High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 341 | 154 | | 3660 | 2741 | 145.1 | 40.32 | 362.39 | 193.78 | 100 | 113 | 122 | 131 | 139 | 148 | 158 | 173 | 199 | 0.1423 | 390 | 0.690 | 91.44 | 18.79 | 1 | 0.0628 | 230 | 0.0017 | 31.24 | 6.666 | 0.2130 | 22685.8 | 3840000 | 708000000 | 142000000000 | 0.4590 | 0.1971 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0099 | 0.0000 | 0.0292 | 0.0034 | 0.0887 | 0.0281 | 0.1651 | 0.0650 | 0.1547 | 0.0625 | 0.1731 | 0.0940 | 0.3774 | 0.7470 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0018 | 0.0000 | 0.0113 | 0.0020 | 0.0389 | 0.0146 | 0.0752 | 0.0346 | 0.0724 | 0.0242 | 0.0947 | 0.0466 | 0.7043 | 0.8781 | 0.0056 | 0.0031 | 0.0042 | 0.0061 | 0.0225 | 0.0429 | 0.0591 | 0.0982 | 0.1224 | 0.1595 | 0.1758 | 0.2178 | 0.1097 | 0.1012 | 0.1280 | 0.1380 | 0.3727 | 0.2331 | 0.0000 | 0.0056 | 0.0175 | 0.0437 | 0.0936 | 0.1392 | 0.1180 | 0.1311 | 0.4513 | 105 | 176 | 244 | 302 | 359 | 408 | 457 | 521 | 616 | 0.0007 | 113.79 | 7.416 | 0.1244 | 168859.0 | 91300000 | 54900000000 | 35900000000000 | 0.5411 | 0.1415 | 0.0040 | 0.0007 | 0.0464 | 0.0056 | 0.1300 | 0.0190 | 0.1950 | 0.0556 | 0.1963 | 0.0999 | 0.1817 | 0.1955 | 0.1300 | 0.1871 | 0.0756 | 0.1906 | 0.0411 | 0.2461 | 0.0000 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0049 | 0.0305 | 0.0148 | 0.0610 | 0.0473 | 0.1103 | 0.0976 | 0.1139 | 0.0867 | 0.1144 | 0.1114 | 0.5610 | 0.6358 | 0.0032 | 0.0082 | 0.0095 | 0.0148 | 0.0242 | 0.0346 | 0.0621 | 0.0824 | 0.1137 | 0.1466 | 0.1505 | 0.1928 | 0.1232 | 0.1285 | 0.1568 | 0.1450 | 0.3568 | 0.2471 | 0.0007 | 0.0015 | 0.0154 | 0.0308 | 0.0968 | 0.1357 | 0.1086 | 0.1519 | 0.4585 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1208 | 205 | | 6928 | 22071 | 341.7 | 78.65 | 108.42 | 121.55 | 242 | 273 | 297 | 318 | 338 | 358 | 381 | 406 | 444 | 0.0464 | 1025 | 0.821 | 127.02 | 32.56 | 1 | 0.0485 | 336 | 0.0010 | 44.29 | 7.174 | 0.1864 | 122938.0 | 46400000 | 18300000000 | 7530000000000 | 0.4442 | 0.2150 | 0.0005 | 0.0000 | 0.0009 | 0.0002 | 0.0054 | 0.0000 | 0.0289 | 0.0006 | 0.0774 | 0.0196 | 0.1548 | 0.0468 | 0.1496 | 0.0486 | 0.1733 | 0.0699 | 0.4092 | 0.8144 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0007 | 0.0000 | 0.0054 | 0.0001 | 0.0331 | 0.0134 | 0.0668 | 0.0319 | 0.0580 | 0.0246 | 0.0875 | 0.0358 | 0.7479 | 0.8940 | 0.0023 | 0.0124 | 0.0062 | 0.0155 | 0.0247 | 0.0310 | 0.0918 | 0.1455 | 0.1550 | 0.2012 | 0.1958 | 0.1827 | 0.1210 | 0.1022 | 0.1365 | 0.1269 | 0.2668 | 0.1827 | 0.0003 | 0.0015 | 0.0063 | 0.0271 | 0.0855 | 0.1353 | 0.1139 | 0.1317 | 0.4984 | 9 | 13 | 22 | 40 | 63 | 94 | 133 | 188 | 275 | 0.0306 | 13.52 | 5.344 | 0.4677 | 26526.8 | 9310000 | 4040000000 | 2020000000000 | 0.4133 | 0.2398 | 0.0339 | 0.0012 | 0.1396 | 0.0060 | 0.2401 | 0.0523 | 0.1953 | 0.1264 | 0.1400 | 0.1867 | 0.1291 | 0.2003 | 0.0747 | 0.1544 | 0.0331 | 0.1250 | 0.0141 | 0.1478 | 0.0006 | 0.0003 | 0.0014 | 0.0015 | 0.0028 | 0.0033 | 0.0161 | 0.0120 | 0.0537 | 0.0500 | 0.0941 | 0.0727 | 0.0729 | 0.0606 | 0.1043 | 0.0889 | 0.6540 | 0.7107 | 0.0007 | 0.0010 | 0.0031 | 0.0019 | 0.0047 | 0.0087 | 0.0232 | 0.0267 | 0.0849 | 0.0952 | 0.1181 | 0.1316 | 0.0860 | 0.0864 | 0.1223 | 0.1332 | 0.5570 | 0.5153 | 0.0002 | 0.0019 | 0.0039 | 0.0193 | 0.0666 | 0.1098 | 0.0796 | 0.1117 | 0.6070 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 662 | 697 | | 5913 | 18261 | 491.0 | 67.94 | 138.35 | 220.58 | 396 | 436 | 462 | 484 | 500 | 513 | 528 | 544 | 572 | 0.0451 | 824 | 1.176 | 94.54 | 34.99 | 1 | 0.0404 | 239 | 0.0021 | 16.68 | 6.549 | 0.2788 | 245703.0 | 125000000 | 64600000000 | 33900000000000 | 0.4193 | 0.2254 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0010 | 0.0000 | 0.0052 | 0.0002 | 0.0206 | 0.0107 | 0.0401 | 0.0231 | 0.0409 | 0.0105 | 0.0497 | 0.0178 | 0.8421 | 0.9378 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0011 | 0.0002 | 0.0140 | 0.0105 | 0.0257 | 0.0222 | 0.0200 | 0.0095 | 0.0276 | 0.0162 | 0.9112 | 0.9414 | 0.0028 | 0.0000 | 0.0142 | 0.1111 | 0.0426 | 0.1111 | 0.0767 | 0.1111 | 0.1392 | 0.4444 | 0.1193 | 0.2222 | 0.1193 | 0.0000 | 0.1591 | 0.0000 | 0.3267 | 0.0000 | 0.0003 | 0.0033 | 0.0069 | 0.0169 | 0.0350 | 0.0555 | 0.0628 | 0.0872 | 0.7320 | 8 | 10 | 12 | 16 | 27 | 52 | 112 | 246 | 464 | 0.1339 | 21.44 | 4.364 | 0.6125 | 67793.0 | 46900000 | 38600000000 | 36000000000000 | 0.3682 | 0.2671 | 0.0646 | 0.0035 | 0.1579 | 0.0234 | 0.2759 | 0.1034 | 0.1692 | 0.1313 | 0.1344 | 0.1895 | 0.0985 | 0.2004 | 0.0595 | 0.1034 | 0.0236 | 0.1193 | 0.0164 | 0.1258 | 0.0004 | 0.0006 | 0.0011 | 0.0015 | 0.0025 | 0.0023 | 0.0114 | 0.0085 | 0.0461 | 0.0447 | 0.0764 | 0.0614 | 0.0517 | 0.0432 | 0.0719 | 0.0705 | 0.7384 | 0.7673 | 0.0011 | 0.0005 | 0.0009 | 0.0007 | 0.0026 | 0.0033 | 0.0168 | 0.0158 | 0.0521 | 0.0575 | 0.0907 | 0.0945 | 0.0618 | 0.0628 | 0.0783 | 0.0833 | 0.6958 | 0.6816 | 0.0006 | 0.0014 | 0.0028 | 0.0152 | 0.0474 | 0.0861 | 0.0548 | 0.0734 | 0.7183 | ||
