High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 211 | 348 | | 4562 | 14662 | 292.1 | 59.07 | 135.81 | 209.30 | 220 | 241 | 258 | 274 | 289 | 304 | 320 | 340 | 367 | 0.0645 | 945 | 0.932 | 136.85 | 50.12 | 1 | 0.0855 | 390 | 0.0007 | 74.36 | 7.435 | 0.1412 | 88808.4 | 28100000 | 9250000000 | 3170000000000 | 0.4402 | 0.2161 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0029 | 0.0000 | 0.0167 | 0.0014 | 0.0694 | 0.0171 | 0.1478 | 0.0364 | 0.1491 | 0.0316 | 0.1825 | 0.0583 | 0.4299 | 0.8552 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0018 | 0.0000 | 0.0071 | 0.0004 | 0.0325 | 0.0141 | 0.0723 | 0.0270 | 0.0621 | 0.0175 | 0.0948 | 0.0314 | 0.7283 | 0.9096 | 0.0085 | 0.0305 | 0.0142 | 0.0534 | 0.0355 | 0.0763 | 0.1050 | 0.1374 | 0.1475 | 0.1527 | 0.2014 | 0.1450 | 0.1078 | 0.1145 | 0.1362 | 0.1069 | 0.2440 | 0.1832 | 0.0009 | 0.0045 | 0.0095 | 0.0345 | 0.0971 | 0.1324 | 0.1261 | 0.1515 | 0.4435 | 11 | 12 | 14 | 17 | 22 | 47 | 116 | 250 | 458 | 0.0764 | 33.39 | 4.749 | 0.5335 | 62246.8 | 39200000 | 28700000000 | 23200000000000 | 0.5235 | 0.1167 | 0.0898 | 0.0014 | 0.2511 | 0.0304 | 0.2735 | 0.1824 | 0.1276 | 0.2041 | 0.1024 | 0.2020 | 0.0589 | 0.1399 | 0.0449 | 0.0878 | 0.0337 | 0.0662 | 0.0182 | 0.0858 | 0.0002 | 0.0002 | 0.0002 | 0.0002 | 0.0026 | 0.0024 | 0.0088 | 0.0086 | 0.0505 | 0.0448 | 0.0827 | 0.0772 | 0.0569 | 0.0558 | 0.0882 | 0.0792 | 0.7098 | 0.7318 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0021 | 0.0017 | 0.0094 | 0.0111 | 0.0555 | 0.0599 | 0.0916 | 0.1008 | 0.0699 | 0.0806 | 0.1010 | 0.1079 | 0.6706 | 0.6378 | 0.0002 | 0.0015 | 0.0015 | 0.0077 | 0.0503 | 0.0907 | 0.0609 | 0.0912 | 0.6961 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 230 | 289 | | 594 | 15656 | 100.5 | 15.06 | 36.01 | 54.50 | 85 | 89 | 91 | 94 | 96 | 100 | 105 | 110 | 120 | 0.0498 | 779 | 0.955 | 100.42 | 39.12 | 1 | 0.4916 | 292 | 0.0279 | 2.72 | 4.004 | 0.5272 | 10323.3 | 1090000 | 118000000 | 13200000000 | 0.4876 | 0.1693 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0017 | 0.0189 | 0.0156 | 0.0718 | 0.0469 | 0.1342 | 0.1267 | 0.0945 | 0.0729 | 0.1758 | 0.1181 | 0.4972 | 0.6181 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0034 | 0.0017 | 0.0136 | 0.0152 | 0.0560 | 0.0438 | 0.1070 | 0.1094 | 0.0594 | 0.0623 | 0.1171 | 0.0943 | 0.6435 | 0.6734 | 0.0167 | 0.0000 | 0.0000 | 0.0000 | 0.0500 | 0.0556 | 0.0667 | 0.0556 | 0.1333 | 0.2222 | 0.0833 | 0.3333 | 0.1500 | 0.0556 | 0.1500 | 0.1667 | 0.3500 | 0.1111 | 0.0080 | 0.0120 | 0.0279 | 0.0558 | 0.0996 | 0.0757 | 0.1235 | 0.1355 | 0.4622 | 7 | 9 | 11 | 13 | 15 | 19 | 26 | 43 | 94 | 0.1549 | 1.70 | 3.082 | 0.7448 | 4266.5 | 902121 | 242000000 | 74500000000 | 0.5337 | 0.1482 | 0.0320 | 0.0186 | 0.0756 | 0.0294 | 0.1496 | 0.0403 | 0.1676 | 0.0847 | 0.1746 | 0.1253 | 0.1652 | 0.1421 | 0.1216 | 0.1498 | 0.0889 | 0.1631 | 0.0249 | 0.2468 | 0.0064 | 0.0089 | 0.0093 | 0.0136 | 0.0091 | 0.0148 | 0.0209 | 0.0263 | 0.0483 | 0.0434 | 0.0699 | 0.0581 | 0.0665 | 0.0659 | 0.0883 | 0.0884 | 0.6813 | 0.6805 | 0.0016 | 0.0029 | 0.0045 | 0.0036 | 0.0103 | 0.0088 | 0.0251 | 0.0179 | 0.0527 | 0.0602 | 0.0730 | 0.0799 | 0.0685 | 0.0704 | 0.0894 | 0.0974 | 0.6749 | 0.6588 | 0.0038 | 0.0057 | 0.0085 | 0.0235 | 0.0569 | 0.0673 | 0.0687 | 0.0939 | 0.6715 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 837 | 568 | | 3810 | 7691 | 452.3 | 131.47 | 221.21 | 376.57 | 230 | 356 | 426 | 457 | 480 | 503 | 528 | 553 | 586 | 0.0787 | 605 | 1.031 | 95.27 | 22.00 | 2 | 0.0559 | 213 | 0.0026 | 14.07 | 6.352 | 0.2995 | 221894.0 | 114000000 | 60800000000 | 33200000000000 | 0.3620 | 0.2645 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0029 | 0.0000 | 0.0119 | 0.0016 | 0.0530 | 0.0188 | 0.0759 | 0.0350 | 0.0740 | 0.0220 | 0.1050 | 0.0373 | 0.6765 | 0.8854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0145 | 0.0142 | 0.0290 | 0.0275 | 0.0145 | 0.0133 | 0.0244 | 0.0245 | 0.9162 | 0.9198 | 0.0021 | 0.0000 | 0.0054 | 0.0122 | 0.0171 | 0.0000 | 0.0289 | 0.0427 | 0.0567 | 0.1037 | 0.0739 | 0.0732 | 0.1017 | 0.1220 | 0.1210 | 0.0793 | 0.5931 | 0.5671 | 0.0004 | 0.0017 | 0.0021 | 0.0084 | 0.0261 | 0.0433 | 0.0517 | 0.0685 | 0.7977 | 9 | 14 | 18 | 23 | 32 | 56 | 165 | 387 | 734 | 0.0801 | 36.23 | 4.662 | 0.5714 | 190720.0 | 231000000 | 326000000000 | 505000000000000 | 0.5310 | 0.1283 | 0.0284 | 0.0000 | 0.2074 | 0.0058 | 0.3466 | 0.0902 | 0.1307 | 0.1645 | 0.1392 | 0.2082 | 0.0881 | 0.2475 | 0.0256 | 0.1092 | 0.0227 | 0.0975 | 0.0114 | 0.0771 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0008 | 0.0089 | 0.0041 | 0.0491 | 0.0454 | 0.0930 | 0.0827 | 0.0637 | 0.0458 | 0.0885 | 0.0827 | 0.6963 | 0.7387 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0052 | 0.0017 | 0.0063 | 0.0112 | 0.0645 | 0.0730 | 0.1096 | 0.1162 | 0.0739 | 0.0691 | 0.1070 | 0.1072 | 0.6329 | 0.6199 | 0.0000 | 0.0005 | 0.0029 | 0.0082 | 0.0629 | 0.0936 | 0.0739 | 0.0975 | 0.6606 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 292 | 776 | | 6777 | 12524 | 325.6 | 51.91 | 172.85 | 222.30 | 258 | 277 | 296 | 311 | 323 | 337 | 352 | 369 | 393 | 0.0787 | 