High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 293 | 599 | | 8522 | 18731 | 124.8 | 36.07 | 159.94 | 131.22 | 85 | 96 | 104 | 111 | 119 | 128 | 138 | 151 | 171 | 0.0579 | 1085 | 0.655 | 121.63 | 30.46 | 3 | 0.0413 | 352 | 0.0021 | 21.46 | 6.543 | 0.2583 | 16874.9 | 2480000 | 397000000 | 69100000000 | 0.4218 | 0.2248 | 0.0015 | 0.0001 | 0.0032 | 0.0001 | 0.0107 | 0.0008 | 0.0379 | 0.0042 | 0.1011 | 0.0264 | 0.1598 | 0.0609 | 0.1590 | 0.0612 | 0.1920 | 0.0880 | 0.3347 | 0.7581 | 0.0008 | 0.0001 | 0.0009 | 0.0000 | 0.0028 | 0.0005 | 0.0110 | 0.0015 | 0.0388 | 0.0136 | 0.0711 | 0.0348 | 0.0644 | 0.0249 | 0.0950 | 0.0373 | 0.7152 | 0.8874 | 0.0062 | 0.0081 | 0.0090 | 0.0161 | 0.0225 | 0.0323 | 0.0749 | 0.0833 | 0.1256 | 0.1815 | 0.1532 | 0.1505 | 0.1256 | 0.1183 | 0.1369 | 0.1465 | 0.3459 | 0.2634 | 0.0016 | 0.0021 | 0.0083 | 0.0359 | 0.0826 | 0.1188 | 0.1038 | 0.1330 | 0.5139 | 17 | 35 | 65 | 98 | 134 | 170 | 212 | 264 | 339 | 0.0080 | 16.54 | 6.041 | 0.3804 | 42799.9 | 14800000 | 6050000000 | 2820000000000 | 0.4714 | 0.1684 | 0.0176 | 0.0010 | 0.0946 | 0.0066 | 0.2089 | 0.0387 | 0.1898 | 0.0857 | 0.1697 | 0.1579 | 0.1371 | 0.1913 | 0.0887 | 0.1635 | 0.0659 | 0.1531 | 0.0277 | 0.2022 | 0.0001 | 0.0001 | 0.0011 | 0.0005 | 0.0034 | 0.0022 | 0.0141 | 0.0087 | 0.0522 | 0.0394 | 0.0960 | 0.0745 | 0.0872 | 0.0648 | 0.1214 | 0.0920 | 0.6245 | 0.7178 | 0.0011 | 0.0016 | 0.0031 | 0.0070 | 0.0130 | 0.0169 | 0.0317 | 0.0396 | 0.0907 | 0.1065 | 0.1413 | 0.1568 | 0.1106 | 0.1168 | 0.1370 | 0.1456 | 0.4715 | 0.4093 | 0.0009 | 0.0021 | 0.0059 | 0.0218 | 0.0735 | 0.1242 | 0.1046 | 0.1292 | 0.5378 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 991 | 259 | | 6417 | 8793 | 106.8 | 27.20 | 230.17 | 178.27 | 75 | 83 | 90 | 97 | 103 | 111 | 119 | 129 | 143 | 0.0945 | 831 | 1.049 | 86.61 | 32.57 | 1 | 0.0376 | 241 | 0.0029 | 14.53 | 6.155 | 0.2937 | 12146.3 | 1470000 | 189000000 | 26000000000 | 0.4126 | 0.2368 | 0.0008 | 0.0000 | 0.0025 | 0.0003 | 0.0124 | 0.0009 | 0.0395 | 0.0028 | 0.1013 | 0.0232 | 0.1836 | 0.0560 | 0.1626 | 0.0640 | 0.1775 | 0.0993 | 0.3197 | 0.7534 | 0.0006 | 0.0000 | 0.0010 | 0.0003 | 0.0037 | 0.0006 | 0.0134 | 0.0005 | 0.0424 | 0.0139 | 0.0779 | 0.0310 | 0.0647 | 0.0240 | 0.0895 | 0.0392 | 0.7067 | 0.8904 | 0.0023 | 0.0180 | 0.0054 | 0.0315 | 0.0161 | 0.0856 | 0.0889 | 0.1464 | 0.1418 | 0.1937 | 0.1916 | 0.1914 | 0.1448 | 0.0766 | 0.1402 | 0.1126 | 0.2690 | 0.1441 | 0.0020 | 0.0051 | 0.0136 | 0.0322 | 0.0770 | 0.1126 | 0.1079 | 0.1228 | 0.5268 | 22 | 53 | 93 | 153 | 208 | 257 | 312 | 379 | 480 | 0.0024 | 67.01 | 7.297 | 0.2596 | 84755.6 | 38600000 | 20300000000 | 11900000000000 | 0.5009 | 0.1509 | 0.0115 | 0.0013 | 0.0850 | 0.0111 | 0.1797 | 0.0293 | 0.1714 | 0.0723 | 0.2027 | 0.1309 | 0.1675 | 0.1982 | 0.1023 | 0.1576 | 0.0588 | 0.1709 | 0.0211 | 0.2285 | 0.0002 | 0.0000 | 0.0019 | 0.0005 | 0.0042 | 0.0025 | 0.0137 | 0.0090 | 0.0529 | 0.0395 | 0.1047 | 0.0857 | 0.0764 | 0.0623 | 0.1081 | 0.0863 | 0.6379 | 0.7142 | 0.0003 | 0.0016 | 0.0046 | 0.0049 | 0.0083 | 0.0178 | 0.0293 | 0.0348 | 0.0788 | 0.1077 | 0.1569 | 0.1814 | 0.1143 | 0.1174 | 0.1359 | 0.1344 | 0.4716 | 0.4000 | 0.0005 | 0.0023 | 0.0055 | 0.0193 | 0.0660 | 0.1225 | 0.0971 | 0.1207 | 0.5661 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 750 | 676 | | 11146 | 21855 | 106.6 | 28.30 | 189.51 | 171.91 | 74 | 83 | 90 | 97 | 103 | 110 | 118 | 128 | 143 | 0.0573 | 1252 | 0.886 | 106.10 | 29.53 | 1 | 0.0241 | 269 | 0.0014 | 32.07 | 6.896 | 0.2173 | 12166.0 | 1490000 | 200000000 | 29600000000 | 0.4458 | 0.2114 | 0.0009 | 0.0000 | 0.0026 | 0.0003 | 0.0096 | 0.0013 | 0.0300 | 0.0038 | 0.0861 | 0.0213 | 0.1508 | 0.0508 | 0.1608 | 0.0587 | 0.1819 | 0.0839 | 0.3773 | 0.7799 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0039 | 0.0003 | 0.0101 | 0.0021 | 0.0393 | 0.0133 | 0.0634 | 0.0258 | 0.0685 | 0.0231 | 0.0980 | 0.0366 | 0.7155 | 0.8988 | 0.0018 | 0.0088 | 0.0088 | 0.0164 | 0.0226 | 0.0582 | 0.0647 | 0.1239 | 0.1317 | 0.2010 | 0.1714 | 0.1795 | 0.1183 | 0.1163 | 0.1423 | 0.1277 | 0.3383 | 0.1681 | 0.0014 | 0.0032 | 0.0116 | 0.0332 | 0.0812 | 0.1162 | 0.1018 | 0.1287 | 0.5226 | 16 | 35 | 67 | 103 | 142 | 190 | 249 | 320 | 433 | 0.0120 | 37.39 | 6.296 | 0.3650 | 65463.6 | 30100000 | 16600000000 | 10400000000000 | 0.5497 | 0.1277 | 0.0358 | 0.0017 | 0.1299 | 0.0109 | 0.2197 | 0.0768 | 0.1613 | 0.1097 | 0.1616 | 0.1610 | 0.1328 | 0.1855 | 0.0738 | 0.1385 | 0.0543 | 0.1308 | 0.0308 | 0.1851 | 0.0000 | 0.0000 | 0.0012 | 0.0012 | 0.0025 | 0.0022 | 0.0135 | 0.0090 | 0.0598 | 0.0462 | 0.1069 | 0.0836 | 0.0781 | 0.0656 | 0.1195 | 0.1003 | 0.6185 | 0.6919 | 0.0006 | 0.0002 | 0.0018 | 0.0023 | 0.0045 | 0.0088 | 0.0267 | 0.0326 | 0.0915 | 0.1031 | 0.1477 | 0.1742 | 0.1100 | 0.1208 | 0.1446 | 0.1560 | 0.4726 | 0.4020 | 0.0002 | 0.0008 | 0.0031 | 0.0184 | 0.0746 | 0.1276 | 0.0976 | 0.1359 | 0.5419 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1086 | 620 | | 4452 | 3745 | 173.1 | 35.31 | 160.12 | 114.34 | 133 | 145 | 153 | 161 | 169 | 177 | 186 | 197 | 216 | 0.1522 | 570 | 1.194 | 77.34 | 