High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 693 | | 1758 | 9747 | 194.5 | 65.03 | 7.39 | 2.56 | 126 | 140 | 153 | 164 | 173 | 189 | 216 | 254 | 297 | 0.0806 | 786 | 1.223 | 29.83 | 11.66 | 2 | 0.0438 | 77 | 0.0089 | 2.56 | 5.059 | 0.5219 | 42048.1 | 10100000 | 2640000000 | 742000000000 | 0.3576 | 0.2730 | 0.0013 | 0.0000 | 0.0053 | 0.0007 | 0.0093 | 0.0043 | 0.0200 | 0.0100 | 0.0787 | 0.0400 | 0.1267 | 0.0557 | 0.1067 | 0.0550 | 0.1440 | 0.0764 | 0.5080 | 0.7580 | 0.0008 | 0.0000 | 0.0034 | 0.0006 | 0.0050 | 0.0024 | 0.0101 | 0.0078 | 0.0378 | 0.0269 | 0.0512 | 0.0305 | 0.0419 | 0.0335 | 0.0680 | 0.0449 | 0.7819 | 0.8533 | 0.0023 | 0.0037 | 0.0000 | 0.0037 | 0.0000 | 0.0000 | 0.0090 | 0.0186 | 0.0498 | 0.0520 | 0.0611 | 0.0892 | 0.0452 | 0.0520 | 0.0656 | 0.0743 | 0.7670 | 0.7063 | 0.0000 | 0.0000 | 0.0030 | 0.0076 | 0.0318 | 0.0636 | 0.0394 | 0.0561 | 0.7985 | 4 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0172 | 8.20 | 4.461 | 0.3585 | 61.1 | 562.508 | 5723.84 | 64032.1 | 0.4837 | 0.1687 | 0.0143 | 0.0020 | 0.0491 | 0.0072 | 0.1154 | 0.0186 | 0.1968 | 0.0459 | 0.2244 | 0.0938 | 0.2015 | 0.1724 | 0.1356 | 0.2637 | 0.0542 | 0.2652 | 0.0087 | 0.1312 | 0.0012 | 0.0000 | 0.0093 | 0.0006 | 0.0270 | 0.0038 | 0.0627 | 0.0130 | 0.1007 | 0.0342 | 0.1357 | 0.0750 | 0.1749 | 0.1500 | 0.2022 | 0.2720 | 0.2862 | 0.4515 | 0.1173 | 0.1778 | 0.1454 | 0.1541 | 0.1396 | 0.1171 | 0.1150 | 0.1141 | 0.1015 | 0.0801 | 0.0904 | 0.0898 | 0.0869 | 0.0746 | 0.0800 | 0.0728 | 0.1238 | 0.1195 | 0.0077 | 0.0301 | 0.0649 | 0.1143 | 0.1463 | 0.1559 | 0.1546 | 0.1313 | 0.1950 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 506 | 842 | | 4164 | 7027 | 174.9 | 56.54 | 178.00 | 147.56 | 112 | 130 | 142 | 152 | 163 | 178 | 195 | 217 | 248 | 0.0992 | 697 | 1.133 | 87.73 | 29.97 | 1 | 0.0531 | 221 | 0.0010 | 60.00 | 7.142 | 0.1752 | 33770.8 | 7210000 | 1700000000 | 440000000000 | 0.4464 | 0.2087 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0141 | 0.0006 | 0.0522 | 0.0044 | 0.1370 | 0.0397 | 0.1936 | 0.0823 | 0.1921 | 0.0887 | 0.1775 | 0.1264 | 0.2301 | 0.6580 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0116 | 0.0021 | 0.0475 | 0.0234 | 0.0857 | 0.0412 | 0.0834 | 0.0368 | 0.1113 | 0.0577 | 0.6565 | 0.8388 | 0.0031 | 0.0022 | 0.0021 | 0.0153 | 0.0073 | 0.0131 | 0.0636 | 0.1160 | 0.1366 | 0.1751 | 0.1783 | 0.2079 | 0.1220 | 0.1072 | 0.1689 | 0.1379 | 0.3180 | 0.2254 | 0.0011 | 0.0006 | 0.0034 | 0.0311 | 0.0911 | 0.1324 | 0.1046 | 0.1414 | 0.4943 | 27 | 50 | 74 | 106 | 140 | 178 | 225 | 292 | 389 | 0.0022 | 67.53 | 7.034 | 0.2591 | 53457.0 | 21400000 | 10400000000 | 5770000000000 | 0.4709 | 0.1839 | 0.0246 | 0.0021 | 0.1054 | 0.0050 | 0.2141 | 0.0504 | 0.1742 | 0.0881 | 0.1708 | 0.1448 | 0.1351 | 0.1725 | 0.0799 | 0.1469 | 0.0654 | 0.1452 | 0.0306 | 0.2451 | 0.0003 | 0.0007 | 0.0014 | 0.0000 | 0.0041 | 0.0026 | 0.0151 | 0.0086 | 0.0704 | 0.0509 | 0.1194 | 0.0961 | 0.0898 | 0.0692 | 0.1292 | 0.1056 | 0.5703 | 0.6664 | 0.0022 | 0.0022 | 0.0035 | 0.0049 | 0.0101 | 0.0121 | 0.0321 | 0.0351 | 0.0981 | 0.1185 | 0.1438 | 0.1580 | 0.1130 | 0.0971 | 0.1328 | 0.1377 | 0.4644 | 0.4344 | 0.0004 | 0.0028 | 0.0042 | 0.0276 | 0.0850 | 0.1324 | 0.0967 | 0.1328 | 0.5181 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 232 | 638 | | 6254 | 5949 | 114.7 | 25.41 | 187.62 | 143.24 | 87 | 94 | 100 | 105 | 110 | 116 | 123 | 132 | 150 | 0.1308 | 778 | 0.961 | 106.23 | 31.32 | 1 | 0.0421 | 263 | 0.0034 | 14.14 | 6.046 | 0.2876 | 13792.0 | 1750000 | 233000000 | 32800000000 | 0.4648 | 0.1869 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0092 | 0.0003 | 0.0230 | 0.0024 | 0.0653 | 0.0177 | 0.1219 | 0.0491 | 0.1387 | 0.0346 | 0.1702 | 0.0694 | 0.4696 | 0.8265 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0003 | 0.0324 | 0.0105 | 0.0605 | 0.0277 | 0.0714 | 0.0137 | 0.0961 | 0.0290 | 0.7274 | 0.9189 | 0.0097 | 0.0198 | 0.0117 | 0.0074 | 0.0272 | 0.0272 | 0.0690 | 0.0743 | 0.1370 | 0.2030 | 0.1594 | 0.1807 | 0.1108 | 0.1436 | 0.1429 | 0.1337 | 0.3324 | 0.2104 | 0.0023 | 0.0109 | 0.0214 | 0.0436 | 0.1019 | 0.1320 | 0.1169 | 0.1421 | 0.4289 | 42 | 65 | 88 | 115 | 148 | 183 | 233 | 303 | 394 | 0.0021 | 69.90 | 6.913 | 0.2582 | 55713.5 | 21700000 | 10100000000 | 5300000000000 | 0.5779 | 0.0961 | 0.0346 | 0.0023 | 0.1508 | 0.0121 | 0.2315 | 0.0680 | 0.1585 | 0.1253 | 0.1537 | 0.1524 | 0.1162 | 0.1729 | 0.0836 | 0.1356 | 0.0500 | 0.1212 | 0.0211 | 0.2102 | 0.0017 | 0.0003 | 0.0017 | 0.0017 | 0.0069 | 0.0050 | 0.0247 | 0.0182 | 0.0897 | 0.0636 | 0.1357 | 0.1151 | 0.1103 | 0.0851 | 0.1454 | 0.1258 | 0.4838 | 0.5854 | 0.0016 | 0.0047 | 0.0064 | 0.0034 | 0.0112 | 0.0229 | 0.0508 | 0.0518 | 0.1086 | 0.1312 | 0.1825 | 0.1783 | 0.1215 | 0.1285 | 0.1429 | 0.1406 | 0.3745 | 0.3385 | 0.0004 | 0.0017 | 0.0120 | 0.0322 | 0.1043 | 0.1550 | 0.1245 | 0.1426 | 0.4272 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 919 | 384 | | 3864 | 10644 | 549.9 | 111.66 | 119.69 | 118.07 | 401 | 445 | 482 | 515 | 547 | 581 | 614 | 651 | 699 | 0.0750 | 798 | 1.029 | 90.48 | 35.85 | 1 | 0.0663 | 256 | 0.0007 | 70.72 | 7.491 | 0.1370 | 314839.0 | 187000000 | 115000000000 | 72500000000000 | 0.4423 | 0.2000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0000 | 0.0131 | 0.0027 | 0.0668 | 0.0158 | 0.1439 | 0.0363 | 0.1447 | 0.0328 | 0.1681 | 0.0507 | 0.4596 | 0.8617 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0051 | 0.0021 | 0.0277 | 0.0136 | 0.0621 | 0.0288 | 0.0535 | 0.0207 | 0.0701 | 0.0298 | 0.7804 | 0.9050 | 0.0029 | 0.0519 | 0.0114 | 0.0390 | 0.0157 | 0.0390 | 0.0672 | 0.1818 | 0.1502 | 0.2338 | 0.1788 | 0.1948 | 0.1288 | 0.1169 | 0.1431 | 0.0519 | 0.3019 | 0.0909 | 0.0000 | 0.0010 | 0.0037 | 0.0199 | 0.0659 | 0.1141 | 0.0795 | 0.1141 | 0.6018 | 11 | 15 | 23 | 44 | 81 | 122 | 165 | 219 | 293 | 0.0192 | 16.46 | 5.675 | 0.4317 | 28266.0 | 8580000 | 3000000000 | 1160000000000 | 0.4622 | 0.1810 | 0.0320 | 0.0021 | 0.1652 | 0.0111 | 0.2654 | 0.0848 | 0.1446 | 0.1330 | 0.1611 | 0.2072 | 0.1002 | 0.1734 | 0.0666 | 0.1199 | 0.0411 | 0.1273 | 0.0238 | 0.1413 | 0.0004 | 0.0004 | 0.0002 | 0.0004 | 0.0026 | 0.0020 | 0.0100 | 0.0065 | 0.0573 | 0.0464 | 0.0915 | 0.0770 | 0.0713 | 0.0525 | 0.1045 | 0.0919 | 0.6622 | 0.7230 | 0.0003 | 0.0006 | 0.0019 | 0.0016 | 0.0054 | 0.0048 | 0.0200 | 0.0279 | 0.0764 | 0.0901 | 0.1300 | 0.1487 | 0.0978 | 0.0983 | 0.1230 | 0.1376 | 0.5451 | 0.4903 | 0.0005 | 0.0016 | 0.0023 | 0.0137 | 0.0615 | 0.1121 | 0.0896 | 0.1246 | 0.5942 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 110 | 146 | | 3370 | 10890 | 147.0 | 47.54 | 205.95 | 210.52 | 96 | 109 | 120 | 130 | 141 | 152 | 166 | 184 | 210 | 0.0687 | 748 | 0.698 | 87.82 | 16.12 | 1 | 0.0591 | 199 | 0.0013 | 45.70 | 6.937 | 0.1972 | 23872.7 | 4240000 | 821000000 | 172000000000 | 0.4754 | 0.1834 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0213 | 0.0022 | 0.0640 | 0.0076 | 0.1469 | 0.0404 | 0.2133 | 0.0913 | 0.1633 | 0.0822 | 0.1664 | 0.1230 | 0.2176 | 0.6533 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0021 | 0.0003 | 0.0144 | 0.0026 | 0.0499 | 0.0204 | 0.0960 | 0.0459 | 0.0828 | 0.0328 | 0.1240 | 0.0548 | 0.6288 | 0.8431 | 0.0013 | 0.0000 | 0.0038 | 0.0233 | 0.0115 | 0.0465 | 0.0712 | 0.0930 | 0.1387 | 0.1964 | 0.2010 | 0.1783 | 0.1221 | 0.1163 | 0.1425 | 0.1370 | 0.3079 | 0.2093 | 0.0000 | 0.0026 | 0.0073 | 0.0389 | 0.0956 | 0.1404 | 0.1107 | 0.1325 | 0.4720 | 20 | 29 | 54 | 89 | 136 | 193 | 264 | 354 | 501 | 0.0118 | 65.86 | 6.461 | 0.3264 | 86732.2 | 51500000 | 38400000000 | 34300000000000 | 0.4942 | 0.1738 | 0.0577 | 0.0022 | 0.1982 | 0.0147 | 0.2589 | 0.0932 | 0.1590 | 0.1398 | 0.1250 | 0.1746 | 0.0895 | 0.1735 | 0.0643 | 0.1315 | 0.0348 | 0.1305 | 0.0126 | 0.1401 | 0.0006 | 0.0002 | 0.0021 | 0.0007 | 0.0027 | 0.0018 | 0.0144 | 0.0103 | 0.0681 | 0.0533 | 0.1264 | 0.0962 | 0.0930 | 0.0790 | 0.1328 | 0.1098 | 0.5599 | 0.6487 | 0.0006 | 0.0017 | 0.0011 | 0.0058 | 0.0108 | 0.0178 | 0.0354 | 0.0463 | 0.1058 | 0.1014 | 0.1580 | 0.1570 | 0.1044 | 0.1056 | 0.1298 | 0.1395 | 0.4541 | 0.4249 | 0.0000 | 0.0012 | 0.0063 | 0.0167 | 0.0951 | 0.1417 | 0.1103 | 0.1347 | 0.4942 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 972 | 177 | | 395 | 12546 | 117.2 | 19.48 | 22.21 | 93.56 | 93 | 98 | 104 | 109 | 113 | 121 | 128 | 137 | 146 | 0.0524 | 657 | 1.105 | 42.05 | 12.04 | 0 | 0.2380 | 94 | 0.0471 | 0.93 | 3.300 | 0.6696 | 14103.0 | 1740000 | 221000000 | 28700000000 | 0.3949 | 0.2407 | 0.0000 | 0.0000 | 0.0102 | 0.0000 | 0.0136 | 0.0000 | 0.0374 | 0.0127 | 0.0646 | 0.0433 | 0.1224 | 0.0738 | 0.1327 | 0.0585 | 0.1565 | 0.0916 | 0.4626 | 0.7201 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0085 | 0.0000 | 0.0254 | 0.0127 | 0.0366 | 0.0430 | 0.0732 | 0.0734 | 0.0704 | 0.0532 | 0.0789 | 0.0658 | 0.7042 | 0.7519 | 0.0000 | 0.0000 | 0.0164 | 1.0000 | 0.0492 | 0.0000 | 0.0820 | 0.0000 | 0.0984 | 0.0000 | 0.1639 | 0.0000 | 0.1148 | 0.0000 | 0.1967 | 0.0000 | 0.2787 | 0.0000 | 0.0055 | 0.0055 | 0.0000 | 0.0497 | 0.0552 | 0.0718 | 0.0939 | 0.0939 | 0.6243 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 14 | 0.1205 | 3.55 | 1.534 | 0.4274 | 9246.7 | 8900000 | 10500000000 | 13500000000000 | 0.4645 | 0.1926 | 0.0604 | 0.1758 | 0.1758 | 0.0687 | 0.2582 | 0.0929 | 0.3462 | 0.1414 | 0.1099 | 0.1980 | 0.0385 | 0.1737 | 0.0110 | 0.0747 | 0.0000 | 0.0485 | 0.0000 | 0.0263 | 0.0000 | 0.0672 | 0.0020 | 0.0227 | 0.0099 | 0.0180 | 0.0159 | 0.0164 | 0.0556 | 0.0469 | 0.0724 | 0.0618 | 0.0764 | 0.0641 | 0.1022 | 0.0821 | 0.6657 | 0.6208 | 0.0024 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0026 | 0.0182 | 0.0140 | 0.0654 | 0.0727 | 0.0956 | 0.0969 | 0.0690 | 0.0625 | 0.0920 | 0.0982 | 0.6550 | 0.6531 | 0.0000 | 0.0022 | 0.0065 | 0.0196 | 0.0577 | 0.0882 | 0.0719 | 0.0882 | 0.6656 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 526 | 612 | | 4592 | 11096 | 714.2 | 99.82 | 91.74 | 166.81 | 589 | 634 | 669 | 693 | 712 | 732 | 756 | 790 | 865 | 0.0617 | 685 | 1.192 | 82.49 | 32.31 | 1 | 0.0464 | 213 | 0.0012 | 39.16 | 7.036 | 0.2240 | 520098.0 | 386000000 | 291000000000 | 223000000000000 | 0.3926 | 0.2577 | 0.0013 | 0.0000 | 0.0016 | 0.0000 | 0.0024 | 0.0000 | 