986 | 1.019 | 135.34 | 41.01 | 1 | 0.0484 | 328 | 0.0017 | 16.93 | 6.629 | 0.2646 | 108700.0 | 37200000 | 13000000000 | 4670000000000 | 0.3905 | 0.2545 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0036 | 0.0001 | 0.0131 | 0.0003 | 0.0300 | 0.0124 | 0.0571 | 0.0234 | 0.0742 | 0.0142 | 0.0991 | 0.0285 | 0.7210 | 0.9211 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0000 | 0.0071 | 0.0001 | 0.0167 | 0.0114 | 0.0295 | 0.0193 | 0.0326 | 0.0106 | 0.0443 | 0.0171 | 0.8660 | 0.9414 | 0.0057 | 0.0000 | 0.0114 | 0.0000 | 0.0341 | 0.0000 | 0.0994 | 0.0000 | 0.0994 | 0.0000 | 0.1605 | 0.0000 | 0.1179 | 0.0000 | 0.1264 | 0.0000 | 0.3452 | 0.0000 | 0.0015 | 0.0034 | 0.0073 | 0.0208 | 0.0531 | 0.0784 | 0.0815 | 0.1227 | 0.6313 | 14 | 16 | 19 | 25 | 51 | 113 | 215 | 343 | 515 | 0.0450 | 24.78 | 5.251 | 0.4914 | 79286.9 | 49200000 | 36500000000 | 31300000000000 | 0.4891 | 0.1521 | 0.0682 | 0.0006 | 0.2302 | 0.0144 | 0.3264 | 0.1428 | 0.1949 | 0.1888 | 0.1084 | 0.2199 | 0.0560 | 0.1929 | 0.0097 | 0.1180 | 0.0049 | 0.0760 | 0.0012 | 0.0466 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0015 | 0.0099 | 0.0101 | 0.0578 | 0.0482 | 0.0893 | 0.0778 | 0.0562 | 0.0523 | 0.0885 | 0.0782 | 0.6971 | 0.7317 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0023 | 0.0032 | 0.0138 | 0.0193 | 0.0706 | 0.0776 | 0.1115 | 0.1144 | 0.0701 | 0.0761 | 0.0996 | 0.1129 | 0.6310 | 0.5957 | 0.0000 | 0.0000 | 0.0012 | 0.0129 | 0.0628 | 0.1014 | 0.0584 | 0.0960 | 0.6673 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 338 | 385 | | 6192 | 19742 | 233.9 | 53.78 | 137.63 | 180.46 | 171 | 188 | 203 | 216 | 228 | 242 | 256 | 273 | 303 | 0.0555 | 1095 | 1.184 | 93.43 | 33.02 | 1 | 0.0363 | 225 | 0.0009 | 46.43 | 7.247 | 0.1652 | 57591.1 | 14900000 | 4100000000 | 1190000000000 | 0.3895 | 0.2646 | 0.0000 | 0.0000 | 0.0018 | 0.0002 | 0.0041 | 0.0002 | 0.0216 | 0.0019 | 0.0685 | 0.0188 | 0.1277 | 0.0445 | 0.1508 | 0.0419 | 0.1815 | 0.0664 | 0.4442 | 0.8263 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0002 | 0.0094 | 0.0011 | 0.0292 | 0.0133 | 0.0619 | 0.0277 | 0.0581 | 0.0198 | 0.0873 | 0.0284 | 0.7507 | 0.9093 | 0.0076 | 0.0147 | 0.0066 | 0.0265 | 0.0199 | 0.0265 | 0.0939 | 0.1088 | 0.1319 | 0.1559 | 0.1717 | 0.1706 | 0.1063 | 0.0971 | 0.1395 | 0.1294 | 0.3226 | 0.2706 | 0.0007 | 0.0025 | 0.0074 | 0.0298 | 0.0895 | 0.1288 | 0.1057 | 0.1541 | 0.4816 | 12 | 14 | 17 | 23 | 43 | 88 | 167 | 264 | 387 | 0.0461 | 28.23 | 5.244 | 0.4903 | 51505.6 | 27300000 | 17700000000 | 13300000000000 | 0.5436 | 0.1197 | 0.0589 | 0.0037 | 0.2135 | 0.0134 | 0.3305 | 0.1158 | 0.1622 | 0.1818 | 0.0910 | 0.2308 | 0.0773 | 0.1922 | 0.0344 | 0.1091 | 0.0245 | 0.0820 | 0.0077 | 0.0712 | 0.0000 | 0.0004 | 0.0004 | 0.0007 | 0.0018 | 0.0016 | 0.0103 | 0.0074 | 0.0488 | 0.0426 | 0.0827 | 0.0744 | 0.0564 | 0.0488 | 0.0887 | 0.0770 | 0.7108 | 0.7471 | 0.0003 | 0.0002 | 0.0010 | 0.0013 | 0.0015 | 0.0013 | 0.0126 | 0.0158 | 0.0614 | 0.0710 | 0.1023 | 0.1142 | 0.0737 | 0.0805 | 0.1031 | 0.1182 | 0.6440 | 0.5975 | 0.0002 | 0.0003 | 0.0017 | 0.0124 | 0.0554 | 0.0907 | 0.0685 | 0.0965 | 0.6744 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 382 | 242 | | 12664 | 34586 | 373.4 | 98.30 | 213.98 | 284.63 | 263 | 291 | 313 | 335 | 358 | 382 | 408 | 446 | 511 | 0.0376 | 1299 | 0.766 | 102.08 | 31.62 | 1 | 0.0237 | 300 | 0.0005 | 74.63 | 7.800 | 0.1485 | 149085.0 | 63700000 | 29200000000 | 14200000000000 | 0.4340 | 0.2186 | 0.0003 | 0.0001 | 0.0035 | 0.0000 | 0.0057 | 0.0011 | 0.0212 | 0.0027 | 0.0752 | 0.0188 | 0.1495 | 0.0375 | 0.1557 | 0.0407 | 0.1833 | 0.0594 | 0.4057 | 0.8397 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0016 | 0.0000 | 0.0071 | 0.0004 | 0.0383 | 0.0102 | 0.0764 | 0.0200 | 0.0727 | 0.0183 | 0.1055 | 0.0299 | 0.6974 | 0.9212 | 0.0052 | 0.0055 | 0.0048 | 0.0036 | 0.0180 | 0.0155 | 0.0557 | 0.0675 | 0.0894 | 0.1150 | 0.1198 | 0.1359 | 0.0802 | 0.1004 | 0.1066 | 0.1305 | 0.5202 | 0.4261 | 0.0011 | 0.0038 | 0.0108 | 0.0345 | 0.0819 | 0.1264 | 0.0936 | 0.1140 | 0.5339 | 10 | 14 | 21 | 42 | 78 | 144 | 249 | 393 | 629 | 0.0536 | 36.30 | 5.670 | 0.4778 | 126798.0 | 105000000 | 105000000000 | 118000000000000 | 0.3874 | 0.2464 | 0.0531 | 0.0011 | 0.1879 | 0.0093 | 0.2767 | 0.0927 | 0.1677 | 0.1537 | 0.1237 | 0.2297 | 0.0869 | 0.1936 | 0.0497 | 0.1194 | 0.0326 | 0.0973 | 0.0216 | 0.1031 | 0.0002 | 0.0002 | 0.0003 | 0.0005 | 0.0015 | 0.0010 | 0.0112 | 0.0071 | 0.0544 | 0.0452 | 0.0794 | 0.0732 | 0.0619 | 0.0524 | 0.0887 | 0.0799 | 0.7024 | 0.7405 | 0.0007 | 0.0001 | 0.0007 | 0.0009 | 0.0015 | 0.0024 | 0.0132 | 0.0185 | 0.0721 | 0.0749 | 0.1034 | 0.1143 | 0.0693 | 0.0766 | 0.1068 | 0.1115 | 0.6324 | 0.6008 | 0.0003 | 0.0004 | 0.0017 | 0.0125 | 0.0632 | 0.0921 | 0.0646 | 0.0980 | 0.6673 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 406 | 653 | | 9716 | 23603 | 431.9 | 88.96 | 349.44 | 405.84 | 326 | 380 | 406 | 425 | 442 | 459 | 475 | 495 | 525 | 0.0445 | 1051 | 1.155 | 114.98 | 44.01 | 1 | 0.0310 | 301 | 0.0009 | 57.02 | 7.395 | 0.1756 | 194415.0 | 90200000 | 42900000000 | 20900000000000 | 0.4256 | 0.2144 