High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 945 | 791 | | 7136 | 8653 | 396.4 | 68.86 | 331.09 | 487.17 | 292 | 338 | 365 | 386 | 406 | 423 | 439 | 454 | 478 | 0.0953 | 825 | 1.046 | 109.66 | 38.48 | 6 | 0.0419 | 299 | 0.0024 | 9.08 | 6.362 | 0.3660 | 161888.0 | 67800000 | 29000000000 | 12700000000000 | 0.4181 | 0.2153 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0038 | 0.0000 | 0.0079 | 0.0011 | 0.0218 | 0.0106 | 0.0533 | 0.0271 | 0.0385 | 0.0132 | 0.0585 | 0.0186 | 0.8142 | 0.9294 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0011 | 0.0113 | 0.0105 | 0.0289 | 0.0260 | 0.0141 | 0.0119 | 0.0204 | 0.0173 | 0.9222 | 0.9333 | 0.0066 | 0.0000 | 0.0066 | 0.0000 | 0.0263 | 0.0000 | 0.0447 | 0.0000 | 0.1092 | 0.0000 | 0.1184 | 0.0000 | 0.1158 | 0.0000 | 0.1382 | 0.0000 | 0.4342 | 0.0000 | 0.0005 | 0.0015 | 0.0051 | 0.0101 | 0.0281 | 0.0398 | 0.0367 | 0.0529 | 0.8252 | 10 | 12 | 15 | 26 | 85 | 211 | 381 | 631 | 998 | 0.1055 | 26.80 | 5.014 | 0.5502 | 346927.0 | 541000000 | 1110000000000 | 2.77E+15 | 0.4761 | 0.1685 | 0.0161 | 0.0031 | 0.0966 | 0.0086 | 0.1804 | 0.0350 | 0.1739 | 0.0871 | 0.1643 | 0.1540 | 0.1433 | 0.1882 | 0.0934 | 0.1407 | 0.0805 | 0.1198 | 0.0515 | 0.2636 | 0.0003 | 0.0008 | 0.0006 | 0.0014 | 0.0025 | 0.0017 | 0.0063 | 0.0068 | 0.0348 | 0.0256 | 0.0659 | 0.0501 | 0.0446 | 0.0400 | 0.0681 | 0.0535 | 0.7768 | 0.8202 | 0.0000 | 0.0004 | 0.0004 | 0.0018 | 0.0039 | 0.0049 | 0.0102 | 0.0123 | 0.0481 | 0.0511 | 0.0777 | 0.0886 | 0.0560 | 0.0675 | 0.0765 | 0.0825 | 0.7272 | 0.6909 | 0.0000 | 0.0004 | 0.0036 | 0.0093 | 0.0411 | 0.0750 | 0.0496 | 0.0650 | 0.7562 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 259 | 595 | | 3281 | 8845 | 537.2 | 98.78 | 47.70 | 69.98 | 406 | 455 | 487 | 513 | 535 | 555 | 578 | 608 | 681 | 0.0684 | 605 | 1.005 | 109.84 | 37.48 | 2 | 0.0884 | 290 | 0.0012 | 24.77 | 6.942 | 0.2330 | 298323.0 | 171000000 | 101000000000 | 61500000000000 | 0.4559 | 0.1915 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0006 | 0.0295 | 0.0159 | 0.0565 | 0.0312 | 0.0510 | 0.0243 | 0.0674 | 0.0328 | 0.7880 | 0.8952 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0006 | 0.0159 | 0.0128 | 0.0297 | 0.0253 | 0.0244 | 0.0131 | 0.0304 | 0.0186 | 0.8956 | 0.9295 | 0.0066 | 0.0137 | 0.0088 | 0.0274 | 0.0243 | 0.0959 | 0.0133 | 0.0959 | 0.0575 | 0.2055 | 0.0973 | 0.1507 | 0.0619 | 0.1096 | 0.0841 | 0.1507 | 0.6460 | 0.1507 | 0.0012 | 0.0000 | 0.0025 | 0.0204 | 0.0532 | 0.0835 | 0.0884 | 0.1070 | 0.6438 | 8 | 9 | 11 | 12 | 14 | 19 | 46 | 78 | 131 | 0.2066 | 2.60 | 3.143 | 0.7617 | 7171.8 | 1810000 | 603000000 | 239000000000 | 0.5155 | 0.1378 | 0.0352 | 0.0029 | 0.0580 | 0.0155 | 0.0890 | 0.0638 | 0.1201 | 0.0629 | 0.1532 | 0.0977 | 0.1636 | 0.1460 | 0.1822 | 0.1199 | 0.1387 | 0.1586 | 0.0600 | 0.3327 | 0.0007 | 0.0007 | 0.0014 | 0.0020 | 0.0021 | 0.0029 | 0.0064 | 0.0085 | 0.0152 | 0.0186 | 0.0258 | 0.0232 | 0.0237 | 0.0235 | 0.0488 | 0.0405 | 0.8759 | 0.8803 | 0.0017 | 0.0015 | 0.0009 | 0.0039 | 0.0064 | 0.0064 | 0.0111 | 0.0148 | 0.0273 | 0.0261 | 0.0413 | 0.0542 | 0.0388 | 0.0473 | 0.0725 | 0.0719 | 0.8001 | 0.7740 | 0.0008 | 0.0008 | 0.0035 | 0.0096 | 0.0207 | 0.0261 | 0.0337 | 0.0560 | 0.8489 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1191 | 273 | | 5225 | 11025 | 340.7 | 62.23 | 307.66 | 490.68 | 248 | 283 | 309 | 330 | 349 | 367 | 381 | 396 | 416 | 0.0786 | 867 | 0.925 | 79.06 | 24.04 | 4 | 0.0404 | 211 | 0.0014 | 23.53 | 6.846 | 0.2524 | 119949.0 | 43400000 | 16100000000 | 6080000000000 | 0.4363 | 0.2015 | 0.0005 | 0.0000 | 0.0024 | 0.0000 | 0.0052 | 0.0004 | 0.0144 | 0.0012 | 0.0415 | 0.0155 | 0.0735 | 0.0306 | 0.0749 | 0.0196 | 0.1045 | 0.0333 | 0.6830 | 0.8994 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0014 | 0.0004 | 0.0046 | 0.0012 | 0.0191 | 0.0153 | 0.0353 | 0.0304 | 0.0290 | 0.0163 | 0.0376 | 0.0273 | 0.8719 | 0.9093 | 0.0076 | 0.0000 | 0.0291 | 1.0000 | 0.0443 | 0.0000 | 0.0581 | 0.0000 | 0.1407 | 0.0000 | 0.1361 | 0.0000 | 0.1300 | 0.0000 | 0.1529 | 0.0000 | 0.3012 | 0.0000 | 0.0007 | 0.0021 | 0.0070 | 0.0115 | 0.0369 | 0.0518 | 0.0539 | 0.0869 | 0.7493 | 8 | 10 | 12 | 16 | 25 | 61 | 277 | 673 | 1103 | 0.0635 | 24.60 | 4.331 | 0.4441 | 335399.0 | 461000000 | 722000000000 | 1.24E+15 | 0.5061 | 0.1164 | 0.0746 | 0.0000 | 0.2293 | 0.0218 | 0.2541 | 0.1592 | 0.1602 | 0.1687 | 0.1409 | 0.2082 | 0.0829 | 0.1891 | 0.0304 | 0.0898 | 0.0193 | 0.0939 | 0.0083 | 0.0694 | 0.0000 | 0.0000 | 0.0006 | 0.0006 | 0.0038 | 0.0011 | 0.0065 | 0.0047 | 0.0332 | 0.0356 | 0.0632 | 0.0601 | 0.0397 | 0.0361 | 0.0585 | 0.0593 | 0.7947 | 0.8025 | 0.0003 | 0.0003 | 0.0007 | 0.0003 | 0.0023 | 0.0017 | 0.0056 | 0.0055 | 0.0391 | 0.0464 | 0.0687 | 0.0695 | 0.0444 | 0.0488 | 0.0736 | 0.0768 | 0.7653 | 0.7506 | 0.0003 | 0.0012 | 0.0016 | 0.0068 | 0.0346 | 0.0626 | 0.0392 | 0.0688 | 0.7849 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1011 | 503 | | 8099 | 27715 | 207.4 | 49.29 | 90.32 | 133.45 | 151 | 164 | 175 | 187 | 199 | 212 | 228 | 248 | 276 | 0.0437 | 1212 | 1.109 | 152.01 | 45.19 | 2 | 0.0436 | 353 | 0.0011 | 36.08 | 7.089 | 0.1990 | 45423.4 | 10500000 | 2560000000 | 657000000000 | 0.4089 | 0.2364 | 0.0004 | 0.0000 | 0.0023 | 0.0001 | 0.0071 | 0.0004 | 0.0235 | 0.0021 | 0.0760 | 0.0188 | 0.1336 | 0.0422 | 0.1525 | 0.0391 | 0.1806 | 0.0611 | 0.4239 | 0.8362 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0001 | 0.0108 | 0.0006 | 0.0290 | 0.0107 | 0.0546 | 0.0216 | 0.0625 | 0.0137 | 0.0784 | 0.0235 | 0.7599 | 0.9297 | 0.0031 | 0.0101 | 0.0081 | 0.0067 | 0.0219 | 0.0236 | 0.0663 | 0.0809 | 0.1006 | 0.1720 | 0.1644 | 0.1585 | 0.1294 | 0.1282 | 0.1413 | 0.1619 | 0.3650 | 0.2580 | 0.0019 | 0.0022 | 0.0111 | 0.0259 | 0.0674 | 0.1078 | 0.1033 | 0.1236 | 0.5567 | 7 | 8 | 10 | 11 | 15 | 35 | 93 | 181 | 284 | 0.1964 | 12.37 | 4.050 | 0.6366 | 25966.7 | 10500000 | 5130000000 | 2920000000000 | 0.4760 | 0.1582 | 0.0839 | 0.0025 | 0.2737 | 0.0194 | 0.3606 | 0.1699 | 0.1380 | 0.2452 | 0.0745 | 0.2308 | 0.0467 | 0.1602 | 0.0182 | 0.0849 | 0.0044 | 0.0541 | 0.0000 | 0.0330 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0003 | 0.0003 | 0.0065 | 0.0072 | 0.0442 | 0.0379 | 0.0776 | 0.0649 | 0.0515 | 0.0468 | 0.0806 | 0.0673 | 0.7388 | 0.7756 | 0.0000 | 0.0001 | 0.0003 | 0.0006 | 0.0004 | 0.0007 | 0.0094 | 0.0113 | 0.0554 | 0.0601 | 0.1006 | 0.1144 | 0.0720 | 0.0756 | 0.1022 | 0.1029 | 0.6597 | 0.6343 | 0.0001 | 0.0000 | 0.0006 | 0.0064 | 0.0501 | 0.0888 | 0.0621 | 0.0936 | 0.6982 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1250 | 480 | | 6010 | 16284 | 271.9 | 68.74 | 353.07 | 523.57 | 175 | 224 | 245 | 264 | 279 | 293 | 309 | 328 | 354 | 0.0591 | 962 | 1.159 | 131.22 | 44.78 | 2 | 0.0542 | 326 | 0.0013 | 30.49 | 7.001 | 0.2258 | 78643.6 | 23800000 | 7440000000 | 2400000000000 | 0.4018 | 0.2328 | 0.0008 | 0.0000 | 0.0022 | 0.0004 | 0.0030 | 0.0013 | 0.0170 | 0.0019 | 0.0460 | 0.0171 | 0.0930 | 0.0344 | 0.1038 | 0.0340 | 0.1408 | 0.0511 | 0.5934 | 0.8598 | 0.0002 | 0.0000 | 0.0002 | 0.0002 | 0.0002 | 0.0005 | 0.0026 | 0.0011 | 0.0142 | 0.0116 | 0.0318 | 0.0207 | 0.0259 | 0.0136 | 0.0451 | 0.0223 | 0.8798 | 0.9300 | 0.0040 | 0.0119 | 0.0161 | 0.0357 | 0.0185 | 0.0238 | 0.0611 | 0.1111 | 0.0957 | 0.1905 | 0.1262 | 0.1905 | 0.1294 | 0.1349 | 0.1455 | 0.1706 | 0.4035 | 0.1310 | 0.0006 | 0.0009 | 0.0061 | 0.0148 | 0.0439 | 0.0742 | 0.0805 | 0.1147 | 0.6642 | 9 | 12 | 15 | 20 | 33 | 124 | 394 | 769 | 1226 | 0.0716 | 108.75 | 5.493 | 0.4880 | 398768.0 | 556000000 | 859000000000 | 1.42E+15 | 0.4180 | 0.2363 | 0.0593 | 0.0007 | 0.2062 | 0.0235 | 0.3032 | 0.1478 | 0.1442 | 0.1457 | 0.1078 | 0.1974 | 0.0876 | 0.1807 | 0.0499 | 0.1175 | 0.0337 | 0.0960 | 0.0081 | 0.0907 | 0.0000 | 0.0000 | 0.0004 | 0.0003 | 0.0016 | 0.0009 | 0.0066 | 0.0043 | 0.0421 | 0.0372 | 0.0706 | 0.0656 | 0.0492 | 0.0439 | 0.0706 | 0.0630 | 0.7590 | 0.7848 | 0.0002 | 0.0002 | 0.0019 | 0.0018 | 0.0028 | 0.0030 | 0.0118 | 0.0149 | 0.0476 | 0.0557 | 0.0800 | 0.0896 | 0.0607 | 0.0667 | 0.0891 | 0.0875 | 0.7059 | 0.6807 | 0.0004 | 0.0010 | 0.0028 | 0.0079 | 0.0436 | 0.0772 | 0.0515 | 0.0798 | 0.7360 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 376 | 670 | | 11475 | 30585 | 465.6 | 100.42 | 131.66 | 237.18 | 350 | 378 | 401 | 424 | 447 | 473 | 505 | 551 | 622 | 0.0430 | 1316 | 1.157 | 137.30 | 49.41 | 1 | 0.0297 | 341 | 0.0015 | 21.13 | 6.886 | 0.2666 | 226895.0 | 116000000 | 61700000000 | 34300000000000 | 0.4225 | 0.2239 | 0.0007 | 0.0000 | 0.0015 | 0.0002 | 0.0037 | 0.0005 | 0.0127 | 0.0019 | 0.0414 | 0.0147 | 0.0727 | 0.0296 | 0.0882 | 0.0265 | 0.1258 | 0.0409 | 0.6532 | 0.8857 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0014 | 0.0000 | 0.0059 | 0.0002 | 0.0182 | 0.0083 | 0.0338 | 0.0145 | 0.0420 | 0.0091 | 0.0610 | 0.0147 | 0.8365 | 0.9533 | 0.0028 | 0.0121 | 0.0080 | 0.0151 | 0.0099 | 0.0302 | 0.0274 | 0.0710 | 0.0690 | 0.1480 | 0.0922 | 0.1631 | 0.0813 | 0.1329 | 0.1068 | 0.1647 | 0.6026 | 0.2628 | 0.0008 | 0.0026 | 0.0051 | 0.0240 | 0.0431 | 0.0825 | 0.0785 | 0.0990 | 0.6644 | 5 | 6 | 8 | 9 | 12 | 26 | 86 | 218 | 471 | 0.1403 | 63.23 | 4.504 | 0.5576 | 73585.6 | 57500000 | 53700000000 | 56800000000000 | 0.4673 | 0.1625 | 0.0887 | 0.0045 | 0.2607 | 0.0499 | 0.2554 | 0.2123 | 0.1210 | 0.1544 | 0.1082 | 0.1653 | 0.0736 | 0.1423 | 0.0413 | 0.0927 | 0.0316 | 0.0855 | 0.0195 | 0.0931 | 0.0001 | 0.0000 | 0.0005 | 0.0003 | 0.0014 | 0.0003 | 0.0066 | 0.0066 | 0.0477 | 0.0419 | 0.0761 | 0.0690 | 0.0508 | 0.0460 | 0.0878 | 0.0763 | 0.7290 | 0.7595 | 0.0001 | 0.0001 | 0.0001 | 0.0010 | 0.0019 | 0.0016 | 0.0087 | 0.0121 | 0.0598 | 0.0631 | 0.0938 | 0.0985 | 0.0624 | 0.0744 | 0.1049 | 0.1107 | 0.6681 | 0.6384 | 0.0003 | 0.0003 | 0.0015 | 0.0081 | 0.0555 | 0.0813 | 0.0601 | 0.0971 | 0.6958 | ||
