High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 910 235 image if available 5650 9484 613.1 99.25 15.85 17.71 472 537 575 601 623 643 663 690 733 0.0777 737 0.760 87.05 15.26 1 0.0388 219 0.0011 30.87 7.107 0.2252 385716.0
248000000
163000000000
109000000000000
0.3922 0.2485 0.0005 0.0000 0.0002 0.0000 0.0016 0.0000 0.0043 0.0007 0.0256 0.0133 0.0488 0.0204 0.0442 0.0136 0.0551 0.0226 0.8197 0.9294 0.0002 0.0000 0.0000 0.0000 0.0000 0.0000 0.0012 0.0007 0.0151 0.0133 0.0258 0.0204 0.0208 0.0122 0.0270 0.0190 0.9099 0.9344 0.0036 0.2000 0.0145 0.8000 0.0163 0.0000 0.0435 0.0000 0.0870 0.0000 0.1431 0.0000 0.0833 0.0000 0.1105 0.0000 0.4982 0.0000 0.0019 0.0019 0.0061 0.0129 0.0399 0.0633 0.0672 0.0987 0.7081 5 7 8 9 11 13 15 20 32 0.2512 0.44 1.751 0.7487 564.9
50306.4
9130000
2400000000
0.5918 0.0979 0.0534 0.0357 0.0820 0.0510 0.0996 0.0522 0.1245 0.0695 0.1572 0.0948 0.1789 0.1024 0.1727 0.1371 0.1011 0.1779 0.0306 0.2793 0.0244 0.0248 0.0307 0.0322 0.0359 0.0315 0.0432 0.0424 0.0663 0.0619 0.0788 0.0696 0.0772 0.0803 0.1043 0.1080 0.5391 0.5493 0.0219 0.0129 0.0172 0.0233 0.0256 0.0259 0.0339 0.0291 0.0516 0.0505 0.0793 0.0627 0.0652 0.0524 0.0814 0.0996 0.6239 0.6436 0.0286 0.0414 0.0352 0.0447 0.0521 0.0660 0.0663 0.1015 0.5642
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 954 880 image if available 1679 5441 653.6 119.11 75.62 146.47 478 542 591 627 661 696 731 766 800 0.0884 481 0.755 132.23 36.35 1 0.2287 384 0.0009 82.04 7.094 0.1478 441315.0
307000000
218000000000
159000000000000
0.3946 0.2342 0.0000 0.0000 0.0000 0.0000 0.0009 0.0000 0.0086 0.0018 0.0522 0.0283 0.0779 0.0361 0.0693 0.0307 0.1259 0.0451 0.6652 0.8581 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0021 0.0018 0.0313 0.0281 0.0392 0.0329 0.0271 0.0257 0.0499 0.0418 0.8504 0.8698 0.0042 0.0000 0.0169 0.0000 0.0254 0.0000 0.0424 0.0000 0.0890 0.0000 0.1271 0.0000 0.1144 0.0000 0.1271 0.0000 0.4534 0.0000 0.0011 0.0011 0.0034 0.0103 0.0525 0.0627 0.0490 0.0855 0.7343 7 9 11 13 17 28 60 104 173 0.0733 1.76 2.761 0.5531 27168.4
17800000
14800000000
13800000000000
0.4065 0.2202 0.0128 0.0026 0.0204 0.0102 0.0510 0.0269 0.1301 0.0409 0.1913 0.0882 0.2041 0.1317 0.1735 0.1228 0.1301 0.2008 0.0867 0.3760 0.0000 0.0000 0.0000 0.0016 0.0018 0.0027 0.0092 0.0070 0.0308 0.0271 0.0450 0.0411 0.0431 0.0319 0.0603 0.0541 0.8097 0.8343 0.0008 0.0009 0.0000 0.0019 0.0049 0.0075 0.0130 0.0160 0.0381 0.0479 0.0657 0.0695 0.0536 0.0638 0.0869 0.0892 0.7370 0.7033 0.0000 0.0063 0.0042 0.0105 0.0359 0.0450 0.0549 0.0703 0.7729
