High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 895 | 609 | | 4883 | 16388 | 528.4 | 82.82 | 129.28 | 239.46 | 424 | 462 | 486 | 505 | 525 | 545 | 568 | 595 | 639 | 0.0616 | 1009 | 0.725 | 104.48 | 25.55 | 1 | 0.0555 | 271 | 0.0023 | 18.30 | 6.393 | 0.2729 | 286071.0 | 158000000 | 89700000000 | 51900000000000 | 0.4173 | 0.2298 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0054 | 0.0004 | 0.0293 | 0.0147 | 0.0673 | 0.0263 | 0.0671 | 0.0165 | 0.1041 | 0.0296 | 0.7248 | 0.9125 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0004 | 0.0181 | 0.0138 | 0.0331 | 0.0232 | 0.0342 | 0.0135 | 0.0512 | 0.0220 | 0.8611 | 0.9271 | 0.0036 | 0.0000 | 0.0018 | 0.0000 | 0.0309 | 0.0882 | 0.0436 | 0.2353 | 0.1291 | 0.2941 | 0.1673 | 0.0882 | 0.0800 | 0.1765 | 0.1436 | 0.0882 | 0.4000 | 0.0294 | 0.0013 | 0.0051 | 0.0131 | 0.0300 | 0.0656 | 0.1016 | 0.0863 | 0.1121 | 0.5849 | 7 | 9 | 10 | 11 | 13 | 18 | 55 | 222 | 459 | 0.2514 | 33.66 | 3.796 | 0.6421 | 74049.5 | 59100000 | 55800000000 | 58800000000000 | 0.5654 | 0.1070 | 0.1457 | 0.0103 | 0.2870 | 0.0432 | 0.3576 | 0.2613 | 0.1369 | 0.2469 | 0.0397 | 0.2171 | 0.0221 | 0.1235 | 0.0110 | 0.0463 | 0.0000 | 0.0267 | 0.0000 | 0.0247 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0009 | 0.0004 | 0.0085 | 0.0063 | 0.0461 | 0.0469 | 0.0811 | 0.0735 | 0.0507 | 0.0480 | 0.0726 | 0.0676 | 0.7401 | 0.7571 | 0.0000 | 0.0003 | 0.0005 | 0.0000 | 0.0013 | 0.0030 | 0.0108 | 0.0120 | 0.0569 | 0.0569 | 0.0857 | 0.0867 | 0.0607 | 0.0684 | 0.0810 | 0.0878 | 0.7031 | 0.6848 | 0.0000 | 0.0000 | 0.0005 | 0.0097 | 0.0508 | 0.0832 | 0.0557 | 0.0735 | 0.7266 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 564 | 834 | | 5735 | 9264 | 386.5 | 90.39 | 113.25 | 134.91 | 287 | 312 | 332 | 351 | 371 | 393 | 423 | 457 | 512 | 0.0955 | 885 | 1.153 | 94.87 | 36.50 | 1 | 0.0424 | 243 | 0.0010 | 39.47 | 7.169 | 0.1888 | 157556.0 | 67800000 | 30700000000 | 14700000000000 | 0.4429 | 0.2115 | 0.0008 | 0.0000 | 0.0019 | 0.0006 | 0.0036 | 0.0017 | 0.0202 | 0.0044 | 0.0679 | 0.0189 | 0.1422 | 0.0466 | 0.1486 | 0.0405 | 0.1705 | 0.0615 | 0.4443 | 0.8259 | 0.0004 | 0.0000 | 0.0011 | 0.0002 | 0.0024 | 0.0009 | 0.0105 | 0.0021 | 0.0358 | 0.0126 | 0.0710 | 0.0308 | 0.0693 | 0.0219 | 0.0813 | 0.0324 | 0.7282 | 0.8991 | 0.0076 | 0.0105 | 0.0123 | 0.0026 | 0.0123 | 0.0211 | 0.0550 | 0.0632 | 0.0920 | 0.1395 | 0.1404 | 0.1447 | 0.0920 | 0.1289 | 0.1262 | 0.1421 | 0.4620 | 0.3474 | 0.0012 | 0.0032 | 0.0097 | 0.0385 | 0.0838 | 0.1187 | 0.0956 | 0.1126 | 0.5367 | 9 | 11 | 13 | 22 | 52 | 96 | 147 | 211 | 309 | 0.0380 | 20.61 | 5.347 | 0.4709 | 31025.6 | 11600000 | 5240000000 | 2690000000000 | 0.6389 | 0.0617 | 0.0305 | 0.0023 | 0.1469 | 0.0170 | 0.2362 | 0.0978 | 0.1627 | 0.1213 | 0.1345 | 0.1582 | 0.0949 | 0.1687 | 0.0983 | 0.1201 | 0.0588 | 0.1125 | 0.0373 | 0.2021 | 0.0005 | 0.0000 | 0.0003 | 0.0002 | 0.0016 | 0.0026 | 0.0128 | 0.0086 | 0.0534 | 0.0432 | 0.0826 | 0.0776 | 0.0631 | 0.0491 | 0.1081 | 0.0918 | 0.6777 | 0.7269 | 0.0000 | 0.0008 | 0.0010 | 0.0008 | 0.0054 | 0.0051 | 0.0217 | 0.0249 | 0.0633 | 0.0785 | 0.1178 | 0.1224 | 0.0796 | 0.0890 | 0.1260 | 0.1383 | 0.5852 | 0.5404 | 0.0000 | 0.0006 | 0.0027 | 0.0183 | 0.0601 | 0.0914 | 0.0787 | 0.1213 | 0.6269 | ||
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1088 | 669 | | 5843 | 18102 | 400.3 | 70.70 | 111.60 | 175.03 | 313 | 337 | 359 | 378 | 396 | 414 | 435 | 460 | 494 | 0.0658 | 1192 | 1.022 | 100.70 | 29.21 | 2 | 0.0419 | 245 | 0.0028 | 13.59 | 6.176 | 0.2930 | 165240.0 | 70300000 | 30800000000 | 13800000000000 | 0.4364 | 0.2115 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0009 | 0.0000 | 0.0101 | 0.0002 | 0.0406 | 0.0147 | 0.0975 | 0.0268 | 0.1026 | 0.0251 | 0.1475 | 0.0400 | 0.5998 | 0.8933 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0004 | 0.0000 | 0.0055 | 0.0002 | 0.0189 | 0.0124 | 0.0447 | 0.0197 | 0.0447 | 0.0124 | 0.0609 | 0.0210 | 0.8245 | 0.9344 | 0.0127 | 0.0259 | 0.0152 | 0.0690 | 0.0279 | 0.0517 | 0.0735 | 0.1552 | 0.1343 | 0.2241 | 0.1901 | 0.1897 | 0.1166 | 0.0948 | 0.1445 | 0.1034 | 0.2852 | 0.0862 | 0.0014 | 0.0032 | 0.0064 | 0.0278 | 0.0642 | 0.1063 | 0.1131 | 0.1302 | 0.5474 | 6 | 8 | 9 | 11 | 17 | 44 | 108 | 202 | 366 | 0.1406 | 16.27 | 4.291 | 0.5900 | 43085.6 | 23700000 | 15800000000 | 12200000000000 | 0.5499 | 0.1047 | 0.0414 | 0.0055 | 0.1545 | 0.0135 | 0.3162 | 0.0897 | 0.1505 | 0.1440 | 0.1222 | 0.2063 | 0.0949 | 0.2123 | 0.0535 | 0.1191 | 0.0384 | 0.0927 | 0.0283 | 0.1171 | 0.0000 | 0.0003 | 0.0002 | 0.0005 | 0.0009 | 0.0011 | 0.0063 | 0.0089 | 0.0455 | 0.0402 | 0.0747 | 0.0668 | 0.0468 | 0.0519 | 0.0788 | 0.0678 | 0.7469 | 0.7626 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0019 | 0.0027 | 0.0123 | 0.0113 | 0.0483 | 0.0583 | 0.0924 | 0.0945 | 0.0621 | 0.0730 | 0.0868 | 0.0995 | 0.6955 | 0.6602 | 0.0000 | 0.0002 | 0.0009 | 0.0078 | 0.0487 | 0.0782 | 0.0567 | 0.0840 | 0.7235 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 312 | 733 | | 7233 | 20217 | 523.9 | 88.32 | 192.73 | 354.08 | 412 | 444 | 470 | 496 | 519 | 544 | 571 | 604 | 641 | 0.0504 | 1018 | 1.154 | 114.98 | 42.58 | 1 | 0.0408 | 295 | 0.0018 | 19.88 | 6.575 | 0.2459 | 282245.0 | 156000000 | 88600000000 | 51500000000000 | 0.4172 | 0.2311 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0003 | 0.0114 | 0.0004 | 0.0461 | 0.0113 | 0.0920 | 0.0228 | 0.1143 | 0.0150 | 0.1514 | 0.0291 | 0.5824 | 0.9210 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0046 | 0.0001 | 0.0219 | 0.0096 | 0.0442 | 0.0195 | 0.0517 | 0.0096 | 0.0720 | 0.0186 | 0.8052 | 0.9427 | 0.0032 | 0.0494 | 0.0085 | 0.0247 | 0.0481 | 0.0617 | 0.1068 | 0.2099 | 0.1474 | 0.1481 | 0.1699 | 0.1728 | 0.1453 | 0.1605 | 0.1271 | 0.1111 | 0.2436 | 0.0617 | 0.0014 | 0.0026 | 0.0072 | 0.0203 | 0.0629 | 0.1090 | 0.0973 | 0.1296 | 0.5697 | 10 | 12 | 14 | 16 | 19 | 32 | 110 | 339 | 644 | 0.1456 | 63.21 | 4.433 | 0.6015 | 162507.0 | 200000000 | 303000000000 | 525000000000000 | 0.5064 | 0.1533 | 0.1318 | 0.0049 | 0.3100 | 0.0323 | 0.3324 | 0.2391 | 0.1234 | 0.2742 | 0.0561 | 0.2167 | 0.0351 | 0.1220 | 0.0042 | 0.0617 | 0.0056 | 0.0358 | 0.0014 | 0.0133 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0005 | 0.0003 | 0.0070 | 0.0065 | 0.0491 | 0.0410 | 0.0772 | 0.0740 | 0.0498 | 0.0478 | 0.0813 | 0.0702 | 0.7351 | 0.7600 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0004 | 0.0017 | 0.0119 | 0.0114 | 0.0544 | 0.0623 | 0.0908 | 0.0925 | 0.0634 | 0.0717 | 0.0934 | 0.1071 | 0.6854 | 0.6531 | 0.0000 | 0.0002 | 0.0008 | 0.0084 | 0.0511 | 0.0851 | 0.0532 | 0.0876 | 0.7136 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 686 | 761 | | 4278 | 10329 | 575.0 | 101.74 | 209.00 | 348.06 | 451 | 485 | 515 | 540 | 564 | 591 | 619 | 660 | 717 | 0.0947 | 978 | 1.233 | 88.57 | 39.70 | 1 | 0.0570 | 244 | 0.0015 | 26.90 | 6.732 | 0.2213 | 340946.0 | 208000000 | 131000000000 | 85100000000000 | 0.4370 | 0.2089 | 0.0003 | 0.0002 | 0.0016 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0005 | 0.0491 | 0.0165 | 0.1035 | 0.0326 | 0.1032 | 0.0271 | 0.1478 | 0.0398 | 0.5865 | 0.8833 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0005 | 0.0000 | 0.0035 | 0.0002 | 0.0289 | 0.0138 | 0.0516 | 0.0248 | 0.0503 | 0.0145 | 0.0751 | 0.0227 | 0.7893 | 0.9239 | 0.0017 | 0.0000 | 0.0017 | 0.0408 | 0.0166 | 0.0510 | 0.0582 | 0.1633 | 0.1481 | 0.2041 | 0.1681 | 0.2245 | 0.0899 | 0.0714 | 0.1514 | 0.1633 | 0.3644 | 0.0816 | 0.0010 | 0.0000 | 0.0051 | 0.0314 | 0.0663 | 0.1352 | 0.1023 | 0.1180 | 0.5408 | 9 | 10 | 12 | 14 | 19 | 49 | 188 | 394 | 707 | 0.1793 | 74.24 | 4.505 | 0.5801 | 164813.0 | 178000000 | 227000000000 | 323000000000000 | 0.5252 | 0.1228 | 0.1229 | 0.0022 | 0.3301 | 0.0673 | 0.2337 | 0.2076 | 0.1108 | 0.1987 | 0.0723 | 0.2065 | 0.0723 | 0.1358 | 0.0313 | 0.0550 | 0.0193 | 0.0673 | 0.0072 | 0.0595 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0013 | 0.0020 | 0.0041 | 0.0055 | 0.0525 | 0.0486 | 0.0965 | 0.0858 | 0.0600 | 0.0532 | 0.0839 | 0.0776 | 0.7008 | 0.7272 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0014 | 0.0012 | 0.0090 | 0.0196 | 0.0690 | 0.0667 | 0.1063 | 0.1181 | 0.0788 | 0.0895 | 0.1095 | 0.1071 | 0.6259 | 0.5958 | 0.0000 | 0.0003 | 0.0000 | 0.0104 | 0.0509 | 0.1031 | 0.0686 | 0.0961 | 0.6707 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1223 | 452 | | 6155 | 9803 | 128.7 | 28.06 | 148.51 | 137.13 | 95 | 105 | 112 | 119 | 126 | 133 | 141 | 152 | 166 | 0.0870 | 853 | 0.535 | 195.17 | 41.62 | 2 | 0.0980 | 603 | 0.0012 | 37.11 | 6.972 | 0.1989 | 17339.8 | 2450000 | 361000000 | 55800000000 | 0.4378 | 0.2119 | 0.0003 | 0.0000 | 0.0015 | 0.0000 | 0.0054 | 0.0000 | 0.0219 | 0.0026 | 0.0706 | 0.0184 | 0.1443 | 0.0426 | 0.1512 | 0.0447 | 0.1856 | 0.0693 | 0.4192 | 0.8224 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0022 | 0.0000 | 0.0078 | 0.0007 | 0.0301 | 0.0139 | 0.0603 | 0.0269 | 0.0630 | 0.0203 | 0.0920 | 0.0328 | 0.7436 | 0.9054 | 0.0055 | 0.0231 | 0.0156 | 0.0423 | 0.0294 | 0.1000 | 0.0725 | 0.1577 | 0.1330 | 0.1577 | 0.1982 | 0.1731 | 0.1330 | 0.1269 | 0.1450 | 0.0885 | 0.2679 | 0.1308 | 0.0021 | 0.0067 | 0.0102 | 0.0376 | 0.0709 | 0.1254 | 0.1180 | 0.1394 | 0.4898 | 14 | 24 | 55 | 81 | 109 | 144 | 187 | 247 | 346 | 0.0183 | 16.97 | 5.620 | 0.4458 | 40857.3 | 15200000 | 6830000000 | 3500000000000 | 0.6750 | 0.0565 | 0.0233 | 0.0013 | 0.1047 | 0.0122 | 0.2115 | 0.0411 | 0.1937 | 0.0746 | 0.1814 | 0.1677 | 0.1513 | 0.1982 | 0.0767 | 0.1700 | 0.0431 | 0.1519 | 0.0144 | 0.1831 | 0.0004 | 0.0005 | 0.0002 | 0.0013 | 0.0026 | 0.0023 | 0.0199 | 0.0116 | 0.0656 | 0.0497 | 0.1179 | 0.0886 | 0.0905 | 0.0744 | 0.1297 | 0.1150 | 0.5731 | 0.6565 | 0.0000 | 0.0012 | 0.0016 | 0.0051 | 0.0090 | 0.0086 | 0.0347 | 0.0451 | 0.1006 | 0.1221 | 0.1546 | 0.1495 | 0.1060 | 0.1197 | 0.1375 | 0.1436 | 0.4560 | 0.4050 | 0.0003 | 0.0016 | 0.0047 | 0.0229 | 0.0938 | 0.1286 | 0.0967 | 0.1442 | 0.5071 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1215 | 861 | | 3007 | 9908 | 716.7 | 136.15 | 119.32 | 267.01 | 537 | 590 | 633 | 674 | 713 | 750 | 795 | 845 | 901 | 0.0779 | 772 | 1.131 | 79.76 | 31.58 | 2 | 0.0725 | 218 | 0.0010 | 52.74 | 7.117 | 0.1610 | 532255.0 | 408000000 | 323000000000 | 262000000000000 | 0.4330 | 0.2090 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0007 | 0.0651 | 0.0200 | 0.1481 | 0.0312 | 0.1456 | 0.0346 | 0.1792 | 0.0481 | 0.4484 | 0.8654 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0007 | 0.0316 | 0.0198 | 0.0643 | 0.0271 | 0.0583 | 0.0218 | 0.0671 | 0.0305 | 0.7723 | 0.9001 | 0.0040 | 0.0588 | 0.0059 | 0.0588 | 0.0198 | 0.0882 | 0.0931 | 0.3529 | 0.1802 | 0.2941 | 0.1842 | 0.0588 | 0.0911 | 0.0294 | 0.1564 | 0.0588 | 0.2653 | 0.0000 | 0.0000 | 0.0007 | 0.0041 | 0.0244 | 0.0807 | 0.1404 | 0.1065 | 0.1303 | 0.5129 | 7 | 9 | 10 | 11 | 13 | 16 | 31 | 132 | 393 | 0.2663 | 40.82 | 3.458 | 0.6732 | 85524.5 | 93100000 | 121000000000 | 174000000000000 | 0.6043 | 0.0864 | 0.1806 | 0.0164 | 0.2843 | 0.1228 | 0.2274 | 0.2439 | 0.1237 | 0.1735 | 0.1304 | 0.1571 | 0.0201 | 0.1489 | 0.0201 | 0.0687 | 0.0134 | 0.0491 | 0.0000 | 0.0196 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0063 | 0.0059 | 0.0680 | 0.0675 | 0.1151 | 0.0990 | 0.0657 | 0.0671 | 0.1024 | 0.0998 | 0.6425 | 0.6607 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0115 | 0.0085 | 0.0781 | 0.0846 | 0.1289 | 0.1455 | 0.0849 | 0.0795 | 0.1226 | 0.1286 | 0.5734 | 0.5516 | 0.0000 | 0.0000 | 0.0010 | 0.0097 | 0.0711 | 0.1178 | 0.0808 | 0.1168 | 0.6027 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 739 | 828 | | 3336 | 10996 | 733.4 | 131.67 | 162.29 | 302.51 | 560 | 619 | 661 | 696 | 729 | 766 | 805 | 848 | 907 | 0.0851 | 936 | 1.020 | 70.01 | 22.36 | 1 | 0.0525 | 175 | 0.0011 | 45.93 | 7.024 | 0.1864 | 555153.0 | 433000000 | 346000000000 | 284000000000000 | 0.4491 | 0.1924 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0070 | 0.0003 | 0.0488 | 0.0168 | 0.1141 | 0.0324 | 0.0930 | 0.0251 | 0.1439 | 0.0321 | 0.5920 | 0.8934 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0003 | 0.0255 | 0.0157 | 0.0541 | 0.0275 | 0.0375 | 0.0151 | 0.0620 | 0.0236 | 0.8185 | 0.9178 | 0.0041 | 0.0000 | 0.0000 | 0.0541 | 0.0269 | 0.1081 | 0.0579 | 0.2432 | 0.1467 | 0.1892 | 0.2004 | 0.2973 | 0.1240 | 0.0270 | 0.1508 | 0.0541 | 0.2893 | 0.0270 | 0.0000 | 0.0025 | 0.0105 | 0.0215 | 0.0732 | 0.0942 | 0.0905 | 0.1046 | 0.6031 | 8 | 10 | 11 | 12 | 14 | 20 | 71 | 262 | 593 | 0.2612 | 53.14 | 3.819 | 0.6522 | 117840.0 | 116000000 | 132000000000 | 164000000000000 | 0.5865 | 0.0859 | 0.1144 | 0.0083 | 0.2779 | 0.0904 | 0.2861 | 0.2629 | 0.1417 | 0.1599 | 0.1063 | 0.1460 | 0.0436 | 0.1252 | 0.0272 | 0.0918 | 0.0027 | 0.0668 | 0.0000 | 0.0487 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0007 | 0.0007 | 0.0093 | 0.0101 | 0.0593 | 0.0520 | 0.1052 | 0.1002 | 0.0576 | 0.0598 | 0.1014 | 0.0881 | 0.6657 | 0.6888 | 0.0000 | 0.0008 | 0.0008 | 0.0013 | 0.0024 | 0.0051 | 0.0154 | 0.0166 | 0.0675 | 0.0696 | 0.1110 | 0.1099 | 0.0667 | 0.0743 | 0.1082 | 0.1002 | 0.6280 | 0.6222 | 0.0000 | 0.0007 | 0.0011 | 0.0136 | 0.0618 | 0.1045 | 0.0674 | 0.0986 | 0.6522 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1060 | 312 | | 8531 | 15239 | 406.2 | 51.13 | 226.15 | 245.25 | 342 | 364 | 380 | 392 | 404 | 416 | 431 | 449 | 474 | 0.0668 | 1018 | 0.868 | 57.87 | 17.89 | 1 | 0.0178 | 152 | 0.0013 | 38.37 | 6.954 | 0.1978 | 167626.0 | 70200000 | 29900000000 | 12900000000000 | 0.4561 | 0.1965 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0013 | 0.0000 | 0.0042 | 0.0000 | 0.0191 | 0.0097 | 0.0469 | 0.0162 | 0.0566 | 0.0088 | 0.0892 | 0.0171 | 0.7825 | 0.9482 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0011 | 0.0000 | 0.0126 | 0.0097 | 0.0255 | 0.0162 | 0.0268 | 0.0088 | 0.0439 | 0.0152 | 0.8900 | 0.9501 | 0.0146 | 1.0000 | 0.0419 | 0.0000 | 0.0419 | 0.0000 | 0.1129 | 0.0000 | 0.1548 | 0.0000 | 0.1876 | 0.0000 | 0.1220 | 0.0000 | 0.1275 | 0.0000 | 0.1967 | 0.0000 | 0.0026 | 0.0043 | 0.0115 | 0.0412 | 0.0740 | 0.1178 | 0.1135 | 0.1283 | 0.5068 | 15 | 19 | 31 | 68 | 137 | 220 | 311 | 421 | 569 | 0.0214 | 62.72 | 6.209 | 0.3748 | 111286.0 | 74000000 | 60400000000 | 58100000000000 | 0.5099 | 0.1391 | 0.0526 | 0.0022 | 0.1940 | 0.0114 | 0.2544 | 0.1134 | 0.1674 | 0.1438 | 0.1298 | 0.1878 | 0.1032 | 0.1837 | 0.0545 | 0.1188 | 0.0292 | 0.1096 | 0.0149 | 0.1292 | 0.0000 | 0.0001 | 0.0001 | 0.0004 | 0.0007 | 0.0003 | 0.0079 | 0.0047 | 0.0500 | 0.0399 | 0.0844 | 0.0694 | 0.0697 | 0.0522 | 0.1028 | 0.0844 | 0.6841 | 0.7486 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0027 | 0.0049 | 0.0148 | 0.0281 | 0.0769 | 0.0926 | 0.1317 | 0.1530 | 0.1039 | 0.1070 | 0.1377 | 0.1459 | 0.5322 | 0.4672 | 0.0000 | 0.0000 | 0.0020 | 0.0090 | 0.0602 | 0.1073 | 0.0860 | 0.1254 | 0.6102 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1056 | 445 | | 5104 | 5780 | 74.9 | 19.31 | 218.45 | 175.33 | 50 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 100 | 0.1151 | 665 | 0.283 | 207.13 | 44.00 | 2 | 0.1532 | 782 | 0.0025 | 15.54 | 6.261 | 0.2795 | 5985.4 | 506947 | 45300000 | 4250000000 | 0.4661 | 0.1911 | 0.0004 | 0.0002 | 0.0039 | 0.0011 | 0.0191 | 0.0004 | 0.0399 | 0.0051 | 0.1042 | 0.0308 | 0.1402 | 0.0523 | 0.1568 | 0.0660 | 0.1812 | 0.0959 | 0.3543 | 0.7482 | 0.0000 | 0.0002 | 0.0010 | 0.0006 | 0.0066 | 0.0004 | 0.0081 | 0.0019 | 0.0403 | 0.0196 | 0.0608 | 0.0315 | 0.0613 | 0.0313 | 0.0861 | 0.0500 | 0.7359 | 0.8646 | 0.0063 | 0.0116 | 0.0188 | 0.0203 | 0.0385 | 0.0698 | 0.0626 | 0.1221 | 0.1181 | 0.1977 | 0.1503 | 0.1599 | 0.1351 | 0.1279 | 0.1485 | 0.1541 | 0.3220 | 0.1366 | 0.0024 | 0.0020 | 0.0083 | 0.0317 | 0.0797 | 0.1094 | 0.1023 | 0.1380 | 0.5262 | 37 | 65 | 100 | 137 | 174 | 217 | 278 | 349 | 460 | 0.0040 | 34.98 | 6.397 | 0.3275 | 78453.6 | 37400000 | 21600000000 | 14300000000000 | 0.5030 | 0.1632 | 0.0118 | 0.0034 | 0.0686 | 0.0049 | 0.1902 | 0.0303 | 0.1873 | 0.0654 | 0.2000 | 0.1563 | 0.1490 | 0.1904 | 0.0961 | 0.1553 | 0.0696 | 0.1484 | 0.0275 | 0.2456 | 0.0003 | 0.0003 | 0.0010 | 0.0006 | 0.0045 | 0.0020 | 0.0170 | 0.0107 | 0.0701 | 0.0457 | 0.1114 | 0.0835 | 0.0947 | 0.0760 | 0.1218 | 0.0998 | 0.5791 | 0.6816 | 0.0000 | 0.0000 | 0.0048 | 0.0039 | 0.0064 | 0.0086 | 0.0301 | 0.0368 | 0.0924 | 0.1092 | 0.1557 | 0.1908 | 0.1090 | 0.1132 | 0.1557 | 0.1586 | 0.4458 | 0.3789 | 0.0009 | 0.0009 | 0.0035 | 0.0242 | 0.0797 | 0.1277 | 0.1035 | 0.1364 | 0.5234 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 993 | 394 | | 3513 | 2040 | 83.9 | 23.57 | 182.26 | 150.78 | 58 | 64 | 69 | 74 | 80 | 86 | 93 | 102 | 117 | 0.2098 | 428 | 0.610 | 126.40 | 36.89 | 1 | 0.1153 | 405 | 0.0023 | 17.58 | 6.355 | 0.2696 | 7588.6 | 740923 | 77800000 | 8750000000 | 0.4603 | 0.1930 | 0.0011 | 0.0000 | 0.0056 | 0.0007 | 0.0134 | 0.0026 | 0.0431 | 0.0082 | 0.0968 | 0.0264 | 0.1556 | 0.0541 | 0.1617 | 0.0463 | 0.1796 | 0.0825 | 0.3430 | 0.7792 | 0.0008 | 0.0000 | 0.0012 | 0.0003 | 0.0047 | 0.0003 | 0.0176 | 0.0029 | 0.0434 | 0.0159 | 0.0672 | 0.0308 | 0.0649 | 0.0238 | 0.0883 | 0.0443 | 0.7120 | 0.8816 | 0.0000 | 0.0059 | 0.0052 | 0.0059 | 0.0181 | 0.0265 | 0.0557 | 0.0649 | 0.0959 | 0.1150 | 0.1386 | 0.1593 | 0.1010 | 0.1062 | 0.1451 | 0.1386 | 0.4404 | 0.3776 | 0.0000 | 0.0059 | 0.0092 | 0.0301 | 0.0682 | 0.1009 | 0.0904 | 0.1193 | 0.5760 | 38 | 61 | 78 | 94 | 117 | 169 | 238 | 312 | 410 | 0.0064 | 25.03 | 5.822 | 0.3730 | 55941.1 | 22700000 | 10800000000 | 5710000000000 | 0.5146 | 0.1363 | 0.0251 | 0.0117 | 0.1967 | 0.0156 | 0.1799 | 0.0702 | 0.1674 | 0.1384 | 0.1632 | 0.2242 | 0.1297 | 0.1696 | 0.0795 | 0.1345 | 0.0418 | 0.1228 | 0.0167 | 0.1131 | 0.0011 | 0.0037 | 0.0055 | 0.0037 | 0.0033 | 0.0065 | 0.0199 | 0.0140 | 0.0719 | 0.0699 | 0.1062 | 0.0885 | 0.0752 | 0.0690 | 0.1195 | 0.1053 | 0.5973 | 0.6393 | 0.0000 | 0.0000 | 0.0015 | 0.0036 | 0.0075 | 0.0054 | 0.0256 | 0.0536 | 0.0902 | 0.1161 | 0.1504 | 0.1393 | 0.1158 | 0.1339 | 0.1504 | 0.1750 | 0.4586 | 0.3732 | 0.0000 | 0.0013 | 0.0051 | 0.0269 | 0.0654 | 0.1333 | 0.0885 | 0.1321 | 0.5474 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 477 | 250 | | 5842 | 6724 | 472.6 | 109.57 | 64.97 | 82.36 | 352 | 384 | 409 | 431 | 454 | 480 | 513 | 551 | 621 | 0.1120 | 753 | 1.059 | 127.44 | 46.01 | 1 | 0.0580 | 339 | 0.0010 | 46.76 | 7.191 | 0.1916 | 235384.0 | 124000000 | 68700000000 | 40200000000000 | 0.4185 | 0.2273 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0051 | 0.0000 | 0.0183 | 0.0015 | 0.0595 | 0.0197 | 0.1231 | 0.0436 | 0.1215 | 0.0347 | 0.1414 | 0.0528 | 0.5311 | 0.8478 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0061 | 0.0000 | 0.0303 | 0.0139 | 0.0654 | 0.0255 | 0.0629 | 0.0177 | 0.0794 | 0.0279 | 0.7550 | 0.9150 | 0.0020 | 0.0082 | 0.0049 | 0.0109 | 0.0225 | 0.0136 | 0.0470 | 0.0625 | 0.1136 | 0.1223 | 0.1185 | 0.1929 | 0.0803 | 0.0870 | 0.1156 | 0.1304 | 0.4956 | 0.3723 | 0.0012 | 0.0040 | 0.0064 | 0.0302 | 0.0770 | 0.1132 | 0.0870 | 0.1140 | 0.5671 | 5 | 7 | 9 | 13 | 27 | 45 | 76 | 118 | 187 | 0.0898 | 5.57 | 4.185 | 0.6123 | 11003.2 | 2590000 | 720000000 | 223000000000 | 0.5988 | 0.0846 | 0.0147 | 0.0063 | 0.0939 | 0.0135 | 0.2413 | 0.0387 | 0.1971 | 0.0729 | 0.1823 | 0.1674 | 0.1050 | 0.2115 | 0.0958 | 0.1476 | 0.0405 | 0.1611 | 0.0295 | 0.1809 | 0.0004 | 0.0025 | 0.0000 | 0.0011 | 0.0016 | 0.0035 | 0.0130 | 0.0074 | 0.0438 | 0.0337 | 0.0686 | 0.0561 | 0.0603 | 0.0459 | 0.0832 | 0.0775 | 0.7292 | 0.7724 | 0.0000 | 0.0000 | 0.0015 | 0.0046 | 0.0040 | 0.0040 | 0.0206 | 0.0259 | 0.0667 | 0.0856 | 0.1003 | 0.1086 | 0.0832 | 0.0851 | 0.1169 | 0.1132 | 0.6068 | 0.5730 | 0.0000 | 0.0000 | 0.0044 | 0.0146 | 0.0521 | 0.0838 | 0.0710 | 0.1094 | 0.6648 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 640 | 647 | | 6376 | 20211 | 467.1 | 97.26 | 74.59 | 104.47 | 355 | 384 | 407 | 429 | 451 | 477 | 504 | 541 | 602 | 0.0495 | 1000 | 0.965 | 107.82 | 31.58 | 1 | 0.0402 | 256 | 0.0008 | 48.43 | 7.332 | 0.1727 | 227685.0 | 116000000 | 61700000000 | 34200000000000 | 0.4323 | 0.2096 | 0.0005 | 0.0000 | 0.0005 | 0.0002 | 0.0030 | 0.0000 | 0.0118 | 0.0013 | 0.0469 | 0.0161 | 0.0999 | 0.0336 | 0.1154 | 0.0239 | 0.1501 | 0.0351 | 0.5720 | 0.8897 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0063 | 0.0002 | 0.0211 | 0.0111 | 0.0446 | 0.0196 | 0.0504 | 0.0108 | 0.0759 | 0.0166 | 0.7993 | 0.9416 | 0.0039 | 0.0000 | 0.0068 | 0.0084 | 0.0193 | 0.0169 | 0.0501 | 0.0478 | 0.1157 | 0.1348 | 0.1533 | 0.1573 | 0.0984 | 0.1152 | 0.1215 | 0.1348 | 0.4311 | 