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0024 | 0.0002 | 0.0073 | 0.0009 | 0.0306 | 0.0101 | 0.0644 | 0.0220 | 0.0617 | 0.0172 | 0.1018 | 0.0289 | 0.7315 | 0.9207 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0014 | 0.0003 | 0.0115 | 0.0083 | 0.0248 | 0.0165 | 0.0200 | 0.0081 | 0.0331 | 0.0149 | 0.9091 | 0.9519 | 0.0122 | 0.0252 | 0.0157 | 0.0692 | 0.0332 | 0.0503 | 0.0752 | 0.1195 | 0.1461 | 0.2201 | 0.1785 | 0.1698 | 0.1400 | 0.0943 | 0.1417 | 0.1321 | 0.2572 | 0.1195 | 0.0002 | 0.0018 | 0.0031 | 0.0201 | 0.0458 | 0.0885 | 0.0915 | 0.1196 | 0.6294 | 11 | 15 | 26 | 74 | 177 | 311 | 477 | 692 | 979 | 0.0386 | 101.07 | 6.457 | 0.3962 | 286810.0 | 301000000 | 364000000000 | 491000000000000 | 0.5288 | 0.1335 | 0.0292 | 0.0023 | 0.1390 | 0.0075 | 0.2010 | 0.0674 | 0.1542 | 0.1168 | 0.1584 | 0.1632 | 0.1246 | 0.1791 | 0.0806 | 0.1344 | 0.0556 | 0.1290 | 0.0574 | 0.2002 | 0.0001 | 0.0001 | 0.0006 | 0.0003 | 0.0019 | 0.0007 | 0.0085 | 0.0046 | 0.0443 | 0.0358 | 0.0839 | 0.0706 | 0.0599 | 0.0519 | 0.0888 | 0.0796 | 0.7120 | 0.7564 | 0.0001 | 0.0003 | 0.0008 | 0.0014 | 0.0045 | 0.0043 | 0.0123 | 0.0170 | 0.0555 | 0.0621 | 0.1009 | 0.1122 | 0.0725 | 0.0814 | 0.1086 | 0.1185 | 0.6449 | 0.6027 | 0.0005 | 0.0014 | 0.0034 | 0.0121 | 0.0467 | 0.0905 | 0.0701 | 0.0917 | 0.6837 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 772 | 323 | | 794 | 7091 | 484.4 | 65.35 | 36.00 | 48.85 | 404 | 424 | 442 | 460 | 481 | 495 | 518 | 543 | 578 | 0.0636 | 451 | 0.996 | 53.60 | 13.89 | 2 | 0.1612 | 128 | 0.0034 | 13.68 | 5.871 | 0.2779 | 238955.0 | 120000000 | 61300000000 | 31900000000000 | 0.3670 | 0.2688 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0000 | 0.0000 | 0.0132 | 0.0038 | 0.0471 | 0.0315 | 0.0838 | 0.0693 | 0.0632 | 0.0290 | 0.0897 | 0.0453 | 0.7015 | 0.8212 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0092 | 0.0038 | 0.0330 | 0.0315 | 0.0607 | 0.0693 | 0.0356 | 0.0290 | 0.0567 | 0.0453 | 0.8047 | 0.8212 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0385 | 0.0000 | 0.0513 | 0.0000 | 0.0897 | 0.0000 | 0.1538 | 0.0000 | 0.0769 | 0.0000 | 0.1795 | 0.0000 | 0.4103 | 0.0000 | 0.0000 | 0.0000 | 0.0105 | 0.0210 | 0.0525 | 0.0787 | 0.0709 | 0.0787 | 0.6877 | 8 | 10 | 12 | 15 | 19 | 24 | 32 | 46 | 83 | 0.0654 | 8.26 | 3.794 | 0.6602 | 3682.1 | 710852 | 183000000 | 55400000000 | 0.4200 | 0.2030 | 0.0272 | 0.0084 | 0.0680 | 0.0199 | 0.1088 | 0.0383 | 0.1519 | 0.0577 | 0.1927 | 0.1013 | 0.1621 | 0.1448 | 0.1361 | 0.1401 | 0.0964 | 0.1758 | 0.0567 | 0.3137 | 0.0038 | 0.0044 | 0.0071 | 0.0076 | 0.0134 | 0.0126 | 0.0217 | 0.0199 | 0.0459 | 0.0354 | 0.0584 | 0.0527 | 0.0764 | 0.0594 | 0.0889 | 0.0916 | 0.6845 | 0.7164 | 0.0013 | 0.0032 | 0.0066 | 0.0056 | 0.0119 | 0.0071 | 0.0291 | 0.0333 | 0.0984 | 0.0881 | 0.0905 | 0.1079 | 0.0707 | 0.1000 | 0.1288 | 0.1087 | 0.5627 | 0.5460 | 0.0011 | 0.0069 | 0.0058 | 0.0185 | 0.0627 | 0.0801 | 0.0764 | 0.1091 | 0.6394 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 977 | 301 | | 13922 | 26863 | 211.1 | 59.41 | 243.85 | 302.54 | 140 | 161 | 177 | 191 | 205 | 221 | 237 | 258 | 290 | 0.0529 | 1421 | 0.517 | 152.46 | 33.12 | 3 | 0.0332 | 462 | 0.0010 | 40.05 | 7.158 | 0.1901 | 48082.9 | 11800000 | 3080000000 | 860000000000 | 0.4554 | 0.1927 | 0.0003 | 0.0000 | 0.0020 | 0.0002 | 0.0126 | 0.0010 | 0.0382 | 0.0033 | 0.1052 | 0.0256 | 0.1779 | 0.0652 | 0.1708 | 0.0702 | 0.1853 | 0.1080 | 0.3078 | 0.7265 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0019 | 0.0001 | 0.0091 | 0.0017 | 0.0405 | 0.0146 | 0.0746 | 0.0338 | 0.0714 | 0.0312 | 0.0998 | 0.0497 | 0.7024 | 0.8688 | 0.0033 | 0.0099 | 0.0092 | 0.0108 | 0.0191 | 0.0381 | 0.0654 | 0.1094 | 0.1325 | 0.1930 | 0.1822 | 0.1872 | 0.1190 | 0.0969 | 0.1457 | 0.1367 | 0.3236 | 0.2179 | 0.0009 | 0.0022 | 0.0066 | 0.0320 | 0.0904 | 0.1306 | 0.1036 | 0.1336 | 0.5001 | 8 | 10 | 14 | 35 | 97 | 203 | 327 | 486 | 702 | 0.0530 | 47.80 | 5.717 | 0.4211 | 150993.0 | 122000000 | 114000000000 | 121000000000000 | 0.4350 | 0.2316 | 0.0406 | 0.0021 | 0.1879 | 0.0150 | 0.2563 | 0.1084 | 0.1660 | 0.1540 | 0.1487 | 0.1826 | 0.0976 | 0.1847 | 0.0579 | 0.1280 | 0.0269 | 0.1004 | 0.0182 | 0.1248 | 0.0001 | 0.0000 | 0.0006 | 0.0003 | 0.0014 | 0.0012 | 0.0074 | 0.0074 | 0.0475 | 0.0377 | 0.0763 | 0.0659 | 0.0613 | 0.0479 | 0.0889 | 0.0735 | 0.7164 | 0.7660 | 0.0003 | 0.0001 | 0.0006 | 0.0004 | 0.0025 | 0.0033 | 0.0148 | 0.0202 | 0.0626 | 0.0746 | 0.1137 | 0.1211 | 0.0770 | 0.0770 | 0.1055 | 0.1172 | 0.6229 | 0.5861 | 0.0001 | 0.0008 | 0.0026 | 0.0105 | 0.0553 | 0.0925 | 0.0698 | 0.1031 | 0.6653 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 474 | 145 | | 2157 | 11213 | 221.6 | 78.59 | 65.05 | 137.53 | 132 | 156 | 176 | 192 | 207 | 222 | 245 | 295 | 349 | 0.0538 | 603 | 0.725 | 94.64 | 21.02 | 1 | 0.1136 | 245 | 0.0010 | 66.86 | 7.099 | 0.1610 | 55259.5 | 15300000 | 4580000000 | 1470000000000 | 0.4001 | 0.2354 | 0.0011 | 0.0000 | 0.0000 | 0.0013 | 0.0064 | 0.0032 | 0.0416 | 0.0121 | 0.0928 | 0.0490 | 0.1738 | 0.0732 | 0.1525 | 0.0803 | 0.1514 | 0.0968 | 0.3806 | 0.6841 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0027 | 0.0010 | 0.0148 | 0.0073 | 0.0425 | 0.0250 | 0.0748 | 0.0374 | 0.0742 | 0.0421 | 0.0883 | 0.0525 | 0.7026 | 0.8341 | 0.0055 | 0.0028 | 0.0037 | 0.0000 | 0.0073 | 0.0085 | 0.0147 | 0.0312 | 0.0569 | 0.0708 | 0.0734 | 0.1246 | 0.0477 | 0.1161 | 0.0734 | 0.1161 | 0.7174 | 0.5297 | 0.0000 | 0.0092 | 0.0035 | 0.0403 | 0.0909 | 0.0967 | 0.0748 | 0.0748 | 0.6099 | 12 | 14 | 15 | 17 | 18 | 20 | 25 | 45 | 176 | 0.1489 | 17.64 | 3.226 | 0.6746 | 23145.6 | 15600000 | 14100000000 | 15200000000000 | 0.6928 | 0.0672 | 0.0631 | 0.0192 | 0.1329 | 0.0266 | 0.2691 | 0.0932 | 0.2060 | 0.1391 | 0.1761 | 0.1953 | 0.1030 | 0.1982 | 0.0399 | 0.1450 | 0.0100 | 0.1109 | 0.0000 | 0.0725 | 0.0000 | 0.0037 | 0.0009 | 0.0029 | 0.0023 | 0.0054 | 0.0089 | 0.0125 | 0.0455 | 0.0432 | 0.0829 | 0.0602 | 0.0590 | 0.0557 | 0.0890 | 0.0798 | 0.7113 | 0.7366 | 0.0000 | 0.0000 | 0.0005 | 0.0006 | 0.0016 | 0.0023 | 0.0104 | 0.0116 | 0.0595 | 0.0687 | 0.1075 | 0.1167 | 0.0797 | 0.0797 | 0.1151 | 0.1358 | 0.6258 | 0.5846 | 0.0000 | 0.0010 | 0.0005 | 0.0090 | 0.0562 | 0.0853 | 0.0693 | 0.1094 | 0.6692 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 872 | 575 | | 6042 | 12072 | 101.1 | 29.15 | 201.53 | 223.69 | 69 | 77 | 84 | 91 | 97 | 103 | 110 | 120 | 139 | 0.0696 | 840 | 0.813 | 79.88 | 25.94 | 1 | 0.0386 | 233 | 0.0015 | 30.07 | 6.806 | 0.2198 | 11069.0 | 1320000 | 170000000 | 23900000000 | 0.4862 | 0.1865 | 0.0018 | 0.0002 | 0.0053 | 0.0006 | 0.0143 | 0.0023 | 0.0289 | 0.0069 | 0.0949 | 0.0296 | 0.1530 | 0.0590 | 0.1434 | 0.0611 | 0.1755 | 0.0846 | 0.3829 | 0.7558 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0024 | 0.0005 | 0.0109 | 0.0028 | 0.0454 | 0.0160 | 0.0803 | 0.0329 | 0.0748 | 0.0325 | 0.1071 | 0.0463 | 0.6782 | 0.8690 | 0.0043 | 0.0000 | 0.0017 | 0.0123 | 0.0112 | 0.0334 | 0.0543 | 0.0598 | 0.1422 | 0.1652 | 0.1716 | 0.1845 | 0.1112 | 0.1037 | 0.1362 | 0.1564 | 0.3672 | 0.2847 | 0.0008 | 0.0053 | 0.0162 | 0.0442 | 0.0797 | 0.1330 | 0.1035 | 0.1300 | 0.4873 | 18 | 30 | 47 | 67 | 108 | 171 | 253 | 356 | 517 | 0.0128 | 34.28 | 6.003 | 0.4255 | 90647.1 | 57700000 | 45300000000 | 41800000000000 | 0.5238 | 0.1388 | 0.0299 | 0.0012 | 0.1106 | 0.0112 | 0.2542 | 0.0630 | 0.1719 | 0.1064 | 0.1356 | 0.1694 | 0.1203 | 0.2041 | 0.0759 | 0.1291 | 0.0581 | 0.1283 | 0.0436 | 0.1873 | 0.0002 | 0.0003 | 0.0012 | 0.0009 | 0.0024 | 0.0014 | 0.0120 | 0.0077 | 0.0503 | 0.0456 | 0.0918 | 0.0772 | 0.0637 | 0.0548 | 0.0892 | 0.0894 | 0.6892 | 0.7227 | 0.0008 | 0.0000 | 0.0005 | 0.0016 | 0.0040 | 0.0062 | 0.0171 | 0.0230 | 0.0656 | 0.0792 | 0.1207 | 0.1321 | 0.0874 | 0.0879 | 0.1189 | 0.1252 | 0.5850 | 0.5447 | 0.0005 | 0.0016 | 0.0021 | 0.0115 | 0.0607 | 0.1004 | 0.0736 | 0.1068 | 0.6429 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1146 | 391 | | 12697 | 38415 | 310.0 | 92.49 | 153.57 | 202.77 | 205 | 234 | 255 | 274 | 295 | 319 | 346 | 384 | 440 | 0.0394 | 1513 | 0.946 | 124.09 | 49.52 | 3 | 0.0296 | 376 | 0.0009 | 41.44 | 7.326 | 0.1956 | 104638.0 | 38300000 | 15100000000 | 6390000000000 | 0.4357 | 0.2157 | 0.0002 | 0.0000 | 0.0023 | 0.0003 | 0.0069 | 0.0013 | 0.0281 | 0.0029 | 0.1035 | 0.0300 | 0.1722 | 0.0701 | 0.1505 | 0.0612 | 0.1633 | 0.0843 | 0.3731 | 0.7500 | 0.0001 | 0.0000 | 0.0015 | 0.0003 | 0.0028 | 0.0007 | 0.0089 | 0.0013 | 0.0404 | 0.0164 | 0.0715 | 0.0341 | 0.0623 | 0.0255 | 0.0826 | 0.0378 | 0.7299 | 0.8841 | 0.0017 | 0.0022 | 0.0045 | 0.0058 | 0.0083 | 0.0145 | 0.0403 | 0.0608 | 0.1026 | 0.1398 | 0.1520 | 0.2013 | 0.0911 | 0.1043 | 0.1273 | 0.1521 | 0.4720 | 0.3193 | 0.0016 | 0.0023 | 0.0054 | 0.0291 | 0.0756 | 0.1167 | 0.0885 | 0.1148 | 0.5659 | 7 | 9 | 11 | 17 | 46 | 106 | 192 | 307 | 462 | 0.0898 | 34.20 | 5.290 | 0.4957 | 64699.3 | 36300000 | 24200000000 | 18400000000000 | 0.3650 | 0.2639 | 0.0547 | 0.0028 | 0.2149 | 0.0156 | 0.2794 | 0.1388 | 0.1508 | 0.1713 | 0.1178 | 0.1966 | 0.0866 | 0.1720 | 0.0420 | 0.1084 | 0.0341 | 0.0926 | 0.0196 | 0.1020 | 0.0001 | 0.0002 | 0.0001 | 0.0004 | 0.0008 | 0.0006 | 0.0081 | 0.0072 | 0.0485 | 0.0397 | 0.0847 | 0.0723 | 0.0563 | 0.0480 | 0.0892 | 0.0718 | 0.7122 | 0.7599 | 0.0000 | 0.0002 | 0.0003 | 0.0007 | 0.0015 | 0.0026 | 0.0125 | 0.0167 | 0.0667 | 0.0735 | 0.1084 | 0.1144 | 0.0679 | 0.0763 | 0.1080 | 0.1128 | 0.6346 | 0.6028 | 0.0000 | 0.0003 | 0.0014 | 0.0088 | 0.0599 | 0.0938 | 0.0662 | 0.0996 | 0.6699 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 610 | 740 | | 10995 | 21735 | 347.4 | 98.02 | 165.63 | 275.68 | 237 | 265 | 287 | 309 | 330 | 354 | 385 | 424 | 482 | 0.0543 | 1180 | 0.823 | 156.77 | 42.94 | 1 | 0.0379 | 417 | 0.0006 | 76.46 | 7.762 | 0.1421 | 130306.0 | 52800000 | 23000000000 | 10800000000000 | 0.4099 | 0.2391 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0050 | 0.0004 | 0.0293 | 0.0030 | 0.0976 | 0.0224 | 0.1934 | 0.0609 | 0.1532 | 0.0578 | 0.1697 | 0.0815 | 0.3511 | 0.7739 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0001 | 0.0100 | 0.0014 | 0.0366 | 0.0128 | 0.0819 | 0.0266 | 0.0642 | 0.0246 | 0.0880 | 0.0371 | 0.7185 | 0.8974 | 0.0021 | 0.0038 | 0.0037 | 0.0104 | 0.0099 | 0.0133 | 0.0489 | 0.0579 | 0.1039 | 0.1670 | 0.1691 | 0.2201 | 0.1158 | 0.0911 | 0.1404 | 0.1670 | 0.4064 | 0.2695 | 0.0002 | 0.0032 | 0.0077 | 0.0270 | 0.0753 | 0.1302 | 0.0823 | 0.1115 | 0.5626 | 7 | 9 | 11 | 13 | 23 | 59 | 139 | 282 | 558 | 0.1212 | 27.49 | 4.518 | 0.5579 | 103430.0 | 90600000 | 93300000000 | 107000000000000 | 0.5655 | 0.1379 | 0.0639 | 0.0036 | 0.1916 | 0.0216 | 0.2652 | 0.1161 | 0.1568 | 0.1490 | 0.1285 | 0.1970 | 0.0930 | 0.1954 | 0.0558 | 0.1189 | 0.0323 | 0.1029 | 0.0129 | 0.0953 | 0.0002 | 0.0003 | 0.0003 | 0.0003 | 0.0008 | 0.0007 | 0.0092 | 0.0067 | 0.0505 | 0.0462 | 0.0921 | 0.0768 | 0.0586 | 0.0549 | 0.0894 | 0.0845 | 0.6990 | 0.7296 | 0.0004 | 0.0002 | 0.0007 | 0.0000 | 0.0020 | 0.0010 | 0.0127 | 0.0148 | 0.0665 | 0.0758 | 0.1061 | 0.1131 | 0.0700 | 0.0705 | 0.1023 | 0.1056 | 0.6393 | 0.6190 | 0.0003 | 0.0007 | 0.0012 | 0.0100 | 0.0608 | 0.1027 | 0.0621 | 0.0993 | 0.6629 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 534 | 923 | | 4850 | 8622 | 162.0 | 44.63 | 180.98 | 189.76 | 115 | 127 | 136 | 144 | 153 | 163 | 176 | 194 | 220 | 0.0923 | 796 | 1.107 | 100.01 | 36.69 | 1 | 0.0542 | 263 | 0.0016 | 35.56 | 6.803 | 0.2042 | 28220.0 | 5320000 | 1090000000 | 244000000000 | 0.4589 | 0.1995 | 0.0007 | 0.0000 | 0.0029 | 0.0005 | 0.0119 | 0.0016 | 0.0353 | 0.0018 | 0.0965 | 0.0224 | 0.1780 | 0.0576 | 0.1567 | 0.0576 | 0.1780 | 0.0908 | 0.3401 | 0.7676 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0024 | 0.0000 | 0.0113 | 0.0004 | 0.0464 | 0.0146 | 0.0848 | 0.0310 | 0.0754 | 0.0240 | 0.1095 | 0.0437 | 0.6690 | 0.8863 | 0.0021 | 0.0124 | 0.0095 | 0.0173 | 0.0148 | 0.0173 | 0.0674 | 0.0990 | 0.1349 | 0.1708 | 0.1802 | 0.1931 | 0.1117 | 0.0990 | 0.1454 | 0.1411 | 0.3340 | 0.2500 | 0.0025 | 0.0020 | 0.0129 | 0.0373 | 0.0821 | 0.1318 | 0.1035 | 0.1274 | 0.5005 | 14 | 24 | 41 | 71 | 110 | 159 | 230 | 325 | 469 | 0.0065 | 92.57 | 6.832 | 0.2972 | 68756.7 | 35000000 | 20900000000 | 13800000000000 | 0.4654 | 0.1787 | 0.0372 | 0.0015 | 0.1157 | 0.0126 | 0.2314 | 0.0576 | 0.2038 | 0.0919 | 0.1826 | 0.1859 | 0.1210 | 0.2273 | 0.0605 | 0.1485 | 0.0297 | 0.1348 | 0.0180 | 0.1399 | 0.0011 | 0.0005 | 0.0019 | 0.0018 | 0.0057 | 0.0016 | 0.0164 | 0.0127 | 0.0655 | 0.0540 | 0.0911 | 0.0881 | 0.0668 | 0.0623 | 0.0898 | 0.0865 | 0.6617 | 0.6924 | 0.0018 | 0.0000 | 0.0015 | 0.0081 | 0.0066 | 0.0098 | 0.0239 | 0.0242 | 0.0668 | 0.0752 | 0.1146 | 0.1134 | 0.0856 | 0.0935 | 0.1050 | 0.1143 | 0.5942 | 0.5616 | 0.0003 | 0.0028 | 0.0070 | 0.0215 | 0.0579 | 0.0958 | 0.0730 | 0.1078 | 0.6339 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 141 | 279 | | 6550 | 28560 | 325.2 | 76.94 | 118.00 | 205.38 | 229 | 259 | 281 | 299 | 318 | 339 | 361 | 391 | 431 | 0.0380 | 1086 | 1.019 | 88.10 | 26.68 | 3 | 0.0337 | 221 | 0.0007 | 63.80 | 7.487 | 0.1467 | 111704.0 | 40400000 | 15300000000 | 6070000000000 | 0.4422 | 0.2121 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0067 | 0.0012 | 0.0248 | 0.0030 | 0.0781 | 0.0206 | 0.1554 | 0.0495 | 0.1682 | 0.0513 | 0.1992 | 0.0834 | 0.3659 | 0.7909 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0003 | 0.0069 | 0.0006 | 0.0339 | 0.0127 | 0.0714 | 0.0286 | 0.0678 | 0.0219 | 0.0992 | 0.0413 | 0.7200 | 0.8945 | 0.0053 | 0.0096 | 0.0114 | 0.0288 | 0.0220 | 0.0745 | 0.0676 | 0.0962 | 0.1277 | 0.1923 | 0.1634 | 0.1635 | 0.1087 | 0.1130 | 0.1664 | 0.1394 | 0.3275 | 0.1827 | 0.0010 | 0.0043 | 0.0085 | 0.0299 | 0.0768 | 0.1404 | 0.1063 | 0.1358 | 0.4970 | 7 | 9 | 10 | 12 | 16 | 29 | 83 | 200 | 398 | 0.1579 | 24.15 | 4.168 | 0.5959 | 56105.0 | 38900000 | 32800000000 | 31500000000000 | 0.4719 | 0.1982 | 0.0778 | 0.0031 | 0.2645 | 0.0291 | 0.3497 | 0.1507 | 0.1482 | 0.1884 | 0.0819 | 0.2342 | 0.0426 | 0.1740 | 0.0180 | 0.0983 | 0.0098 | 0.0746 | 0.0074 | 0.0478 | 0.0000 | 0.0001 | 0.0004 | 0.0002 | 0.0004 | 0.0003 | 0.0067 | 0.0067 | 0.0467 | 0.0397 | 0.0880 | 0.0720 | 0.0536 | 0.0512 | 0.0899 | 0.0787 | 0.7143 | 0.7511 | 0.0001 | 0.0003 | 0.0004 | 0.0012 | 0.0016 | 0.0016 | 0.0092 | 0.0145 | 0.0557 | 0.0597 | 0.1096 | 0.1123 | 0.0663 | 0.0794 | 0.1060 | 0.1115 | 0.6510 | 0.6194 | 0.0000 | 0.0001 | 0.0019 | 0.0094 | 0.0525 | 0.0917 | 0.0654 | 0.0947 | 0.6842 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 171 | 227 | | 13156 | 26560 | 216.3 | 55.08 | 143.33 | 196.83 | 147 | 172 | 189 | 203 | 217 | 231 | 246 | 263 | 286 | 0.0570 | 1514 | 0.695 | 170.21 | 47.54 | 3 | 0.0364 | 479 | 0.0008 | 42.66 | 7.414 | 0.1765 | 49810.3 | 12100000 | 3040000000 | 797000000000 | 0.4175 | 0.2260 | 0.0007 | 0.0001 | 0.0014 | 0.0001 | 0.0076 | 0.0009 | 0.0228 | 0.0052 | 0.0655 | 0.0153 | 0.1188 | 0.0349 | 0.1344 | 0.0418 | 0.1753 | 0.0659 | 0.4735 | 0.8359 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0004 | 0.0075 | 0.0020 | 0.0220 | 0.0098 | 0.0398 | 0.0182 | 0.0480 | 0.0148 | 0.0644 | 0.0241 | 0.8168 | 0.9308 | 0.0028 | 0.0282 | 0.0118 | 0.0267 | 0.0277 | 0.0847 | 0.0602 | 0.1278 | 0.0906 | 0.1798 | 0.1387 | 0.1575 | 0.1280 | 0.1189 | 0.1505 | 0.1218 | 0.3898 | 0.1545 | 0.0012 | 0.0034 | 0.0079 | 0.0230 | 0.0477 | 0.0880 | 0.0938 | 0.1052 | 0.6296 | 16 | 19 | 