High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 781 | 933 | | 4650 | 7671 | 149.2 | 35.80 | 272.55 | 157.57 | 110 | 120 | 127 | 134 | 142 | 151 | 162 | 176 | 198 | 0.0948 | 727 | 1.075 | 97.75 | 27.80 | 1 | 0.0520 | 242 | 0.0020 | 26.81 | 6.558 | 0.2363 | 23531.1 | 3940000 | 699000000 | 132000000000 | 0.4493 | 0.1999 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0104 | 0.0002 | 0.0338 | 0.0009 | 0.0898 | 0.0243 | 0.1628 | 0.0471 | 0.1597 | 0.0468 | 0.1837 | 0.0695 | 0.3577 | 0.8111 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0002 | 0.0118 | 0.0004 | 0.0454 | 0.0150 | 0.0668 | 0.0232 | 0.0778 | 0.0163 | 0.1088 | 0.0306 | 0.6864 | 0.9142 | 0.0023 | 0.0030 | 0.0092 | 0.0060 | 0.0358 | 0.0329 | 0.0796 | 0.0928 | 0.1476 | 0.1707 | 0.1857 | 0.2335 | 0.1153 | 0.1138 | 0.1361 | 0.1707 | 0.2884 | 0.1766 | 0.0020 | 0.0035 | 0.0111 | 0.0308 | 0.0968 | 0.1402 | 0.1160 | 0.1452 | 0.4544 | 91 | 134 | 171 | 208 | 247 | 291 | 338 | 395 | 486 | 0.0007 | 96.75 | 7.538 | 0.1758 | 99105.9 | 44100000 | 22800000000 | 13300000000000 | 0.5485 | 0.1214 | 0.0151 | 0.0008 | 0.0764 | 0.0058 | 0.1871 | 0.0233 | 0.1861 | 0.0595 | 0.2027 | 0.1375 | 0.1554 | 0.2135 | 0.0941 | 0.1857 | 0.0520 | 0.1666 | 0.0312 | 0.2074 | 0.0009 | 0.0002 | 0.0030 | 0.0007 | 0.0077 | 0.0036 | 0.0219 | 0.0100 | 0.0743 | 0.0552 | 0.1272 | 0.1019 | 0.1078 | 0.0886 | 0.1429 | 0.1166 | 0.5144 | 0.6232 | 0.0008 | 0.0053 | 0.0106 | 0.0148 | 0.0203 | 0.0373 | 0.0519 | 0.0841 | 0.1339 | 0.1587 | 0.1729 | 0.1829 | 0.1303 | 0.1533 | 0.1652 | 0.1385 | 0.3141 | 0.2250 | 0.0009 | 0.0051 | 0.0146 | 0.0363 | 0.0991 | 0.1479 | 0.1303 | 0.1511 | 0.4148 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 525 | 784 | | 306 | 3162 | 64.0 | 11.66 | 117.65 | 178.73 | 49 | 52 | 58 | 61 | 64 | 67 | 70 | 74 | 79 | 0.1395 | 441 | 1.153 | 68.73 | 23.77 | 1 | 0.5556 | 170 | 0.0077 | 10.17 | 5.047 | 0.3110 | 4226.0 | 287862 | 20200000 | 1450000000 | 0.4562 | 0.1761 | 0.0000 | 0.0000 | 0.0147 | 0.0033 | 0.0196 | 0.0000 | 0.0686 | 0.0133 | 0.1520 | 0.0365 | 0.1765 | 0.1794 | 0.1520 | 0.0332 | 0.1912 | 0.1296 | 0.2255 | 0.6047 | 0.0000 | 0.0000 | 0.0118 | 0.0033 | 0.0039 | 0.0000 | 0.0433 | 0.0131 | 0.0630 | 0.0359 | 0.1299 | 0.1634 | 0.0591 | 0.0327 | 0.1378 | 0.0882 | 0.5512 | 0.6634 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0800 | 0.0000 | 0.0600 | 0.8000 | 0.2200 | 0.2000 | 0.2000 | 0.0000 | 0.1400 | 0.0000 | 0.1400 | 0.0000 | 0.1200 | 0.0000 | 0.0062 | 0.0124 | 0.0248 | 0.0559 | 0.1242 | 0.0994 | 0.1242 | 0.1180 | 0.4348 | 11 | 12 | 13 | 15 | 18 | 44 | 106 | 220 | 400 | 0.1851 | 37.34 | 4.002 | 0.6018 | 45776.0 | 25200000 | 16900000000 | 13200000000000 | 0.6720 | 0.0567 | 0.1282 | 0.0081 | 0.1949 | 0.0782 | 0.2513 | 0.1240 | 0.1179 | 0.1563 | 0.1128 | 0.1725 | 0.0667 | 0.1590 | 0.0359 | 0.0755 | 0.0359 | 0.0916 | 0.0564 | 0.1348 | 0.0010 | 0.0000 | 0.0010 | 0.0009 | 0.0040 | 0.0027 | 0.0210 | 0.0153 | 0.0791 | 0.0694 | 0.1351 | 0.1127 | 0.1011 | 0.0902 | 0.1592 | 0.1461 | 0.4985 | 0.5627 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0012 | 0.0054 | 0.0348 | 0.0312 | 0.1057 | 0.1098 | 0.1480 | 0.1707 | 0.1294 | 0.1328 | 0.1654 | 0.1667 | 0.4142 | 0.3821 | 0.0011 | 0.0000 | 0.0033 | 0.0255 | 0.0909 | 0.1408 | 0.1098 | 0.1663 | 0.4623 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 602 | 376 | | 1156 | 4064 | 474.2 | 143.37 | 10.35 | 8.30 | 315 | 334 | 360 | 391 | 431 | 490 | 562 | 644 | 697 | 0.0947 | 385 | 1.114 | 51.86 | 18.44 | 1 | 0.1211 | 140 | 0.0033 | 11.41 | 6.019 | 0.2906 | 245360.0 | 137000000 | 81700000000 | 51000000000000 | 0.3632 | 0.2648 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0025 | 0.0010 | 0.0327 | 0.0031 | 0.0955 | 0.0462 | 0.1382 | 0.0776 | 0.1709 | 0.0525 | 0.1608 | 0.0860 | 0.3995 | 0.7324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0009 | 0.0136 | 0.0017 | 0.0339 | 0.0304 | 0.0434 | 0.0470 | 0.0542 | 0.0261 | 0.0488 | 0.0487 | 0.8049 | 0.8452 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0118 | 0.0152 | 0.0559 | 0.0812 | 0.0588 | 0.0812 | 0.0559 | 0.0558 | 0.0765 | 0.1269 | 0.7412 | 0.6396 | 0.0000 | 0.0000 | 0.0000 | 0.0041 | 0.0412 | 0.0741 | 0.0329 | 0.0658 | 0.7819 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 15 | 0.0098 | 16.68 | 5.103 | 0.3379 | 176.1 | 6409.85 | 409709 | 33400000 | 0.4040 | 0.2136 | 0.0440 | 0.0038 | 0.1040 | 0.0105 | 0.1253 | 0.0332 | 0.2015 | 0.0514 | 0.2154 | 0.0867 | 0.1685 | 0.1160 | 0.1026 | 0.1499 | 0.0330 | 0.2376 | 0.0059 | 0.3110 | 0.0174 | 0.0014 | 0.0349 | 0.0052 | 0.0418 | 0.0193 | 0.0499 | 0.0293 | 0.0774 | 0.0503 | 0.1078 | 0.0748 | 0.1139 | 0.0871 | 0.1390 | 0.1550 | 0.4179 | 0.5775 | 0.0490 | 0.0472 | 0.0672 | 0.0407 | 0.0608 | 0.0650 | 0.0572 | 0.0911 | 0.0762 | 0.1382 | 0.1016 | 0.1154 | 0.1143 | 0.1073 | 0.1661 | 0.1268 | 0.3076 | 0.2683 | 0.0357 | 0.0421 | 0.0562 | 0.0761 | 0.0860 | 0.1094 | 0.1018 | 0.1281 | 0.3645 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1162 | 503 | | 2529 | 2344 | 126.3 | 43.34 | 188.90 | 122.03 | 73 | 88 | 100 | 110 | 122 | 133 | 145 | 162 | 185 | 0.1950 | 457 | 0.720 | 84.38 | 20.03 | 1 | 0.0834 | 211 | 0.0009 | 89.32 | 7.225 | 0.1409 | 17828.9 | 2770000 | 469000000 | 85100000000 | 0.4531 | 0.1879 | 0.0000 | 0.0000 | 0.0045 | 0.0021 | 0.0334 | 0.0032 | 0.0885 | 0.0117 | 0.1554 | 0.0573 | 0.2069 | 0.1183 | 0.1527 | 0.1210 | 0.1509 | 0.1666 | 0.2078 | 0.5199 | 0.0000 | 0.0000 | 0.0006 | 0.0013 | 0.0023 | 0.0018 | 0.0153 | 0.0081 | 0.0512 | 0.0346 | 0.0904 | 0.0606 | 0.0745 | 0.0454 | 0.0944 | 0.0718 | 0.6714 | 0.7764 | 0.0031 | 0.0088 | 0.0077 | 0.0263 | 0.0153 | 0.0351 | 0.0537 | 0.0906 | 0.1503 | 0.1579 | 0.1656 | 0.1813 | 