High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 560 | 270 | 5568 | 18268 | 433.5 | 92.93 | 137.20 | 136.94 | 324 | 352 | 376 | 397 | 422 | 446 | 477 | 510 | 564 | 0.0541 | 989 | 1.182 | 95.60 | 36.50 | 1 | 0.0449 | 250 | 0.0012 | 33.93 | 7.010 | 0.1946 | 196527.0 | 93100000 | 46100000000 | 23700000000000 | 0.4332 | 0.2136 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0020 | 0.0002 | 0.0140 | 0.0011 | 0.0717 | 0.0192 | 0.1259 | 0.0400 | 0.1320 | 0.0390 | 0.1664 | 0.0581 | 0.4877 | 0.8422 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0064 | 0.0000 | 0.0304 | 0.0128 | 0.0556 | 0.0229 | 0.0530 | 0.0152 | 0.0754 | 0.0265 | 0.7781 | 0.9225 | 0.0031 | 0.0070 | 0.0071 | 0.0245 | 0.0224 | 0.0280 | 0.0671 | 0.1294 | 0.1180 | 0.1993 | 0.1699 | 0.2133 | 0.1282 | 0.1084 | 0.1506 | 0.1434 | 0.3337 | 0.1469 | 0.0020 | 0.0016 | 0.0052 | 0.0290 | 0.0708 | 0.1225 | 0.0982 | 0.1301 | 0.5406 | 20 | 35 | 55 | 76 | 97 | 124 | 159 | 209 | 290 | 0.0125 | 11.31 | 5.396 | 0.4946 | 37572.9 | 16400000 | 9620000000 | 6730000000000 | 0.5560 | 0.1152 | 0.0139 | 0.0011 | 0.0448 | 0.0071 | 0.1227 | 0.0245 | 0.1370 | 0.0568 | 0.1652 | 0.1234 | 0.1675 | 0.1608 | 0.1217 | 0.1315 | 0.1118 | 0.1516 | 0.1154 | 0.3433 | 0.0013 | 0.0001 | 0.0016 | 0.0026 | 0.0052 | 0.0039 | 0.0169 | 0.0131 | 0.0498 | 0.0475 | 0.0829 | 0.0732 | 0.0663 | 0.0599 | 0.0861 | 0.0802 | 0.6900 | 0.7194 | 0.0015 | 0.0007 | 0.0029 | 0.0034 | 0.0061 | 0.0079 | 0.0209 | 0.0274 | 0.0672 | 0.0758 | 0.1087 | 0.1185 | 0.0846 | 0.0902 | 0.1045 | 0.1152 | 0.6036 | 0.5609 | 0.0021 | 0.0021 | 0.0044 | 0.0190 | 0.0539 | 0.0970 | 0.0768 | 0.0992 | 0.6453 | |
MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 817 | 307 | 12027 | 28545 | 384.6 | 103.18 | 211.70 | 323.15 | 261 | 292 | 319 | 344 | 373 | 404 | 437 | 474 | 525 | 0.0436 | 1244 | 0.752 | 109.04 | 32.80 | 1 | 0.0267 | 321 | 0.0007 | 50.15 | 7.537 | 0.1757 | 158542.0 | 69700000 | 32500000000 | 16000000000000 | 0.4289 | 0.2207 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0060 | 0.0004 | 0.0202 | 0.0027 | 0.1007 | 0.0201 | 0.1791 | 0.0552 | 0.1602 | 0.0555 | 0.1833 | 0.0782 | 0.3484 | 0.7879 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0011 | 0.0001 | 0.0064 | 0.0007 | 0.0379 | 0.0115 | 0.0683 | 0.0279 | 0.0628 | 0.0240 | 0.0862 | 0.0362 | 0.7370 | 0.8996 | 0.0014 | 0.0052 | 0.0061 | 0.0146 | 0.0112 | 0.0293 | 0.0404 | 0.0784 | 0.1156 | 0.1787 | 0.1603 | 0.1985 | 0.0932 | 0.0920 | 0.1564 | 0.1494 | 0.4153 | 0.2539 | 0.0018 | 0.0027 | 0.0054 | 0.0164 | 0.0567 | 0.1053 | 0.0810 | 0.1079 | 0.6227 | 8 | 10 | 13 | 17 | 35 | 112 | 226 | 396 | 663 | 0.1315 | 50.59 | 4.941 | 0.5343 | 149236.0 | 151000000 | 190000000000 | 278000000000000 | 0.5049 | 0.1716 | 0.0798 | 0.0036 | 0.2247 | 0.0328 | 0.2958 | 0.1757 | 0.1673 | 0.1637 | 0.1055 | 0.1861 | 0.0667 | 0.1779 | 0.0284 | 0.1106 | 0.0169 | 0.0810 | 0.0148 | 0.0684 | 0.0000 | 0.0002 | 0.0004 | 0.0005 | 0.0019 | 0.0005 | 0.0068 | 0.0058 | 0.0560 | 0.0442 | 0.0957 | 0.0808 | 0.0664 | 0.0597 | 0.1062 | 0.0944 | 0.6666 | 0.7139 | 0.0001 | 0.0001 | 0.0011 | 0.0012 | 0.0032 | 0.0032 | 0.0131 | 0.0145 | 0.0686 | 0.0791 | 0.1208 | 0.1326 | 0.0780 | 0.0825 | 0.1183 | 0.1317 | 0.5968 | 0.5551 | 0.0000 | 0.0006 | 0.0020 | 0.0124 | 0.0646 | 0.1037 | 0.0738 | 0.1162 | 0.6269 | |
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 213 | 896 | 3746 | 14440 | 324.0 | 67.68 | 163.52 | 174.35 | 235 | 267 | 288 | 305 | 322 | 340 | 359 | 382 | 414 | 0.0614 | 886 | 1.026 | 90.35 | 31.58 | 1 | 0.0670 | 251 | 0.0007 | 89.85 | 7.502 | 0.1378 | 109544.0 | 38500000 | 14000000000 | 5270000000000 | 0.4313 | 0.2081 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0008 | 0.0143 | 0.0014 | 0.0573 | 0.0161 | 0.1297 | 0.0417 | 0.1481 | 0.0296 | 0.1661 | 0.0735 | 0.4822 | 0.8369 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0052 | 0.0014 | 0.0223 | 0.0128 | 0.0419 | 0.0312 | 0.0461 | 0.0115 | 0.0652 | 0.0325 | 0.8187 | 0.9101 | 0.0015 | 0.0741 | 0.0092 | 0.0556 | 0.0382 | 0.0926 | 0.0947 | 0.1667 | 0.1740 | 0.1852 | 0.1969 | 0.1481 | 0.1191 | 0.0926 | 0.1481 | 0.1111 | 0.2183 | 0.0741 | 0.0000 | 0.0005 | 0.0054 | 0.0264 | 0.0696 | 0.1192 | 0.1154 | 0.1472 | 0.5162 | 13 | 17 | 27 | 55 | 99 | 150 | 212 | 304 | 427 | 0.0207 | 22.64 | 5.797 | 0.4177 | 57133.8 | 26400000 | 14400000000 | 8750000000000 | 0.5240 | 0.1275 | 0.0365 | 0.0012 | 0.1204 | 0.0053 | 0.1762 | 0.0439 | 0.2018 | 0.1082 | 0.1883 | 0.1766 | 0.1249 | 0.1778 | 0.0762 | 0.1466 | 0.0532 | 0.1487 | 0.0224 | 0.1917 | 0.0006 | 0.0004 | 0.0018 | 0.0006 | 0.0042 | 0.0024 | 0.0165 | 0.0138 | 0.0564 | 0.0447 | 0.0762 | 0.0656 | 0.0665 | 0.0531 | 0.0911 | 0.0798 | 0.6869 | 0.7397 | 0.0013 | 0.0013 | 0.0019 | 0.0043 | 0.0055 | 0.0080 | 0.0249 | 0.0268 | 0.0675 | 0.0771 | 0.0949 | 0.1009 | 0.0777 | 0.0746 | 0.0971 | 0.0949 | 0.6292 | 0.6123 | 0.0004 | 0.0022 | 0.0050 | 0.0187 | 0.0604 | 0.0872 | 0.0731 | 0.1006 | 0.6523 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 230 | 289 | 594 | 15656 | 100.5 | 15.06 | 36.01 | 54.50 | 85 | 89 | 91 | 94 | 96 | 100 | 105 | 110 | 120 | 0.0498 | 