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1178 | 149 | | 2587 | 12832 | 62.1 | 10.66 | 74.22 | 169.03 | 47 | 54 | 57 | 60 | 63 | 65 | 68 | 71 | 75 | 0.0646 | 829 | 0.944 | 80.06 | 19.03 | 2 | 0.0723 | 187 | 0.0369 | 1.29 | 3.638 | 0.6360 | 3969.1 | 260301 | 17500000 | 1200000000 | 0.4305 | 0.2137 | 0.0020 | 0.0000 | 0.0020 | 0.0004 | 0.0055 | 0.0008 | 0.0201 | 0.0075 | 0.0472 | 0.0210 | 0.0693 | 0.0334 | 0.0844 | 0.0346 | 0.1920 | 0.0516 | 0.5774 | 0.8507 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0018 | 0.0004 | 0.0079 | 0.0059 | 0.0238 | 0.0192 | 0.0331 | 0.0298 | 0.0348 | 0.0271 | 0.0591 | 0.0365 | 0.8386 | 0.8811 | 0.0719 | 0.0968 | 0.1079 | 0.1290 | 0.0755 | 0.1935 | 0.1151 | 0.0968 | 0.1043 | 0.1613 | 0.1187 | 0.1613 | 0.1475 | 0.0968 | 0.0827 | 0.0645 | 0.1763 | 0.0000 | 0.0036 | 0.0107 | 0.0220 | 0.0377 | 0.0519 | 0.0732 | 0.1087 | 0.1741 | 0.5181 | 15 | 19 | 23 | 28 | 32 | 38 | 43 | 50 | 94 | 0.1646 | 3.32 | 2.652 | 0.8090 | 34078.2 | 30400000 | 31700000000 | 35800000000000 | 0.6942 | 0.0754 | 0.1033 | 0.0274 | 0.0813 | 0.0364 | 0.0769 | 0.0502 | 0.0769 | 0.0707 | 0.1319 | 0.1021 | 0.1275 | 0.1360 | 0.1319 | 0.1585 | 0.1275 | 0.1667 | 0.1429 | 0.2520 | 0.0237 | 0.0180 | 0.0188 | 0.0239 | 0.0094 | 0.0319 | 0.0066 | 0.0430 | 0.0248 | 0.0663 | 0.0370 | 0.0857 | 0.0304 | 0.1021 | 0.0679 | 0.1201 | 0.7815 | 0.5089 | 0.0044 | 0.0017 | 0.0044 | 0.0035 | 0.0074 | 0.0095 | 0.0118 | 0.0173 | 0.0376 | 0.0528 | 0.0516 | 0.0692 | 0.0553 | 0.0614 | 0.1061 | 0.0882 | 0.7214 | 0.6964 | 0.0006 | 0.0038 | 0.0038 | 0.0101 | 0.0258 | 0.0396 | 0.0491 | 0.0931 | 0.7742 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1140 | 503 | | 4025 | 13483 | 436.8 | 85.79 | 132.10 | 242.48 | 338 | 368 | 391 | 415 | 440 | 463 | 488 | 513 | 540 | 0.0518 | 698 | 1.105 | 49.03 | 18.38 | 2 | 0.0330 | 133 | 0.0012 | 33.18 | 6.972 | 0.2087 | 198109.0 | 92600000 | 44400000000 | 21800000000000 | 0.4526 | 0.1884 | 0.0007 | 0.0000 | 0.0014 | 0.0000 | 0.0035 | 0.0000 | 0.0139 | 0.0010 | 0.0522 | 0.0198 | 0.1099 | 0.0311 | 0.0967 | 0.0257 | 0.1398 | 0.0363 | 0.5819 | 0.8861 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0037 | 0.0005 | 0.0267 | 0.0189 | 0.0517 | 0.0288 | 0.0402 | 0.0186 | 0.0577 | 0.0283 | 0.8190 | 0.9049 | 0.0050 | 0.0000 | 0.0033 | 0.0606 | 0.0429 | 0.1515 | 0.0759 | 0.2121 | 0.1188 | 0.1212 | 0.1914 | 0.2424 | 0.1452 | 0.1515 | 0.1551 | 0.0303 | 0.2624 | 0.0303 | 0.0005 | 0.0024 | 0.0058 | 0.0169 | 0.0551 | 0.0851 | 0.0807 | 0.1054 | 0.6481 | 6 | 7 | 9 | 10 | 14 | 25 | 74 | 196 | 483 | 0.1545 | 27.57 | 4.157 | 0.6237 | 76242.5 | 60100000 | 54300000000 | 53300000000000 | 0.5764 | 0.1021 | 0.0301 | 0.0017 | 0.1284 | 0.0108 | 0.1997 | 0.0687 | 0.1458 | 0.1026 | 0.1838 | 0.1745 | 0.1331 | 0.1977 | 0.0666 | 0.1266 | 0.0602 | 0.1290 | 0.0523 | 0.1886 | 0.0003 | 0.0000 | 0.0005 | 0.0008 | 0.0025 | 0.0013 | 0.0066 | 0.0078 | 0.0442 | 0.0373 | 0.0700 | 0.0607 | 0.0437 | 0.0396 | 0.0626 | 0.0595 | 0.7696 | 0.7931 | 0.0000 | 0.0014 | 0.0013 | 0.0014 | 0.0027 | 0.0036 | 0.0166 | 0.0159 | 0.0525 | 0.0587 | 0.0807 | 0.0844 | 0.0558 | 0.0543 | 0.0751 | 0.0736 | 0.7153 | 0.7065 | 0.0003 | 0.0012 | 0.0033 | 0.0100 | 0.0504 | 0.0697 | 0.0573 | 0.0733 | 0.7346 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 420 | 742 | | 10935 | 36965 | 570.5 | 116.52 | 204.39 | 357.85 | 434 | 472 | 502 | 530 | 557 | 586 | 619 | 663 | 727 | 0.0445 | 1646 | 1.010 | 102.55 | 38.05 | 2 | 0.0258 | 282 | 0.0006 | 81.76 | 7.769 | 0.1488 | 339006.0 | 210000000 | 136000000000 | 92000000000000 | 0.4191 | 0.2288 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0035 | 0.0003 | 0.0113 | 0.0011 | 0.0543 | 0.0126 | 0.1116 | 0.0285 | 0.1155 | 0.0282 | 0.1447 | 0.0456 | 0.5584 | 0.8837 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0039 | 0.0003 | 0.0256 | 0.0086 | 0.0516 | 0.0165 | 0.0554 | 0.0121 | 0.0712 | 0.0199 | 0.7907 | 0.9426 | 0.0034 | 0.0123 | 0.0069 | 0.0369 | 0.0195 | 0.0541 | 0.0653 | 0.1253 | 0.1146 | 0.1695 | 0.1725 | 0.1892 | 0.1135 | 0.0983 | 0.1358 | 0.1007 | 0.3685 | 0.2138 | 0.0006 | 0.0044 | 0.0105 | 0.0277 | 0.0720 | 0.1148 | 0.0938 | 0.1191 | 0.5571 | 6 | 8 | 9 | 11 | 14 | 35 | 134 | 381 | 754 | 0.1781 | 65.60 | 4.468 | 0.5873 | 169829.0 | 188000000 | 243000000000 | 352000000000000 | 0.4094 | 0.2312 | 0.1194 | 0.0037 | 0.3132 | 0.0514 | 0.3248 | 0.2365 | 0.1171 | 0.2139 | 0.0620 | 0.1913 | 0.0302 | 0.1403 | 0.0225 | 0.0740 | 0.0078 | 0.0503 | 0.0031 | 0.0385 | 0.0000 | 0.0000 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0066 | 0.0033 | 0.0399 | 0.0364 | 0.0767 | 0.0693 | 0.0521 | 0.0427 | 0.0787 | 0.0708 | 0.7456 | 0.7764 | 0.0000 | 0.0000 | 0.0001 | 0.0003 | 0.0010 | 0.0015 | 0.0075 | 0.0101 | 0.0502 | 0.0538 | 0.0946 | 0.1037 | 0.0644 | 0.0702 | 0.0978 | 0.1071 | 0.6844 | 0.6533 | 0.0000 | 0.0002 | 0.0006 | 0.0068 | 0.0462 | 0.0827 | 0.0597 | 0.0911 | 0.7127 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 916 | 208 | | 6312 | 22401 | 516.6 | 108.92 | 194.68 | 249.60 | 387 | 432 | 460 | 485 | 506 | 529 | 554 | 590 | 659 | 0.0487 | 1092 | 1.116 | 137.30 | 45.69 | 1 | 0.0535 | 338 | 0.0007 | 69.42 | 7.543 | 0.1440 | 278766.0 | 157000000 | 92800000000 | 57400000000000 | 0.4428 | 0.2109 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0000 | 0.0104 | 0.0019 | 0.0576 | 0.0179 | 0.1165 | 0.0397 | 0.1247 | 0.0358 | 0.1680 | 0.0608 | 0.5208 | 0.8440 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0054 | 0.0008 | 0.0320 | 0.0120 | 0.0592 | 0.0239 | 0.0665 | 0.0194 | 0.0912 | 0.0340 | 0.7446 | 0.9099 | 0.0077 | 