High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 818 | 411 | | 1111 | 7364 | 67.7 | 19.08 | 51.50 | 75.73 | 43 | 51 | 58 | 63 | 67 | 72 | 77 | 83 | 92 | 0.0743 | 547 | 0.895 | 205.46 | 68.66 | 1 | 0.5041 | 560 | 0.0025 | 26.29 | 6.146 | 0.2030 | 4951.3 | 386036 | 31800000 | 2760000000 | 0.4919 | 0.1558 | 0.0017 | 0.0000 | 0.0084 | 0.0000 | 0.0506 | 0.0042 | 0.0759 | 0.0116 | 0.1433 | 0.0582 | 0.1855 | 0.0857 | 0.1484 | 0.1228 | 0.2024 | 0.1185 | 0.1838 | 0.5989 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0237 | 0.0078 | 0.0580 | 0.0447 | 0.1018 | 0.0438 | 0.0994 | 0.0720 | 0.1515 | 0.0730 | 0.5657 | 0.7588 | 0.0198 | 0.0241 | 0.0238 | 0.0361 | 0.0437 | 0.1566 | 0.1032 | 0.2289 | 0.1468 | 0.1325 | 0.2103 | 0.1687 | 0.1071 | 0.0602 | 0.1151 | 0.0482 | 0.2302 | 0.1446 | 0.0000 | 0.0036 | 0.0163 | 0.0470 | 0.1501 | 0.1410 | 0.1338 | 0.1591 | 0.3490 | 15 | 17 | 18 | 21 | 24 | 29 | 39 | 59 | 117 | 0.2303 | 3.57 | 2.698 | 0.7805 | 8387.2 | 2780000 | 1260000000 | 683000000000 | 0.4695 | 0.1988 | 0.0338 | 0.0076 | 0.1132 | 0.0146 | 0.2294 | 0.0419 | 0.1779 | 0.1017 | 0.1647 | 0.1773 | 0.1250 | 0.1919 | 0.0632 | 0.1582 | 0.0662 | 0.1264 | 0.0265 | 0.1804 | 0.0057 | 0.0035 | 0.0047 | 0.0053 | 0.0095 | 0.0114 | 0.0218 | 0.0252 | 0.0816 | 0.0650 | 0.1044 | 0.0919 | 0.0745 | 0.0831 | 0.1144 | 0.1136 | 0.5833 | 0.6010 | 0.0007 | 0.0016 | 0.0042 | 0.0032 | 0.0049 | 0.0048 | 0.0329 | 0.0322 | 0.0988 | 0.0893 | 0.1142 | 0.1376 | 0.0883 | 0.0837 | 0.1065 | 0.1255 | 0.5494 | 0.5221 | 0.0029 | 0.0041 | 0.0088 | 0.0269 | 0.0779 | 0.1265 | 0.0715 | 0.1154 | 0.5659 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1049 | 270 | | 3875 | 7952 | 133.1 | 35.91 | 157.83 | 125.74 | 94 | 104 | 113 | 121 | 128 | 136 | 145 | 157 | 179 | 0.0832 | 662 | 0.854 | 78.82 | 25.55 | 2 | 0.0565 | 219 | 0.0020 | 26.25 | 6.494 | 0.2455 | 18997.6 | 2930000 | 490000000 | 89600000000 | 0.4209 | 0.2213 | 0.0000 | 0.0003 | 0.0004 | 0.0000 | 0.0074 | 0.0003 | 0.0302 | 0.0020 | 0.0944 | 0.0294 | 0.1627 | 0.0582 | 0.1605 | 0.0616 | 0.1828 | 0.0913 | 0.3616 | 0.7570 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0030 | 0.0000 | 0.0097 | 0.0003 | 0.0462 | 0.0196 | 0.0716 | 0.0346 | 0.0726 | 0.0291 | 0.1044 | 0.0471 | 0.6921 | 0.8694 | 0.0086 | 0.0097 | 0.0143 | 0.0065 | 0.0399 | 0.0259 | 0.0799 | 0.1003 | 0.1241 | 0.1586 | 0.1526 | 0.1715 | 0.0984 | 0.1100 | 0.1184 | 0.1683 | 0.3638 | 0.2492 | 0.0024 | 0.0083 | 0.0166 | 0.0391 | 0.1073 | 0.1375 | 0.1203 | 0.1316 | 0.4369 | 26 | 44 | 68 | 98 | 128 | 163 | 203 | 251 | 336 | 0.0035 | 41.32 | 6.588 | 0.3220 | 40720.6 | 13800000 | 5550000000 | 2540000000000 | 0.4558 | 0.2138 | 0.0196 | 0.0022 | 0.0713 | 0.0072 | 0.1578 | 0.0421 | 0.1767 | 0.0623 | 0.2000 | 0.1326 | 0.1804 | 0.1870 | 0.1084 | 0.1581 | 0.0531 | 0.1675 | 0.0327 | 0.2410 | 0.0012 | 0.0000 | 0.0015 | 0.0021 | 0.0055 | 0.0037 | 0.0159 | 0.0118 | 0.0585 | 0.0468 | 0.0938 | 0.0773 | 0.0774 | 0.0664 | 0.1074 | 0.0880 | 0.6388 | 0.7040 | 0.0008 | 0.0034 | 0.0053 | 0.0087 | 0.0120 | 0.0135 | 0.0361 | 0.0429 | 0.0847 | 0.1118 | 0.1295 | 0.1301 | 0.1043 | 0.1186 | 0.1401 | 0.1533 | 0.4872 | 0.4178 | 0.0006 | 0.0033 | 0.0108 | 0.0222 | 0.0752 | 0.1049 | 0.0869 | 0.1254 | 0.5707 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1221 | 489 | | 5050 | 9168 | 265.7 | 87.85 | 74.96 | 66.43 | 154 | 189 | 212 | 235 | 259 | 289 | 319 | 348 | 383 | 0.0929 | 852 | 1.188 | 99.54 | 33.29 | 1 | 0.0475 | 240 | 0.0005 | 91.15 | 7.822 | 0.1210 | 78333.9 | 25000000 | 8530000000 | 3070000000000 | 0.5037 | 0.1623 | 0.0005 | 0.0005 | 0.0015 | 0.0000 | 0.0109 | 0.0005 | 0.0583 | 0.0055 | 0.1635 | 0.0478 | 0.2362 | 0.1113 | 0.1517 | 0.0894 | 0.1507 | 0.1313 | 0.2268 | 0.6136 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0006 | 0.0000 | 0.0088 | 0.0024 | 0.0437 | 0.0269 | 0.0917 | 0.0623 | 0.0616 | 0.0423 | 0.0857 | 0.0657 | 0.7070 | 0.8003 | 0.0007 | 0.0031 | 0.0007 | 0.0031 | 0.0080 | 0.0263 | 0.0280 | 0.0789 | 0.0874 | 0.1316 | 0.1475 | 0.1579 | 0.0821 | 0.1300 | 0.1335 | 0.1409 | 0.5120 | 0.3282 | 0.0013 | 0.0021 | 0.0038 | 0.0158 | 0.0554 | 0.1046 | 0.0721 | 0.0900 | 0.6549 | 11 | 16 | 25 | 36 | 53 | 74 | 98 | 128 | 174 | 0.0129 | 12.77 | 5.601 | 0.4237 | 10031.5 | 1760000 | 357000000 | 80500000000 | 0.3984 | 0.2086 | 0.0229 | 0.0012 | 0.0980 | 0.0097 | 0.2408 | 0.0421 | 0.1943 | 0.1069 | 0.1845 | 0.1858 | 0.1176 | 0.1895 | 0.0686 | 0.1656 | 0.0424 | 0.1425 | 0.0310 | 0.1567 | 0.0002 | 0.0004 | 0.0007 | 0.0006 | 0.0047 | 0.0040 | 0.0163 | 0.0144 | 0.0503 | 0.0421 | 0.0822 | 0.0653 | 0.0726 | 0.0593 | 0.0966 | 0.0829 | 0.6764 | 0.7310 | 0.0010 | 0.0016 | 0.0042 | 0.0039 | 0.0065 | 0.0079 | 0.0293 | 0.0347 | 0.0700 | 0.0851 | 0.1059 | 0.1316 | 0.0958 | 0.1056 | 0.1322 | 0.1300 | 0.5550 | 0.4996 | 0.0003 | 0.0030 | 0.0082 | 0.0192 | 0.0604 | 0.0978 | 0.0835 | 0.1173 | 0.6102 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 799 | 497 | | 16816 | 24748 | 122.3 | 34.96 | 236.76 | 206.30 | 82 | 94 | 102 | 110 | 118 | 126 | 136 | 149 | 168 | 0.0650 | 1609 | 1.118 | 72.20 | 25.02 | 3 | 0.0108 | 181 | 0.0021 | 18.82 | 6.539 | 0.2763 | 16190.9 | 2320000 | 358000000 | 60000000000 | 0.4389 | 0.2098 | 0.0010 | 0.0001 | 0.0025 | 0.0003 | 0.0091 | 0.0014 | 0.0328 | 0.0040 | 0.0891 | 0.0250 | 0.1521 | 0.0565 | 0.1545 | 0.0597 | 0.1758 | 0.0901 | 0.3831 | 0.7630 | 0.0004 | 0.0001 | 0.0005 | 0.0000 | 0.0026 | 0.0002 | 0.0095 | 0.0013 | 0.0356 | 0.0130 | 0.0650 | 0.0262 | 0.0618 | 0.0238 | 0.0849 | 0.0395 | 0.7396 | 0.8959 | 0.0031 | 0.0096 | 0.0075 | 0.0071 | 0.0173 | 0.0199 | 0.0537 | 0.1065 | 0.1221 | 0.1508 | 0.1553 | 0.2060 | 0.1205 | 0.1232 | 0.1477 | 0.1521 | 0.3728 | 0.2246 | 0.0013 | 0.0031 | 0.0088 | 0.0298 | 0.0749 | 0.1135 | 0.0977 | 0.1296 | 0.5413 | 21 | 45 | 86 | 134 | 187 | 246 | 312 | 397 | 532 | 0.0053 | 78.87 | 7.190 | 0.2785 | 98609.0 | 53500000 | 34300000000 | 24800000000000 | 0.5106 | 0.1669 | 0.0256 | 0.0012 | 0.1110 | 0.0083 | 0.2322 | 0.0422 | 0.1927 | 0.1005 | 0.1604 | 0.1805 | 0.1290 | 0.2104 | 0.0825 | 0.1584 | 0.0439 | 0.1366 | 0.0227 | 0.1620 | 0.0004 | 0.0002 | 0.0009 | 0.0012 | 0.0050 | 0.0019 | 0.0154 | 0.0099 | 0.0609 | 0.0492 | 0.1064 | 0.0949 | 0.0889 | 0.0752 | 0.1192 | 0.1063 | 0.6028 | 0.6612 | 0.0004 | 0.0013 | 0.0032 | 0.0039 | 0.0100 | 0.0142 | 0.0294 | 0.0412 | 0.0896 | 0.1025 | 0.1454 | 0.1529 | 0.1084 | 0.1139 | 0.1346 | 0.1366 | 0.4791 | 0.4335 | 0.0001 | 0.0020 | 0.0079 | 0.0209 | 0.0743 | 0.1266 | 0.1001 | 0.1318 | 0.5361 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 825 | 684 | | 7651 | 20186 | 434.9 | 80.92 | 100.21 | 97.16 | 337 | 366 | 390 | 409 | 429 | 448 | 471 | 501 | 545 | 0.0502 | 1013 | 1.138 | 102.84 | 33.06 | 1 | 0.0322 | 246 | 0.0009 | 43.02 | 7.234 | 0.1788 | 195716.0 | 91000000 | 43700000000 | 21700000000000 | 0.4528 | 0.2044 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0003 | 0.0109 | 0.0004 | 0.0464 | 0.0156 | 0.1085 | 0.0248 | 0.1193 | 0.0267 | 0.1502 | 0.0416 | 0.5632 | 0.8906 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0047 | 0.0004 | 0.0241 | 0.0132 | 0.0533 | 0.0176 | 0.0554 | 0.0141 | 0.0757 | 0.0217 | 0.7862 | 0.9330 | 0.0026 | 0.0221 | 0.0123 | 0.0608 | 0.0202 | 0.0663 | 0.0792 | 0.1381 | 0.1206 | 0.1547 | 0.1637 | 0.1381 | 0.1021 | 0.1105 | 0.1144 | 0.1050 | 0.3847 | 0.2044 | 0.0011 | 0.0050 | 0.0089 | 0.0319 | 0.0727 | 0.1248 | 0.1040 | 0.1262 | 0.5255 | 9 | 12 | 22 | 46 | 73 | 101 | 133 | 177 | 238 | 0.0261 | 11.79 | 5.435 | 0.4724 | 19482.1 | 5010000 | 1530000000 | 533000000000 | 0.4602 | 0.1900 | 0.0169 | 0.0009 | 0.0928 | 0.0052 | 0.1893 | 0.0424 | 0.1626 | 0.0894 | 0.1630 | 0.1492 | 0.1587 | 0.1861 | 0.0954 | 0.1402 | 0.0745 | 0.1464 | 0.0468 | 0.2402 | 0.0006 | 0.0001 | 0.0007 | 0.0006 | 0.0017 | 0.0015 | 0.0093 | 0.0072 | 0.0425 | 0.0340 | 0.0820 | 0.0612 | 0.0679 | 0.0521 | 0.0976 | 0.0811 | 0.6977 | 0.7621 | 0.0009 | 0.0007 | 0.0013 | 0.0023 | 0.0028 | 0.0042 | 0.0180 | 0.0214 | 0.0688 | 0.0820 | 0.1143 | 0.1324 | 0.0930 | 0.0958 | 0.1199 | 0.1291 | 0.5810 | 0.5321 | 0.0007 | 0.0011 | 0.0034 | 0.0138 | 0.0527 | 0.0963 | 0.0820 | 0.1141 | 0.6359 | ||
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 504 | 454 | | 4632 | 9949 | 526.7 | 103.94 | 144.23 | 161.03 | 403 | 434 | 461 | 488 | 517 | 541 | 573 | 613 | 674 | 0.0767 | 763 | 1.167 | 101.13 | 34.54 | 1 | 0.0531 | 246 | 0.0009 | 55.30 | 7.231 | 0.1624 | 288245.0 | 164000000 | 96700000000 | 59100000000000 | 0.4365 | 0.2052 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0095 | 0.0004 | 0.0653 | 0.0181 | 0.1242 | 0.0349 | 0.1378 | 0.0329 | 0.1714 | 0.0511 | 0.4897 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0044 | 0.0002 | 0.0279 | 0.0136 | 0.0541 | 0.0242 | 0.0597 | 0.0141 | 0.0859 | 0.0249 | 0.7668 | 0.9230 | 0.0054 | 0.0188 | 0.0054 | 0.0125 | 0.0201 | 0.0313 | 0.0698 | 0.1438 | 0.1557 | 0.2438 | 0.1906 | 0.1750 | 0.1302 | 0.1188 | 0.1664 | 0.1563 | 0.2564 | 0.1000 | 0.0009 | 0.0038 | 0.0033 | 0.0302 | 0.0797 | 0.1282 | 0.1249 | 0.1556 | 0.4734 | 18 | 28 | 46 | 67 | 93 | 124 | 163 | 220 | 330 | 0.0156 | 19.65 | 5.459 | 0.4608 | 46729.0 | 24700000 | 17300000000 | 14400000000000 | 0.5530 | 0.1302 | 0.0176 | 0.0010 | 0.1067 | 0.0100 | 0.2360 | 0.0424 | 0.1854 | 0.0883 | 0.1601 | 0.1621 | 0.1292 | 0.2014 | 0.0730 | 0.1717 | 0.0597 | 0.1438 | 0.0323 | 0.1793 | 0.0002 | 0.0000 | 0.0009 | 0.0012 | 0.0024 | 0.0019 | 0.0176 | 0.0129 | 0.0691 | 0.0574 | 0.1203 | 0.0945 | 0.0888 | 0.0781 | 0.1108 | 0.1107 | 0.5899 | 0.6432 | 0.0004 | 0.0009 | 0.0011 | 0.0022 | 0.0061 | 0.0106 | 0.0301 | 0.0396 | 0.1050 | 0.1091 | 0.1384 | 0.1552 | 0.0986 | 0.0994 | 0.1376 | 0.1271 | 0.4828 | 0.4560 | 0.0017 | 0.0012 | 0.0043 | 0.0240 | 0.0822 | 0.1343 | 0.0909 | 0.1308 | 0.5305 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 944 | 643 | | 10766 | 25398 | 77.7 | 26.50 | 79.35 | 104.73 | 50 | 58 | 63 | 68 | 73 | 79 | 85 | 93 | 108 | 0.0568 | 1442 | 1.039 | 62.30 | 19.70 | 12 | 0.0144 | 155 | 0.0021 | 19.33 | 6.548 | 0.2687 | 6739.6 | 660302 | 73500000 | 9260000000 | 0.4514 | 0.1914 | 0.0004 | 0.0001 | 0.0041 | 0.0004 | 0.0155 | 0.0014 | 0.0404 | 0.0069 | 0.0933 | 0.0282 | 0.1426 | 0.0518 | 0.1465 | 