0.3848 | 0.0004 | 0.0014 | 0.0086 | 0.0280 | 0.0714 | 0.1288 | 0.1065 | 0.1352 | 0.5197 | 7 | 8 | 9 | 11 | 16 | 39 | 83 | 140 | 227 | 0.1404 | 11.27 | 4.303 | 0.6000 | 16476.9 | 5110000 | 1900000000 | 803000000000 | 0.4799 | 0.1508 | 0.0373 | 0.0004 | 0.1664 | 0.0126 | 0.2806 | 0.0605 | 0.1730 | 0.1438 | 0.1498 | 0.2138 | 0.1068 | 0.2197 | 0.0397 | 0.1363 | 0.0281 | 0.1023 | 0.0182 | 0.1106 | 0.0003 | 0.0001 | 0.0003 | 0.0006 | 0.0006 | 0.0010 | 0.0070 | 0.0080 | 0.0388 | 0.0338 | 0.0642 | 0.0584 | 0.0456 | 0.0429 | 0.0655 | 0.0588 | 0.7778 | 0.7963 | 0.0000 | 0.0010 | 0.0005 | 0.0002 | 0.0012 | 0.0013 | 0.0093 | 0.0155 | 0.0514 | 0.0530 | 0.0784 | 0.0890 | 0.0588 | 0.0718 | 0.0916 | 0.0918 | 0.7088 | 0.6764 | 0.0000 | 0.0000 | 0.0019 | 0.0069 | 0.0418 | 0.0702 | 0.0519 | 0.0787 | 0.7487 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 226 | 604 | | 4693 | 21436 | 383.8 | 76.01 | 185.02 | 221.64 | 284 | 313 | 337 | 360 | 381 | 402 | 425 | 454 | 486 | 0.0416 | 891 | 1.052 | 130.17 | 34.01 | 1 | 0.0641 | 301 | 0.0008 | 47.52 | 7.327 | 0.1592 | 153105.0 | 63300000 | 27000000000 | 11900000000000 | 0.3995 | 0.2470 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0023 | 0.0002 | 0.0165 | 0.0017 | 0.0621 | 0.0177 | 0.1229 | 0.0293 | 0.1371 | 0.0275 | 0.1688 | 0.0446 | 0.4889 | 0.8790 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0073 | 0.0015 | 0.0275 | 0.0148 | 0.0536 | 0.0238 | 0.0573 | 0.0171 | 0.0744 | 0.0278 | 0.7785 | 0.9150 | 0.0000 | 0.0000 | 0.0120 | 0.0000 | 0.0156 | 0.0000 | 0.0648 | 0.0000 | 0.1212 | 0.0000 | 0.1633 | 0.0000 | 0.1357 | 0.0000 | 0.1465 | 0.0000 | 0.3409 | 0.0000 | 0.0000 | 0.0009 | 0.0069 | 0.0221 | 0.0711 | 0.1111 | 0.0954 | 0.1176 | 0.5748 | 15 | 18 | 24 | 44 | 80 | 141 | 230 | 343 | 529 | 0.0288 | 19.62 | 5.529 | 0.4998 | 83352.2 | 50500000 | 35500000000 | 27500000000000 | 0.4199 | 0.2507 | 0.0207 | 0.0005 | 0.0995 | 0.0062 | 0.2392 | 0.0328 | 0.2041 | 0.0859 | 0.1593 | 0.1798 | 0.1282 | 0.2251 | 0.0610 | 0.1479 | 0.0518 | 0.1262 | 0.0362 | 0.1956 | 0.0004 | 0.0000 | 0.0006 | 0.0003 | 0.0016 | 0.0010 | 0.0080 | 0.0073 | 0.0421 | 0.0351 | 0.0732 | 0.0620 | 0.0459 | 0.0433 | 0.0727 | 0.0653 | 0.7556 | 0.7856 | 0.0000 | 0.0003 | 0.0009 | 0.0012 | 0.0020 | 0.0024 | 0.0131 | 0.0137 | 0.0524 | 0.0608 | 0.0851 | 0.0996 | 0.0622 | 0.0649 | 0.0907 | 0.0941 | 0.6935 | 0.6629 | 0.0001 | 0.0005 | 0.0023 | 0.0104 | 0.0496 | 0.0769 | 0.0547 | 0.0770 | 0.7284 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 705 | 883 | | 6676 | 9244 | 499.2 | 67.15 | 152.67 | 174.40 | 413 | 445 | 465 | 483 | 499 | 516 | 533 | 554 | 585 | 0.0900 | 832 | 1.232 | 101.42 | 42.43 | 1 | 0.0400 | 267 | 0.0009 | 54.50 | 7.284 | 0.1641 | 253716.0 | 131000000 | 68900000000 | 36800000000000 | 0.4286 | 0.2213 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0000 | 0.0060 | 0.0000 | 0.0214 | 0.0109 | 0.0488 | 0.0210 | 0.0590 | 0.0100 | 0.0846 | 0.0168 | 0.7780 | 0.9412 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0000 | 0.0136 | 0.0106 | 0.0283 | 0.0205 | 0.0247 | 0.0094 | 0.0369 | 0.0151 | 0.8931 | 0.9443 | 0.0165 | 0.0000 | 0.0412 | 0.0000 | 0.0576 | 0.0000 | 0.0864 | 0.0000 | 0.1358 | 0.0000 | 0.1296 | 0.0000 | 0.1276 | 0.0000 | 0.1379 | 0.0000 | 0.2675 | 0.0000 | 0.0018 | 0.0036 | 0.0083 | 0.0283 | 0.0676 | 0.1221 | 0.1140 | 0.1355 | 0.5189 | 19 | 26 | 37 | 53 | 74 | 110 | 169 | 273 | 415 | 0.0207 | 24.07 | 5.517 | 0.4810 | 53719.9 | 26700000 | 15900000000 | 10600000000000 | 0.4686 | 0.1593 | 0.0797 | 0.0005 | 0.2210 | 0.0235 | 0.2295 | 0.1208 | 0.1292 | 0.1504 | 0.1075 | 0.1711 | 0.0821 | 0.1602 | 0.0483 | 0.1022 | 0.0628 | 0.1203 | 0.0399 | 0.1509 | 0.0003 | 0.0002 | 0.0015 | 0.0005 | 0.0038 | 0.0027 | 0.0145 | 0.0131 | 0.0737 | 0.0515 | 0.1088 | 0.1038 | 0.0748 | 0.0620 | 0.1129 | 0.1048 | 0.6098 | 0.6614 | 0.0000 | 0.0000 | 0.0008 | 0.0035 | 0.0050 | 0.0039 | 0.0218 | 0.0226 | 0.0916 | 0.0960 | 0.1439 | 0.1633 | 0.0871 | 0.0886 | 0.1226 | 0.1363 | 0.5273 | 0.4859 | 0.0003 | 0.0003 | 0.0037 | 0.0141 | 0.0844 | 0.1335 | 0.0820 | 0.1187 | 0.5629 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 779 | 488 | | 1658 | 7515 | 661.2 | 127.45 | 21.12 | 72.35 | 472 | 534 | 588 | 636 | 672 | 708 | 749 | 791 | 831 | 0.0896 | 673 | 1.056 | 79.26 | 20.40 | 1 | 0.1128 | 187 | 0.0037 | 8.63 | 5.897 | 0.3770 | 453371.0 | 321000000 | 233000000000 | 172000000000000 | 0.3992 | 0.2328 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0029 | 0.0000 | 0.0098 | 0.0018 | 0.0479 | 0.0231 | 0.0685 | 0.0358 | 0.0607 | 0.0219 | 0.0881 | 0.0328 | 0.7202 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0018 | 0.0283 | 0.0231 | 0.0358 | 0.0358 | 0.0253 | 0.0219 | 0.0365 | 0.0328 | 0.8718 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0000 | 0.0344 | 0.0000 | 0.0531 | 0.0000 | 0.0531 | 0.0000 | 0.0688 | 0.0000 | 0.1000 | 0.0000 | 0.6781 | 0.0000 | 0.0011 | 0.0011 | 0.0034 | 0.0135 | 0.0270 | 0.0529 | 0.0450 | 0.0541 | 0.8018 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 12 | 17 | 0.1063 | 2.38 | 1.499 | 0.4250 | 5680.0 | 3330000 | 2380000000 | 1890000000000 | 0.4909 | 0.1207 | 