High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 293 | 422 | | 7600 | 17600 | 391.5 | 79.06 | 96.65 | 175.15 | 294 | 323 | 346 | 368 | 387 | 407 | 428 | 454 | 494 | 0.0666 | 1173 | 1.027 | 120.93 | 40.26 | 1 | 0.0393 | 299 | 0.0010 | 42.54 | 7.175 | 0.1809 | 159521.0 | 67600000 | 29700000000 | 13600000000000 | 0.4253 | 0.2170 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0029 | 0.0001 | 0.0171 | 0.0012 | 0.0549 | 0.0162 | 0.1019 | 0.0305 | 0.1266 | 0.0305 | 0.1577 | 0.0455 | 0.5378 | 0.8759 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0001 | 0.0070 | 0.0008 | 0.0228 | 0.0109 | 0.0451 | 0.0198 | 0.0570 | 0.0134 | 0.0686 | 0.0214 | 0.7973 | 0.9336 | 0.0076 | 0.0156 | 0.0143 | 0.0430 | 0.0227 | 0.0352 | 0.0714 | 0.1211 | 0.1294 | 0.1953 | 0.1723 | 0.2305 | 0.1445 | 0.1367 | 0.1437 | 0.0977 | 0.2941 | 0.1250 | 0.0016 | 0.0033 | 0.0068 | 0.0256 | 0.0698 | 0.1192 | 0.1121 | 0.1367 | 0.5248 | 7 | 8 | 10 | 12 | 15 | 25 | 57 | 139 | 334 | 0.1858 | 26.15 | 3.861 | 0.6358 | 40015.7 | 24500000 | 18000000000 | 15000000000000 | 0.4382 | 0.1915 | 0.0832 | 0.0054 | 0.2774 | 0.0380 | 0.2825 | 0.1739 | 0.1261 | 0.1618 | 0.0870 | 0.2101 | 0.0542 | 0.1540 | 0.0429 | 0.0936 | 0.0366 | 0.0713 | 0.0101 | 0.0918 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0011 | 0.0015 | 0.0121 | 0.0107 | 0.0607 | 0.0574 | 0.0962 | 0.0804 | 0.0626 | 0.0563 | 0.0962 | 0.0923 | 0.6700 | 0.7009 | 0.0000 | 0.0003 | 0.0005 | 0.0003 | 0.0023 | 0.0006 | 0.0143 | 0.0109 | 0.0696 | 0.0836 | 0.1222 | 0.1310 | 0.0703 | 0.0729 | 0.1126 | 0.1203 | 0.6081 | 0.5802 | 0.0000 | 0.0007 | 0.0012 | 0.0145 | 0.0655 | 0.1071 | 0.0700 | 0.1014 | 0.6396 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1119 | 214 | | 5751 | 20046 | 238.3 | 49.59 | 123.21 | 136.16 | 178 | 195 | 208 | 220 | 233 | 246 | 261 | 280 | 308 | 0.0535 | 1073 | 0.956 | 183.13 | 46.27 | 1 | 0.0753 | 433 | 0.0009 | 46.08 | 7.198 | 0.1709 | 59261.6 | 15400000 | 4150000000 | 1160000000000 | 0.4175 | 0.2356 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0035 | 0.0005 | 0.0192 | 0.0024 | 0.0653 | 0.0160 | 0.1455 | 0.0388 | 0.1466 | 0.0377 | 0.1807 | 0.0616 | 0.4387 | 0.8430 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0005 | 0.0067 | 0.0007 | 0.0275 | 0.0110 | 0.0670 | 0.0243 | 0.0630 | 0.0150 | 0.0867 | 0.0246 | 0.7466 | 0.9238 | 0.0059 | 0.0172 | 0.0109 | 0.0515 | 0.0158 | 0.1030 | 0.0732 | 0.1373 | 0.1464 | 0.2232 | 0.1771 | 0.1588 | 0.1207 | 0.0944 | 0.1563 | 0.0987 | 0.2938 | 0.1159 | 0.0023 | 0.0026 | 0.0079 | 0.0350 | 0.0801 | 0.1287 | 0.1072 | 0.1317 | 0.5045 | 9 | 12 | 16 | 32 | 68 | 116 | 169 | 230 | 320 | 0.0565 | 15.55 | 5.256 | 0.4785 | 33719.5 | 12300000 | 5330000000 | 2640000000000 | 0.4071 | 0.2119 | 0.0276 | 0.0010 | 0.1314 | 0.0064 | 0.2324 | 0.0484 | 0.2178 | 0.1001 | 0.1708 | 0.1763 | 0.1189 | 0.2178 | 0.0605 | 0.1609 | 0.0281 | 0.1323 | 0.0124 | 0.1568 | 0.0001 | 0.0000 | 0.0005 | 0.0005 | 0.0020 | 0.0009 | 0.0121 | 0.0082 | 0.0395 | 0.0341 | 0.0660 | 0.0575 | 0.0579 | 0.0452 | 0.0777 | 0.0695 | 0.7443 | 0.7842 | 0.0004 | 0.0007 | 0.0012 | 0.0015 | 0.0041 | 0.0051 | 0.0158 | 0.0229 | 0.0539 | 0.0569 | 0.0854 | 0.0956 | 0.0750 | 0.0817 | 0.1018 | 0.1010 | 0.6624 | 0.6347 | 0.0003 | 0.0013 | 0.0027 | 0.0126 | 0.0464 | 0.0749 | 0.0671 | 0.0897 | 0.7050 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 844 | 729 | | 5195 | 6746 | 513.2 | 118.34 | 131.41 | 201.76 | 374 | 422 | 455 | 484 | 509 | 533 | 559 | 598 | 663 | 0.1269 | 856 | 1.179 | 136.50 | 52.00 | 4 | 0.0670 | 348 | 0.0006 | 81.67 | 7.590 | 0.1403 | 277409.0 | 157000000 | 93300000000 | 57800000000000 | 0.4641 | 0.1828 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0092 | 0.0002 | 0.0187 | 0.0015 | 0.0728 | 0.0317 | 0.1260 | 0.0589 | 0.1091 | 0.0502 | 0.1534 | 0.0757 | 0.5108 | 0.7819 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0037 | 0.0008 | 0.0387 | 0.0254 | 0.0701 | 0.0404 | 0.0576 | 0.0258 | 0.0831 | 0.0416 | 0.7456 | 0.8661 | 0.0059 | 0.0100 | 0.0118 | 0.0134 | 0.0178 | 0.0334 | 0.0675 | 0.1104 | 0.1349 | 0.1371 | 0.1527 | 0.1605 | 0.0982 | 0.1171 | 0.1396 | 0.1371 | 0.3716 | 0.2809 | 0.0012 | 0.0020 | 0.0083 | 0.0313 | 0.0944 | 0.1583 | 0.1035 | 0.1432 | 0.4578 | 7 | 9 | 11 | 15 | 30 | 63 | 128 | 229 | 416 | 0.1248 | 27.25 | 4.487 | 0.5729 | 57968.2 | 37400000 | 29800000000 | 27700000000000 | 0.6421 | 0.0717 | 0.0374 | 0.0045 | 0.1828 | 0.0269 | 0.3106 | 0.1256 | 0.1806 | 0.1469 | 0.1564 | 0.2096 | 0.0639 | 0.2096 | 0.0419 | 0.1188 | 0.0176 | 0.0953 | 0.0088 | 0.0628 | 0.0000 | 0.0004 | 0.0004 | 0.0024 | 0.0009 | 0.0028 | 0.0121 | 0.0108 | 0.0689 | 0.0667 | 0.1123 | 0.0895 | 0.0671 | 0.0667 | 0.0988 | 0.0927 | 0.6395 | 0.6681 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0028 | 0.0050 | 0.0213 | 0.0292 | 0.0786 | 0.0856 | 0.1296 | 0.1290 | 0.0836 | 0.0862 | 0.1072 | 0.1141 | 0.5758 | 0.5509 | 0.0000 | 0.0010 | 0.0035 | 0.0180 | 0.0721 | 0.1181 | 0.0756 | 0.1086 | 0.6031 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 153 | 736 | | 17577 | 32431 | 213.5 | 66.22 | 119.98 | 191.83 | 136 | 158 | 175 | 190 | 206 | 