0.0640 | 0.1811 | 0.0814 | 0.3762 | 0.7657 | 0.0003 | 0.0000 | 0.0017 | 0.0001 | 0.0045 | 0.0006 | 0.0160 | 0.0048 | 0.0422 | 0.0180 | 0.0703 | 0.0309 | 0.0638 | 0.0353 | 0.1024 | 0.0473 | 0.6987 | 0.8630 | 0.0039 | 0.0067 | 0.0111 | 0.0183 | 0.0261 | 0.0202 | 0.0623 | 0.0577 | 0.1044 | 0.0876 | 0.1358 | 0.1107 | 0.0894 | 0.0808 | 0.1049 | 0.1078 | 0.4621 | 0.5101 | 0.0018 | 0.0078 | 0.0155 | 0.0331 | 0.0750 | 0.0992 | 0.0965 | 0.1223 | 0.5488 | 24 | 27 | 31 | 34 | 39 | 47 | 64 | 99 | 187 | 0.1253 | 4.89 | 3.514 | 0.7026 | 17262.9 | 7360000 | 4380000000 | 3170000000000 | 0.5875 | 0.1331 | 0.0281 | 0.0053 | 0.1260 | 0.0156 | 0.1868 | 0.0425 | 0.1366 | 0.0966 | 0.1545 | 0.1560 | 0.1417 | 0.1683 | 0.1034 | 0.1305 | 0.0757 | 0.1316 | 0.0472 | 0.2536 | 0.0005 | 0.0026 | 0.0029 | 0.0056 | 0.0074 | 0.0082 | 0.0218 | 0.0211 | 0.0702 | 0.0565 | 0.0928 | 0.0744 | 0.0750 | 0.0686 | 0.1091 | 0.0987 | 0.6202 | 0.6644 | 0.0015 | 0.0009 | 0.0017 | 0.0024 | 0.0077 | 0.0079 | 0.0283 | 0.0323 | 0.0924 | 0.0996 | 0.1194 | 0.1287 | 0.0811 | 0.0910 | 0.1267 | 0.1337 | 0.5411 | 0.5034 | 0.0002 | 0.0021 | 0.0070 | 0.0280 | 0.0826 | 0.1089 | 0.0754 | 0.1199 | 0.5761 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 684 | 361 | | 399 | 6206 | 58.4 | 9.74 | 24.73 | 66.86 | 46 | 49 | 52 | 54 | 57 | 61 | 64 | 69 | 72 | 0.1017 | 631 | 0.682 | 36.24 | 8.54 | 1 | 0.2607 | 104 | 0.0248 | 2.23 | 3.908 | 0.5277 | 3503.6 | 215851 | 13600000 | 881000000 | 0.3536 | 0.2676 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0071 | 0.0000 | 0.0426 | 0.0101 | 0.0922 | 0.0628 | 0.1525 | 0.0678 | 0.1489 | 0.0653 | 0.1915 | 0.0879 | 0.3617 | 0.7060 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0225 | 0.0100 | 0.0535 | 0.0627 | 0.0817 | 0.0677 | 0.0789 | 0.0652 | 0.1042 | 0.0677 | 0.6563 | 0.7268 | 0.0137 | 1.0000 | 0.0000 | 0.0000 | 0.0274 | 0.0000 | 0.0822 | 0.0000 | 0.0822 | 0.0000 | 0.1781 | 0.0000 | 0.1370 | 0.0000 | 0.2055 | 0.0000 | 0.2740 | 0.0000 | 0.0053 | 0.0053 | 0.0159 | 0.0265 | 0.0635 | 0.1111 | 0.1058 | 0.0899 | 0.5767 | 5 | 6 | 7 | 8 | 9 | 10 | 13 | 18 | 40 | 0.3348 | 9.79 | 2.064 | 0.7707 | 5081.6 | 2730000 | 1940000000 | 1570000000000 | 0.6341 | 0.0846 | 0.0349 | 0.0330 | 0.1163 | 0.0366 | 0.1453 | 0.0425 | 0.1628 | 0.0837 | 0.2006 | 0.1262 | 0.1919 | 0.1498 | 0.1163 | 0.1462 | 0.0233 | 0.1686 | 0.0087 | 0.2134 | 0.0053 | 0.0181 | 0.0079 | 0.0194 | 0.0184 | 0.0148 | 0.0202 | 0.0258 | 0.0746 | 0.0523 | 0.0886 | 0.0690 | 0.0912 | 0.0800 | 0.1202 | 0.1052 | 0.5737 | 0.6155 | 0.0025 | 0.0028 | 0.0013 | 0.0000 | 0.0088 | 0.0043 | 0.0251 | 0.0256 | 0.0842 | 0.0954 | 0.1256 | 0.1439 | 0.0942 | 0.1068 | 0.1344 | 0.1296 | 0.5239 | 0.4915 | 0.0022 | 0.0098 | 0.0065 | 0.0271 | 0.0869 | 0.0912 | 0.0988 | 0.1325 | 0.5451 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1052 | 425 | | 3025 | 6544 | 395.4 | 125.68 | 137.78 | 188.28 | 223 | 262 | 321 | 379 | 427 | 461 | 488 | 513 | 538 | 0.0767 | 502 | 0.961 | 105.32 | 29.00 | 2 | 0.0826 | 250 | 0.0010 | 36.99 | 7.117 | 0.2145 | 172122.0 | 79400000 | 38000000000 | 18700000000000 | 0.3829 | 0.2510 | 0.0000 | 0.0004 | 0.0066 | 0.0000 | 0.0094 | 0.0020 | 0.0169 | 0.0065 | 0.0778 | 0.0296 | 0.1321 | 0.0455 | 0.0965 | 0.0386 | 0.1781 | 0.0771 | 0.4827 | 0.8002 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0008 | 0.0014 | 0.0034 | 0.0182 | 0.0191 | 0.0383 | 0.0309 | 0.0163 | 0.0202 | 0.0299 | 0.0313 | 0.8954 | 0.8944 | 0.0019 | 0.0438 | 0.0028 | 0.0500 | 0.0112 | 0.0813 | 0.0168 | 0.0625 | 0.0493 | 0.1125 | 0.0503 | 0.1250 | 0.0615 | 0.1438 | 0.0829 | 0.1250 | 0.7235 | 0.2563 | 0.0000 | 0.0000 | 0.0012 | 0.0058 | 0.0226 | 0.0423 | 0.0359 | 0.0469 | 0.8454 | 11 | 15 | 21 | 35 | 61 | 94 | 140 | 217 | 376 | 0.0253 | 45.28 | 5.475 | 0.4795 | 54428.7 | 33000000 | 24600000000 | 20600000000000 | 0.5487 | 0.1238 | 0.0167 | 0.0007 | 0.0866 | 0.0051 | 0.1596 | 0.0425 | 0.1368 | 0.0717 | 0.1733 | 0.1281 | 0.1459 | 0.1801 | 0.1277 | 0.1274 | 0.0745 | 0.1384 | 0.0790 | 0.3060 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0017 | 0.0014 | 0.0118 | 0.0099 | 0.0557 | 0.0437 | 0.0861 | 0.0757 | 0.0621 | 0.0493 | 0.0807 | 0.0746 | 0.7002 | 0.7454 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0082 | 0.0068 | 0.0211 | 0.0271 | 0.0637 | 0.0780 | 0.1129 | 0.1248 | 0.0825 | 0.0753 | 0.0953 | 0.1031 | 0.6152 | 0.5848 | 0.0000 | 0.0010 | 0.0035 | 0.0129 | 0.0662 | 0.1005 | 0.0672 | 0.0985 | 0.6502 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 619 | 861 | | 3334 | 9894 | 194.2 | 63.45 | 194.29 | 151.46 | 124 | 139 | 154 | 168 | 183 | 201 | 221 | 246 | 280 | 0.0730 | 722 | 0.462 | 118.15 | 25.02 | 1 | 0.1041 | 347 | 0.0006 | 128.05 | 7.588 | 0.1119 | 41739.0 | 9880000 | 2560000000 | 721000000000 | 0.4295 | 0.2204 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0200 | 0.0015 | 0.0524 | 0.0063 | 0.1427 | 0.0431 | 0.1999 | 0.0822 | 0.1730 | 0.0778 | 0.1675 | 0.1202 | 0.2426 | 0.6690 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0039 | 0.0000 | 0.0144 | 0.0039 | 0.0471 | 0.0228 | 0.0781 | 0.0449 | 0.0663 | 0.0308 | 0.0938 | 