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 613 713 image if available 713 1229 91.3 14.01 6.39 2.54 72 77 83 87 92 96 100 104 109 0.2522 310 1.070 24.52 7.28 1 0.0884 63 0.0680 0.69 2.897 0.7227 8522.9
813628
79300000
7870000000
0.3848 0.2534 0.0000 0.0000 0.0053 0.0000 0.0123 0.0014 0.0247 0.0014 0.0670 0.0492 0.0917 0.0646 0.1217 0.0478 0.1711 0.0772 0.5062 0.7584 0.0000 0.0000 0.0048 0.0000 0.0095 0.0014 0.0127 0.0014 0.0523 0.0491 0.0507 0.0645 0.0555 0.0477 0.0777 0.0659 0.7369 0.7700 0.0156 1.0000 0.0938 0.0000 0.0625 0.0000 0.1406 0.0000 0.2344 0.0000 0.1875 0.0000 0.0781 0.0000 0.1094 0.0000 0.0781 0.0000 0.0053 0.0107 0.0213 0.0373 0.0613 0.0587 0.0827 0.1280 0.5947 3 5 5 6 6 7 7 8 9 0.0448 0.26 0.778 0.2347 47.3
411.762
4361.59
56996.9
0.5177 0.1432 0.0094 0.0021 0.0336 0.0064 0.0983 0.0364 0.1023 0.0621 0.1911 0.1424 0.2248 0.1681 0.1736 0.2141 0.1279 0.2473 0.0390 0.1210 0.0000 0.0000 0.0048 0.0009 0.0183 0.0109 0.0502 0.0263 0.1187 0.1069 0.1525 0.1295 0.2008 0.1639 0.2346 0.2473 0.2201 0.3143 0.1365 0.2588 0.2048 0.1882 0.1468 0.1353 0.1433 0.1353 0.1502 0.0588 0.0785 0.0471 0.0512 0.0529 0.0375 0.0412 0.0512 0.0824 0.0038 0.0368 0.0722 0.1293 0.1812 0.1787 0.1496 0.1546 0.0938
Hs 578T A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 992 554 image if available 458 453 58.6 18.24 15.98 3.18 38 42 46 52 56 61 66 72 84 0.4040 183 0.735 110.07 27.07 1 0.6135 281 0.0119 5.25 4.713 0.4351 3769.0
265175
20300000
1680000000
0.3546 0.2594 0.0000 0.0000 0.0199 0.0000 0.0448 0.0000 0.0597 0.0052 0.1294 0.0735 0.2139 0.1417 0.1791 0.0761 0.1343 0.1155 0.2189 0.5879 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0164 0.0046 0.0656 0.0371 0.1049 0.0928 0.0721 0.0278 0.0951 0.0603 0.6459 0.7773 0.0096 0.0000 0.0000 0.0000 0.0096 0.0600 0.0673 0.1800 0.2019 0.1000 0.1731 0.2800 0.0865 0.1400 0.1635 0.0600 0.2885 0.1800 0.0000 0.0000 0.0048 0.0335 0.1435 0.1483 0.1100 0.1627 0.3971 12 13 14 15 16 17 17 18 20 0.8738 0.06 0.306 0.9702 265.5
4574.87
81636.7
1510000
0.5349 0.1049 0.0031 0.0000 0.0217 0.0000 0.0683 0.0046 0.1211 0.0207 0.2050 0.1359 0.1739 0.1544 0.1739 0.1613 0.1801 0.1521 0.0528 0.3710 0.0026 0.0000 0.0078 0.0000 0.0284 0.0045 0.0413 0.0089 0.1835 0.1250 0.1550 0.1473 0.1576 0.1518 0.1938 0.1384 0.2300 0.4241 0.2923 0.5000 0.1846 0.2143 0.1385 0.2143 0.1846 0.0714 0.1077 0.0000 0.0615 0.0000 0.0308 0.0000 0.0000 0.0000 0.0000 0.0000 0.0195 0.0586 0.1328 0.1445 0.1758 0.1680 0.1367 0.1055 0.0586
