 | 0.1141 | 0.1542 | 0.4395 | 13 | 30 | 59 | 89 | 123 | 168 | 218 | 280 | 374 | 0.0051 | 65.13 | 6.912 | 0.2905 | 48476.3 | 18800000 | 8740000000 | 4630000000000 | 0.4979 | 0.1489 | 0.0225 | 0.0023 | 0.1359 | 0.0100 | 0.2239 | 0.0492 | 0.1838 | 0.0904 | 0.1746 | 0.1755 | 0.1352 | 0.2178 | 0.0803 | 0.1586 | 0.0331 | 0.1509 | 0.0106 | 0.1453 | 0.0000 | 0.0002 | 0.0014 | 0.0012 | 0.0045 | 0.0043 | 0.0163 | 0.0104 | 0.0593 | 0.0502 | 0.0964 | 0.0849 | 0.0821 | 0.0672 | 0.1055 | 0.0971 | 0.6345 | 0.6846 | 0.0014 | 0.0028 | 0.0029 | 0.0077 | 0.0063 | 0.0120 | 0.0284 | 0.0359 | 0.0831 | 0.0921 | 0.1287 | 0.1354 | 0.1006 | 0.1051 | 0.1284 | 0.1343 | 0.5201 | 0.4747 | 0.0002 | 0.0029 | 0.0059 | 0.0176 | 0.0699 | 0.1148 | 0.0813 | 0.1176 | 0.5899 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1246 | 581 | | 5724 | 10893 | 64.5 | 15.39 | 236.73 | 211.09 | 47 | 52 | 56 | 60 | 63 | 66 | 70 | 75 | 83 | 0.1007 | 1097 | 0.634 | 184.57 | 34.06 | 2 | 0.0786 | 450 | 0.0087 | 5.31 | 5.104 | 0.4181 | 4403.3 | 318930 | 24700000 | 2070000000 | 0.5293 | 0.1575 | 0.0011 | 0.0000 | 0.0029 | 0.0002 | 0.0149 | 0.0025 | 0.0344 | 0.0079 | 0.0831 | 0.0249 | 0.1403 | 0.0624 | 0.1470 | 0.0543 | 0.2027 | 0.0933 | 0.3736 | 0.7545 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0073 | 0.0014 | 0.0168 | 0.0048 | 0.0432 | 0.0173 | 0.0852 | 0.0464 | 0.0787 | 0.0324 | 0.1224 | 0.0582 | 0.6454 | 0.8396 | 0.0146 | 0.0251 | 0.0258 | 0.0282 | 0.0538 | 0.0219 | 0.0806 | 0.1066 | 0.1333 | 0.1818 | 0.1445 | 0.1630 | 0.1333 | 0.1348 | 0.1344 | 0.1285 | 0.2800 | 0.2100 | 0.0049 | 0.0125 | 0.0245 | 0.0623 | 0.1061 | 0.1303 | 0.1318 | 0.1477 | 0.3799 | 16 | 25 | 64 | 130 | 196 | 261 | 329 | 412 | 529 | 0.0116 | 86.41 | 6.934 | 0.2713 | 100595.0 | 54000000 | 33700000000 | 23600000000000 | 0.4576 | 0.1893 | 0.0320 | 0.0013 | 0.1436 | 0.0119 | 0.2339 | 0.0569 | 0.1831 | 0.1264 | 0.1737 | 0.1747 | 0.1260 | 0.2062 | 0.0652 | 0.1467 | 0.0332 | 0.1364 | 0.0094 | 0.1396 | 0.0005 | 0.0003 | 0.0027 | 0.0008 | 0.0034 | 0.0019 | 0.0151 | 0.0095 | 0.0589 | 0.0467 | 0.0943 | 0.0811 | 0.0861 | 0.0713 | 0.1289 | 0.1061 | 0.6100 | 0.6824 | 0.0003 | 0.0012 | 0.0025 | 0.0031 | 0.0076 | 0.0127 | 0.0227 | 0.0347 | 0.0882 | 0.1018 | 0.1372 | 0.1535 | 0.1175 | 0.1148 | 0.1447 | 0.1528 | 0.4794 | 0.4254 | 0.0017 | 0.0015 | 0.0040 | 0.0185 | 0.0733 | 0.1092 | 0.0968 | 0.1432 | 0.5521 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 503 | 432 | | 11808 | 33332 | 318.9 | 77.36 | 142.89 | 210.03 | 224 | 252 | 274 | 294 | 313 | 332 | 354 | 382 | 421 | 0.0347 | 1158 | 1.075 | 96.88 | 32.00 | 1 | 0.0204 | 241 | 0.0011 | 35.28 | 7.136 | 0.2018 | 107664.0 | 38400000 | 14400000000 | 5670000000000 | 0.4385 | 0.2096 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0068 | 0.0004 | 0.0240 | 0.0021 | 0.0823 | 0.0190 | 0.1435 | 0.0483 | 0.1432 | 0.0507 | 0.1608 | 0.0696 | 0.4388 | 0.8100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0071 | 0.0012 | 0.0317 | 0.0115 | 0.0656 | 0.0250 | 0.0600 | 0.0226 | 0.0788 | 0.0331 | 0.7553 | 0.9064 | 0.0047 | 0.0040 | 0.0064 | 0.0162 | 0.0180 | 0.0324 | 0.0588 | 0.1309 | 0.1171 | 0.1646 | 0.1656 | 0.2146 | 0.1257 | 0.1242 | 0.1416 | 0.1026 | 0.3621 | 0.2105 | 0.0020 | 0.0023 | 0.0069 | 0.0236 | 0.0705 | 0.1235 | 0.0941 | 0.1163 | 0.5608 | 6 | 7 | 9 | 11 | 20 | 67 | 166 | 292 | 458 | 0.1413 | 28.98 | 4.701 | 0.5652 | 64528.1 | 40100000 | 31100000000 | 29500000000000 | 0.4198 | 0.2297 | 0.0409 | 0.0008 | 0.1490 | 0.0130 | 0.2877 | 0.0770 | 0.1876 | 0.1317 | 0.1496 | 0.1991 | 0.0863 | 0.2098 | 0.0489 | 0.1278 | 0.0334 | 0.1018 | 0.0167 | 0.1390 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0007 | 0.0046 | 0.0041 | 0.0332 | 0.0264 | 0.0586 | 0.0502 | 0.0443 | 0.0368 | 0.0677 | 0.0562 | 0.7904 | 0.8252 | 0.0000 | 0.0002 | 0.0003 | 0.0008 | 0.0015 | 0.0014 | 0.0069 | 0.0086 | 0.0446 | 0.0485 | 0.0792 | 0.0935 | 0.0610 | 0.0660 | 0.0897 | 0.0966 | 0.7168 | 0.6842 | 0.0000 | 0.0006 | 0.0008 | 0.0069 | 0.0372 | 0.0677 | 0.0539 | 0.0771 | 0.7557 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 770 | 548 | | 4679 | 6669 | 137.8 | 37.32 | 193.13 | 136.78 | 97 | 107 | 115 | 123 | 132 | 140 | 151 | 165 | 188 | 0.1021 | 681 | 1.113 | 90.80 | 33.54 | 1 | 0.0524 | 245 | 0.0018 | 30.73 | 6.604 | 0.2167 | 20392.3 | 3250000 | 560000000 | 104000000000 | 0.4422 | 0.2057 | 0.0004 | 0.0000 | 0.0019 | 0.0000 | 0.0089 | 0.0007 | 0.0355 | 0.0024 | 0.1066 | 0.0257 | 0.1896 | 0.0591 | 0.1776 | 0.0651 | 0.1622 | 0.0905 | 0.3174 | 0.7565 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0043 | 0.0002 | 0.0097 | 0.0009 | 0.0441 | 0.0159 | 0.0819 | 0.0278 | 0.0802 | 0.0248 | 0.1044 | 0.0448 | 0.6745 | 0.8856 | 0.0054 | 0.0052 | 0.0086 | 0.0052 | 0.0119 | 0.0336 | 0.0627 | 0.1059 | 0.1568 | 0.2351 | 0.1859 | 0.2119 | 0.1092 | 0.0801 | 0.1557 | 0.1473 | 0.3038 | 0.1757 | 0.0015 | 0.0020 | 0.0085 | 0.0346 | 0.0989 | 0.1416 | 0.1145 | 0.1401 | 0.4583 | 42 | 70 | 97 | 128 | 161 | 203 | 250 | 305 | 391 | 0.0016 | 66.86 | 7.053 | 0.2296 | 56004.9 | 20500000 | 8680000000 | 4090000000000 | 0.5260 | 0.1564 | 0.0262 | 0.0016 | 0.1229 | 0.0056 | 0.2269 | 0.0334 | 0.1900 | 0.1091 | 0.1859 | 0.1851 | 0.1310 | 0.2201 | 0.0639 | 0.1584 | 0.0336 | 0.1421 | 0.0197 | 0.1445 | 0.0003 | 0.0007 | 0.0009 | 0.0007 | 0.0067 | 0.0024 | 0.0188 | 0.0163 | 0.0733 | 0.0544 | 0.1196 | 0.0928 | 0.0999 | 0.0728 | 0.1330 | 0.1079 | 0.5475 | 0.6521 | 0.0022 | 0.0017 | 0.0045 | 0.0063 | 0.0085 | 0.0150 | 0.0368 | 0.0600 | 0.1188 | 0.1298 | 0.1645 | 0.1997 | 0.1215 | 0.1298 | 0.1551 | 0.1558 | 0.3882 | 0.3018 | 0.0011 | 0.0032 | 0.0056 | 0.0275 | 0.0898 | 0.1479 | 0.1127 | 0.1437 | 0.4687 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 219 | 287 | | 7728 | 17407 | 156.2 | 33.25 | 151.14 | 137.62 | 117 | 127 | 135 | 144 | 153 | 161 | 171 | 184 | 201 | 0.0567 | 987 | 1.201 | 93.64 | 34.53 | 3 | 0.0299 | 231 | 0.0018 | 24.55 | 6.611 | 0.2248 | 25514.2 | 4360000 | 778000000 | 145000000000 | 0.3633 | 0.2904 | 0.0006 | 0.0000 | 0.0024 | 0.0001 | 0.0054 | 0.0000 | 0.0261 | 0.0015 | 0.0755 | 0.0144 | 0.1309 | 0.0416 | 0.1551 | 0.0359 | 0.1992 | 0.0585 | 0.4049 | 0.8479 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0028 | 0.0000 | 0.0126 | 0.0000 | 0.0327 | 0.0093 | 0.0547 | 0.0253 | 0.0662 | 0.0117 | 0.0973 | 0.0232 | 0.7321 | 0.9304 | 0.0082 | 0.0229 | 0.0202 | 0.0229 | 0.0306 | 0.0430 | 0.0866 | 0.1891 | 0.1262 | 0.1834 | 0.1688 | 0.2092 | 0.1494 | 0.1117 | 0.1501 | 0.1060 | 0.2599 | 0.1117 | 0.0017 | 0.0053 | 0.0122 | 0.0344 | 0.0780 | 0.1005 | 0.1089 | 0.1414 | 0.5176 | 25 | 37 | 53 | 75 | 105 | 143 | 192 | 255 | 344 | 0.0048 | 46.59 | 6.610 | 0.3171 | 41782.2 | 15900000 | 7490000000 | 4110000000000 | 0.4349 | 0.1994 | 0.0438 | 0.0012 | 0.1710 | 0.0129 | 0.2590 | 0.0915 | 0.1689 | 0.1419 | 0.1480 | 0.1792 | 0.0966 | 0.1929 | 0.0651 | 0.1402 | 0.0336 | 0.1134 | 0.0140 | 0.1269 | 0.0006 | 0.0000 | 0.0016 | 0.0011 | 0.0035 | 0.0031 | 0.0209 | 0.0133 | 0.0660 | 0.0570 | 0.1224 | 0.0997 | 0.0905 | 0.0754 | 0.1165 | 0.0996 | 0.5779 | 0.6509 | 0.0004 | 0.0013 | 0.0043 | 0.0044 | 0.0077 | 0.0109 | 0.0342 | 0.0455 | 0.0992 | 0.1166 | 0.1564 | 0.1705 | 0.1123 | 0.1236 | 0.1422 | 0.1484 | 0.4433 | 0.3789 | 0.0009 | 0.0019 | 0.0058 | 0.0251 | 0.0859 | 0.1396 | 0.1007 | 0.1336 | 0.5064 