0.0078 | 0.0000 | 0.0202 | 0.0126 | 0.0427 | 0.0244 | 0.0333 | 0.0109 | 0.0462 | 0.0196 | 0.8444 | 0.9324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0000 | 0.0120 | 0.0126 | 0.0271 | 0.0244 | 0.0165 | 0.0109 | 0.0268 | 0.0196 | 0.9153 | 0.9324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0133 | 0.0000 | 0.0285 | 0.0000 | 0.0645 | 0.0000 | 0.1082 | 0.0000 | 0.1176 | 0.0000 | 0.1442 | 0.0000 | 0.5237 | 0.0000 | 0.0022 | 0.0027 | 0.0111 | 0.0200 | 0.0408 | 0.0616 | 0.0585 | 0.0789 | 0.7242 | 7 | 9 | 10 | 13 | 19 | 35 | 59 | 122 | 282 | 0.1396 | 15.62 | 3.866 | 0.6295 | 36238.5 | 22600000 | 17000000000 | 14400000000000 | 0.4303 | 0.1803 | 0.0541 | 0.0062 | 0.1723 | 0.0346 | 0.2804 | 0.0892 | 0.1486 | 0.1277 | 0.1216 | 0.1600 | 0.0912 | 0.1738 | 0.0456 | 0.1138 | 0.0372 | 0.1200 | 0.0490 | 0.1746 | 0.0007 | 0.0006 | 0.0014 | 0.0026 | 0.0061 | 0.0038 | 0.0208 | 0.0191 | 0.0546 | 0.0430 | 0.0869 | 0.0774 | 0.0440 | 0.0543 | 0.0617 | 0.0676 | 0.7238 | 0.7317 | 0.0009 | 0.0009 | 0.0021 | 0.0023 | 0.0081 | 0.0069 | 0.0214 | 0.0236 | 0.0585 | 0.0573 | 0.0880 | 0.0906 | 0.0440 | 0.0495 | 0.0679 | 0.0703 | 0.7091 | 0.6986 | 0.0008 | 0.0015 | 0.0073 | 0.0191 | 0.0546 | 0.0863 | 0.0454 | 0.0569 | 0.7281 | ||
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 609 | 251 | | 8474 | 32235 | 492.3 | 132.68 | 164.80 | 304.29 | 304 | 403 | 447 | 478 | 505 | 531 | 562 | 596 | 642 | 0.0423 | 1362 | 0.553 | 103.04 | 22.02 | 6 | 0.0340 | 288 | 0.0004 | 114.84 | 8.011 | 0.1304 | 259967.0 | 144000000 | 83000000000 | 49400000000000 | 0.3722 | 0.2591 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0037 | 0.0003 | 0.0143 | 0.0023 | 0.0499 | 0.0166 | 0.1100 | 0.0376 | 0.1112 | 0.0351 | 0.1452 | 0.0452 | 0.5648 | 0.8630 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0001 | 0.0025 | 0.0009 | 0.0146 | 0.0117 | 0.0325 | 0.0201 | 0.0307 | 0.0127 | 0.0470 | 0.0181 | 0.8723 | 0.9363 | 0.0022 | 0.0048 | 0.0077 | 0.0143 | 0.0132 | 0.0286 | 0.0548 | 0.0835 | 0.1064 | 0.2124 | 0.1656 | 0.1742 | 0.1162 | 0.1074 | 0.1436 | 0.1480 | 0.3904 | 0.2267 | 0.0004 | 0.0024 | 0.0034 | 0.0209 | 0.0482 | 0.0869 | 0.0897 | 0.1054 | 0.6428 | 11 | 14 | 16 | 19 | 25 | 41 | 97 | 243 | 543 | 0.1744 | 25.68 | 4.127 | 0.6433 | 119746.0 | 132000000 | 179000000000 | 274000000000000 | 0.3012 | 0.3397 | 0.0899 | 0.0040 | 0.2395 | 0.0218 | 0.2653 | 0.1374 | 0.1444 | 0.1732 | 0.1091 | 0.1910 | 0.0818 | 0.1739 | 0.0413 | 0.1102 | 0.0177 | 0.0848 | 0.0111 | 0.1039 | 0.0005 | 0.0004 | 0.0016 | 0.0005 | 0.0018 | 0.0022 | 0.0158 | 0.0127 | 0.0501 | 0.0477 | 0.0704 | 0.0633 | 0.0461 | 0.0432 | 0.0696 | 0.0655 | 0.7443 | 0.7646 | 0.0003 | 0.0003 | 0.0003 | 0.0026 | 0.0043 | 0.0048 | 0.0182 | 0.0201 | 0.0595 | 0.0574 | 0.0778 | 0.0868 | 0.0553 | 0.0575 | 0.0768 | 0.0805 | 0.7076 | 0.6901 | 0.0004 | 0.0001 | 0.0031 | 0.0149 | 0.0534 | 0.0785 | 0.0435 | 0.0762 | 0.7299 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 141 | 279 | | 6550 | 28560 | 325.2 | 76.94 | 118.00 | 205.38 | 229 | 259 | 281 | 299 | 318 | 339 | 361 | 391 | 431 | 0.0380 | 1086 | 1.019 | 88.10 | 26.68 | 3 | 0.0337 | 221 | 0.0007 | 63.80 | 7.487 | 0.1467 | 111704.0 | 40400000 | 15300000000 | 6070000000000 | 0.4422 | 0.2121 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0067 | 0.0012 | 0.0248 | 0.0030 | 0.0781 | 0.0206 | 0.1554 | 0.0495 | 0.1682 | 0.0513 | 0.1992 | 0.0834 | 0.3659 | 0.7909 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0003 | 0.0069 | 0.0006 | 0.0339 | 0.0127 | 0.0714 | 0.0286 | 0.0678 | 0.0219 | 0.0992 | 0.0413 | 0.7200 | 0.8945 | 0.0053 | 0.0096 | 0.0114 | 0.0288 | 0.0220 | 0.0745 | 0.0676 | 0.0962 | 0.1277 | 0.1923 | 0.1634 | 0.1635 | 0.1087 | 0.1130 | 0.1664 | 0.1394 | 0.3275 | 0.1827 | 0.0010 | 0.0043 | 0.0085 | 0.0299 | 0.0768 | 0.1404 | 0.1063 | 0.1358 | 0.4970 | 7 | 9 | 10 | 12 | 16 | 29 | 83 | 200 | 398 | 0.1579 | 24.15 | 4.168 | 0.5959 | 56105.0 | 38900000 | 32800000000 | 31500000000000 | 0.4719 | 0.1982 | 0.0778 | 0.0031 | 0.2645 | 0.0291 | 0.3497 | 0.1507 | 0.1482 | 0.1884 | 0.0819 | 0.2342 | 0.0426 | 0.1740 | 0.0180 | 0.0983 | 0.0098 | 0.0746 | 0.0074 | 0.0478 | 0.0000 | 0.0001 | 0.0004 | 0.0002 | 0.0004 | 0.0003 | 0.0067 | 0.0067 | 0.0467 | 0.0397 | 0.0880 | 0.0720 | 0.0536 | 0.0512 | 0.0899 | 0.0787 | 0.7143 | 0.7511 | 0.0001 | 0.0003 | 0.0004 | 0.0012 | 0.0016 | 0.0016 | 0.0092 | 0.0145 | 0.0557 | 0.0597 | 0.1096 | 0.1123 | 0.0663 | 0.0794 | 0.1060 | 0.1115 | 0.6510 | 0.6194 | 0.0000 | 0.0001 | 0.0019 | 0.0094 | 0.0525 | 0.0917 | 0.0654 | 0.0947 | 0.6842 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 701 | 708 | | 3960 | 7704 | 112.0 | 31.81 | 223.51 | 163.62 | 75 | 85 | 93 | 101 | 108 | 116 | 126 | 138 | 157 | 0.0803 | 619 | 0.927 | 110.80 | 33.29 | 1 | 0.0717 | 284 | 0.0027 | 16.60 | 6.248 | 0.2945 | 13565.0 | 1760000 | 244000000 | 35800000000 | 0.4753 | 0.1844 | 0.0014 | 0.0003 | 0.0024 | 0.0003 | 0.0125 | 0.0015 | 0.0313 | 0.0063 | 0.1020 | 0.0328 | 0.1607 | 0.0671 | 0.1526 | 0.0632 | 0.1877 | 0.0933 | 0.3494 | 0.7353 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0027 | 0.0008 | 0.0115 | 0.0032 | 0.0395 | 0.0171 | 0.0691 | 0.0338 | 0.0634 | 0.0261 | 0.0874 | 0.0389 | 0.7258 | 0.8798 | 0.0034 | 0.0025 | 0.0079 | 0.0101 | 0.0259 | 0.0226 | 0.0462 | 0.0955 | 0.1082 | 0.1583 | 0.1556 | 0.1935 | 0.1071 | 0.1332 | 0.1545 | 0.1734 | 0.3912 | 0.2111 | 0.0017 | 0.0022 | 0.0089 | 0.0279 | 0.0674 | 0.1070 | 0.0903 | 0.1260 | 0.5686 | 33 | 70 | 113 | 156 | 195 | 237 | 287 | 353 | 455 | 0.0025 | 36.71 | 6.898 | 0.2678 | 76724.5 | 33200000 | 16700000000 | 9360000000000 | 0.5297 | 0.1425 | 0.0044 | 0.0007 | 0.0481 | 0.0046 | 0.1665 | 0.0118 | 0.1506 | 0.0358 | 0.1715 | 0.1340 | 0.1696 | 0.1741 | 0.1247 | 0.1485 | 0.0873 | 0.1656 | 0.0772 | 0.3249 | 0.0002 | 0.0002 | 0.0022 | 0.0012 | 0.0038 | 0.0024 | 0.0134 | 0.0064 | 0.0475 | 0.0395 | 0.0913 | 0.0621 | 0.0726 | 0.0627 | 0.1012 | 0.0881 | 0.6677 | 0.7374 | 0.0019 | 0.0015 | 0.0039 | 0.0005 | 0.0085 | 0.0071 | 0.0324 | 0.0341 | 0.0772 | 0.0896 | 0.1127 | 0.1197 | 0.0888 | 0.1064 | 0.1011 | 0.1253 | 0.5735 | 0.5158 | 0.0003 | 0.0021 | 0.0063 | 0.0174 | 0.0683 | 0.1061 | 0.0920 | 0.1102 | 0.5974 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 425 | 828 | | 9686 | 14128 | 100.3 | 24.59 | 205.89 | 202.72 | 72 | 79 | 85 | 91 | 97 | 103 | 110 | 120 | 135 | 0.0773 | 1092 | 0.773 | 63.03 | 19.85 | 4 | 0.0184 | 178 | 0.0016 | 27.28 | 6.760 | 0.2225 | 10667.4 | 1200000 | 143000000 | 18000000000 | 0.4311 | 0.2206 | 0.0007 | 0.0000 | 0.0025 | 0.0002 | 0.0089 | 0.0003 | 0.0289 | 0.0048 | 0.0826 | 0.0210 | 0.1495 | 0.0494 | 0.1653 | 0.0539 | 0.1882 | 0.0764 | 0.3734 | 0.7940 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0043 | 0.0000 | 0.0130 | 0.0021 | 0.0319 | 0.0109 | 0.0542 | 0.0231 | 0.0628 | 0.0163 | 0.0885 | 0.0251 | 0.7438 | 0.9226 | 0.0040 | 0.0078 | 0.0106 | 0.0142 | 0.0227 | 0.0492 | 0.0721 | 0.1410 | 0.1245 | 0.1643 | 0.1668 | 0.2018 | 0.1285 | 0.1294 | 0.1346 | 0.1345 | 0.3362 | 0.1578 | 0.0028 | 0.0044 | 0.0131 | 0.0331 | 0.0776 | 0.1130 | 0.1075 | 0.1367 | 0.5119 | 19 | 33 | 57 | 89 | 132 | 192 | 271 | 367 | 509 | 0.0106 | 35.88 | 6.248 | 0.3841 | 83484.1 | 45100000 | 28900000000 | 21200000000000 | 0.5547 | 0.1227 | 0.0456 | 0.0027 | 0.1805 | 0.0154 | 0.2495 | 0.1234 | 0.1651 | 0.1270 | 0.1294 | 0.1710 | 0.1041 | 0.1743 | 0.0548 | 0.1294 | 0.0370 | 0.1093 | 0.0339 | 0.1475 | 0.0005 | 0.0004 | 0.0013 | 0.0010 | 0.0037 | 0.0030 | 0.0122 | 0.0118 | 0.0659 | 0.0511 | 0.1064 | 0.0942 | 0.0799 | 0.0639 | 0.1109 | 0.0947 | 0.6192 | 0.6799 | 0.0004 | 0.0013 | 0.0022 | 0.0030 | 0.0061 | 0.0106 | 0.0230 | 0.0300 | 0.0848 | 0.0881 | 0.1339 | 0.1427 | 0.0916 | 0.1017 | 0.1258 | 0.1334 | 0.5322 | 0.4892 | 0.0002 | 0.0030 | 0.0037 | 0.0199 | 0.0732 | 0.1163 | 0.0904 | 0.1209 | 0.5723 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 607 | 650 | | 808 | 9723 | 822.7 | 285.42 | 10.47 | 10.85 | 493 | 549 | 610 | 675 | 765 | 856 | 972 | 1125 | 1261 | 0.0725 | 705 | 0.565 | 32.65 | 5.00 | 1 | 0.1114 | 90 | 0.0018 | 33.14 | 6.417 | 0.1590 | 758238.0 | 769000000 | 841000000000 | 970000000000000 | 0.3548 | 0.2711 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0038 | 0.0017 | 0.1057 | 0.0517 | 0.2453 | 0.1138 | 0.1057 | 0.0552 | 0.1811 | 0.0845 | 0.3585 | 0.6931 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0014 | 0.0400 | 0.0332 | 0.0700 | 0.0622 | 0.0280 | 0.0249 | 0.0600 | 0.0443 | 0.8000 | 0.8340 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0681 | 0.0839 | 0.1021 | 0.1259 | 0.0340 | 0.0420 | 0.0681 | 0.0909 | 0.7277 | 0.6504 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0538 | 0.0595 | 0.0482 | 0.0680 | 0.7620 | 5 | 6 | 6 | 7 | 8 | 8 | 9 | 11 | 17 | 0.1294 | 0.43 | 1.360 | 0.4878 | 227.2 | 11518.1 | 951002 | 99400000 | 0.4627 | 0.1724 | 0.0445 | 0.0009 | 0.1116 | 0.0040 | 0.1533 | 0.0184 | 0.1904 | 0.0460 | 0.1793 | 0.1011 | 0.1539 | 0.1744 | 0.0974 | 0.2117 | 0.0526 | 0.2479 | 0.0170 | 0.1955 | 0.0262 | 0.0002 | 0.0614 | 0.0026 | 0.0785 | 0.0118 | 0.0849 | 0.0295 | 0.0861 | 0.0688 | 0.0922 | 0.1203 | 0.0968 | 0.1483 | 0.1240 | 0.1897 | 0.3498 | 0.4287 | 0.0345 | 0.0237 | 0.0367 | 0.0266 | 0.0434 | 0.0180 | 0.0579 | 0.0633 | 0.0880 | 0.0957 | 0.1030 | 0.1165 | 0.0935 | 0.1043 | 0.1253 | 0.1288 | 0.4176 | 0.4230 | 0.0560 | 0.0567 | 0.0599 | 0.0685 | 0.0868 | 0.0890 | 0.1015 | 0.1209 | 0.3606 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1163 | 489 | | 321 | 5383 | 116.6 | 17.58 | 10.59 | 16.86 | 93 | 99 | 105 | 110 | 115 | 122 | 128 | 133 | 140 | 0.0832 | 448 | 1.174 | 34.48 | 13.89 | 3 | 0.2897 | 93 | 0.0412 | 1.34 | 3.375 | 0.6192 | 13896.5 | 1690000 | 210000000 | 26600000000 | 0.3932 | 0.2232 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0000 | 0.0388 | 0.0156 | 0.0930 | 0.0498 | 0.1395 | 0.1090 | 0.1395 | 0.0592 | 0.1938 | 0.0935 | 0.3837 | 0.6729 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0243 | 0.0156 | 0.0590 | 0.0498 | 0.1007 | 0.1090 | 0.0833 | 0.0592 | 0.1111 | 0.0935 | 0.6146 | 0.6729 | 0.0333 | 0.0000 | 0.0667 | 0.0000 | 0.0333 | 0.0000 | 0.1667 | 0.0000 | 0.2667 | 0.0000 | 0.2000 | 0.0000 | 0.1000 | 0.0000 | 0.1000 | 0.0000 | 0.0333 | 