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 472 429 image if available 2702 12483 298.7 39.90 33.75 65.19 243 264 280 292 303 312 321 330 347 0.0569 710 0.587 156.06 44.65 2 0.1991 538 0.0038 12.01 5.909 0.3178 90794.9
28100000
8800000000
2800000000000
0.4181 0.2189 0.0000 0.0000 0.0000 0.0000 0.0004 0.0000 0.0082 0.0004 0.0381 0.0222 0.0559 0.0359 0.0563 0.0200 0.0858 0.0333 0.7552 0.8882 0.0000 0.0000 0.0000 0.0000 0.0004 0.0000 0.0045 0.0004 0.0288 0.0222 0.0365 0.0359 0.0337 0.0200 0.0483 0.0333 0.8479 0.8882 0.0064 0.0000 0.0446 0.0000 0.0318 0.0000 0.1019 0.0000 0.1338 0.0000 0.1656 0.0000 0.1529 0.0000 0.1338 0.0000 0.2293 0.0000 0.0000 0.0014 0.0095 0.0210 0.0535 0.0947 0.0947 0.1238 0.6015 7 9 10 11 13 16 21 29 72 0.2585 2.84 2.563 0.8124 5388.1
1890000
937000000
558000000000
0.6147 0.0974 0.0312 0.0161 0.0775 0.0194 0.0763 0.0317 0.1329 0.0506 0.1699 0.1013 0.1642 0.1079 0.1780 0.1240 0.1202 0.1614 0.0497 0.3876 0.0063 0.0091 0.0118 0.0101 0.0074 0.0133 0.0221 0.0195 0.0505 0.0405 0.0660 0.0549 0.0705 0.0613 0.0989 0.0965 0.6665 0.6947 0.0038 0.0000 0.0065 0.0043 0.0076 0.0049 0.0244 0.0232 0.0455 0.0452 0.0764 0.0757 0.0585 0.0550 0.0748 0.0794 0.7026 0.7123 0.0014 0.0082 0.0096 0.0227 0.0537 0.0719 0.0637 0.0928 0.6761
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 259 595 image if available 3281 8845 537.2 98.78 47.70 69.98 406 455 487 513 535 555 578 608 681 0.0684 605 1.005 109.84 37.48 2 0.0884 290 0.0012 24.77 6.942 0.2330 298323.0
171000000
101000000000
61500000000000
0.4559 0.1915 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0076 0.0006 0.0295 0.0159 0.0565 0.0312 0.0510 0.0243 0.0674 0.0328 0.7880 0.8952 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0039 0.0006 0.0159 0.0128 0.0297 0.0253 0.0244 0.0131 0.0304 0.0186 0.8956 0.9295 0.0066 0.0137 0.0088 0.0274 0.0243 0.0959 0.0133 0.0959 0.0575 0.2055 0.0973 0.1507 0.0619 0.1096 0.0841 0.1507 0.6460 0.1507 0.0012 0.0000 0.0025 0.0204 0.0532 0.0835 0.0884 0.1070 0.6438 8 9 11 12 14 19 46 78 131 0.2066 2.60 3.143 0.7617 7171.8
1810000
603000000
239000000000
0.5155 0.1378 0.0352 0.0029 0.0580 0.0155 0.0890 0.0638 0.1201 0.0629 0.1532 0.0977 0.1636 0.1460 0.1822 0.1199 0.1387 0.1586 0.0600 0.3327 0.0007 0.0007 0.0014 0.0020 0.0021 0.0029 0.0064 0.0085 0.0152 0.0186 0.0258 0.0232 0.0237 0.0235 0.0488 0.0405 0.8759 0.8803 0.0017 0.0015 0.0009 0.0039 0.0064 0.0064 0.0111 0.0148 0.0273 0.0261 0.0413 0.0542 0.0388 0.0473 0.0725 0.0719 0.8001 0.7740 0.0008 0.0008 0.0035 0.0096 0.0207 0.0261 0.0337 0.0560 0.8489