0.0780 | 0.0610 | 0.2110 | 0.0749 | 0.2844 | 0.0999 | 0.2661 | 0.1207 | 0.0826 | 0.1914 | 0.0505 | 0.1692 | 0.0092 | 0.0874 | 0.0138 | 0.0707 | 0.0046 | 0.1248 | 0.0181 | 0.0352 | 0.0233 | 0.0424 | 0.0194 | 0.0488 | 0.0440 | 0.0456 | 0.0660 | 0.0697 | 0.0699 | 0.0689 | 0.0621 | 0.0817 | 0.0776 | 0.0961 | 0.6197 | 0.5116 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0054 | 0.0000 | 0.0090 | 0.0189 | 0.0667 | 0.0682 | 0.1189 | 0.0928 | 0.0360 | 0.0625 | 0.0811 | 0.0795 | 0.6829 | 0.6761 | 0.0016 | 0.0064 | 0.0096 | 0.0305 | 0.0595 | 0.0691 | 0.0740 | 0.0804 | 0.6688 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1030 | 654 | | 4733 | 10425 | 467.9 | 107.24 | 95.77 | 122.81 | 345 | 379 | 404 | 428 | 451 | 479 | 509 | 550 | 613 | 0.0706 | 736 | 0.617 | 150.66 | 41.15 | 1 | 0.0909 | 430 | 0.0008 | 55.01 | 7.358 | 0.1623 | 230448.0 | 120000000 | 65300000000 | 37500000000000 | 0.3787 | 0.2634 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0007 | 0.0134 | 0.0009 | 0.0647 | 0.0210 | 0.1390 | 0.0495 | 0.1451 | 0.0401 | 0.1678 | 0.0472 | 0.4677 | 0.8406 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0006 | 0.0057 | 0.0004 | 0.0302 | 0.0145 | 0.0629 | 0.0288 | 0.0577 | 0.0177 | 0.0847 | 0.0228 | 0.7570 | 0.9150 | 0.0023 | 0.0000 | 0.0070 | 0.0000 | 0.0151 | 0.0201 | 0.0568 | 0.0936 | 0.1230 | 0.1472 | 0.1647 | 0.2107 | 0.0974 | 0.1037 | 0.1334 | 0.1171 | 0.4002 | 0.3077 | 0.0005 | 0.0024 | 0.0063 | 0.0250 | 0.0794 | 0.1414 | 0.1034 | 0.1255 | 0.5161 | 8 | 10 | 12 | 16 | 31 | 66 | 119 | 187 | 269 | 0.0567 | 15.85 | 4.921 | 0.5294 | 24254.7 | 8620000 | 3790000000 | 1970000000000 | 0.5285 | 0.1189 | 0.0542 | 0.0020 | 0.2045 | 0.0127 | 0.3074 | 0.1029 | 0.1864 | 0.1470 | 0.1140 | 0.2238 | 0.0695 | 0.2285 | 0.0320 | 0.1142 | 0.0209 | 0.0788 | 0.0111 | 0.0902 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0003 | 0.0011 | 0.0095 | 0.0066 | 0.0504 | 0.0403 | 0.0831 | 0.0816 | 0.0652 | 0.0504 | 0.0967 | 0.0809 | 0.6944 | 0.7391 | 0.0000 | 0.0000 | 0.0013 | 0.0003 | 0.0019 | 0.0021 | 0.0107 | 0.0164 | 0.0630 | 0.0649 | 0.1047 | 0.1238 | 0.0740 | 0.0795 | 0.1160 | 0.1196 | 0.6286 | 0.5934 | 0.0000 | 0.0003 | 0.0014 | 0.0107 | 0.0546 | 0.0976 | 0.0658 | 0.1029 | 0.6668 | ||
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 211 | 348 | | 4562 | 14662 | 292.1 | 59.07 | 135.81 | 209.30 | 220 | 241 | 258 | 274 | 289 | 304 | 320 | 340 | 367 | 0.0645 | 945 | 0.932 | 136.85 | 50.12 | 1 | 0.0855 | 390 | 0.0007 | 74.36 | 7.435 | 0.1412 | 88808.4 | 28100000 | 9250000000 | 3170000000000 | 0.4402 | 0.2161 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0029 | 0.0000 | 0.0167 | 0.0014 | 0.0694 | 0.0171 | 0.1478 | 0.0364 | 0.1491 | 0.0316 | 0.1825 | 0.0583 | 0.4299 | 0.8552 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0018 | 0.0000 | 0.0071 | 0.0004 | 0.0325 | 0.0141 | 0.0723 | 0.0270 | 0.0621 | 0.0175 | 0.0948 | 0.0314 | 0.7283 | 0.9096 | 0.0085 | 0.0305 | 0.0142 | 0.0534 | 0.0355 | 0.0763 | 0.1050 | 0.1374 | 0.1475 | 0.1527 | 0.2014 | 0.1450 | 0.1078 | 0.1145 | 0.1362 | 0.1069 | 0.2440 | 0.1832 | 0.0009 | 0.0045 | 0.0095 | 0.0345 | 0.0971 | 0.1324 | 0.1261 | 0.1515 | 0.4435 | 11 | 12 | 14 | 17 | 22 | 47 | 116 | 250 | 458 | 0.0764 | 33.39 | 4.749 | 0.5335 | 62246.8 | 39200000 | 28700000000 | 23200000000000 | 0.5235 | 0.1167 | 0.0898 | 0.0014 | 0.2511 | 0.0304 | 0.2735 | 0.1824 | 0.1276 | 0.2041 | 0.1024 | 0.2020 | 0.0589 | 0.1399 | 0.0449 | 0.0878 | 0.0337 | 0.0662 | 0.0182 | 0.0858 | 0.0002 | 0.0002 | 0.0002 | 0.0002 | 0.0026 | 0.0024 | 0.0088 | 0.0086 | 0.0505 | 0.0448 | 0.0827 | 0.0772 | 0.0569 | 0.0558 | 0.0882 | 0.0792 | 0.7098 | 0.7318 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0021 | 0.0017 | 0.0094 | 0.0111 | 0.0555 | 0.0599 | 0.0916 | 0.1008 | 0.0699 | 0.0806 | 0.1010 | 0.1079 | 0.6706 | 0.6378 | 0.0002 | 0.0015 | 0.0015 | 0.0077 | 0.0503 | 0.0907 | 0.0609 | 0.0912 | 0.6961 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 216 | 528 | | 5345 | 6687 | 126.2 | 29.45 | 246.37 | 196.30 | 92 | 102 | 109 | 116 | 122 | 129 | 137 | 148 | 166 | 0.1069 | 715 | 0.821 | 98.35 | 24.08 | 1 | 0.0462 | 247 | 0.0025 | 20.42 | 6.327 | 0.2607 | 16786.6 | 2360000 | 350000000 | 54900000000 | 0.4217 | 0.2280 | 0.0006 | 0.0000 | 0.0020 | 0.0002 | 0.0049 | 0.0002 | 0.0260 | 0.0037 | 0.0795 | 0.0242 | 0.1393 | 0.0480 | 0.1549 | 0.0494 | 0.1980 | 0.0730 | 0.3948 | 0.8015 | 0.0002 | 0.0000 | 0.0014 | 0.0002 | 0.0025 | 0.0000 | 0.0114 | 0.0013 | 0.0377 | 0.0144 | 0.0616 | 0.0276 | 0.0705 | 0.0203 | 0.1045 | 0.0325 | 0.7102 | 0.9036 | 0.0065 | 0.0029 | 0.0043 | 0.0324 | 0.0293 | 0.0412 | 0.0759 | 0.1265 | 0.1605 | 0.1765 | 0.1811 | 0.1882 | 0.1215 | 0.1500 | 0.1443 | 0.1412 | 0.2766 | 0.1412 | 0.0037 | 0.0058 | 0.0146 | 0.0379 | 0.0853 | 0.1328 | 0.1087 | 0.1424 | 0.4688 | 29 | 68 | 108 | 156 | 206 | 258 | 323 | 400 | 511 | 0.0020 | 102.03 | 7.263 | 0.2296 | 99223.3 | 51700000 | 32100000000 | 22600000000000 | 0.4373 | 0.2354 | 0.0192 | 0.0026 | 0.0936 | 0.0096 | 0.1554 | 0.0379 | 0.1930 | 0.0889 | 0.1696 | 0.1612 | 0.1637 | 0.1886 | 0.0952 | 0.1468 | 0.0693 | 0.1476 | 0.0409 | 0.2169 | 0.0003 | 0.0010 | 0.0017 | 0.0010 | 0.0063 | 0.0027 | 0.0199 | 0.0129 | 0.0515 | 0.0493 | 0.1085 | 0.0818 | 0.0863 | 0.0592 | 0.1102 | 0.0896 | 0.6153 | 0.7027 | 0.0000 | 0.0000 | 0.0026 | 0.0055 | 0.0110 | 0.0197 | 0.0408 | 0.0466 | 0.0891 | 0.1102 | 0.1414 | 0.1694 | 0.1137 | 0.1190 | 0.1378 | 0.1464 | 0.4636 | 0.3832 | 0.0007 | 0.0028 | 0.0067 | 0.0245 | 0.0823 | 0.1199 | 0.0986 | 0.1341 | 0.5303 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 284 | 132 | | 3587 | 822 | 127.8 | 29.04 | 269.41 | 172.52 | 95 | 103 | 110 | 116 | 124 | 131 | 139 | 150 | 166 | 0.4538 | 373 | 0.730 | 52.80 | 16.97 | 1 | 0.0435 | 156 | 0.0026 | 19.75 | 6.264 | 0.2480 | 17172.9 | 2430000 | 364000000 | 57600000000 | 0.4499 | 0.2003 | 0.0013 | 0.0000 | 0.0039 | 0.0000 | 0.0057 | 0.0006 | 0.0284 | 0.0024 | 0.0900 | 0.0181 | 0.1429 | 0.0404 | 0.1608 | 0.0440 | 0.2172 | 0.0871 | 0.3497 | 0.8073 | 0.0007 | 0.0000 | 0.0031 | 0.0000 | 0.0021 | 0.0000 | 0.0106 | 0.0011 | 0.0398 | 0.0118 | 0.0621 | 0.0230 | 0.0648 | 0.0149 | 0.1204 | 0.0342 | 0.6964 | 0.9150 | 0.0048 | 0.0197 | 0.0207 | 0.0542 | 0.0287 | 0.0690 | 0.0813 | 0.1232 | 0.1643 | 0.1675 | 0.1978 | 0.1773 | 0.1372 | 0.1330 | 0.1547 | 0.1182 | 0.2105 | 0.1379 | 0.0025 | 0.0044 | 0.0176 | 0.0478 | 0.0806 | 0.1233 | 0.1296 | 0.1517 | 0.4424 | 69 | 114 | 153 | 190 | 229 | 286 | 352 | 427 | 520 | 0.0018 | 138.36 | 6.442 | 0.1434 | 102307.0 | 47200000 | 24500000000 | 13800000000000 | 0.3578 | 0.2281 | 0.0612 | 0.0059 | 0.2245 | 0.0413 | 0.3197 | 0.1150 | 0.1905 | 0.1475 | 0.1020 | 0.2448 | 0.0748 | 0.2035 | 0.0136 | 0.1091 | 0.0136 | 0.0973 | 0.0000 | 0.0354 | 0.0023 | 0.0018 | 0.0093 | 0.0161 | 0.0395 | 0.0233 | 0.0302 | 0.0376 | 0.1674 | 0.1485 | 0.2256 | 0.2093 | 0.1605 | 0.1503 | 0.1581 | 0.1807 | 0.2070 | 0.2326 | 0.0000 | 0.0045 | 0.0071 | 0.0227 | 0.0247 | 0.0455 | 0.0813 | 0.0818 | 0.2226 | 0.2682 | 0.2438 | 0.2182 | 0.1696 | 0.1591 | 0.1060 | 0.0682 | 0.1449 | 0.1318 | 0.0029 | 0.0086 | 0.0173 | 0.0490 | 0.1844 | 0.2478 | 0.1729 | 0.1499 | 0.1671 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1011 | 503 | | 8099 | 27715 | 207.4 | 49.29 | 90.32 | 133.45 | 151 | 164 | 175 | 187 | 199 | 212 | 228 | 248 | 276 | 0.0437 | 1212 | 1.109 | 152.01 | 45.19 | 2 | 0.0436 | 353 | 0.0011 | 36.08 | 7.089 | 0.1990 | 45423.4 | 10500000 | 2560000000 | 657000000000 | 0.4089 | 0.2364 | 0.0004 | 0.0000 | 0.0023 | 0.0001 | 0.0071 | 0.0004 | 0.0235 | 0.0021 | 0.0760 | 0.0188 | 0.1336 | 0.0422 | 0.1525 | 0.0391 | 0.1806 | 0.0611 | 0.4239 | 0.8362 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0001 | 0.0108 | 0.0006 | 0.0290 | 0.0107 | 0.0546 | 0.0216 | 0.0625 | 0.0137 | 0.0784 | 0.0235 | 0.7599 | 0.9297 | 0.0031 | 0.0101 | 0.0081 | 0.0067 | 0.0219 | 0.0236 | 0.0663 | 0.0809 | 0.1006 | 0.1720 | 0.1644 | 0.1585 | 0.1294 | 0.1282 | 0.1413 | 0.1619 | 0.3650 | 0.2580 | 0.0019 | 0.0022 | 0.0111 | 0.0259 | 0.0674 | 0.1078 | 0.1033 | 0.1236 | 0.5567 | 7 | 8 | 10 | 11 | 15 | 35 | 93 | 181 | 284 | 0.1964 | 12.37 | 4.050 | 0.6366 | 25966.7 | 10500000 | 5130000000 | 2920000000000 | 0.4760 | 0.1582 | 0.0839 | 0.0025 | 0.2737 | 0.0194 | 0.3606 | 0.1699 | 0.1380 | 0.2452 | 0.0745 | 0.2308 | 0.0467 | 0.1602 | 0.0182 | 0.0849 | 0.0044 | 0.0541 | 0.0000 | 0.0330 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0003 | 0.0003 | 0.0065 | 0.0072 | 0.0442 | 0.0379 | 0.0776 | 0.0649 | 0.0515 | 0.0468 | 0.0806 | 0.0673 | 0.7388 | 0.7756 | 0.0000 | 0.0001 | 0.0003 | 0.0006 | 0.0004 | 0.0007 | 0.0094 | 0.0113 | 0.0554 | 0.0601 | 0.1006 | 0.1144 | 0.0720 | 0.0756 | 0.1022 | 0.1029 | 0.6597 | 0.6343 | 0.0001 | 0.0000 | 0.0006 | 0.0064 | 0.0501 | 0.0888 | 0.0621 | 0.0936 | 0.6982 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1069 | 181 | | 1596 | 20629 | 124.5 | 28.67 | 72.87 | 146.49 | 98 | 102 | 107 | 111 | 116 | 122 | 130 | 143 | 162 | 0.0438 | 904 | 0.809 | 207.96 | 60.42 | 1 | 0.3440 | 549 | 0.0093 | 6.72 | 5.134 | 0.4357 | 16321.0 | 2270000 | 339000000 | 54100000000 | 0.4382 | 0.2050 | 0.0064 | 0.0000 | 0.0064 | 0.0000 | 0.0091 | 0.0000 | 0.0246 | 0.0027 | 0.0665 | 0.0317 | 0.0938 | 0.0661 | 0.1084 | 0.0465 | 0.1321 | 0.0715 | 0.5528 | 0.7815 | 0.0051 | 0.0000 | 0.0044 | 0.0000 | 0.0066 | 0.0000 | 0.0139 | 0.0025 | 0.0285 | 0.0257 | 0.0446 | 0.0426 | 0.0599 | 0.0238 | 0.0833 | 0.0401 | 0.7538 | 0.8653 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0111 | 0.0000 | 0.0406 | 0.0000 | 0.1144 | 0.0000 | 0.1476 | 0.0000 | 0.1144 | 0.0000 | 0.1255 | 0.0000 | 0.4428 | 0.0000 | 0.0016 | 0.0081 | 0.0049 | 0.0357 | 0.0535 | 0.1086 | 0.0729 | 0.1135 | 0.6013 | 7 | 9 | 11 | 12 | 13 | 15 | 19 | 61 | 281 | 0.2995 | 21.07 | 3.063 | 0.7088 | 26767.6 | 14200000 | 8950000000 | 6390000000000 | 0.3754 | 0.2426 | 0.1380 | 0.0048 | 0.3646 | 0.0530 | 0.2760 | 0.2133 | 0.1250 | 0.2337 | 0.0781 | 0.2422 | 0.0156 | 0.1627 | 0.0026 | 0.0590 | 0.0000 | 0.0217 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0005 | 0.0062 | 0.0050 | 0.0345 | 0.0311 | 0.0536 | 0.0493 | 0.0409 | 0.0369 | 0.0551 | 0.0516 | 0.8092 | 0.8256 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0018 | 0.0030 | 0.0082 | 0.0075 | 0.0356 | 0.0413 | 0.0757 | 0.0865 | 0.0522 | 0.0543 | 0.0707 | 0.0848 | 0.7559 | 0.7221 | 0.0000 | 0.0003 | 0.0008 | 0.0058 | 0.0340 | 0.0678 | 0.0421 | 0.0646 | 0.7846 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 454 | 777 | | 7409 | 17484 | 322.3 | 67.54 | 205.37 | 234.69 | 243 | 264 | 279 | 296 | 313 | 331 | 353 | 381 | 419 | 0.0565 | 988 | 1.214 | 100.09 | 46.32 | 1 | 0.0378 | 280 | 0.0005 | 88.54 | 7.749 | 0.1264 | 108444.0 | 38100000 | 13900000000 | 5270000000000 | 0.4118 | 0.2358 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0027 | 0.0000 | 0.0126 | 0.0013 | 0.0653 | 0.0133 | 0.1407 | 0.0324 | 0.1465 | 0.0319 | 0.1766 | 0.0542 | 0.4551 | 0.8669 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0040 | 0.0001 | 0.0306 | 0.0082 | 0.0657 | 0.0178 | 0.0679 | 0.0118 | 0.0977 | 0.0245 | 0.7329 | 0.9376 | 0.0029 | 0.0057 | 0.0029 | 0.0172 | 0.0155 | 0.0602 | 0.0472 | 0.0888 | 0.1282 | 0.1977 | 0.1643 | 0.1748 | 0.1157 | 0.1175 | 0.1400 | 0.1547 | 0.3832 | 0.1834 | 0.0024 | 0.0027 | 0.0054 | 0.0338 | 0.0764 | 0.1255 | 0.0940 | 0.1234 | 0.5364 | 11 | 14 | 17 | 31 | 88 | 192 | 303 | 420 | 566 | 0.0364 | 50.81 | 5.936 | 0.4194 | 97252.5 | 57300000 | 38200000000 | 27900000000000 | 0.4410 | 0.1792 | 0.0679 | 0.0012 | 0.2334 | 0.0148 | 0.3166 | 0.1561 | 0.1663 | 0.2149 | 0.0900 | 0.2129 | 0.0748 | 0.1752 | 0.0282 | 0.0907 | 0.0175 | 0.0767 | 0.0053 | 0.0576 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0013 | 0.0006 | 0.0070 | 0.0062 | 0.0449 | 0.0360 | 0.0791 | 0.0719 | 0.0574 | 0.0536 | 0.0936 | 0.0726 | 0.7161 | 0.7591 | 0.0000 | 0.0007 | 0.0007 | 0.0016 | 0.0023 | 0.0042 | 0.0126 | 0.0140 | 0.0555 | 0.0663 | 0.0963 | 0.1117 | 0.0864 | 0.0871 | 0.1164 | 0.1189 | 0.6299 | 0.5955 | 0.0003 | 0.0013 | 0.0012 | 0.0113 | 0.0518 | 0.0818 | 0.0742 | 0.1052 | 0.6728 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 503 | 432 | | 11808 | 33332 | 318.9 | 77.36 | 142.89 | 210.03 | 224 | 252 | 274 | 294 | 313 | 332 | 354 | 382 | 421 | 0.0347 | 1158 | 1.075 | 96.88 | 32.00 | 1 | 0.0204 | 241 | 0.0011 | 35.28 | 7.136 | 0.2018 | 107664.0 | 38400000 | 14400000000 | 5670000000000 | 0.4385 | 0.2096 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0068 | 0.0004 | 0.0240 | 0.0021 | 0.0823 | 0.0190 | 0.1435 | 0.0483 | 0.1432 | 0.0507 | 0.1608 | 0.0696 | 0.4388 | 0.8100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0071 | 0.0012 | 0.0317 | 0.0115 | 0.0656 | 0.0250 | 0.0600 | 0.0226 | 0.0788 | 0.0331 | 0.7553 | 0.9064 | 0.0047 | 0.0040 | 0.0064 | 0.0162 | 0.0180 | 0.0324 | 0.0588 | 0.1309 | 0.1171 | 0.1646 | 0.1656 | 0.2146 | 0.1257 | 0.1242 | 0.1416 | 0.1026 | 0.3621 | 0.2105 | 0.0020 | 0.0023 | 0.0069 | 0.0236 | 0.0705 | 0.1235 | 0.0941 | 0.1163 | 0.5608 | 6 | 7 | 9 | 11 | 20 | 67 | 166 | 292 | 458 | 0.1413 | 28.98 | 4.701 | 0.5652 | 64528.1 | 40100000 | 31100000000 | 29500000000000 | 0.4198 | 0.2297 | 0.0409 | 0.0008 | 0.1490 | 0.0130 | 0.2877 | 0.0770 | 0.1876 | 0.1317 | 0.1496 | 0.1991 | 0.0863 | 0.2098 | 0.0489 | 0.1278 | 0.0334 | 0.1018 | 0.0167 | 0.1390 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0007 | 0.0046 | 0.0041 | 0.0332 | 0.0264 | 0.0586 | 0.0502 | 0.0443 | 0.0368 | 0.0677 | 0.0562 | 0.7904 | 0.8252 | 0.0000 | 0.0002 | 0.0003 | 0.0008 | 0.0015 | 0.0014 | 0.0069 | 0.0086 | 0.0446 | 0.0485 | 0.0792 | 0.0935 | 0.0610 | 0.0660 | 0.0897 | 0.0966 | 0.7168 | 0.6842 | 0.0000 | 0.0006 | 0.0008 | 0.0069 | 0.0372 | 0.0677 | 0.0539 | 0.0771 | 0.7557 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 921 | 862 | | 6477 | 15065 | 403.9 | 109.37 | 121.63 | 165.75 | 277 | 309 | 337 | 363 | 389 | 418 | 449 | 490 | 551 | 0.0525 | 791 | 0.968 | 109.17 | 33.06 | 1 | 0.0426 | 276 | 0.0006 | 77.54 | 7.589 | 0.1419 | 175073.0 | 81300000 | 40400000000 | 21300000000000 | 0.4463 | 0.2101 | 0.0000 | 0.0000 | 0.0023 | 0.0000 | 0.0155 | 0.0004 | 0.0348 | 0.0028 | 0.1035 | 0.0244 | 0.1860 | 0.0559 | 0.1699 | 0.0627 | 0.1719 | 0.0842 | 0.3162 | 0.7696 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0023 | 0.0002 | 0.0093 | 0.0018 | 0.0399 | 0.0117 | 0.0837 | 0.0302 | 0.0747 | 0.0280 | 0.0983 | 0.0411 | 0.6910 | 0.8871 | 0.0029 | 0.0053 | 0.0174 | 0.0106 | 0.0101 | 0.0301 | 0.0702 | 0.0816 | 0.1259 | 0.1667 | 0.1802 | 0.1613 | 0.0948 | 0.1241 | 0.1324 | 0.1436 | 0.3661 | 0.2766 | 0.0003 | 0.0010 | 0.0055 | 0.0331 | 0.0776 | 0.1479 | 0.1117 | 0.1317 | 0.4912 | 7 | 9 | 13 | 25 | 47 | 84 | 137 | 215 | 339 | 0.0659 | 15.12 | 4.966 | 0.5541 | 42265.8 | 22000000 | 14400000000 | 10800000000000 | 0.3883 | 0.2650 | 0.0173 | 0.0015 | 0.0965 | 0.0090 | 0.2033 | 0.0324 | 0.1790 | 0.0799 | 0.1931 | 0.1735 | 0.1468 | 0.2123 | 0.0950 | 0.1508 | 0.0502 | 0.1388 | 0.0188 | 0.2017 | 0.0002 | 0.0002 | 0.0013 | 0.0011 | 0.0020 | 0.0012 | 0.0089 | 0.0089 | 0.0379 | 0.0318 | 0.0609 | 0.0533 | 0.0508 | 0.0440 | 0.0713 | 0.0640 | 0.7668 | 0.7956 | 0.0000 | 0.0003 | 0.0007 | 0.0005 | 0.0044 | 0.0032 | 0.0125 | 0.0119 | 0.0504 | 0.0631 | 0.0900 | 0.0998 | 0.0666 | 0.0700 | 0.0928 | 0.1054 | 0.6826 | 0.6458 | 0.0002 | 0.0002 | 0.0026 | 0.0098 | 0.0427 | 0.0786 | 0.0642 | 0.0823 | 0.7195 |