0.0000 | 0.0000 | 0.0000 | 0.0258 | 0.0516 | 0.0839 | 0.1290 | 0.0710 | 0.1032 | 0.5355 | 3 | 5 | 6 | 6 | 7 | 8 | 9 | 10 | 13 | 0.1037 | 0.50 | 1.327 | 0.4010 | 396.2 | 39837.1 | 5690000 | 976000000 | 0.5867 | 0.1158 | 0.1081 | 0.0234 | 0.1521 | 0.0646 | 0.1822 | 0.1055 | 0.1683 | 0.1248 | 0.1992 | 0.1564 | 0.1228 | 0.1745 | 0.0533 | 0.1681 | 0.0139 | 0.1293 | 0.0000 | 0.0533 | 0.0717 | 0.0199 | 0.1019 | 0.0545 | 0.1150 | 0.0857 | 0.0980 | 0.0980 | 0.1194 | 0.1193 | 0.1073 | 0.1330 | 0.0772 | 0.1375 | 0.0728 | 0.1248 | 0.2366 | 0.2273 | 0.0433 | 0.0158 | 0.0226 | 0.0204 | 0.0377 | 0.0226 | 0.0377 | 0.0385 | 0.0734 | 0.0973 | 0.1092 | 0.1154 | 0.0923 | 0.0905 | 0.1224 | 0.1222 | 0.4614 | 0.4774 | 0.1188 | 0.1103 | 0.0827 | 0.0562 | 0.0615 | 0.0679 | 0.0679 | 0.0933 | 0.3415 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1101 | 742 | | 4651 | 3841 | 130.8 | 24.62 | 205.76 | 139.04 | 103 | 111 | 116 | 122 | 128 | 133 | 140 | 148 | 161 | 0.1854 | 712 | 1.111 | 92.85 | 30.41 | 1 | 0.0495 | 230 | 0.0036 | 13.07 | 5.941 | 0.2993 | 17710.9 | 2490000 | 365000000 | 56000000000 | 0.4257 | 0.2249 | 0.0014 | 0.0000 | 0.0040 | 0.0000 | 0.0071 | 0.0000 | 0.0190 | 0.0025 | 0.0451 | 0.0167 | 0.0984 | 0.0362 | 0.1083 | 0.0292 | 0.1549 | 0.0442 | 0.5618 | 0.8712 | 0.0012 | 0.0000 | 0.0029 | 0.0000 | 0.0054 | 0.0000 | 0.0103 | 0.0017 | 0.0254 | 0.0129 | 0.0548 | 0.0241 | 0.0523 | 0.0146 | 0.0807 | 0.0226 | 0.7669 | 0.9241 | 0.0071 | 0.0059 | 0.0196 | 0.0294 | 0.0445 | 0.0471 | 0.0943 | 0.0824 | 0.1423 | 0.1765 | 0.1637 | 0.2176 | 0.1121 | 0.0706 | 0.1174 | 0.1647 | 0.2989 | 0.2059 | 0.0044 | 0.0083 | 0.0151 | 0.0432 | 0.0763 | 0.1122 | 0.1102 | 0.1336 | 0.4968 | 59 | 93 | 118 | 141 | 168 | 200 | 248 | 312 | 412 | 0.0015 | 56.43 | 6.903 | 0.2245 | 61663.9 | 23700000 | 10900000000 | 5660000000000 | 0.4849 | 0.1602 | 0.0169 | 0.0036 | 0.0784 | 0.0118 | 0.1858 | 0.0391 | 0.1701 | 0.0751 | 0.1725 | 0.1438 | 0.1556 | 0.1746 | 0.0941 | 0.1473 | 0.0760 | 0.1444 | 0.0507 | 0.2604 | 0.0020 | 0.0019 | 0.0040 | 0.0035 | 0.0106 | 0.0089 | 0.0323 | 0.0216 | 0.0751 | 0.0589 | 0.1280 | 0.0971 | 0.1154 | 0.0890 | 0.1260 | 0.1125 | 0.5066 | 0.6067 | 0.0017 | 0.0044 | 0.0121 | 0.0077 | 0.0113 | 0.0221 | 0.0459 | 0.0464 | 0.1013 | 0.1380 | 0.1636 | 0.1435 | 0.1022 | 0.1280 | 0.1411 | 0.1523 | 0.4208 | 0.3576 | 0.0020 | 0.0101 | 0.0181 | 0.0322 | 0.0938 | 0.1434 | 0.1139 | 0.1273 | 0.4591 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 279 | 429 | | 995 | 12586 | 70.7 | 14.90 | 155.58 | 186.93 | 55 | 59 | 63 | 66 | 69 | 72 | 76 | 81 | 90 | 0.0678 | 853 | 0.399 | 137.53 | 31.00 | 1 | 0.5668 | 564 | 0.0090 | 7.28 | 5.031 | 0.3913 | 5218.8 | 403150 | 32700000 | 2780000000 | 0.5290 | 0.1303 | 0.0014 | 0.0000 | 0.0041 | 0.0000 | 0.0218 | 0.0032 | 0.0476 | 0.0139 | 0.1252 | 0.0586 | 0.1823 | 0.1471 | 0.1469 | 0.0768 | 0.1524 | 0.1333 | 0.3184 | 0.5672 | 0.0012 | 0.0000 | 0.0012 | 0.0000 | 0.0046 | 0.0020 | 0.0207 | 0.0061 | 0.0794 | 0.0499 | 0.1427 | 0.1314 | 0.0863 | 0.0540 | 0.1116 | 0.0967 | 0.5524 | 0.6599 | 0.0149 | 0.0455 | 0.0149 | 0.0000 | 0.0522 | 0.1136 | 0.1343 | 0.1136 | 0.2015 | 0.2955 | 0.2015 | 0.2045 | 0.1119 | 0.0227 | 0.1269 | 0.1818 | 0.1418 | 0.0227 | 0.0068 | 0.0158 | 0.0158 | 0.0813 | 0.1512 | 0.1558 | 0.1129 | 0.1490 | 0.3115 | 16 | 20 | 30 | 53 | 84 | 116 | 167 | 264 | 418 | 0.0235 | 46.09 | 5.759 | 0.4355 | 59144.7 | 33000000 | 22700000000 | 17700000000000 | 0.5490 | 0.1235 | 0.0353 | 0.0025 | 0.1470 | 0.0151 | 0.2292 | 0.0792 | 0.1425 | 0.1235 | 0.1447 | 0.1704 | 0.1190 | 0.1746 | 0.0816 | 0.1179 | 0.0654 | 0.1193 | 0.0353 | 0.1975 | 0.0004 | 0.0007 | 0.0004 | 0.0019 | 0.0042 | 0.0029 | 0.0129 | 0.0102 | 0.0601 | 0.0507 | 0.1106 | 0.0865 | 0.0811 | 0.0676 | 0.1162 | 0.1025 | 0.6141 | 0.6771 | 0.0009 | 0.0010 | 0.0023 | 0.0017 | 0.0032 | 0.0023 | 0.0227 | 0.0252 | 0.0827 | 0.1026 | 0.1474 | 0.1437 | 0.0903 | 0.1010 | 0.1282 | 0.1400 | 0.5223 | 0.4826 | 0.0002 | 0.0015 | 0.0037 | 0.0187 | 0.0791 | 0.1231 | 0.0843 | 0.1271 | 0.5622 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 373 | 297 | | 8100 | 26881 | 413.8 | 80.21 | 134.66 | 112.18 | 311 | 343 | 368 | 389 | 410 | 432 | 457 | 483 | 520 | 0.0428 | 1150 | 1.063 | 121.84 | 35.38 | 1 | 0.0363 | 294 | 0.0012 | 29.87 | 6.930 | 0.2112 | 177657.0 | 78900000 | 36200000000 | 17100000000000 | 0.4441 | 0.2061 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0031 | 0.0001 | 0.0127 | 0.0006 | 0.0529 | 0.0119 | 0.1206 | 0.0278 | 0.1395 | 0.0227 | 0.1558 | 0.0414 | 0.5151 | 0.8954 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0038 | 0.0005 | 0.0215 | 0.0096 | 0.0486 | 0.0211 | 0.0558 | 0.0122 | 0.0700 | 0.0216 | 0.7987 | 0.9350 | 0.0038 | 0.0471 | 0.0045 | 0.0059 | 0.0257 | 0.0941 | 0.0863 | 0.1588 | 0.1529 | 0.1412 | 0.2044 | 0.2118 | 0.1317 | 0.0647 | 0.1363 | 0.0706 | 0.2544 | 0.2059 | 0.0005 | 0.0013 | 0.0066 | 0.0247 | 0.0683 | 0.1268 | 0.1056 | 0.1298 | 0.5363 | 27 | 46 | 66 | 85 | 107 | 130 | 159 | 200 | 272 | 0.0091 | 10.68 | 5.490 | 0.4380 | 30717.4 | 10300000 | 4530000000 | 2410000000000 | 0.4651 | 0.1879 | 0.0107 | 0.0010 | 0.0569 | 0.0033 | 0.1502 | 0.0207 | 0.1620 | 0.0586 | 0.1808 | 0.1345 | 0.1705 | 0.1748 | 0.1171 | 0.1516 | 0.0871 | 0.1645 | 0.0646 | 0.2909 | 0.0008 | 0.0005 | 0.0020 | 0.0009 | 0.0061 | 0.0038 | 0.0179 | 0.0117 | 0.0589 | 0.0446 | 0.1034 | 0.0774 | 0.0837 | 0.0680 | 0.1176 | 0.1006 | 0.6097 | 0.6925 | 0.0016 | 0.0022 | 0.0055 | 0.0050 | 0.0095 | 0.0162 | 0.0356 | 0.0429 | 0.0832 | 0.1003 | 0.1356 | 0.1457 | 0.1111 | 0.1195 | 0.1349 | 0.1425 | 0.4830 | 0.4257 | 0.0007 | 0.0045 | 0.0076 | 0.0250 | 0.0755 | 0.1170 | 0.0983 | 0.1280 | 0.5435 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 883 | 333 | | 6557 | 23757 | 237.9 | 49.19 | 167.48 | 247.49 | 178 | 194 | 208 | 219 | 232 | 246 | 261 | 279 | 306 | 0.0424 | 1007 | 0.712 | 125.45 | 28.02 | 1 | 0.0450 | 295 | 0.0009 | 51.46 | 7.234 | 0.1754 | 59019.4 | 15300000 | 4100000000 | 1150000000000 | 0.4457 | 0.2085 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0056 | 0.0002 | 0.0195 | 0.0010 | 0.0674 | 0.0163 | 0.1393 | 0.0371 | 0.1433 | 0.0322 | 0.1613 | 0.0570 | 0.4629 | 0.8563 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0061 | 0.0002 | 0.0308 | 0.0103 | 0.0701 | 0.0231 | 0.0660 | 0.0135 | 0.0840 | 0.0266 | 0.7414 | 0.9264 | 0.0026 | 0.0174 | 0.0141 | 0.0208 | 0.0132 | 0.0590 | 0.0695 | 0.1042 | 0.1240 | 0.1979 | 0.1803 | 0.1736 | 0.1152 | 0.1285 | 0.1495 | 0.1250 | 0.3316 | 0.1736 | 0.0013 | 0.0020 | 0.0073 | 0.0295 | 0.0809 | 0.1283 | 0.1037 | 0.1332 | 0.5138 | 10 | 11 | 13 | 15 | 22 | 70 | 185 | 328 | 546 | 0.0818 | 47.97 | 5.085 | 0.5273 | 89297.6 | 63700000 | 53300000000 | 49900000000000 | 0.5956 | 0.0948 | 0.0674 | 0.0040 | 0.2566 | 0.0182 | 0.3191 | 0.1656 | 0.1332 | 0.1895 | 0.1118 | 0.2077 | 0.0683 | 0.1749 | 0.0238 | 0.1020 | 0.0132 | 0.0814 | 0.0066 | 0.0567 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0008 | 0.0079 | 0.0064 | 0.0468 | 0.0389 | 0.0815 | 0.0785 | 0.0589 | 0.0508 | 0.0832 | 0.0748 | 0.7206 | 0.7498 | 0.0003 | 0.0000 | 0.0012 | 0.0024 | 0.0026 | 0.0046 | 0.0111 | 0.0124 | 0.0508 | 0.0535 | 0.0996 | 0.1030 | 0.0647 | 0.0701 | 0.0889 | 0.0964 | 0.6808 | 0.6577 | 0.0001 | 0.0012 | 0.0017 | 0.0109 | 0.0482 | 0.0875 | 0.0665 | 0.0853 | 0.6985 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 537 | 652 | | 760 | 4733 | 183.3 | 48.14 | 141.14 | 250.71 | 130 | 142 | 153 | 163 | 173 | 188 | 202 | 222 | 250 | 0.1054 | 499 | 0.979 | 146.17 | 42.01 | 2 | 0.4618 | 351 | 0.0030 | 36.55 | 6.002 | 0.2222 | 35909.5 | 7530000 | 1680000000 | 400000000000 | 0.4861 | 0.1592 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0652 | 0.0044 | 0.0966 | 0.0175 | 0.1473 | 0.0773 | 0.1546 | 0.0962 | 0.1812 | 0.0845 | 0.1594 | 0.0962 | 0.1860 | 0.6239 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0297 | 0.0054 | 0.0822 | 0.0549 | 0.1154 | 0.0776 | 0.1136 | 0.0415 | 0.1416 | 0.0776 | 0.5105 | 0.7430 | 0.0000 | 0.0000 | 0.0063 | 0.0000 | 0.0253 | 0.0328 | 0.0823 | 0.2131 | 0.2595 | 0.2295 | 0.1329 | 0.2131 | 0.1139 | 0.0984 | 0.1835 | 0.1311 | 0.1962 | 0.0820 | 0.0000 | 0.0000 | 0.0150 | 0.0300 | 0.1502 | 0.1922 | 0.0991 | 0.1381 | 0.3754 | 7 | 8 | 10 | 12 | 18 | 39 | 88 | 210 | 496 | 0.1437 | 25.58 | 4.029 | 0.5929 | 82762.0 | 66600000 | 60800000000 | 59600000000000 | 0.6762 | 0.0517 | 0.0645 | 0.0022 | 0.2719 | 0.0410 | 0.3548 | 0.1339 | 0.1475 | 0.2009 | 0.0876 | 0.2203 | 0.0553 | 0.1749 | 0.0138 | 0.1058 | 0.0046 | 0.0756 | 0.0000 | 0.0454 | 0.0008 | 0.0000 | 0.0000 | 0.0007 | 0.0008 | 0.0007 | 0.0094 | 0.0131 | 0.0602 | 0.0518 | 0.1063 | 0.0801 | 0.0493 | 0.0608 | 0.1009 | 0.0849 | 0.6724 | 0.7079 | 0.0000 | 0.0000 | 0.0019 | 0.0020 | 0.0028 | 0.0020 | 0.0104 | 0.0132 | 0.0669 | 0.0731 | 0.1121 | 0.1015 | 0.0574 | 0.0701 | 0.0989 | 0.1036 | 0.6497 | 0.6345 | 0.0000 | 0.0000 | 0.0034 | 0.0086 | 0.0738 | 0.0935 | 0.0626 | 0.0995 | 0.6587 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 309 | 287 | | 6693 | 13038 | 535.8 | 126.02 | 220.15 | 377.39 | 361 | 403 | 454 | 495 | 535 | 584 | 628 | 661 | 696 | 0.0639 | 833 | 0.910 | 75.03 | 22.56 | 1 | 0.0288 | 193 | 0.0006 | 30.06 | 7.569 | 0.2086 | 303013.0 | 179000000 | 110000000000 | 69800000000000 | 0.3886 | 0.2484 | 0.0015 | 0.0000 | 0.0045 | 0.0003 | 0.0063 | 0.0009 | 0.0218 | 0.0046 | 0.0499 | 0.0146 | 0.0646 | 0.0195 | 0.0738 | 0.0255 | 0.0999 | 0.0304 | 0.6777 | 0.9041 | 0.0002 | 0.0000 | 0.0006 | 0.0002 | 0.0000 | 0.0006 | 0.0040 | 0.0031 | 0.0151 | 0.0121 | 0.0173 | 0.0144 | 0.0213 | 0.0153 | 0.0279 | 0.0185 | 0.9136 | 0.9358 | 0.0000 | 0.0057 | 0.0066 | 0.0230 | 0.0119 | 0.0575 | 0.0328 | 0.0862 | 0.0519 | 0.1552 | 0.0781 | 0.1092 | 0.0972 | 0.1322 | 0.1151 | 0.1379 | 0.6064 | 0.2931 | 0.0003 | 0.0012 | 0.0018 | 0.0075 | 0.0221 | 0.0392 | 0.0374 | 0.0502 | 0.8404 | 9 | 11 | 13 | 16 | 29 | 82 | 190 | 352 | 702 | 0.1372 | 64.08 | 4.831 | 0.5651 | 190878.0 | 238000000 | 347000000000 | 556000000000000 | 0.2850 | 0.3373 | 0.0407 | 0.0012 | 0.1423 | 0.0098 | 0.1842 | 0.0952 | 0.1160 | 0.1173 | 0.1651 | 0.1419 | 0.1471 | 0.1751 | 0.0969 | 0.1204 | 0.0682 | 0.1106 | 0.0395 | 0.2285 | 0.0000 | 0.0000 | 