224 | 243 | 267 | 300 | 0.0595 | 1929 | 0.787 | 314.94 | 107.02 | 13 | 0.0531 | 934 | 0.0006 | 60.12 | 7.718 | 0.1576 | 49951.2 | 12700000 | 3480000000 | 1030000000000 | 0.4279 | 0.2038 | 0.0008 | 0.0001 | 0.0017 | 0.0000 | 0.0105 | 0.0012 | 0.0391 | 0.0061 | 0.0988 | 0.0278 | 0.1631 | 0.0552 | 0.1671 | 0.0671 | 0.1808 | 0.0927 | 0.3382 | 0.7498 | 0.0004 | 0.0001 | 0.0009 | 0.0000 | 0.0031 | 0.0002 | 0.0119 | 0.0026 | 0.0325 | 0.0130 | 0.0602 | 0.0251 | 0.0610 | 0.0279 | 0.0802 | 0.0411 | 0.7497 | 0.8899 | 0.0021 | 0.0077 | 0.0056 | 0.0131 | 0.0162 | 0.0219 | 0.0440 | 0.0848 | 0.0899 | 0.1297 | 0.1362 | 0.1822 | 0.1144 | 0.1160 | 0.1320 | 0.1510 | 0.4596 | 0.2938 | 0.0007 | 0.0020 | 0.0072 | 0.0280 | 0.0589 | 0.0957 | 0.0855 | 0.1131 | 0.6090 | 12 | 15 | 17 | 19 | 25 | 43 | 91 | 197 | 387 | 0.1336 | 21.39 | 4.248 | 0.6174 | 51191.5 | 32500000 | 25000000000 | 21700000000000 | 0.5704 | 0.1134 | 0.0562 | 0.0029 | 0.1967 | 0.0294 | 0.2199 | 0.1289 | 0.1503 | 0.1471 | 0.1472 | 0.1759 | 0.1038 | 0.1638 | 0.0562 | 0.1096 | 0.0452 | 0.1055 | 0.0244 | 0.1370 | 0.0001 | 0.0003 | 0.0006 | 0.0007 | 0.0023 | 0.0022 | 0.0121 | 0.0103 | 0.0469 | 0.0439 | 0.0761 | 0.0620 | 0.0514 | 0.0494 | 0.0790 | 0.0736 | 0.7315 | 0.7577 | 0.0001 | 0.0003 | 0.0009 | 0.0010 | 0.0024 | 0.0040 | 0.0148 | 0.0174 | 0.0598 | 0.0709 | 0.0992 | 0.1012 | 0.0685 | 0.0794 | 0.1031 | 0.1055 | 0.6513 | 0.6204 | 0.0001 | 0.0002 | 0.0016 | 0.0130 | 0.0555 | 0.0840 | 0.0645 | 0.0934 | 0.6877 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1097 | 401 | | 5619 | 10511 | 100.4 | 25.69 | 150.94 | 167.26 | 71 | 79 | 86 | 92 | 97 | 103 | 110 | 119 | 132 | 0.0786 | 826 | 0.983 | 96.05 | 27.31 | 1 | 0.0418 | 235 | 0.0033 | 15.27 | 6.069 | 0.2967 | 10734.1 | 1230000 | 151000000 | 19900000000 | 0.4514 | 0.2026 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0093 | 0.0000 | 0.0335 | 0.0025 | 0.0924 | 0.0231 | 0.1475 | 0.0450 | 0.1673 | 0.0550 | 0.1991 | 0.0865 | 0.3487 | 0.7879 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0018 | 0.0000 | 0.0089 | 0.0002 | 0.0392 | 0.0149 | 0.0643 | 0.0223 | 0.0770 | 0.0225 | 0.1061 | 0.0415 | 0.7020 | 0.8987 | 0.0103 | 0.0074 | 0.0197 | 0.0245 | 0.0310 | 0.0515 | 0.0874 | 0.0711 | 0.1400 | 0.1985 | 0.1805 | 0.1642 | 0.1184 | 0.1201 | 0.1391 | 0.1569 | 0.2735 | 0.2059 | 0.0012 | 0.0051 | 0.0125 | 0.0446 | 0.0896 | 0.1405 | 0.1151 | 0.1526 | 0.4387 | 11 | 17 | 32 | 53 | 79 | 117 | 181 | 290 | 415 | 0.0097 | 71.41 | 6.470 | 0.3608 | 50757.6 | 22700000 | 11700000000 | 6580000000000 | 0.5255 | 0.1681 | 0.0205 | 0.0024 | 0.1212 | 0.0122 | 0.2269 | 0.0538 | 0.1561 | 0.1204 | 0.1448 | 0.1703 | 0.1458 | 0.1689 | 0.0791 | 0.1385 | 0.0565 | 0.1434 | 0.0493 | 0.1899 | 0.0005 | 0.0004 | 0.0015 | 0.0008 | 0.0056 | 0.0018 | 0.0121 | 0.0135 | 0.0522 | 0.0488 | 0.0869 | 0.0725 | 0.0689 | 0.0674 | 0.0959 | 0.0926 | 0.6765 | 0.7021 | 0.0000 | 0.0007 | 0.0022 | 0.0011 | 0.0060 | 0.0049 | 0.0133 | 0.0226 | 0.0616 | 0.0560 | 0.1042 | 0.1173 | 0.0801 | 0.0920 | 0.1087 | 0.1117 | 0.6238 | 0.5937 | 0.0014 | 0.0025 | 0.0061 | 0.0150 | 0.0574 | 0.0872 | 0.0738 | 0.0955 | 0.6611 | ||
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1219 | 611 | | 6727 | 10795 | 500.4 | 87.18 | 61.57 | 164.61 | 389 | 436 | 464 | 484 | 500 | 519 | 539 | 564 | 613 | 0.0766 | 827 | 0.887 | 151.21 | 35.90 | 4 | 0.0523 | 352 | 0.0010 | 40.11 | 7.197 | 0.1973 | 258004.0 | 137000000 | 74100000000 | 41200000000000 | 0.4599 | 0.1961 | 0.0006 | 0.0000 | 0.0008 | 0.0000 | 0.0006 | 0.0000 | 0.0061 | 0.0005 | 0.0334 | 0.0138 | 0.0743 | 0.0305 | 0.0688 | 0.0200 | 0.0981 | 0.0361 | 0.7174 | 0.8992 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0002 | 0.0203 | 0.0122 | 0.0431 | 0.0268 | 0.0321 | 0.0141 | 0.0475 | 0.0242 | 0.8540 | 0.9226 | 0.0036 | 0.0385 | 0.0109 | 0.0641 | 0.0243 | 0.0256 | 0.0510 | 0.1282 | 0.0875 | 0.2179 | 0.1179 | 0.2179 | 0.0899 | 0.1026 | 0.1118 | 0.1026 | 0.5030 | 0.1026 | 0.0015 | 0.0026 | 0.0100 | 0.0280 | 0.0665 | 0.1130 | 0.0971 | 0.1266 | 0.5546 | 5 | 5 | 7 | 8 | 9 | 10 | 12 | 20 | 145 | 0.3474 | 14.59 | 2.480 | 0.7590 | 30885.0 | 22100000 | 18100000000 | 16500000000000 | 0.6221 | 0.0747 | 0.0404 | 0.0026 | 0.1515 | 0.0289 | 0.2172 | 0.0525 | 0.2071 | 0.1732 | 0.1515 | 0.2310 | 0.1414 | 0.2047 | 0.0505 | 0.1260 | 0.0303 | 0.0866 | 0.0101 | 0.0945 | 0.0000 | 0.0006 | 0.0006 | 0.0030 | 0.0032 | 0.0024 | 0.0121 | 0.0119 | 0.0401 | 0.0351 | 0.0650 | 0.0660 | 0.0510 | 0.0463 | 0.0643 | 0.0564 | 0.7637 | 0.7784 | 0.0000 | 0.0000 | 0.0015 | 0.0015 | 0.0015 | 0.0038 | 0.0175 | 0.0215 | 0.0445 | 0.0445 | 0.0729 | 0.0722 | 0.0590 | 0.0507 | 0.0649 | 0.0753 | 0.7383 | 0.7304 | 0.0000 | 0.0014 | 0.0020 | 0.0143 | 0.0442 | 0.0626 | 0.0558 | 0.0721 | 0.7476 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 550 | 588 | | 3961 | 12702 | 362.6 | 74.74 | 145.47 | 313.98 | 267 | 301 | 325 | 344 | 362 | 380 | 400 | 423 | 452 | 0.0624 | 793 | 1.103 | 133.51 | 42.58 | 1 | 0.0836 | 331 | 0.0009 | 60.00 | 7.202 | 0.1727 | 137032.0 | 53800000 | 22000000000 | 9300000000000 | 0.4189 | 0.2240 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0191 | 0.0008 | 0.0484 | 0.0174 | 0.0949 | 0.0441 | 0.1019 | 0.0284 | 0.1484 | 0.0412 | 0.5837 | 0.8681 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0067 | 0.0008 | 0.0179 | 0.0148 | 0.0363 | 0.0309 | 0.0312 | 0.0140 | 0.0515 | 0.0197 | 0.8556 | 0.9198 | 0.0035 | 0.0177 | 0.0209 | 0.0088 | 0.0435 | 0.0796 | 0.1009 | 0.1504 | 0.1687 | 0.1770 | 0.1965 | 0.2566 | 0.1287 | 0.0442 | 0.1270 | 0.1150 | 0.2104 | 0.1504 | 0.0015 | 0.0025 | 0.0066 | 0.0207 | 0.0673 | 0.1037 | 0.0967 | 0.1463 | 0.5547 | 8 | 11 | 14 | 21 | 33 | 53 | 90 | 169 | 374 | 0.0996 | 33.81 | 4.438 | 0.6074 | 119740.0 | 178000000 | 330000000000 | 679000000000000 | 0.4919 | 0.1485 | 0.0193 | 0.0012 | 0.1035 | 0.0094 | 0.2190 | 0.0528 | 0.2154 | 0.0944 | 0.2106 | 0.1812 | 0.1408 | 0.2223 | 0.0590 | 0.1554 | 0.0217 | 0.1384 | 0.0108 | 0.1449 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0018 | 0.0021 | 0.0121 | 0.0100 | 0.0667 | 0.0554 | 0.1113 | 0.0915 | 0.0640 | 0.0610 | 0.0969 | 0.0879 | 0.6473 | 0.6909 | 0.0000 | 0.0005 | 0.0024 | 0.0064 | 0.0064 | 0.0055 | 0.0189 | 0.0132 | 0.0781 | 0.0783 | 0.1305 | 0.1429 | 0.0673 | 0.0660 | 0.0995 | 0.1051 | 0.5969 | 0.5822 | 0.0003 | 0.0007 | 0.0031 | 0.0146 | 0.0809 | 0.1122 | 0.0729 | 0.0983 | 0.6170 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 680 | 551 | | 5987 | 6093 | 134.6 | 38.08 | 176.05 | 235.22 | 92 | 104 | 113 | 122 | 129 | 138 | 148 | 161 | 182 | 0.1188 | 724 | 1.000 | 95.60 | 29.27 | 1 | 0.0403 | 241 | 0.0020 | 24.09 | 6.532 | 0.2581 | 19556.5 | 3090000 | 540000000 | 105000000000 | 0.4491 | 0.2026 | 0.0006 | 0.0000 | 0.0035 | 0.0004 | 0.0088 | 0.0006 | 0.0253 | 0.0021 | 0.0823 | 0.0225 | 0.1531 | 0.0497 | 0.1611 | 0.0584 | 0.1743 | 0.0871 | 0.3909 | 0.7792 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0031 | 0.0000 | 0.0090 | 0.0005 | 0.0374 | 0.0132 | 0.0593 | 0.0258 | 0.0654 | 0.0231 | 0.0842 | 0.0390 | 0.7408 | 0.8984 | 0.0009 | 0.0104 | 0.0128 | 0.0084 | 0.0239 | 0.0251 | 0.0632 | 0.0898 | 0.1376 | 0.1962 | 0.1709 | 0.1649 | 0.1043 | 0.1211 | 0.1564 | 0.1608 | 0.3299 | 0.2234 | 0.0023 | 0.0023 | 0.0095 | 0.0338 | 0.0834 | 0.1244 | 0.1085 | 0.1301 | 0.5059 | 10 | 11 | 13 | 16 | 34 | 115 | 229 | 352 | 553 | 0.1116 | 42.16 | 4.818 | 0.5374 | 86309.7 | 54700000 | 39600000000 | 31400000000000 | 0.5384 | 0.1532 | 0.0884 | 0.0052 | 0.2601 | 0.0551 | 0.2652 | 0.1627 | 0.1288 | 0.1890 | 0.0833 | 0.2008 | 0.0758 | 0.1444 | 0.0581 | 0.0866 | 0.0227 | 0.0735 | 0.0177 | 0.0827 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0020 | 0.0121 | 0.0068 | 0.0484 | 0.0419 | 0.0963 | 0.0971 | 0.0652 | 0.0532 | 0.0963 | 0.0789 | 0.6799 | 0.7201 | 0.0000 | 0.0006 | 0.0016 | 0.0017 | 0.0021 | 0.0058 | 0.0172 | 0.0221 | 0.0667 | 0.0813 | 0.1199 | 0.1371 | 0.0896 | 0.0936 | 0.1214 | 0.1174 | 0.5816 | 0.5404 | 0.0000 | 0.0014 | 0.0023 | 0.0136 | 0.0567 | 0.1068 | 0.0829 | 0.1036 | 0.6326 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 718 | 209 | | 6919 | 20153 | 439.9 | 83.94 | 59.12 | 60.79 | 328 | 364 | 393 | 418 | 442 | 465 | 486 | 511 | 544 | 0.0555 | 1118 | 1.097 | 116.93 | 36.89 | 1 | 0.0405 | 280 | 0.0010 | 31.34 | 7.121 | 0.1942 | 200514.0 | 94500000 | 45900000000 | 23000000000000 | 0.3868 | 0.2525 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0000 | 0.0112 | 0.0015 | 0.0437 | 0.0118 | 0.0766 | 0.0244 | 0.0951 | 0.0209 | 0.1280 | 0.0268 | 0.6427 | 0.9146 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0013 | 0.0171 | 0.0100 | 0.0281 | 0.0194 | 0.0344 | 0.0128 | 0.0426 | 0.0172 | 0.8730 | 0.9393 | 0.0040 | 0.0086 | 0.0081 | 0.0000 | 0.0424 | 0.0259 | 0.0727 | 0.2586 | 0.1354 | 0.0862 | 0.1687 | 0.1810 | 0.1343 | 0.1293 | 0.1384 | 0.0431 | 0.2960 | 0.2672 | 0.0003 | 0.0014 | 0.0020 | 0.0108 | 0.0519 | 0.0935 | 0.0896 | 0.1278 | 0.6227 | 8 | 10 | 14 | 25 | 40 | 57 | 76 | 99 | 135 | 0.0457 | 4.18 | 4.483 | 0.5799 | 7190.4 | 1330000 | 338000000 | 109000000000 | 0.4299 | 0.1814 | 0.0071 | 0.0015 | 0.0560 | 0.0042 | 0.1504 | 0.0171 | 0.2041 | 0.0543 | 0.2237 | 0.1277 | 0.1653 | 0.2005 | 0.1077 | 0.1668 | 0.0611 | 0.1704 | 0.0247 | 0.2575 | 0.0002 | 0.0001 | 0.0009 | 0.0008 | 0.0023 | 0.0018 | 0.0122 | 0.0087 | 0.0364 | 0.0271 | 0.0609 | 0.0475 | 0.0552 | 0.0389 | 0.0755 | 0.0611 | 0.7565 | 0.8141 | 0.0011 | 0.0011 | 0.0026 | 0.0037 | 0.0041 | 0.0073 | 0.0192 | 0.0257 | 0.0575 | 0.0690 | 0.0847 | 0.1021 | 0.0802 | 0.0802 | 0.1038 | 0.1182 | 0.6468 | 0.5927 | 0.0005 | 0.0010 | 0.0038 | 0.0132 | 0.0444 | 0.0754 | 0.0604 | 0.0891 | 0.7123 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 688 | 324 | | 13758 | 21485 | 122.6 | 40.36 | 202.58 | 231.30 | 76 | 90 | 98 | 107 | 117 | 128 | 141 | 156 | 178 | 0.0872 | 1874 | 0.692 | 86.83 | 17.09 | 4 | 0.0151 | 208 | 0.0009 | 37.58 | 7.369 | 0.2047 | 16661.6 | 2480000 | 400000000 | 69100000000 | 0.4692 | 0.2051 | 0.0024 | 0.0004 | 0.0062 | 0.0006 | 0.0139 | 0.0027 | 0.0405 | 0.0084 | 0.0991 | 0.0326 | 0.1598 | 0.0715 | 0.1633 | 0.0626 | 0.1771 | 0.0877 | 0.3378 | 0.7336 | 0.0011 | 0.0002 | 0.0029 | 0.0003 | 0.0047 | 0.0010 | 0.0145 | 0.0048 | 0.0370 | 0.0172 | 0.0555 | 0.0390 | 0.0585 | 0.0291 | 0.0729 | 0.0411 | 0.7528 | 0.8673 | 0.0020 | 0.0037 | 0.0072 | 0.0067 | 0.0133 | 0.0209 | 0.0372 | 0.0491 | 0.0847 | 0.1098 | 0.1175 | 0.1589 | 0.0893 | 0.1141 | 0.1233 | 0.1387 | 0.5255 | 0.3982 | 0.0010 | 0.0026 | 0.0073 | 0.0221 | 0.0578 | 0.0893 | 0.0766 | 0.1021 | 0.6413 | 15 | 20 | 31 | 57 | 109 | 182 | 259 | 358 | 545 | 0.0237 | 41.98 | 5.971 | 0.4277 | 94535.6 | 60700000 | 46900000000 | 41300000000000 | 0.5071 | 0.1526 | 0.0324 | 0.0022 | 0.1222 | 0.0156 | 0.1953 | 0.0725 | 0.1804 | 0.1085 | 0.1681 | 0.1619 | 0.1340 | 0.1825 | 0.0858 | 0.1314 | 0.0495 | 0.1367 | 0.0324 | 0.1888 | 0.0001 | 0.0005 | 0.0017 | 0.0015 | 0.0035 | 0.0027 | 0.0122 | 0.0106 | 0.0577 | 0.0494 | 0.0901 | 0.0778 | 0.0671 | 0.0552 | 0.0932 | 0.0791 | 0.6743 | 0.7233 | 0.0003 | 0.0010 | 0.0028 | 0.0034 | 0.0068 | 0.0100 | 0.0237 | 0.0359 | 0.0811 | 0.0934 | 0.1246 | 0.1344 | 0.0910 | 0.0879 | 0.1214 | 0.1091 | 0.5482 | 0.5250 | 0.0005 | 0.0019 | 0.0048 | 0.0175 | 0.0673 | 0.1061 | 0.0788 | 0.1115 | 0.6117 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 425 | 828 | | 9686 | 14128 | 100.3 | 24.59 | 205.89 | 202.72 | 72 | 79 | 85 | 91 | 97 | 103 | 110 | 120 | 135 | 0.0773 | 1092 | 0.773 | 63.03 | 19.85 | 4 | 0.0184 | 178 | 0.0016 | 27.28 | 6.760 | 0.2225 | 10667.4 | 1200000 | 143000000 | 18000000000 | 0.4311 | 0.2206 | 0.0007 | 0.0000 | 0.0025 | 0.0002 | 0.0089 | 0.0003 | 0.0289 | 0.0048 | 0.0826 | 0.0210 | 0.1495 | 0.0494 | 0.1653 | 0.0539 | 0.1882 | 0.0764 | 0.3734 | 0.7940 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0043 | 0.0000 | 0.0130 | 0.0021 | 0.0319 | 0.0109 | 0.0542 | 0.0231 | 0.0628 | 0.0163 | 0.0885 | 0.0251 | 0.7438 | 0.9226 | 0.0040 | 0.0078 | 0.0106 | 0.0142 | 0.0227 | 0.0492 | 0.0721 | 0.1410 | 0.1245 | 0.1643 | 0.1668 | 0.2018 | 0.1285 | 0.1294 | 0.1346 | 0.1345 | 0.3362 | 0.1578 | 0.0028 | 0.0044 | 0.0131 | 0.0331 | 0.0776 | 0.1130 | 0.1075 | 0.1367 | 0.5119 | 19 | 33 | 57 | 89 | 132 | 192 | 271 | 367 | 509 | 0.0106 | 35.88 | 6.248 | 0.3841 | 83484.1 | 45100000 | 28900000000 | 21200000000000 | 0.5547 | 0.1227 | 0.0456 | 0.0027 | 0.1805 | 0.0154 | 0.2495 | 0.1234 | 0.1651 | 0.1270 | 0.1294 | 0.1710 | 0.1041 | 0.1743 | 0.0548 | 0.1294 | 0.0370 | 0.1093 | 0.0339 | 0.1475 | 0.0005 | 0.0004 | 0.0013 | 0.0010 | 0.0037 | 0.0030 | 0.0122 | 0.0118 | 0.0659 | 0.0511 | 0.1064 | 0.0942 | 0.0799 | 0.0639 | 0.1109 | 0.0947 | 0.6192 | 0.6799 | 0.0004 | 0.0013 | 0.0022 | 0.0030 | 0.0061 | 0.0106 | 0.0230 | 0.0300 | 0.0848 | 0.0881 | 0.1339 | 0.1427 | 0.0916 | 0.1017 | 0.1258 | 0.1334 | 0.5322 | 0.4892 | 0.0002 | 0.0030 | 0.0037 | 0.0199 | 0.0732 | 0.1163 | 0.0904 | 0.1209 | 0.5723 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1060 | 148 | | 9173 | 22344 | 294.9 | 54.87 | 142.27 | 167.42 | 227 | 246 | 262 | 276 | 290 | 304 | 321 | 343 | 371 | 0.0689 | 1540 | 0.872 | 128.71 | 44.38 | 1 | 0.0395 | 362 | 0.0007 | 53.70 | 7.461 | 0.1589 | 89976.7 | 28400000 | 9240000000 | 3100000000000 | 0.4189 | 0.2273 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0039 | 0.0000 | 0.0119 | 0.0010 | 0.0544 | 0.0105 | 0.1011 | 0.0239 | 0.1296 | 0.0218 | 0.1648 | 0.0345 | 0.5330 | 0.9084 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0059 | 0.0002 | 0.0246 | 0.0088 | 0.0420 | 0.0180 | 0.0587 | 0.0104 | 0.0811 | 0.0154 | 0.7860 | 0.9472 | 0.0035 | 0.0359 | 0.0110 | 0.0256 | 0.0311 | 0.0769 | 0.0876 | 0.1487 | 0.1090 | 0.1436 | 0.1739 | 0.1641 | 0.1256 | 0.1128 | 0.1387 | 0.1231 | 0.3195 | 0.1692 | 0.0012 | 0.0047 | 0.0077 | 0.0323 | 0.0798 | 0.1131 | 0.0949 | 0.1254 | 0.5411 | 14 | 17 | 22 | 39 | 72 | 114 | 176 | 260 | 379 | 0.0282 | 29.29 | 5.688 | 0.4480 | 48267.7 | 23800000 | 15100000000 | 12000000000000 | 0.5526 | 0.1273 | 0.0495 | 0.0023 | 0.1676 | 0.0182 | 0.2382 | 0.0872 | 0.1820 | 0.1262 | 0.1201 | 0.1819 | 0.1042 | 0.1777 | 0.0735 | 0.1315 | 0.0360 | 0.1131 | 0.0288 | 0.1618 | 0.0010 | 0.0004 | 0.0013 | 0.0008 | 0.0025 | 0.0027 | 0.0122 | 0.0114 | 0.0574 | 0.0459 | 0.1001 | 0.0810 | 0.0689 | 0.0643 | 0.0971 | 0.0872 | 0.6595 | 0.7063 | 0.0003 | 0.0003 | 0.0007 | 0.0013 | 0.0044 | 0.0053 | 0.0173 | 0.0217 | 0.0820 | 0.0881 | 0.1194 | 0.1360 | 0.0834 | 0.0891 | 0.1164 | 0.1154 | 0.5761 | 0.5428 | 0.0005 | 0.0013 | 0.0029 | 0.0153 | 0.0705 | 0.1085 | 0.0767 | 0.1091 | 0.6152 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 571 | 922 | | 4617 | 8322 | 491.0 | 95.75 | 198.40 | 274.48 | 372 | 405 | 431 | 459 | 485 | 511 | 541 | 573 | 621 | 0.0908 | 756 | 1.217 | 121.30 | 48.70 | 1 | 0.0682 | 315 | 0.0006 | 68.44 | 7.576 | 0.1426 | 250279.0 | 132000000 | 72100000000 | 40600000000000 | 0.4178 | 0.2313 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0002 | 0.0112 | 0.0025 | 0.0586 | 0.0169 | 0.1189 | 0.0373 | 0.1287 | 0.0263 | 0.1587 | 0.0443 | 0.5217 | 0.8725 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0064 | 0.0011 | 0.0309 | 0.0133 | 0.0554 | 0.0279 | 0.0492 | 0.0168 | 0.0717 | 0.0251 | 0.7855 | 0.9157 | 0.0040 | 0.0000 | 0.0081 | 0.0000 | 0.0256 | 0.0000 | 0.0823 | 0.0000 | 0.1107 | 0.0000 | 0.1741 | 0.0000 | 0.1039 | 0.0000 | 0.1323 | 