28.86 | 1 | 0.0442 | 197 | 0.0021 | 21.97 | 6.469 | 0.2475 | 31225.1 | 5890000 | 1170000000 | 246000000000 | 0.3936 | 0.2497 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0053 | 0.0002 | 0.0175 | 0.0012 | 0.0519 | 0.0169 | 0.1051 | 0.0386 | 0.1236 | 0.0286 | 0.1721 | 0.0435 | 0.5232 | 0.8710 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0100 | 0.0009 | 0.0257 | 0.0133 | 0.0524 | 0.0252 | 0.0561 | 0.0137 | 0.0820 | 0.0252 | 0.7704 | 0.9216 | 0.0032 | 0.0056 | 0.0323 | 0.0113 | 0.0258 | 0.0339 | 0.0855 | 0.0734 | 0.1403 | 0.1864 | 0.1645 | 0.2034 | 0.1339 | 0.0847 | 0.1339 | 0.1073 | 0.2806 | 0.2938 | 0.0020 | 0.0039 | 0.0158 | 0.0331 | 0.0805 | 0.1051 | 0.1111 | 0.1362 | 0.5123 | 40 | 68 | 87 | 108 | 131 | 156 | 189 | 244 | 330 | 0.0027 | 39.04 | 6.449 | 0.3029 | 38710.2 | 12200000 | 4630000000 | 1970000000000 | 0.4732 | 0.1655 | 0.0072 | 0.0025 | 0.0929 | 0.0144 | 0.1158 | 0.0439 | 0.1411 | 0.0640 | 0.1496 | 0.1193 | 0.1604 | 0.1532 | 0.1086 | 0.1293 | 0.0989 | 0.1494 | 0.1255 | 0.3239 | 0.0021 | 0.0012 | 0.0031 | 0.0032 | 0.0093 | 0.0057 | 0.0260 | 0.0114 | 0.0639 | 0.0584 | 0.1070 | 0.0852 | 0.0826 | 0.0697 | 0.1158 | 0.1010 | 0.5903 | 0.6642 | 0.0027 | 0.0011 | 0.0046 | 0.0057 | 0.0146 | 0.0137 | 0.0401 | 0.0538 | 0.0866 | 0.0985 | 0.1486 | 0.1546 | 0.0902 | 0.1168 | 0.1395 | 0.1730 | 0.4731 | 0.3826 | 0.0021 | 0.0041 | 0.0110 | 0.0336 | 0.0782 | 0.1221 | 0.0912 | 0.1276 | 0.5302 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 284 | 471 | | 1555 | 4253 | 401.1 | 47.90 | 19.31 | 18.63 | 332 | 364 | 381 | 394 | 406 | 416 | 429 | 441 | 459 | 0.0997 | 424 | 1.147 | 61.20 | 22.02 | 1 | 0.1016 | 158 | 0.0027 | 20.18 | 6.139 | 0.2451 | 163138.0 | 67200000 | 28000000000 | 11800000000000 | 0.4443 | 0.1979 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0006 | 0.0285 | 0.0239 | 0.0463 | 0.0303 | 0.0484 | 0.0232 | 0.0855 | 0.0342 | 0.7877 | 0.8877 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0006 | 0.0241 | 0.0239 | 0.0345 | 0.0303 | 0.0241 | 0.0232 | 0.0427 | 0.0342 | 0.8711 | 0.8877 | 0.0426 | 0.0000 | 0.1064 | 0.0000 | 0.1064 | 0.0000 | 0.1277 | 0.0000 | 0.2340 | 0.0000 | 0.1702 | 0.0000 | 0.0638 | 0.0000 | 0.1064 | 0.0000 | 0.0426 | 0.0000 | 0.0000 | 0.0060 | 0.0072 | 0.0358 | 0.0656 | 0.1144 | 0.1085 | 0.1323 | 0.5304 | 8 | 10 | 11 | 13 | 14 | 16 | 18 | 23 | 33 | 0.2369 | 0.56 | 2.092 | 0.8275 | 719.8 | 57928.3 | 7540000 | 1230000000 | 0.5877 | 0.1129 | 0.1023 | 0.0171 | 0.1338 | 0.0274 | 0.1250 | 0.0499 | 0.1439 | 0.0846 | 0.1452 | 0.1170 | 0.1351 | 0.1471 | 0.1225 | 0.1498 | 0.0682 | 0.1619 | 0.0240 | 0.2452 | 0.0447 | 0.0107 | 0.0494 | 0.0169 | 0.0353 | 0.0331 | 0.0358 | 0.0562 | 0.0529 | 0.0841 | 0.0764 | 0.1041 | 0.0781 | 0.1013 | 0.1193 | 0.1162 | 0.5082 | 0.4774 | 0.0132 | 0.0162 | 0.0154 | 0.0310 | 0.0209 | 0.0398 | 0.0473 | 0.0516 | 0.0780 | 0.0634 | 0.0978 | 0.1165 | 0.1022 | 0.0870 | 0.1516 | 0.1608 | 0.4736 | 0.4336 | 0.0277 | 0.0317 | 0.0222 | 0.0301 | 0.0586 | 0.0705 | 0.0777 | 0.1474 | 0.5341 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 559 | 324 | | 5411 | 13979 | 127.3 | 31.31 | 130.32 | 107.34 | 89 | 100 | 109 | 117 | 124 | 132 | 141 | 151 | 168 | 0.0763 | 1067 | 1.014 | 110.37 | 33.29 | 4 | 0.0521 | 282 | 0.0023 | 18.78 | 6.376 | 0.2715 | 17190.0 | 2460000 | 372000000 | 59300000000 | 0.4432 | 0.2029 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0080 | 0.0014 | 0.0234 | 0.0043 | 0.0765 | 0.0204 | 0.1540 | 0.0553 | 0.1534 | 0.0488 | 0.1918 | 0.0784 | 0.3919 | 0.7915 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0012 | 0.0002 | 0.0077 | 0.0019 | 0.0329 | 0.0131 | 0.0659 | 0.0324 | 0.0624 | 0.0240 | 0.0845 | 0.0388 | 0.7452 | 0.8896 | 0.0068 | 0.0157 | 0.0087 | 0.0105 | 0.0243 | 0.0393 | 0.0816 | 0.0785 | 0.1516 | 0.1387 | 0.1642 | 0.2042 | 0.1127 | 0.1230 | 0.1399 | 0.1728 | 0.3100 | 0.2173 | 0.0012 | 0.0027 | 0.0054 | 0.0287 | 0.0794 | 0.1239 | 0.1084 | 0.1328 | 0.5174 | 28 | 45 | 62 | 81 | 100 | 125 | 156 | 198 | 271 | 0.0030 | 34.90 | 6.603 | 0.3130 | 28505.8 | 8880000 | 3530000000 | 1650000000000 | 0.5202 | 0.1472 | 0.0186 | 0.0011 | 0.0727 | 0.0086 | 0.1643 | 0.0338 | 0.1423 | 0.0684 | 0.1790 | 0.1246 | 0.1651 | 0.1717 | 0.1245 | 0.1441 | 0.0808 | 0.1616 | 0.0530 | 0.2861 | 0.0010 | 0.0005 | 0.0022 | 0.0019 | 0.0066 | 0.0044 | 0.0196 | 0.0131 | 0.0583 | 0.0437 | 0.1079 | 0.0808 | 0.0793 | 0.0712 | 0.1135 | 0.0987 | 0.6115 | 0.6857 | 0.0021 | 0.0027 | 0.0062 | 0.0046 | 0.0119 | 0.0161 | 0.0307 | 0.0402 | 0.0858 | 0.1010 | 0.1424 | 0.1586 | 0.1108 | 0.1077 | 0.1350 | 0.1324 | 0.4750 | 0.4367 | 0.0015 | 0.0050 | 0.0110 | 0.0224 | 0.0660 | 0.1195 | 0.1011 | 0.1256 | 0.5478 | ||