0.0555 | 0.6958 | 0.8421 | 0.0012 | 0.0050 | 0.0024 | 0.0050 | 0.0060 | 0.0298 | 0.0393 | 0.0720 | 0.1262 | 0.1687 | 0.1738 | 0.1687 | 0.0952 | 0.1092 | 0.1333 | 0.1365 | 0.4226 | 0.3052 | 0.0014 | 0.0014 | 0.0082 | 0.0199 | 0.0694 | 0.1223 | 0.0804 | 0.1154 | 0.5817 | 32 | 63 | 95 | 127 | 160 | 199 | 246 | 304 | 396 | 0.0037 | 29.49 | 6.429 | 0.2958 | 60686.3 | 25300000 | 12900000000 | 7630000000000 | 0.5774 | 0.1179 | 0.0296 | 0.0011 | 0.1266 | 0.0053 | 0.2181 | 0.0429 | 0.1967 | 0.0911 | 0.1622 | 0.1735 | 0.1184 | 0.2026 | 0.0789 | 0.1626 | 0.0488 | 0.1505 | 0.0208 | 0.1703 | 0.0002 | 0.0002 | 0.0010 | 0.0002 | 0.0034 | 0.0016 | 0.0232 | 0.0134 | 0.0774 | 0.0517 | 0.1295 | 0.0963 | 0.1053 | 0.0884 | 0.1348 | 0.1199 | 0.5252 | 0.6283 | 0.0006 | 0.0032 | 0.0043 | 0.0073 | 0.0115 | 0.0218 | 0.0449 | 0.0638 | 0.1172 | 0.1344 | 0.1596 | 0.1707 | 0.1206 | 0.1287 | 0.1522 | 0.1493 | 0.3890 | 0.3208 | 0.0015 | 0.0027 | 0.0089 | 0.0332 | 0.0904 | 0.1524 | 0.1096 | 0.1362 | 0.4652 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 97 | 112 | | 5113 | 8192 | 129.9 | 36.86 | 92.19 | 68.78 | 88 | 99 | 108 | 116 | 124 | 132 | 143 | 158 | 180 | 0.0880 | 721 | 0.824 | 96.80 | 28.65 | 1 | 0.0522 | 267 | 0.0018 | 30.75 | 6.658 | 0.2188 | 18224.4 | 2770000 | 455000000 | 80700000000 | 0.4297 | 0.2183 | 0.0015 | 0.0000 | 0.0026 | 0.0000 | 0.0139 | 0.0007 | 0.0530 | 0.0054 | 0.1258 | 0.0349 | 0.1869 | 0.0641 | 0.1767 | 0.0747 | 0.1818 | 0.1217 | 0.2579 | 0.6985 | 0.0008 | 0.0000 | 0.0008 | 0.0000 | 0.0042 | 0.0006 | 0.0117 | 0.0014 | 0.0481 | 0.0188 | 0.0817 | 0.0338 | 0.0838 | 0.0294 | 0.1202 | 0.0555 | 0.6488 | 0.8604 | 0.0063 | 0.0204 | 0.0108 | 0.0102 | 0.0270 | 0.0469 | 0.0685 | 0.1082 | 0.1360 | 0.1837 | 0.1586 | 0.1694 | 0.1342 | 0.1327 | 0.1441 | 0.1449 | 0.3144 | 0.1837 | 0.0014 | 0.0095 | 0.0181 | 0.0443 | 0.0863 | 0.1270 | 0.1116 | 0.1554 | 0.4465 | 24 | 35 | 45 | 57 | 71 | 88 | 114 | 146 | 193 | 0.0043 | 25.07 | 6.144 | 0.3098 | 13228.5 | 2490000 | 551000000 | 137000000000 | 0.5801 | 0.1203 | 0.0269 | 0.0031 | 0.1281 | 0.0165 | 0.2307 | 0.0429 | 0.2162 | 0.1016 | 0.1645 | 0.1799 | 0.1303 | 0.1947 | 0.0604 | 0.1648 | 0.0306 | 0.1384 | 0.0124 | 0.1580 | 0.0018 | 0.0014 | 0.0038 | 0.0038 | 0.0092 | 0.0048 | 0.0272 | 0.0198 | 0.0768 | 0.0577 | 0.1064 | 0.0859 | 0.0913 | 0.0839 | 0.1379 | 0.1141 | 0.5455 | 0.6286 | 0.0008 | 0.0014 | 0.0031 | 0.0058 | 0.0102 | 0.0144 | 0.0403 | 0.0471 | 0.1009 | 0.1215 | 0.1498 | 0.1686 | 0.1139 | 0.1311 | 0.1573 | 0.1662 | 0.4237 | 0.3439 | 0.0022 | 0.0035 | 0.0104 | 0.0371 | 0.0815 | 0.1255 | 0.1107 | 0.1375 | 0.4917 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 917 | 765 | | 4787 | 6025 | 134.0 | 29.36 | 199.47 | 144.31 | 101 | 111 | 117 | 124 | 130 | 137 | 145 | 154 | 168 | 0.1200 | 723 | 1.159 | 112.49 | 39.01 | 1 | 0.0570 | 273 | 0.0026 | 20.01 | 6.253 | 0.2547 | 18810.6 | 2780000 | 434000000 | 72000000000 | 0.4427 | 0.2093 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0064 | 0.0013 | 0.0155 | 0.0016 | 0.0709 | 0.0202 | 0.1267 | 0.0377 | 0.1506 | 0.0388 | 0.1815 | 0.0566 | 0.4467 | 0.8438 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0073 | 0.0004 | 0.0405 | 0.0149 | 0.0653 | 0.0246 | 0.0710 | 0.0181 | 0.0965 | 0.0305 | 0.7169 | 0.9114 | 0.0043 | 0.0000 | 0.0157 | 0.0082 | 0.0443 | 0.0286 | 0.0944 | 0.1224 | 0.1688 | 0.1510 | 0.1574 | 0.2041 | 0.0987 | 0.1102 | 0.1273 | 0.1224 | 0.2890 | 0.2531 | 0.0018 | 0.0042 | 0.0125 | 0.0365 | 0.0983 | 0.1347 | 0.1117 | 0.1440 | 0.4564 | 44 | 68 | 100 | 134 | 171 | 211 | 256 | 309 | 392 | 0.0015 | 70.67 | 7.066 | 0.2195 | 60610.6 | 23900000 | 11300000000 | 6160000000000 | 0.5305 | 0.1272 | 0.0202 | 0.0004 | 0.0960 | 0.0047 | 0.2098 | 0.0436 | 0.2030 | 0.0781 | 0.1955 | 0.1872 | 0.1348 | 0.1919 | 0.0851 | 0.1725 | 0.0447 | 0.1552 | 0.0110 | 0.1665 | 0.0006 | 0.0003 | 0.0009 | 0.0005 | 0.0019 | 0.0026 | 0.0206 | 0.0127 | 0.0768 | 0.0560 | 0.1070 | 0.0915 | 0.0989 | 0.0710 | 0.1385 | 0.1099 | 0.5548 | 0.6556 | 0.0015 | 0.0032 | 0.0064 | 0.0097 | 0.0124 | 0.0175 | 0.0500 | 0.0662 | 0.1199 | 0.1364 | 0.1640 | 0.1857 | 0.1189 | 0.1422 | 0.1690 | 0.1513 | 0.3578 | 0.2877 | 0.0008 | 0.0008 | 0.0077 | 0.0291 | 0.0926 | 0.1403 | 0.1170 | 0.1592 | 0.4525 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1086 | 620 | | 4452 | 3745 | 173.1 | 35.31 | 160.12 | 114.34 | 133 | 145 | 153 | 161 | 169 | 177 | 186 | 197 | 216 | 0.1522 | 570 | 1.194 | 77.34 | 28.86 | 1 | 0.0442 | 197 | 0.0021 | 21.97 | 6.469 | 0.2475 | 31225.1 | 5890000 | 1170000000 | 246000000000 | 0.3936 | 0.2497 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0053 | 0.0002 | 0.0175 | 0.0012 | 0.0519 | 0.0169 | 0.1051 | 0.0386 | 0.1236 | 0.0286 | 0.1721 | 0.0435 | 0.5232 | 0.8710 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0100 | 0.0009 | 0.0257 | 0.0133 | 0.0524 | 0.0252 | 0.0561 | 0.0137 | 0.0820 | 0.0252 | 0.7704 | 0.9216 | 0.0032 | 0.0056 | 0.0323 | 0.0113 | 0.0258 | 0.0339 | 0.0855 | 0.0734 | 0.1403 | 0.1864 | 0.1645 | 0.2034 | 0.1339 | 0.0847 | 0.1339 | 0.1073 | 0.2806 | 0.2938 | 0.0020 | 0.0039 | 0.0158 | 0.0331 | 0.0805 | 0.1051 | 0.1111 | 0.1362 | 0.5123 | 40 | 68 | 87 | 108 | 131 | 156 | 189 | 244 | 330 | 0.0027 | 39.04 | 6.449 | 0.3029 | 38710.2 | 12200000 | 4630000000 | 1970000000000 | 0.4732 | 0.1655 | 0.0072 | 0.0025 | 0.0929 | 0.0144 | 0.1158 | 0.0439 | 0.1411 | 0.0640 | 0.1496 | 0.1193 | 0.1604 | 0.1532 | 0.1086 | 0.1293 | 0.0989 | 0.1494 | 0.1255 | 0.3239 | 0.0021 | 0.0012 | 0.0031 | 0.0032 | 0.0093 | 0.0057 | 0.0260 | 0.0114 | 0.0639 | 0.0584 | 0.1070 | 0.0852 | 0.0826 | 0.0697 | 0.1158 | 0.1010 | 0.5903 | 0.6642 | 0.0027 | 0.0011 | 0.0046 | 0.0057 | 0.0146 | 0.0137 | 0.0401 | 0.0538 | 0.0866 | 0.0985 | 0.1486 | 0.1546 | 0.0902 | 0.1168 | 0.1395 | 0.1730 | 0.4731 | 0.3826 | 0.0021 | 0.0041 | 0.0110 | 0.0336 | 0.0782 | 0.1221 | 0.0912 | 0.1276 | 0.5302 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 213 | 896 | | 3746 | 14440 | 324.0 | 67.68 | 163.52 | 174.35 | 235 | 267 | 288 | 305 | 322 | 340 | 359 | 382 | 414 | 0.0614 | 886 | 1.026 | 90.35 | 31.58 | 1 | 0.0670 | 251 | 0.0007 | 89.85 | 7.502 | 0.1378 | 109544.0 | 38500000 | 14000000000 | 5270000000000 | 0.4313 | 0.2081 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0008 | 0.0143 | 0.0014 | 0.0573 | 0.0161 | 0.1297 | 0.0417 | 0.1481 | 0.0296 | 0.1661 | 0.0735 | 0.4822 | 0.8369 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0052 | 0.0014 | 0.0223 | 0.0128 | 0.0419 | 0.0312 | 0.0461 | 0.0115 | 0.0652 | 0.0325 | 0.8187 | 0.9101 | 0.0015 | 0.0741 | 0.0092 | 0.0556 | 0.0382 | 0.0926 | 0.0947 | 0.1667 | 0.1740 | 0.1852 | 0.1969 | 0.1481 | 0.1191 | 0.0926 | 0.1481 | 0.1111 | 0.2183 | 0.0741 | 0.0000 | 0.0005 | 0.0054 | 0.0264 | 0.0696 | 0.1192 | 0.1154 | 0.1472 | 0.5162 | 13 | 17 | 27 | 55 | 99 | 150 | 212 | 304 | 427 | 0.0207 | 22.64 | 5.797 | 0.4177 | 57133.8 | 26400000 | 14400000000 | 8750000000000 | 0.5240 | 0.1275 | 0.0365 | 0.0012 | 0.1204 | 0.0053 | 0.1762 | 0.0439 | 0.2018 | 0.1082 | 0.1883 | 0.1766 | 0.1249 | 0.1778 | 0.0762 | 0.1466 | 0.0532 | 0.1487 | 0.0224 | 0.1917 | 0.0006 | 0.0004 | 0.0018 | 0.0006 | 0.0042 | 0.0024 | 0.0165 | 0.0138 | 0.0564 | 0.0447 | 0.0762 | 0.0656 | 0.0665 | 0.0531 | 0.0911 | 0.0798 | 0.6869 | 0.7397 | 0.0013 | 0.0013 | 0.0019 | 0.0043 | 0.0055 | 0.0080 | 0.0249 | 0.0268 | 0.0675 | 0.0771 | 0.0949 | 0.1009 | 0.0777 | 0.0746 | 0.0971 | 0.0949 | 0.6292 | 0.6123 | 0.0004 | 0.0022 | 0.0050 | 0.0187 | 0.0604 | 0.0872 | 0.0731 | 0.1006 | 0.6523 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1053 | 104 | | 2330 | 7315 | 404.0 | 189.76 | 84.83 | 144.30 | 168 | 214 | 264 | 314 | 375 | 453 | 527 | 592 | 678 | 0.0932 | 682 | 0.598 | 100.02 | 13.89 | 5 | 0.0927 | 216 | 0.0009 | 43.35 | 7.214 | 0.1661 | 199239.0 | 112000000 | 68300000000 | 44000000000000 | 0.3454 | 0.2664 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0000 | 0.0317 | 0.0172 | 0.1329 | 0.0499 | 0.2341 | 0.0946 | 0.2004 | 0.0851 | 0.1786 | 0.0997 | 0.2143 | 0.6535 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0060 | 0.0052 | 0.0268 | 0.0215 | 0.0357 | 0.0302 | 0.0402 | 0.0279 | 0.0462 | 0.0296 | 0.8444 | 0.8857 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0024 | 0.0000 | 0.0060 | 0.0107 | 0.0441 | 0.0661 | 0.0691 | 0.0946 | 0.0524 | 0.0643 | 0.0799 | 0.1143 | 0.7461 | 0.6482 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0399 | 0.0463 | 0.0399 | 0.0704 | 0.7998 | 21 | 27 | 31 | 34 | 38 | 44 | 54 | 94 | 219 | 0.1318 | 7.03 | 3.250 | 0.7401 | 28015.3 | 26600000 | 42300000000 | 80500000000000 | 0.5119 | 0.1569 | 0.0219 | 0.0200 | 0.0820 | 0.0234 | 0.1530 | 0.0443 | 0.1995 | 0.0747 | 0.2158 | 0.1354 | 0.1503 | 0.1458 | 0.0956 | 0.1519 | 0.0601 | 0.1632 | 0.0219 | 0.2413 | 0.0028 | 0.0096 | 0.0062 | 0.0104 | 0.0068 | 0.0183 | 0.0186 | 0.0246 | 0.0361 | 0.0445 | 0.0559 | 0.0512 | 0.0514 | 0.0608 | 0.0745 | 0.0908 | 0.7477 | 0.6898 | 0.0000 | 0.0000 | 0.0014 | 0.0032 | 0.0057 | 0.0064 | 0.0135 | 0.0216 | 0.0519 | 0.0632 | 0.0811 | 0.0800 | 0.0597 | 0.0752 | 0.0989 | 0.0992 | 0.6878 | 0.6512 | 0.0000 | 0.0000 | 0.0052 | 0.0181 | 0.0413 | 0.0664 | 0.0529 | 0.0896 | 0.7266 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1165 | 419 | | 423 | 1848 | 89.8 | 13.38 | 5.99 | 2.24 | 70 | 76 | 82 | 87 | 92 | 96 | 99 | 102 | 106 | 0.1580 | 292 | 0.987 | 101.21 | 28.84 | 2 | 0.5816 | 246 | 0.0855 | 0.62 | 2.720 | 0.7418 | 8238.7 | 771134 | 73500000 | 7110000000 | 0.4178 | 0.2216 | 0.0000 | 0.0000 | 0.0060 | 0.0000 | 0.0149 | 0.0000 | 0.0268 | 0.0071 | 0.0893 | 0.0567 | 0.1220 | 0.0946 | 0.1369 | 0.0520 | 0.1964 | 0.0827 | 0.4077 | 0.7069 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0109 | 0.0000 | 0.0218 | 0.0071 | 0.0708 | 0.0567 | 0.0627 | 0.0946 | 0.0518 | 0.0520 | 0.0681 | 0.0827 | 0.7084 | 0.7069 | 0.0968 | 0.0000 | 0.2581 | 0.0000 | 0.2581 | 0.0000 | 0.1613 | 0.0000 | 0.0968 | 0.0000 | 0.0968 | 0.0000 | 0.0323 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0128 | 0.0213 | 0.0383 | 0.0553 | 0.0596 | 0.0851 | 0.1532 | 0.5745 | 3 | 4 | 5 | 6 | 6 | 6 | 7 | 8 | 9 | 0.0815 | 0.39 | 0.827 | 0.2673 | 40.9 | 306.966 | 2499.9 | 21880.8 | 0.5165 | 0.1403 | 0.0116 | 0.0008 | 0.0474 | 0.0055 | 0.1063 | 0.0444 | 0.2358 | 0.1014 | 0.2716 | 0.1846 | 0.1884 | 0.2472 | 0.1011 | 0.2274 | 0.0316 | 0.1450 | 0.0063 | 0.0436 | 0.0000 | 0.0000 | 0.0041 | 0.0020 | 0.0186 | 0.0118 | 0.0592 | 0.0341 | 0.1171 | 0.1076 | 0.1860 | 0.1594 | 0.2404 | 0.2270 | 0.2424 | 0.2782 | 0.1322 | 0.1798 | 0.1036 | 0.3053 | 0.2490 | 0.2824 | 0.2829 | 0.1756 | 0.1972 | 0.0954 | 0.1056 | 0.0916 | 0.0418 | 0.0305 | 0.0179 | 0.0153 | 0.0020 | 0.0038 | 0.0000 | 0.0000 | 0.0026 | 0.0290 | 0.0729 | 0.1747 | 0.2186 | 0.2151 | 0.1449 | 0.1010 | 0.0413 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1170 | 829 | | 5625 | 11492 | 469.5 | 111.56 | 192.86 | 189.26 | 337 | 410 | 439 | 458 | 475 | 495 | 522 | 556 | 596 | 0.0699 | 803 | 0.905 | 84.12 | 26.57 | 4 | 0.0398 | 224 | 0.0027 | 17.91 | 6.386 | 0.3047 | 232826.0 | 120000000 | 63700000000 | 34800000000000 | 0.4179 | 0.2125 | 0.0008 | 0.0000 | 0.0003 | 0.0000 | 0.0023 | 0.0000 | 0.0132 | 0.0004 | 0.0347 | 0.0157 | 0.0700 | 0.0305 | 0.0692 | 0.0190 | 0.0975 | 0.0353 | 0.7120 | 0.8991 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0140 | 0.0121 | 0.0255 | 0.0227 | 0.0261 | 0.0113 | 0.0364 | 0.0204 | 0.8962 | 0.9335 | 0.0030 | 0.0128 | 0.0080 | 0.0064 | 0.0189 | 0.0321 | 0.0427 | 0.0641 | 0.0895 | 0.1154 | 0.1123 | 0.2051 | 0.1203 | 0.1090 | 0.1252 | 0.1474 | 0.4801 | 0.3077 | 0.0023 | 0.0030 | 0.0056 | 0.0251 | 0.0422 | 0.0700 | 0.0812 | 0.0888 | 0.6818 | 7 | 11 | 32 | 83 | 150 | 207 | 272 | 351 | 468 | 0.0155 | 17.10 | 5.622 | 0.3721 | 73008.9 | 34800000 | 19300000000 | 12000000000000 | 0.4101 | 0.2114 | 0.0192 | 0.0004 | 0.1141 | 0.0067 | 0.2050 | 0.0445 | 0.1566 | 0.1012 | 0.1559 | 0.1709 | 0.1533 | 0.2112 | 0.0922 | 0.1401 | 0.0591 | 0.1257 | 0.0445 | 0.1993 | 0.0002 | 0.0000 | 0.0007 | 0.0006 | 0.0014 | 0.0008 | 0.0078 | 0.0063 | 0.0471 | 0.0404 | 0.0894 | 0.0708 | 0.0685 | 0.0552 | 0.0980 | 0.0723 | 0.6870 | 0.7536 | 0.0000 | 0.0003 | 0.0034 | 0.0029 | 0.0058 | 0.0081 | 0.0171 | 0.0318 | 0.0772 | 0.0837 | 0.1322 | 0.1470 | 0.0849 | 0.1040 | 0.1207 | 0.1132 | 0.5586 | 0.5091 | 0.0004 | 0.0012 | 0.0039 | 0.0173 | 0.0618 | 0.1044 | 0.0853 | 0.1164 | 0.6093 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 318 | 624 | | 6835 | 14487 | 545.4 | 80.10 | 171.75 | 314.77 | 430 | 485 | 516 | 537 | 554 | 568 | 585 | 605 | 635 | 0.0583 | 845 | 0.559 | 146.51 | 30.07 | 3 | 0.0660 | 451 | 0.0011 | 31.34 | 7.160 | 0.2167 | 303826.0 | 173000000 | 99800000000 | 58700000000000 | 0.4423 | 0.2040 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0046 | 0.0007 | 0.0219 | 0.0105 | 0.0376 | 0.0227 | 0.0393 | 0.0121 | 0.0589 | 0.0224 | 0.8363 | 0.9315 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0006 | 0.0138 | 0.0100 | 0.0230 | 0.0208 | 0.0226 | 0.0098 | 0.0272 | 0.0183 | 0.9111 | 0.9405 | 0.0093 | 0.0000 | 0.0163 | 0.0000 | 0.0280 | 0.0000 | 0.0676 | 0.0000 | 0.1189 | 0.0000 | 0.1352 | 0.0000 | 0.1119 | 0.0000 | 0.1119 | 0.0000 | 0.4009 | 0.0000 | 0.0008 | 0.0005 | 0.0050 | 0.0188 | 0.0379 | 0.0636 | 0.0767 | 0.0981 | 0.6986 | 11 | 13 | 15 | 19 | 25 | 47 | 102 | 252 | 575 | 0.1437 | 10.43 | 3.781 | 0.6289 | 128574.0 | 142000000 | 187000000000 | 273000000000000 | 0.3937 | 0.2546 | 0.0244 | 0.0022 | 0.0822 | 0.0126 | 0.1735 | 0.0445 | 0.1903 | 0.0867 | 0.2116 | 0.1890 | 0.1248 | 0.1883 | 0.0868 | 0.1401 | 0.0715 | 0.1371 | 0.0350 | 0.1994 | 0.0000 | 0.0005 | 0.0010 | 0.0007 | 0.0036 | 0.0030 | 0.0067 | 0.0079 | 0.0359 | 0.0345 | 0.0508 | 0.0483 | 0.0398 | 0.0391 | 0.0646 | 0.0606 | 0.7976 | 0.8055 | 0.0009 | 0.0007 | 0.0009 | 0.0010 | 0.0028 | 0.0020 | 0.0080 | 0.0081 | 0.0423 | 0.0430 | 0.0537 | 0.0696 | 0.0515 | 0.0545 | 0.0771 | 0.0794 | 0.7628 | 0.7418 | 0.0006 | 0.0014 | 0.0023 | 0.0093 | 0.0369 | 0.0544 | 0.0417 | 0.0668 | 0.7866 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 212 | 744 | | 6614 | 10325 | 163.1 | 32.35 | 119.28 | 84.78 | 125 | 138 | 147 | 155 | 161 | 167 | 175 | 185 | 203 | 0.0792 | 818 | 1.172 | 127.35 | 40.25 | 1 | 0.0452 | 299 | 0.0020 | 27.70 | 6.559 | 0.2300 | 27650.6 | 4880000 | 902000000 | 175000000000 | 0.4500 | 0.2031 | 0.0002 | 0.0000 | 0.0008 | 0.0003 | 0.0033 | 0.0005 | 0.0157 | 0.0009 | 0.0518 | 0.0158 | 0.1045 | 0.0311 | 0.1239 | 0.0356 | 0.1680 | 0.0538 | 0.5318 | 0.8621 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0073 | 0.0005 | 0.0238 | 0.0110 | 0.0514 | 0.0224 | 0.0550 | 0.0146 | 0.0835 | 0.0286 | 0.7771 | 0.9229 | 0.0114 | 0.0090 | 0.0194 | 0.0495 | 0.0411 | 0.0495 | 0.1006 | 0.1802 | 0.1600 | 0.2117 | 0.1794 | 0.1757 | 0.1486 | 0.0991 | 0.1394 | 0.0991 | 0.2000 | 0.1261 | 0.0006 | 0.0063 | 0.0157 | 0.0466 | 0.0913 | 0.1326 | 0.1222 | 0.1698 | 0.4148 | 30 | 47 | 62 | 79 | 97 | 119 | 148 | 185 | 240 | 0.0026 | 32.10 | 6.579 | 0.2832 | 21415.5 | 4970000 | 1370000000 | 425000000000 | 0.5726 | 0.1051 | 0.0233 | 0.0012 | 0.1341 | 0.0059 | 0.2743 | 0.0446 | 0.1832 | 0.1006 | 0.1522 | 0.1877 | 0.1071 | 0.1954 | 0.0694 | 0.1475 | 0.0367 | 0.1460 | 0.0197 | 0.1709 | 0.0004 | 0.0005 | 0.0023 | 0.0009 | 0.0082 | 0.0027 | 0.0218 | 0.0148 | 0.0827 | 0.0624 | 0.1269 | 0.0968 | 0.1019 | 0.0859 | 0.1392 | 0.1237 | 0.5166 | 0.6124 | 0.0015 | 0.0023 | 0.0073 | 0.0051 | 0.0094 | 0.0167 | 0.0462 | 0.0607 | 0.1152 | 0.1293 | 0.1711 | 0.1795 | 0.1100 | 0.1215 | 0.1510 | 0.1484 | 0.3883 | 0.3364 | 0.0007 | 0.0041 | 0.0070 | 0.0374 | 0.0934 | 0.1539 | 0.1074 | 0.1421 | 0.4540 | ||