779 | 0.955 | 100.42 | 39.12 | 1 | 0.4916 | 292 | 0.0279 | 2.72 | 4.004 | 0.5272 | 10323.3 | 1090000 | 118000000 | 13200000000 | 0.4876 | 0.1693 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0017 | 0.0189 | 0.0156 | 0.0718 | 0.0469 | 0.1342 | 0.1267 | 0.0945 | 0.0729 | 0.1758 | 0.1181 | 0.4972 | 0.6181 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0034 | 0.0017 | 0.0136 | 0.0152 | 0.0560 | 0.0438 | 0.1070 | 0.1094 | 0.0594 | 0.0623 | 0.1171 | 0.0943 | 0.6435 | 0.6734 | 0.0167 | 0.0000 | 0.0000 | 0.0000 | 0.0500 | 0.0556 | 0.0667 | 0.0556 | 0.1333 | 0.2222 | 0.0833 | 0.3333 | 0.1500 | 0.0556 | 0.1500 | 0.1667 | 0.3500 | 0.1111 | 0.0080 | 0.0120 | 0.0279 | 0.0558 | 0.0996 | 0.0757 | 0.1235 | 0.1355 | 0.4622 | 7 | 9 | 11 | 13 | 15 | 19 | 26 | 43 | 94 | 0.1549 | 1.70 | 3.082 | 0.7448 | 4266.5 | 902121 | 242000000 | 74500000000 | 0.5337 | 0.1482 | 0.0320 | 0.0186 | 0.0756 | 0.0294 | 0.1496 | 0.0403 | 0.1676 | 0.0847 | 0.1746 | 0.1253 | 0.1652 | 0.1421 | 0.1216 | 0.1498 | 0.0889 | 0.1631 | 0.0249 | 0.2468 | 0.0064 | 0.0089 | 0.0093 | 0.0136 | 0.0091 | 0.0148 | 0.0209 | 0.0263 | 0.0483 | 0.0434 | 0.0699 | 0.0581 | 0.0665 | 0.0659 | 0.0883 | 0.0884 | 0.6813 | 0.6805 | 0.0016 | 0.0029 | 0.0045 | 0.0036 | 0.0103 | 0.0088 | 0.0251 | 0.0179 | 0.0527 | 0.0602 | 0.0730 | 0.0799 | 0.0685 | 0.0704 | 0.0894 | 0.0974 | 0.6749 | 0.6588 | 0.0038 | 0.0057 | 0.0085 | 0.0235 | 0.0569 | 0.0673 | 0.0687 | 0.0939 | 0.6715 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1125 | 641 | 11752 | 25342 | 232.5 | 61.19 | 170.59 | 255.96 | 162 | 186 | 201 | 215 | 228 | 242 | 257 | 278 | 310 | 0.0510 | 1293 | 1.092 | 30.46 | 9.43 | 3 | 0.0062 | 73 | 0.0008 | 52.10 | 7.510 | 0.1713 | 57786.2 | 15300000 | 4280000000 | 1270000000000 | 0.4266 | 0.2087 | 0.0003 | 0.0000 | 0.0011 | 0.0002 | 0.0038 | 0.0004 | 0.0137 | 0.0016 | 0.0570 | 0.0194 | 0.1221 | 0.0376 | 0.1242 | 0.0374 | 0.1725 | 0.0532 | 0.5053 | 0.8503 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0015 | 0.0000 | 0.0056 | 0.0005 | 0.0238 | 0.0113 | 0.0480 | 0.0188 | 0.0513 | 0.0158 | 0.0752 | 0.0235 | 0.7940 | 0.9300 | 0.0039 | 0.0023 | 0.0117 | 0.0081 | 0.0174 | 0.0151 | 0.0516 | 0.0755 | 0.0951 | 0.1231 | 0.1428 | 0.1649 | 0.0872 | 0.1115 | 0.1228 | 0.1161 | 0.4674 | 0.3833 | 0.0018 | 0.0029 | 0.0093 | 0.0250 | 0.0622 | 0.0988 | 0.0949 | 0.1131 | 0.5921 | 9 | 12 | 17 | 32 | 58 | 95 | 152 | 272 | 534 | 0.0689 | 34.29 | 5.267 | 0.5297 | 94612.1 | 77200000 | 75700000000 | 83200000000000 | 0.3585 | 0.3278 | 0.0395 | 0.0012 | 0.1512 | 0.0108 | 0.2256 | 0.0794 | 0.1461 | 0.1072 | 0.1502 | 0.1684 | 0.1169 | 0.1823 | 0.0707 | 0.1281 | 0.0608 | 0.1168 | 0.0390 | 0.2056 | 0.0006 | 0.0003 | 0.0021 | 0.0014 | 0.0038 | 0.0026 | 0.0153 | 0.0136 | 0.0581 | 0.0480 | 0.0869 | 0.0812 | 0.0666 | 0.0586 | 0.0861 | 0.0828 | 0.6805 | 0.7116 | 0.0002 | 0.0007 | 0.0019 | 0.0034 | 0.0056 | 0.0081 | 0.0251 | 0.0236 | 0.0640 | 0.0649 | 0.0941 | 0.0908 | 0.0674 | 0.0685 | 0.0855 | 0.0777 | 0.6563 | 0.6622 | 0.0007 | 0.0013 | 0.0062 | 0.0194 | 0.0623 | 0.0938 | 0.0645 | 0.0859 | 0.6660 | |||
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 692 | 185 | 19415 | 44441 | 368.7 | 56.02 | 244.04 | 276.54 | 299 | 324 | 341 | 357 | 370 | 384 | 398 | 414 | 438 | 0.0403 | 1792 | 0.714 | 124.33 | 24.70 | 1 | 0.0157 | 305 | 0.0014 | 22.18 | 6.923 | 0.2357 | 139081.0 | 53500000 | 21000000000 | 8390000000000 | 0.4311 | 0.2269 | 0.0001 | 0.0000 | 0.0008 | 0.0001 | 0.0028 | 0.0001 | 0.0066 | 0.0002 | 0.0259 | 0.0087 | 0.0530 | 0.0182 | 0.0576 | 0.0109 | 0.0865 | 0.0176 | 0.7667 | 0.9443 | 0.0001 | 0.0000 | 0.0004 | 0.0001 | 0.0011 | 0.0001 | 0.0033 | 0.0002 | 0.0141 | 0.0084 | 0.0282 | 0.0172 | 0.0273 | 0.0090 | 0.0375 | 0.0134 | 0.8880 | 0.9517 | 0.0119 | 0.0000 | 0.0209 | 0.0000 | 0.0346 | 0.0000 | 0.0930 | 0.0000 | 0.1169 | 0.0000 | 0.1574 | 0.0000 | 0.1199 | 0.0000 | 0.1306 | 0.0000 | 0.3148 | 0.0000 | 0.0012 | 0.0035 | 0.0100 | 0.0254 | 0.0509 | 0.0848 | 0.0988 | 0.1192 | 0.6061 | 17 | 22 | 30 | 54 | 118 | 220 | 341 | 473 | 647 | 0.0281 | 44.65 | 6.124 | 0.4266 | 136024.0 | 100000000 | 87800000000 | 88300000000000 | 0.4534 | 0.1804 | 0.0700 | 0.0020 | 0.2411 | 0.0134 | 0.3304 | 0.1499 | 0.1469 | 0.1951 | 0.0898 | 0.2149 | 0.0610 | 0.1886 | 0.0354 | 0.0976 | 0.0173 | 0.0724 | 0.0080 | 0.0662 | 0.0003 | 0.0002 | 0.0010 | 0.0004 | 0.0018 | 0.0013 | 0.0092 | 0.0076 | 0.0506 | 0.0416 | 0.1014 | 0.0881 | 0.0667 | 0.0543 | 0.0944 | 0.0803 | 0.6746 | 0.7262 | 0.0007 | 0.0004 | 0.0014 | 0.0017 | 0.0031 | 0.0043 | 0.0147 | 0.0194 | 0.0670 | 0.0789 | 0.1259 | 0.1392 | 0.0883 | 0.0943 | 0.1136 | 0.1275 | 0.5852 | 0.5343 | 0.0001 | 0.0007 | 0.0030 | 0.0105 | 0.0587 | 0.1131 | 0.0775 | 0.1049 | 0.6315 | |