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 726 | 600 | | 3242 | 14311 | 499.5 | 83.43 | 217.74 | 192.04 | 394 | 426 | 450 | 470 | 493 | 518 | 547 | 576 | 612 | 0.0641 | 917 | 0.675 | 101.83 | 25.18 | 1 | 0.0999 | 324 | 0.0014 | 30.06 | 6.786 | 0.2232 | 256441.0 | 135000000 | 73000000000 | 40400000000000 | 0.4615 | 0.1909 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0029 | 0.0003 | 0.0094 | 0.0019 | 0.0476 | 0.0128 | 0.1034 | 0.0350 | 0.0932 | 0.0172 | 0.1211 | 0.0428 | 0.6215 | 0.8900 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0031 | 0.0015 | 0.0241 | 0.0115 | 0.0544 | 0.0319 | 0.0457 | 0.0124 | 0.0582 | 0.0254 | 0.8139 | 0.9170 | 0.0069 | 0.2000 | 0.0185 | 0.2000 | 0.0254 | 0.1333 | 0.0762 | 0.2667 | 0.1224 | 0.0667 | 0.2517 | 0.1333 | 0.1201 | 0.0000 | 0.1386 | 0.0000 | 0.2402 | 0.0000 | 0.0026 | 0.0013 | 0.0110 | 0.0272 | 0.0725 | 0.1146 | 0.0881 | 0.1075 | 0.5751 | 27 | 59 | 91 | 117 | 149 | 197 | 277 | 373 | 502 | 0.0056 | 39.72 | 6.385 | 0.3525 | 84287.2 | 43400000 | 26300000000 | 17700000000000 | 0.5008 | 0.1648 | 0.0367 | 0.0032 | 0.1371 | 0.0092 | 0.2234 | 0.0566 | 0.1856 | 0.1095 | 0.1607 | 0.1802 | 0.1201 | 0.1909 | 0.0615 | 0.1404 | 0.0434 | 0.1268 | 0.0316 | 0.1831 | 0.0010 | 0.0008 | 0.0021 | 0.0015 | 0.0046 | 0.0040 | 0.0193 | 0.0143 | 0.0618 | 0.0534 | 0.0900 | 0.0837 | 0.0683 | 0.0638 | 0.1015 | 0.0908 | 0.6515 | 0.6878 | 0.0004 | 0.0008 | 0.0007 | 0.0042 | 0.0048 | 0.0124 | 0.0253 | 0.0287 | 0.0830 | 0.0944 | 0.1247 | 0.1404 | 0.1000 | 0.1138 | 0.1419 | 0.1548 | 0.5192 | 0.4506 | 0.0006 | 0.0023 | 0.0015 | 0.0250 | 0.0581 | 0.1139 | 0.0806 | 0.1154 | 0.6027 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 571 | 922 | | 4617 | 8322 | 491.0 | 95.75 | 198.40 | 274.48 | 372 | 405 | 431 | 459 | 485 | 511 | 541 | 573 | 621 | 0.0908 | 756 | 1.217 | 121.30 | 48.70 | 1 | 0.0682 | 315 | 0.0006 | 68.44 | 7.576 | 0.1426 | 250279.0 | 132000000 | 72100000000 | 40600000000000 | 0.4178 | 0.2313 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0002 | 0.0112 | 0.0025 | 0.0586 | 0.0169 | 0.1189 | 0.0373 | 0.1287 | 0.0263 | 0.1587 | 0.0443 | 0.5217 | 0.8725 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0064 | 0.0011 | 0.0309 | 0.0133 | 0.0554 | 0.0279 | 0.0492 | 0.0168 | 0.0717 | 0.0251 | 0.7855 | 0.9157 | 0.0040 | 0.0000 | 0.0081 | 0.0000 | 0.0256 | 0.0000 | 0.0823 | 0.0000 | 0.1107 | 0.0000 | 0.1741 | 0.0000 | 0.1039 | 0.0000 | 0.1323 | 0.0000 | 0.3590 | 0.0000 | 0.0005 | 0.0023 | 0.0059 | 0.0244 | 0.0765 | 0.1199 | 0.0851 | 0.1231 | 0.5624 | 15 | 20 | 25 | 38 | 68 | 118 | 188 | 348 | 633 | 0.0340 | 31.16 | 5.359 | 0.5201 | 114691.0 | 92700000 | 87100000000 | 90400000000000 | 0.3987 | 0.2243 | 0.0214 | 0.0007 | 0.1193 | 0.0152 | 0.2370 | 0.0550 | 0.1330 | 0.0774 | 0.1361 | 0.1527 | 0.1055 | 0.2069 | 0.0826 | 0.1122 | 0.0841 | 0.1165 | 0.0810 | 0.2634 | 0.0004 | 0.0003 | 0.0029 | 0.0015 | 0.0022 | 0.0021 | 0.0122 | 0.0114 | 0.0561 | 0.0418 | 0.0820 | 0.0749 | 0.0557 | 0.0523 | 0.0805 | 0.0737 | 0.7080 | 0.7419 | 0.0005 | 0.0000 | 0.0014 | 0.0010 | 0.0056 | 0.0031 | 0.0118 | 0.0118 | 0.0592 | 0.0536 | 0.0870 | 0.1050 | 0.0602 | 0.0551 | 0.0827 | 0.0881 | 0.6916 | 0.6823 | 0.0008 | 0.0017 | 0.0033 | 0.0124 | 0.0541 | 0.0880 | 0.0570 | 0.0843 | 0.6985 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 431 | 339 | | 3943 | 10483 | 650.4 | 93.20 | 77.12 | 134.86 | 524 | 578 | 611 | 637 | 655 | 676 | 697 | 725 | 765 | 0.0630 | 660 | 1.066 | 99.30 | 32.65 | 1 | 0.0621 | 245 | 0.0013 | 29.21 | 6.926 | 0.2389 | 431670.0 | 292000000 | 201000000000 | 140000000000000 | 0.4337 | 0.2092 | 0.0006 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0043 | 0.0003 | 0.0239 | 0.0147 | 0.0347 | 0.0234 | 0.0340 | 0.0127 | 0.0534 | 0.0226 | 0.8476 | 0.9264 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0003 | 0.0148 | 0.0147 | 0.0235 | 0.0234 | 0.0179 | 0.0127 | 0.0277 | 0.0226 | 0.9140 | 0.9264 | 0.0065 | 0.0000 | 0.0065 | 0.0000 | 0.0226 | 0.0000 | 0.0355 | 0.0000 | 0.1000 | 0.0000 | 0.0871 | 0.0000 | 0.1065 | 0.0000 | 0.1290 | 0.0000 | 0.5065 | 0.0000 | 0.0000 | 0.0038 | 0.0072 | 0.0191 | 0.0401 | 0.0558 | 0.0615 | 0.0873 | 0.7252 | 6 | 8 | 9 | 11 | 14 | 22 | 53 | 125 | 238 | 0.1380 | 10.00 | 3.574 | 0.6077 | 24132.5 | 11700000 | 7110000000 | 4930000000000 | 0.4308 | 0.2239 | 0.0546 | 0.0060 | 0.1513 | 0.0313 | 0.2122 | 0.0625 | 0.1912 | 0.1159 | 0.1639 | 0.1915 | 0.1261 | 0.1935 | 0.0630 | 0.1381 | 0.0315 | 0.1190 | 0.0063 | 0.1421 | 0.0010 | 0.0000 | 0.0017 | 0.0015 | 0.0024 | 0.0033 | 0.0102 | 0.0118 | 0.0453 | 0.0386 | 0.0572 | 0.0477 | 0.0437 | 0.0443 | 0.0670 | 0.0641 | 0.7716 | 0.7887 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0020 | 0.0017 | 0.0113 | 0.0139 | 0.0577 | 0.0582 | 0.0658 | 0.0747 | 0.0516 | 0.0595 | 0.0791 | 0.0860 | 0.7313 | 0.7059 | 0.0004 | 0.0000 | 0.0015 | 0.0127 | 0.0470 | 0.0601 | 0.0548 | 0.0660 | 0.7576 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1243 | 854 | | 722 | 7966 | 63.7 | 17.26 | 99.18 | 192.37 | 47 | 51 | 53 | 56 | 60 | 63 | 68 | 74 | 85 | 0.0734 | 585 | 0.421 | 183.11 | 37.80 | 0 | 0.8726 | 630 | 0.0093 | 10.56 | 5.018 | 0.3434 | 4360.7 | 324711 | 26600000 | 2420000000 | 0.4665 | 0.1732 | 0.0048 | 0.0000 | 0.0238 | 0.0000 | 0.0499 | 0.0060 | 0.0950 | 0.0255 | 0.1354 | 0.0510 | 0.1853 | 0.0990 | 0.1663 | 0.1049 | 0.1663 | 0.1094 | 0.1734 | 0.6042 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0128 | 0.0028 | 0.0475 | 0.0097 | 0.0786 | 0.0444 | 0.1408 | 0.0819 | 0.1261 | 0.0611 | 0.1481 | 0.0833 | 0.4388 | 0.7167 | 0.0000 | 0.0000 | 0.0317 | 0.0377 | 0.0159 | 0.0755 | 0.0952 | 0.0755 | 0.1825 | 0.3019 | 0.1825 | 0.1321 | 0.1508 | 0.0566 | 0.1508 | 0.2075 | 0.1905 | 0.1132 | 0.0036 | 0.0180 | 0.0288 | 0.0791 | 0.1259 | 0.1691 | 0.1295 | 0.1511 | 0.2950 | 10 | 12 | 14 | 15 | 17 | 19 | 31 | 113 | 371 | 0.1151 | 73.14 | 4.084 | 0.5429 | 46837.2 | 32700000 | 27500000000 | 26300000000000 | 0.6007 | 0.1115 | 0.2664 | 0.0211 | 0.4953 | 0.1607 | 0.2103 | 0.5011 | 0.0280 | 0.1882 | 0.0000 | 0.0782 | 0.0000 | 0.0338 | 0.0000 | 0.0127 | 0.0000 | 0.0042 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0022 | 0.0015 | 0.0056 | 0.0036 | 0.0185 | 0.0247 | 0.0888 | 0.0781 | 0.1355 | 0.1183 | 0.0748 | 0.0848 | 0.1231 | 0.1177 | 0.5509 | 0.5707 | 0.0006 | 0.0007 | 0.0013 | 0.0041 | 0.0083 | 0.0082 | 0.0230 | 0.0211 | 0.0856 | 0.0958 | 0.1540 | 0.1501 | 0.0818 | 0.0795 | 0.1176 | 0.1291 | 0.5278 | 0.5115 | 0.0012 | 0.0024 | 0.0054 | 0.0198 | 0.0929 | 0.1360 | 0.0827 | 0.1210 | 0.5386 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 208 | 697 | | 4527 | 6306 | 102.3 | 37.27 | 112.28 | 143.75 | 55 | 71 | 81 | 90 | 99 | 108 | 118 | 131 | 151 | 0.0815 | 514 | 0.356 | 141.55 | 33.02 | 1 | 0.1199 | 543 | 0.0021 | 18.08 | 6.438 | 0.2850 | 11862.3 | 1530000 | 217000000 | 33600000000 | 0.4631 | 0.1918 | 0.0025 | 0.0009 | 0.0066 | 0.0006 | 0.0244 | 0.0036 | 0.0533 | 0.0097 | 0.1102 | 0.0425 | 0.1554 | 0.0857 | 0.1640 | 0.0808 | 0.1971 | 0.1227 | 0.2864 | 0.6534 | 0.0000 | 0.0005 | 0.0003 | 0.0003 | 0.0054 | 0.0021 | 0.0123 | 0.0049 | 0.0377 | 0.0210 | 0.0595 | 0.0395 | 0.0687 | 0.0333 | 0.1013 | 0.0546 | 0.7149 | 0.8438 | 0.0025 | 0.0115 | 0.0025 | 0.0263 | 0.0193 | 0.0197 | 0.0495 | 0.0609 | 0.1050 | 0.1184 | 0.1310 | 0.1760 | 0.1125 | 0.1250 | 0.1453 | 0.1612 | 0.4324 | 0.3010 | 0.0009 | 0.0033 | 0.0127 | 0.0216 | 0.0701 | 0.1040 | 0.0861 | 0.1092 | 0.5920 | 15 | 19 | 25 | 33 | 49 | 75 | 115 | 180 | 306 | 0.0287 | 20.58 | 5.086 | 0.4862 | 33266.2 | 15000000 | 8150000000 | 4970000000000 | 0.6440 | 0.0881 | 0.0377 | 0.0048 | 0.1319 | 0.0168 | 0.1852 | 0.0743 | 0.1397 | 0.1086 | 0.1570 | 0.1829 | 0.1287 | 0.1589 | 0.0958 | 0.1238 | 0.0628 | 0.1286 | 0.0612 | 0.2013 | 0.0013 | 0.0007 | 0.0027 | 0.0015 | 0.0080 | 0.0067 | 0.0212 | 0.0176 | 0.0734 | 0.0639 | 0.1008 | 0.1002 | 0.0787 | 0.0740 | 0.1084 | 0.1073 | 0.6055 | 0.6279 | 0.0018 | 0.0028 | 0.0025 | 0.0035 | 0.0135 | 0.0063 | 0.0308 | 0.0232 | 0.0776 | 0.0752 | 0.1145 | 0.1308 | 0.0844 | 0.0893 | 0.1041 | 0.1069 | 0.5708 | 0.5619 | 0.0016 | 0.0057 | 0.0109 | 0.0274 | 0.0677 | 0.1117 | 0.0858 | 0.1101 | 0.5791 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 688 | 324 | | 13758 | 21485 | 122.6 | 40.36 | 202.58 | 231.30 | 76 | 90 | 98 | 107 | 117 | 128 | 141 | 156 | 178 | 0.0872 | 1874 | 0.692 | 86.83 | 17.09 | 4 | 0.0151 | 208 | 0.0009 | 37.58 | 7.369 | 0.2047 | 16661.6 | 2480000 | 400000000 | 69100000000 | 0.4692 | 0.2051 | 0.0024 | 0.0004 | 0.0062 | 0.0006 | 0.0139 | 0.0027 | 0.0405 | 0.0084 | 0.0991 | 0.0326 | 0.1598 | 0.0715 | 0.1633 | 0.0626 | 0.1771 | 0.0877 | 0.3378 | 0.7336 | 0.0011 | 0.0002 | 0.0029 | 0.0003 | 0.0047 | 0.0010 | 0.0145 | 0.0048 | 0.0370 | 0.0172 | 0.0555 | 0.0390 | 0.0585 | 0.0291 | 0.0729 | 0.0411 | 0.7528 | 0.8673 | 0.0020 | 0.0037 | 0.0072 | 0.0067 | 0.0133 | 0.0209 | 0.0372 | 0.0491 | 0.0847 | 0.1098 | 0.1175 | 0.1589 | 0.0893 | 0.1141 | 0.1233 | 0.1387 | 0.5255 | 0.3982 | 0.0010 | 0.0026 | 0.0073 | 0.0221 | 0.0578 | 0.0893 | 0.0766 | 0.1021 | 0.6413 | 15 | 20 | 31 | 57 | 109 | 182 | 259 | 358 | 545 | 0.0237 | 41.98 | 5.971 | 0.4277 | 94535.6 | 60700000 | 46900000000 | 41300000000000 | 0.5071 | 0.1526 | 0.0324 | 0.0022 | 0.1222 | 0.0156 | 0.1953 | 0.0725 | 0.1804 | 0.1085 | 0.1681 | 0.1619 | 0.1340 | 0.1825 | 0.0858 | 0.1314 | 0.0495 | 0.1367 | 0.0324 | 0.1888 | 0.0001 | 0.0005 | 0.0017 | 0.0015 | 0.0035 | 0.0027 | 0.0122 | 0.0106 | 0.0577 | 0.0494 | 0.0901 | 0.0778 | 0.0671 | 0.0552 | 0.0932 | 0.0791 | 0.6743 | 0.7233 | 0.0003 | 0.0010 | 0.0028 | 0.0034 | 0.0068 | 0.0100 | 0.0237 | 0.0359 | 0.0811 | 0.0934 | 0.1246 | 0.1344 | 0.0910 | 0.0879 | 0.1214 | 0.1091 | 0.5482 | 0.5250 | 0.0005 | 0.0019 | 0.0048 | 0.0175 | 0.0673 | 0.1061 | 0.0788 | 0.1115 | 0.6117 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 387 | 433 | | 5231 | 10050 | 128.6 | 29.95 | 253.02 | 164.61 | 95 | 106 | 112 | 118 | 124 | 131 | 139 | 149 | 167 | 0.0766 | 770 | 1.025 | 94.58 | 21.95 | 1 | 0.0417 | 218 | 0.0027 | 19.06 | 6.270 | 0.2625 | 17434.3 | 2500000 | 381000000 | 61800000000 | 0.4642 | 0.1924 | 0.0009 | 0.0000 | 0.0012 | 0.0004 | 0.0063 | 0.0008 | 0.0155 | 0.0006 | 0.0748 | 0.0204 | 0.1327 | 0.0433 | 0.1376 | 0.0474 | 0.1804 | 0.0775 | 0.4506 | 0.8094 