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 989 | 569 | | 11363 | 17154 | 435.1 | 102.14 | 100.15 | 106.92 | 319 | 350 | 374 | 396 | 420 | 445 | 475 | 519 | 577 | 0.0642 | 1102 | 1.214 | 111.97 | 45.88 | 1 | 0.0259 | 294 | 0.0008 | 45.10 | 7.457 | 0.1791 | 199761.0 | 96800000 | 49400000000 | 26500000000000 | 0.4356 | 0.2162 | 0.0004 | 0.0001 | 0.0023 | 0.0001 | 0.0049 | 0.0006 | 0.0187 | 0.0024 | 0.0547 | 0.0168 | 0.1228 | 0.0359 | 0.1224 | 0.0361 | 0.1532 | 0.0537 | 0.5207 | 0.8544 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0001 | 0.0074 | 0.0009 | 0.0262 | 0.0104 | 0.0589 | 0.0186 | 0.0605 | 0.0168 | 0.0788 | 0.0275 | 0.7659 | 0.9258 | 0.0027 | 0.0014 | 0.0063 | 0.0068 | 0.0094 | 0.0315 | 0.0367 | 0.0876 | 0.0823 | 0.1231 | 0.1360 | 0.1737 | 0.0922 | 0.1081 | 0.1128 | 0.1231 | 0.5217 | 0.3447 | 0.0010 | 0.0012 | 0.0068 | 0.0319 | 0.0806 | 0.1097 | 0.0930 | 0.1123 | 0.5635 | 7 | 11 | 20 | 37 | 62 | 94 | 132 | 180 | 248 | 0.0392 | 11.55 | 4.988 | 0.4732 | 21460.8 | 6340000 | 2300000000 | 971000000000 | 0.5515 | 0.1124 | 0.0581 | 0.0039 | 0.2164 | 0.0200 | 0.2885 | 0.1377 | 0.1593 | 0.1383 | 0.1259 | 0.1997 | 0.0867 | 0.1917 | 0.0344 | 0.1180 | 0.0237 | 0.1032 | 0.0070 | 0.0874 | 0.0001 | 0.0001 | 0.0005 | 0.0005 | 0.0012 | 0.0003 | 0.0130 | 0.0092 | 0.0667 | 0.0520 | 0.1087 | 0.0943 | 0.0812 | 0.0656 | 0.1186 | 0.1022 | 0.6099 | 0.6759 | 0.0005 | 0.0012 | 0.0010 | 0.0029 | 0.0045 | 0.0074 | 0.0218 | 0.0286 | 0.0939 | 0.1036 | 0.1590 | 0.1785 | 0.0997 | 0.1088 | 0.1431 | 0.1573 | 0.4763 | 0.4118 | 0.0003 | 0.0006 | 0.0018 | 0.0174 | 0.0781 | 0.1316 | 0.0944 | 0.1376 | 0.5381 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 923 | 876 | | 4650 | 27974 | 298.2 | 83.39 | 212.92 | 186.19 | 196 | 225 | 246 | 269 | 291 | 315 | 341 | 374 | 413 | 0.0507 | 1418 | 1.135 | 46.75 | 17.00 | 6 | 0.0265 | 123 | 0.0006 | 64.25 | 7.641 | 0.1408 | 95900.4 | 32900000 | 11900000000 | 4530000000000 | 0.4875 | 0.1659 | 0.0004 | 0.0000 | 0.0022 | 0.0008 | 0.0057 | 0.0008 | 0.0284 | 0.0091 | 0.1091 | 0.0467 | 0.1916 | 0.0965 | 0.1414 | 0.0657 | 0.1689 | 0.1033 | 0.3522 | 0.6771 | 0.0000 | 0.0000 | 0.0009 | 0.0007 | 0.0020 | 0.0000 | 0.0128 | 0.0059 | 0.0483 | 0.0320 | 0.0762 | 0.0692 | 0.0556 | 0.0391 | 0.0829 | 0.0608 | 0.7213 | 0.7923 | 0.0017 | 0.0048 | 0.0035 | 0.0095 | 0.0096 | 0.0263 | 0.0192 | 0.0668 | 0.0925 | 0.1265 | 0.1187 | 0.1384 | 0.0855 | 0.1289 | 0.1309 | 0.1480 | 0.5384 | 0.3508 | 0.0014 | 0.0009 | 0.0059 | 0.0237 | 0.0702 | 0.0916 | 0.0766 | 0.0861 | 0.6436 | 27 | 52 | 83 | 117 | 157 | 208 | 270 | 356 | 482 | 0.0050 | 46.50 | 6.695 | 0.3231 | 79998.9 | 40100000 | 24000000000 | 16200000000000 | 0.4940 | 0.1623 | 0.0270 | 0.0010 | 0.1183 | 0.0111 | 0.2093 | 0.0488 | 0.1802 | 0.0945 | 0.1620 | 0.1643 | 0.1329 | 0.2010 | 0.0821 | 0.1517 | 0.0530 | 0.1382 | 0.0352 | 0.1895 | 0.0007 | 0.0001 | 0.0014 | 0.0010 | 0.0042 | 0.0026 | 0.0218 | 0.0137 | 0.0642 | 0.0508 | 0.1052 | 0.0828 | 0.0816 | 0.0668 | 0.1081 | 0.0927 | 0.6129 | 0.6894 | 0.0013 | 0.0016 | 0.0028 | 0.0069 | 0.0105 | 0.0144 | 0.0378 | 0.0507 | 0.0975 | 0.1038 | 0.1384 | 0.1575 | 0.1063 | 0.1060 | 0.1287 | 0.1379 | 0.4767 | 0.4212 | 0.0009 | 0.0024 | 0.0075 | 0.0292 | 0.0795 | 0.1238 | 0.0924 | 0.1217 | 0.5426 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 324 | 442 | | 5445 | 9682 | 138.7 | 35.79 | 163.09 | 136.98 | 98 | 109 | 117 | 125 | 133 | 142 | 152 | 165 | 188 | 0.0876 | 848 | 1.068 | 95.72 | 31.26 | 1 | 0.0455 | 248 | 0.0019 | 26.13 | 6.600 | 0.2423 | 20529.1 | 3240000 | 545000000 | 97400000000 | 0.4118 | 0.2366 | 0.0003 | 0.0000 | 0.0022 | 0.0000 | 0.0119 | 0.0004 | 0.0372 | 0.0029 | 0.0985 | 0.0264 | 0.1691 | 0.0554 | 0.1649 | 0.0532 | 0.1854 | 0.0975 | 0.3304 | 0.7642 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0034 | 0.0000 | 0.0149 | 0.0009 | 0.0434 | 0.0150 | 0.0739 | 0.0264 | 0.0730 | 0.0186 | 0.1034 | 0.0390 | 0.6871 | 0.9000 | 0.0057 | 0.0136 | 0.0086 | 0.0181 | 0.0114 | 0.0317 | 0.0762 | 0.1134 | 0.1495 | 0.1950 | 0.1733 | 0.2109 | 0.1343 | 0.1293 | 0.1476 | 0.1383 | 0.2933 | 0.1497 | 0.0017 | 0.0033 | 0.0130 | 0.0401 | 0.0794 | 0.1216 | 0.1057 | 0.1358 | 0.4994 | 19 | 42 | 68 | 95 | 129 | 166 | 213 | 270 | 358 | 0.0040 | 66.08 | 6.940 | 0.2888 | 45362.2 | 16600000 | 7290000000 | 3700000000000 | 0.5293 | 0.1340 | 0.0265 | 0.0026 | 0.1297 | 0.0115 | 0.2310 | 0.0590 | 0.1394 | 0.1144 | 0.1490 | 0.1576 | 0.1355 | 0.1769 | 0.0839 | 0.1439 | 0.0606 | 0.1362 | 0.0445 | 0.1980 | 0.0006 | 0.0004 | 0.0010 | 0.0018 | 0.0023 | 0.0033 | 0.0177 | 0.0117 | 0.0586 | 0.0526 | 0.1291 | 0.0966 | 0.0780 | 0.0741 | 0.1126 | 0.0990 | 0.5999 | 0.6605 | 0.0015 | 0.0019 | 0.0018 | 0.0054 | 0.0111 | 0.0151 | 0.0348 | 0.0414 | 0.0860 | 0.1056 | 0.1631 | 0.1698 | 0.1002 | 0.0928 | 0.1236 | 0.1381 | 0.4778 | 0.4298 | 0.0010 | 0.0018 | 0.0061 | 0.0244 | 0.0786 | 0.1389 | 0.0972 | 0.1322 | 0.5198 | ||