0.0010 | 0.0002 | 0.0030 | 0.0007 | 0.0114 | 0.0099 | 0.0445 | 0.0399 | 0.0736 | 0.0527 | 0.0521 | 0.0432 | 0.0692 | 0.0647 | 0.7453 | 0.7886 | 0.0012 | 0.0003 | 0.0000 | 0.0010 | 0.0028 | 0.0059 | 0.0177 | 0.0200 | 0.0570 | 0.0596 | 0.0906 | 0.0950 | 0.0548 | 0.0665 | 0.0878 | 0.0871 | 0.6880 | 0.6646 | 0.0006 | 0.0008 | 0.0019 | 0.0171 | 0.0521 | 0.0803 | 0.0576 | 0.0745 | 0.7151 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 454 | 777 | | 7409 | 17484 | 322.3 | 67.54 | 205.37 | 234.69 | 243 | 264 | 279 | 296 | 313 | 331 | 353 | 381 | 419 | 0.0565 | 988 | 1.214 | 100.09 | 46.32 | 1 | 0.0378 | 280 | 0.0005 | 88.54 | 7.749 | 0.1264 | 108444.0 | 38100000 | 13900000000 | 5270000000000 | 0.4118 | 0.2358 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0027 | 0.0000 | 0.0126 | 0.0013 | 0.0653 | 0.0133 | 0.1407 | 0.0324 | 0.1465 | 0.0319 | 0.1766 | 0.0542 | 0.4551 | 0.8669 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0040 | 0.0001 | 0.0306 | 0.0082 | 0.0657 | 0.0178 | 0.0679 | 0.0118 | 0.0977 | 0.0245 | 0.7329 | 0.9376 | 0.0029 | 0.0057 | 0.0029 | 0.0172 | 0.0155 | 0.0602 | 0.0472 | 0.0888 | 0.1282 | 0.1977 | 0.1643 | 0.1748 | 0.1157 | 0.1175 | 0.1400 | 0.1547 | 0.3832 | 0.1834 | 0.0024 | 0.0027 | 0.0054 | 0.0338 | 0.0764 | 0.1255 | 0.0940 | 0.1234 | 0.5364 | 11 | 14 | 17 | 31 | 88 | 192 | 303 | 420 | 566 | 0.0364 | 50.81 | 5.936 | 0.4194 | 97252.5 | 57300000 | 38200000000 | 27900000000000 | 0.4410 | 0.1792 | 0.0679 | 0.0012 | 0.2334 | 0.0148 | 0.3166 | 0.1561 | 0.1663 | 0.2149 | 0.0900 | 0.2129 | 0.0748 | 0.1752 | 0.0282 | 0.0907 | 0.0175 | 0.0767 | 0.0053 | 0.0576 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0013 | 0.0006 | 0.0070 | 0.0062 | 0.0449 | 0.0360 | 0.0791 | 0.0719 | 0.0574 | 0.0536 | 0.0936 | 0.0726 | 0.7161 | 0.7591 | 0.0000 | 0.0007 | 0.0007 | 0.0016 | 0.0023 | 0.0042 | 0.0126 | 0.0140 | 0.0555 | 0.0663 | 0.0963 | 0.1117 | 0.0864 | 0.0871 | 0.1164 | 0.1189 | 0.6299 | 0.5955 | 0.0003 | 0.0013 | 0.0012 | 0.0113 | 0.0518 | 0.0818 | 0.0742 | 0.1052 | 0.6728 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1040 | 910 | | 3585 | 10231 | 344.3 | 84.59 | 34.10 | 76.86 | 243 | 270 | 294 | 317 | 338 | 360 | 384 | 412 | 458 | 0.0777 | 795 | 0.975 | 80.16 | 26.08 | 1 | 0.0555 | 199 | 0.0010 | 48.18 | 7.091 | 0.1715 | 125705.0 | 48500000 | 19700000000 | 8380000000000 | 0.4417 | 0.2214 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0058 | 0.0006 | 0.0346 | 0.0056 | 0.1029 | 0.0262 | 0.1587 | 0.0586 | 0.1640 | 0.0586 | 0.1722 | 0.0873 | 0.3583 | 0.7630 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0014 | 0.0006 | 0.0122 | 0.0029 | 0.0480 | 0.0161 | 0.0735 | 0.0365 | 0.0724 | 0.0276 | 0.0882 | 0.0419 | 0.7031 | 0.8745 | 0.0056 | 0.0041 | 0.0014 | 0.0331 | 0.0324 | 0.0455 | 0.0606 | 0.0909 | 0.1437 | 0.2066 | 0.1521 | 0.1901 | 0.1211 | 0.1116 | 0.1563 | 0.1570 | 0.3268 | 0.1612 | 0.0006 | 0.0041 | 0.0094 | 0.0241 | 0.0700 | 0.1329 | 0.0988 | 0.1424 | 0.5176 | 5 | 6 | 6 | 8 | 9 | 10 | 14 | 28 | 84 | 0.2835 | 3.77 | 2.562 | 0.7553 | 7069.4 | 2850000 | 1600000000 | 1100000000000 | 0.6411 | 0.0755 | 0.0751 | 0.0073 | 0.1503 | 0.0125 | 0.2306 | 0.0658 | 0.2098 | 0.1524 | 0.1710 | 0.1994 | 0.0984 | 0.1754 | 0.0492 | 0.1242 | 0.0130 | 0.1420 | 0.0026 | 0.1211 | 0.0063 | 0.0020 | 0.0073 | 0.0041 | 0.0078 | 0.0138 | 0.0195 | 0.0292 | 0.0640 | 0.0604 | 0.0762 | 0.0835 | 0.0703 | 0.0722 | 0.0996 | 0.1078 | 0.6489 | 0.6271 | 0.0012 | 0.0040 | 0.0030 | 0.0020 | 0.0084 | 0.0080 | 0.0247 | 0.0172 | 0.0596 | 0.0669 | 0.0915 | 0.0948 | 0.0686 | 0.0749 | 0.1113 | 0.1021 | 0.6318 | 0.6302 | 0.0027 | 0.0027 | 0.0092 | 0.0223 | 0.0566 | 0.0886 | 0.0691 | 0.1033 | 0.6455 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 137 | 324 | | 5641 | 20747 | 281.5 | 64.71 | 102.70 | 136.65 | 202 | 225 | 243 | 262 | 277 | 293 | 311 | 335 | 366 | 0.0556 | 1153 | 0.979 | 115.25 | 26.87 | 1 | 0.0456 | 257 | 0.0006 | 71.66 | 7.549 | 0.1440 | 83449.7 | 26000000 | 8510000000 | 2920000000000 | 0.4017 | 0.2486 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0038 | 0.0000 | 0.0232 | 0.0027 | 0.0713 | 0.0198 | 0.1447 | 0.0392 | 0.1676 | 0.0472 | 0.1783 | 0.0677 | 0.4103 | 0.8235 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0000 | 0.0102 | 0.0011 | 0.0291 | 0.0141 | 0.0555 | 0.0255 | 0.0700 | 0.0224 | 0.0851 | 0.0349 | 0.7483 | 0.9020 | 0.0009 | 0.0074 | 0.0085 | 0.0257 | 0.0180 | 0.0662 | 0.0722 | 0.1029 | 0.1472 | 0.1838 | 0.1918 | 0.1618 | 0.1149 | 0.1360 | 0.1434 | 0.1140 | 0.3029 | 0.2022 | 0.0023 | 0.0015 | 0.0072 | 0.0281 | 0.0795 | 0.1228 | 0.1049 | 0.1327 | 0.5209 | 11 | 14 | 17 | 23 | 35 | 63 | 115 | 185 | 286 | 0.0458 | 14.71 | 4.863 | 0.5260 | 29220.6 | 12900000 | 7580000000 | 5510000000000 | 0.5276 | 0.1342 | 0.0999 | 0.0045 | 0.3282 | 0.0294 | 0.3393 | 0.1714 | 0.1201 | 0.2314 | 0.0597 | 0.2369 | 0.0285 | 0.1756 | 0.0132 | 0.0762 | 0.0090 | 0.0458 | 0.0021 | 0.0287 | 0.0003 | 0.0002 | 0.0004 | 0.0007 | 0.0014 | 0.0014 | 0.0118 | 0.0117 | 0.0724 | 0.0573 | 0.1165 | 0.1003 | 0.0799 | 0.0698 | 0.1094 | 0.0976 | 0.6080 | 0.6610 | 0.0005 | 0.0006 | 0.0012 | 0.0025 | 0.0034 | 0.0047 | 0.0207 | 0.0211 | 0.0878 | 0.0967 | 0.1435 | 0.1663 | 0.0940 | 0.0978 | 0.1317 | 0.1352 | 0.5172 | 0.4752 | 0.0002 | 0.0006 | 0.0024 | 0.0191 | 0.0743 | 0.1338 | 0.0863 | 0.1178 | 0.5656 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1018 | 411 | | 2600 | 6088 | 103.7 | 24.69 | 101.32 | 87.25 | 73 | 84 | 90 | 96 | 102 | 108 | 114 | 122 | 135 | 0.1304 | 794 | 0.757 | 122.10 | 28.23 | 2 | 0.1200 | 312 | 0.0039 | 11.20 | 5.825 | 0.3318 | 11365.0 | 1320000 | 161000000 | 21000000000 | 0.5268 | 0.1497 | 0.0006 | 0.0000 | 0.0037 | 0.0004 | 0.0141 | 0.0012 | 0.0263 | 0.0050 | 0.0912 | 0.0308 | 0.1769 | 0.0791 | 0.1622 | 0.0579 | 0.1714 | 0.0991 | 0.3537 | 0.7265 | 0.0005 | 0.0000 | 0.0014 | 0.0004 | 0.0038 | 0.0008 | 0.0100 | 0.0031 | 0.0491 | 0.0212 | 0.0920 | 0.0586 | 0.0734 | 0.0358 | 0.0972 | 0.0657 | 0.6725 | 0.8144 | 0.0043 | 0.0071 | 0.0259 | 0.0496 | 0.0237 | 0.0567 | 0.1034 | 0.1064 | 0.1315 | 0.2199 | 0.1810 | 0.1348 | 0.1099 | 0.1277 | 0.1142 | 0.1064 | 0.3060 | 0.1915 | 0.0033 | 0.0033 | 0.0181 | 0.0280 | 0.0954 | 0.1151 | 0.1127 | 0.1332 | 0.4910 | 24 | 33 | 44 | 57 | 72 | 91 | 120 | 163 | 222 | 0.0127 | 11.75 | 5.310 | 0.4411 | 17878.5 | 4610000 | 1580000000 | 681000000000 | 0.5373 | 0.1316 | 0.0246 | 0.0041 | 0.1026 | 0.0157 | 0.2041 | 0.0508 | 0.1688 | 0.1015 | 0.1709 | 0.1614 | 0.1368 | 0.1756 | 0.0887 | 0.1558 | 0.0641 | 0.1355 | 0.0395 | 0.1995 | 0.0022 | 0.0020 | 0.0051 | 0.0055 | 0.0091 | 0.0086 | 0.0215 | 0.0204 | 0.0680 | 0.0540 | 0.1066 | 0.0870 | 0.0844 | 0.0804 | 0.1135 | 0.1042 | 0.5897 | 0.6380 | 0.0022 | 0.0013 | 0.0039 | 0.0053 | 0.0061 | 0.0112 | 0.0259 | 0.0258 | 0.0783 | 0.0998 | 0.1517 | 0.1685 | 0.0998 | 0.1005 | 0.1224 | 0.1375 | 0.5097 | 0.4501 | 0.0027 | 0.0032 | 0.0163 | 0.0195 | 0.0736 | 0.1290 | 0.0940 | 0.1154 | 0.5463 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 735 | 634 | | 3383 | 13602 | 420.5 | 93.73 | 24.16 | 65.07 | 310 | 345 | 369 | 393 | 413 | 435 | 458 | 483 | 531 | 0.0471 | 641 | 0.708 | 187.75 | 42.58 | 1 | 0.1469 | 497 | 0.0008 | 81.64 | 7.362 | 0.1445 | 185607.0 | 86200000 | 42200000000 | 21900000000000 | 0.4414 | 0.2109 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0048 | 0.0000 | 0.0190 | 0.0000 | 0.0557 | 0.0201 | 0.1348 | 0.0447 | 0.1232 | 0.0352 | 0.1517 | 0.0569 | 0.5108 | 0.8430 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0061 | 0.0000 | 0.0327 | 0.0138 | 0.0779 | 0.0312 | 0.0610 | 0.0204 | 0.0832 | 0.0309 | 0.7391 | 0.9038 | 0.0169 | 0.0000 | 0.0127 | 0.0252 | 0.0465 | 0.0377 | 0.0465 | 0.0755 | 0.1269 | 0.1447 | 0.1882 | 0.1698 | 0.0867 | 0.1195 | 0.1501 | 0.1069 | 0.3256 | 0.3208 | 0.0000 | 0.0050 | 0.0126 | 0.0320 | 0.0961 | 0.1420 | 0.1030 | 0.1470 | 0.4623 | 5 | 6 | 7 | 7 | 9 | 10 | 13 | 19 | 43 | 0.1856 | 1.96 | 2.069 | 0.6343 | 4817.1 | 2540000 | 1750000000 | 1330000000000 | 0.5397 | 0.1164 | 0.0580 | 0.0279 | 0.1116 | 0.0343 | 0.1949 | 0.0594 | 0.2024 | 0.1054 | 0.1741 | 0.1577 | 0.1310 | 0.1758 | 0.0759 | 0.1589 | 0.0387 | 0.1368 | 0.0134 | 0.1438 | 0.0052 | 0.0139 | 0.0041 | 0.0154 | 0.0067 | 0.0198 | 0.0191 | 0.0302 | 0.0479 | 0.0395 | 0.0621 | 0.0552 | 0.0592 | 0.0599 | 0.0943 | 0.0738 | 0.7012 | 0.6922 | 0.0010 | 0.0012 | 0.0035 | 0.0035 | 0.0045 | 0.0104 | 0.0205 | 0.0267 | 0.0730 | 0.0818 | 0.0985 | 0.1021 | 0.0725 | 0.0754 | 0.1151 | 0.1155 | 0.6113 | 0.5833 | 0.0026 | 0.0039 | 0.0039 | 0.0176 | 0.0511 | 0.0815 | 0.0686 | 0.1047 | 0.6662 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 802 | 490 | | 8351 | 22610 | 575.7 | 122.92 | 67.00 | 140.53 | 447 | 481 | 507 | 530 | 554 | 578 | 610 | 654 | 726 | 0.0503 | 1138 | 0.892 | 99.02 | 25.02 | 1 | 0.0290 | 242 | 0.0006 | 85.09 | 7.659 | 0.1388 | 346489.0 | 219000000 | 147000000000 | 104000000000000 | 0.4366 | 0.2123 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0000 | 0.0107 | 0.0008 | 0.0464 | 0.0130 | 0.0968 | 0.0349 | 0.1084 | 0.0240 | 0.1476 | 0.0372 | 0.5879 | 0.8901 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0054 | 0.0000 | 0.0254 | 0.0090 | 0.0547 | 0.0192 | 0.0514 | 0.0107 | 0.0823 | 0.0199 | 0.7799 | 0.9412 | 0.0017 | 0.0022 | 0.0111 | 0.0066 | 0.0085 | 0.0087 | 0.0752 | 0.0502 | 0.1265 | 0.1397 | 0.1282 | 0.1790 | 0.0966 | 0.0830 | 0.1154 | 0.1397 | 0.4368 | 0.3908 | 0.0018 | 0.0062 | 0.0117 | 0.0486 | 0.0847 | 0.1260 | 0.0923 | 0.1116 | 0.5173 | 5 | 6 | 7 | 8 | 9 | 11 | 17 | 73 | 234 | 0.2107 | 10.92 | 3.086 | 0.6429 | 24238.2 | 13000000 | 8460000000 | 6260000000000 | 0.4231 | 0.2043 | 0.0750 | 0.0052 | 0.2339 | 0.0353 | 0.2519 | 0.1576 | 0.1589 | 0.1532 | 0.1364 | 0.2054 | 0.0885 | 0.1760 | 0.0390 | 0.1105 | 0.0150 | 0.0913 | 0.0015 | 0.0655 | 0.0000 | 0.0002 | 0.0004 | 0.0006 | 0.0016 | 0.0006 | 0.0084 | 0.0107 | 0.0408 | 0.0369 | 0.0753 | 0.0625 | 0.0404 | 0.0411 | 0.0677 | 0.0705 | 0.7654 | 0.7769 | 0.0002 | 0.0000 | 0.0009 | 0.0005 | 0.0016 | 0.0032 | 0.0125 | 0.0133 | 0.0519 | 0.0529 | 0.0775 | 0.0940 | 0.0542 | 0.0529 | 0.0860 | 0.0876 | 0.7152 | 0.6955 | 0.0002 | 0.0013 | 0.0024 | 0.0124 | 0.0425 | 0.0726 | 0.0494 | 0.0774 | 0.7419 |