0.0096 | 0.0132 | 0.0096 | 0.0252 | 0.0382 | 0.0614 | 0.0669 | 0.1107 | 0.1369 | 0.1590 | 0.2452 | 0.0998 | 0.1051 | 0.1239 | 0.1624 | 0.3991 | 0.2261 | 0.0021 | 0.0045 | 0.0156 | 0.0403 | 0.0904 | 0.1255 | 0.1172 | 0.1321 | 0.4722 | 8 | 11 | 15 | 29 | 79 | 153 | 245 | 373 | 559 | 0.0687 | 42.39 | 5.505 | 0.4513 | 100197.0 | 70500000 | 59900000000 | 58200000000000 | 0.4609 | 0.1681 | 0.0552 | 0.0013 | 0.1678 | 0.0137 | 0.2533 | 0.1058 | 0.1683 | 0.1355 | 0.1438 | 0.1985 | 0.1037 | 0.1961 | 0.0500 | 0.1334 | 0.0302 | 0.1063 | 0.0276 | 0.1095 | 0.0003 | 0.0001 | 0.0002 | 0.0003 | 0.0016 | 0.0011 | 0.0067 | 0.0064 | 0.0528 | 0.0424 | 0.0871 | 0.0742 | 0.0642 | 0.0559 | 0.0943 | 0.0845 | 0.6926 | 0.7352 | 0.0001 | 0.0002 | 0.0007 | 0.0008 | 0.0026 | 0.0047 | 0.0182 | 0.0210 | 0.0633 | 0.0712 | 0.1119 | 0.1303 | 0.0840 | 0.0811 | 0.1128 | 0.1143 | 0.6064 | 0.5764 | 0.0003 | 0.0010 | 0.0028 | 0.0120 | 0.0577 | 0.0977 | 0.0730 | 0.1042 | 0.6513 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 842 | 577 | | 8312 | 37624 | 297.8 | 91.57 | 178.27 | 259.96 | 160 | 206 | 245 | 278 | 307 | 333 | 362 | 387 | 411 | 0.0319 | 1200 | 0.839 | 102.04 | 23.02 | 1 | 0.0298 | 248 | 0.0012 | 10.68 | 6.901 | 0.3043 | 97039.9 | 33700000 | 12200000000 | 4600000000000 | 0.3862 | 0.2351 | 0.0012 | 0.0000 | 0.0021 | 0.0005 | 0.0039 | 0.0017 | 0.0170 | 0.0054 | 0.0499 | 0.0240 | 0.0762 | 0.0398 | 0.0810 | 0.0408 | 0.1043 | 0.0580 | 0.6643 | 0.8299 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0003 | 0.0001 | 0.0033 | 0.0020 | 0.0152 | 0.0128 | 0.0244 | 0.0202 | 0.0207 | 0.0155 | 0.0268 | 0.0229 | 0.9088 | 0.9263 | 0.0015 | 0.0106 | 0.0030 | 0.0151 | 0.0049 | 0.0408 | 0.0118 | 0.0711 | 0.0323 | 0.0968 | 0.0433 | 0.1452 | 0.0429 | 0.0953 | 0.0771 | 0.1589 | 0.7831 | 0.3661 | 0.0009 | 0.0016 | 0.0029 | 0.0068 | 0.0201 | 0.0316 | 0.0289 | 0.0382 | 0.8689 | 8 | 10 | 12 | 16 | 37 | 86 | 182 | 353 | 594 | 0.1248 | 17.36 | 4.816 | 0.6022 | 99357.5 | 73300000 | 62400000000 | 58600000000000 | 0.4227 | 0.2238 | 0.0264 | 0.0016 | 0.1059 | 0.0050 | 0.1959 | 0.0402 | 0.1696 | 0.0969 | 0.1979 | 0.1765 | 0.1462 | 0.2004 | 0.0726 | 0.1356 | 0.0497 | 0.1265 | 0.0358 | 0.2174 | 0.0000 | 0.0002 | 0.0005 | 0.0004 | 0.0018 | 0.0011 | 0.0067 | 0.0062 | 0.0389 | 0.0323 | 0.0555 | 0.0517 | 0.0427 | 0.0407 | 0.0604 | 0.0544 | 0.7937 | 0.8129 | 0.0002 | 0.0007 | 0.0011 | 0.0010 | 0.0034 | 0.0033 | 0.0119 | 0.0117 | 0.0387 | 0.0431 | 0.0656 | 0.0654 | 0.0477 | 0.0528 | 0.0658 | 0.0696 | 0.7657 | 0.7523 | 0.0000 | 0.0006 | 0.0016 | 0.0095 | 0.0399 | 0.0611 | 0.0434 | 0.0640 | 0.7799 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 740 | 703 | | 8862 | 18824 | 530.1 | 80.43 | 114.15 | 251.56 | 421 | 467 | 496 | 517 | 535 | 553 | 573 | 598 | 631 | 0.0548 | 1032 | 0.545 | 114.22 | 22.67 | 5 | 0.0372 | 330 | 0.0009 | 38.41 | 7.314 | 0.2073 | 287452.0 | 159000000 | 89500000000 | 51200000000000 | 0.4491 | 0.2025 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0007 | 0.0001 | 0.0056 | 0.0007 | 0.0282 | 0.0139 | 0.0564 | 0.0200 | 0.0512 | 0.0144 | 0.0715 | 0.0211 | 0.7858 | 0.9298 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0016 | 0.0007 | 0.0179 | 0.0139 | 0.0306 | 0.0200 | 0.0252 | 0.0144 | 0.0335 | 0.0202 | 0.8913 | 0.9307 | 0.0075 | 1.0000 | 0.0188 | 0.0000 | 0.0225 | 0.0000 | 0.0476 | 0.0000 | 0.1164 | 0.0000 | 0.1640 | 0.0000 | 0.1014 | 0.0000 | 0.1502 | 0.0000 | 0.3717 | 0.0000 | 0.0006 | 0.0036 | 0.0074 | 0.0181 | 0.0434 | 0.0613 | 0.0734 | 0.0863 | 0.7059 | 9 | 10 | 12 | 13 | 15 | 20 | 38 | 121 | 352 | 0.1429 | 9.00 | 3.049 | 0.5952 | 76308.2 | 79500000 | 99600000000 | 139000000000000 | 0.5235 | 0.1294 | 0.0259 | 0.0023 | 0.0761 | 0.0164 | 0.2120 | 0.0561 | 0.1942 | 0.0865 | 0.2006 | 0.1645 | 0.1003 | 0.2050 | 0.1036 | 0.1458 | 0.0631 | 0.1341 | 0.0243 | 0.1894 | 0.0000 | 0.0004 | 0.0002 | 0.0004 | 0.0012 | 0.0011 | 0.0067 | 0.0072 | 0.0396 | 0.0383 | 0.0538 | 0.0475 | 0.0401 | 0.0385 | 0.0569 | 0.0591 | 0.8015 | 0.8073 | 0.0003 | 0.0000 | 0.0006 | 0.0006 | 0.0017 | 0.0021 | 0.0056 | 0.0079 | 0.0476 | 0.0539 | 0.0673 | 0.0667 | 0.0437 | 0.0521 | 0.0707 | 0.0758 | 0.7625 | 0.7409 | 0.0000 | 0.0005 | 0.0016 | 0.0065 | 0.0428 | 0.0586 | 0.0418 | 0.0664 | 0.7819 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 517 | 209 | | 10942 | 35449 | 447.3 | 110.82 | 142.08 | 205.96 | 312 | 350 | 381 | 410 | 439 | 469 | 501 | 538 | 598 | 0.0363 | 1286 | 0.903 | 94.01 | 21.02 | 3 | 0.0206 | 225 | 0.0006 | 67.31 | 7.714 | 0.1503 | 212393.0 | 107000000 | 56200000000 | 31100000000000 | 0.4346 | 0.2214 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0049 | 0.0003 | 0.0220 | 0.0020 | 0.0807 | 0.0222 | 0.1586 | 0.0494 | 0.1521 | 0.0568 | 0.1699 | 0.0831 | 0.4104 | 0.7861 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0011 | 0.0001 | 0.0069 | 0.0010 | 0.0331 | 0.0142 | 0.0664 | 0.0263 | 0.0584 | 0.0248 | 0.0766 | 0.0387 | 0.7570 | 0.8948 | 0.0022 | 0.0069 | 0.0081 | 0.0139 | 0.0103 | 0.0416 | 0.0550 | 0.1150 | 0.1279 | 0.1967 | 0.1699 | 0.1884 | 0.1225 | 0.1177 | 0.1516 | 0.1399 | 0.3524 | 0.1801 | 0.0008 | 0.0008 | 