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 484 | 784 | 7556 | 23389 | 282.7 | 59.70 | 166.78 | 196.60 | 210 | 231 | 247 | 262 | 276 | 293 | 311 | 334 | 366 | 0.0490 | 1145 | 1.213 | 102.16 | 38.05 | 1 | 0.0335 | 253 | 0.0006 | 75.57 | 7.614 | 0.1408 | 83467.9 | 25700000 | 8220000000 | 2730000000000 | 0.4316 | 0.2191 | 0.0002 | 0.0003 | 0.0006 | 0.0001 | 0.0020 | 0.0000 | 0.0170 | 0.0010 | 0.0677 | 0.0158 | 0.1511 | 0.0377 | 0.1521 | 0.0373 | 0.1708 | 0.0609 | 0.4384 | 0.8469 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0056 | 0.0004 | 0.0270 | 0.0106 | 0.0679 | 0.0232 | 0.0670 | 0.0160 | 0.0934 | 0.0265 | 0.7377 | 0.9233 | 0.0044 | 0.0233 | 0.0110 | 0.0233 | 0.0242 | 0.0631 | 0.0696 | 0.1728 | 0.1275 | 0.1960 | 0.1758 | 0.2060 | 0.1231 | 0.1063 | 0.1407 | 0.1296 | 0.3238 | 0.0797 | 0.0012 | 0.0035 | 0.0092 | 0.0372 | 0.0773 | 0.1330 | 0.1108 | 0.1304 | 0.4975 | 13 | 15 | 19 | 28 | 65 | 144 | 233 | 329 | 451 | 0.0382 | 38.04 | 5.638 | 0.4378 | 66466.3 | 34900000 | 21500000000 | 14900000000000 | 0.4729 | 0.1465 | 0.0850 | 0.0014 | 0.2309 | 0.0230 | 0.3225 | 0.1754 | 0.1274 | 0.1961 | 0.0928 | 0.2081 | 0.0531 | 0.1530 | 0.0330 | 0.0985 | 0.0279 | 0.0639 | 0.0274 | 0.0806 | 0.0000 | 0.0000 | 0.0005 | 0.0004 | 0.0009 | 0.0009 | 0.0084 | 0.0061 | 0.0473 | 0.0406 | 0.0840 | 0.0716 | 0.0667 | 0.0537 | 0.1009 | 0.0862 | 0.6912 | 0.7406 | 0.0001 | 0.0001 | 0.0013 | 0.0011 | 0.0031 | 0.0056 | 0.0161 | 0.0217 | 0.0677 | 0.0724 | 0.1058 | 0.1268 | 0.0903 | 0.0954 | 0.1290 | 0.1366 | 0.5867 | 0.5403 | 0.0000 | 0.0011 | 0.0013 | 0.0122 | 0.0536 | 0.0968 | 0.0807 | 0.1121 | 0.6423 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1173 | 230 | 893 | 1587 | 58.0 | 13.43 | 491.67 | 350.26 | 39 | 45 | 50 | 54 | 59 | 63 | 67 | 71 | 75 | 0.1878 | 298 | 1.216 | 22.85 | 8.25 | 1 | 0.0694 | 62 | 0.0063 | 5.77 | 5.275 | 0.3973 | 3548.7 | 226676 | 15000000 | 1020000000 | 0.4245 | 0.2042 | 0.0041 | 0.0000 | 0.0104 | 0.0000 | 0.0228 | 0.0012 | 0.0352 | 0.0119 | 0.1056 | 0.0380 | 0.1201 | 0.0403 | 0.1677 | 0.0712 | 0.1822 | 0.0830 | 0.3520 | 0.7544 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0058 | 0.0012 | 0.0159 | 0.0116 | 0.0418 | 0.0359 | 0.0390 | 0.0348 | 0.0592 | 0.0475 | 0.0649 | 0.0487 | 0.7706 | 0.8204 | 0.0095 | 0.0500 | 0.0143 | 0.1000 | 0.0190 | 0.0500 | 0.0476 | 0.2000 | 0.1381 | 0.3000 | 0.1095 | 0.1000 | 0.1810 | 0.0000 | 0.1905 | 0.2000 | 0.2905 | 0.0000 | 0.0043 | 0.0151 | 0.0151 | 0.0129 | 0.0430 | 0.0688 | 0.0860 | 0.1011 | 0.6538 | 107 | 162 | 233 | 315 | 418 | 517 | 636 | 803 | 998 | 0.0021 | 39.34 | 6.548 | 0.2363 | 364349.0 | 335000000 | 350000000000 | 398000000000000 | 0.5161 | 0.1411 | 0.0070 | 0.0000 | 0.0702 | 0.0035 | 0.1579 | 0.0228 | 0.2316 | 0.0683 | 0.2140 | 0.1278 | 0.1789 | 0.2277 | 0.0877 | 0.1611 | 0.0386 | 0.1664 | 0.0140 | 0.2224 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0061 | 0.0020 | 0.0255 | 0.0201 | 0.0522 | 0.0413 | 0.0765 | 0.0554 | 0.0667 | 0.0564 | 0.1129 | 0.0816 | 0.6590 | 0.7432 | 0.0019 | 0.0000 | 0.0000 | 0.0047 | 0.0111 | 0.0213 | 0.0390 | 0.0332 | 0.0686 | 0.0900 | 0.1317 | 0.1232 | 0.0891 | 0.0853 | 0.1132 | 0.1422 | 0.5455 | 0.5000 | 0.0000 | 0.0059 | 0.0089 | 0.0341 | 0.0548 | 0.0904 | 0.0919 | 0.1407 | 0.5733 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 346 | 701 | 14198 | 40387 | 106.4 | 32.10 | 146.17 | 188.92 | 72 | 82 | 90 | 96 | 103 | 110 | 118 | 129 | 144 | 0.0393 | 1589 | 0.755 | 201.22 | 48.27 | 2 | 0.0373 | 529 | 0.0026 | 18.07 | 6.363 | 0.2881 | 12345.6 | 1580000 | 229000000 | 39000000000 | 0.4708 | 0.1852 | 0.0007 | 0.0001 | 0.0041 | 0.0010 | 0.0119 | 0.0011 | 0.0333 | 0.0042 | 0.0850 | 0.0218 | 0.1598 | 0.0539 | 0.1708 | 0.0533 | 0.1970 | 0.0847 | 0.3372 | 0.7798 | 0.0002 | 0.0000 | 0.0011 | 0.0001 | 0.0015 | 0.0003 | 0.0096 | 0.0013 | 0.0331 | 0.0130 | 0.0687 | 0.0281 | 0.0706 | 0.0210 | 0.1052 | 0.0352 | 0.7101 | 0.9010 | 0.0061 | 0.0103 | 0.0105 | 0.0240 | 0.0243 | 0.0326 | 0.0723 | 0.1021 | 0.1348 | 0.1501 | 0.1713 | 0.1827 | 0.1203 | 0.1226 | 0.1413 | 0.1389 | 0.3190 | 0.2367 | 0.0017 | 0.0051 | 0.0119 | 0.0353 | 0.0818 | 0.1125 | 0.1127 | 0.1276 | 0.5114 | 12 | 14 | 17 | 21 | 38 | 97 | 181 | 289 | 433 | 0.0636 | 63.25 | 5.587 | 0.4594 | 57055.8 | 29900000 | 18300000000 | 12600000000000 | 0.5337 | 0.1336 | 0.0936 | 0.0033 | 0.2406 | 0.0356 | 0.2573 | 0.2023 | 0.1157 | 0.1813 | 0.1154 | 0.1677 | 0.0874 | 0.1514 | 0.0464 | 0.0816 | 0.0283 | 0.0770 | 0.0152 | 0.0996 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0022 | 0.0010 | 0.0084 | 0.0066 | 0.0488 | 0.0425 | 0.1001 | 0.0859 | 0.0667 | 0.0576 | 0.0957 | 0.0872 | 0.6770 | 0.7188 | 0.0006 | 0.0001 | 0.0009 | 0.0017 | 0.0039 | 0.0037 | 0.0107 | 0.0152 | 0.0648 | 0.0721 | 0.1272 | 0.1439 | 0.0905 | 0.0989 | 0.1204 | 0.1231 | 0.5809 | 0.5414 | 0.0005 | 0.0010 | 0.0023 | 0.0103 | 0.0565 | 0.1095 | 0.0807 | 0.1143 | 0.6250 | |