0.0000 | 0.3590 | 0.0000 | 0.0005 | 0.0023 | 0.0059 | 0.0244 | 0.0765 | 0.1199 | 0.0851 | 0.1231 | 0.5624 | 15 | 20 | 25 | 38 | 68 | 118 | 188 | 348 | 633 | 0.0340 | 31.16 | 5.359 | 0.5201 | 114691.0 | 92700000 | 87100000000 | 90400000000000 | 0.3987 | 0.2243 | 0.0214 | 0.0007 | 0.1193 | 0.0152 | 0.2370 | 0.0550 | 0.1330 | 0.0774 | 0.1361 | 0.1527 | 0.1055 | 0.2069 | 0.0826 | 0.1122 | 0.0841 | 0.1165 | 0.0810 | 0.2634 | 0.0004 | 0.0003 | 0.0029 | 0.0015 | 0.0022 | 0.0021 | 0.0122 | 0.0114 | 0.0561 | 0.0418 | 0.0820 | 0.0749 | 0.0557 | 0.0523 | 0.0805 | 0.0737 | 0.7080 | 0.7419 | 0.0005 | 0.0000 | 0.0014 | 0.0010 | 0.0056 | 0.0031 | 0.0118 | 0.0118 | 0.0592 | 0.0536 | 0.0870 | 0.1050 | 0.0602 | 0.0551 | 0.0827 | 0.0881 | 0.6916 | 0.6823 | 0.0008 | 0.0017 | 0.0033 | 0.0124 | 0.0541 | 0.0880 | 0.0570 | 0.0843 | 0.6985 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 655 | 519 | | 12431 | 24620 | 390.0 | 70.08 | 73.02 | 145.52 | 287 | 322 | 350 | 376 | 398 | 418 | 437 | 454 | 476 | 0.0531 | 1307 | 0.717 | 116.71 | 35.11 | 3 | 0.0323 | 401 | 0.0014 | 13.24 | 6.814 | 0.3028 | 157023.0 | 65000000 | 27500000000 | 11900000000000 | 0.4378 | 0.1981 | 0.0007 | 0.0000 | 0.0029 | 0.0000 | 0.0055 | 0.0000 | 0.0115 | 0.0009 | 0.0276 | 0.0098 | 0.0447 | 0.0175 | 0.0492 | 0.0111 | 0.0732 | 0.0171 | 0.7847 | 0.9436 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0000 | 0.0037 | 0.0009 | 0.0122 | 0.0098 | 0.0195 | 0.0175 | 0.0178 | 0.0105 | 0.0271 | 0.0152 | 0.9168 | 0.9461 | 0.0102 | 1.0000 | 0.0215 | 0.0000 | 0.0269 | 0.0000 | 0.0449 | 0.0000 | 0.0682 | 0.0000 | 0.0922 | 0.0000 | 0.0999 | 0.0000 | 0.1191 | 0.0000 | 0.5171 | 0.0000 | 0.0007 | 0.0036 | 0.0042 | 0.0104 | 0.0227 | 0.0348 | 0.0407 | 0.0547 | 0.8282 | 8 | 10 | 11 | 13 | 15 | 20 | 33 | 82 | 218 | 0.1379 | 2.58 | 2.741 | 0.6004 | 26508.4 | 16200000 | 12600000000 | 11400000000000 | 0.6289 | 0.0769 | 0.0413 | 0.0027 | 0.1013 | 0.0182 | 0.1888 | 0.0633 | 0.1750 | 0.0919 | 0.1721 | 0.1461 | 0.1327 | 0.1875 | 0.1013 | 0.1379 | 0.0560 | 0.1347 | 0.0315 | 0.2176 | 0.0002 | 0.0005 | 0.0007 | 0.0006 | 0.0016 | 0.0015 | 0.0123 | 0.0101 | 0.0446 | 0.0428 | 0.0768 | 0.0683 | 0.0519 | 0.0466 | 0.0718 | 0.0703 | 0.7402 | 0.7592 | 0.0004 | 0.0009 | 0.0008 | 0.0018 | 0.0023 | 0.0018 | 0.0159 | 0.0140 | 0.0529 | 0.0605 | 0.0898 | 0.0918 | 0.0567 | 0.0628 | 0.0814 | 0.0868 | 0.6997 | 0.6794 | 0.0004 | 0.0000 | 0.0015 | 0.0114 | 0.0529 | 0.0806 | 0.0550 | 0.0825 | 0.7157 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 810 | 326 | | 3594 | 12663 | 229.7 | 56.19 | 81.87 | 95.54 | 166 | 186 | 198 | 210 | 222 | 234 | 248 | 268 | 303 | 0.0682 | 864 | 1.030 | 171.21 | 41.76 | 1 | 0.1060 | 381 | 0.0016 | 32.05 | 6.715 | 0.2107 | 55902.4 | 14500000 | 4010000000 | 1190000000000 | 0.5035 | 0.1704 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0073 | 0.0012 | 0.0264 | 0.0054 | 0.0878 | 0.0239 | 0.1665 | 0.0760 | 0.1371 | 0.0611 | 0.1600 | 0.0899 | 0.4133 | 0.7424 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0006 | 0.0112 | 0.0031 | 0.0460 | 0.0184 | 0.0978 | 0.0535 | 0.0678 | 0.0337 | 0.0995 | 0.0538 | 0.6753 | 0.8370 | 0.0016 | 0.0131 | 0.0080 | 0.0218 | 0.0080 | 0.0306 | 0.0563 | 0.0961 | 0.1286 | 0.1747 | 0.1785 | 0.1790 | 0.1125 | 0.1004 | 0.1592 | 0.1048 | 0.3473 | 0.2795 | 0.0026 | 0.0045 | 0.0161 | 0.0407 | 0.0956 | 0.1305 | 0.0988 | 0.1292 | 0.4819 | 8 | 10 | 15 | 23 | 40 | 68 | 102 | 146 | 214 | 0.0700 | 5.97 | 4.296 | 0.5831 | 15830.0 | 4370000 | 1490000000 | 589000000000 | 0.5370 | 0.1417 | 0.0369 | 0.0017 | 0.1133 | 0.0166 | 0.1952 | 0.0706 | 0.1622 | 0.1025 | 0.1663 | 0.1515 | 0.1382 | 0.1893 | 0.0916 | 0.1295 | 0.0618 | 0.1295 | 0.0345 | 0.2088 | 0.0008 | 0.0002 | 0.0002 | 0.0007 | 0.0019 | 0.0021 | 0.0124 | 0.0091 | 0.0415 | 0.0341 | 0.0788 | 0.0600 | 0.0633 | 0.0464 | 0.0852 | 0.0678 | 0.7159 | 0.7797 | 0.0013 | 0.0006 | 0.0010 | 0.0015 | 0.0015 | 0.0067 | 0.0194 | 0.0236 | 0.0704 | 0.0744 | 0.1039 | 0.1254 | 0.0801 | 0.0828 | 0.1100 | 0.1108 | 0.6124 | 0.5742 | 0.0000 | 0.0013 | 0.0020 | 0.0132 | 0.0542 | 0.1022 | 0.0678 | 0.0910 | 0.6682 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 961 | 737 | | 4967 | 9103 | 329.4 | 79.77 | 74.56 | 85.94 | 235 | 262 | 283 | 302 | 321 | 340 | 364 | 392 | 439 | 0.0955 | 869 | 1.203 | 114.14 | 50.48 | 1 | 0.0632 | 314 | 0.0010 | 41.76 | 7.101 | 0.1685 | 114878.0 | 42400000 | 16500000000 | 6770000000000 | 0.4275 | 0.2253 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0080 | 0.0002 | 0.0251 | 0.0024 | 0.0931 | 0.0218 | 0.1507 | 0.0517 | 0.1563 | 0.0579 | 0.1845 | 0.0764 | 0.3813 | 0.7896 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0000 | 0.0076 | 0.0006 | 0.0416 | 0.0124 | 0.0718 | 0.0304 | 0.0680 | 0.0240 | 0.1070 | 0.0391 | 0.7025 | 0.8934 | 0.0052 | 0.0061 | 0.0000 | 0.0122 | 0.0241 | 0.0396 | 0.0680 | 0.1250 | 0.1339 | 0.1860 | 0.1695 | 0.1799 | 0.1056 | 0.1128 | 0.1538 | 0.1463 | 0.3400 | 0.1921 | 0.0013 | 0.0013 | 0.0083 | 0.0420 | 0.0918 | 0.1263 | 0.0997 | 0.1228 | 0.5066 | 6 | 8 | 13 | 22 | 41 | 63 | 93 | 132 | 194 | 0.0625 | 5.33 | 4.498 | 0.5801 | 12944.9 | 3140000 | 911000000 | 296000000000 | 0.5225 | 0.1439 | 0.0229 | 0.0000 | 0.1064 | 0.0109 | 0.2273 | 0.0510 | 0.1804 | 0.1108 | 0.1752 | 0.1639 | 0.1470 | 0.1821 | 0.0792 | 0.1561 | 0.0396 | 0.1452 | 0.0219 | 0.1800 | 0.0000 | 0.0000 | 0.0005 | 0.0016 | 0.0008 | 0.0023 | 0.0124 | 0.0105 | 0.0463 | 0.0407 | 0.0816 | 0.0537 | 0.0624 | 0.0553 | 0.0945 | 0.0834 | 0.7015 | 0.7524 | 0.0000 | 0.0008 | 0.0014 | 0.0020 | 0.0056 | 0.0061 | 0.0190 | 0.0228 | 0.0669 | 0.0759 | 0.1025 | 0.1113 | 0.0817 | 0.0893 | 0.1141 | 0.1199 | 0.6088 | 0.5718 | 0.0009 | 0.0006 | 0.0019 | 0.0126 | 0.0638 | 0.0854 | 0.0780 | 0.1043 | 0.6524 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 715 | 284 | | 4349 | 24088 | 89.5 | 13.78 | 5.43 | 2.07 | 73 | 77 | 80 | 84 | 87 | 91 | 97 | 103 | 109 | 0.0418 | 1008 | 0.588 | 324.65 | 84.85 | 1 | 0.2175 | 946 | 0.0394 | 0.86 | 3.496 | 0.6959 | 8200.8 | 769285 | 73900000 | 7250000000 | 0.4494 | 0.2031 | 0.0008 | 0.0000 | 0.0051 | 0.0000 | 0.0102 | 0.0007 | 0.0254 | 0.0044 | 0.0392 | 0.0120 | 0.0621 | 0.0294 | 0.0708 | 0.0204 | 0.1033 | 0.0328 | 0.6830 | 0.9003 | 0.0005 | 0.0000 | 0.0027 | 0.0000 | 0.0056 | 0.0007 | 0.0144 | 0.0037 | 0.0237 | 0.0115 | 0.0345 | 0.0283 | 0.0362 | 0.0170 | 0.0511 | 0.0255 | 0.8312 | 0.9133 | 0.0183 | 0.0800 | 0.0220 | 0.0800 | 0.0661 | 0.0000 | 0.0771 | 0.2400 | 0.0789 | 0.1600 | 0.0881 | 0.0400 | 0.0844 | 0.2800 | 0.1101 | 0.0400 | 0.4550 | 0.0800 | 0.0079 | 0.0173 | 0.0283 | 0.0336 | 0.0378 | 0.0420 | 0.0535 | 0.0991 | 0.6807 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.5147 | 0.30 | 0.895 | 0.8351 | 33.8 | 231.792 | 1719.99 | 13657.8 | 0.5085 | 0.1610 | 0.0301 | 0.0016 | 0.0914 | 0.0107 | 0.1790 | 0.0368 | 0.2367 | 0.0927 | 0.2312 | 0.1792 | 0.1506 | 0.2518 | 0.0667 | 0.2459 | 0.0126 | 0.1425 | 0.0017 | 0.0387 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0019 | 0.0004 | 0.0124 | 0.0041 | 0.0401 | 0.0133 | 0.1042 | 0.0327 | 0.2310 | 0.0785 | 0.3474 | 0.2650 | 0.2627 | 0.6059 | 0.0142 | 0.0719 | 0.0704 | 0.1807 | 0.1551 | 0.2535 | 0.2061 | 0.2209 | 0.2091 | 0.1486 | 0.1568 | 0.0748 | 0.1088 | 0.0355 | 0.0596 | 0.0115 | 0.0198 | 0.0026 | 0.0004 | 0.0054 | 0.0302 | 0.0848 | 0.1735 | 0.2508 | 0.2509 | 0.1550 | 0.0492 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1028 | 672 | | 465 | 2154 | 115.4 | 21.95 | 94.06 | 88.63 | 88 | 97 | 102 | 107 | 113 | 119 | 127 | 135 | 145 | 0.1467 | 316 | 0.423 | 90.70 | 21.40 | 1 | 0.5978 | 278 | 0.0052 | 16.34 | 5.463 | 0.2803 | 13796.9 | 1710000 | 218000000 | 28800000000 | 0.4162 | 0.2196 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0247 | 0.0022 | 0.0556 | 0.0111 | 0.1049 | 0.0509 | 0.1852 | 0.0907 | 0.1420 | 0.0575 | 0.1821 | 0.1062 | 0.3025 | 0.6814 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0022 | 0.0273 | 0.0086 | 0.0695 | 0.0452 | 0.1042 | 0.0839 | 0.0720 | 0.0344 | 0.1117 | 0.0796 | 0.6104 | 0.7462 | 0.0000 | 0.0000 | 0.0380 | 0.1538 | 0.0380 | 0.0000 | 0.1139 | 0.1538 | 0.1519 | 0.3846 | 0.2152 | 0.0000 | 0.1392 | 0.1538 | 0.1139 | 0.1538 | 0.1899 | 0.0000 | 0.0000 | 0.0045 | 0.0179 | 0.0538 | 0.1345 | 0.1211 | 0.1211 | 0.1704 | 0.3767 | 17 | 26 | 35 | 44 | 58 | 78 | 107 | 164 | 229 | 0.0192 | 12.21 | 4.935 | 0.4816 | 16699.0 | 4090000 | 1190000000 | 384000000000 | 0.5433 | 0.1288 | 0.0185 | 0.0036 | 0.1218 | 0.0145 | 0.1808 | 0.0416 | 0.1734 | 0.1139 | 0.2251 | 0.1953 | 0.0959 | 0.1664 | 0.0812 | 0.1356 | 0.0554 | 0.1447 | 0.0480 | 0.1844 | 0.0000 | 0.0000 | 0.0056 | 0.0009 | 0.0090 | 0.0027 | 0.0124 | 0.0192 | 0.0710 | 0.0602 | 0.1150 | 0.0794 | 0.0744 | 0.0776 | 0.1488 | 0.1487 | 0.5637 | 0.6113 | 0.0016 | 0.0000 | 0.0032 | 0.0018 | 0.0065 | 0.0147 | 0.0260 | 0.0313 | 0.0666 | 0.0792 | 0.1380 | 0.1455 | 0.0893 | 0.0958 | 0.1347 | 0.1602 | 0.5341 | 0.4715 | 0.0014 | 0.0082 | 0.0109 | 0.0301 | 0.0657 | 0.1012 | 0.0821 | 0.1477 | 0.5527 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 902 | 772 | | 9805 | 18751 | 104.4 | 27.00 | 104.60 | 154.09 | 71 | 82 | 90 | 97 | 104 | 110 | 117 | 126 | 139 | 0.0633 | 1186 | 1.212 | 43.08 | 15.81 | 3 | 0.0114 | 112 | 0.0025 | 16.76 | 6.319 | 0.2683 | 11632.2 | 1370000 | 170000000 | 22000000000 | 0.4240 | 0.2204 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0088 | 0.0007 | 0.0337 | 0.0037 | 0.0934 | 0.0179 | 0.1645 | 0.0465 | 0.1821 | 0.0638 | 0.1963 | 0.0903 | 0.3200 | 0.7770 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0001 | 0.0076 | 0.0017 | 0.0290 | 0.0096 | 0.0611 | 0.0214 | 0.0697 | 0.0191 | 0.0939 | 0.0324 | 0.7359 | 0.9158 | 0.0079 | 0.0174 | 0.0153 | 0.0349 | 0.0227 | 0.0654 | 0.0811 | 0.1497 | 0.1293 | 0.1715 | 0.1688 | 0.2035 | 0.1433 | 0.1206 | 0.1539 | 0.1206 | 0.2777 | 0.1163 | 0.0006 | 0.0026 | 0.0102 | 0.0307 | 0.0718 | 0.1201 | 0.1160 | 0.1498 | 0.4982 | 11 | 13 | 15 | 19 | 27 | 52 | 104 | 180 | 312 | 0.1458 | 19.88 | 4.207 | 0.6121 | 34684.3 | 18400000 | 13400000000 | 12900000000000 | 0.5548 | 0.1144 | 0.1016 | 0.0053 | 0.2744 | 0.0473 | 0.2848 | 0.2020 | 0.1392 | 0.1879 | 0.0992 | 0.2113 | 0.0544 | 0.1673 | 0.0200 | 0.0877 | 0.0168 | 0.0513 | 0.0096 | 0.0400 