High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1189 | 718 | 4088 | 19318 | 453.0 | 106.58 | 96.23 | 99.59 | 325 | 357 | 386 | 412 | 441 | 469 | 504 | 546 | 607 | 0.0500 | 965 | 1.115 | 111.23 | 32.65 | 1 | 0.0624 | 255 | 0.0007 | 67.51 | 7.409 | 0.1424 | 216555.0 | 109000000 | 57400000000 | 31500000000000 | 0.4176 | 0.2368 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0042 | 0.0003 | 0.0275 | 0.0040 | 0.0803 | 0.0242 | 0.1695 | 0.0594 | 0.1357 | 0.0548 | 0.1682 | 0.0698 | 0.4134 | 0.7875 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0100 | 0.0017 | 0.0344 | 0.0160 | 0.0821 | 0.0397 | 0.0581 | 0.0242 | 0.0865 | 0.0410 | 0.7264 | 0.8774 | 0.0012 | 0.0071 | 0.0084 | 0.0000 | 0.0096 | 0.0249 | 0.0646 | 0.1068 | 0.0969 | 0.1459 | 0.1352 | 0.1851 | 0.1172 | 0.1281 | 0.1148 | 0.1637 | 0.4522 | 0.2384 | 0.0016 | 0.0043 | 0.0070 | 0.0290 | 0.0774 | 0.1198 | 0.0956 | 0.1263 | 0.5390 | 8 | 11 | 16 | 33 | 63 | 99 | 134 | 174 | 230 | 0.0320 | 16.16 | 5.428 | 0.4394 | 19177.9 | 5220000 | 1780000000 | 719000000000 | 0.4849 | 0.1488 | 0.0329 | 0.0012 | 0.1667 | 0.0102 | 0.2528 | 0.0730 | 0.1924 | 0.1400 | 0.1450 | 0.1900 | 0.1015 | 0.2083 | 0.0551 | 0.1299 | 0.0343 | 0.1220 | 0.0193 | 0.1254 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0020 | 0.0012 | 0.0104 | 0.0077 | 0.0520 | 0.0427 | 0.0878 | 0.0780 | 0.0668 | 0.0541 | 0.0945 | 0.0813 | 0.6857 | 0.7349 | 0.0007 | 0.0007 | 0.0022 | 0.0028 | 0.0048 | 0.0102 | 0.0188 | 0.0254 | 0.0667 | 0.0816 | 0.1172 | 0.1331 | 0.0893 | 0.0932 | 0.1224 | 0.1264 | 0.5778 | 0.5265 | 0.0004 | 0.0004 | 0.0035 | 0.0151 | 0.0545 | 0.1053 | 0.0729 | 0.1062 | 0.6416 | |||
BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 267 | 437 | 13592 | 31269 | 301.0 | 63.57 | 169.76 | 203.21 | 225 | 246 | 263 | 279 | 295 | 313 | 331 | 353 | 386 | 0.0450 | 1407 | 0.991 | 116.62 | 32.28 | 1 | 0.0211 | 287 | 0.0005 | 80.82 | 7.811 | 0.1322 | 94652.1 | 31000000 | 10600000000 | 3760000000000 | 0.4501 | 0.1998 | 0.0000 | 0.0000 | 0.0006 | 0.0002 | 0.0033 | 0.0002 | 0.0168 | 0.0009 | 0.0656 | 0.0133 | 0.1325 | 0.0320 | 0.1576 | 0.0360 | 0.1861 | 0.0572 | 0.4376 | 0.8603 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0001 | 0.0063 | 0.0004 | 0.0276 | 0.0084 | 0.0557 | 0.0188 | 0.0701 | 0.0154 | 0.0900 | 0.0249 | 0.7485 | 0.9321 | 0.0051 | 0.0171 | 0.0085 | 0.0240 | 0.0315 | 0.0719 | 0.0817 | 