0.1012 | 0.0906 | 0.1518 | 0.1579 | 0.3512 | 0.2515 | 0.0000 | 0.0009 | 0.0043 | 0.0282 | 0.1059 | 0.1443 | 0.1059 | 0.1460 | 0.4646 | 57 | 75 | 104 | 135 | 169 | 201 | 239 | 281 | 355 | 0.0049 | 19.35 | 5.900 | 0.3617 | 50569.7 | 17000000 | 6670000000 | 2960000000000 | 0.5121 | 0.1476 | 0.0119 | 0.0010 | 0.0889 | 0.0089 | 0.1976 | 0.0207 | 0.1621 | 0.0720 | 0.1581 | 0.1519 | 0.1561 | 0.2002 | 0.0870 | 0.1322 | 0.0870 | 0.1686 | 0.0514 | 0.2446 | 0.0000 | 0.0006 | 0.0008 | 0.0006 | 0.0093 | 0.0025 | 0.0202 | 0.0153 | 0.0644 | 0.0567 | 0.1149 | 0.0943 | 0.0901 | 0.0732 | 0.1335 | 0.1115 | 0.5668 | 0.6452 | 0.0013 | 0.0090 | 0.0064 | 0.0162 | 0.0153 | 0.0252 | 0.0435 | 0.0629 | 0.1228 | 0.1457 | 0.1662 | 0.1853 | 0.1368 | 0.1097 | 0.1675 | 0.1583 | 0.3402 | 0.2878 | 0.0000 | 0.0019 | 0.0135 | 0.0348 | 0.0890 | 0.1277 | 0.1180 | 0.1750 | 0.4400 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 917 | 765 | | 4787 | 6025 | 134.0 | 29.36 | 199.47 | 144.31 | 101 | 111 | 117 | 124 | 130 | 137 | 145 | 154 | 168 | 0.1200 | 723 | 1.159 | 112.49 | 39.01 | 1 | 0.0570 | 273 | 0.0026 | 20.01 | 6.253 | 0.2547 | 18810.6 | 2780000 | 434000000 | 72000000000 | 0.4427 | 0.2093 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0064 | 0.0013 | 0.0155 | 0.0016 | 0.0709 | 0.0202 | 0.1267 | 0.0377 | 0.1506 | 0.0388 | 0.1815 | 0.0566 | 0.4467 | 0.8438 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0073 | 0.0004 | 0.0405 | 0.0149 | 0.0653 | 0.0246 | 0.0710 | 0.0181 | 0.0965 | 0.0305 | 0.7169 | 0.9114 | 0.0043 | 0.0000 | 0.0157 | 0.0082 | 0.0443 | 0.0286 | 0.0944 | 0.1224 | 0.1688 | 0.1510 | 0.1574 | 0.2041 | 0.0987 | 0.1102 | 0.1273 | 0.1224 | 0.2890 | 0.2531 | 0.0018 | 0.0042 | 0.0125 | 0.0365 | 0.0983 | 0.1347 | 0.1117 | 0.1440 | 0.4564 | 44 | 68 | 100 | 134 | 171 | 211 | 256 | 309 | 392 | 0.0015 | 70.67 | 7.066 | 0.2195 | 60610.6 | 23900000 | 11300000000 | 6160000000000 | 0.5305 | 0.1272 | 0.0202 | 0.0004 | 0.0960 | 0.0047 | 0.2098 | 0.0436 | 0.2030 | 0.0781 | 0.1955 | 0.1872 | 0.1348 | 0.1919 | 0.0851 | 0.1725 | 0.0447 | 0.1552 | 0.0110 | 0.1665 | 0.0006 | 0.0003 | 0.0009 | 0.0005 | 0.0019 | 0.0026 | 0.0206 | 0.0127 | 0.0768 | 0.0560 | 0.1070 | 0.0915 | 0.0989 | 0.0710 | 0.1385 | 0.1099 | 0.5548 | 0.6556 | 0.0015 | 0.0032 | 0.0064 | 0.0097 | 0.0124 | 0.0175 | 0.0500 | 0.0662 | 0.1199 | 0.1364 | 0.1640 | 0.1857 | 0.1189 | 0.1422 | 0.1690 | 0.1513 | 0.3578 | 0.2877 | 0.0008 | 0.0008 | 0.0077 | 0.0291 | 0.0926 | 0.1403 | 0.1170 | 0.1592 | 0.4525 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 118 | 70 | | 1754 | 4174 | 82.7 | 19.21 | 183.51 | 192.01 | 60 | 66 | 71 | 76 | 81 | 86 | 92 | 98 | 108 | 0.1445 | 603 | 0.362 | 172.26 | 45.00 | 1 | 0.4025 | 706 | 0.0023 | 27.82 | 6.291 | 0.2092 | 7207.4 | 660678 | 63600000 | 6400000000 | 0.4497 | 0.1988 | 0.0009 | 0.0000 | 0.0066 | 0.0000 | 0.0161 | 0.0031 | 0.0530 | 0.0093 | 0.1258 | 0.0322 | 0.1542 | 0.0811 | 0.1987 | 0.0619 | 0.2271 | 0.1002 | 0.2176 | 0.7123 | 0.0000 | 0.0000 | 0.0036 | 0.0000 | 0.0065 | 0.0017 | 0.0210 | 0.0035 | 0.0564 | 0.0239 | 0.0694 | 0.0554 | 0.0845 | 0.0309 | 0.1185 | 0.0612 | 0.6402 | 0.8233 | 0.0183 | 0.0101 | 0.0367 | 0.0202 | 0.0765 | 0.0808 | 0.1009 | 0.2121 | 0.1407 | 0.2323 | 0.1529 | 0.2222 | 0.1315 | 0.0909 | 0.1070 | 0.0909 | 0.2355 | 0.0404 | 0.0024 | 0.0120 | 0.0240 | 0.0456 | 0.0948 | 0.1116 | 0.1273 | 0.1645 | 0.4178 | 24 | 30 | 42 | 62 | 105 | 161 | 244 | 333 | 444 | 0.0173 | 43.47 | 5.837 | 0.3746 | 70533.6 | 37800000 | 24900000000 | 19100000000000 | 0.4742 | 0.1698 | 0.1259 | 0.0058 | 0.2370 | 0.0559 | 0.2840 | 0.2328 | 0.1457 | 0.1420 | 0.0889 | 0.1700 | 0.0617 | 0.1455 | 0.0420 | 0.0873 | 0.0099 | 0.0733 | 0.0049 | 0.0873 | 0.0011 | 0.0010 | 0.0028 | 0.0020 | 0.0091 | 0.0024 | 0.0300 | 0.0215 | 0.0935 | 0.0842 | 0.1230 | 0.1214 | 0.0941 | 0.0773 | 0.1423 | 0.1214 | 0.5040 | 0.5688 | 0.0007 | 0.0000 | 0.0059 | 0.0051 | 0.0074 | 0.0144 | 0.0368 | 0.0405 | 0.1177 | 0.1267 | 0.1575 | 0.1976 | 0.1302 | 0.1351 | 0.1707 | 0.1520 | 0.3731 | 0.3285 | 0.0013 | 0.0026 | 0.0059 | 0.0300 | 0.1019 | 0.1457 | 0.1130 | 0.1470 | 0.4526 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 644 | 509 | | 752 | 2601 | 109.3 | 22.70 | 27.66 | 36.83 | 79 | 89 | 97 | 104 | 110 | 117 | 123 | 130 | 139 | 0.1303 | 339 | 0.980 | 171.76 | 54.15 | 1 | 0.6197 | 466 | 0.0023 | 47.96 | 6.181 | 0.1607 | 12466.6 | 1470000 | 179000000 | 22400000000 | 0.3827 | 0.2423 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0151 | 0.0000 | 0.0538 | 0.0042 | 0.1075 | 0.0379 | 0.1613 | 0.0618 | 0.1527 | 0.0520 | 0.2022 | 0.0758 | 0.3032 | 0.7683 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0114 | 0.0041 | 0.0507 | 0.0346 | 0.0654 | 0.0553 | 0.0670 | 0.0346 | 0.1029 | 0.0581 | 0.7010 | 0.8133 | 0.0204 | 0.0000 | 0.0272 | 0.0909 | 0.0612 | 0.3636 | 0.0952 | 0.2727 | 0.1837 | 0.0909 | 0.1361 | 0.1818 | 0.1633 | 0.0000 | 0.1769 | 0.0000 | 0.1361 | 0.0000 | 0.0000 | 0.0025 | 0.0101 | 0.0404 | 0.0783 | 0.1364 | 0.1364 | 0.1338 | 0.4621 | 13 | 14 | 15 | 16 | 17 | 18 | 21 | 29 | 50 | 0.5312 | 1.01 | 1.471 | 0.9002 | 2121.0 | 439440 | 138000000 | 49900000000 | 0.6286 | 0.0988 | 0.0545 | 0.0328 | 0.0955 | 0.0864 | 0.2136 | 0.1351 | 0.2136 | 0.1033 | 0.1727 | 0.1360 | 0.1091 | 0.1360 | 0.0909 | 0.1241 | 0.0364 | 0.1311 | 0.0136 | 0.1152 | 0.0104 | 0.0219 | 0.0104 | 0.0629 | 0.0207 | 0.0950 | 0.0370 | 0.0673 | 0.1111 | 0.0994 | 0.1156 | 0.0892 | 0.1319 | 0.1001 | 0.1452 | 0.1235 | 0.4178 | 0.3406 | 0.0000 | 0.0000 | 0.0022 | 0.0249 | 0.0198 | 0.0305 | 0.0440 | 0.0693 | 0.1604 | 0.1662 | 0.1758 | 0.1801 | 0.1297 | 0.1468 | 0.1714 | 0.1634 | 0.2967 | 0.2188 | 0.0036 | 0.0073 | 0.0146 | 0.0419 | 0.1421 | 0.1512 | 0.1275 | 0.1658 | 0.3461 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 630 | 725 | | 3602 | 12705 | 123.5 | 28.89 | 207.97 | 184.41 | 91 | 99 | 107 | 113 | 120 | 127 | 135 | 145 | 162 | 0.0653 | 830 | 0.652 | 114.81 | 32.25 | 2 | 0.0999 | 360 | 0.0026 | 19.30 | 6.264 | 0.2653 | 16090.9 | 2210000 | 321000000 | 49000000000 | 0.4640 | 0.1807 | 0.0004 | 0.0000 | 0.0022 | 0.0000 | 0.0089 | 0.0003 | 0.0289 | 0.0036 | 0.1061 | 0.0245 | 0.1488 | 0.0660 | 0.1710 | 0.0554 | 0.1856 | 0.0845 | 0.3481 | 0.7657 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0000 | 0.0104 | 0.0020 | 0.0494 | 0.0165 | 0.0841 | 0.0414 | 0.0838 | 0.0255 | 0.1088 | 0.0448 | 0.6587 | 0.8698 | 0.0048 | 0.0136 | 0.0144 | 0.0317 | 0.0256 | 0.0226 | 0.0832 | 0.1448 | 0.1344 | 0.1584 | 0.1648 | 0.2579 | 0.1328 | 0.1041 | 0.1360 | 0.1176 | 0.3040 | 0.1493 | 0.0019 | 0.0080 | 0.0161 | 0.0427 | 0.0860 | 0.1373 | 0.1132 | 0.1429 | 0.4521 | 17 | 41 | 80 | 122 | 166 | 214 | 273 | 344 | 450 | 0.0066 | 49.93 | 6.596 | 0.3005 | 77256.1 | 39900000 | 27300000000 | 24000000000000 | 0.5228 | 0.1478 | 0.0366 | 0.0017 | 0.1741 | 0.0093 | 0.2322 | 0.0745 | 0.1644 | 0.1242 | 0.1732 | 0.1875 | 0.1185 | 0.1933 | 0.0585 | 0.1480 | 0.0307 | 0.1381 | 0.0117 | 0.1234 | 0.0005 | 0.0001 | 0.0017 | 0.0009 | 0.0038 | 0.0032 | 0.0202 | 0.0107 | 0.0760 | 0.0570 | 0.1225 | 0.1019 | 0.0993 | 0.0819 | 0.1496 | 0.1250 | 0.5266 | 0.6193 | 0.0012 | 0.0014 | 0.0023 | 0.0064 | 0.0098 | 0.0188 | 0.0393 | 0.0507 | 0.1129 | 0.1298 | 0.1665 | 0.1799 | 0.1234 | 0.1272 | 0.1737 | 0.1599 | 0.3709 | 0.3259 | 0.0010 | 0.0040 | 0.0082 | 0.0276 | 0.0888 | 0.1485 | 0.1189 | 0.1654 | 0.4377 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 502 | 891 | | 697 | 2813 | 320.4 | 207.81 | 13.17 | 5.09 | 98 | 125 | 170 | 212 | 264 | 326 | 402 | 514 | 669 | 0.1337 | 376 | 1.160 | 26.25 | 8.00 | 2 | 0.0918 | 64 | 0.0019 | 99.20 | 6.369 | 0.1311 | 145754.0 | 81100000 | 50300000000 | 33200000000000 | 0.2968 | 0.3295 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0303 | 0.0000 | 0.0909 | 0.0036 | 0.2348 | 0.1155 | 0.2348 | 0.1769 | 0.2273 | 0.1227 | 0.1288 | 0.1444 | 0.0530 | 0.4368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0084 | 0.0022 | 0.0503 | 0.0508 | 0.0670 | 0.0640 | 0.0475 | 0.0375 | 0.0587 | 0.0486 | 0.7682 | 0.7969 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0133 | 0.0114 | 0.0487 | 0.0739 | 0.1062 | 0.0966 | 0.0442 | 0.0568 | 0.0752 | 0.0852 | 0.7124 | 0.6761 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0565 | 0.0919 | 0.0389 | 0.0671 | 0.7420 | 7 | 9 | 10 | 12 | 13 | 14 | 15 | 17 | 20 | 0.4201 | 0.26 | 1.281 | 0.8672 | 199.4 | 3414.53 | 65866.6 | 1430000 | 0.5670 | 0.1264 | 0.0375 | 0.0039 | 0.0586 | 0.0218 | 0.0980 | 0.0262 | 0.1548 | 0.0510 | 0.1951 | 0.0694 | 0.2070 | 0.0879 | 0.1712 | 0.1422 | 0.0678 | 0.2146 | 0.0101 | 0.3830 | 0.0136 | 0.0020 | 0.0172 | 0.0131 | 0.0183 | 0.0127 | 0.0365 | 0.0295 | 0.0662 | 0.0516 | 0.0986 | 0.0540 | 0.1377 | 0.0704 | 0.2165 | 0.1101 | 0.3954 | 0.6566 | 0.0545 | 0.0966 | 0.0703 | 0.0914 | 0.0812 | 0.0914 | 0.1018 | 0.1227 | 0.1115 | 0.1488 | 0.1236 | 0.1488 | 0.1164 | 0.1175 | 0.1794 | 0.1071 | 0.1612 | 0.0757 | 0.0122 | 0.0278 | 0.0523 | 0.0733 | 0.1025 | 0.1263 | 0.1514 | 0.1826 | 0.2716 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 995 | 342 | | 564 | 6866 | 365.6 | 120.17 | 7.19 | 3.22 | 232 | 252 | 275 | 304 | 342 | 374 | 420 | 483 | 545 | 0.0756 | 519 | 0.945 | 118.23 | 29.12 | 4 | 0.5071 | 286 | 0.0058 | 7.76 | 5.422 | 0.3429 | 148105.0 | 65900000 | 31700000000 | 16200000000000 | 0.3696 | 0.2532 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0194 | 0.0133 | 0.1311 | 0.0421 | 0.2136 | 0.1242 | 0.1505 | 0.0643 | 0.1553 | 0.0931 | 0.3301 | 0.6630 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0083 | 0.0056 | 0.0500 | 0.0297 | 0.0667 | 0.0816 | 0.0444 | 0.0260 | 0.0639 | 0.0464 | 0.7667 | 0.8108 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0114 | 0.0195 | 0.0341 | 0.0779 | 0.0909 | 0.0974 | 0.1250 | 0.0649 | 0.0568 | 0.0779 | 0.1591 | 0.6623 | 0.5227 | 0.0000 | 0.0000 | 0.0000 | 0.0082 | 0.0617 | 0.0864 | 0.0453 | 0.0864 | 0.7119 | 4 | 4 | 5 | 6 | 7 | 7 | 8 | 10 | 12 | 0.0970 | 0.30 | 0.907 | 0.3778 | 62.0 | 621.741 | 7050.74 | 88336.7 | 0.5310 | 0.1386 | 0.0333 | 0.0083 | 0.0940 | 0.0274 | 0.1573 | 0.0625 | 0.2031 | 0.1170 | 0.2115 | 0.1983 | 0.1705 | 0.2399 | 0.0918 | 0.2042 | 0.0329 | 0.1141 | 0.0055 | 0.0284 | 0.0071 | 0.0004 | 0.0280 | 0.0051 | 0.0552 | 0.0227 | 0.0722 | 0.0545 | 0.0905 | 0.0935 | 0.1106 | 0.1358 | 0.1192 | 0.1525 | 0.1513 | 0.1718 | 0.3659 | 0.3639 | 0.0766 | 0.0859 | 0.0697 | 0.0791 | 0.0676 | 0.0846 | 0.0855 | 0.0784 | 0.0907 | 0.0914 | 0.1096 | 0.1153 | 0.1311 | 0.1535 | 0.1809 | 0.1869 | 0.1883 | 0.1248 | 0.0208 | 0.0594 | 0.0898 | 0.1063 | 0.1084 | 0.1039 | 0.0962 | 0.1215 | 0.2938 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 701 | 317 | | 1010 | 1709 | 117.2 | 14.08 | 14.40 | 13.12 | 99 | 104 | 109 | 112 | 117 | 120 | 125 | 130 | 137 | 0.2264 | 387 | 0.804 | 89.94 | 22.63 | 3 | 0.2515 | 254 | 0.0285 | 1.46 | 3.784 | 0.5971 | 13944.3 | 1680000 | 206000000 | 25500000000 | 0.4094 | 0.2171 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0032 | 0.0010 | 0.0173 | 0.0079 | 0.0539 | 0.0366 | 0.0949 | 0.0772 | 0.0949 | 0.0475 | 0.1284 | 0.0554 | 0.6063 | 0.7743 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0031 | 0.0010 | 0.0153 | 0.0079 | 0.0408 | 0.0366 | 0.0704 | 0.0772 | 0.0551 | 0.0475 | 0.0643 | 0.0554 | 0.7500 | 0.7743 | 0.0755 | 0.0000 | 0.0566 | 0.0000 | 0.0755 | 0.0000 | 0.3019 | 0.0000 | 0.1509 | 0.0000 | 0.1698 | 0.0000 | 0.0566 | 0.0000 | 