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 584 | 956 | 603 | 2463 | 406.2 | 49.35 | 106.45 | 171.74 | 341 | 360 | 374 | 391 | 405 | 421 | 434 | 449 | 475 | 0.1397 | 344 | 0.741 | 102.83 | 29.41 | 1 | 0.4809 | 290 | 0.0035 | 18.91 | 5.793 | 0.2498 | 167409.0 | 70000000 | 29700000000 | 12800000000000 | 0.3625 | 0.2807 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0037 | 0.0017 | 0.0608 | 0.0415 | 0.0958 | 0.0630 | 0.0608 | 0.0315 | 0.1105 | 0.0481 | 0.6648 | 0.8143 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0034 | 0.0017 | 0.0444 | 0.0415 | 0.0650 | 0.0630 | 0.0342 | 0.0315 | 0.0581 | 0.0481 | 0.7932 | 0.8143 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0952 | 0.0000 | 0.1190 | 0.0000 | 0.1905 | 0.0000 | 0.2381 | 0.0000 | 0.1429 | 0.0000 | 0.1190 | 0.0000 | 0.0952 | 0.0000 | 0.0000 | 0.0000 | 0.0101 | 0.0269 | 0.0842 | 0.1010 | 0.1010 | 0.1279 | 0.5488 | 8 | 10 | 11 | 13 | 15 | 30 | 107 | 188 | 310 | 0.1805 | 23.87 | 3.814 | 0.6487 | 40814.5 | 22400000 | 14400000000 | 10100000000000 | 0.5211 | 0.1245 | 0.0866 | 0.0122 | 0.0551 | 0.0528 | 0.1417 | 0.1098 | 0.2205 | 0.1138 | 0.1575 | 0.1301 | 0.1890 | 0.1707 | 0.0787 | 0.1220 | 0.0236 | 0.1260 | 0.0472 | 0.1626 | 0.0012 | 0.0000 | 0.0000 | 0.0047 | 0.0025 | 0.0070 | 0.0149 | 0.0117 | 0.0532 | 0.0493 | 0.0916 | 0.0880 | 0.0668 | 0.0563 | 0.0693 | 0.0599 | 0.7005 | 0.7230 | 0.0015 | 0.0017 | 0.0000 | 0.0033 | 0.0132 | 0.0132 | 0.0264 | 0.0281 | 0.0543 | 0.0677 | 0.1189 | 0.1254 | 0.0764 | 0.0858 | 0.0837 | 0.1073 | 0.6256 | 0.5677 | 0.0000 | 0.0013 | 0.0040 | 0.0148 | 0.0617 | 0.1074 | 0.0671 | 0.0832 | 0.6604 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 534 | 923 | 4850 | 8622 | 162.0 | 44.63 | 180.98 | 189.76 | 115 | 127 | 136 | 144 | 153 | 163 | 176 | 194 | 220 | 0.0923 | 796 | 1.107 | 100.01 | 36.69 | 1 | 0.0542 | 263 | 0.0016 | 35.56 | 6.803 | 0.2042 | 28220.0 | 5320000 | 1090000000 | 244000000000 | 0.4589 | 0.1995 | 0.0007 | 0.0000 | 0.0029 | 0.0005 | 0.0119 | 0.0016 | 0.0353 | 0.0018 | 0.0965 | 0.0224 | 0.1780 | 0.0576 | 0.1567 | 0.0576 | 0.1780 | 0.0908 | 0.3401 | 0.7676 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0024 | 0.0000 | 0.0113 | 0.0004 | 0.0464 | 0.0146 | 0.0848 | 0.0310 | 0.0754 | 0.0240 | 0.1095 | 0.0437 | 0.6690 | 0.8863 | 0.0021 | 0.0124 | 0.0095 | 0.0173 | 0.0148 | 0.0173 | 0.0674 | 0.0990 | 0.1349 | 0.1708 | 0.1802 | 0.1931 | 0.1117 | 0.0990 | 0.1454 | 0.1411 | 0.3340 | 0.2500 | 0.0025 | 0.0020 | 0.0129 | 0.0373 | 0.0821 | 0.1318 | 0.1035 | 0.1274 | 0.5005 | 14 | 24 | 41 | 71 | 110 | 159 | 230 | 325 | 469 | 0.0065 | 92.57 | 6.832 | 0.2972 | 68756.7 | 35000000 | 20900000000 | 13800000000000 | 0.4654 | 0.1787 | 0.0372 | 0.0015 | 0.1157 | 0.0126 | 0.2314 | 0.0576 | 0.2038 | 0.0919 | 0.1826 | 0.1859 | 0.1210 | 0.2273 | 0.0605 | 0.1485 | 0.0297 | 0.1348 | 0.0180 | 0.1399 | 0.0011 | 0.0005 | 0.0019 | 0.0018 | 0.0057 | 0.0016 | 0.0164 | 0.0127 | 0.0655 | 0.0540 | 0.0911 | 0.0881 | 0.0668 | 0.0623 | 0.0898 | 0.0865 | 0.6617 | 0.6924 | 0.0018 | 0.0000 | 0.0015 | 0.0081 | 0.0066 | 0.0098 | 0.0239 | 0.0242 | 0.0668 | 0.0752 | 0.1146 | 0.1134 | 0.0856 | 0.0935 | 0.1050 | 0.1143 | 0.5942 | 0.5616 | 0.0003 | 0.0028 | 0.0070 | 0.0215 | 0.0579 | 0.0958 | 0.0730 | 0.1078 | 0.6339 | |||
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1189 | 718 | 4088 | 19318 | 453.0 | 106.58 | 96.23 | 99.59 | 325 | 357 | 386 | 412 | 441 | 469 | 504 | 546 | 607 | 0.0500 | 965 | 1.115 | 111.23 | 32.65 | 1 | 0.0624 | 255 | 0.0007 | 67.51 | 7.409 | 0.1424 | 216555.0 | 109000000 | 57400000000 | 31500000000000 | 0.4176 | 0.2368 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0042 | 0.0003 | 0.0275 | 0.0040 | 0.0803 | 0.0242 | 0.1695 | 0.0594 | 0.1357 | 0.0548 | 0.1682 | 0.0698 | 0.4134 | 0.7875 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0100 | 0.0017 | 0.0344 | 0.0160 | 0.0821 | 0.0397 | 0.0581 | 0.0242 | 0.0865 | 0.0410 | 0.7264 | 0.8774 | 0.0012 | 0.0071 | 0.0084 | 0.0000 | 0.0096 | 0.0249 | 0.0646 | 0.1068 | 0.0969 | 0.1459 | 0.1352 | 0.1851 | 0.1172 | 0.1281 | 0.1148 | 0.1637 | 0.4522 | 0.2384 | 0.0016 | 0.0043 | 0.0070 | 0.0290 | 0.0774 | 0.1198 | 0.0956 | 0.1263 | 0.5390 | 8 | 11 | 16 | 33 | 63 | 99 | 134 | 174 | 230 | 0.0320 | 16.16 | 5.428 | 0.4394 | 19177.9 | 5220000 | 1780000000 | 719000000000 | 0.4849 | 0.1488 | 0.0329 | 0.0012 | 0.1667 | 0.0102 | 0.2528 | 0.0730 | 0.1924 | 0.1400 | 0.1450 | 0.1900 | 0.1015 | 0.2083 | 0.0551 | 0.1299 | 0.0343 | 0.1220 | 0.0193 | 0.1254 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0020 | 0.0012 | 0.0104 | 0.0077 | 0.0520 | 0.0427 | 0.0878 | 0.0780 | 0.0668 | 0.0541 | 0.0945 | 0.0813 | 0.6857 | 0.7349 | 0.0007 | 0.0007 | 0.0022 | 0.0028 | 0.0048 | 0.0102 | 0.0188 | 0.0254 | 0.0667 | 0.0816 | 0.1172 | 0.1331 | 0.0893 | 0.0932 | 0.1224 | 0.1264 | 0.5778 | 0.5265 | 0.0004 | 0.0004 | 0.0035 | 0.0151 | 0.0545 | 0.1053 | 0.0729 | 0.1062 | 0.6416 | |||
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 154 | 616 | 4931 | 13584 | 338.0 | 75.06 | 151.28 | 225.61 | 248 | 276 | 297 | 314 | 331 | 349 | 369 | 393 | 435 | 0.0692 | 940 | 1.116 | 97.91 | 41.00 | 1 | 0.0548 | 270 | 0.0006 | 91.32 | 7.643 | 0.1256 | 119887.0 | 44600000 | 17400000000 | 7130000000000 | 0.4061 | 0.2399 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0049 | 0.0002 | 0.0161 | 0.0013 | 0.0686 | 0.0206 | 0.1481 | 0.0465 | 0.1372 | 0.0463 | 0.1734 | 0.0725 | 0.4504 | 0.8126 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0017 | 0.0000 | 0.0077 | 0.0006 | 0.0334 | 0.0152 | 0.0762 | 0.0307 | 0.0589 | 0.0239 | 0.0885 | 0.0392 | 0.7329 | 0.8904 | 0.0049 | 0.0081 | 0.0173 | 0.0242 | 0.0260 | 0.0524 | 0.0803 | 0.0968 | 0.1224 | 0.1694 | 