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 273 873 image if available 959 20054 113.6 15.41 28.35 38.32 95 99 103 107 113 117 121 127 135 0.0524 1050 1.034 39.40 13.04 0 0.1064 102 0.0763 0.50 2.832 0.7708 13136.1
1550000
186000000
22800000000
0.4056 0.2400 0.0012 0.0000 0.0036 0.0010 0.0083 0.0031 0.0154 0.0073 0.0473 0.0241 0.0746 0.0640 0.0734 0.0325 0.1006 0.0598 0.6757 0.8080 0.0011 0.0000 0.0032 0.0010 0.0076 0.0031 0.0108 0.0073 0.0314 0.0229 0.0541 0.0615 0.0400 0.0250 0.0639 0.0532 0.7879 0.8259 0.0000 0.0000 0.0127 0.1667 0.0506 0.0000 0.1013 0.5000 0.1266 0.3333 0.1392 0.0000 0.1266 0.0000 0.1266 0.0000 0.3165 0.0000 0.0022 0.0043 0.0152 0.0260 0.0390 0.0758 0.0736 0.1017 0.6623 11 13 15 17 20 22 26 31 40 0.3245 0.91 1.880 0.8551 2272.4
507754
174000000
71000000000
0.5696 0.1296 0.0433 0.0176 0.0600 0.0218 0.0785 0.0264 0.1039 0.0386 0.1265 0.0642 0.1678 0.0809 0.1887 0.1079 0.1421 0.1846 0.0893 0.4581 0.0240 0.0144 0.0282 0.0178 0.0330 0.0204 0.0353 0.0280 0.0502 0.0467 0.0618 0.0603 0.0746 0.0721 0.1061 0.1150 0.5867 0.6253 0.0284 0.0348 0.0315 0.0221 0.0495 0.0172 0.0486 0.0255 0.0769 0.0594 0.0874 0.0790 0.0867 0.0795 0.1126 0.1286 0.4784 0.5540 0.0222 0.0261 0.0286 0.0380 0.0551 0.0752 0.0968 0.1505 0.5076
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 1002 903 image if available 2590 6854 671.8 130.82 57.85 118.91 504 556 597 632 666 700 730 773 852 0.0926 635 0.749 181.18 45.31 2 0.1853 480 0.0008 66.05 7.317 0.1448 468423.0
339000000
253000000000
195000000000000
0.4212 0.2260 0.0000 0.0000 0.0000 0.0000 0.0006 0.0004 0.0062 0.0020 0.0506 0.0208 0.1069 0.0425 0.0771 0.0261 0.1187 0.0357 0.6398 0.8725 0.0000 0.0000 0.0000 0.0000 0.0000 0.0004 0.0032 0.0008 0.0272 0.0159 0.0614 0.0348 0.0378 0.0147 0.0591 0.0224 0.8113 0.9111 0.0051 0.0000 0.0000 0.0000 0.0103 0.0220 0.0282 0.0879 0.0872 0.1209 0.1385 0.1758 0.0923 0.1868 0.1256 0.1538 0.5128 0.2527 0.0008 0.0000 0.0040 0.0217 0.0593 0.1051 0.0842 0.1043 0.6207 10 12 13 16 22 33 42 64 129 0.1077 12.25 3.455 0.7303 17483.7
14800000
20400000000
35900000000000
0.6243 0.0943 0.0239 0.0079 0.0613 0.0126 0.0733 0.0238 0.1346 0.0516 0.1891 0.0827 0.1704 0.1263 0.1891 0.1468 0.1193 0.1640 0.0392 0.3843 0.0054 0.0046 0.0113 0.0057 0.0097 0.0092 0.0199 0.0218 0.0485 0.0402 0.0889 0.0766 0.0711 0.0808 0.0867 0.0938 0.6584 0.6673 0.0039 0.0018 0.0024 0.0027 0.0087 0.0064 0.0221 0.0282 0.0559 0.0645 0.1087 0.1064 0.0693 0.0709 0.0969 0.0982 0.6320 0.6209 0.0026 0.0066 0.0066 0.0178 0.0540 0.0949 0.0639 0.0988 0.6548