0.0065 | 0.0223 | 0.0687 | 0.1106 | 0.0929 | 0.1244 | 0.5730 | 7 | 10 | 12 | 15 | 24 | 71 | 163 | 276 | 443 | 0.1042 | 31.77 | 4.906 | 0.5483 | 62607.4 | 38100000 | 28100000000 | 23900000000000 | 0.4712 | 0.1726 | 0.0362 | 0.0022 | 0.1614 | 0.0112 | 0.2304 | 0.0744 | 0.1585 | 0.1487 | 0.1473 | 0.1922 | 0.1121 | 0.1786 | 0.0662 | 0.1198 | 0.0498 | 0.1135 | 0.0382 | 0.1594 | 0.0002 | 0.0001 | 0.0002 | 0.0002 | 0.0007 | 0.0005 | 0.0067 | 0.0061 | 0.0345 | 0.0311 | 0.0658 | 0.0530 | 0.0462 | 0.0389 | 0.0718 | 0.0600 | 0.7738 | 0.8102 | 0.0000 | 0.0005 | 0.0006 | 0.0007 | 0.0010 | 0.0021 | 0.0102 | 0.0107 | 0.0492 | 0.0560 | 0.0855 | 0.0946 | 0.0637 | 0.0738 | 0.0966 | 0.1019 | 0.6933 | 0.6595 | 0.0002 | 0.0003 | 0.0018 | 0.0074 | 0.0431 | 0.0740 | 0.0560 | 0.0876 | 0.7297 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 318 | 624 | | 6835 | 14487 | 545.4 | 80.10 | 171.75 | 314.77 | 430 | 485 | 516 | 537 | 554 | 568 | 585 | 605 | 635 | 0.0583 | 845 | 0.559 | 146.51 | 30.07 | 3 | 0.0660 | 451 | 0.0011 | 31.34 | 7.160 | 0.2167 | 303826.0 | 173000000 | 99800000000 | 58700000000000 | 0.4423 | 0.2040 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0046 | 0.0007 | 0.0219 | 0.0105 | 0.0376 | 0.0227 | 0.0393 | 0.0121 | 0.0589 | 0.0224 | 0.8363 | 0.9315 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0006 | 0.0138 | 0.0100 | 0.0230 | 0.0208 | 0.0226 | 0.0098 | 0.0272 | 0.0183 | 0.9111 | 0.9405 | 0.0093 | 0.0000 | 0.0163 | 0.0000 | 0.0280 | 0.0000 | 0.0676 | 0.0000 | 0.1189 | 0.0000 | 0.1352 | 0.0000 | 0.1119 | 0.0000 | 0.1119 | 0.0000 | 0.4009 | 0.0000 | 0.0008 | 0.0005 | 0.0050 | 0.0188 | 0.0379 | 0.0636 | 0.0767 | 0.0981 | 0.6986 | 11 | 13 | 15 | 19 | 25 | 47 | 102 | 252 | 575 | 0.1437 | 10.43 | 3.781 | 0.6289 | 128574.0 | 142000000 | 187000000000 | 273000000000000 | 0.3937 | 0.2546 | 0.0244 | 0.0022 | 0.0822 | 0.0126 | 0.1735 | 0.0445 | 0.1903 | 0.0867 | 0.2116 | 0.1890 | 0.1248 | 0.1883 | 0.0868 | 0.1401 | 0.0715 | 0.1371 | 0.0350 | 0.1994 | 0.0000 | 0.0005 | 0.0010 | 0.0007 | 0.0036 | 0.0030 | 0.0067 | 0.0079 | 0.0359 | 0.0345 | 0.0508 | 0.0483 | 0.0398 | 0.0391 | 0.0646 | 0.0606 | 0.7976 | 0.8055 | 0.0009 | 0.0007 | 0.0009 | 0.0010 | 0.0028 | 0.0020 | 0.0080 | 0.0081 | 0.0423 | 0.0430 | 0.0537 | 0.0696 | 0.0515 | 0.0545 | 0.0771 | 0.0794 | 0.7628 | 0.7418 | 0.0006 | 0.0014 | 0.0023 | 0.0093 | 0.0369 | 0.0544 | 0.0417 | 0.0668 | 0.7866 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 141 | 279 | | 6550 | 28560 | 325.2 | 76.94 | 118.00 | 205.38 | 229 | 259 | 281 | 299 | 318 | 339 | 361 | 391 | 431 | 0.0380 | 1086 | 1.019 | 88.10 | 26.68 | 3 | 0.0337 | 221 | 0.0007 | 63.80 | 7.487 | 0.1467 | 111704.0 | 40400000 | 15300000000 | 6070000000000 | 0.4422 | 0.2121 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0067 | 0.0012 | 0.0248 | 0.0030 | 0.0781 | 0.0206 | 0.1554 | 0.0495 | 0.1682 | 0.0513 | 0.1992 | 0.0834 | 0.3659 | 0.7909 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0003 | 0.0069 | 0.0006 | 0.0339 | 0.0127 | 0.0714 | 0.0286 | 0.0678 | 0.0219 | 0.0992 | 0.0413 | 0.7200 | 0.8945 | 0.0053 | 0.0096 | 0.0114 | 0.0288 | 0.0220 | 0.0745 | 0.0676 | 0.0962 | 0.1277 | 0.1923 | 0.1634 | 0.1635 | 0.1087 | 0.1130 | 0.1664 | 0.1394 | 0.3275 | 0.1827 | 0.0010 | 0.0043 | 0.0085 | 0.0299 | 0.0768 | 0.1404 | 0.1063 | 0.1358 | 0.4970 | 7 | 9 | 10 | 12 | 16 | 29 | 83 | 200 | 398 | 0.1579 | 24.15 | 4.168 | 0.5959 | 56105.0 | 38900000 | 32800000000 | 31500000000000 | 0.4719 | 0.1982 | 0.0778 | 0.0031 | 0.2645 | 0.0291 | 0.3497 | 0.1507 | 0.1482 | 0.1884 | 0.0819 | 0.2342 | 0.0426 | 0.1740 | 0.0180 | 0.0983 | 0.0098 | 0.0746 | 0.0074 | 0.0478 | 0.0000 | 0.0001 | 0.0004 | 0.0002 | 0.0004 | 0.0003 | 0.0067 | 0.0067 | 0.0467 | 0.0397 | 0.0880 | 0.0720 | 0.0536 | 0.0512 | 0.0899 | 0.0787 | 0.7143 | 0.7511 | 0.0001 | 0.0003 | 0.0004 | 0.0012 | 0.0016 | 0.0016 | 0.0092 | 0.0145 | 0.0557 | 0.0597 | 0.1096 | 0.1123 | 0.0663 | 0.0794 | 0.1060 | 0.1115 | 0.6510 | 0.6194 | 0.0000 | 0.0001 | 0.0019 | 0.0094 | 0.0525 | 0.0917 | 0.0654 | 0.0947 | 0.6842 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 817 | 307 | | 12027 | 28545 | 384.6 | 103.18 | 211.70 | 323.15 | 261 | 292 | 319 | 344 | 373 | 404 | 437 | 474 | 525 | 0.0436 | 1244 | 0.752 | 109.04 | 32.80 | 1 | 0.0267 | 321 | 0.0007 | 50.15 | 7.537 | 0.1757 | 158542.0 | 69700000 | 32500000000 | 16000000000000 | 0.4289 | 0.2207 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0060 | 0.0004 | 0.0202 | 0.0027 | 0.1007 | 0.0201 | 0.1791 | 0.0552 | 0.1602 | 0.0555 | 0.1833 | 0.0782 | 0.3484 | 0.7879 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0011 | 0.0001 | 0.0064 | 0.0007 | 0.0379 | 0.0115 | 0.0683 | 0.0279 | 0.0628 | 0.0240 | 0.0862 | 0.0362 | 0.7370 | 0.8996 | 0.0014 | 0.0052 | 0.0061 | 0.0146 | 0.0112 | 0.0293 | 0.0404 | 0.0784 | 0.1156 | 0.1787 | 0.1603 | 0.1985 | 0.0932 | 0.0920 | 0.1564 | 0.1494 | 0.4153 | 0.2539 | 0.0018 | 0.0027 | 0.0054 | 0.0164 | 0.0567 | 0.1053 | 0.0810 | 0.1079 | 0.6227 | 8 | 10 | 13 | 17 | 35 | 112 | 226 | 396 | 663 | 0.1315 | 50.59 | 4.941 | 0.5343 | 149236.0 | 151000000 | 190000000000 | 278000000000000 | 0.5049 | 0.1716 | 0.0798 | 0.0036 | 0.2247 | 0.0328 | 0.2958 | 0.1757 | 0.1673 | 0.1637 | 0.1055 | 0.1861 | 0.0667 | 0.1779 | 0.0284 | 0.1106 | 0.0169 | 0.0810 | 0.0148 | 0.0684 | 0.0000 | 0.0002 | 0.0004 | 0.0005 | 0.0019 | 0.0005 | 0.0068 | 0.0058 | 0.0560 | 0.0442 | 0.0957 | 0.0808 | 0.0664 | 0.0597 | 0.1062 | 0.0944 | 0.6666 | 0.7139 | 0.0001 | 0.0001 | 0.0011 | 0.0012 | 0.0032 | 0.0032 | 0.0131 | 0.0145 | 0.0686 | 0.0791 | 0.1208 | 0.1326 | 0.0780 | 0.0825 | 0.1183 | 0.1317 | 0.5968 | 0.5551 | 0.0000 | 0.0006 | 0.0020 | 0.0124 | 0.0646 | 0.1037 | 0.0738 | 0.1162 | 0.6269 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 324 | 279 | | 6286 | 20006 | 305.6 | 53.57 | 177.79 | 250.83 | 239 | 259 | 274 | 287 | 301 | 315 | 332 | 350 | 378 | 0.0542 | 1084 | 0.945 | 142.17 | 51.55 | 2 | 0.0668 | 420 | 0.0007 | 75.58 | 7.460 | 0.1491 | 96237.5 | 31200000 | 10400000000 | 3590000000000 | 0.4372 | 0.2228 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0141 | 0.0008 | 0.0512 | 0.0156 | 0.1137 | 0.0312 | 0.1268 | 0.0255 | 0.1662 | 0.0398 | 0.5258 | 0.8871 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0008 | 0.0262 | 0.0137 | 0.0626 | 0.0247 | 0.0593 | 0.0137 | 0.0930 | 0.0204 | 0.7543 | 0.9266 | 0.0036 | 0.0263 | 0.0238 | 0.0614 | 0.0321 | 0.0965 | 0.1021 | 0.2018 | 0.1437 | 0.1228 | 0.1698 | 0.2018 | 0.1235 | 0.0965 | 0.1508 | 0.0789 | 0.2506 | 0.1140 | 0.0017 | 0.0031 | 0.0099 | 0.0393 | 0.0866 | 0.1598 | 0.1071 | 0.1509 | 0.4417 | 14 | 17 | 19 | 22 | 29 | 66 | 192 | 371 | 581 | 0.0763 | 47.24 | 5.186 | 0.5166 | 94523.5 | 65400000 | 51600000000 | 44600000000000 | 0.4627 | 0.1598 | 0.0782 | 0.0011 | 0.2848 | 0.0210 | 0.3458 | 0.2017 | 0.1338 | 0.2254 | 0.0835 | 0.2125 | 0.0407 | 0.1528 | 0.0193 | 0.0780 | 0.0107 | 0.0511 | 0.0032 | 0.0565 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0008 | 0.0068 | 0.0056 | 0.0457 | 0.0401 | 0.0822 | 0.0776 | 0.0528 | 0.0434 | 0.0755 | 0.0672 | 0.7357 | 0.7653 | 0.0007 | 0.0004 | 0.0010 | 0.0004 | 0.0035 | 0.0019 | 0.0091 | 0.0124 | 0.0540 | 0.0569 | 0.0920 | 0.0927 | 0.0588 | 0.0732 | 0.0952 | 0.0987 | 0.6857 | 0.6635 | 0.0000 | 0.0000 | 0.0016 | 0.0107 | 0.0503 | 0.0851 | 0.0590 | 0.0788 | 0.7146 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 401 | 465 | | 5688 | 21468 | 395.0 | 83.99 | 124.18 | 239.02 | 290 | 326 | 352 | 373 | 392 | 410 | 430 | 457 | 504 | 0.0522 | 1120 | 1.175 | 146.10 | 54.92 | 1 | 0.0647 | 368 | 0.0007 | 85.77 | 7.563 | 0.1400 | 163082.0 | 70200000 | 31500000000 | 14700000000000 | 0.4503 | 0.2076 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0036 | 0.0000 | 0.0145 | 0.0009 | 0.0614 | 0.0220 | 0.1338 | 0.0403 | 0.1196 | 0.0438 | 0.1527 | 0.0645 | 0.5131 | 0.8284 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0036 | 0.0004 | 0.0302 | 0.0151 | 0.0598 | 0.0258 | 0.0550 | 0.0211 | 0.0858 | 0.0337 | 0.7648 | 0.9040 | 0.0011 | 0.0168 | 0.0078 | 0.0294 | 0.0343 | 0.0546 | 0.0676 | 0.1723 | 0.1495 | 0.1765 | 0.2137 | 0.2185 | 0.0952 | 0.0840 | 0.1384 | 0.0840 | 0.2924 | 0.1639 | 0.0018 | 0.0025 | 0.0094 | 0.0305 | 0.0864 | 0.1409 | 0.1097 | 0.1543 | 0.4644 | 7 | 8 | 9 | 11 | 13 | 19 | 59 | 166 | 460 | 0.2326 | 28.31 | 3.763 | 0.6555 | 72548.9 | 59000000 | 55500000000 | 57500000000000 | 0.4057 | 0.2332 | 0.0627 | 0.0034 | 0.2304 | 0.0282 | 0.2413 | 0.1477 | 0.1242 | 0.1167 | 0.1363 | 0.1635 | 0.0893 | 0.1860 | 0.0555 | 0.1037 | 0.0483 | 0.1020 | 0.0121 | 0.1488 | 0.0000 | 0.0002 | 0.0002 | 0.0000 | 0.0007 | 0.0015 | 0.0069 | 0.0057 | 0.0502 | 0.0393 | 0.0700 | 0.0667 | 0.0470 | 0.0434 | 0.0722 | 0.0667 | 0.7528 | 0.7766 | 0.0000 | 0.0002 | 0.0007 | 0.0007 | 0.0015 | 0.0021 | 0.0071 | 0.0088 | 0.0563 | 0.0601 | 0.0801 | 0.0852 | 0.0541 | 0.0560 | 0.0781 | 0.0805 | 0.7221 | 0.7063 | 0.0000 | 0.0000 | 0.0024 | 0.0088 | 0.0529 | 0.0768 | 0.0489 | 0.0729 | 0.7373 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 312 | 733 | | 7233 | 20217 | 523.9 | 88.32 | 192.73 | 354.08 | 412 | 444 | 470 | 496 | 519 | 544 | 571 | 604 | 641 | 0.0504 | 1018 | 1.154 | 114.98 | 42.58 | 1 | 0.0408 | 295 | 0.0018 | 19.88 | 6.575 | 0.2459 | 282245.0 | 156000000 | 88600000000 | 51500000000000 | 0.4172 | 0.2311 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0003 | 0.0114 | 0.0004 | 0.0461 | 0.0113 | 0.0920 | 0.0228 | 0.1143 | 0.0150 | 0.1514 | 0.0291 | 0.5824 | 0.9210 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0046 | 0.0001 | 0.0219 | 0.0096 | 0.0442 | 0.0195 | 0.0517 | 0.0096 | 0.0720 | 0.0186 | 0.8052 | 0.9427 | 0.0032 | 0.0494 | 0.0085 | 0.0247 | 0.0481 | 0.0617 | 0.1068 | 0.2099 | 0.1474 | 0.1481 | 0.1699 | 0.1728 | 0.1453 | 0.1605 | 0.1271 | 0.1111 | 0.2436 | 0.0617 | 0.0014 | 0.0026 | 0.0072 | 0.0203 | 0.0629 | 0.1090 | 0.0973 | 0.1296 | 0.5697 | 10 | 12 | 14 | 16 | 19 | 32 | 110 | 339 | 644 | 0.1456 | 63.21 | 4.433 | 0.6015 | 162507.0 | 200000000 | 303000000000 | 525000000000000 | 0.5064 | 0.1533 | 0.1318 | 0.0049 | 0.3100 | 0.0323 | 0.3324 | 0.2391 | 0.1234 | 0.2742 | 0.0561 | 0.2167 | 0.0351 | 0.1220 | 0.0042 | 0.0617 | 0.0056 | 0.0358 | 0.0014 | 0.0133 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0005 | 0.0003 | 0.0070 | 0.0065 | 0.0491 | 0.0410 | 0.0772 | 0.0740 | 0.0498 | 0.0478 | 0.0813 | 0.0702 | 0.7351 | 0.7600 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0004 | 0.0017 | 0.0119 | 0.0114 | 0.0544 | 0.0623 | 0.0908 | 0.0925 | 0.0634 | 0.0717 | 0.0934 | 0.1071 | 0.6854 | 0.6531 | 0.0000 | 0.0002 | 0.0008 | 0.0084 | 0.0511 | 0.0851 | 0.0532 | 0.0876 | 0.7136 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 826 | 707 | | 7372 | 21148 | 252.5 | 53.79 | 169.89 | 208.84 | 187 | 203 | 217 | 232 | 247 | 263 | 279 | 299 | 324 | 0.0440 | 931 | 0.980 | 86.83 | 30.02 | 1 | 0.0311 | 229 | 0.0008 | 53.24 | 7.330 | 0.1651 | 66652.7 | 18400000 | 5290000000 | 1590000000000 | 0.4618 | 0.1983 | 0.0000 | 0.0000 | 0.0015 | 0.0001 | 0.0048 | 0.0000 | 0.0231 | 0.0016 | 0.0808 | 0.0131 | 0.1549 | 0.0265 | 0.1579 | 0.0260 | 0.1862 | 0.0450 | 0.3908 | 0.8876 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0000 | 0.0101 | 0.0005 | 0.0353 | 0.0083 | 0.0679 | 0.0166 | 0.0713 | 0.0101 | 0.0901 | 0.0194 | 0.7234 | 0.9451 | 0.0023 | 0.0073 | 0.0083 | 0.0366 | 0.0264 | 0.0623 | 0.0746 | 0.1282 | 0.1432 | 0.1758 | 0.1907 | 0.1319 | 0.1311 | 0.1575 | 0.1409 | 0.0989 | 0.2826 | 0.2015 | 0.0003 | 0.0044 | 0.0075 | 0.0232 | 0.0786 | 0.1193 | 0.0987 | 0.1425 | 0.5255 | 10 | 12 | 15 | 27 | 67 | 141 | 237 | 331 | 459 | 0.0738 | 28.37 | 5.373 | 0.4963 | 72475.9 | 42400000 | 31000000000 | 26900000000000 | 0.4734 | 0.1923 | 0.0494 | 0.0029 | 0.2224 | 0.0070 | 0.3468 | 0.1140 | 0.1622 | 0.2051 | 0.0962 | 0.2533 | 0.0622 | 0.2019 | 0.0327 | 0.0889 | 0.0186 | 0.0625 | 0.0096 | 0.0644 | 0.0001 | 0.0001 | 0.0000 | 0.0000 | 0.0013 | 0.0007 | 0.0070 | 0.0057 | 0.0424 | 0.0396 | 0.0866 | 0.0755 | 0.0557 | 0.0466 | 0.0794 | 0.0711 | 0.7274 | 0.7607 | 0.0001 | 0.0000 | 0.0007 | 0.0005 | 0.0014 | 0.0028 | 0.0130 | 0.0161 | 0.0580 | 0.0627 | 0.1058 | 0.1260 | 0.0772 | 0.0841 | 0.1033 | 0.1156 | 0.6404 | 0.5922 | 0.0000 | 0.0009 | 0.0017 | 0.0096 | 0.0496 | 0.0965 | 0.0657 | 0.0897 | 0.6863 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 454 | 777 | | 7409 | 17484 | 322.3 | 67.54 | 205.37 | 234.69 | 243 | 264 | 279 | 296 | 313 | 331 | 353 | 381 | 419 | 0.0565 | 988 | 1.214 | 100.09 | 46.32 | 1 | 0.0378 | 280 | 0.0005 | 88.54 | 7.749 | 0.1264 | 108444.0 | 38100000 | 13900000000 | 5270000000000 | 0.4118 | 0.2358 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0027 | 0.0000 | 0.0126 | 0.0013 | 0.0653 | 0.0133 | 0.1407 | 0.0324 | 0.1465 | 0.0319 | 0.1766 | 0.0542 | 0.4551 | 0.8669 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0040 | 0.0001 | 0.0306 | 0.0082 | 0.0657 | 0.0178 | 0.0679 | 0.0118 | 0.0977 | 0.0245 | 0.7329 | 0.9376 | 0.0029 | 0.0057 | 0.0029 | 0.0172 | 0.0155 | 0.0602 | 0.0472 | 0.0888 | 0.1282 | 0.1977 | 0.1643 | 0.1748 | 0.1157 | 0.1175 | 0.1400 | 0.1547 | 0.3832 | 0.1834 | 0.0024 | 0.0027 | 0.0054 | 0.0338 | 0.0764 | 0.1255 | 0.0940 | 0.1234 | 0.5364 | 11 | 14 | 17 | 31 | 88 | 192 | 303 | 420 | 566 | 0.0364 | 50.81 | 5.936 | 0.4194 | 97252.5 | 57300000 | 38200000000 | 27900000000000 | 0.4410 | 0.1792 | 0.0679 | 0.0012 | 0.2334 | 0.0148 | 0.3166 | 0.1561 | 0.1663 | 0.2149 | 0.0900 | 0.2129 | 0.0748 | 0.1752 | 0.0282 | 0.0907 | 0.0175 | 0.0767 | 0.0053 | 0.0576 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0013 | 0.0006 | 0.0070 | 0.0062 | 0.0449 | 0.0360 | 0.0791 | 0.0719 | 0.0574 | 0.0536 | 0.0936 | 0.0726 | 0.7161 | 0.7591 | 0.0000 | 0.0007 | 0.0007 | 0.0016 | 0.0023 | 0.0042 | 0.0126 | 0.0140 | 0.0555 | 0.0663 | 0.0963 | 0.1117 | 0.0864 | 0.0871 | 0.1164 | 0.1189 | 0.6299 | 0.5955 | 0.0003 | 0.0013 | 0.0012 | 0.0113 | 0.0518 | 0.0818 | 0.0742 | 0.1052 | 0.6728 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 640 | 647 | | 6376 | 20211 | 467.1 | 97.26 | 74.59 | 104.47 | 355 | 384 | 407 | 429 | 451 | 477 | 504 | 541 | 602 | 0.0495 | 1000 | 0.965 | 107.82 | 31.58 | 1 | 0.0402 | 256 | 0.0008 | 48.43 | 7.332 | 0.1727 | 227685.0 | 116000000 | 61700000000 | 34200000000000 | 0.4323 | 0.2096 | 0.0005 | 0.0000 | 0.0005 | 0.0002 | 0.0030 | 0.0000 | 0.0118 | 0.0013 | 0.0469 | 0.0161 | 0.0999 | 0.0336 | 0.1154 | 0.0239 | 0.1501 | 0.0351 | 0.5720 | 0.8897 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0063 | 0.0002 | 0.0211 | 0.0111 | 0.0446 | 0.0196 | 0.0504 | 0.0108 | 0.0759 | 0.0166 | 0.7993 | 0.9416 | 0.0039 | 0.0000 | 0.0068 | 0.0084 | 0.0193 | 0.0169 | 0.0501 | 0.0478 | 0.1157 | 0.1348 | 0.1533 | 0.1573 | 0.0984 | 0.1152 | 0.1215 | 0.1348 | 0.4311 | 0.3848 | 0.0004 | 0.0014 | 0.0086 | 0.0280 | 0.0714 | 0.1288 | 0.1065 | 0.1352 | 0.5197 | 7 | 8 | 9 | 11 | 16 | 39 | 83 | 140 | 227 | 0.1404 | 11.27 | 4.303 | 0.6000 | 16476.9 | 5110000 | 1900000000 | 803000000000 | 0.4799 | 0.1508 | 0.0373 | 0.0004 | 0.1664 | 0.0126 | 0.2806 | 0.0605 | 0.1730 | 0.1438 | 0.1498 | 0.2138 | 0.1068 | 0.2197 | 0.0397 | 0.1363 | 0.0281 | 0.1023 | 0.0182 | 0.1106 | 0.0003 | 0.0001 | 0.0003 | 0.0006 | 0.0006 | 0.0010 | 0.0070 | 0.0080 | 0.0388 | 0.0338 | 0.0642 | 0.0584 | 0.0456 | 0.0429 | 0.0655 | 0.0588 | 0.7778 | 0.7963 | 0.0000 | 0.0010 | 0.0005 | 0.0002 | 0.0012 | 0.0013 | 0.0093 | 0.0155 | 0.0514 | 0.0530 | 0.0784 | 0.0890 | 0.0588 | 0.0718 | 0.0916 | 0.0918 | 0.7088 | 0.6764 | 0.0000 | 0.0000 | 0.0019 | 0.0069 | 0.0418 | 0.0702 | 0.0519 | 0.0787 | 0.7487 | ||