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 547 | 289 | | 11285 | 27072 | 244.5 | 58.73 | 197.38 | 232.26 | 172 | 193 | 209 | 224 | 239 | 255 | 274 | 296 | 325 | 0.0436 | 1181 | 1.186 | 113.74 | 45.89 | 1 | 0.0262 | 296 | 0.0006 | 59.04 | 7.598 | 0.1608 | 63242.6 | 17200000 | 4920000000 | 1470000000000 | 0.4595 | 0.1977 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0003 | 0.0222 | 0.0030 | 0.0838 | 0.0183 | 0.1665 | 0.0428 | 0.1519 | 0.0447 | 0.1695 | 0.0687 | 0.4015 | 0.8221 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0009 | 0.0000 | 0.0056 | 0.0015 | 0.0329 | 0.0117 | 0.0689 | 0.0232 | 0.0624 | 0.0202 | 0.0836 | 0.0302 | 0.7454 | 0.9132 | 0.0042 | 0.0118 | 0.0042 | 0.0251 | 0.0161 | 0.0340 | 0.0589 | 0.0991 | 0.1158 | 0.1731 | 0.1866 | 0.1864 | 0.1001 | 0.1080 | 0.1387 | 0.1391 | 0.3753 | 0.2234 | 0.0010 | 0.0019 | 0.0079 | 0.0250 | 0.0784 | 0.1238 | 0.0992 | 0.1291 | 0.5338 | 14 | 18 | 26 | 48 | 94 | 162 | 255 | 375 | 541 | 0.0240 | 59.33 | 6.100 | 0.4045 | 92900.8 | 59800000 | 46700000000 | 42500000000000 | 0.3821 | 0.2440 | 0.0415 | 0.0013 | 0.1747 | 0.0119 | 0.3178 | 0.1184 | 0.1407 | 0.1403 | 0.1199 | 0.1896 | 0.0884 | 0.1946 | 0.0465 | 0.1232 | 0.0336 | 0.1013 | 0.0369 | 0.1196 | 0.0001 | 0.0002 | 0.0000 | 0.0003 | 0.0009 | 0.0010 | 0.0080 | 0.0057 | 0.0480 | 0.0394 | 0.0973 | 0.0776 | 0.0603 | 0.0509 | 0.0905 | 0.0756 | 0.6949 | 0.7492 | 0.0002 | 0.0004 | 0.0020 | 0.0014 | 0.0027 | 0.0026 | 0.0159 | 0.0171 | 0.0664 | 0.0775 | 0.1207 | 0.1335 | 0.0813 | 0.0857 | 0.1106 | 0.1232 | 0.6001 | 0.5585 | 0.0001 | 0.0006 | 0.0019 | 0.0122 | 0.0586 | 0.1142 | 0.0705 | 0.1007 | 0.6412 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 857 | 519 | | 7896 | 25086 | 549.1 | 111.64 | 115.29 | 108.29 | 407 | 452 | 487 | 515 | 543 | 571 | 603 | 640 | 694 | 0.0453 | 1137 | 0.998 | 121.50 | 33.97 | 1 | 0.0384 | 303 | 0.0006 | 71.62 | 7.693 | 0.1462 | 313964.0 | 187000000 | 115000000000 | 73300000000000 | 0.4442 | 0.2062 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0000 | 0.0110 | 0.0013 | 0.0526 | 0.0162 | 0.1198 | 0.0335 | 0.1264 | 0.0258 | 0.1582 | 0.0429 | 0.5295 | 0.8802 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0000 | 0.0247 | 0.0109 | 0.0576 | 0.0223 | 0.0544 | 0.0138 | 0.0738 | 0.0246 | 0.7850 | 0.9284 | 0.0055 | 0.0067 | 0.0079 | 0.0134 | 0.0259 | 0.0235 | 0.0715 | 0.0705 | 0.1155 | 0.1779 | 0.1595 | 0.2315 | 0.1147 | 0.1409 | 0.1304 | 0.1342 | 0.3692 | 0.2013 | 0.0003 | 0.0021 | 0.0045 | 0.0279 | 0.0760 | 0.1244 | 0.0942 | 0.1323 | 0.5384 | 14 | 19 | 30 | 51 | 80 | 116 | 158 | 205 | 271 | 0.0163 | 18.42 | 5.849 | 0.4162 | 25016.0 | 7180000 | 2480000000 | 993000000000 | 0.4965 | 0.1507 | 0.0497 | 0.0008 | 0.2062 | 0.0128 | 0.2854 | 0.1255 | 0.1474 | 0.1729 | 0.1169 | 0.1868 | 0.0873 | 0.1793 | 0.0490 | 0.1096 | 0.0336 | 0.0972 | 0.0245 | 0.1151 | 0.0003 | 0.0000 | 0.0008 | 0.0004 | 0.0022 | 0.0018 | 0.0130 | 0.0103 | 0.0633 | 0.0528 | 0.1135 | 0.0937 | 0.0729 | 0.0627 | 0.1138 | 0.0990 | 0.6201 | 0.6793 | 0.0006 | 0.0004 | 0.0013 | 0.0031 | 0.0045 | 0.0078 | 0.0266 | 0.0355 | 0.0880 | 0.1026 | 0.1507 | 0.1609 | 0.0929 | 0.1075 | 0.1339 | 0.1393 | 0.5016 | 0.4429 | 0.0004 | 0.0013 | 0.0028 | 0.0194 | 0.0737 | 0.1338 | 0.0833 | 0.1256 | 0.5598 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 262 | 293 | | 4620 | 9068 | 125.3 | 34.05 | 229.46 | 230.57 | 87 | 97 | 105 | 113 | 120 | 129 | 139 | 150 | 170 | 0.0786 | 713 | 0.960 | 89.94 | 24.74 | 1 | 0.0455 | 210 | 0.0019 | 28.55 | 6.554 | 0.2287 | 16849.6 | 2440000 | 379000000 | 63400000000 | 0.4415 | 0.2073 | 0.0011 | 0.0000 | 0.0034 | 0.0000 | 0.0134 | 0.0020 | 0.0550 | 0.0044 | 0.1237 | 0.0285 | 0.1753 | 0.0668 | 0.1760 | 0.0717 | 0.1955 | 0.1060 | 0.2566 | 0.7207 | 0.0003 | 0.0000 | 0.0014 | 0.0000 | 0.0025 | 0.0002 | 0.0129 | 0.0016 | 0.0525 | 0.0172 | 0.0784 | 0.0347 | 0.0865 | 0.0293 | 0.1231 | 0.0528 | 0.6423 | 0.8643 | 0.0053 | 0.0075 | 0.0149 | 0.0151 | 0.0351 | 0.0327 | 0.0904 | 0.1332 | 0.1521 | 0.2010 | 0.1883 | 0.2161 | 0.1223 | 0.1156 | 0.1383 | 0.1231 | 0.2532 | 0.1558 | 0.0024 | 0.0043 | 0.0097 | 0.0454 | 0.0985 | 0.1424 | 0.1318 | 0.1544 | 0.4112 | 25 | 41 | 69 | 102 | 141 | 203 | 283 | 398 | 568 | 0.0094 | 60.31 | 6.466 | 0.3430 | 105806.0 | 66900000 | 50200000000 | 42000000000000 | 0.4589 | 0.1675 | 0.0392 | 0.0005 | 0.1446 | 0.0095 | 0.2500 | 0.0695 | 0.1940 | 0.1304 | 0.1567 | 0.1823 | 0.1063 | 0.1972 | 0.0653 | 0.1403 | 0.0336 | 0.1173 | 0.0103 | 0.1530 | 0.0003 | 0.0002 | 0.0005 | 0.0022 | 0.0021 | 0.0028 | 0.0152 | 0.0130 | 0.0627 | 0.0430 | 0.0970 | 0.0745 | 0.0807 | 0.0682 | 0.1031 | 0.0917 | 0.6385 | 0.7043 | 0.0000 | 0.0004 | 0.0036 | 0.0013 | 0.0053 | 0.0101 | 0.0246 | 0.0331 | 0.0891 | 0.0947 | 0.1162 | 0.1404 | 0.1023 | 0.1086 | 0.1276 | 0.1379 | 0.5314 | 0.4736 | 0.0015 | 0.0024 | 0.0037 | 0.0198 | 0.0678 | 0.1110 | 0.0916 | 0.1199 | 0.5823 |