0.0755 | 0.0000 | 0.0377 | 0.0000 | 0.0000 | 0.0119 | 0.0119 | 0.0356 | 0.0652 | 0.1047 | 0.1126 | 0.1285 | 0.5296 | 6 | 7 | 8 | 9 | 10 | 12 | 14 | 18 | 27 | 0.2146 | 0.58 | 2.293 | 0.8004 | 379.5 | 17210.3 | 1060000 | 75400000 | 0.6023 | 0.1002 | 0.1389 | 0.0185 | 0.1528 | 0.0420 | 0.1910 | 0.0791 | 0.2014 | 0.1471 | 0.1632 | 0.1483 | 0.0868 | 0.1508 | 0.0417 | 0.1434 | 0.0243 | 0.1434 | 0.0000 | 0.1273 | 0.0532 | 0.0116 | 0.0388 | 0.0268 | 0.0403 | 0.0528 | 0.0446 | 0.0966 | 0.0935 | 0.1109 | 0.1410 | 0.1270 | 0.0777 | 0.1064 | 0.1410 | 0.1145 | 0.3698 | 0.3533 | 0.0197 | 0.0032 | 0.0221 | 0.0194 | 0.0246 | 0.0227 | 0.0491 | 0.0680 | 0.1302 | 0.1262 | 0.1474 | 0.1780 | 0.1179 | 0.1197 | 0.1843 | 0.1586 | 0.3047 | 0.3042 | 0.0209 | 0.0209 | 0.0342 | 0.0512 | 0.0892 | 0.1518 | 0.0854 | 0.1613 | 0.3852 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 146 | 51 | | 354 | 2232 | 83.5 | 10.81 | 232.77 | 142.92 | 70 | 73 | 77 | 80 | 83 | 86 | 89 | 94 | 99 | 0.1223 | 273 | 1.033 | 88.84 | 22.85 | 0 | 0.5791 | 205 | 0.0101 | 9.66 | 4.753 | 0.3349 | 7088.7 | 611712 | 53600000 | 4780000000 | 0.4194 | 0.1966 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0130 | 0.0028 | 0.0357 | 0.0085 | 0.0779 | 0.0397 | 0.1331 | 0.1473 | 0.1331 | 0.0368 | 0.2110 | 0.0822 | 0.3929 | 0.6827 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0030 | 0.0028 | 0.0178 | 0.0056 | 0.0562 | 0.0424 | 0.1124 | 0.1441 | 0.0621 | 0.0339 | 0.1213 | 0.0763 | 0.6243 | 0.6949 | 0.0000 | 1.0000 | 0.1000 | 0.0000 | 0.3667 | 0.0000 | 0.1000 | 0.0000 | 0.1667 | 0.0000 | 0.1333 | 0.0000 | 0.0667 | 0.0000 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0430 | 0.0699 | 0.1505 | 0.1720 | 0.1290 | 0.1559 | 0.2688 | 68 | 106 | 142 | 176 | 210 | 248 | 292 | 342 | 423 | 0.0013 | 85.74 | 6.901 | 0.1836 | 74597.8 | 29500000 | 13700000000 | 7190000000000 | 0.4379 | 0.1909 | 0.0169 | 0.0028 | 0.0639 | 0.0075 | 0.1899 | 0.0197 | 0.2199 | 0.0563 | 0.1748 | 0.1315 | 0.1485 | 0.1840 | 0.0846 | 0.1897 | 0.0639 | 0.1615 | 0.0376 | 0.2469 | 0.0008 | 0.0013 | 0.0016 | 0.0019 | 0.0055 | 0.0044 | 0.0181 | 0.0120 | 0.0604 | 0.0405 | 0.1319 | 0.0790 | 0.0981 | 0.0765 | 0.1389 | 0.0967 | 0.5447 | 0.6877 | 0.0013 | 0.0039 | 0.0054 | 0.0135 | 0.0148 | 0.0271 | 0.0620 | 0.0832 | 0.1334 | 0.1605 | 0.1536 | 0.1741 | 0.1361 | 0.1586 | 0.1860 | 0.1470 | 0.3073 | 0.2321 | 0.0000 | 0.0020 | 0.0121 | 0.0302 | 0.1099 | 0.1532 | 0.1149 | 0.1734 | 0.4042 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 735 | 406 | | 428 | 1601 | 77.0 | 10.85 | 11.27 | 14.00 | 65 | 67 | 70 | 72 | 75 | 77 | 82 | 86 | 93 | 0.1643 | 263 | 0.708 | 113.88 | 25.02 | 1 | 0.6636 | 284 | 0.0441 | 1.02 | 3.411 | 0.6516 | 6040.7 | 483894 | 39600000 | 3310000000 | 0.3996 | 0.2382 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0053 | 0.0024 | 0.0718 | 