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0004 | 0.0058 | 0.0004 | 0.0353 | 0.0138 | 0.0679 | 0.0272 | 0.0616 | 0.0216 | 0.0981 | 0.0325 | 0.7281 | 0.9042 | 0.0035 | 0.0236 | 0.0058 | 0.0505 | 0.0256 | 0.0337 | 0.0816 | 0.0741 | 0.1457 | 0.1886 | 0.1620 | 0.1818 | 0.1550 | 0.0976 | 0.1352 | 0.1515 | 0.2855 | 0.1987 | 0.0022 | 0.0065 | 0.0113 | 0.0427 | 0.0946 | 0.1325 | 0.1176 | 0.1451 | 0.4475 | 60 | 102 | 143 | 183 | 224 | 272 | 324 | 390 | 488 | 0.0010 | 93.19 | 7.522 | 0.1835 | 91109.9 | 40300000 | 20400000000 | 11500000000000 | 0.4846 | 0.1715 | 0.0159 | 0.0002 | 0.0785 | 0.0058 | 0.2247 | 0.0267 | 0.1565 | 0.0755 | 0.1770 | 0.1506 | 0.1499 | 0.1952 | 0.0887 | 0.1576 | 0.0612 | 0.1601 | 0.0476 | 0.2282 | 0.0009 | 0.0000 | 0.0011 | 0.0015 | 0.0050 | 0.0019 | 0.0179 | 0.0119 | 0.0651 | 0.0482 | 0.1005 | 0.0787 | 0.0938 | 0.0705 | 0.1206 | 0.1004 | 0.5951 | 0.6868 | 0.0012 | 0.0036 | 0.0041 | 0.0052 | 0.0106 | 0.0203 | 0.0361 | 0.0584 | 0.0993 | 0.1247 | 0.1704 | 0.1918 | 0.1202 | 0.1275 | 0.1539 | 0.1485 | 0.4042 | 0.3201 | 0.0002 | 0.0034 | 0.0073 | 0.0241 | 0.0768 | 0.1375 | 0.1128 | 0.1355 | 0.5024 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 516 | 891 | | 618 | 739 | 106.8 | 15.78 | 5.93 | 2.23 | 82 | 92 | 99 | 105 | 109 | 114 | 118 | 121 | 125 | 0.3234 | 239 | 1.055 | 76.24 | 24.70 | 1 | 0.3026 | 187 | 0.0261 | 2.24 | 3.925 | 0.5232 | 11645.2 | 1290000 | 146000000 | 16700000000 | 0.3863 | 0.2434 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0199 | 0.0000 | 0.0358 | 0.0405 | 0.0875 | 0.0631 | 0.1093 | 0.0275 | 0.1590 | 0.0469 | 0.5885 | 0.8220 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0188 | 0.0000 | 0.0282 | 0.0405 | 0.0545 | 0.0631 | 0.0545 | 0.0275 | 0.0395 | 0.0469 | 0.8045 | 0.8220 | 0.1034 | 0.0000 | 0.2414 | 0.0000 | 0.2414 | 0.0000 | 0.2414 | 0.0000 | 0.1034 | 0.0000 | 0.0690 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0277 | 0.0360 | 0.0305 | 0.0637 | 0.0665 | 0.1108 | 0.6648 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.5158 | 0.30 | 0.942 | 0.8384 | 40.2 | 298.797 | 2399.87 | 20613.1 | 0.4399 | 0.1643 | 0.0054 | 0.0000 | 0.0863 | 0.0054 | 0.1563 | 0.0342 | 0.3100 | 0.1081 | 0.2022 | 0.1856 | 0.1725 | 0.2270 | 0.0566 | 0.2378 | 0.0108 | 0.1640 | 0.0000 | 0.0378 | 0.0000 | 0.0000 | 0.0186 | 0.0016 | 0.0557 | 0.0188 | 0.1002 | 0.0518 | 0.1670 | 0.1256 | 0.2041 | 0.1680 | 0.2059 | 0.2135 | 0.1837 | 0.2370 | 0.0649 | 0.1837 | 0.1845 | 0.4878 | 0.2917 | 0.2195 | 0.2440 | 0.2195 | 0.2024 | 0.0732 | 0.0476 | 0.0000 | 0.0298 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0213 | 0.0520 | 0.1348 | 0.1442 | 0.1891 | 0.1915 | 0.1277 | 0.1040 | 0.0355 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 954 | 880 | | 1679 | 5441 | 653.6 | 119.11 | 75.62 | 146.47 | 478 | 542 | 591 | 627 | 661 | 696 | 731 | 766 | 800 | 0.0884 | 481 | 0.755 | 132.23 | 36.35 | 1 | 0.2287 | 384 | 0.0009 | 82.04 | 7.094 | 0.1478 | 441315.0 | 307000000 | 218000000000 | 159000000000000 | 0.3946 | 0.2342 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0086 | 0.0018 | 0.0522 | 0.0283 | 0.0779 | 0.0361 | 0.0693 | 0.0307 | 0.1259 | 0.0451 | 0.6652 | 0.8581 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0018 | 0.0313 | 0.0281 | 0.0392 | 0.0329 | 0.0271 | 0.0257 | 0.0499 | 0.0418 | 0.8504 | 0.8698 | 0.0042 | 0.0000 | 0.0169 | 0.0000 | 0.0254 | 0.0000 | 0.0424 | 0.0000 | 0.0890 | 0.0000 | 0.1271 | 0.0000 | 0.1144 | 0.0000 | 0.1271 | 0.0000 | 0.4534 | 0.0000 | 0.0011 | 0.0011 | 0.0034 | 0.0103 | 0.0525 | 0.0627 | 0.0490 | 0.0855 | 0.7343 | 7 | 9 | 11 | 13 | 17 | 28 | 60 | 104 | 173 | 0.0733 | 1.76 | 2.761 | 0.5531 | 27168.4 | 17800000 | 14800000000 | 13800000000000 | 0.4065 | 0.2202 | 0.0128 | 0.0026 | 0.0204 | 0.0102 | 0.0510 | 0.0269 | 0.1301 | 0.0409 | 0.1913 | 0.0882 | 0.2041 | 0.1317 | 0.1735 | 0.1228 | 0.1301 | 0.2008 | 0.0867 | 0.3760 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0018 | 0.0027 | 0.0092 | 0.0070 | 0.0308 | 0.0271 | 0.0450 | 0.0411 | 0.0431 | 0.0319 | 0.0603 | 0.0541 | 0.8097 | 0.8343 | 0.0008 | 0.0009 | 0.0000 | 0.0019 | 0.0049 | 0.0075 | 0.0130 | 0.0160 | 0.0381 | 0.0479 | 0.0657 | 0.0695 | 0.0536 | 0.0638 | 0.0869 | 0.0892 | 0.7370 | 0.7033 | 0.0000 | 0.0063 | 0.0042 | 0.0105 | 0.0359 | 0.0450 | 0.0549 | 0.0703 | 0.7729 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1046 | 281 | | 697 | 6737 | 49.7 | 11.06 | 107.38 | 98.61 | 35 | 40 | 43 | 46 | 49 | 53 | 56 | 60 | 66 | 0.0687 | 463 | 0.653 | 94.02 | 20.03 | 1 | 0.3989 | 278 | 0.0147 | 2.37 | 4.400 | 0.5020 | 2589.0 | 140960 | 7970000 | 466000000 | 0.3646 | 0.2679 | 0.0024 | 0.0000 | 0.0049 | 0.0000 | 0.0147 | 0.0015 | 0.0293 | 0.0122 | 0.0880 | 0.0518 | 0.1174 | 0.0487 | 0.1418 | 0.0700 | 0.2103 | 0.1035 | 0.3912 | 0.7123 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0179 | 0.0088 | 0.0448 | 0.0423 | 0.0448 | 0.0350 | 0.0538 | 0.0482 | 0.0878 | 0.0496 | 0.7437 | 0.8161 | 0.0000 | 0.0714 | 0.0067 | 0.0714 | 0.0537 | 0.1071 | 0.0604 | 0.2143 | 0.0940 | 0.1429 | 0.0872 | 0.1429 | 0.0940 | 0.2500 | 0.1678 | 0.0000 | 0.4362 | 0.0000 | 