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 365 353 image if available 5969 9686 532.6 131.58 28.76 57.02 329 402 483 536 572 597 619 644 676 0.0840 814 1.039 109.33 39.70 3 0.0476 284 0.0007 61.44 7.562 0.1890 300963.0
177000000
107000000000
65900000000000
0.4153 0.2188 0.0006 0.0000 0.0018 0.0000 0.0036 0.0002 0.0109 0.0011 0.0555 0.0200 0.0772 0.0344 0.0832 0.0215 0.1212 0.0340 0.6460 0.8888 0.0000 0.0000 0.0000 0.0000 0.0002 0.0002 0.0015 0.0011 0.0246 0.0200 0.0316 0.0336 0.0250 0.0204 0.0396 0.0310 0.8774 0.8937 0.0055 0.0000 0.0071 0.0000 0.0188 1.0000 0.0290 0.0000 0.0565 0.0000 0.0863 0.0000 0.0847 0.0000 0.1145 0.0000 0.5976 0.0000 0.0003 0.0000 0.0019 0.0047 0.0314 0.0394 0.0411 0.0607 0.8205 8 10 11 13 16 21 27 36 51 0.1769 0.75 1.769 0.6861 4078.2
2130000
1520000000
1200000000000
0.5279 0.1420 0.0341 0.0214 0.0384 0.0239 0.0803 0.0306 0.0852 0.0415 0.1165 0.0580 0.1541 0.0685 0.1925 0.0928 0.1996 0.1557 0.0994 0.5076 0.0086 0.0112 0.0106 0.0098 0.0185 0.0121 0.0222 0.0179 0.0376 0.0331 0.0539 0.0414 0.0587 0.0485 0.0952 0.0713 0.6946 0.7548 0.0124 0.0117 0.0133 0.0123 0.0143 0.0178 0.0219 0.0270 0.0505 0.0596 0.0657 0.0713 0.0634 0.0774 0.0991 0.1167 0.6594 0.6063 0.0141 0.0137 0.0213 0.0260 0.0416 0.0513 0.0604 0.0853 0.6863
SK-BR-3 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 1130 267 image if available 5490 23038 164.0 66.56 28.31 61.33 83 103 121 140 156 173 190 215 271 0.0512 1180 0.983 61.59 20.03 5 0.0288 158 0.0023 6.37 6.316 0.3881 31316.4
6760000
1600000000
408000000000
0.3733 0.2534 0.0000 0.0000 0.0019 0.0025 0.0077 0.0028 0.0178 0.0083 0.0548 0.0230 0.0836 0.0418 0.1000 0.0452 0.1629 0.0593 0.5714 0.8171 0.0000 0.0000 0.0011 0.0015 0.0023 0.0018 0.0056 0.0051 0.0158 0.0124 0.0237 0.0218 0.0259 0.0218 0.0440 0.0294 0.8816 0.9062 0.0027 0.0011 0.0075 0.0054 0.0137 0.0087 0.0239 0.0130 0.0321 0.0369 0.0498 0.0510 0.0546 0.0304 0.0539 0.0542 0.7618 0.7993 0.0000 0.0012 0.0056 0.0164 0.0308 0.0504 0.0496 0.0712 0.7747 7 9 10 12 13 15 18 25 46 0.1947 4.25 2.622 0.7761 4562.8
1730000
803000000
408000000000
0.5689 0.1210 0.0523 0.0587 0.0562 0.0581 0.0812 0.0637 0.1251 0.0665 0.1413 0.0729 0.1613 0.0863 0.1935 0.0999 0.1268 0.1500 0.0623 0.3441 0.0140 0.0361 0.0138 0.0353 0.0177 0.0353 0.0272 0.0346 0.0400 0.0414 0.0560 0.0533 0.0641 0.0585 0.0971 0.0880 0.6701 0.6175 0.0057 0.0047 0.0093 0.0061 0.0131 0.0140 0.0191 0.0201 0.0508 0.0635 0.0669 0.0793 0.0770 0.0840 0.1123 0.1231 0.6459 0.6053 0.0104 0.0106 0.0164 0.0205 0.0425 0.0614 0.0594 0.1068 0.6718