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 489 | 834 | | 12111 | 18609 | 541.6 | 118.52 | 168.67 | 182.80 | 399 | 441 | 476 | 505 | 532 | 559 | 589 | 628 | 690 | 0.0564 | 1049 | 1.226 | 127.68 | 55.00 | 1 | 0.0283 | 343 | 0.0010 | 25.57 | 7.191 | 0.2311 | 307350.0 | 183000000 | 114000000000 | 74500000000000 | 0.4223 | 0.2210 | 0.0002 | 0.0001 | 0.0011 | 0.0003 | 0.0035 | 0.0002 | 0.0121 | 0.0018 | 0.0351 | 0.0123 | 0.0639 | 0.0223 | 0.0770 | 0.0188 | 0.1064 | 0.0282 | 0.7006 | 0.9161 | 0.0002 | 0.0000 | 0.0007 | 0.0001 | 0.0017 | 0.0002 | 0.0050 | 0.0010 | 0.0150 | 0.0084 | 0.0268 | 0.0140 | 0.0306 | 0.0093 | 0.0434 | 0.0135 | 0.8767 | 0.9536 | 0.0032 | 0.0045 | 0.0053 | 0.0061 | 0.0150 | 0.0151 | 0.0513 | 0.0363 | 0.0898 | 0.0802 | 0.1165 | 0.1104 | 0.1010 | 0.0726 | 0.1112 | 0.1104 | 0.5067 | 0.5643 | 0.0016 | 0.0023 | 0.0060 | 0.0213 | 0.0499 | 0.0789 | 0.0809 | 0.1040 | 0.6550 | 8 | 14 | 27 | 56 | 102 | 159 | 227 | 312 | 435 | 0.0253 | 65.01 | 6.264 | 0.3576 | 61863.3 | 30100000 | 17400000000 | 11500000000000 | 0.4777 | 0.1891 | 0.0835 | 0.0023 | 0.2306 | 0.0249 | 0.2838 | 0.1678 | 0.1513 | 0.1698 | 0.1153 | 0.1751 | 0.0782 | 0.1769 | 0.0402 | 0.1114 | 0.0146 | 0.0964 | 0.0026 | 0.0755 | 0.0004 | 0.0001 | 0.0000 | 0.0000 | 0.0005 | 0.0009 | 0.0147 | 0.0085 | 0.0655 | 0.0544 | 0.1197 | 0.0976 | 0.0848 | 0.0670 | 0.1186 | 0.1038 | 0.5959 | 0.6678 | 0.0000 | 0.0007 | 0.0011 | 0.0021 | 0.0057 | 0.0062 | 0.0239 | 0.0327 | 0.0959 | 0.1092 | 0.1534 | 0.1697 | 0.1026 | 0.1133 | 0.1390 | 0.1561 | 0.4782 | 0.4101 | 0.0001 | 0.0000 | 0.0024 | 0.0177 | 0.0832 | 0.1361 | 0.0944 | 0.1341 | 0.5320 | ||
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 953 | 241 | | 4452 | 16651 | 514.3 | 202.79 | 16.75 | 22.48 | 264 | 314 | 365 | 425 | 496 | 574 | 650 | 721 | 776 | 0.0610 | 1016 | 0.831 | 150.81 | 30.46 | 9 | 0.0806 | 359 | 0.0007 | 46.67 | 7.524 | 0.1977 | 305620.0 | 203000000 | 146000000000 | 112000000000000 | 0.3891 | 0.2375 | 0.0008 | 0.0022 | 0.0000 | 0.0000 | 0.0142 | 0.0022 | 0.0334 | 0.0103 | 0.0943 | 0.0357 | 0.1060 | 0.0600 | 0.1018 | 0.0527 | 0.1277 | 0.0681 | 0.5217 | 0.7688 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0015 | 0.0003 | 0.0036 | 0.0052 | 0.0259 | 0.0196 | 0.0353 | 0.0304 | 0.0230 | 0.0232 | 0.0383 | 0.0312 | 0.8724 | 0.8898 | 0.0000 | 0.0000 | 0.0000 | 0.0044 | 0.0019 | 0.0044 | 0.0045 | 0.0166 | 0.0408 | 0.0376 | 0.0388 | 0.0564 | 0.0323 | 0.0431 | 0.0511 | 0.0818 | 0.8305 | 0.7558 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0262 | 0.0419 | 0.0295 | 0.0409 | 0.8548 | 6 | 7 | 8 | 9 | 11 | 14 | 17 | 22 | 30 | 0.1712 | 0.40 | 1.575 | 0.6158 | 785.9 | 143855 | 50100000 | 21000000000 | 0.6171 | 0.0868 | 0.0605 | 0.0488 | 0.0678 | 0.0590 | 0.0946 | 0.0585 | 0.1398 | 0.0738 | 0.1565 | 0.0814 | 0.1773 | 0.0904 | 0.1603 | 0.1323 | 0.1067 | 0.1903 | 0.0365 | 0.2655 | 0.0178 | 0.0287 | 0.0157 | 0.0319 | 0.0185 | 0.0277 | 0.0267 | 0.0319 | 0.0491 | 0.0406 | 0.0697 | 0.0463 | 0.0717 | 0.0582 | 0.1168 | 0.0921 | 0.6140 | 0.6425 | 0.0160 | 0.0168 | 0.0214 | 0.0291 | 0.0295 | 0.0412 | 0.0447 | 0.0496 | 0.0736 | 0.0814 | 0.0894 | 0.0941 | 0.1054 | 0.1129 | 0.1416 | 0.1313 | 0.4783 | 0.4436 | 0.0152 | 0.0164 | 0.0269 | 0.0290 | 0.0574 | 0.0696 | 0.0884 | 0.1384 | 0.5589 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 273 | 873 | | 959 | 20054 | 113.6 | 15.41 | 28.35 | 38.32 | 95 | 99 | 103 | 107 | 113 | 117 | 121 | 127 | 135 | 0.0524 | 1050 | 1.034 | 39.40 | 13.04 | 0 | 0.1064 | 102 | 0.0763 | 0.50 | 2.832 | 0.7708 | 13136.1 | 1550000 | 186000000 | 22800000000 | 0.4056 | 0.2400 | 0.0012 | 0.0000 | 0.0036 | 0.0010 | 0.0083 | 0.0031 | 0.0154 | 0.0073 | 0.0473 | 0.0241 | 0.0746 | 0.0640 | 0.0734 | 0.0325 | 0.1006 | 0.0598 | 0.6757 | 0.8080 | 0.0011 | 0.0000 | 0.0032 | 0.0010 | 0.0076 | 0.0031 | 0.0108 | 0.0073 | 0.0314 | 0.0229 | 0.0541 | 0.0615 | 0.0400 | 0.0250 | 0.0639 | 0.0532 | 0.7879 | 0.8259 | 0.0000 | 0.0000 | 0.0127 | 0.1667 | 0.0506 | 0.0000 | 0.1013 | 0.5000 | 0.1266 | 0.3333 | 0.1392 | 0.0000 | 0.1266 | 0.0000 | 0.1266 | 0.0000 | 0.3165 | 0.0000 | 0.0022 | 0.0043 | 0.0152 | 0.0260 | 0.0390 | 0.0758 | 0.0736 | 0.1017 | 0.6623 | 11 | 13 | 15 | 17 | 20 | 22 | 26 | 31 | 40 | 0.3245 | 0.91 | 1.880 | 0.8551 | 2272.4 | 507754 | 174000000 | 71000000000 | 0.5696 | 0.1296 | 0.0433 | 0.0176 | 0.0600 | 0.0218 | 0.0785 | 0.0264 | 0.1039 | 0.0386 | 0.1265 | 0.0642 | 0.1678 | 0.0809 | 0.1887 | 0.1079 | 0.1421 | 0.1846 | 0.0893 | 0.4581 | 0.0240 | 0.0144 | 0.0282 | 0.0178 | 0.0330 | 0.0204 | 0.0353 | 0.0280 | 0.0502 | 0.0467 | 0.0618 | 0.0603 | 0.0746 | 0.0721 | 0.1061 | 0.1150 | 0.5867 | 0.6253 | 0.0284 | 0.0348 | 0.0315 | 0.0221 | 0.0495 | 0.0172 | 0.0486 | 0.0255 | 0.0769 | 0.0594 | 0.0874 | 0.0790 | 0.0867 | 0.0795 | 0.1126 | 0.1286 | 0.4784 | 0.5540 | 0.0222 | 0.0261 | 0.0286 | 0.0380 | 0.0551 | 0.0752 | 0.0968 | 0.1505 | 0.5076 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 799 | 497 | | 16816 | 24748 | 122.3 | 34.96 | 236.76 | 206.30 | 82 | 94 | 102 | 110 | 118 | 126 | 136 | 149 | 168 | 0.0650 | 1609 | 1.118 | 72.20 | 25.02 | 3 | 0.0108 | 181 | 0.0021 | 18.82 | 6.539 | 0.2763 | 16190.9 | 2320000 | 358000000 | 60000000000 | 0.4389 | 0.2098 | 0.0010 | 0.0001 | 0.0025 | 0.0003 | 0.0091 | 0.0014 | 0.0328 | 0.0040 | 0.0891 | 0.0250 | 0.1521 | 0.0565 | 0.1545 | 0.0597 | 0.1758 | 0.0901 | 0.3831 | 0.7630 | 0.0004 | 0.0001 | 0.0005 | 0.0000 | 0.0026 | 0.0002 | 0.0095 | 0.0013 | 0.0356 | 0.0130 | 0.0650 | 0.0262 | 0.0618 | 0.0238 | 0.0849 | 0.0395 | 0.7396 | 0.8959 | 0.0031 | 0.0096 | 0.0075 | 0.0071 | 0.0173 | 0.0199 | 0.0537 | 0.1065 | 0.1221 | 0.1508 | 0.1553 | 0.2060 | 0.1205 | 0.1232 | 0.1477 | 0.1521 | 0.3728 | 0.2246 | 0.0013 | 0.0031 | 0.0088 | 0.0298 | 0.0749 | 0.1135 | 0.0977 | 0.1296 | 0.5413 | 21 | 45 | 86 | 134 | 187 | 246 | 312 | 397 | 532 | 0.0053 | 78.87 | 7.190 | 0.2785 | 98609.0 | 53500000 | 34300000000 | 24800000000000 | 0.5106 | 0.1669 | 0.0256 | 0.0012 | 0.1110 | 0.0083 | 0.2322 | 0.0422 | 0.1927 | 0.1005 | 0.1604 | 0.1805 | 0.1290 | 0.2104 | 0.0825 | 0.1584 | 0.0439 | 0.1366 | 0.0227 | 0.1620 | 0.0004 | 0.0002 | 0.0009 | 0.0012 | 0.0050 | 0.0019 | 0.0154 | 0.0099 | 0.0609 | 0.0492 | 0.1064 | 0.0949 | 0.0889 | 0.0752 | 0.1192 | 0.1063 | 0.6028 | 0.6612 | 0.0004 | 0.0013 | 0.0032 | 0.0039 | 0.0100 | 0.0142 | 0.0294 | 0.0412 | 0.0896 | 0.1025 | 0.1454 | 0.1529 | 0.1084 | 0.1139 | 0.1346 | 0.1366 | 0.4791 | 0.4335 | 0.0001 | 0.0020 | 0.0079 | 0.0209 | 0.0743 | 0.1266 | 0.1001 | 0.1318 | 0.5361 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1274 | 376 | | 2281 | 2786 | 112.4 | 25.36 | 148.51 | 132.43 | 87 | 92 | 97 | 102 | 107 | 112 | 119 | 128 | 147 | 0.1637 | 456 | 1.143 | 80.71 | 26.48 | 1 | 0.0886 | 202 | 0.0048 | 13.65 | 5.717 | 0.3134 | 13272.8 | 1660000 | 220000000 | 31200000000 | 0.3671 | 0.2788 | 0.0013 | 0.0000 | 0.0019 | 0.0000 | 0.0126 | 0.0000 | 0.0265 | 0.0028 | 0.0670 | 0.0317 | 0.1062 | 0.0602 | 0.1207 | 0.0417 | 0.1903 | 0.0677 | 0.4735 | 0.7958 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0083 | 0.0000 | 0.0129 | 0.0013 | 0.0326 | 0.0193 | 0.0625 | 0.0408 | 0.0641 | 0.0171 | 0.1013 | 0.0289 | 0.7163 | 0.8926 | 0.0085 | 0.0000 | 0.0170 | 0.0176 | 0.0255 | 0.0353 | 0.0595 | 0.1000 | 0.1360 | 0.1294 | 0.1105 | 0.1471 | 0.1133 | 0.1647 | 0.1586 | 0.1353 | 0.3711 | 0.2706 | 0.0044 | 0.0065 | 0.0153 | 0.0513 | 0.0938 | 0.1134 | 0.1080 | 0.1363 | 0.4711 | 14 | 25 | 51 | 80 | 114 | 151 | 191 | 253 | 347 | 0.0074 | 29.86 | 6.106 | 0.3653 | 39586.9 | 13600000 | 5450000000 | 2400000000000 | 0.4919 | 0.1616 | 0.0228 | 0.0059 | 0.0752 | 0.0164 | 0.1686 | 0.0457 | 0.1595 | 0.0726 | 0.1800 | 0.1581 | 0.1458 | 0.1546 | 0.0911 | 0.1347 | 0.0752 | 0.1475 | 0.0820 | 0.2646 | 0.0015 | 0.0012 | 0.0044 | 0.0019 | 0.0059 | 0.0062 | 0.0236 | 0.0137 | 0.0707 | 0.0616 | 0.1216 | 0.1082 | 0.0892 | 0.0721 | 0.1054 | 0.0927 | 0.5777 | 0.6424 | 0.0033 | 0.0027 | 0.0044 | 0.0080 | 0.0142 | 0.0159 | 0.0381 | 0.0491 | 0.0817 | 0.1048 | 0.1569 | 0.1605 | 0.1122 | 0.1061 | 0.1100 | 0.1194 | 0.4793 | 0.4337 | 0.0009 | 0.0062 | 0.0133 | 0.0318 | 0.0681 | 0.1388 | 0.1149 | 0.1114 | 0.5146 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1246 | 581 | | 5724 | 10893 | 64.5 | 15.39 | 236.73 | 211.09 | 47 | 52 | 56 | 60 | 63 | 66 | 70 | 75 | 83 | 0.1007 | 1097 | 0.634 | 184.57 | 34.06 | 2 | 0.0786 | 450 | 0.0087 | 5.31 | 5.104 | 0.4181 | 4403.3 | 318930 | 24700000 | 2070000000 | 0.5293 | 0.1575 | 0.0011 | 0.0000 | 0.0029 | 0.0002 | 0.0149 | 0.0025 | 0.0344 | 0.0079 | 0.0831 | 0.0249 | 0.1403 | 0.0624 | 0.1470 | 0.0543 | 0.2027 | 0.0933 | 0.3736 | 0.7545 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0073 | 0.0014 | 0.0168 | 0.0048 | 0.0432 | 0.0173 | 0.0852 | 0.0464 | 0.0787 | 0.0324 | 0.1224 | 0.0582 | 0.6454 | 0.8396 | 0.0146 | 0.0251 | 0.0258 | 0.0282 | 0.0538 | 0.0219 | 0.0806 | 0.1066 | 0.1333 | 0.1818 | 0.1445 | 0.1630 | 0.1333 | 0.1348 | 0.1344 | 0.1285 | 0.2800 | 0.2100 | 0.0049 | 0.0125 | 0.0245 | 0.0623 | 0.1061 | 0.1303 | 0.1318 | 0.1477 | 0.3799 | 16 | 25 | 64 | 130 | 196 | 261 | 329 | 412 | 529 | 0.0116 | 86.41 | 6.934 | 0.2713 | 100595.0 | 54000000 | 33700000000 | 23600000000000 | 0.4576 | 0.1893 | 0.0320 | 0.0013 | 0.1436 | 0.0119 | 0.2339 | 0.0569 | 0.1831 | 0.1264 | 0.1737 | 0.1747 | 0.1260 | 0.2062 | 0.0652 | 0.1467 | 0.0332 | 0.1364 | 0.0094 | 0.1396 | 0.0005 | 0.0003 | 0.0027 | 0.0008 | 0.0034 | 0.0019 | 0.0151 | 0.0095 | 0.0589 | 0.0467 | 0.0943 | 0.0811 | 0.0861 | 0.0713 | 0.1289 | 0.1061 | 0.6100 | 0.6824 | 0.0003 | 0.0012 | 0.0025 | 0.0031 | 0.0076 | 0.0127 | 0.0227 | 0.0347 | 0.0882 | 0.1018 | 0.1372 | 0.1535 | 0.1175 | 0.1148 | 0.1447 | 0.1528 | 0.4794 | 0.4254 | 0.0017 | 0.0015 | 0.0040 | 0.0185 | 0.0733 | 0.1092 | 0.0968 | 0.1432 | 0.5521 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 701 | 856 | | 7996 | 17307 | 193.6 | 58.72 | 164.59 | 174.51 | 125 | 142 | 158 | 171 | 186 | 201 | 219 | 242 | 276 | 0.0699 | 1209 | 0.390 | 189.19 | 52.01 | 6 | 0.0969 | 775 | 0.0004 | 115.49 | 7.998 | 0.1188 | 40941.8 | 9380000 | 2310000000 | 607000000000 | 0.4229 | 0.2241 | 0.0005 | 0.0000 | 0.0018 | 0.0002 | 0.0094 | 0.0009 | 0.0411 | 0.0074 | 0.1168 | 0.0344 | 0.1900 | 0.0791 | 0.1790 | 0.0803 | 0.1954 | 0.1104 | 0.2659 | 0.6873 | 0.0003 | 0.0000 | 0.0010 | 0.0001 | 0.0019 | 0.0003 | 0.0127 | 0.0035 | 0.0368 | 0.0179 | 0.0736 | 0.0397 | 0.0694 | 0.0336 | 0.0989 | 0.0501 | 0.7053 | 0.8549 | 0.0011 | 0.0022 | 0.0058 | 0.0101 | 0.0132 | 0.0348 | 0.0529 | 0.0886 | 0.1242 | 0.1502 | 0.1564 | 0.1973 | 0.1036 | 0.1424 | 0.1416 | 0.1323 | 0.4012 | 0.2422 | 0.0011 | 0.0014 | 0.0067 | 0.0338 | 0.0799 | 0.1053 | 0.1028 | 0.1274 | 0.5416 | 12 | 17 | 27 | 57 | 103 | 156 | 220 | 301 | 416 | 0.0341 | 36.46 | 5.746 | 0.4218 | 57539.3 | 27000000 | 