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1108 | 239 | | 5108 | 12529 | 286.7 | 70.87 | 214.74 | 352.40 | 171 | 236 | 266 | 284 | 299 | 315 | 328 | 344 | 365 | 0.0797 | 998 | 0.558 | 111.13 | 15.52 | 4 | 0.0484 | 247 | 0.0020 | 16.33 | 6.555 | 0.2615 | 87243.0 | 27600000 | 9000000000 | 3000000000000 | 0.3894 | 0.2353 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0025 | 0.0004 | 0.0143 | 0.0011 | 0.0584 | 0.0180 | 0.0901 | 0.0332 | 0.0841 | 0.0276 | 0.1336 | 0.0427 | 0.6155 | 0.8769 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0007 | 0.0180 | 0.0141 | 0.0245 | 0.0255 | 0.0159 | 0.0137 | 0.0327 | 0.0196 | 0.9084 | 0.9264 | 0.0060 | 0.0200 | 0.0109 | 0.1000 | 0.0268 | 0.1400 | 0.0625 | 0.1500 | 0.1240 | 0.1900 | 0.1488 | 0.1800 | 0.1399 | 0.1200 | 0.1290 | 0.0700 | 0.3522 | 0.0300 | 0.0013 | 0.0007 | 0.0040 | 0.0131 | 0.0368 | 0.0646 | 0.0703 | 0.1078 | 0.7014 | 8 | 10 | 13 | 17 | 22 | 32 | 138 | 460 | 810 | 0.1100 | 11.85 | 3.914 | 0.5579 | 170291.0 | 167000000 | 181000000000 | 211000000000000 | 0.5996 | 0.0926 | 0.0347 | 0.0084 | 0.1262 | 0.0139 | 0.2429 | 0.0446 | 0.1767 | 0.0990 | 0.2019 | 0.1660 | 0.1703 | 0.2106 | 0.0315 | 0.1381 | 0.0126 | 0.1367 | 0.0032 | 0.1827 | 0.0006 | 0.0000 | 0.0006 | 0.0000 | 0.0014 | 0.0003 | 0.0037 | 0.0024 | 0.0292 | 0.0286 | 0.0404 | 0.0329 | 0.0388 | 0.0347 | 0.0584 | 0.0583 | 0.8270 | 0.8428 | 0.0000 | 0.0006 | 0.0000 | 0.0010 | 0.0012 | 0.0003 | 0.0040 | 0.0055 | 0.0339 | 0.0372 | 0.0456 | 0.0486 | 0.0395 | 0.0466 | 0.0688 | 0.0696 | 0.8070 | 0.7905 | 0.0000 | 0.0000 | 0.0006 | 0.0038 | 0.0337 | 0.0391 | 0.0399 | 0.0609 | 0.8219 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 209 | 861 | | 543 | 4357 | 152.9 | 32.22 | 90.49 | 146.81 | 112 | 125 | 134 | 144 | 152 | 161 | 170 | 181 | 194 | 0.0925 | 403 | 1.074 | 82.81 | 25.61 | 1 | 0.3665 | 199 | 0.0040 | 21.07 | 5.680 | 0.2454 | 24410.0 | 4050000 | 697000000 | 124000000000 | 0.4295 | 0.2088 | 0.0000 | 0.0000 | 0.0029 | 0.0000 | 0.0029 | 0.0000 | 0.0632 | 0.0078 | 0.1523 | 0.0447 | 0.1638 | 0.0953 | 0.1868 | 0.0700 | 0.1782 | 0.1498 | 0.2500 | 0.6323 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0000 | 0.0000 | 0.0156 | 0.0075 | 0.0690 | 0.0413 | 0.0980 | 0.0732 | 0.0802 | 0.0450 | 0.1114 | 0.0994 | 0.6236 | 0.7336 | 0.0198 | 0.0000 | 0.0099 | 0.0000 | 0.0891 | 0.1053 | 0.1089 | 0.3684 | 0.1782 | 0.3684 | 0.1188 | 0.0526 | 0.1584 | 0.1053 | 0.1386 | 0.0000 | 0.1782 | 0.0000 | 0.0000 | 0.0075 | 0.0491 | 0.0340 | 0.1132 | 0.1208 | 0.1094 | 0.1245 | 0.4415 | 6 | 7 | 9 | 10 | 12 | 26 | 64 | 155 | 335 | 0.1505 | 5.85 | 3.608 | 0.6197 | 29737.3 | 12900000 | 6260000000 | 3270000000000 | 0.5075 | 0.1310 | 0.0714 | 0.0045 | 0.1939 | 0.0201 | 0.2041 | 0.0447 | 0.2857 | 0.1029 | 0.1276 | 0.2282 | 0.0867 | 0.2371 | 0.0255 | 0.1365 | 0.0051 | 0.1275 | 0.0000 | 0.0984 | 0.0016 | 0.0014 | 0.0008 | 0.0000 | 0.0016 | 0.0007 | 0.0195 | 0.0114 | 0.0568 | 0.0549 | 0.0860 | 0.0834 | 0.0543 | 0.0499 | 0.0933 | 0.0848 | 0.6861 | 0.7135 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0031 | 0.0145 | 0.0157 | 0.0685 | 0.0680 | 0.0858 | 0.0931 | 0.0559 | 0.0596 | 0.1022 | 0.1004 | 0.6702 | 0.6600 | 0.0009 | 0.0000 | 0.0027 | 0.0089 | 0.0608 | 0.0956 | 0.0536 | 0.0903 | 0.6872 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 559 | 397 | | 4059 | 4987 | 157.3 | 43.64 | 166.74 | 137.41 | 113 | 123 | 131 | 139 | 148 | 157 | 168 | 187 | 216 | 0.1313 | 655 | 1.114 | 90.61 | 28.23 | 1 | 0.0532 | 216 | 0.0019 | 30.80 | 6.626 | 0.2263 | 26652.8 | 4910000 | 989000000 | 219000000000 | 0.4120 | 0.2290 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0082 | 0.0005 | 0.0341 | 0.0027 | 0.0928 | 0.0269 | 0.1428 | 0.0626 | 0.1670 | 0.0541 | 0.1833 | 0.0802 | 0.3697 | 0.7729 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0039 | 0.0002 | 0.0135 | 0.0015 | 0.0410 | 0.0154 | 0.0693 | 0.0336 | 0.0738 | 0.0197 | 0.1013 | 0.0351 | 0.6956 | 0.8945 | 0.0051 | 0.0053 | 0.0064 | 0.0132 | 0.0128 | 0.0079 | 0.0370 | 0.1164 | 0.1392 | 0.1138 | 0.1520 | 0.2063 | 0.1137 | 0.1190 | 0.1494 | 0.1349 | 0.3844 | 0.2831 | 0.0006 | 0.0043 | 0.0188 | 0.0389 | 0.0832 | 0.1269 | 0.1014 | 0.1263 | 0.4997 | 31 | 49 | 69 | 94 | 126 | 164 | 210 | 272 | 369 | 0.0031 | 48.39 | 6.631 | 0.2926 | 46678.1 | 17300000 | 7530000000 | 3680000000000 | 0.5082 | 0.1638 | 0.0343 | 0.0038 | 0.1220 | 0.0131 | 0.1792 | 0.0451 | 0.1868 | 0.1264 | 0.1753 | 0.1496 | 0.1334 | 0.2034 | 0.0940 | 0.1508 | 0.0445 | 0.1189 | 0.0305 | 0.1890 | 0.0004 | 0.0007 | 0.0034 | 0.0014 | 0.0038 | 0.0031 | 0.0290 | 0.0239 | 0.0720 | 0.0560 | 0.1195 | 0.1000 | 0.0909 | 0.0796 | 0.1136 | 0.1058 | 0.5673 | 0.6295 | 0.0025 | 0.0023 | 0.0019 | 0.0023 | 0.0120 | 0.0232 | 0.0340 | 0.0518 | 0.1051 | 