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0014 | 0.0010 | 0.0124 | 0.0106 | 0.0714 | 0.0584 | 0.1103 | 0.0965 | 0.0716 | 0.0610 | 0.1148 | 0.1027 | 0.6169 | 0.6690 | 0.0000 | 0.0002 | 0.0014 | 0.0022 | 0.0034 | 0.0082 | 0.0241 | 0.0253 | 0.0928 | 0.1033 | 0.1418 | 0.1582 | 0.0932 | 0.1072 | 0.1495 | 0.1476 | 0.4938 | 0.4478 | 0.0004 | 0.0007 | 0.0034 | 0.0164 | 0.0820 | 0.1252 | 0.0852 | 0.1331 | 0.5536 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 786 | 723 | | 4403 | 10505 | 156.8 | 37.21 | 158.32 | 156.07 | 111 | 125 | 136 | 145 | 154 | 163 | 173 | 187 | 207 | 0.0730 | 767 | 1.082 | 105.15 | 39.01 | 1 | 0.0620 | 273 | 0.0017 | 27.23 | 6.665 | 0.2280 | 25980.4 | 4530000 | 831000000 | 159000000000 | 0.4286 | 0.2358 | 0.0007 | 0.0000 | 0.0045 | 0.0003 | 0.0138 | 0.0018 | 0.0302 | 0.0040 | 0.0832 | 0.0260 | 0.1542 | 0.0510 | 0.1486 | 0.0545 | 0.1725 | 0.0808 | 0.3923 | 0.7817 | 0.0000 | 0.0000 | 0.0009 | 0.0002 | 0.0009 | 0.0002 | 0.0068 | 0.0009 | 0.0392 | 0.0176 | 0.0717 | 0.0309 | 0.0697 | 0.0248 | 0.0958 | 0.0405 | 0.7151 | 0.8849 | 0.0024 | 0.0182 | 0.0155 | 0.0146 | 0.0274 | 0.0474 | 0.0764 | 0.1314 | 0.1372 | 0.1788 | 0.2076 | 0.2336 | 0.1313 | 0.0985 | 0.1396 | 0.1314 | 0.2625 | 0.1460 | 0.0024 | 0.0015 | 0.0068 | 0.0336 | 0.0973 | 0.1357 | 0.1051 | 0.1367 | 0.4810 | 15 | 27 | 45 | 75 | 110 | 150 | 199 | 265 | 380 | 0.0051 | 65.67 | 6.760 | 0.3104 | 49420.1 | 21200000 | 11000000000 | 6460000000000 | 0.5076 | 0.1389 | 0.0172 | 0.0010 | 0.0968 | 0.0078 | 0.2177 | 0.0413 | 0.1765 | 0.0889 | 0.1820 | 0.1633 | 0.1360 | 0.1965 | 0.0859 | 0.1508 | 0.0522 | 0.1403 | 0.0357 | 0.2100 | 0.0006 | 0.0000 | 0.0015 | 0.0009 | 0.0038 | 0.0042 | 0.0125 | 0.0116 | 0.0563 | 0.0446 | 0.0987 | 0.0767 | 0.0747 | 0.0616 | 0.1081 | 0.0892 | 0.6439 | 0.7113 | 0.0009 | 0.0015 | 0.0030 | 0.0036 | 0.0093 | 0.0109 | 0.0246 | 0.0318 | 0.0818 | 0.0982 | 0.1325 | 0.1383 | 0.0971 | 0.0985 | 0.1250 | 0.1438 | 0.5259 | 0.4734 | 0.0002 | 0.0017 | 0.0057 | 0.0214 | 0.0664 | 0.1176 | 0.0927 | 0.1161 | 0.5782 | ||
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 787 | 786 | | 14112 | 32367 | 245.5 | 77.16 | 146.77 | 228.26 | 156 | 185 | 205 | 221 | 237 | 254 | 274 | 301 | 345 | 0.0488 | 1581 | 0.669 | 148.12 | 27.73 | 3 | 0.0257 | 363 | 0.0006 | 60.19 | 7.782 | 0.1687 | 66225.0 | 19500000 | 6230000000 | 2150000000000 | 0.4164 | 0.2099 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0068 | 0.0005 | 0.0211 | 0.0043 | 0.0673 | 0.0249 | 0.1414 | 0.0502 | 0.1309 | 0.0527 | 0.1587 | 0.0666 | 0.4724 | 0.8007 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0025 | 0.0003 | 0.0074 | 0.0026 | 0.0218 | 0.0131 | 0.0526 | 0.0251 | 0.0492 | 0.0237 | 0.0741 | 0.0308 | 0.7916 | 0.9043 | 0.0010 | 0.0021 | 0.0033 | 0.0076 | 0.0118 | 0.0125 | 0.0393 | 0.0569 | 0.1035 | 0.1090 | 0.1432 | 0.1444 | 0.0996 | 0.0938 | 0.1288 | 0.1146 | 0.4695 | 0.4590 | 0.0005 | 0.0024 | 0.0074 | 0.0199 | 0.0565 | 0.1073 | 0.0842 | 0.1154 | 0.6063 | 13 | 15 | 17 | 22 | 34 | 66 | 132 | 244 | 448 | 0.0654 | 39.84 | 4.972 | 0.5439 | 73640.4 | 55300000 | 50400000000 | 51700000000000 | 0.5011 | 0.1602 | 0.0623 | 0.0031 | 0.2185 | 0.0242 | 0.2928 | 0.1386 | 0.1538 | 0.1668 | 0.1059 | 0.2014 | 0.0738 | 0.1699 | 0.0455 | 0.1175 | 0.0254 | 0.0808 | 0.0220 | 0.0977 | 0.0000 | 0.0003 | 0.0009 | 0.0002 | 0.0020 | 0.0009 | 0.0125 | 0.0097 | 0.0604 | 0.0529 | 0.0922 | 0.0798 | 0.0683 | 0.0642 | 0.1028 | 0.0895 | 0.6609 | 0.7026 | 0.0001 | 0.0004 | 0.0013 | 0.0019 | 0.0031 | 0.0054 | 0.0184 | 0.0221 | 0.0771 | 0.0786 | 0.1154 | 0.1217 | 0.0827 | 0.0911 | 0.1160 | 0.1245 | 0.5858 | 0.5543 | 0.0004 | 0.0009 | 0.0021 | 0.0159 | 0.0682 | 0.1066 | 0.0762 | 0.1087 | 0.6210 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 730 | 546 | | 7063 | 16463 | 184.9 | 40.76 | 99.35 | 87.89 | 137 | 151 | 161 | 169 | 179 | 190 | 202 | 219 | 240 | 0.0580 | 955 | 0.941 | 64.47 | 21.02 | 1 | 0.0239 | 169 | 0.0014 | 32.05 | 6.883 | 0.2025 | 35864.6 | 7300000 | 1560000000 | 348000000000 | 0.4301 | 0.2260 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0035 | 0.0000 | 0.0175 | 0.0003 | 0.0785 | 0.0161 | 0.1523 | 0.0437 | 0.1574 | 0.0461 | 0.1936 | 0.0763 | 0.3963 | 0.8174 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0067 | 0.0003 | 0.0317 | 0.0110 | 0.0693 | 0.0226 | 0.0664 | 0.0177 | 0.0909 | 0.0300 | 0.7338 | 0.9185 | 0.0054 | 0.0134 | 0.0069 | 0.0214 | 0.0239 | 0.0456 | 0.0677 | 0.1877 | 0.1524 | 0.2091 | 0.1963 | 0.1743 | 0.1301 | 0.1072 | 0.1617 | 0.1099 | 0.2556 | 0.1314 | 0.0009 | 0.0041 | 0.0135 | 0.0340 | 0.0810 | 0.1216 | 0.1141 | 0.1377 | 0.4931 | 13 | 22 | 36 | 53 | 73 | 98 | 131 | 169 | 224 | 0.0086 | 26.48 | 6.137 | 0.3816 | 17595.6 | 4190000 | 1210000000 | 411000000000 | 0.4596 | 0.1971 | 0.0237 | 0.0019 | 0.1194 | 0.0081 | 0.2469 | 0.0504 | 0.1843 | 0.1053 | 0.1708 | 0.1723 | 0.1252 | 0.1953 | 0.0725 | 0.1462 | 0.0367 | 0.1457 | 0.0206 | 0.1747 | 0.0004 | 0.0003 | 0.0021 | 0.0017 | 0.0031 | 0.0027 | 0.0125 | 0.0104 | 0.0556 | 0.0435 | 0.0954 | 0.0686 | 0.0762 | 0.0660 | 0.1107 | 0.0934 | 0.6440 | 0.7133 | 0.0004 | 0.0007 | 0.0015 | 