0.1706 | 0.1653 | 0.0952 | 0.1250 | 0.1323 | 0.1169 | 0.3511 | 0.2419 | 0.0026 | 0.0062 | 0.0132 | 0.0352 | 0.0835 | 0.1266 | 0.0976 | 0.1196 | 0.5156 | 12 | 15 | 17 | 21 | 30 | 64 | 148 | 279 | 478 | 0.0547 | 37.91 | 5.028 | 0.5176 | 73778.3 | 50900000 | 41900000000 | 39000000000000 | 0.5433 | 0.1208 | 0.1000 | 0.0025 | 0.2590 | 0.0318 | 0.2667 | 0.2116 | 0.1359 | 0.1906 | 0.0692 | 0.1957 | 0.0628 | 0.1449 | 0.0590 | 0.0870 | 0.0308 | 0.0654 | 0.0167 | 0.0705 | 0.0005 | 0.0000 | 0.0002 | 0.0004 | 0.0014 | 0.0018 | 0.0110 | 0.0108 | 0.0529 | 0.0494 | 0.0964 | 0.0818 | 0.0669 | 0.0566 | 0.1009 | 0.0895 | 0.6698 | 0.7097 | 0.0003 | 0.0003 | 0.0008 | 0.0009 | 0.0019 | 0.0021 | 0.0109 | 0.0162 | 0.0702 | 0.0748 | 0.1117 | 0.1200 | 0.0803 | 0.0967 | 0.1268 | 0.1281 | 0.5970 | 0.5609 | 0.0000 | 0.0025 | 0.0025 | 0.0099 | 0.0656 | 0.0992 | 0.0705 | 0.1173 | 0.6325 | |
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 957 | 935 | 646 | 1422 | 460.7 | 143.67 | 222.84 | 159.64 | 216 | 331 | 421 | 468 | 496 | 523 | 546 | 575 | 619 | 0.1871 | 266 | 0.763 | 79.76 | 18.68 | 1 | 0.3266 | 211 | 0.0022 | 28.41 | 6.205 | 0.2005 | 232878.0 | 124000000 | 68500000000 | 38700000000000 | 0.3597 | 0.2776 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0162 | 0.0000 | 0.1262 | 0.0594 | 0.1489 | 0.0792 | 0.1392 | 0.0554 | 0.1845 | 0.1030 | 0.3819 | 0.7030 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0531 | 0.0495 | 0.0510 | 0.0531 | 0.0367 | 0.0348 | 0.0633 | 0.0531 | 0.7959 | 0.8095 | 0.0000 | 0.0244 | 0.0000 | 0.0000 | 0.0110 | 0.0000 | 0.0166 | 0.0488 | 0.1105 | 0.1707 | 0.1050 | 0.1951 | 0.0718 | 0.0976 | 0.1768 | 0.1951 | 0.5083 | 0.2683 | 0.0000 | 0.0000 | 0.0000 | 0.0101 | 0.0503 | 0.0528 | 0.0503 | 0.0729 | 0.7638 | 56 | 82 | 113 | 138 | 181 | 233 | 281 | 347 | 458 | 0.0035 | 32.63 | 6.085 | 0.3061 | 75125.3 | 32400000 | 16200000000 | 8980000000000 | 0.5133 | 0.1452 | 0.0079 | 0.0019 | 0.0791 | 0.0228 | 0.1897 | 0.0342 | 0.2095 | 0.0684 | 0.1976 | 0.1369 | 0.1581 | 0.1882 | 0.0672 | 0.1673 | 0.0751 | 0.1616 | 0.0158 | 0.2186 | 0.0000 | 0.0000 | 0.0014 | 0.0023 | 0.0014 | 0.0034 | 0.0195 | 0.0103 | 0.0627 | 0.0479 | 0.1393 | 0.1130 | 0.0669 | 0.0628 | 0.1170 | 0.0982 | 0.5919 | 0.6621 | 0.0000 | 0.0029 | 0.0000 | 0.0000 | 0.0086 | 0.0114 | 0.0409 | 0.0657 | 0.1054 | 0.1457 | 0.1699 | 0.1514 | 0.1032 | 0.1257 | 0.1527 | 0.1429 | 0.4194 | 0.3543 | 0.0000 | 0.0017 | 0.0017 | 0.0305 | 0.0746 | 0.1542 | 0.0847 | 0.1339 | 0.5186 | |
MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 844 | 729 | 5195 | 6746 | 513.2 | 118.34 | 131.41 | 201.76 | 374 | 422 | 455 | 484 | 509 | 533 | 559 | 598 | 663 | 0.1269 | 856 | 1.179 | 136.50 | 52.00 | 4 | 0.0670 | 348 | 0.0006 | 81.67 | 7.590 | 0.1403 | 277409.0 | 157000000 | 93300000000 | 57800000000000 | 0.4641 | 0.1828 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0092 | 0.0002 | 0.0187 | 0.0015 | 0.0728 | 0.0317 | 0.1260 | 0.0589 | 0.1091 | 0.0502 | 0.1534 | 0.0757 | 0.5108 | 0.7819 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0037 | 0.0008 | 0.0387 | 0.0254 | 0.0701 | 0.0404 | 0.0576 | 0.0258 | 0.0831 | 0.0416 | 0.7456 | 0.8661 | 0.0059 | 0.0100 | 0.0118 | 0.0134 | 0.0178 | 0.0334 | 0.0675 | 0.1104 | 0.1349 | 0.1371 | 0.1527 | 0.1605 | 0.0982 | 0.1171 | 0.1396 | 0.1371 | 0.3716 | 0.2809 | 0.0012 | 0.0020 | 0.0083 | 0.0313 | 0.0944 | 0.1583 | 0.1035 | 0.1432 | 0.4578 | 7 | 9 | 11 | 15 | 30 | 63 | 128 | 229 | 416 | 0.1248 | 27.25 | 4.487 | 0.5729 | 57968.2 | 37400000 | 29800000000 | 27700000000000 | 0.6421 | 0.0717 | 0.0374 | 0.0045 | 0.1828 | 0.0269 | 0.3106 | 0.1256 | 0.1806 | 0.1469 | 0.1564 | 0.2096 | 0.0639 | 0.2096 | 0.0419 | 0.1188 | 0.0176 | 0.0953 | 0.0088 | 0.0628 | 0.0000 | 0.0004 | 0.0004 | 0.0024 | 0.0009 | 0.0028 | 0.0121 | 0.0108 | 0.0689 | 0.0667 | 0.1123 | 0.0895 | 0.0671 | 0.0667 | 0.0988 | 0.0927 | 0.6395 | 0.6681 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0028 | 0.0050 | 0.0213 | 0.0292 | 0.0786 | 0.0856 | 0.1296 | 0.1290 | 0.0836 | 0.0862 | 0.1072 | 0.1141 | 0.5758 | 0.5509 | 0.0000 | 0.0010 | 0.0035 | 0.0180 | 0.0721 | 0.1181 | 0.0756 | 0.1086 | 0.6031 | |
MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 700 | 12030 | 35050 | 359.5 | 76.99 | 172.29 | 212.34 | 266 | 289 | 311 | 331 | 350 | 372 | 398 | 428 | 469 | 0.0370 | 1298 | 1.080 | 120.07 | 37.70 | 1 | 0.0246 | 296 | 0.0007 | 42.37 | 7.437 | 0.1770 | 135186.0 | 53100000 | 21700000000 | 9200000000000 | 0.4257 | 0.2254 | 0.0007 | 0.0000 | 0.0024 | 0.0001 | 0.0047 | 0.0001 | 0.0166 | 0.0019 | 0.0578 | 0.0130 | 0.1117 | 0.0286 | 0.1278 | 0.0293 | 0.1729 | 0.0489 | 0.5054 | 0.8782 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0021 | 0.0000 | 0.0074 | 0.0004 | 0.0263 | 0.0079 | 0.0509 | 0.0166 | 0.0541 | 0.0114 | 0.0771 | 0.0203 | 0.7814 | 0.9434 | 0.0031 | 0.0144 | 0.0096 | 0.0431 | 0.0206 | 0.0431 | 0.0477 | 0.1150 | 0.0984 | 0.1889 | 0.1164 | 0.1725 | 0.1067 | 0.1376 | 0.1474 | 0.1212 | 0.4501 | 0.1643 | 0.0022 | 0.0027 | 0.0087 | 0.0265 | 0.0634 | 0.0961 | 0.0890 | 0.1053 | 0.6061 | 8 | 10 | 16 | 35 | 74 | 134 | 219 | 336 | 490 | 0.0515 | 30.59 | 5.525 | 0.4509 | 74768.6 | 43400000 | 30000000000 | 23500000000000 | 0.4088 | 0.2228 | 0.0812 | 0.0029 | 0.2274 | 0.0275 | 0.2491 | 0.1801 | 0.1201 | 0.1627 | 0.1228 | 0.1764 | 0.0750 | 0.1525 | 0.0533 | 0.1018 | 0.0392 | 0.0801 | 0.0320 | 0.1161 | 0.0001 | 0.0001 | 0.0002 | 0.0004 | 0.0010 | 0.0009 | 0.0095 | 0.0074 | 0.0610 | 0.0504 | 0.1018 | 0.0884 | 0.0671 | 0.0617 | 0.1083 | 0.0895 | 0.6509 | 0.7012 | 0.0002 | 0.0002 | 0.0005 | 0.0005 | 0.0022 | 0.0037 | 0.0162 | 0.0203 | 0.0769 | 0.0888 | 0.1277 | 0.1338 | 0.0832 | 0.0898 | 0.1251 | 0.1318 | 0.5682 | 0.5312 | 0.0003 | 0.0002 | 0.0015 | 0.0144 | 0.0678 | 0.1109 | 0.0804 | 0.1157 | 0.6087 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 688 | 324 | 13758 | 21485 | 122.6 | 40.36 | 202.58 | 231.30 | 76 | 90 | 98 | 107 | 117 | 128 | 141 | 156 | 178 | 0.0872 | 1874 | 0.692 | 86.83 | 17.09 | 4 | 0.0151 | 208 | 0.0009 | 37.58 | 7.369 | 0.2047 | 16661.6 | 2480000 | 400000000 | 69100000000 | 0.4692 | 0.2051 | 0.0024 | 0.0004 | 0.0062 | 0.0006 | 0.0139 | 0.0027 | 0.0405 | 0.0084 | 0.0991 | 0.0326 | 0.1598 | 0.0715 | 0.1633 | 0.0626 | 0.1771 | 0.0877 | 0.3378 | 0.7336 | 0.0011 | 0.0002 | 0.0029 | 0.0003 | 0.0047 | 0.0010 | 0.0145 | 0.0048 | 0.0370 | 0.0172 | 0.0555 | 0.0390 | 0.0585 | 0.0291 | 0.0729 | 0.0411 | 0.7528 | 0.8673 | 0.0020 | 0.0037 | 0.0072 | 0.0067 | 0.0133 | 0.0209 | 0.0372 | 0.0491 | 0.0847 | 0.1098 | 0.1175 | 0.1589 | 0.0893 | 0.1141 | 0.1233 | 0.1387 | 0.5255 | 0.3982 | 0.0010 | 0.0026 | 0.0073 | 0.0221 | 0.0578 | 0.0893 | 0.0766 | 0.1021 | 0.6413 | 15 | 20 | 31 | 57 | 109 | 182 | 259 | 358 | 545 | 0.0237 | 41.98 | 5.971 | 0.4277 | 94535.6 | 60700000 | 46900000000 | 41300000000000 | 0.5071 | 0.1526 | 0.0324 | 0.0022 | 0.1222 | 0.0156 | 0.1953 | 0.0725 | 0.1804 | 0.1085 | 0.1681 | 0.1619 | 0.1340 | 0.1825 | 0.0858 | 0.1314 | 0.0495 | 0.1367 | 0.0324 | 0.1888 | 0.0001 | 0.0005 | 0.0017 | 0.0015 | 0.0035 | 0.0027 | 0.0122 | 0.0106 | 0.0577 | 0.0494 | 0.0901 | 0.0778 | 0.0671 | 0.0552 | 0.0932 | 0.0791 | 0.6743 | 0.7233 | 0.0003 | 0.0010 | 0.0028 | 0.0034 | 0.0068 | 0.0100 | 0.0237 | 0.0359 | 0.0811 | 0.0934 | 0.1246 | 0.1344 | 0.0910 | 0.0879 | 0.1214 | 0.1091 | 0.5482 | 0.5250 | 0.0005 | 0.0019 | 0.0048 | 0.0175 | 0.0673 | 0.1061 | 0.0788 | 0.1115 | 0.6117 | |
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 599 | 374 | 6551 | 17041 | 267.6 | 66.19 | 105.49 | 114.89 | 194 | 211 | 226 | 241 | 255 | 271 | 293 | 319 | 363 | 0.0596 | 1016 | 1.053 | 98.33 | 35.17 | 1 | 0.0400 | 262 | 0.0008 | 56.30 | 7.438 | 0.1617 | 75974.1 | 22900000 | 7350000000 | 2490000000000 | 0.4000 | 0.2484 | 0.0008 | 0.0000 | 0.0034 | 0.0003 | 0.0047 | 0.0005 | 0.0238 | 0.0032 | 0.0663 | 0.0219 | 0.1305 | 0.0441 | 0.1370 | 0.0413 | 0.1859 | 0.0657 | 0.4477 | 0.8230 | 0.0004 | 0.0000 | 0.0022 | 0.0000 | 0.0022 | 0.0000 | 0.0124 | 0.0008 | 0.0271 | 0.0139 | 0.0574 | 0.0225 | 0.0594 | 0.0169 | 0.0936 | 0.0300 | 0.7454 | 0.9159 | 0.0048 | 0.0079 | 0.0072 | 0.0099 | 0.0183 | 0.0217 | 0.0462 | 0.0791 | 0.0916 | 0.1462 | 0.1371 | 0.1798 | 0.1139 | 0.1146 | 0.1394 | 0.1462 | 0.4414 | 0.2945 | 0.0018 | 0.0029 | 0.0058 | 0.0282 | 0.0762 | 0.1181 | 0.0986 | 0.1203 | 0.5482 | 12 | 15 | 20 | 33 | 58 | 96 | 143 | 192 | 256 | 0.0374 | 9.37 | 5.007 | 0.5330 | 24326.7 | 7980000 | 3300000000 | 1610000000000 | 0.5431 | 0.1194 | 0.0353 | 0.0003 | 0.2286 | 0.0100 | 0.3382 | 0.1134 | 0.1429 | 0.1621 | 0.1127 | 0.2268 | 0.0793 | 0.2001 | 0.0390 | 0.1222 | 0.0157 | 0.0806 | 0.0082 | 0.0845 | 0.0001 | 0.0000 | 0.0003 | 0.0005 | 0.0014 | 0.0004 | 0.0096 | 0.0081 | 0.0557 | 0.0459 | 0.1000 | 0.0861 | 0.0671 | 0.0552 | 0.0956 | 0.0849 | 0.6703 | 0.7189 | 0.0002 | 0.0006 | 0.0016 | 0.0026 | 0.0019 | 0.0060 | 0.0157 | 0.0227 | 0.0714 | 0.0843 | 0.1314 | 0.1389 | 0.0812 | 0.0897 | 0.1127 | 0.1180 | 0.5839 | 0.5372 | 0.0002 | 0.0008 | 0.0031 | 0.0103 | 0.0642 | 0.1150 | 0.0771 | 0.1071 | 0.6223 | |
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 260 | 906 | 6741 | 5810 | 457.5 | 85.03 | 189.24 | 346.87 | 354 | 397 | 434 | 457 | 471 | 484 | 497 | 515 | 542 | 0.1139 | 662 | 0.726 | 107.34 | 27.78 | 4 | 0.0481 | 324 | 0.0013 | 28.66 | 7.062 | 0.2336 | 216541.0 | 105000000 | 52100000000 | 26300000000000 | 0.4404 | 0.2127 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0038 | 0.0000 | 0.0072 | 0.0011 | 0.0244 | 0.0142 | 0.0415 | 0.0371 | 0.0385 | 0.0169 | 0.0651 | 0.0290 | 0.8182 | 0.9017 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0026 | 0.0000 | 0.0044 | 0.0005 | 0.0175 | 0.0138 | 0.0303 | 0.0338 | 0.0218 | 0.0135 | 0.0322 | 0.0208 | 0.8903 | 0.9176 | 0.0174 | 0.0000 | 0.0209 | 0.0000 | 0.0192 | 0.0000 | 0.0314 | 0.0000 | 0.0401 | 0.0000 | 0.0627 | 0.0000 | 0.0592 | 0.0000 | 0.0941 | 0.0000 | 0.6551 | 0.0000 | 0.0007 | 0.0045 | 0.0057 | 0.0172 | 0.0314 | 0.0528 | 0.0617 | 0.0889 | 0.7372 | 15 | 17 | 18 | 21 | 27 | 55 | 114 | 280 | 602 | 0.2435 | 18.42 | 3.549 | 0.6966 | 156109.0 | 197000000 | 310000000000 | 567000000000000 | 0.6374 | 0.0658 | 0.0763 | 0.0000 | 0.1968 | 0.0329 | 0.2129 | 0.1024 | 0.1566 | 0.1225 | 0.1406 | 0.1846 | 0.1245 | 0.1554 | 0.0482 | 0.1280 | 0.0361 | 0.1188 | 0.0080 | 0.1554 | 0.0013 | 0.0000 | 0.0019 | 0.0006 | 0.0039 | 0.0023 | 0.0142 | 0.0138 | 0.0685 | 0.0619 | 0.0931 | 0.0865 | 0.0672 | 0.0613 | 0.1002 | 0.0980 | 0.6496 | 0.6756 | 0.0008 | 0.0000 | 0.0031 | 0.0025 | 0.0046 | 0.0067 | 0.0208 | 0.0200 | 0.0701 | 0.0835 | 0.1017 | 0.0943 | 0.0770 | 0.0760 | 0.1063 | 0.1077 | 0.6156 | 0.6093 | 0.0000 | 0.0014 | 0.0043 | 0.0157 | 0.0686 | 0.1029 | 0.0657 | 0.1064 | 0.6350 | |
MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 854 | 405 | 7527 | 31665 | 388.4 | 72.66 | 93.45 | 141.02 | 301 | 326 | 347 | 364 | 382 | 400 | 421 | 447 | 487 | 0.0374 | 1185 | 1.088 | 108.58 | 28.32 | 1 | 0.0323 | 243 | 0.0008 | 48.68 | 7.360 | 0.1631 | 156148.0 | 64900000 | 27900000000 | 12400000000000 | 0.4021 | 0.2480 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0046 | 0.0001 | 0.0110 | 0.0014 | 0.0414 | 0.0136 | 0.1010 | 0.0353 | 0.0993 | 0.0248 | 0.1508 | 0.0388 | 0.5912 | 0.8859 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0001 | 0.0052 | 0.0005 | 0.0195 | 0.0099 | 0.0510 | 0.0234 | 0.0462 | 0.0107 | 0.0737 | 0.0159 | 0.8031 | 0.9394 | 0.0056 | 0.0138 | 0.0130 | 0.0826 | 0.0241 | 0.0872 | 0.0519 | 0.1193 | 0.1270 | 0.1560 | 0.1724 | 0.2294 | 0.1233 | 0.0917 | 0.1483 | 0.0734 | 0.3346 | 0.1468 | 0.0008 | 0.0025 | 0.0065 | 0.0239 | 0.0686 | 0.1113 | 0.0975 | 0.1231 | 0.5659 | 6 | 8 | 11 | 21 | 39 | 63 | 99 | 156 | 250 | 0.0635 | 9.53 | 4.513 | 0.5426 | 28619.4 | 17100000 | 15800000000 | 18600000000000 | 0.4450 | 0.1844 | 0.0328 | 0.0005 | 0.1395 | 0.0088 | 0.2204 | 0.0603 | 0.1624 | 0.1175 | 0.1549 | 0.1747 | 0.1262 | 0.2022 | 0.0836 | 0.1486 | 0.0471 | 0.1229 | 0.0331 | 0.1645 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0022 | 0.0027 | 0.0119 | 0.0124 | 0.0537 | 0.0399 | 0.0815 | 0.0673 | 0.0674 | 0.0542 | 0.0954 | 0.0807 | 0.6869 | 0.7423 | 0.0007 | 0.0007 | 0.0017 | 0.0008 | 0.0046 | 0.0050 | 0.0176 | 0.0205 | 0.0658 | 0.0826 | 0.1195 | 0.1283 | 0.0762 | 0.0818 | 0.1160 | 0.1209 | 0.5979 | 0.5594 | 0.0003 | 0.0015 | 0.0051 | 0.0174 | 0.0607 | 0.0986 | 0.0754 | 0.1077 | 0.6333 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 921 | 565 | 4515 | 12772 | 136.3 | 38.62 | 135.27 | 164.66 | 95 | 105 | 113 | 121 | 130 | 139 | 150 | 162 | 185 | 0.0755 | 964 | 1.187 | 118.21 | 44.41 | 1 | 0.0669 | 302 | 0.0020 | 26.20 | 6.545 | 0.2402 | 20065.9 | 3220000 | 568000000 | 111000000000 | 0.4520 | 0.1988 | 0.0008 | 0.0000 | 0.0063 | 0.0002 | 0.0079 | 0.0015 | 0.0359 | 0.0057 | 0.1031 | 0.0269 | 0.1647 | 0.0507 | 0.1686 | 0.0672 | 0.1675 | 0.0961 | 0.3452 | 0.7517 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0038 | 0.0000 | 0.0148 | 0.0023 | 0.0440 | 0.0169 | 0.0750 | 0.0289 | 0.0735 | 0.0321 | 0.1004 | 0.0456 | 0.6856 | 0.8742 | 0.0058 | 0.0106 | 0.0023 | 0.0079 | 0.0257 | 0.0475 | 0.0690 | 0.1055 | 0.1415 | 0.1583 | 0.1825 | 0.1900 | 0.1158 | 0.1161 | 0.1485 | 0.1451 | 0.3088 | 0.2190 | 0.0010 | 0.0041 | 0.0066 | 0.0259 | 0.0984 | 0.1324 | 0.1014 | 0.1460 | 0.4843 | 15 | 25 | 38 | 52 | 69 | 95 | 139 | 214 | 357 | 0.0059 | 46.41 | 6.387 | 0.3599 | 45409.4 | 23600000 | 15300000000 | 11300000000000 | 0.5555 | 0.1162 | 0.0282 | 0.0014 | 0.1229 | 0.0134 | 0.1832 | 0.0569 | 0.1691 | 0.0999 | 0.1660 | 0.1578 | 0.1644 | 0.1942 | 0.0854 | 0.1469 | 0.0517 | 0.1487 | 0.0290 | 0.1808 | 0.0009 | 0.0005 | 0.0011 | 0.0026 | 0.0036 | 0.0047 | 0.0189 | 0.0160 | 0.0560 | 0.0476 | 0.0910 | 0.0845 | 0.0674 | 0.0653 | 0.0964 | 0.0962 | 0.6647 | 0.6826 | 0.0003 | 0.0003 | 0.0015 | 0.0010 | 0.0050 | 0.0096 | 0.0207 | 0.0244 | 0.0645 | 0.0753 | 0.1112 | 0.1073 | 0.0721 | 0.0815 | 0.1076 | 0.1100 | 0.6171 | 0.5904 | 0.0013 | 0.0013 | 0.0066 | 0.0151 | 0.0602 | 0.0983 | 0.0748 | 0.0985 | 0.6440 | |||
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 125 | 887 | 914 | 10249 | 57.4 | 40.69 | 232.85 | 304.99 | 28 | 31 | 33 | 35 | 38 | 42 | 56 | 82 | 127 | 0.0631 | 647 | 1.229 | 27.66 | 9.43 | 1 | 0.0722 | 66 | 0.0076 | 22.99 | 5.445 | 0.3165 | 4951.9 | 588247 | 83100000 | 12800000000 | 0.3258 | 0.3035 | 0.0088 | 0.0152 | 0.0000 | 0.0127 | 0.0531 | 0.0482 | 0.1239 | 0.0736 | 0.3451 | 0.1624 | 0.2832 | 0.1574 | 0.1416 | 0.1650 | 0.0354 | 0.1421 | 0.0088 | 0.2234 | 0.0000 | 0.0103 | 0.0000 | 0.0086 | 0.0091 | 0.0325 | 0.0151 | 0.0462 | 0.0393 | 0.0856 | 0.0665 | 0.0805 | 0.0665 | 0.0702 | 0.0634 | 0.0771 | 0.7402 | 0.5890 | 0.0000 | 0.0053 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0046 | 0.0211 | 0.0826 | 0.0842 | 0.0872 | 0.0579 | 0.0459 | 0.0737 | 0.1101 | 0.0895 | 0.6697 | 0.6684 | 0.0000 | 0.0000 | 0.0037 | 0.0297 | 0.0409 | 0.0632 | 0.0743 | 0.0706 | 0.7175 | 22 | 26 | 32 | 50 | 83 | 141 | 256 | 424 | 686 | 0.0356 | 29.95 | 5.321 | 0.4926 | 147227.0 | 131000000 | 137000000000 | 161000000000000 | 0.6516 | 0.0660 | 0.0697 | 0.0026 | 0.1780 | 0.0222 | 0.2107 | 0.0941 | 0.1395 | 0.1359 | 0.1543 | 0.1737 | 0.1157 | 0.1966 | 0.0772 | 0.1261 | 0.0356 | 0.1261 | 0.0193 | 0.1228 | 0.0008 | 0.0002 | 0.0011 | 0.0012 | 0.0025 | 0.0051 | 0.0195 | 0.0177 | 0.0641 | 0.0572 | 0.0786 | 0.0824 | 0.0675 | 