22 | 26 | 40 | 80 | 154 | 256 | 424 | 0.0499 | 24.57 | 5.020 | 0.5076 | 59283.3 | 35800000 | 26400000000 | 22500000000000 | 0.6077 | 0.0916 | 0.0465 | 0.0024 | 0.1573 | 0.0221 | 0.2370 | 0.0945 | 0.1899 | 0.1299 | 0.1567 | 0.1853 | 0.1107 | 0.1877 | 0.0559 | 0.1296 | 0.0288 | 0.1216 | 0.0172 | 0.1270 | 0.0004 | 0.0003 | 0.0007 | 0.0014 | 0.0025 | 0.0019 | 0.0149 | 0.0139 | 0.0556 | 0.0499 | 0.0753 | 0.0693 | 0.0592 | 0.0511 | 0.0899 | 0.0801 | 0.7015 | 0.7321 | 0.0005 | 0.0015 | 0.0016 | 0.0014 | 0.0046 | 0.0059 | 0.0219 | 0.0234 | 0.0658 | 0.0751 | 0.1028 | 0.1190 | 0.0811 | 0.0870 | 0.1118 | 0.1202 | 0.6099 | 0.5665 | 0.0007 | 0.0013 | 0.0027 | 0.0190 | 0.0556 | 0.0905 | 0.0669 | 0.0992 | 0.6642 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 547 | 289 | | 11285 | 27072 | 244.5 | 58.73 | 197.38 | 232.26 | 172 | 193 | 209 | 224 | 239 | 255 | 274 | 296 | 325 | 0.0436 | 1181 | 1.186 | 113.74 | 45.89 | 1 | 0.0262 | 296 | 0.0006 | 59.04 | 7.598 | 0.1608 | 63242.6 | 17200000 | 4920000000 | 1470000000000 | 0.4595 | 0.1977 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0003 | 0.0222 | 0.0030 | 0.0838 | 0.0183 | 0.1665 | 0.0428 | 0.1519 | 0.0447 | 0.1695 | 0.0687 | 0.4015 | 0.8221 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0009 | 0.0000 | 0.0056 | 0.0015 | 0.0329 | 0.0117 | 0.0689 | 0.0232 | 0.0624 | 0.0202 | 0.0836 | 0.0302 | 0.7454 | 0.9132 | 0.0042 | 0.0118 | 0.0042 | 0.0251 | 0.0161 | 0.0340 | 0.0589 | 0.0991 | 0.1158 | 0.1731 | 0.1866 | 0.1864 | 0.1001 | 0.1080 | 0.1387 | 0.1391 | 0.3753 | 0.2234 | 0.0010 | 0.0019 | 0.0079 | 0.0250 | 0.0784 | 0.1238 | 0.0992 | 0.1291 | 0.5338 | 14 | 18 | 26 | 48 | 94 | 162 | 255 | 375 | 541 | 0.0240 | 59.33 | 6.100 | 0.4045 | 92900.8 | 59800000 | 46700000000 | 42500000000000 | 0.3821 | 0.2440 | 0.0415 | 0.0013 | 0.1747 | 0.0119 | 0.3178 | 0.1184 | 0.1407 | 0.1403 | 0.1199 | 0.1896 | 0.0884 | 0.1946 | 0.0465 | 0.1232 | 0.0336 | 0.1013 | 0.0369 | 0.1196 | 0.0001 | 0.0002 | 0.0000 | 0.0003 | 0.0009 | 0.0010 | 0.0080 | 0.0057 | 0.0480 | 0.0394 | 0.0973 | 0.0776 | 0.0603 | 0.0509 | 0.0905 | 0.0756 | 0.6949 | 0.7492 | 0.0002 | 0.0004 | 0.0020 | 0.0014 | 0.0027 | 0.0026 | 0.0159 | 0.0171 | 0.0664 | 0.0775 | 0.1207 | 0.1335 | 0.0813 | 0.0857 | 0.1106 | 0.1232 | 0.6001 | 0.5585 | 0.0001 | 0.0006 | 0.0019 | 0.0122 | 0.0586 | 0.1142 | 0.0705 | 0.1007 | 0.6412 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1179 | 272 | | 484 | 417 | 15.1 | 6.24 | 5.44 | 2.42 | 10 | 11 | 12 | 12 | 13 | 15 | 16 | 18 | 23 | 0.4964 | 207 | 0.834 | 37.74 | 12.04 | 0 | 0.2397 | 116 | 0.0096 | 14.01 | 4.972 | 0.3037 | 265.5 | 5621.95 | 142364 | 4170000 | 0.3690 | 0.2458 | 0.0041 | 0.0000 | 0.0207 | 0.0000 | 0.0664 | 0.0000 | 0.1660 | 0.0426 | 0.1618 | 0.0727 | 0.1826 | 0.1053 | 0.1826 | 0.1328 | 0.1369 | 0.1529 | 0.0788 | 0.4937 | 0.0000 | 0.0000 | 0.0146 | 0.0000 | 0.0292 | 0.0000 | 0.0437 | 0.0325 | 0.0787 | 0.0433 | 0.1108 | 0.0584 | 0.1224 | 0.0714 | 0.1866 | 0.0952 | 0.4140 | 0.6991 | 0.0392 | 0.0000 | 0.0392 | 0.0476 | 0.0686 | 0.0635 | 0.0490 | 0.0794 | 0.0784 | 0.1429 | 0.1961 | 0.1111 | 0.0980 | 0.1111 | 0.1275 | 0.1111 | 0.3039 | 0.3333 | 0.0051 | 0.0256 | 0.0718 | 0.0821 | 0.1026 | 0.1333 | 0.1385 | 0.1179 | 0.3231 | 3 | 3 | 4 | 5 | 5 | 7 | 7 | 7 | 9 | 0.0300 | 14.00 | 3.917 | 0.2952 | 35.4 | 257.772 | 2032.6 | 17052.4 | 0.3900 | 0.1941 | 0.1136 | 0.0290 | 0.2652 | 0.0773 | 0.2803 | 0.2174 | 0.1667 | 0.2560 | 0.0909 | 0.2029 | 0.0530 | 0.1353 | 0.0303 | 0.0628 | 0.0000 | 0.0145 | 0.0000 | 0.0048 | 0.0032 | 0.0000 | 0.0194 | 0.0079 | 0.0809 | 0.0159 | 0.1748 | 0.0714 | 0.2201 | 0.1720 | 0.2071 | 0.1746 | 0.1909 | 0.2302 | 0.0906 | 0.2169 | 0.0129 | 0.1111 | 0.0734 | 0.0760 | 0.1751 | 0.2047 | 0.3277 | 0.3392 | 0.2260 | 0.2222 | 0.1186 | 0.0877 | 0.0395 | 0.0292 | 0.0395 | 0.0409 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0433 | 0.1300 | 0.2202 | 0.2238 | 0.1805 | 0.1336 | 0.0542 | 0.0072 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1249 | 769 | | 4803 | 11247 | 502.2 | 83.00 | 67.05 | 122.38 | 382 | 431 | 463 | 488 | 508 | 528 | 552 | 579 | 608 | 0.0648 | 729 | 1.156 | 88.46 | 33.06 | 1 | 0.0477 | 229 | 0.0014 | 23.98 | 6.830 | 0.2358 | 259094.0 | 137000000 | 73800000000 | 40500000000000 | 0.4284 | 0.2133 | 0.0011 | 0.0000 | 0.0019 | 0.0000 | 0.0044 | 0.0000 | 0.0091 | 0.0002 | 0.0299 | 0.0136 | 0.0517 | 0.0206 | 0.0575 | 0.0124 | 0.0811 | 0.0183 | 0.7632 | 0.9350 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0002 | 0.0170 | 0.0136 | 0.0276 | 0.0206 | 0.0218 | 0.0124 | 0.0377 | 0.0183 | 0.8937 | 0.9350 | 0.0072 | 0.0000 | 0.0181 | 0.0000 | 0.0325 | 0.0000 | 0.0597 | 0.0000 | 0.0868 | 0.0000 | 0.1374 | 0.0000 | 0.1230 | 0.0000 | 0.1754 | 0.0000 | 0.3599 | 0.0000 | 0.0019 | 0.0016 | 0.0054 | 0.0140 | 0.0384 | 0.0594 | 0.0602 | 0.0889 | 0.7301 | 6 | 8 | 10 | 12 | 15 | 20 | 38 | 86 | 207 | 0.1665 | 6.51 | 3.350 | 0.6502 | 19470.7 | 8860000 | 4860000000 | 2970000000000 | 0.5816 | 0.0962 | 0.0324 | 0.0043 | 0.1477 | 0.0208 | 0.2216 | 0.0720 | 0.2090 | 0.1276 | 0.1658 | 0.1753 | 0.1189 | 0.1840 | 0.0613 | 0.1372 | 0.0216 | 0.1345 | 0.0216 | 0.1441 | 0.0007 | 0.0003 | 0.0010 | 0.0009 | 0.0034 | 0.0039 | 0.0172 | 0.0128 | 0.0540 | 0.0538 | 0.0890 | 0.0805 | 0.0639 | 0.0589 | 0.0907 | 0.0838 | 0.6801 | 0.7050 | 0.0000 | 0.0005 | 0.0013 | 0.0019 | 0.0030 | 0.0033 | 0.0166 | 0.0196 | 0.0675 | 0.0650 | 0.0968 | 0.1182 | 0.0739 | 0.0715 | 0.0994 | 0.1005 | 0.6416 | 0.6196 | 0.0004 | 0.0015 | 0.0034 | 0.0145 | 0.0574 | 0.1015 | 0.0624 | 0.0915 | 0.6673 | ||