15300000000 | 10100000000000 | 0.6571 | 0.0586 | 0.0542 | 0.0031 | 0.1783 | 0.0167 | 0.2744 | 0.0940 | 0.1826 | 0.1421 | 0.1310 | 0.1851 | 0.0908 | 0.1972 | 0.0521 | 0.1171 | 0.0258 | 0.1158 | 0.0107 | 0.1290 | 0.0001 | 0.0001 | 0.0009 | 0.0003 | 0.0035 | 0.0017 | 0.0141 | 0.0100 | 0.0637 | 0.0508 | 0.1127 | 0.0947 | 0.0879 | 0.0669 | 0.1267 | 0.1070 | 0.5903 | 0.6684 | 0.0002 | 0.0012 | 0.0024 | 0.0030 | 0.0050 | 0.0089 | 0.0260 | 0.0344 | 0.0869 | 0.1000 | 0.1472 | 0.1606 | 0.1046 | 0.1172 | 0.1475 | 0.1538 | 0.4802 | 0.4209 | 0.0006 | 0.0016 | 0.0037 | 0.0192 | 0.0754 | 0.1313 | 0.0961 | 0.1295 | 0.5426 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 68 | 826 | | 4128 | 6864 | 146.8 | 44.75 | 144.31 | 126.93 | 100 | 110 | 118 | 127 | 136 | 147 | 160 | 181 | 211 | 0.1005 | 690 | 1.168 | 86.40 | 31.91 | 1 | 0.0540 | 223 | 0.0017 | 33.02 | 6.715 | 0.2229 | 23554.4 | 4140000 | 797000000 | 166000000000 | 0.3837 | 0.2702 | 0.0030 | 0.0000 | 0.0044 | 0.0000 | 0.0178 | 0.0020 | 0.0435 | 0.0054 | 0.1156 | 0.0363 | 0.1789 | 0.0632 | 0.1848 | 0.0697 | 0.1912 | 0.1133 | 0.2609 | 0.7102 | 0.0021 | 0.0000 | 0.0021 | 0.0000 | 0.0065 | 0.0008 | 0.0174 | 0.0018 | 0.0533 | 0.0206 | 0.0793 | 0.0323 | 0.0854 | 0.0354 | 0.1083 | 0.0652 | 0.6456 | 0.8440 | 0.0011 | 0.0066 | 0.0033 | 0.0087 | 0.0299 | 0.0175 | 0.0421 | 0.0611 | 0.0965 | 0.1332 | 0.1275 | 0.1681 | 0.0976 | 0.1201 | 0.1197 | 0.1638 | 0.4823 | 0.3210 | 0.0024 | 0.0042 | 0.0180 | 0.0342 | 0.0792 | 0.1104 | 0.0870 | 0.1309 | 0.5336 | 30 | 44 | 59 | 79 | 101 | 131 | 171 | 232 | 322 | 0.0037 | 48.50 | 6.480 | 0.3040 | 36934.0 | 13300000 | 5910000000 | 3030000000000 | 0.5053 | 0.1536 | 0.0289 | 0.0009 | 0.1252 | 0.0109 | 0.1753 | 0.0639 | 0.1667 | 0.0948 | 0.1830 | 0.1501 | 0.1532 | 0.1791 | 0.0886 | 0.1497 | 0.0559 | 0.1542 | 0.0231 | 0.1964 | 0.0016 | 0.0003 | 0.0026 | 0.0026 | 0.0078 | 0.0059 | 0.0260 | 0.0221 | 0.0809 | 0.0635 | 0.1135 | 0.0910 | 0.0891 | 0.0846 | 0.1135 | 0.1116 | 0.5650 | 0.6183 | 0.0020 | 0.0018 | 0.0025 | 0.0077 | 0.0088 | 0.0196 | 0.0471 | 0.0422 | 0.0972 | 0.1040 | 0.1290 | 0.1337 | 0.1035 | 0.1040 | 0.1295 | 0.1349 | 0.4804 | 0.4522 | 0.0000 | 0.0060 | 0.0116 | 0.0344 | 0.0800 | 0.1244 | 0.1000 | 0.1224 | 0.5214 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1037 | 548 | | 6893 | 19634 | 196.4 | 53.42 | 59.21 | 59.92 | 132 | 150 | 164 | 177 | 190 | 203 | 219 | 239 | 270 | 0.0562 | 1104 | 1.139 | 106.17 | 38.83 | 1 | 0.0396 | 273 | 0.0009 | 48.97 | 7.272 | 0.1760 | 41433.9 | 9350000 | 2250000000 | 573000000000 | 0.4801 | 0.1819 | 0.0008 | 0.0000 | 0.0027 | 0.0003 | 0.0176 | 0.0008 | 0.0295 | 0.0045 | 0.1140 | 0.0308 | 0.1710 | 0.0578 | 0.1497 | 0.0610 | 0.1702 | 0.0896 | 0.3445 | 0.7552 | 0.0004 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0002 | 0.0060 | 0.0012 | 0.0441 | 0.0158 | 0.0768 | 0.0292 | 0.0676 | 0.0257 | 0.1060 | 0.0467 | 0.6977 | 0.8812 | 0.0027 | 0.0063 | 0.0033 | 0.0110 | 0.0154 | 0.0267 | 0.0642 | 0.0879 | 0.1338 | 0.1586 | 0.1893 | 0.2198 | 0.1097 | 0.1224 | 0.1431 | 0.1429 | 0.3385 | 0.2245 | 0.0019 | 0.0013 | 0.0079 | 0.0282 | 0.0904 | 0.1431 | 0.1028 | 0.1352 | 0.4891 | 11 | 20 | 27 | 36 | 45 | 56 | 68 | 85 | 113 | 0.0115 | 9.46 | 5.188 | 0.4764 | 7095.4 | 1710000 | 681000000 | 349000000000 | 0.5533 | 0.1205 | 0.0095 | 0.0030 | 0.0478 | 0.0089 | 0.1372 | 0.0199 | 0.1794 | 0.0504 | 0.1937 | 0.1192 | 0.1744 | 0.1608 | 0.1277 | 0.1622 | 0.0842 | 0.1835 | 0.0462 | 0.2921 | 0.0014 | 0.0014 | 0.0025 | 0.0030 | 0.0103 | 0.0063 | 0.0254 | 0.0159 | 0.0611 | 0.0437 | 0.0923 | 0.0664 | 0.0846 | 0.0698 | 0.1181 | 0.1017 | 0.6043 | 0.6918 | 0.0040 | 0.0052 | 0.0059 | 0.0136 | 0.0158 | 0.0236 | 0.0370 | 0.0536 | 0.0902 | 0.0983 | 0.1230 | 0.1323 | 0.1097 | 0.1162 | 0.1320 | 0.1328 | 0.4824 | 0.4244 | 0.0026 | 0.0071 | 0.0163 | 0.0301 | 0.0751 | 0.0993 | 0.0984 | 0.1252 | 0.5459 | ||
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 504 | 454 | | 4632 | 9949 | 526.7 | 103.94 | 144.23 | 161.03 | 403 | 434 | 461 | 488 | 517 | 541 | 573 | 613 | 674 | 0.0767 | 763 | 1.167 | 101.13 | 34.54 | 1 | 0.0531 | 246 | 0.0009 | 55.30 | 7.231 | 0.1624 | 288245.0 | 164000000 | 96700000000 | 59100000000000 | 0.4365 | 0.2052 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0095 | 0.0004 | 0.0653 | 0.0181 | 0.1242 | 0.0349 | 0.1378 | 0.0329 | 0.1714 | 0.0511 | 0.4897 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0044 | 0.0002 | 0.0279 | 0.0136 | 0.0541 | 0.0242 | 0.0597 | 0.0141 | 0.0859 | 0.0249 | 0.7668 | 0.9230 | 0.0054 | 0.0188 | 0.0054 | 0.0125 | 0.0201 | 0.0313 | 0.0698 | 0.1438 | 0.1557 | 0.2438 | 0.1906 | 0.1750 | 0.1302 | 0.1188 | 0.1664 | 0.1563 | 0.2564 | 0.1000 | 0.0009 | 0.0038 | 0.0033 | 0.0302 | 0.0797 | 0.1282 | 0.1249 | 0.1556 | 0.4734 | 18 | 28 | 46 | 67 | 93 | 124 | 163 | 220 | 330 | 0.0156 | 19.65 | 5.459 | 0.4608 | 46729.0 | 24700000 | 17300000000 | 14400000000000 | 0.5530 | 0.1302 | 0.0176 | 0.0010 | 0.1067 | 0.0100 | 0.2360 | 0.0424 | 0.1854 | 0.0883 | 0.1601 | 0.1621 | 0.1292 | 0.2014 | 0.0730 | 0.1717 | 0.0597 | 0.1438 | 0.0323 | 0.1793 | 0.0002 | 0.0000 | 0.0009 | 0.0012 | 0.0024 | 0.0019 | 0.0176 | 0.0129 | 0.0691 | 0.0574 | 0.1203 | 0.0945 | 0.0888 | 0.0781 | 0.1108 | 0.1107 | 0.5899 | 0.6432 | 0.0004 | 0.0009 | 0.0011 | 0.0022 | 0.0061 | 0.0106 | 0.0301 | 0.0396 | 0.1050 | 0.1091 | 0.1384 | 0.1552 | 0.0986 | 0.0994 | 0.1376 | 0.1271 | 0.4828 | 0.4560 | 0.0017 | 0.0012 | 0.0043 | 0.0240 | 0.0822 | 0.1343 | 0.0909 | 0.1308 | 0.5305 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1109 | 791 | | 9893 | 20116 | 97.3 | 34.99 | 152.25 | 139.00 | 59 | 71 | 78 | 85 | 92 | 100 | 109 | 122 | 142 | 0.0680 | 1367 | 0.691 | 64.66 | 21.00 | 2 | 0.0208 | 206 | 0.0011 | 48.57 | 7.180 | 0.2021 | 10687.4 | 1320000 | 184000000 | 28700000000 | 0.5283 | 0.1408 | 0.0017 | 0.0000 | 0.0030 | 0.0003 | 0.0286 | 0.0013 | 0.0650 | 0.0096 | 0.1374 | 0.0448 | 0.1825 | 0.0976 | 0.1668 | 0.0904 | 0.1696 | 0.1321 | 0.2454 | 0.6238 | 0.0009 | 0.0000 | 0.0010 | 0.0001 | 0.0048 | 0.0001 | 0.0158 | 0.0049 | 0.0504 | 0.0240 | 0.0807 | 0.0492 | 0.0728 | 0.0375 | 0.1094 | 0.0633 | 0.6642 | 0.8209 | 0.0008 | 0.0032 | 0.0055 | 0.0144 | 0.0152 | 0.0335 | 0.0601 | 0.0813 | 0.1261 | 0.1491 | 0.1582 | 0.1914 | 0.1290 | 0.1148 | 0.1472 | 0.1260 | 0.3579 | 0.2863 | 0.0016 | 0.0025 | 0.0094 | 0.0338 | 0.0912 | 0.1218 | 0.1065 | 0.1342 | 0.4990 | 16 | 34 | 57 | 83 | 111 | 147 | 192 | 251 | 344 | 0.0118 | 24.15 | 5.952 | 0.3916 | 42501.1 | 16300000 | 7740000000 | 4260000000000 | 0.4988 | 0.1607 | 0.0275 | 0.0011 | 0.1169 | 0.0097 | 0.2130 | 0.0538 | 0.1636 | 0.0856 | 0.1683 | 0.1643 | 0.1424 | 0.1882 | 0.0820 | 0.1427 | 0.0568 | 0.1438 | 0.0296 | 0.2107 | 0.0004 | 0.0003 | 0.0017 | 0.0007 | 0.0039 | 0.0041 | 0.0160 | 0.0085 | 0.0595 | 0.0462 | 0.1060 | 0.0850 | 0.0867 | 0.0678 | 0.1130 | 0.1003 | 0.6127 | 0.6871 | 0.0008 | 0.0017 | 0.0031 | 0.0057 | 0.0093 | 0.0109 | 0.0287 | 0.0382 | 0.0867 | 0.1002 | 0.1526 | 0.1644 | 0.1028 | 0.1095 | 0.1329 | 0.1367 | 0.4830 | 0.4326 | 0.0001 | 0.0023 | 0.0070 | 0.0206 | 0.0702 | 0.1325 | 0.0932 | 0.1236 | 0.5506 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 373 | 297 | | 8100 | 26881 | 413.8 | 80.21 | 134.66 | 112.18 | 311 | 343 | 368 | 389 | 410 | 432 | 457 | 483 | 520 | 0.0428 | 1150 | 1.063 | 121.84 | 35.38 | 1 | 0.0363 | 294 | 0.0012 | 29.87 | 6.930 | 0.2112 | 177657.0 | 78900000 | 36200000000 | 17100000000000 | 0.4441 | 0.2061 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0031 | 0.0001 | 0.0127 | 0.0006 | 0.0529 | 0.0119 | 0.1206 | 0.0278 | 0.1395 | 0.0227 | 0.1558 | 0.0414 | 0.5151 | 0.8954 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0038 | 0.0005 | 0.0215 | 0.0096 | 0.0486 | 0.0211 | 0.0558 | 0.0122 | 0.0700 | 0.0216 | 0.7987 | 0.9350 | 0.0038 | 0.0471 | 0.0045 | 0.0059 | 0.0257 | 0.0941 | 0.0863 | 0.1588 | 0.1529 | 0.1412 | 0.2044 | 0.2118 | 0.1317 | 0.0647 | 0.1363 | 0.0706 | 0.2544 | 0.2059 | 0.0005 | 0.0013 | 0.0066 | 0.0247 | 0.0683 | 0.1268 | 0.1056 | 0.1298 | 0.5363 | 27 | 46 | 66 | 85 | 107 | 130 | 159 | 200 | 272 | 0.0091 | 10.68 | 5.490 | 0.4380 | 30717.4 | 10300000 | 4530000000 | 2410000000000 | 0.4651 | 0.1879 | 0.0107 | 0.0010 | 0.0569 | 0.0033 | 0.1502 | 0.0207 | 0.1620 | 0.0586 | 0.1808 | 0.1345 | 0.1705 | 0.1748 | 0.1171 | 0.1516 | 0.0871 | 0.1645 | 0.0646 | 0.2909 | 0.0008 | 0.0005 | 0.0020 | 0.0009 | 0.0061 | 0.0038 | 0.0179 | 0.0117 | 0.0589 | 0.0446 | 0.1034 | 0.0774 | 0.0837 | 0.0680 | 0.1176 | 0.1006 | 0.6097 | 0.6925 | 0.0016 | 0.0022 | 0.0055 | 0.0050 | 0.0095 | 0.0162 | 0.0356 | 0.0429 | 0.0832 | 0.1003 | 0.1356 | 0.1457 | 0.1111 | 0.1195 | 0.1349 | 0.1425 | 0.4830 | 0.4257 | 0.0007 | 0.0045 | 0.0076 | 0.0250 | 0.0755 | 0.1170 | 0.0983 | 0.1280 | 0.5435 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 764 | 363 | | 6534 | 17604 | 111.7 | 25.73 | 145.88 | 126.49 | 83 | 92 | 97 | 103 | 108 | 114 | 120 | 129 | 143 | 0.0564 | 993 | 1.124 | 94.02 | 35.78 | 1 | 0.0376 | 246 | 0.0034 | 14.04 | 6.028 | 0.2979 | 13134.9 | 1640000 | 217000000 | 30900000000 | 0.4275 | 0.2230 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0075 | 0.0010 | 0.0183 | 0.0028 | 0.0649 | 0.0170 | 0.1122 | 0.0403 | 0.1486 | 0.0380 | 0.1796 | 0.0591 | 0.4674 | 0.8418 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0028 | 0.0000 | 0.0079 | 0.0003 | 0.0333 | 0.0128 | 0.0545 | 0.0232 | 0.0712 | 0.0172 | 0.0935 | 0.0318 | 0.7365 | 0.9147 | 0.0071 | 0.0174 | 0.0202 | 0.0174 | 0.0333 | 0.0378 | 0.0787 | 0.0930 | 0.1403 | 0.1715 | 0.1675 | 0.2151 | 0.1120 | 0.0959 | 0.1534 | 0.1163 | 0.2876 | 0.2355 | 0.0028 | 0.0083 | 0.0160 | 0.0333 | 0.0850 | 0.1273 | 0.1197 | 0.1377 | 0.4700 | 21 | 39 | 60 | 85 | 114 | 147 | 184 | 233 | 308 | 0.0032 | 38.65 | 6.813 | 0.3067 | 37278.1 | 13400000 | 6170000000 | 3410000000000 | 0.5292 | 0.1463 | 0.0158 | 0.0007 | 0.0848 | 0.0055 | 0.1961 | 0.0342 | 0.1492 | 0.0782 | 0.1694 | 0.1525 | 0.1634 | 0.1913 | 0.1004 | 0.1376 | 0.0710 | 0.1535 | 0.0499 | 0.2464 | 0.0006 | 0.0002 | 0.0008 | 0.0006 | 0.0028 | 0.0019 | 0.0142 | 0.0107 | 0.0533 | 0.0454 | 0.0994 | 0.0759 | 0.0817 | 0.0681 | 0.1120 | 0.0951 | 0.6354 | 0.7021 | 0.0009 | 0.0016 | 0.0027 | 