0.0545 | 0.0853 | 0.0863 | 0.6804 | 0.6953 | 0.0010 | 0.0015 | 0.0031 | 0.0035 | 0.0062 | 0.0073 | 0.0244 | 0.0289 | 0.0714 | 0.0763 | 0.0975 | 0.0960 | 0.0752 | 0.0867 | 0.0962 | 0.1044 | 0.6250 | 0.5954 | 0.0006 | 0.0012 | 0.0046 | 0.0178 | 0.0705 | 0.0911 | 0.0644 | 0.0929 | 0.6569 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 688 | 724 | 382 | 3170 | 111.2 | 49.61 | 43.27 | 125.08 | 45 | 55 | 71 | 91 | 111 | 133 | 151 | 163 | 177 | 0.1344 | 426 | 0.422 | 253.34 | 46.17 | 1 | 2.3037 | 880 | 0.0037 | 31.49 | 5.680 | 0.1888 | 14813.4 | 2190000 | 345000000 | 56300000000 | 0.2747 | 0.3491 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.2262 | 0.0345 | 0.3929 | 0.1379 | 0.2857 | 0.2184 | 0.0357 | 0.1494 | 0.0595 | 0.2184 | 0.0000 | 0.2356 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0072 | 0.0681 | 0.0578 | 0.0851 | 0.0866 | 0.0511 | 0.0433 | 0.0681 | 0.0650 | 0.7191 | 0.7401 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0194 | 0.0927 | 0.1553 | 0.1192 | 0.1165 | 0.0397 | 0.0971 | 0.1060 | 0.1165 | 0.6424 | 0.4854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0733 | 0.1257 | 0.0314 | 0.0733 | 0.6963 | 7 | 8 | 9 | 10 | 10 | 11 | 12 | 15 | 33 | 0.6117 | 5.34 | 1.436 | 0.8850 | 17511.8 | 11000000 | 7740000000 | 5940000000000 | 0.6927 | 0.0495 | 0.0357 | 0.0000 | 0.1429 | 0.0385 | 0.2857 | 0.0641 | 0.2143 | 0.1538 | 0.1786 | 0.2436 | 0.1429 | 0.1923 | 0.0000 | 0.1154 | 0.0000 | 0.1538 | 0.0000 | 0.0385 | 0.0032 | 0.0000 | 0.0064 | 0.0085 | 0.0064 | 0.0141 | 0.0129 | 0.0226 | 0.0386 | 0.0621 | 0.0611 | 0.0424 | 0.0675 | 0.0621 | 0.0868 | 0.1017 | 0.7170 | 0.6864 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0035 | 0.0000 | 0.0106 | 0.0181 | 0.0565 | 0.0471 | 0.0636 | 0.0870 | 0.0777 | 0.0725 | 0.0777 | 0.0725 | 0.7102 | 0.6993 | 0.0000 | 0.0000 | 0.0068 | 0.0102 | 0.0476 | 0.0612 | 0.0714 | 0.0884 | 0.7143 | |||
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1226 | 292 | 1447 | 9024 | 65.1 | 24.28 | 181.44 | 210.82 | 35 | 44 | 51 | 57 | 63 | 69 | 76 | 85 | 96 | 0.0659 | 595 | 0.521 | 83.49 | 16.03 | 5 | 0.1714 | 248 | 0.0021 | 31.10 | 6.361 | 0.2003 | 4823.6 | 400876 | 37000000 | 3760000000 | 0.3867 | 0.2406 | 0.0000 | 0.0000 | 0.0116 | 0.0000 | 0.0198 | 0.0028 | 0.0843 | 0.0170 | 0.1802 | 0.0405 | 0.2215 | 0.1008 | 0.1884 | 0.1329 | 0.1818 | 0.1951 | 0.1124 | 0.5108 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0016 | 0.0109 | 0.0095 | 0.0465 | 0.0247 | 0.0812 | 0.0366 | 0.0663 | 0.0461 | 0.1238 | 0.0700 | 0.6693 | 0.8115 | 0.0049 | 0.0255 | 0.0099 | 0.0204 | 0.0025 | 0.0510 | 0.0765 | 0.1071 | 0.1284 | 0.1837 | 0.1778 | 0.1735 | 0.1654 | 0.1173 | 0.1407 | 0.1378 | 0.2938 | 0.1837 | 0.0015 | 0.0029 | 0.0059 | 0.0322 | 0.1025 | 0.1259 | 0.1127 | 0.1347 | 0.4817 | 19 | 26 | 41 | 64 | 97 | 142 | 205 | 308 | 477 | 0.0338 | 9.96 | 5.000 | 0.5659 | 77361.5 | 47900000 | 36100000000 | 30600000000000 | 0.5191 | 0.1524 | 0.0220 | 0.0015 | 0.0828 | 0.0094 | 0.1118 | 0.0342 | 0.1577 | 0.0768 | 0.2126 | 0.1412 | 0.1427 | 0.1684 | 0.1228 | 0.1273 | 0.0918 | 0.1446 | 0.0559 | 0.2967 | 0.0006 | 0.0005 | 0.0025 | 0.0012 | 0.0034 | 0.0009 | 0.0104 | 0.0092 | 0.0533 | 0.0431 | 0.0855 | 0.0726 | 0.0676 | 0.0528 | 0.0917 | 0.0820 | 0.6851 | 0.7378 | 0.0008 | 0.0013 | 0.0027 | 0.0022 | 0.0059 | 0.0040 | 0.0164 | 0.0211 | 0.0632 | 0.0723 | 0.1096 | 0.1159 | 0.0780 | 0.0858 | 0.1166 | 0.1204 | 0.6069 | 0.5768 | 0.0003 | 0.0020 | 0.0043 | 0.0143 | 0.0627 | 0.0953 | 0.0720 | 0.1040 | 0.6450 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1251 | 214 | 356 | 5823 | 35.2 | 7.41 | 113.18 | 175.08 | 27 | 29 | 30 | 32 | 34 | 37 | 39 | 42 | 46 | 0.0792 | 461 | 0.420 | 101.19 | 15.26 | 1 | 0.8736 | 311 | 0.0113 | 6.98 | 4.700 | 0.3318 | 1292.1 | 49511.8 | 1970000 | 81800000 | 0.4112 | 0.2070 | 0.0000 | 0.0000 | 0.0044 | 0.0000 | 0.0439 | 0.0000 | 0.0877 | 0.0118 | 0.1711 | 0.0708 | 0.1798 | 0.0678 | 0.2719 | 0.1121 | 0.1491 | 0.1563 | 0.0921 | 0.5811 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0000 | 0.0261 | 0.0113 | 0.0554 | 0.0592 | 0.0782 | 0.0563 | 0.1401 | 0.0676 | 0.1759 | 0.0901 | 0.5049 | 0.7155 | 0.0127 | 0.0625 | 0.0000 | 0.1250 | 0.0759 | 0.0625 | 0.2532 | 0.2500 | 0.1646 | 0.1250 | 0.1772 | 0.1875 | 0.1139 | 0.1250 | 0.1013 | 0.0625 | 0.1013 | 0.0000 | 0.0000 | 0.0242 | 0.0424 | 0.0667 | 0.1030 | 0.1576 | 0.1455 | 0.1636 | 0.2970 | 16 | 20 | 25 | 33 | 45 | 68 | 103 | 161 | 264 | 0.0724 | 6.00 | 4.044 | 0.6522 | 43457.4 | 30200000 | 26300000000 | 25200000000000 | 0.6089 | 0.0954 | 0.0138 | 0.0044 | 0.0881 | 0.0044 | 0.1796 | 0.0413 | 0.1503 | 0.0739 | 0.1658 | 0.1706 | 0.1330 | 0.1715 | 0.1278 | 0.1407 | 0.0950 | 0.1416 | 0.0466 | 0.2515 | 0.0000 | 0.0009 | 0.0015 | 0.0004 | 0.0041 | 0.0017 | 0.0164 | 0.0133 | 0.0590 | 0.0506 | 0.0878 | 0.0665 | 0.0678 | 0.0545 | 0.0965 | 0.0982 | 0.6668 | 0.7139 | 0.0015 | 0.0000 | 0.0015 | 0.0017 | 0.0037 | 0.0050 | 0.0161 | 0.0209 | 0.0701 | 0.0771 | 0.1103 | 0.1131 | 0.0621 | 0.0737 | 0.1169 | 0.1307 | 0.6180 | 0.5779 | 0.0006 | 0.0031 | 0.0043 | 0.0210 | 0.0611 | 0.0945 | 0.0667 | 0.1050 | 0.6436 |