0.0031 | 0.0060 | 0.0094 | 0.0218 | 0.0307 | 0.0828 | 0.1016 | 0.1359 | 0.1542 | 0.1068 | 0.1143 | 0.1359 | 0.1477 | 0.5090 | 0.4384 | 0.0005 | 0.0005 | 0.0038 | 0.0189 | 0.0670 | 0.1146 | 0.0919 | 0.1238 | 0.5791 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 831 | 627 | | 22430 | 35732 | 126.0 | 38.62 | 252.74 | 227.53 | 82 | 95 | 104 | 113 | 121 | 131 | 142 | 157 | 179 | 0.0532 | 1901 | 0.880 | 73.43 | 20.81 | 2 | 0.0089 | 200 | 0.0017 | 21.99 | 6.753 | 0.2609 | 17379.7 | 2600000 | 417000000 | 71800000000 | 0.4412 | 0.2102 | 0.0006 | 0.0001 | 0.0021 | 0.0002 | 0.0088 | 0.0011 | 0.0346 | 0.0052 | 0.1045 | 0.0291 | 0.1823 | 0.0693 | 0.1643 | 0.0693 | 0.1767 | 0.0997 | 0.3261 | 0.7259 | 0.0002 | 0.0001 | 0.0008 | 0.0001 | 0.0022 | 0.0002 | 0.0101 | 0.0018 | 0.0357 | 0.0141 | 0.0709 | 0.0319 | 0.0688 | 0.0258 | 0.0917 | 0.0432 | 0.7197 | 0.8826 | 0.0034 | 0.0054 | 0.0050 | 0.0100 | 0.0140 | 0.0284 | 0.0533 | 0.0888 | 0.0998 | 0.1568 | 0.1659 | 0.2106 | 0.1164 | 0.1172 | 0.1451 | 0.1426 | 0.3972 | 0.2402 | 0.0011 | 0.0034 | 0.0087 | 0.0271 | 0.0720 | 0.1160 | 0.1006 | 0.1196 | 0.5516 | 16 | 33 | 75 | 138 | 204 | 273 | 343 | 432 | 576 | 0.0082 | 55.93 | 6.842 | 0.3237 | 115644.0 | 68100000 | 47400000000 | 37300000000000 | 0.5184 | 0.1555 | 0.0294 | 0.0010 | 0.1132 | 0.0078 | 0.2146 | 0.0613 | 0.1758 | 0.0954 | 0.1640 | 0.1647 | 0.1397 | 0.1993 | 0.0852 | 0.1472 | 0.0476 | 0.1393 | 0.0304 | 0.1840 | 0.0000 | 0.0002 | 0.0006 | 0.0007 | 0.0018 | 0.0015 | 0.0125 | 0.0070 | 0.0472 | 0.0386 | 0.0990 | 0.0797 | 0.0795 | 0.0590 | 0.1063 | 0.0906 | 0.6532 | 0.7227 | 0.0006 | 0.0013 | 0.0027 | 0.0029 | 0.0077 | 0.0109 | 0.0241 | 0.0340 | 0.0806 | 0.1011 | 0.1356 | 0.1539 | 0.1094 | 0.1178 | 0.1359 | 0.1438 | 0.5033 | 0.4344 | 0.0003 | 0.0016 | 0.0049 | 0.0169 | 0.0624 | 0.1189 | 0.0930 | 0.1202 | 0.5819 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1047 | 808 | | 11793 | 29672 | 113.4 | 29.34 | 199.72 | 175.90 | 81 | 89 | 96 | 102 | 108 | 115 | 124 | 135 | 153 | 0.0534 | 1583 | 0.454 | 192.20 | 38.59 | 5 | 0.0484 | 571 | 0.0029 | 15.86 | 6.239 | 0.2893 | 13720.4 | 1780000 | 247000000 | 36900000000 | 0.5494 | 0.1414 | 0.0009 | 0.0000 | 0.0048 | 0.0002 | 0.0148 | 0.0015 | 0.0418 | 0.0067 | 0.0987 | 0.0255 | 0.1564 | 0.0610 | 0.1565 | 0.0585 | 0.1823 | 0.0902 | 0.3439 | 0.7563 | 0.0005 | 0.0000 | 0.0016 | 0.0002 | 0.0052 | 0.0007 | 0.0169 | 0.0038 | 0.0447 | 0.0139 | 0.0787 | 0.0369 | 0.0757 | 0.0239 | 0.1044 | 0.0426 | 0.6722 | 0.8779 | 0.0055 | 0.0043 | 0.0115 | 0.0182 | 0.0243 | 0.0503 | 0.0545 | 0.1146 | 0.1261 | 0.1767 | 0.1530 | 0.1734 | 0.1129 | 0.1199 | 0.1500 | 0.1370 | 0.3622 | 0.2056 | 0.0035 | 0.0069 | 0.0125 | 0.0420 | 0.0881 | 0.1219 | 0.1128 | 0.1261 | 0.4861 | 21 | 40 | 70 | 109 | 156 | 208 | 264 | 334 | 444 | 0.0045 | 62.50 | 7.035 | 0.2736 | 70826.1 | 33200000 | 18700000000 | 12000000000000 | 0.4909 | 0.1748 | 0.0241 | 0.0016 | 0.1156 | 0.0080 | 0.2373 | 0.0460 | 0.1905 | 0.1069 | 0.1697 | 0.1785 | 0.1335 | 0.2098 | 0.0719 | 0.1527 | 0.0399 | 0.1470 | 0.0174 | 0.1495 | 0.0004 | 0.0002 | 0.0009 | 0.0011 | 0.0042 | 0.0023 | 0.0126 | 0.0094 | 0.0581 | 0.0468 | 0.1027 | 0.0856 | 0.0862 | 0.0727 | 0.1139 | 0.0958 | 0.6211 | 0.6861 | 0.0010 | 0.0011 | 0.0048 | 0.0062 | 0.0108 | 0.0147 | 0.0306 | 0.0373 | 0.0810 | 0.0966 | 0.1391 | 0.1521 | 0.1107 | 0.1138 | 0.1321 | 0.1356 | 0.4899 | 0.4427 | 0.0002 | 0.0024 | 0.0061 | 0.0189 | 0.0699 | 0.1259 | 0.0994 | 0.1257 | 0.5515 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1056 | 260 | | 4207 | 15495 | 500.5 | 108.07 | 87.49 | 106.42 | 370 | 405 | 433 | 464 | 493 | 520 | 549 | 587 | 643 | 0.0565 | 876 | 0.989 | 119.87 | 30.61 | 1 | 0.0661 | 278 | 0.0007 | 62.59 | 7.399 | 0.1476 | 262186.0 | 144000000 | 82200000000 | 49100000000000 | 0.4288 | 0.2109 | 0.0004 | 0.0000 | 0.0015 | 0.0000 | 0.0033 | 0.0003 | 0.0164 | 0.0020 | 0.0574 | 0.0191 | 0.1257 | 0.0417 | 0.1374 | 0.0355 | 0.1640 | 0.0528 | 0.4940 | 0.8486 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0015 | 0.0000 | 0.0073 | 0.0012 | 0.0297 | 0.0144 | 0.0559 | 0.0271 | 0.0612 | 0.0163 | 0.0749 | 0.0302 | 0.7681 | 0.9108 | 0.0029 | 0.0000 | 0.0086 | 0.0052 | 0.0187 | 0.0363 | 0.0691 | 0.0777 | 0.1281 | 0.2280 | 0.1727 | 0.1969 | 0.0964 | 0.0829 | 0.1410 | 0.1451 | 0.3626 | 0.2280 | 0.0015 | 0.0035 | 0.0035 | 0.0266 | 0.0693 | 0.1151 | 0.0925 | 0.1231 | 0.5648 | 8 | 11 | 16 | 26 | 43 | 64 | 98 | 150 | 246 | 0.0352 | 15.63 | 5.119 | 0.5277 | 18978.6 | 5860000 | 2150000000 | 885000000000 | 0.5211 | 0.1359 | 0.0214 | 0.0046 | 0.0878 | 0.0160 | 0.1521 | 0.0567 | 0.1383 | 0.0743 | 0.1784 | 0.1350 | 0.1508 | 0.1607 | 0.1196 | 0.1350 | 0.0920 | 0.1405 | 0.0595 | 0.2771 | 0.0007 | 0.0012 | 0.0020 | 0.0016 | 0.0043 | 0.0040 | 0.0126 | 0.0130 | 0.0415 | 0.0366 | 0.0643 | 0.0582 | 0.0519 | 0.0478 | 0.0821 | 0.0687 | 0.7407 | 0.7690 | 0.0005 | 0.0003 | 0.0002 | 0.0013 | 0.0029 | 0.0039 | 0.0170 | 0.0181 | 0.0503 | 0.0629 | 0.0867 | 0.0982 | 0.0697 | 0.0732 | 0.0965 | 0.1166 | 0.6762 | 0.6256 | 0.0004 | 0.0016 | 0.0036 | 0.0126 | 0.0506 | 0.0725 | 0.0620 | 0.0889 | 0.7079 |