0.0447 | 0.1011 | 0.0753 | 0.0638 | 0.0400 | 0.1277 | 0.0918 | 0.6303 | 0.7435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0047 | 0.0023 | 0.0498 | 0.0444 | 0.0687 | 0.0724 | 0.0332 | 0.0304 | 0.0782 | 0.0748 | 0.7654 | 0.7734 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 1.0000 | 0.0217 | 0.0000 | 0.1739 | 0.0000 | 0.1304 | 0.0000 | 0.1304 | 0.0000 | 0.1522 | 0.0000 | 0.3478 | 0.0000 | 0.0053 | 0.0000 | 0.0105 | 0.0474 | 0.0579 | 0.1000 | 0.0947 | 0.1263 | 0.5579 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 12 | 15 | 0.6009 | 2.10 | 1.178 | 0.8849 | 322.9 | 27681.3 | 3820000 | 619000000 | 0.6572 | 0.0788 | 0.0682 | 0.0020 | 0.1326 | 0.0188 | 0.1111 | 0.0683 | 0.1189 | 0.0960 | 0.1598 | 0.1317 | 0.1774 | 0.1545 | 0.1365 | 0.1535 | 0.0741 | 0.1723 | 0.0214 | 0.2030 | 0.0477 | 0.0017 | 0.0846 | 0.0145 | 0.0682 | 0.0513 | 0.0628 | 0.0803 | 0.1010 | 0.1103 | 0.1173 | 0.1350 | 0.1119 | 0.1325 | 0.1364 | 0.1556 | 0.2701 | 0.3188 | 0.0591 | 0.0313 | 0.0727 | 0.0313 | 0.0364 | 0.0313 | 0.0591 | 0.0625 | 0.0773 | 0.1188 | 0.1545 | 0.1688 | 0.1364 | 0.1813 | 0.1909 | 0.2125 | 0.2136 | 0.1625 | 0.0592 | 0.0547 | 0.0661 | 0.0957 | 0.1207 | 0.1276 | 0.1116 | 0.1344 | 0.2301 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 79 | 365 | | 355 | 368 | 98.5 | 34.30 | 743.33 | 441.89 | 53 | 66 | 81 | 90 | 95 | 105 | 117 | 132 | 143 | 0.3995 | 147 | 1.183 | 36.12 | 15.52 | 1 | 0.2817 | 100 | 0.0040 | 43.26 | 5.614 | 0.2000 | 10879.1 | 1310000 | 169000000 | 22900000000 | 0.3710 | 0.2410 | 0.0000 | 0.0000 | 0.0265 | 0.0000 | 0.1060 | 0.0041 | 0.0927 | 0.0122 | 0.1258 | 0.1306 | 0.2053 | 0.1796 | 0.1589 | 0.1469 | 0.1126 | 0.1429 | 0.1722 | 0.3837 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0159 | 0.0067 | 0.0556 | 0.0669 | 0.1032 | 0.0635 | 0.0635 | 0.0535 | 0.1111 | 0.0702 | 0.6468 | 0.7391 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0297 | 0.1111 | 0.0792 | 0.2037 | 0.1386 | 0.2037 | 0.2673 | 0.2037 | 0.1287 | 0.1296 | 0.1287 | 0.1111 | 0.2277 | 0.0370 | 0.0000 | 0.0060 | 0.0060 | 0.0539 | 0.1257 | 0.1796 | 0.0958 | 0.1796 | 0.3533 | 167 | 338 | 432 | 575 | 717 | 837 | 975 | 1120 | 1332 | 0.0029 | 177.01 | 5.867 | 0.1008 | 747281.0 | 884000000 | 1170000000000 | 1.66E+15 | 0.3788 | 0.2356 | 0.0116 | 0.0127 | 0.1744 | 0.0570 | 0.2209 | 0.0633 | 0.2326 | 0.1266 | 0.1512 | 0.2089 | 0.1279 | 0.1835 | 0.0814 | 0.1835 | 0.0000 | 0.0886 | 0.0000 | 0.0759 | 0.0000 | 0.0040 | 0.0230 | 0.0199 | 0.0230 | 0.0199 | 0.0829 | 0.0598 | 0.1429 | 0.1474 | 0.1060 | 0.1235 | 0.1567 | 0.1474 | 0.1751 | 0.1633 | 0.2903 | 0.3147 | 0.0000 | 0.0000 | 0.0076 | 0.0108 | 0.0458 | 0.0323 | 0.0458 | 0.0860 | 0.2061 | 0.2688 | 0.1756 | 0.2151 | 0.1374 | 0.1720 | 0.2443 | 0.1828 | 0.1374 | 0.0323 | 0.0058 | 0.0173 | 0.0405 | 0.0578 | 0.1214 | 0.1445 | 0.1792 | 0.1850 | 0.2486 |