0.1199 | 0.1430 | 0.1747 | 0.1750 | 0.1695 | 0.1222 | 0.0925 | 0.1384 | 0.1318 | 0.2946 | 0.1986 | 0.0011 | 0.0024 | 0.0080 | 0.0318 | 0.0799 | 0.1235 | 0.1033 | 0.1392 | 0.5107 | 16 | 20 | 25 | 36 | 65 | 122 | 216 | 331 | 478 | 0.0295 | 54.42 | 5.957 | 0.4239 | 70109.3 | 38900000 | 25400000000 | 18600000000000 | 0.4659 | 0.1579 | 0.1220 | 0.0013 | 0.3239 | 0.0267 | 0.3147 | 0.2497 | 0.1092 | 0.2318 | 0.0683 | 0.1799 | 0.0358 | 0.1321 | 0.0147 | 0.0764 | 0.0073 | 0.0559 | 0.0041 | 0.0461 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0024 | 0.0013 | 0.0139 | 0.0099 | 0.0651 | 0.0580 | 0.1046 | 0.0910 | 0.0733 | 0.0686 | 0.1102 | 0.1024 | 0.6295 | 0.6682 | 0.0002 | 0.0003 | 0.0011 | 0.0020 | 0.0039 | 0.0045 | 0.0192 | 0.0256 | 0.0810 | 0.0887 | 0.1246 | 0.1262 | 0.0858 | 0.0977 | 0.1320 | 0.1374 | 0.5522 | 0.5175 | 0.0001 | 0.0012 | 0.0027 | 0.0147 | 0.0721 | 0.1162 | 0.0811 | 0.1158 | 0.5962 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 923 | 749 | 18485 | 19144 | 337.4 | 48.91 | 148.53 | 162.19 | 268 | 300 | 318 | 331 | 344 | 355 | 367 | 380 | 396 | 0.0705 | 1349 | 1.142 | 100.72 | 39.20 | 2 | 0.0147 | 271 | 0.0025 | 9.90 | 6.327 | 0.3429 | 116234.0 | 40800000 | 14500000000 | 5230000000000 | 0.4218 | 0.2181 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0027 | 0.0001 | 0.0083 | 0.0008 | 0.0174 | 0.0071 | 0.0285 | 0.0145 | 0.0316 | 0.0074 | 0.0551 | 0.0119 | 0.8546 | 0.9581 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0001 | 0.0022 | 0.0008 | 0.0085 | 0.0071 | 0.0136 | 0.0145 | 0.0122 | 0.0074 | 0.0186 | 0.0119 | 0.9443 | 0.9581 | 0.0326 | 0.0000 | 0.0692 | 0.0000 | 0.0794 | 0.0000 | 0.1090 | 0.0000 | 0.1517 | 0.0000 | 0.1415 | 0.0000 | 0.1395 | 0.0000 | 0.1446 | 0.0000 | 0.1324 | 0.0000 | 0.0028 | 0.0050 | 0.0091 | 0.0138 | 0.0293 | 0.0412 | 0.0457 | 0.0737 | 0.7793 | 23 | 31 | 42 | 57 | 77 | 109 | 167 | 256 | 387 | 0.0183 | 13.36 | 5.441 | 0.5104 | 48364.8 | 22700000 | 12800000000 | 8140000000000 | 0.3890 | 0.2609 | 0.0233 | 0.0013 | 0.0952 | 0.0085 | 0.1700 | 0.0530 | 0.1578 | 0.1011 | 0.1966 | 0.1512 | 0.1445 | 0.1702 | 0.0908 | 0.1386 | 0.0714 | 0.1404 | 0.0504 | 0.2358 | 0.0001 | 0.0003 | 0.0008 | 0.0009 | 0.0026 | 0.0044 | 0.0128 | 0.0124 | 0.0492 | 0.0417 | 0.0708 | 0.0661 | 0.0547 | 0.0448 | 0.0827 | 0.0706 | 0.7262 | 0.7587 | 0.0007 | 0.0006 | 0.0009 | 0.0017 | 0.0035 | 0.0058 | 0.0196 | 0.0235 | 0.0581 | 0.0707 | 0.0989 | 0.0946 | 0.0629 | 0.0773 | 0.0941 | 0.1006 | 0.6612 | 0.6252 | 0.0000 | 0.0010 | 0.0043 | 0.0159 | 0.0522 | 0.0864 | 0.0570 | 0.0870 | 0.6963 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 400 | 407 | 6276 | 11399 | 375.7 | 86.02 | 140.41 | 164.45 | 245 | 323 | 357 | 378 | 396 | 413 | 428 | 444 | 463 | 0.0798 | 910 | 1.138 | 23.43 | 8.49 | 5 | 0.0099 | 62 | 0.0020 | 19.90 | 6.638 | 0.2782 | 148520.0 | 60600000 | 25300000000 | 10700000000000 | 0.3938 | 0.2401 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0021 | 0.0000 | 0.0137 | 0.0000 | 0.0354 | 0.0108 | 0.0722 | 0.0252 | 0.0748 | 0.0104 | 0.1107 | 0.0183 | 0.6891 | 0.9352 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0137 | 0.0108 | 0.0298 | 0.0252 | 0.0216 | 0.0104 | 0.0319 | 0.0169 | 0.9017 | 0.9367 | 0.0072 | 1.0000 | 0.0184 | 0.0000 | 0.0419 | 0.0000 | 0.0593 | 0.0000 | 0.0992 | 0.0000 | 0.1329 | 0.0000 | 0.1299 | 0.0000 | 0.1227 | 0.0000 | 0.3885 | 0.0000 | 0.0000 | 0.0010 | 0.0031 | 0.0067 | 0.0347 | 0.0601 | 0.0515 | 0.0772 | 0.7656 | 9 | 11 | 15 | 29 | 67 | 119 | 185 | 272 | 389 | 0.0593 | 7.25 | 4.451 | 0.5348 | 46754.1 | 20300000 | 10200000000 | 5650000000000 | 0.4511 | 0.1880 | 0.0237 | 0.0010 | 0.1225 | 0.0110 | 0.2381 | 0.0628 | 0.1729 | 0.1187 | 0.1275 | 0.1830 | 0.1265 | 0.1945 | 0.0810 | 0.1237 | 0.0632 | 0.1062 | 0.0445 | 0.1990 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0017 | 0.0009 | 0.0089 | 0.0072 | 0.0450 | 0.0402 | 0.0820 | 0.0693 | 0.0542 | 0.0504 | 0.0858 | 0.0775 | 0.7214 | 0.7543 | 0.0003 | 0.0003 | 0.0030 | 0.0015 | 0.0041 | 0.0034 | 0.0160 | 0.0153 | 0.0574 | 0.0644 | 0.0907 | 0.1103 | 0.0655 | 0.0754 | 0.1045 | 0.1051 | 0.6586 | 0.6243 | 0.0002 | 0.0002 | 0.0019 | 0.0112 | 0.0594 | 0.0827 | 0.0622 | 0.0946 | 0.6875 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1104 | 606 | 7792 | 17317 | 455.1 | 84.64 | 91.04 | 159.85 | 350 | 380 | 405 | 428 | 449 | 472 | 497 | 528 | 568 | 0.0587 | 1017 | 0.843 | 136.49 | 39.96 | 1 | 0.0508 | 396 | 0.0009 | 41.02 | 7.256 | 0.1774 | 214248.0 | 104000000 | 52400000000 | 27200000000000 | 0.4390 | 0.2040 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0136 | 0.0005 | 0.0498 | 0.0107 | 0.1097 | 0.0237 | 0.1108 | 0.0193 | 0.1486 | 0.0344 | 0.5627 | 0.9113 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0024 | 0.0000 | 0.0058 | 0.0004 | 0.0229 | 