BT-20 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 340 406 image if available 471 6514 857.4 228.67 9.61 2.99 549 627 690 770 842 920 1002 1103 1189 0.0711 463 1.310 25.32 10.63 1 0.1423 67 0.0025 78.35 6.025 0.1012 787377.0
767000000
784000000000
832000000000000
0.3659 0.2545 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0099 0.0024 0.1034 0.0622 0.2512 0.0909 0.1281 0.0646 0.1823 0.0933 0.3251 0.6866 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0061 0.0022 0.0515 0.0500 0.0879 0.0609 0.0424 0.0391 0.0515 0.0543 0.7606 0.7935 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0079 0.0476 0.0787 0.1667 0.1496 0.1667 0.0315 0.0952 0.1260 0.1667 0.6063 0.3571 0.0000 0.0000 0.0000 0.0089 0.0536 0.1161 0.0402 0.0714 0.7098 6 7 8 9 9 10 11 12 13 0.0120 10.83 4.800 0.3191 101.2
1165.12
14657.4
201923
0.4760 0.1625 0.0062 0.0009 0.0309 0.0025 0.0752 0.0063 0.1498 0.0201 0.2096 0.0366 0.2372 0.0807 0.1938 0.1532 0.0783 0.3133 0.0190 0.3862 0.0016 0.0000 0.0096 0.0007 0.0200 0.0031 0.0446 0.0111 0.0824 0.0214 0.1177 0.0415 0.1815 0.0663 0.2235 0.1853 0.3192 0.6707 0.1143 0.2295 0.1414 0.1525 0.1455 0.1311 0.1299 0.0803 0.1225 0.0738 0.1049 0.0754 0.0683 0.0623 0.0751 0.1049 0.0981 0.0902 0.0313 0.0568 0.1064 0.1471 0.1279 0.1328 0.1432 0.1233 0.1312
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 886 459 image if available 3618 10342 579.4 120.00 16.41 14.61 402 502 541 570 596 621 644 667 707 0.0617 638 0.872 72.47 21.02 4 0.0506 183 0.0010 57.19 7.152 0.1994 350122.0
218000000
140000000000
91900000000000
0.4429 0.2126 0.0004 0.0000 0.0000 0.0003 0.0008 0.0006 0.0086 0.0012 0.0409 0.0173 0.0601 0.0352 0.0530 0.0212 0.0823 0.0391 0.7539 0.8852 0.0000 0.0000 0.0000 0.0003 0.0000 0.0006 0.0013 0.0009 0.0167 0.0167 0.0279 0.0301 0.0196 0.0140 0.0382 0.0289 0.8963 0.9084 0.0088 0.0000 0.0044 0.0980 0.0199 0.0000 0.0508 0.0980 0.1258 0.1569 0.1523 0.1765 0.1192 0.0588 0.1501 0.1373 0.3687 0.2745 0.0000 0.0005 0.0063 0.0146 0.0466 0.0777 0.0670 0.0869 0.7005 6 8 9 11 13 15 17 20 29 0.2798 0.41 1.932 0.8610 482.7
28156.6
2820000
388000000
0.4309 0.2072 0.0435 0.0205 0.0470 0.0372 0.0509 0.0455 0.0895 0.0516 0.1126 0.0612 0.1545 0.0846 0.2073 0.1008 0.1905 0.1706 0.1043 0.4280 0.0225 0.0151 0.0206 0.0257 0.0213 0.0301 0.0324 0.0319 0.0506 0.0421 0.0689 0.0635 0.0845 0.0648 0.1386 0.1026 0.5606 0.6242 0.0382 0.0267 0.0326 0.0130 0.0336 0.0298 0.0424 0.0360 0.0559 0.0477 0.0634 0.0701 0.0662 0.0775 0.1058 0.0967 0.5620 0.6026 0.0209 0.0300 0.0386 0.0551 0.0695 0.0973 0.0921 0.1086 0.4879