0.0000 | 0.0087 | 0.0029 | 0.0320 | 0.0552 | 0.0698 | 0.0756 | 0.1105 | 0.6453 | 16 | 26 | 41 | 57 | 78 | 101 | 132 | 173 | 239 | 0.0142 | 10.47 | 5.299 | 0.4760 | 21253.2 | 5970000 | 2090000000 | 847000000000 | 0.5145 | 0.1485 | 0.0252 | 0.0015 | 0.0572 | 0.0053 | 0.1725 | 0.0393 | 0.1812 | 0.0766 | 0.1764 | 0.1392 | 0.1764 | 0.1702 | 0.1066 | 0.1387 | 0.0640 | 0.1528 | 0.0407 | 0.2764 | 0.0006 | 0.0003 | 0.0013 | 0.0016 | 0.0064 | 0.0045 | 0.0186 | 0.0143 | 0.0578 | 0.0428 | 0.0902 | 0.0659 | 0.0876 | 0.0653 | 0.1139 | 0.0900 | 0.6236 | 0.7153 | 0.0010 | 0.0023 | 0.0048 | 0.0053 | 0.0120 | 0.0164 | 0.0307 | 0.0282 | 0.0801 | 0.0921 | 0.1243 | 0.1268 | 0.0998 | 0.1009 | 0.1166 | 0.1291 | 0.5307 | 0.4988 | 0.0004 | 0.0020 | 0.0086 | 0.0207 | 0.0718 | 0.1128 | 0.0910 | 0.1175 | 0.5752 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 343 | 118 | | 16901 | 26398 | 141.3 | 44.30 | 218.23 | 252.21 | 94 | 105 | 114 | 123 | 132 | 143 | 157 | 175 | 204 | 0.0815 | 2151 | 0.681 | 101.95 | 26.17 | 6 | 0.0180 | 304 | 0.0015 | 29.37 | 6.914 | 0.2233 | 21941.5 | 3740000 | 696000000 | 140000000000 | 0.5305 | 0.1501 | 0.0011 | 0.0003 | 0.0048 | 0.0008 | 0.0158 | 0.0020 | 0.0410 | 0.0075 | 0.1072 | 0.0328 | 0.1650 | 0.0728 | 0.1666 | 0.0720 | 0.1890 | 0.1025 | 0.3095 | 0.7093 | 0.0006 | 0.0002 | 0.0026 | 0.0004 | 0.0058 | 0.0011 | 0.0146 | 0.0036 | 0.0408 | 0.0175 | 0.0693 | 0.0366 | 0.0679 | 0.0300 | 0.0954 | 0.0486 | 0.7030 | 0.8620 | 0.0021 | 0.0030 | 0.0070 | 0.0090 | 0.0120 | 0.0200 | 0.0527 | 0.0656 | 0.1020 | 0.1512 | 0.1411 | 0.1773 | 0.1049 | 0.1097 | 0.1331 | 0.1607 | 0.4451 | 0.3035 | 0.0015 | 0.0049 | 0.0131 | 0.0289 | 0.0754 | 0.1125 | 0.0940 | 0.1202 | 0.5495 | 20 | 29 | 48 | 79 | 120 | 175 | 259 | 375 | 570 | 0.0118 | 66.19 | 6.470 | 0.3644 | 111232.0 | 85900000 | 88000000000 | 113000000000000 | 0.5942 | 0.0903 | 0.0589 | 0.0022 | 0.1898 | 0.0187 | 0.2385 | 0.1095 | 0.1625 | 0.1457 | 0.1298 | 0.1893 | 0.1051 | 0.1818 | 0.0549 | 0.1192 | 0.0407 | 0.1100 | 0.0196 | 0.1236 | 0.0006 | 0.0005 | 0.0022 | 0.0016 | 0.0043 | 0.0051 | 0.0185 | 0.0152 | 0.0708 | 0.0630 | 0.1147 | 0.0979 | 0.0818 | 0.0754 | 0.1208 | 0.1064 | 0.5863 | 0.6349 | 0.0003 | 0.0018 | 0.0031 | 0.0043 | 0.0077 | 0.0110 | 0.0323 | 0.0372 | 0.0907 | 0.0969 | 0.1399 | 0.1479 | 0.1021 | 0.1013 | 0.1285 | 0.1341 | 0.4956 | 0.4656 | 0.0010 | 0.0025 | 0.0059 | 0.0245 | 0.0763 | 0.1324 | 0.0895 | 0.1228 | 0.5449 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1056 | 260 | | 4207 | 15495 | 500.5 | 108.07 | 87.49 | 106.42 | 370 | 405 | 433 | 464 | 493 | 520 | 549 | 587 | 643 | 0.0565 | 876 | 0.989 | 119.87 | 30.61 | 1 | 0.0661 | 278 | 0.0007 | 62.59 | 7.399 | 0.1476 | 262186.0 | 144000000 | 82200000000 | 49100000000000 | 0.4288 | 0.2109 | 0.0004 | 0.0000 | 0.0015 | 0.0000 | 0.0033 | 0.0003 | 0.0164 | 0.0020 | 0.0574 | 0.0191 | 0.1257 | 0.0417 | 0.1374 | 0.0355 | 0.1640 | 0.0528 | 0.4940 | 0.8486 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0015 | 0.0000 | 0.0073 | 0.0012 | 0.0297 | 0.0144 | 0.0559 | 0.0271 | 0.0612 | 0.0163 | 0.0749 | 0.0302 | 0.7681 | 0.9108 | 0.0029 | 0.0000 | 0.0086 | 0.0052 | 0.0187 | 0.0363 | 0.0691 | 0.0777 | 0.1281 | 0.2280 | 0.1727 | 0.1969 | 0.0964 | 0.0829 | 0.1410 | 0.1451 | 0.3626 | 0.2280 | 0.0015 | 0.0035 | 0.0035 | 0.0266 | 0.0693 | 0.1151 | 0.0925 | 0.1231 | 0.5648 | 8 | 11 | 16 | 26 | 43 | 64 | 98 | 150 | 246 | 0.0352 | 15.63 | 5.119 | 0.5277 | 18978.6 | 5860000 | 2150000000 | 885000000000 | 0.5211 | 0.1359 | 0.0214 | 0.0046 | 0.0878 | 0.0160 | 0.1521 | 0.0567 | 0.1383 | 0.0743 | 0.1784 | 0.1350 | 0.1508 | 0.1607 | 0.1196 | 0.1350 | 0.0920 | 0.1405 | 0.0595 | 0.2771 | 0.0007 | 0.0012 | 0.0020 | 0.0016 | 0.0043 | 0.0040 | 0.0126 | 0.0130 | 0.0415 | 0.0366 | 0.0643 | 0.0582 | 0.0519 | 0.0478 | 0.0821 | 0.0687 | 0.7407 | 0.7690 | 0.0005 | 0.0003 | 0.0002 | 0.0013 | 0.0029 | 0.0039 | 0.0170 | 0.0181 | 0.0503 | 0.0629 | 0.0867 | 0.0982 | 0.0697 | 0.0732 | 0.0965 | 0.1166 | 0.6762 | 0.6256 | 0.0004 | 0.0016 | 0.0036 | 0.0126 | 0.0506 | 0.0725 | 0.0620 | 0.0889 | 0.7079 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1021 | 289 | | 15480 | 20962 | 107.9 | 32.54 | 126.87 | 115.24 | 70 | 80 | 88 | 96 | 104 | 112 | 122 | 133 | 151 | 0.0665 | 1394 | 1.246 | 41.87 | 18.36 | 4 | 0.0075 | 116 | 0.0011 | 32.98 | 7.115 | 0.2122 | 12708.7 | 1630000 | 225000000 | 33600000000 | 0.4430 | 0.2071 | 0.0021 | 0.0002 | 0.0042 | 0.0005 | 0.0146 | 0.0012 | 0.0424 | 0.0071 | 0.1092 | 0.0273 | 0.1709 | 0.0639 | 0.1595 | 0.0673 | 0.1788 | 0.1076 | 0.3183 | 0.7248 | 0.0014 | 0.0002 | 0.0020 | 0.0003 | 0.0039 | 0.0009 | 0.0118 | 0.0037 | 0.0393 | 0.0149 | 0.0650 | 0.0333 | 0.0601 | 0.0290 | 0.0876 | 0.0504 | 0.7289 | 0.8672 | 0.0025 | 0.0080 | 0.0037 | 0.0173 | 0.0202 | 0.0306 | 0.0567 | 0.0766 | 0.1110 | 0.1671 | 0.1514 | 0.1598 | 0.1194 | 0.1152 | 0.1455 | 0.1418 | 0.3896 | 0.2836 | 0.0011 | 0.0021 | 0.0090 | 0.0274 | 0.0627 | 0.1065 | 0.0944 | 0.1225 | 0.5742 | 16 | 27 | 45 | 67 | 94 | 124 | 161 | 212 | 289 | 0.0159 | 8.96 | 5.332 | 0.5036 | 29376.6 | 9390000 | 3750000000 | 