0.0095 | 0.0478 | 0.0189 | 0.0484 | 0.0112 | 0.0635 | 0.0227 | 0.8089 | 0.9373 | 0.0050 | 0.0153 | 0.0059 | 0.0153 | 0.0243 | 0.0458 | 0.0703 | 0.1756 | 0.1456 | 0.1221 | 0.1816 | 0.1603 | 0.1364 | 0.0916 | 0.1356 | 0.1069 | 0.2954 | 0.2672 | 0.0019 | 0.0038 | 0.0059 | 0.0261 | 0.0676 | 0.1051 | 0.0997 | 0.1070 | 0.5829 | 5 | 6 | 7 | 9 | 11 | 25 | 76 | 148 | 295 | 0.1599 | 22.17 | 4.036 | 0.5973 | 33837.1 | 18800000 | 12800000000 | 9900000000000 | 0.6360 | 0.0673 | 0.0357 | 0.0021 | 0.1417 | 0.0167 | 0.2200 | 0.0889 | 0.1536 | 0.1271 | 0.1497 | 0.1836 | 0.1249 | 0.1857 | 0.0694 | 0.1130 | 0.0565 | 0.1130 | 0.0486 | 0.1700 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0006 | 0.0003 | 0.0113 | 0.0062 | 0.0430 | 0.0382 | 0.0708 | 0.0689 | 0.0549 | 0.0430 | 0.0815 | 0.0753 | 0.7371 | 0.7679 | 0.0002 | 0.0000 | 0.0005 | 0.0010 | 0.0049 | 0.0052 | 0.0117 | 0.0160 | 0.0608 | 0.0640 | 0.0963 | 0.1006 | 0.0629 | 0.0694 | 0.0974 | 0.1091 | 0.6653 | 0.6349 | 0.0002 | 0.0006 | 0.0023 | 0.0121 | 0.0489 | 0.0886 | 0.0606 | 0.0917 | 0.6949 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 202 | 300 | 6785 | 14162 | 73.6 | 17.99 | 128.75 | 204.22 | 55 | 60 | 64 | 67 | 70 | 74 | 78 | 85 | 98 | 0.0703 | 996 | 0.964 | 72.80 | 24.35 | 1 | 0.0280 | 190 | 0.0034 | 16.24 | 6.105 | 0.2850 | 5739.9 | 477688 | 42700000 | 4120000000 | 0.4408 | 0.2110 | 0.0005 | 0.0000 | 0.0039 | 0.0005 | 0.0122 | 0.0021 | 0.0270 | 0.0047 | 0.0766 | 0.0226 | 0.1354 | 0.0389 | 0.1541 | 0.0501 | 0.2125 | 0.0784 | 0.3779 | 0.8028 | 0.0002 | 0.0000 | 0.0015 | 0.0001 | 0.0044 | 0.0000 | 0.0115 | 0.0003 | 0.0412 | 0.0127 | 0.0738 | 0.0228 | 0.0842 | 0.0195 | 0.1337 | 0.0408 | 0.6495 | 0.9038 | 0.0089 | 0.0082 | 0.0124 | 0.0392 | 0.0231 | 0.0351 | 0.0738 | 0.1072 | 0.1120 | 0.1691 | 0.1431 | 0.1794 | 0.1182 | 0.1381 | 0.1476 | 0.1196 | 0.3609 | 0.2041 | 0.0051 | 0.0116 | 0.0260 | 0.0619 | 0.0952 | 0.1284 | 0.1208 | 0.1302 | 0.4208 | 12 | 14 | 16 | 19 | 29 | 64 | 131 | 219 | 365 | 0.0796 | 32.45 | 4.690 | 0.5502 | 58277.5 | 46900000 | 56200000000 | 88300000000000 | 0.5837 | 0.1324 | 0.0408 | 0.0021 | 0.1841 | 0.0191 | 0.2326 | 0.0908 | 0.1830 | 0.1300 | 0.1709 | 0.1990 | 0.1158 | 0.1879 | 0.0364 | 0.1423 | 0.0254 | 0.1147 | 0.0110 | 0.1141 | 0.0008 | 0.0004 | 0.0008 | 0.0017 | 0.0017 | 0.0017 | 0.0080 | 0.0075 | 0.0431 | 0.0368 | 0.0772 | 0.0632 | 0.0574 | 0.0462 | 0.1056 | 0.0896 | 0.7054 | 0.7529 | 0.0008 | 0.0006 | 0.0008 | 0.0020 | 0.0029 | 0.0050 | 0.0130 | 0.0190 | 0.0619 | 0.0781 | 0.1060 | 0.1085 | 0.0824 | 0.0930 | 0.1331 | 0.1355 | 0.5993 | 0.5582 | 0.0000 | 0.0009 | 0.0016 | 0.0108 | 0.0498 | 0.0912 | 0.0683 | 0.1170 | 0.6604 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1139 | 881 | 6326 | 14317 | 189.9 | 47.31 | 165.02 | 129.26 | 138 | 151 | 161 | 171 | 182 | 193 | 206 | 224 | 252 | 0.0773 | 1106 | 1.024 | 100.80 | 38.29 | 1 | 0.0438 | 277 | 0.0012 | 42.09 | 7.012 | 0.1876 | 38280.7 | 8230000 | 1890000000 | 462000000000 | 0.4259 | 0.2291 | 0.0005 | 0.0000 | 0.0013 | 0.0000 | 0.0057 | 0.0000 | 0.0234 | 0.0019 | 0.0776 | 0.0210 | 0.1558 | 0.0447 | 0.1631 | 0.0445 | 0.1831 | 0.0635 | 0.3895 | 0.8244 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0000 | 0.0098 | 0.0003 | 0.0319 | 0.0121 | 0.0718 | 0.0241 | 0.0706 | 0.0168 | 0.0970 | 0.0254 | 0.7152 | 0.9213 | 0.0052 | 0.0064 | 0.0103 | 0.0107 | 0.0207 | 0.0258 | 0.0767 | 0.0794 | 0.1259 | 0.1803 | 0.1759 | 0.1674 | 0.1190 | 0.1180 | 0.1250 | 0.1545 | 0.3414 | 0.2575 | 0.0007 | 0.0055 | 0.0117 | 0.0371 | 0.0950 | 0.1273 | 0.1185 | 0.1383 | 0.4659 | 34 | 48 | 69 | 97 | 132 | 170 | 214 | 268 | 354 | 0.0028 | 59.79 | 6.896 | 0.2662 | 43937.1 | 15200000 | 6170000000 | 2820000000000 | 0.5199 | 0.1445 | 0.0243 | 0.0025 | 0.1004 | 0.0068 | 0.2160 | 0.0533 | 0.1831 | 0.1121 | 0.1711 | 0.1528 | 0.1263 | 0.1873 | 0.0814 | 0.1483 | 0.0675 | 0.1416 | 0.0300 | 0.1953 | 0.0008 | 0.0007 | 0.0008 | 0.0002 | 0.0040 | 0.0028 | 0.0205 | 0.0158 | 0.0656 | 0.0457 | 0.0960 | 0.0802 | 0.0795 | 0.0679 | 0.1224 | 0.0924 | 0.6103 | 0.6942 | 0.0013 | 0.0018 | 0.0055 | 0.0060 | 0.0103 | 0.0189 | 0.0352 | 0.0463 | 0.0967 | 0.1178 | 0.1415 | 0.1568 | 0.1118 | 0.1307 | 0.1417 | 0.1494 | 0.4561 | 0.3722 | 0.0007 | 0.0012 | 0.0066 | 0.0298 | 0.0752 | 0.1185 | 0.1015 | 0.1342 | 0.5323 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 787 | 786 | 14112 | 32367 | 245.5 | 77.16 | 146.77 | 228.26 | 156 | 185 | 205 | 221 | 237 | 254 | 274 | 301 | 345 | 0.0488 | 1581 | 0.669 | 148.12 | 27.73 | 3 | 0.0257 | 363 | 0.0006 | 60.19 | 7.782 | 0.1687 | 66225.0 | 19500000 | 6230000000 | 2150000000000 | 0.4164 | 0.2099 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0068 | 0.0005 | 0.0211 | 0.0043 | 0.0673 | 0.0249 | 0.1414 | 0.0502 | 0.1309 | 0.0527 | 0.1587 | 