BT-20 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 765 448 image if available 1036 4704 600.2 210.48 6.20 1.84 332 391 444 509 577 659 743 818 904 0.0897 422 1.225 53.31 21.95 1 0.1332 138 0.0016 24.08 6.554 0.2404 404516.0
298000000
234000000000
192000000000000
0.3419 0.2894 0.0000 0.0000 0.0000 0.0000 0.0000 0.0014 0.0031 0.0043 0.1242 0.0558 0.2329 0.1016 0.1304 0.0629 0.1739 0.0801 0.3354 0.6938 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0011 0.0392 0.0339 0.0633 0.0532 0.0271 0.0271 0.0542 0.0407 0.8163 0.8439 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0058 0.0324 0.0585 0.0649 0.0848 0.1135 0.0409 0.0757 0.0673 0.0811 0.7427 0.6324 0.0000 0.0000 0.0021 0.0062 0.0374 0.0811 0.0395 0.0457 0.7879 4 5 5 6 6 7 7 8 8 0.0274 6.20 3.980 0.3875 41.8
302.145
2320.55
18932.6
0.4537 0.1856 0.0023 0.0005 0.0113 0.0013 0.0441 0.0090 0.1027 0.0249 0.1782 0.0542 0.2398 0.1111 0.2262 0.2325 0.1613 0.3262 0.0341 0.2402 0.0000 0.0000 0.0017 0.0005 0.0047 0.0016 0.0231 0.0099 0.0540 0.0309 0.1005 0.0574 0.1816 0.1030 0.3028 0.2870 0.3314 0.5097 0.1740 0.3416 0.2290 0.2805 0.1980 0.1584 0.1530 0.1041 0.1140 0.0679 0.0770 0.0181 0.0260 0.0158 0.0230 0.0090 0.0060 0.0045 0.0029 0.0141 0.0417 0.0959 0.1617 0.2172 0.2159 0.1543 0.0962
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 461 123 image if available 3257 6809 514.7 105.53 61.25 124.20 368 433 474 500 525 551 579 608 638 0.0824 561 0.766 87.00 16.03 3 0.0620 202 0.0010 52.75 7.148 0.1825 276060.0
153000000
86800000000
50400000000000
0.4286 0.2196 0.0000 0.0000 0.0014 0.0000 0.0068 0.0000 0.0140 0.0013 0.0512 0.0198 0.0978 0.0406 0.0965 0.0227 0.1277 0.0373 0.6046 0.8782 0.0000 0.0000 0.0000 0.0000 0.0004 0.0000 0.0029 0.0013 0.0220 0.0197 0.0447 0.0384 0.0293 0.0184 0.0411 0.0288 0.8596 0.8934 0.0077 0.1333 0.0173 0.1333 0.0288 0.0667 0.0865 0.1333 0.1404 0.2667 0.1442 0.1333 0.1231 0.0000 0.1654 0.1333 0.2865 0.0000 0.0011 0.0023 0.0079 0.0186 0.0514 0.0814 0.0729 0.1040 0.6605 7 9 11 12 14 19 31 56 175 0.1883 7.43 3.201 0.7374 19174.6
10600000
7360000000
5780000000000
0.4921 0.1647 0.0338 0.0142 0.0549 0.0252 0.0717 0.0377 0.0928 0.0660 0.1392 0.0849 0.1814 0.1289 0.2363 0.1321 0.1097 0.1525 0.0802 0.3585 0.0034 0.0045 0.0048 0.0078 0.0034 0.0111 0.0109 0.0167 0.0212 0.0279 0.0519 0.0507 0.0355 0.0423 0.0444 0.0591 0.8245 0.7799 0.0000 0.0000 0.0008 0.0000 0.0016 0.0000 0.0073 0.0078 0.0334 0.0336 0.0465 0.0509 0.0302 0.0259 0.0522 0.0578 0.8280 0.8240 0.0008 0.0008 0.0046 0.0106 0.0236 0.0540 0.0274 0.0547 0.8237