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 234 | 799 | | 13982 | 47347 | 267.6 | 72.72 | 111.48 | 151.15 | 180 | 206 | 227 | 244 | 261 | 277 | 298 | 324 | 366 | 0.0290 | 1375 | 0.637 | 134.38 | 29.41 | 4 | 0.0255 | 356 | 0.0013 | 25.91 | 6.963 | 0.2170 | 76872.3 | 23600000 | 7750000000 | 2700000000000 | 0.4326 | 0.2214 | 0.0001 | 0.0000 | 0.0013 | 0.0001 | 0.0055 | 0.0004 | 0.0221 | 0.0029 | 0.0806 | 0.0231 | 0.1501 | 0.0550 | 0.1533 | 0.0526 | 0.1827 | 0.0775 | 0.4043 | 0.7885 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0002 | 0.0076 | 0.0010 | 0.0363 | 0.0137 | 0.0660 | 0.0277 | 0.0623 | 0.0230 | 0.0865 | 0.0394 | 0.7392 | 0.8952 | 0.0052 | 0.0034 | 0.0097 | 0.0101 | 0.0207 | 0.0151 | 0.0446 | 0.0772 | 0.1034 | 0.1394 | 0.1383 | 0.2065 | 0.0906 | 0.0999 | 0.1317 | 0.1360 | 0.4557 | 0.3123 | 0.0005 | 0.0028 | 0.0097 | 0.0328 | 0.0738 | 0.1215 | 0.0977 | 0.1158 | 0.5454 | 7 | 9 | 11 | 16 | 39 | 79 | 133 | 204 | 314 | 0.0819 | 10.81 | 4.504 | 0.5328 | 35272.3 | 16700000 | 10300000000 | 7940000000000 | 0.3283 | 0.3071 | 0.0637 | 0.0018 | 0.1924 | 0.0219 | 0.2593 | 0.1299 | 0.1590 | 0.1336 | 0.1409 | 0.1843 | 0.0919 | 0.1786 | 0.0492 | 0.1220 | 0.0306 | 0.1122 | 0.0130 | 0.1156 | 0.0001 | 0.0000 | 0.0004 | 0.0004 | 0.0007 | 0.0005 | 0.0071 | 0.0063 | 0.0513 | 0.0394 | 0.0875 | 0.0698 | 0.0707 | 0.0553 | 0.1096 | 0.0865 | 0.6726 | 0.7417 | 0.0003 | 0.0002 | 0.0010 | 0.0011 | 0.0030 | 0.0057 | 0.0155 | 0.0207 | 0.0717 | 0.0816 | 0.1258 | 0.1367 | 0.0873 | 0.0954 | 0.1313 | 0.1337 | 0.5642 | 0.5249 | 0.0001 | 0.0005 | 0.0021 | 0.0105 | 0.0627 | 0.1064 | 0.0809 | 0.1220 | 0.6149 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 776 | 533 | | 11980 | 33861 | 383.5 | 82.50 | 120.63 | 176.56 | 283 | 310 | 334 | 355 | 376 | 398 | 421 | 451 | 496 | 0.0356 | 1205 | 1.136 | 140.66 | 55.15 | 1 | 0.0313 | 375 | 0.0009 | 37.01 | 7.234 | 0.1929 | 153867.0 | 64500000 | 28200000000 | 12800000000000 | 0.4493 | 0.2003 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0028 | 0.0000 | 0.0182 | 0.0008 | 0.0630 | 0.0134 | 0.1320 | 0.0320 | 0.1379 | 0.0333 | 0.1599 | 0.0519 | 0.4853 | 0.8686 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0010 | 0.0000 | 0.0076 | 0.0001 | 0.0277 | 0.0090 | 0.0540 | 0.0170 | 0.0581 | 0.0126 | 0.0745 | 0.0212 | 0.7764 | 0.9401 | 0.0019 | 0.0113 | 0.0047 | 0.0244 | 0.0159 | 0.0357 | 0.0637 | 0.1429 | 0.1404 | 0.1560 | 0.1807 | 0.2237 | 0.1147 | 0.0977 | 0.1470 | 0.1278 | 0.3310 | 0.1805 | 0.0004 | 0.0018 | 0.0069 | 0.0208 | 0.0738 | 0.1090 | 0.1005 | 0.1337 | 0.5532 | 7 | 8 | 10 | 13 | 28 | 71 | 135 | 223 | 358 | 0.1025 | 9.69 | 4.335 | 0.5557 | 45723.5 | 25300000 | 17600000000 | 14200000000000 | 0.3892 | 0.2409 | 0.0580 | 0.0013 | 0.2129 | 0.0223 | 0.2772 | 0.1129 | 0.1731 | 0.1468 | 0.1215 | 0.2079 | 0.0876 | 0.1983 | 0.0398 | 0.1203 | 0.0207 | 0.0982 | 0.0093 | 0.0921 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0008 | 0.0004 | 0.0071 | 0.0056 | 0.0520 | 0.0410 | 0.0868 | 0.0707 | 0.0678 | 0.0584 | 0.0917 | 0.0804 | 0.6937 | 0.7434 | 0.0005 | 0.0002 | 0.0012 | 0.0009 | 0.0018 | 0.0021 | 0.0154 | 0.0152 | 0.0663 | 0.0760 | 0.1097 | 0.1251 | 0.0819 | 0.0859 | 0.1104 | 0.1159 | 0.6128 | 0.5786 | 0.0001 | 0.0003 | 0.0013 | 0.0107 | 0.0581 | 0.1011 | 0.0739 | 0.1012 | 0.6533 |
| SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1207 | 207 | | 6980 | 19624 | 335.7 | 74.32 | 299.24 | 411.18 | 218 | 282 | 315 | 337 | 355 | 370 | 382 | 395 | 412 | 0.0495 | 972 | 0.878 | 105.01 | 22.67 | 2 | 0.0338 | 236 | 0.0016 | 18.87 | 6.802 | 0.2595 | 118201.0 | 43000000 | 16000000000 | 6030000000000 | 0.3992 | 0.2312 | 0.0008 | 0.0000 | 0.0019 | 0.0000 | 0.0057 | 0.0000 | 0.0151 | 0.0005 | 0.0362 | 0.0109 | 0.0496 | 0.0198 | 0.0603 | 0.0114 | 0.1042 | 0.0181 | 0.7262 | 0.9392 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0005 | 0.0117 | 0.0106 | 0.0200 | 0.0197 | 0.0164 | 0.0105 | 0.0219 | 0.0154 | 0.9264 | 0.9434 | 0.0234 | 0.1429 | 0.0263 | 0.0000 | 0.0536 | 0.4286 | 0.0623 | 0.2857 | 0.0837 | 0.1429 | 0.1003 | 0.0000 | 0.1120 | 0.0000 | 0.1324 | 0.0000 | 0.4060 | 0.0000 | 0.0007 | 0.0016 | 0.0028 | 0.0094 | 0.0211 | 0.0392 | 0.0446 | 0.0634 | 0.8170 | 12 | 16 | 20 | 28 | 78 | 180 | 350 | 599 | 943 | 0.0721 | 64.70 | 5.520 | 0.4930 | 258610.0 | 294000000 | 385000000000 | 559000000000000 | 0.4020 | 0.2305 | 0.0543 | 0.0023 | 0.2124 | 0.0098 | 0.3077 | 0.0976 | 0.1647 | 0.1574 | 0.1179 | 0.2237 | 0.0828 | 0.2003 | 0.0326 | 0.1140 | 0.0217 | 0.0910 | 0.0059 | 0.1039 | 0.0003 | 0.0000 | 0.0001 | 0.0001 | 0.0013 | 0.0004 | 0.0073 | 0.0059 | 0.0473 | 0.0415 | 0.0872 | 0.0708 | 0.0574 | 0.0514 | 0.0844 | 0.0737 | 0.7147 | 0.7561 | 0.0003 | 0.0002 | 0.0014 | 0.0008 | 0.0026 | 0.0025 | 0.0115 | 0.0140 | 0.0574 | 0.0661 | 0.1058 | 0.1190 | 0.0739 | 0.0814 | 0.1015 | 0.1092 | 0.6456 | 0.6068 | 0.0002 | 0.0005 | 0.0011 | 0.0070 | 0.0580 | 0.0920 | 0.0640 | 0.0926 | 0.6846 |