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1218 | 913 | | 1758 | 2499 | 60.5 | 14.09 | 168.06 | 202.27 | 37 | 49 | 56 | 60 | 64 | 66 | 69 | 72 | 76 | 0.1709 | 427 | 1.246 | 80.75 | 28.65 | 1 | 0.1115 | 196 | 0.0648 | 0.70 | 3.033 | 0.7245 | 3855.7 | 255103 | 17300000 | 1200000000 | 0.4086 | 0.2272 | 0.0020 | 0.0000 | 0.0127 | 0.0000 | 0.0402 | 0.0057 | 0.0412 | 0.0076 | 0.0794 | 0.0264 | 0.1039 | 0.0415 | 0.1265 | 0.0447 | 0.1657 | 0.0730 | 0.4284 | 0.8011 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0035 | 0.0056 | 0.0064 | 0.0062 | 0.0275 | 0.0249 | 0.0346 | 0.0386 | 0.0388 | 0.0311 | 0.0473 | 0.0398 | 0.8397 | 0.8538 | 0.0101 | 0.3889 | 0.0455 | 0.1667 | 0.0758 | 0.3889 | 0.0934 | 0.0556 | 0.1641 | 0.0000 | 0.1919 | 0.0000 | 0.1490 | 0.0000 | 0.1086 | 0.0000 | 0.1616 | 0.0000 | 0.0000 | 0.0036 | 0.0073 | 0.0255 | 0.0473 | 0.0673 | 0.1092 | 0.1583 | 0.5814 | 4 | 6 | 7 | 11 | 74 | 155 | 243 | 343 | 479 | 0.0246 | 19.24 | 4.564 | 0.3199 | 69139.4 | 35300000 | 20400000000 | 12900000000000 | 0.3902 | 0.2388 | 0.0270 | 0.0023 | 0.0991 | 0.0070 | 0.2748 | 0.0651 | 0.1802 | 0.1256 | 0.1036 | 0.1419 | 0.0856 | 0.2186 | 0.0901 | 0.1256 | 0.0676 | 0.0814 | 0.0721 | 0.2326 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0025 | 0.0102 | 0.0076 | 0.0361 | 0.0352 | 0.0981 | 0.0730 | 0.0796 | 0.0554 | 0.0907 | 0.0671 | 0.6824 | 0.7592 | 0.0000 | 0.0013 | 0.0000 | 0.0039 | 0.0012 | 0.0066 | 0.0210 | 0.0197 | 0.0723 | 0.0748 | 0.1142 | 0.1391 | 0.1037 | 0.1063 | 0.1224 | 0.1299 | 0.5653 | 0.5184 | 0.0000 | 0.0031 | 0.0031 | 0.0084 | 0.0670 | 0.0974 | 0.0827 | 0.1068 | 0.6314 | ||
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 213 | 896 | | 3746 | 14440 | 324.0 | 67.68 | 163.52 | 174.35 | 235 | 267 | 288 | 305 | 322 | 340 | 359 | 382 | 414 | 0.0614 | 886 | 1.026 | 90.35 | 31.58 | 1 | 0.0670 | 251 | 0.0007 | 89.85 | 7.502 | 0.1378 | 109544.0 | 38500000 | 14000000000 | 5270000000000 | 0.4313 | 0.2081 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0008 | 0.0143 | 0.0014 | 0.0573 | 0.0161 | 0.1297 | 0.0417 | 0.1481 | 0.0296 | 0.1661 | 0.0735 | 0.4822 | 0.8369 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0052 | 0.0014 | 0.0223 | 0.0128 | 0.0419 | 0.0312 | 0.0461 | 0.0115 | 0.0652 | 0.0325 | 0.8187 | 0.9101 | 0.0015 | 0.0741 | 0.0092 | 0.0556 | 0.0382 | 0.0926 | 0.0947 | 0.1667 | 0.1740 | 0.1852 | 0.1969 | 0.1481 | 0.1191 | 0.0926 | 0.1481 | 0.1111 | 0.2183 | 0.0741 | 0.0000 | 0.0005 | 0.0054 | 0.0264 | 0.0696 | 0.1192 | 0.1154 | 0.1472 | 0.5162 | 13 | 17 | 27 | 55 | 99 | 150 | 212 | 304 | 427 | 0.0207 | 22.64 | 5.797 | 0.4177 | 57133.8 | 26400000 | 14400000000 | 8750000000000 | 0.5240 | 0.1275 | 0.0365 | 0.0012 | 0.1204 | 0.0053 | 0.1762 | 0.0439 | 0.2018 | 0.1082 | 0.1883 | 0.1766 | 0.1249 | 0.1778 | 0.0762 | 0.1466 | 0.0532 | 0.1487 | 0.0224 | 0.1917 | 0.0006 | 0.0004 | 0.0018 | 0.0006 | 0.0042 | 0.0024 | 0.0165 | 0.0138 | 0.0564 | 0.0447 | 0.0762 | 0.0656 | 0.0665 | 0.0531 | 0.0911 | 0.0798 | 0.6869 | 0.7397 | 0.0013 | 0.0013 | 0.0019 | 0.0043 | 0.0055 | 0.0080 | 0.0249 | 0.0268 | 0.0675 | 0.0771 | 0.0949 | 0.1009 | 0.0777 | 0.0746 | 0.0971 | 0.0949 | 0.6292 | 0.6123 | 0.0004 | 0.0022 | 0.0050 | 0.0187 | 0.0604 | 0.0872 | 0.0731 | 0.1006 | 0.6523 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 372 | 900 | | 5044 | 9324 | 570.5 | 98.09 | 110.30 | 193.81 | 423 | 504 | 548 | 574 | 591 | 608 | 625 | 644 | 675 | 0.0741 | 691 | 0.949 | 144.16 | 41.87 | 3 | 0.0765 | 386 | 0.0009 | 58.08 | 7.313 | 0.1858 | 335121.0 | 201000000 | 123000000000 | 76200000000000 | 0.4530 | 0.1918 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0002 | 0.0055 | 0.0012 | 0.0271 | 0.0139 | 0.0472 | 0.0212 | 0.0462 | 0.0133 | 0.0650 | 0.0234 | 0.8066 | 0.9268 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0018 | 0.0012 | 0.0148 | 0.0139 | 0.0237 | 0.0212 | 0.0189 | 0.0133 | 0.0283 | 0.0218 | 0.9121 | 0.9285 | 0.0051 | 1.0000 | 0.0204 | 0.0000 | 0.0382 | 0.0000 | 0.0789 | 0.0000 | 0.1399 | 0.0000 | 0.1527 | 0.0000 | 0.1425 | 0.0000 | 0.1552 | 0.0000 | 0.2672 | 0.0000 | 0.0006 | 0.0016 | 0.0039 | 0.0132 | 0.0319 | 0.0631 | 0.0673 | 0.0879 | 0.7304 | 13 | 15 | 17 | 20 | 24 | 37 | 65 | 143 | 347 | 0.2499 | 4.68 | 3.068 | 0.7533 | 49725.0 | 35000000 | 30000000000 | 29200000000000 | 0.6863 | 0.0611 | 0.0201 | 0.0070 | 0.0828 | 0.0120 | 0.2081 | 0.0468 | 0.1834 | 0.0807 | 0.1969 | 0.1723 | 0.1454 | 0.1912 | 0.0805 | 0.1524 | 0.0403 | 0.1404 | 0.0425 | 0.1972 | 0.0004 | 0.0022 | 0.0004 | 0.0022 | 0.0021 | 0.0065 | 0.0116 | 0.0151 | 0.0418 | 0.0391 | 0.0708 | 0.0613 | 0.0472 | 0.0459 | 0.0911 | 0.0911 | 0.7345 | 0.7368 | 0.0000 | 0.0006 | 0.0005 | 0.0006 | 