0.0029 | 0.0108 | 0.0144 | 0.0315 | 0.0406 | 0.0887 | 0.1021 | 0.1392 | 0.1515 | 0.1106 | 0.1145 | 0.1317 | 0.1242 | 0.4840 | 0.4482 | 0.0004 | 0.0023 | 0.0046 | 0.0198 | 0.0710 | 0.1242 | 0.0992 | 0.1273 | 0.5511 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 600 | | 4616 | 7928 | 344.2 | 66.06 | 265.90 | 254.61 | 259 | 286 | 308 | 325 | 341 | 359 | 377 | 401 | 435 | 0.1043 | 827 | 1.180 | 138.18 | 54.34 | 1 | 0.0782 | 361 | 0.0012 | 25.73 | 6.964 | 0.2269 | 122856.0 | 45400000 | 17300000000 | 6770000000000 | 0.4140 | 0.2347 | 0.0009 | 0.0000 | 0.0025 | 0.0002 | 0.0041 | 0.0002 | 0.0173 | 0.0013 | 0.0447 | 0.0183 | 0.0676 | 0.0359 | 0.0711 | 0.0219 | 0.1101 | 0.0415 | 0.6818 | 0.8807 | 0.0005 | 0.0000 | 0.0015 | 0.0000 | 0.0020 | 0.0000 | 0.0077 | 0.0007 | 0.0197 | 0.0159 | 0.0277 | 0.0303 | 0.0289 | 0.0135 | 0.0451 | 0.0266 | 0.8668 | 0.9131 | 0.0028 | 0.0000 | 0.0041 | 0.0000 | 0.0180 | 0.0000 | 0.0511 | 0.0000 | 0.0898 | 0.0000 | 0.1367 | 0.0000 | 0.1450 | 0.0000 | 0.1257 | 0.0000 | 0.4268 | 0.0000 | 0.0013 | 0.0031 | 0.0071 | 0.0205 | 0.0361 | 0.0672 | 0.0828 | 0.1033 | 0.6785 | 30 | 47 | 84 | 143 | 199 | 254 | 331 | 426 | 605 | 0.0066 | 47.91 | 6.596 | 0.3097 | 135523.0 | 96800000 | 84600000000 | 83800000000000 | 0.5314 | 0.1336 | 0.0148 | 0.0008 | 0.0818 | 0.0076 | 0.2167 | 0.0239 | 0.1528 | 0.0725 | 0.1730 | 0.1457 | 0.1302 | 0.1803 | 0.1005 | 0.1489 | 0.0733 | 0.1636 | 0.0569 | 0.2568 | 0.0000 | 0.0000 | 0.0011 | 0.0007 | 0.0061 | 0.0013 | 0.0143 | 0.0088 | 0.0586 | 0.0424 | 0.1040 | 0.0805 | 0.0828 | 0.0621 | 0.1157 | 0.0988 | 0.6175 | 0.7053 | 0.0008 | 0.0010 | 0.0016 | 0.0075 | 0.0076 | 0.0139 | 0.0298 | 0.0378 | 0.0953 | 0.0925 | 0.1460 | 0.1492 | 0.0973 | 0.1089 | 0.1375 | 0.1318 | 0.4841 | 0.4575 | 0.0003 | 0.0016 | 0.0046 | 0.0178 | 0.0753 | 0.1358 | 0.0976 | 0.1289 | 0.5381 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 674 | 423 | | 2494 | 12270 | 100.8 | 25.07 | 240.02 | 220.97 | 70 | 79 | 87 | 94 | 100 | 105 | 112 | 120 | 134 | 0.0824 | 1011 | 0.313 | 186.85 | 42.64 | 3 | 0.3091 | 771 | 0.0033 | 14.33 | 5.992 | 0.3037 | 10783.5 | 1220000 | 145000000 | 18200000000 | 0.4342 | 0.2159 | 0.0007 | 0.0000 | 0.0034 | 0.0000 | 0.0189 | 0.0009 | 0.0444 | 0.0076 | 0.1098 | 0.0438 | 0.1825 | 0.0795 | 0.1589 | 0.0831 | 0.1845 | 0.1273 | 0.2970 | 0.6577 | 0.0005 | 0.0000 | 0.0015 | 0.0000 | 0.0056 | 0.0004 | 0.0153 | 0.0054 | 0.0490 | 0.0321 | 0.0842 | 0.0534 | 0.0745 | 0.0434 | 0.0990 | 0.0671 | 0.6704 | 0.7982 | 0.0042 | 0.0062 | 0.0253 | 0.0186 | 0.0547 | 0.1056 | 0.0674 | 0.1801 | 0.1558 | 0.1988 | 0.1853 | 0.1801 | 0.1137 | 0.1242 | 0.1726 | 0.1056 | 0.2211 | 0.0807 | 0.0025 | 0.0050 | 0.0091 | 0.0380 | 0.0809 | 0.1353 | 0.1089 | 0.1601 | 0.4604 | 20 | 40 | 82 | 132 | 185 | 240 | 304 | 392 | 551 | 0.0090 | 45.80 | 6.615 | 0.3329 | 106431.0 | 63700000 | 46200000000 | 38100000000000 | 0.5619 | 0.1212 | 0.0208 | 0.0008 | 0.1223 | 0.0067 | 0.2152 | 0.0569 | 0.1437 | 0.0937 | 0.1675 | 0.1632 | 0.1477 | 0.2010 | 0.0898 | 0.1402 | 0.0589 | 0.1320 | 0.0340 | 0.2056 | 0.0003 | 0.0000 | 0.0013 | 0.0004 | 0.0035 | 0.0018 | 0.0145 | 0.0100 | 0.0650 | 0.0520 | 0.1181 | 0.0946 | 0.0828 | 0.0744 | 0.1196 | 0.1048 | 0.5949 | 0.6619 | 0.0007 | 0.0025 | 0.0030 | 0.0053 | 0.0117 | 0.0171 | 0.0319 | 0.0421 | 0.0986 | 0.1075 | 0.1463 | 0.1430 | 0.1003 | 0.0888 | 0.1232 | 0.1174 | 0.4843 | 0.4763 | 0.0010 | 0.0010 | 0.0057 | 0.0267 | 0.0786 | 0.1316 | 0.0970 | 0.1210 | 0.5374 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 381 | 145 | | 5192 | 12222 | 121.8 | 35.24 | 138.67 | 114.15 | 83 | 94 | 102 | 110 | 116 | 124 | 133 | 144 | 164 | 0.0965 | 1179 | 1.132 | 100.81 | 39.70 | 1 | 0.0516 | 268 | 0.0022 | 24.43 | 6.447 | 0.2469 | 16073.7 | 2320000 | 371000000 | 66000000000 | 0.4315 | 0.2137 | 0.0010 | 0.0000 | 0.0030 | 0.0007 | 0.0090 | 0.0011 | 0.0373 | 0.0037 | 0.0959 | 0.0307 | 0.1588 | 0.0609 | 0.1652 | 0.0620 | 0.1851 | 0.0955 | 0.3447 | 0.7455 | 0.0003 | 0.0000 | 0.0008 | 0.0002 | 0.0035 | 0.0008 | 0.0124 | 0.0022 | 0.0427 | 0.0179 | 0.0773 | 0.0373 | 0.0780 | 0.0291 | 0.1065 | 0.0474 | 0.6786 | 0.8651 | 0.0084 | 0.0169 | 0.0115 | 0.0217 | 0.0282 | 0.0241 | 0.0720 | 0.0964 | 0.1493 | 0.1831 | 0.1879 | 0.1735 | 0.1075 | 0.1108 | 0.1253 | 0.1181 | 0.3100 | 0.2554 | 0.0018 | 0.0071 | 0.0143 | 0.0442 | 0.1000 | 0.1420 | 0.1210 | 0.1353 | 0.4341 | 27 | 44 | 62 | 82 | 105 | 136 | 174 | 220 | 294 | 0.0026 | 46.29 | 6.781 | 0.2926 | 32257.1 | 10200000 | 3940000000 | 1760000000000 | 0.5055 | 0.1484 | 0.0285 | 0.0012 | 0.1160 | 0.0094 | 0.1792 | 0.0374 | 0.1845 | 0.0951 | 0.1492 | 0.1547 | 0.1481 | 0.1868 | 0.0912 | 0.1503 | 0.0580 | 0.1503 | 0.0453 | 0.2148 | 0.0007 | 0.0001 | 0.0028 | 0.0026 | 0.0047 | 0.0039 | 0.0200 | 0.0169 | 0.0617 | 0.0500 | 0.1072 | 0.0842 | 0.0897 | 0.0737 | 0.1141 | 0.1065 | 0.5992 | 0.6620 | 0.0010 | 0.0023 | 0.0033 | 0.0101 | 0.0123 | 0.0192 | 0.0327 | 0.0504 | 0.0939 | 0.1018 | 0.1401 | 0.1499 | 0.1034 | 0.1093 | 0.1273 | 0.1340 | 0.4860 | 0.4231 | 0.0013 | 0.0019 | 0.0073 | 0.0240 | 0.0788 | 0.1222 | 0.0988 | 0.1259 | 0.5398 |