1790000000000 | 0.4948 | 0.1572 | 0.0112 | 0.0016 | 0.0613 | 0.0068 | 0.1433 | 0.0245 | 0.1682 | 0.0618 | 0.1919 | 0.1370 | 0.1645 | 0.1771 | 0.1051 | 0.1416 | 0.0836 | 0.1568 | 0.0709 | 0.2928 | 0.0008 | 0.0004 | 0.0011 | 0.0016 | 0.0035 | 0.0026 | 0.0133 | 0.0076 | 0.0489 | 0.0371 | 0.0788 | 0.0577 | 0.0640 | 0.0520 | 0.0930 | 0.0767 | 0.6966 | 0.7643 | 0.0006 | 0.0013 | 0.0028 | 0.0020 | 0.0070 | 0.0071 | 0.0249 | 0.0329 | 0.0705 | 0.0821 | 0.1139 | 0.1305 | 0.0891 | 0.1028 | 0.1163 | 0.1349 | 0.5748 | 0.5065 | 0.0001 | 0.0018 | 0.0055 | 0.0186 | 0.0602 | 0.0898 | 0.0819 | 0.1099 | 0.6321 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1033 | 712 | | 5129 | 6293 | 97.3 | 21.87 | 101.52 | 63.35 | 73 | 79 | 84 | 89 | 94 | 99 | 105 | 113 | 127 | 0.1198 | 754 | 1.045 | 82.39 | 32.89 | 1 | 0.0454 | 233 | 0.0050 | 8.89 | 5.676 | 0.3565 | 9951.5 | 1070000 | 122000000 | 14600000000 | 0.4238 | 0.2335 | 0.0015 | 0.0002 | 0.0027 | 0.0006 | 0.0094 | 0.0006 | 0.0277 | 0.0027 | 0.0690 | 0.0239 | 0.1298 | 0.0420 | 0.1351 | 0.0409 | 0.1808 | 0.0709 | 0.4441 | 0.8180 | 0.0009 | 0.0000 | 0.0014 | 0.0002 | 0.0042 | 0.0004 | 0.0117 | 0.0006 | 0.0391 | 0.0163 | 0.0615 | 0.0248 | 0.0667 | 0.0163 | 0.1036 | 0.0330 | 0.7109 | 0.9084 | 0.0057 | 0.0123 | 0.0181 | 0.0370 | 0.0294 | 0.0216 | 0.0611 | 0.0957 | 0.1041 | 0.1698 | 0.1561 | 0.1698 | 0.1210 | 0.1327 | 0.1493 | 0.1481 | 0.3552 | 0.2130 | 0.0022 | 0.0075 | 0.0141 | 0.0435 | 0.0804 | 0.1094 | 0.1094 | 0.1313 | 0.5024 | 30 | 47 | 61 | 73 | 88 | 104 | 126 | 153 | 191 | 0.0033 | 26.60 | 6.249 | 0.2945 | 14318.5 | 2510000 | 508000000 | 114000000000 | 0.5313 | 0.1551 | 0.0099 | 0.0024 | 0.0992 | 0.0097 | 0.1686 | 0.0286 | 0.1523 | 0.0721 | 0.1856 | 0.1352 | 0.1664 | 0.1776 | 0.1126 | 0.1579 | 0.0729 | 0.1655 | 0.0326 | 0.2510 | 0.0006 | 0.0002 | 0.0044 | 0.0016 | 0.0050 | 0.0032 | 0.0174 | 0.0114 | 0.0636 | 0.0473 | 0.1271 | 0.0905 | 0.1043 | 0.0864 | 0.1315 | 0.1093 | 0.5460 | 0.6500 | 0.0010 | 0.0014 | 0.0051 | 0.0095 | 0.0112 | 0.0265 | 0.0446 | 0.0522 | 0.1076 | 0.1255 | 0.1862 | 0.2171 | 0.1476 | 0.1452 | 0.1558 | 0.1567 | 0.3409 | 0.2659 | 0.0019 | 0.0023 | 0.0096 | 0.0266 | 0.0914 | 0.1450 | 0.1226 | 0.1546 | 0.4458 | ||
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 961 | 737 | | 4967 | 9103 | 329.4 | 79.77 | 74.56 | 85.94 | 235 | 262 | 283 | 302 | 321 | 340 | 364 | 392 | 439 | 0.0955 | 869 | 1.203 | 114.14 | 50.48 | 1 | 0.0632 | 314 | 0.0010 | 41.76 | 7.101 | 0.1685 | 114878.0 | 42400000 | 16500000000 | 6770000000000 | 0.4275 | 0.2253 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0080 | 0.0002 | 0.0251 | 0.0024 | 0.0931 | 0.0218 | 0.1507 | 0.0517 | 0.1563 | 0.0579 | 0.1845 | 0.0764 | 0.3813 | 0.7896 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0000 | 0.0076 | 0.0006 | 0.0416 | 0.0124 | 0.0718 | 0.0304 | 0.0680 | 0.0240 | 0.1070 | 0.0391 | 0.7025 | 0.8934 | 0.0052 | 0.0061 | 0.0000 | 0.0122 | 0.0241 | 0.0396 | 0.0680 | 0.1250 | 0.1339 | 0.1860 | 0.1695 | 0.1799 | 0.1056 | 0.1128 | 0.1538 | 0.1463 | 0.3400 | 0.1921 | 0.0013 | 0.0013 | 0.0083 | 0.0420 | 0.0918 | 0.1263 | 0.0997 | 0.1228 | 0.5066 | 6 | 8 | 13 | 22 | 41 | 63 | 93 | 132 | 194 | 0.0625 | 5.33 | 4.498 | 0.5801 | 12944.9 | 3140000 | 911000000 | 296000000000 | 0.5225 | 0.1439 | 0.0229 | 0.0000 | 0.1064 | 0.0109 | 0.2273 | 0.0510 | 0.1804 | 0.1108 | 0.1752 | 0.1639 | 0.1470 | 0.1821 | 0.0792 | 0.1561 | 0.0396 | 0.1452 | 0.0219 | 0.1800 | 0.0000 | 0.0000 | 0.0005 | 0.0016 | 0.0008 | 0.0023 | 0.0124 | 0.0105 | 0.0463 | 0.0407 | 0.0816 | 0.0537 | 0.0624 | 0.0553 | 0.0945 | 0.0834 | 0.7015 | 0.7524 | 0.0000 | 0.0008 | 0.0014 | 0.0020 | 0.0056 | 0.0061 | 0.0190 | 0.0228 | 0.0669 | 0.0759 | 0.1025 | 0.1113 | 0.0817 | 0.0893 | 0.1141 | 0.1199 | 0.6088 | 0.5718 | 0.0009 | 0.0006 | 0.0019 | 0.0126 | 0.0638 | 0.0854 | 0.0780 | 0.1043 | 0.6524 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 925 | 483 | | 3069 | 17112 | 133.0 | 40.22 | 103.86 | 203.05 | 76 | 97 | 114 | 125 | 135 | 144 | 156 | 169 | 185 | 0.0464 | 794 | 0.346 | 113.00 | 13.45 | 1 | 0.1036 | 318 | 0.0020 | 15.03 | 6.464 | 0.2683 | 19308.7 | 2990000 | 486000000 | 82200000000 | 0.3770 | 0.2497 | 0.0000 | 0.0000 | 0.0061 | 0.0008 | 0.0067 | 0.0008 | 0.0223 | 0.0066 | 0.0756 | 0.0370 | 0.1201 | 0.0555 | 0.1066 | 0.0588 | 0.1296 | 0.0867 | 0.5331 | 0.7538 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0004 | 0.0004 | 0.0065 | 0.0033 | 0.0230 | 0.0218 | 0.0390 | 0.0336 | 0.0295 | 0.0251 | 0.0464 | 0.0369 | 0.8553 | 0.8783 | 0.0000 | 0.0072 | 0.0036 | 0.0036 | 0.0109 | 0.0324 | 0.0339 | 0.0755 | 0.0593 | 0.1547 | 0.1186 | 0.1007 | 0.1005 | 0.1583 | 0.1223 | 0.1151 | 0.5508 | 0.3525 | 0.0006 | 0.0006 | 0.0031 | 0.0161 | 0.0433 | 0.0644 | 0.0718 | 0.0934 | 0.7067 | 11 | 13 | 16 | 21 | 29 | 46 | 76 | 134 | 243 | 0.0626 | 20.97 | 4.597 | 0.5710 | 52014.4 | 50700000 | 63400000000 | 88800000000000 | 0.5552 | 0.1464 | 0.0385 | 0.0020 | 0.1709 | 0.0137 | 0.2873 | 0.1186 | 0.1533 | 0.1182 | 0.1415 | 0.1703 | 0.1114 | 0.2121 | 0.0427 | 0.1186 | 0.0369 | 0.1014 | 0.0176 | 0.1452 | 