0.0051 | 0.0011 | 0.0142 | 0.0146 | 0.0524 | 0.0611 | 0.0956 | 0.0952 | 0.0478 | 0.0538 | 0.0935 | 0.0947 | 0.6909 | 0.6784 | 0.0000 | 0.0000 | 0.0019 | 0.0116 | 0.0551 | 0.0811 | 0.0487 | 0.0982 | 0.7034 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1212 | 580 | | 1103 | 14618 | 561.7 | 138.16 | 35.88 | 63.16 | 370 | 419 | 468 | 517 | 560 | 608 | 658 | 706 | 751 | 0.0501 | 732 | 0.997 | 49.98 | 12.04 | 3 | 0.1024 | 113 | 0.0028 | 12.27 | 6.069 | 0.2960 | 334620.0 | 209000000 | 136000000000 | 91500000000000 | 0.3419 | 0.2943 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.0000 | 0.0170 | 0.0039 | 0.0679 | 0.0309 | 0.1434 | 0.0588 | 0.0830 | 0.0366 | 0.1264 | 0.0723 | 0.5566 | 0.7975 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0049 | 0.0019 | 0.0317 | 0.0272 | 0.0537 | 0.0497 | 0.0305 | 0.0244 | 0.0464 | 0.0384 | 0.8327 | 0.8585 | 0.0035 | 0.0667 | 0.0035 | 0.1000 | 0.0069 | 0.0667 | 0.0277 | 0.0667 | 0.0415 | 0.1667 | 0.1073 | 0.1667 | 0.0415 | 0.1000 | 0.0484 | 0.1333 | 0.7197 | 0.1333 | 0.0000 | 0.0000 | 0.0037 | 0.0147 | 0.0367 | 0.0606 | 0.0495 | 0.0495 | 0.7853 | 5 | 6 | 8 | 9 | 10 | 12 | 16 | 40 | 115 | 0.1429 | 1.10 | 2.444 | 0.5930 | 5276.5 | 1200000 | 317000000 | 92500000000 | 0.4895 | 0.1637 | 0.0684 | 0.0063 | 0.2928 | 0.0125 | 0.3403 | 0.0859 | 0.1521 | 0.2560 | 0.0665 | 0.3196 | 0.0418 | 0.1674 | 0.0209 | 0.0859 | 0.0114 | 0.0358 | 0.0057 | 0.0304 | 0.0003 | 0.0008 | 0.0006 | 0.0013 | 0.0015 | 0.0043 | 0.0150 | 0.0179 | 0.0479 | 0.0415 | 0.0814 | 0.0672 | 0.0568 | 0.0573 | 0.0912 | 0.0851 | 0.7054 | 0.7246 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0043 | 0.0011 | 0.0149 | 0.0164 | 0.0532 | 0.0611 | 0.0987 | 0.1019 | 0.0664 | 0.0710 | 0.1015 | 0.1111 | 0.6610 | 0.6366 | 0.0000 | 0.0003 | 0.0036 | 0.0098 | 0.0577 | 0.0925 | 0.0584 | 0.1013 | 0.6764 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1106 | 397 | | 3909 | 8740 | 289.1 | 95.66 | 91.54 | 172.00 | 154 | 205 | 243 | 269 | 293 | 316 | 338 | 365 | 406 | 0.0800 | 699 | 0.961 | 103.76 | 31.24 | 5 | 0.0686 | 268 | 0.0009 | 36.10 | 7.234 | 0.1915 | 92721.2 | 32200000 | 11900000000 | 4700000000000 | 0.3747 | 0.2534 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0027 | 0.0020 | 0.0142 | 0.0044 | 0.0650 | 0.0282 | 0.1301 | 0.0493 | 0.1055 | 0.0413 | 0.1301 | 0.0577 | 0.5497 | 0.8172 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0009 | 0.0021 | 0.0024 | 0.0202 | 0.0172 | 0.0401 | 0.0237 | 0.0262 | 0.0181 | 0.0391 | 0.0255 | 0.8713 | 0.9124 | 0.0010 | 0.0050 | 0.0048 | 0.0000 | 0.0096 | 0.0201 | 0.0231 | 0.0352 | 0.0723 | 0.0754 | 0.1070 | 0.1583 | 0.0762 | 0.0829 | 0.1022 | 0.1231 | 0.6037 | 0.5000 | 0.0000 | 0.0005 | 0.0015 | 0.0098 | 0.0403 | 0.0811 | 0.0546 | 0.0728 | 0.7394 | 6 | 7 | 9 | 11 | 15 | 29 | 59 | 122 | 279 | 0.1076 | 18.25 | 4.063 | 0.6042 | 37960.0 | 23800000 | 17700000000 | 14700000000000 | 0.5729 | 0.1131 | 0.0104 | 0.0020 | 0.0849 | 0.0088 | 0.1594 | 0.0344 | 0.1946 | 0.0698 | 0.2070 | 0.1740 | 0.1698 | 0.1878 | 0.0787 | 0.1593 | 0.0600 | 0.1524 | 0.0352 | 0.2114 | 0.0004 | 0.0004 | 0.0026 | 0.0015 | 0.0030 | 0.0037 | 0.0159 | 0.0089 | 0.0434 | 0.0426 | 0.0606 | 0.0600 | 0.0585 | 0.0474 | 0.0912 | 0.0803 | 0.7243 | 0.7553 | 0.0000 | 0.0006 | 0.0038 | 0.0012 | 0.0011 | 0.0036 | 0.0125 | 0.0119 | 0.0554 | 0.0641 | 0.0760 | 0.0766 | 0.0662 | 0.0719 | 0.0928 | 0.1021 | 0.6922 | 0.6681 | 0.0005 | 0.0024 | 0.0049 | 0.0093 | 0.0480 | 0.0720 | 0.0587 | 0.0896 | 0.7146 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 489 | 816 | | 9613 | 19666 | 390.1 | 60.27 | 175.40 | 251.54 | 316 | 341 | 358 | 372 | 386 | 400 | 417 | 439 | 471 | 0.0499 | 981 | 1.140 | 113.53 | 39.96 | 1 | 0.0287 | 276 | 0.0011 | 38.49 | 7.151 | 0.1882 | 155802.0 | 63700000 | 26600000000 | 11400000000000 | 0.4343 | 0.2166 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0063 | 0.0003 | 0.0283 | 0.0097 | 0.0643 | 0.0203 | 0.0756 | 0.0131 | 0.1055 | 0.0246 | 0.7186 | 0.9320 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0028 | 0.0001 | 0.0131 | 0.0084 | 0.0304 | 0.0170 | 0.0306 | 0.0084 | 0.0456 | 0.0152 | 0.8770 | 0.9508 | 0.0087 | 0.0000 | 0.0135 | 0.0000 | 0.0279 | 0.0000 | 0.0983 | 0.0000 | 0.1387 | 0.0000 | 0.1513 | 0.0000 | 0.1416 | 0.0000 | 0.1262 | 0.0000 | 0.2938 | 0.0000 | 0.0011 | 0.0035 | 0.0104 | 0.0298 | 0.0782 | 0.1108 | 0.1017 | 0.1210 | 0.5436 | 14 | 16 | 20 | 33 | 69 | 120 | 189 | 295 | 474 | 0.0394 | 31.15 | 5.368 | 0.5068 | 94034.5 | 84100000 | 103000000000 | 154000000000000 | 0.3897 | 0.2589 | 0.0213 | 0.0011 | 0.1385 | 0.0082 | 0.2420 | 0.0616 | 0.1776 | 0.1065 | 0.1672 | 0.1616 | 0.1236 | 0.1947 | 0.0759 | 0.1312 | 0.0374 | 0.1260 | 0.0167 | 0.2092 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0018 | 0.0009 | 0.0087 | 0.0075 | 0.0520 | 0.0374 | 0.0873 | 0.0660 | 0.0601 | 0.0490 | 0.0912 | 0.0703 | 0.6988 | 0.7683 | 0.0002 | 0.0002 | 0.0016 | 0.0006 | 0.0035 | 0.0034 | 0.0199 | 0.0226 | 0.0723 | 0.0866 | 0.1159 | 0.1289 | 0.0783 | 0.0860 | 0.1143 | 0.1210 | 0.5940 | 0.5507 | 0.0000 | 0.0008 | 0.0022 | 0.0144 | 0.0633 | 0.0998 | 0.0700 | 0.1025 | 0.6469 |