0.1044 | 0.1385 | 0.1353 | 0.0906 | 0.1067 | 0.1284 | 0.1276 | 0.4871 | 0.4462 | 0.0000 | 0.0061 | 0.0096 | 0.0289 | 0.0851 | 0.1327 | 0.0917 | 0.1155 | 0.5304 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 270 | 814 | | 2851 | 8407 | 391.9 | 153.08 | 40.60 | 64.74 | 211 | 237 | 264 | 302 | 359 | 440 | 510 | 564 | 609 | 0.0793 | 667 | 0.638 | 88.07 | 16.49 | 5 | 0.0831 | 237 | 0.0014 | 33.60 | 6.853 | 0.2650 | 176986.0 | 88700000 | 47600000000 | 26700000000000 | 0.3694 | 0.2467 | 0.0017 | 0.0000 | 0.0000 | 0.0018 | 0.0198 | 0.0037 | 0.0594 | 0.0117 | 0.2228 | 0.0608 | 0.2475 | 0.1148 | 0.1320 | 0.0853 | 0.1254 | 0.1160 | 0.1914 | 0.6059 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0004 | 0.0061 | 0.0056 | 0.0386 | 0.0265 | 0.0570 | 0.0521 | 0.0404 | 0.0348 | 0.0545 | 0.0465 | 0.8009 | 0.8341 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0019 | 0.0059 | 0.0049 | 0.0208 | 0.0507 | 0.0639 | 0.0789 | 0.0906 | 0.0478 | 0.0743 | 0.0741 | 0.1055 | 0.7417 | 0.6360 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0430 | 0.0675 | 0.0453 | 0.0606 | 0.7782 | 8 | 10 | 11 | 13 | 15 | 18 | 24 | 42 | 117 | 0.0814 | 2.85 | 3.639 | 0.6573 | 5839.4 | 1330000 | 353000000 | 100000000000 | 0.5410 | 0.1261 | 0.0144 | 0.0101 | 0.0804 | 0.0340 | 0.1835 | 0.0451 | 0.1773 | 0.0975 | 0.1567 | 0.1408 | 0.1649 | 0.1638 | 0.1113 | 0.1408 | 0.0804 | 0.1435 | 0.0309 | 0.2245 | 0.0015 | 0.0040 | 0.0060 | 0.0136 | 0.0144 | 0.0100 | 0.0194 | 0.0244 | 0.0557 | 0.0505 | 0.0815 | 0.0765 | 0.0532 | 0.0589 | 0.0820 | 0.0885 | 0.6864 | 0.6735 | 0.0000 | 0.0000 | 0.0013 | 0.0007 | 0.0033 | 0.0050 | 0.0196 | 0.0177 | 0.0629 | 0.0703 | 0.0812 | 0.0809 | 0.0583 | 0.0596 | 0.0799 | 0.0852 | 0.6935 | 0.6806 | 0.0034 | 0.0040 | 0.0017 | 0.0166 | 0.0625 | 0.0763 | 0.0539 | 0.0878 | 0.6936 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 886 | 459 | | 3618 | 10342 | 579.4 | 120.00 | 16.41 | 14.61 | 402 | 502 | 541 | 570 | 596 | 621 | 644 | 667 | 707 | 0.0617 | 638 | 0.872 | 72.47 | 21.02 | 4 | 0.0506 | 183 | 0.0010 | 57.19 | 7.152 | 0.1994 | 350122.0 | 218000000 | 140000000000 | 91900000000000 | 0.4429 | 0.2126 | 0.0004 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0006 | 0.0086 | 0.0012 | 0.0409 | 0.0173 | 0.0601 | 0.0352 | 0.0530 | 0.0212 | 0.0823 | 0.0391 | 0.7539 | 0.8852 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0013 | 0.0009 | 0.0167 | 0.0167 | 0.0279 | 0.0301 | 0.0196 | 0.0140 | 0.0382 | 0.0289 | 0.8963 | 0.9084 | 0.0088 | 0.0000 | 0.0044 | 0.0980 | 0.0199 | 0.0000 | 0.0508 | 0.0980 | 0.1258 | 0.1569 | 0.1523 | 0.1765 | 0.1192 | 0.0588 | 0.1501 | 0.1373 | 0.3687 | 0.2745 | 0.0000 | 0.0005 | 0.0063 | 0.0146 | 0.0466 | 0.0777 | 0.0670 | 0.0869 | 0.7005 | 6 | 8 | 9 | 11 | 13 | 15 | 17 | 20 | 29 | 0.2798 | 0.41 | 1.932 | 0.8610 | 482.7 | 28156.6 | 2820000 | 388000000 | 0.4309 | 0.2072 | 0.0435 | 0.0205 | 0.0470 | 0.0372 | 0.0509 | 0.0455 | 0.0895 | 0.0516 | 0.1126 | 0.0612 | 0.1545 | 0.0846 | 0.2073 | 0.1008 | 0.1905 | 0.1706 | 0.1043 | 0.4280 | 0.0225 | 0.0151 | 0.0206 | 0.0257 | 0.0213 | 0.0301 | 0.0324 | 0.0319 | 0.0506 | 0.0421 | 0.0689 | 0.0635 | 0.0845 | 0.0648 | 0.1386 | 0.1026 | 0.5606 | 0.6242 | 0.0382 | 0.0267 | 0.0326 | 0.0130 | 0.0336 | 0.0298 | 0.0424 | 0.0360 | 0.0559 | 0.0477 | 0.0634 | 0.0701 | 0.0662 | 0.0775 | 0.1058 | 0.0967 | 0.5620 | 0.6026 | 0.0209 | 0.0300 | 0.0386 | 0.0551 | 0.0695 | 0.0973 | 0.0921 | 0.1086 | 0.4879 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 683 | 505 | | 9600 | 13298 | 347.1 | 90.75 | 319.79 | 439.11 | 246 | 274 | 294 | 312 | 332 | 353 | 381 | 416 | 470 | 0.0782 | 1040 | 0.961 | 166.08 | 57.22 | 7 | 0.0454 | 436 | 0.0006 | 69.61 | 7.648 | 0.1494 | 128725.0 | 51000000 | 21600000000 | 9760000000000 | 0.4152 | 0.2290 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0044 | 0.0001 | 0.0190 | 0.0018 | 0.0789 | 0.0210 | 0.1597 | 0.0534 | 0.1464 | 0.0539 | 0.1647 | 0.0695 | 0.4253 | 0.8003 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0013 | 0.0000 | 0.0072 | 0.0008 | 0.0324 | 0.0123 | 0.0692 | 0.0280 | 0.0621 | 0.0217 | 0.0867 | 0.0317 | 0.7404 | 0.9055 | 0.0011 | 0.0013 | 0.0042 | 0.0116 | 0.0116 | 0.0142 | 0.0563 | 0.0927 | 0.1216 | 0.1660 | 0.1689 | 0.1789 | 0.1068 | 0.1042 | 0.1474 | 0.1416 | 0.3821 | 0.2896 | 0.0019 | 0.0036 | 0.0075 | 0.0278 | 0.0824 | 0.1264 | 0.0993 | 0.1177 | 0.5333 | 8 | 11 | 19 | 48 | 133 | 237 | 381 | 574 | 904 | 0.0562 | 65.50 | 5.773 | 0.4645 | 295068.0 | 395000000 | 660000000000 | 1.28E+15 | 0.5123 | 0.1612 | 0.0285 | 0.0008 | 0.1068 | 0.0100 | 0.2304 | 0.0455 | 0.1628 | 0.1039 | 0.1575 | 0.1882 | 0.1495 | 0.1902 | 0.0730 | 0.1302 | 0.0525 | 0.1448 | 0.0391 | 0.1865 | 0.0000 | 0.0000 | 0.0004 | 0.0007 | 0.0014 | 0.0009 | 0.0073 | 0.0049 | 0.0456 | 0.0385 | 0.0721 | 0.0610 | 0.0536 | 0.0421 | 0.0776 | 0.0731 | 0.7421 | 0.7787 | 0.0003 | 0.0009 | 0.0008 | 0.0017 | 0.0015 | 0.0020 | 0.0134 | 0.0187 | 0.0628 | 0.0715 | 0.0953 | 0.1049 | 0.0630 | 0.0729 | 0.0985 | 0.1136 | 0.6646 | 0.6137 | 0.0002 | 0.0011 | 0.0013 | 0.0095 | 0.0546 | 0.0888 | 0.0517 | 0.0893 | 0.7034 |