0.0004 | 0.0007 | 0.0010 | 0.0017 | 0.0045 | 0.0040 | 0.0170 | 0.0154 | 0.0622 | 0.0508 | 0.1379 | 0.1125 | 0.0614 | 0.0648 | 0.0821 | 0.0786 | 0.6335 | 0.6716 | 0.0014 | 0.0009 | 0.0049 | 0.0060 | 0.0140 | 0.0158 | 0.0198 | 0.0211 | 0.0673 | 0.0687 | 0.1389 | 0.1378 | 0.0579 | 0.0627 | 0.0826 | 0.0880 | 0.6132 | 0.5990 | 0.0005 | 0.0036 | 0.0082 | 0.0192 | 0.0694 | 0.1387 | 0.0634 | 0.0742 | 0.6229 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1026 | 526 | | 1774 | 10377 | 333.7 | 82.77 | 7.07 | 6.95 | 228 | 252 | 275 | 299 | 328 | 356 | 381 | 404 | 456 | 0.0754 | 782 | 1.019 | 63.03 | 17.72 | 1 | 0.0902 | 160 | 0.0074 | 2.20 | 5.116 | 0.5219 | 118176.0 | 44200000 | 17400000000 | 7100000000000 | 0.3704 | 0.2523 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0044 | 0.0018 | 0.0196 | 0.0031 | 0.0480 | 0.0270 | 0.0981 | 0.0590 | 0.0960 | 0.0277 | 0.1156 | 0.0522 | 0.6161 | 0.8291 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0006 | 0.0077 | 0.0006 | 0.0216 | 0.0198 | 0.0448 | 0.0475 | 0.0309 | 0.0158 | 0.0394 | 0.0300 | 0.8533 | 0.8858 | 0.0000 | 0.0070 | 0.0026 | 0.0000 | 0.0159 | 0.0211 | 0.0265 | 0.0493 | 0.0688 | 0.0563 | 0.0688 | 0.0634 | 0.0794 | 0.1197 | 0.0926 | 0.1127 | 0.6455 | 0.5704 | 0.0000 | 0.0012 | 0.0035 | 0.0106 | 0.0307 | 0.0507 | 0.0460 | 0.0507 | 0.8066 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.0683 | 0.36 | 0.960 | 0.2803 | 98.4 | 3645.61 | 211535 | 13700000 | 0.5870 | 0.1077 | 0.0219 | 0.0000 | 0.0918 | 0.0034 | 0.2036 | 0.0218 | 0.2478 | 0.0615 | 0.2315 | 0.1441 | 0.1344 | 0.2346 | 0.0524 | 0.2632 | 0.0151 | 0.1992 | 0.0014 | 0.0723 | 0.0070 | 0.0001 | 0.0372 | 0.0017 | 0.1009 | 0.0115 | 0.1433 | 0.0351 | 0.1866 | 0.1006 | 0.1797 | 0.1701 | 0.1357 | 0.2256 | 0.0991 | 0.2326 | 0.1105 | 0.2226 | 0.2165 | 0.2377 | 0.1957 | 0.1575 | 0.1447 | 0.1137 | 0.0919 | 0.0699 | 0.0705 | 0.0657 | 0.0566 | 0.0428 | 0.0334 | 0.0323 | 0.0340 | 0.0396 | 0.1567 | 0.2409 | 0.0252 | 0.0972 | 0.1538 | 0.1674 | 0.1709 | 0.1299 | 0.1019 | 0.0664 | 0.0874 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1271 | 351 | | 4157 | 9898 | 475.9 | 89.44 | 163.26 | 251.77 | 360 | 394 | 423 | 449 | 475 | 498 | 524 | 554 | 594 | 0.0813 | 805 | 1.028 | 152.20 | 40.79 | 2 | 0.0871 | 362 | 0.0008 | 73.60 | 7.318 | 0.1483 | 234454.0 | 119000000 | 62600000000 | 33700000000000 | 0.4174 | 0.2233 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0017 | 0.0000 | 0.0196 | 0.0010 | 0.0716 | 0.0187 | 0.1191 | 0.0382 | 0.1160 | 0.0296 | 0.1725 | 0.0500 | 0.4981 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0069 | 0.0007 | 0.0343 | 0.0162 | 0.0480 | 0.0300 | 0.0474 | 0.0157 | 0.0809 | 0.0288 | 0.7811 | 0.9086 | 0.0000 | 0.0390 | 0.0204 | 0.0260 | 0.0471 | 0.1429 | 0.0973 | 0.2597 | 0.1476 | 0.2338 | 0.2057 | 0.1558 | 0.1350 | 0.0779 | 0.1162 | 0.0519 | 0.2308 | 0.0130 | 0.0010 | 0.0010 | 0.0048 | 0.0299 | 0.0676 | 0.1356 | 0.1236 | 0.1472 | 0.4894 | 7 | 10 | 13 | 22 | 39 | 75 | 136 | 293 | 547 | 0.0676 | 32.18 | 4.895 | 0.5343 | 90034.8 | 69000000 | 62100000000 | 62700000000000 | 0.5861 | 0.0893 | 0.0409 | 0.0025 | 0.1595 | 0.0187 | 0.2704 | 0.0934 | 0.2179 | 0.1214 | 0.1595 | 0.1766 | 0.0914 | 0.2054 | 0.0311 | 0.1350 | 0.0214 | 0.1180 | 0.0078 | 0.1290 | 0.0003 | 0.0003 | 0.0013 | 0.0017 | 0.0043 | 0.0049 | 0.0140 | 0.0129 | 0.0478 | 0.0466 | 0.0870 | 0.0765 | 0.0558 | 0.0552 | 0.0797 | 0.0797 | 0.7096 | 0.7222 | 0.0004 | 0.0000 | 0.0016 | 0.0017 | 0.0028 | 0.0043 | 0.0172 | 0.0170 | 0.0537 | 0.0679 | 0.1034 | 0.0909 | 0.0577 | 0.0635 | 0.0885 | 0.0905 | 0.6747 | 0.6642 | 0.0000 | 0.0026 | 0.0026 | 0.0125 | 0.0521 | 0.0922 | 0.0558 | 0.0845 | 0.6978 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 232 | 638 | | 6254 | 5949 | 114.7 | 25.41 | 187.62 | 143.24 | 87 | 94 | 100 | 105 | 110 | 116 | 123 | 132 | 150 | 0.1308 | 778 | 0.961 | 106.23 | 31.32 | 1 | 0.0421 | 263 | 0.0034 | 14.14 | 6.046 | 0.2876 | 13792.0 | 1750000 | 233000000 | 32800000000 | 0.4648 | 0.1869 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0092 | 0.0003 | 0.0230 | 0.0024 | 0.0653 | 0.0177 | 0.1219 | 0.0491 | 0.1387 | 0.0346 | 0.1702 | 0.0694 | 0.4696 | 0.8265 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0003 | 0.0324 | 0.0105 | 0.0605 | 0.0277 | 0.0714 | 0.0137 | 0.0961 | 0.0290 | 0.7274 | 0.9189 | 0.0097 | 0.0198 | 0.0117 | 0.0074 | 0.0272 | 0.0272 | 0.0690 | 0.0743 | 0.1370 | 0.2030 | 0.1594 | 0.1807 | 0.1108 | 0.1436 | 0.1429 | 0.1337 | 0.3324 | 0.2104 | 0.0023 | 0.0109 | 0.0214 | 0.0436 | 0.1019 | 0.1320 | 0.1169 | 0.1421 | 0.4289 | 42 | 65 | 88 | 115 | 148 | 183 | 233 | 303 | 394 | 0.0021 | 69.90 | 6.913 | 0.2582 | 55713.5 | 21700000 | 10100000000 | 5300000000000 | 0.5779 | 0.0961 | 0.0346 | 0.0023 | 0.1508 | 0.0121 | 0.2315 | 0.0680 | 0.1585 | 0.1253 | 0.1537 | 0.1524 | 0.1162 | 0.1729 | 0.0836 | 0.1356 | 0.0500 | 0.1212 | 0.0211 | 0.2102 | 0.0017 | 0.0003 | 0.0017 | 0.0017 | 0.0069 | 0.0050 | 0.0247 | 0.0182 | 0.0897 | 0.0636 | 0.1357 | 0.1151 | 0.1103 | 0.0851 | 0.1454 | 0.1258 | 0.4838 | 0.5854 | 0.0016 | 0.0047 | 0.0064 | 0.0034 | 0.0112 | 0.0229 | 0.0508 | 0.0518 | 0.1086 | 0.1312 | 0.1825 | 0.1783 | 0.1215 | 0.1285 | 0.1429 | 0.1406 | 0.3745 | 0.3385 | 0.0004 | 0.0017 | 0.0120 | 0.0322 | 0.1043 | 0.1550 | 0.1245 | 0.1426 | 0.4272 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 854 | 416 | | 11131 | 15417 | 454.3 | 71.88 | 90.38 | 157.98 | 358 | 393 | 418 | 438 | 454 | 468 | 484 | 508 | 549 | 0.0688 | 1061 | 1.159 | 147.22 | 49.48 | 2 | 0.0314 | 350 | 0.0013 | 17.13 | 6.964 | 0.2615 | 211570.0 | 101000000 | 49300000000 | 24600000000000 | 0.4019 | 0.2435 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0025 | 0.0005 | 0.0056 | 0.0007 | 0.0198 | 0.0107 | 0.0364 | 0.0188 | 0.0370 | 0.0124 | 0.0542 | 0.0178 | 0.8429 | 0.9388 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0023 | 0.0002 | 0.0110 | 0.0093 | 0.0213 | 0.0169 | 0.0198 | 0.0089 | 0.0278 | 0.0138 | 0.9153 | 0.9509 | 0.0058 | 0.0159 | 0.0075 | 0.0397 | 0.0100 | 0.0556 | 0.0325 | 0.1270 | 0.0600 | 0.0873 | 0.0783 | 0.1349 | 0.0666 | 0.1111 | 0.0966 | 0.0952 | 0.6428 | 0.3333 | 0.0012 | 0.0023 | 0.0068 | 0.0178 | 0.0371 | 0.0570 | 0.0697 | 0.0892 | 0.7189 | 7 | 9 | 10 | 11 | 14 | 23 | 53 | 139 | 311 | 0.2296 | 12.11 | 3.590 | 0.7091 | 33126.6 | 17600000 | 11100000000 | 7920000000000 | 0.5835 | 0.1060 | 0.0228 | 0.0066 | 0.0791 | 0.0185 | 0.1263 | 0.0524 | 0.1948 | 0.0739 | 0.1933 | 0.1344 | 0.1522 | 0.1839 | 0.0898 | 0.1440 | 0.0883 | 0.1322 | 0.0533 | 0.2541 | 0.0000 | 0.0006 | 0.0012 | 0.0017 | 0.0021 | 0.0039 | 0.0062 | 0.0067 | 0.0321 | 0.0323 | 0.0482 | 0.0424 | 0.0349 | 0.0336 | 0.0634 | 0.0528 | 0.8120 | 0.8259 | 0.0011 | 0.0003 | 0.0031 | 0.0018 | 0.0025 | 0.0028 | 0.0098 | 0.0104 | 0.0419 | 0.0429 | 0.0613 | 0.0726 | 0.0526 | 0.0643 | 0.0793 | 0.0867 | 0.7482 | 0.7182 | 0.0003 | 0.0013 | 0.0028 | 0.0103 | 0.0339 | 0.0573 | 0.0419 | 0.0637 | 0.7885 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1057 | 334 | | 2802 | 7296 | 92.2 | 25.90 | 117.02 | 76.72 | 61 | 72 | 78 | 83 | 89 | 94 | 102 | 114 | 128 | 0.0968 | 706 | 0.875 | 120.79 | 34.99 | 2 | 0.1071 | 300 | 0.0040 | 10.09 | 5.865 | 0.3358 | 9174.8 | 979929 | 112000000 | 13500000000 | 0.4595 | 0.1918 | 0.0026 | 0.0000 | 0.0019 | 0.0000 | 0.0136 | 0.0034 | 0.0285 | 0.0107 | 0.0783 | 0.0390 | 0.1462 | 0.0642 | 0.1481 | 0.0723 | 0.1708 | 0.0985 | 0.4101 | 0.7119 | 0.0005 | 0.0000 | 0.0009 | 0.0000 | 0.0055 | 0.0027 | 0.0110 | 0.0050 | 0.0375 | 0.0249 | 0.0536 | 0.0345 | 0.0659 | 0.0383 | 0.0893 | 0.0509 | 0.7358 | 0.8437 | 0.0031 | 0.0036 | 0.0047 | 0.0182 | 0.0219 | 0.0400 | 0.0470 | 0.0800 | 0.0799 | 0.1091 | 0.1270 | 0.1564 | 0.0831 | 0.1273 | 0.1191 | 0.1309 | 0.5141 | 0.3345 | 0.0057 | 0.0123 | 0.0188 | 0.0286 | 0.0645 | 0.0989 | 0.0784 | 0.1078 | 0.5850 | 35 | 49 | 64 | 82 | 101 | 122 | 146 | 178 | 225 | 0.0071 | 10.21 | 5.520 | 0.4012 | 19579.1 | 4150000 | 1040000000 | 297000000000 | 0.5233 | 0.1494 | 0.0087 | 0.0019 | 0.0570 | 0.0036 | 0.1531 | 0.0185 | 0.1866 | 0.0588 | 0.2102 | 0.1426 | 0.1618 | 0.1929 | 0.1054 | 0.1643 | 0.0688 | 0.1647 | 0.0484 | 0.2527 | 0.0015 | 0.0006 | 0.0028 | 0.0017 | 0.0081 | 0.0062 | 0.0233 | 0.0159 | 0.0535 | 0.0453 | 0.0933 | 0.0805 | 0.0813 | 0.0620 | 0.1102 | 0.0836 | 0.6260 | 0.7042 | 0.0013 | 0.0023 | 0.0047 | 0.0085 | 0.0214 | 0.0194 | 0.0343 | 0.0461 | 0.0909 | 0.1071 | 0.1496 | 0.1720 | 0.1127 | 0.1236 | 0.1444 | 0.1384 | 0.4406 | 0.3827 | 0.0026 | 0.0058 | 0.0125 | 0.0295 | 0.0655 | 0.1210 | 0.1079 | 0.1339 | 0.5213 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 409 | 890 | | 816 | 11183 | 89.7 | 9.29 | 105.45 | 153.75 | 78 | 81 | 84 | 87 | 90 | 92 | 95 | 98 | 101 | 0.0640 | 716 | 0.688 | 118.34 | 30.02 | 4 | 0.4142 | 338 | 0.0250 | 2.26 | 3.936 | 0.5414 | 8132.4 | 745123 | 69000000 | 6450000000 | 0.4240 | 0.2141 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0038 | 0.0012 | 0.0166 | 0.0086 | 0.0422 | 0.0319 | 0.0575 | 0.0564 | 0.0665 | 0.0380 | 0.1151 | 0.0576 | 0.6982 | 0.8064 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0012 | 0.0137 | 0.0086 | 0.0373 | 0.0319 | 0.0460 | 0.0564 | 0.0522 | 0.0380 | 0.0646 | 0.0576 | 0.7826 | 0.8064 | 0.1304 | 0.0000 | 0.0870 | 0.0000 | 0.0870 | 0.0000 | 0.2174 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.0870 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0048 | 0.0096 | 0.0265 | 0.0265 | 0.0964 | 0.1084 | 0.1084 | 0.1880 | 0.4313 | 12 | 15 | 19 | 25 | 36 | 56 | 93 | 175 | 308 | 0.0583 | 19.57 | 4.627 | 0.5749 | 34757.8 | 18600000 | 13100000000 | 11000000000000 | 0.5602 | 0.1268 | 0.0620 | 0.0049 | 0.1860 | 0.0220 | 0.2709 | 0.1170 | 0.1685 | 0.1506 | 0.1119 | 0.1935 | 0.0876 | 0.1911 | 0.0539 | 0.1066 | 0.0270 | 0.0980 | 0.0323 | 0.1164 | 0.0006 | 0.0010 | 0.0025 | 0.0017 | 0.0048 | 0.0048 | 0.0202 | 0.0167 | 0.0663 | 0.0628 | 0.1003 | 0.0944 | 0.0621 | 0.0604 | 0.1056 | 0.0980 | 0.6376 | 0.6603 | 0.0011 | 0.0004 | 0.0011 | 0.0008 | 0.0032 | 0.0054 | 0.0231 | 0.0233 | 0.0774 | 0.0848 | 0.1214 | 0.1431 | 0.0781 | 0.0809 | 0.1256 | 0.1268 | 0.5692 | 0.5344 | 0.0010 | 0.0016 | 0.0058 | 0.0214 | 0.0672 | 0.1140 | 0.0643 | 0.1191 | 0.6056 |