0.0666 | 0.4724 | 0.8007 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0025 | 0.0003 | 0.0074 | 0.0026 | 0.0218 | 0.0131 | 0.0526 | 0.0251 | 0.0492 | 0.0237 | 0.0741 | 0.0308 | 0.7916 | 0.9043 | 0.0010 | 0.0021 | 0.0033 | 0.0076 | 0.0118 | 0.0125 | 0.0393 | 0.0569 | 0.1035 | 0.1090 | 0.1432 | 0.1444 | 0.0996 | 0.0938 | 0.1288 | 0.1146 | 0.4695 | 0.4590 | 0.0005 | 0.0024 | 0.0074 | 0.0199 | 0.0565 | 0.1073 | 0.0842 | 0.1154 | 0.6063 | 13 | 15 | 17 | 22 | 34 | 66 | 132 | 244 | 448 | 0.0654 | 39.84 | 4.972 | 0.5439 | 73640.4 | 55300000 | 50400000000 | 51700000000000 | 0.5011 | 0.1602 | 0.0623 | 0.0031 | 0.2185 | 0.0242 | 0.2928 | 0.1386 | 0.1538 | 0.1668 | 0.1059 | 0.2014 | 0.0738 | 0.1699 | 0.0455 | 0.1175 | 0.0254 | 0.0808 | 0.0220 | 0.0977 | 0.0000 | 0.0003 | 0.0009 | 0.0002 | 0.0020 | 0.0009 | 0.0125 | 0.0097 | 0.0604 | 0.0529 | 0.0922 | 0.0798 | 0.0683 | 0.0642 | 0.1028 | 0.0895 | 0.6609 | 0.7026 | 0.0001 | 0.0004 | 0.0013 | 0.0019 | 0.0031 | 0.0054 | 0.0184 | 0.0221 | 0.0771 | 0.0786 | 0.1154 | 0.1217 | 0.0827 | 0.0911 | 0.1160 | 0.1245 | 0.5858 | 0.5543 | 0.0004 | 0.0009 | 0.0021 | 0.0159 | 0.0682 | 0.1066 | 0.0762 | 0.1087 | 0.6210 | |||
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1018 | 588 | 3811 | 2194 | 152.8 | 45.25 | 165.29 | 120.38 | 109 | 118 | 126 | 134 | 142 | 151 | 164 | 180 | 214 | 0.2334 | 512 | 1.053 | 95.88 | 21.84 | 1 | 0.0559 | 213 | 0.0019 | 30.81 | 6.595 | 0.2281 | 25408.3 | 4650000 | 946000000 | 214000000000 | 0.3988 | 0.2432 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0000 | 0.0266 | 0.0015 | 0.1000 | 0.0318 | 0.1613 | 0.0588 | 0.1678 | 0.0558 | 0.1730 | 0.0780 | 0.3604 | 0.7742 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0053 | 0.0000 | 0.0145 | 0.0008 | 0.0469 | 0.0184 | 0.0800 | 0.0301 | 0.0793 | 0.0235 | 0.0959 | 0.0379 | 0.6781 | 0.8893 | 0.0014 | 0.0000 | 0.0201 | 0.0000 | 0.0086 | 0.0026 | 0.0459 | 0.0741 | 0.1119 | 0.1481 | 0.1607 | 0.1984 | 0.0947 | 0.1085 | 0.1349 | 0.1614 | 0.4218 | 0.3069 | 0.0040 | 0.0094 | 0.0101 | 0.0330 | 0.0808 | 0.1359 | 0.0969 | 0.1151 | 0.5148 | 45 | 64 | 85 | 108 | 136 | 167 | 200 | 252 | 322 | 0.0021 | 74.42 | 6.577 | 0.2161 | 41805.4 | 14100000 | 5770000000 | 2690000000000 | 0.5152 | 0.1357 | 0.0346 | 0.0000 | 0.1364 | 0.0171 | 0.2165 | 0.0798 | 0.1667 | 0.1277 | 0.1688 | 0.1631 | 0.1190 | 0.1836 | 0.0909 | 0.1072 | 0.0455 | 0.1482 | 0.0216 | 0.1733 | 0.0000 | 0.0000 | 0.0009 | 0.0014 | 0.0097 | 0.0043 | 0.0292 | 0.0264 | 0.1205 | 0.0785 | 0.1763 | 0.1527 | 0.1045 | 0.0935 | 0.1523 | 0.1456 | 0.4066 | 0.4975 | 0.0030 | 0.0057 | 0.0045 | 0.0038 | 0.0285 | 0.0286 | 0.0615 | 0.0782 | 0.1529 | 0.1794 | 0.2144 | 0.2271 | 0.1229 | 0.1355 | 0.1439 | 0.1240 | 0.2684 | 0.2176 | 0.0011 | 0.0034 | 0.0202 | 0.0506 | 0.1406 | 0.1755 | 0.1260 | 0.1586 | 0.3240 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 770 | 548 | 4679 | 6669 | 137.8 | 37.32 | 193.13 | 136.78 | 97 | 107 | 115 | 123 | 132 | 140 | 151 | 165 | 188 | 0.1021 | 681 | 1.113 | 90.80 | 33.54 | 1 | 0.0524 | 245 | 0.0018 | 30.73 | 6.604 | 0.2167 | 20392.3 | 3250000 | 560000000 | 104000000000 | 0.4422 | 0.2057 | 0.0004 | 0.0000 | 0.0019 | 0.0000 | 0.0089 | 0.0007 | 0.0355 | 0.0024 | 0.1066 | 0.0257 | 0.1896 | 0.0591 | 0.1776 | 0.0651 | 0.1622 | 0.0905 | 0.3174 | 0.7565 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0043 | 0.0002 | 0.0097 | 0.0009 | 0.0441 | 0.0159 | 0.0819 | 0.0278 | 0.0802 | 0.0248 | 0.1044 | 0.0448 | 0.6745 | 0.8856 | 0.0054 | 0.0052 | 0.0086 | 0.0052 | 0.0119 | 0.0336 | 0.0627 | 0.1059 | 0.1568 | 0.2351 | 0.1859 | 0.2119 | 0.1092 | 0.0801 | 0.1557 | 0.1473 | 0.3038 | 0.1757 | 0.0015 | 0.0020 | 0.0085 | 0.0346 | 0.0989 | 0.1416 | 0.1145 | 0.1401 | 0.4583 | 42 | 70 | 97 | 128 | 161 | 203 | 250 | 305 | 391 | 0.0016 | 66.86 | 7.053 | 0.2296 | 56004.9 | 20500000 | 8680000000 | 4090000000000 | 0.5260 | 0.1564 | 0.0262 | 0.0016 | 0.1229 | 0.0056 | 0.2269 | 0.0334 | 0.1900 | 0.1091 | 0.1859 | 0.1851 | 0.1310 | 0.2201 | 0.0639 | 0.1584 | 0.0336 | 0.1421 | 0.0197 | 0.1445 | 0.0003 | 0.0007 | 0.0009 | 0.0007 | 0.0067 | 0.0024 | 0.0188 | 0.0163 | 0.0733 | 0.0544 | 0.1196 | 0.0928 | 0.0999 | 0.0728 | 0.1330 | 0.1079 | 0.5475 | 0.6521 | 0.0022 | 0.0017 | 0.0045 | 0.0063 | 0.0085 | 0.0150 | 0.0368 | 0.0600 | 0.1188 | 0.1298 | 0.1645 | 0.1997 | 0.1215 | 0.1298 | 0.1551 | 0.1558 | 0.3882 | 0.3018 | 0.0011 | 0.0032 | 0.0056 | 0.0275 | 0.0898 | 0.1479 | 0.1127 | 0.1437 | 0.4687 | |
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 912 | 233 | 5870 | 24688 | 277.0 | 63.32 | 98.44 | 168.31 | 201 | 221 | 239 | 254 | 270 | 286 | 305 | 329 | 365 | 0.0475 | 1173 | 1.191 | 103.82 | 38.01 | 1 | 0.0428 | 251 | 0.0007 | 63.63 | 7.502 | 0.1601 | 80724.4 | 24700000 | 7930000000 | 2660000000000 | 0.4510 | 0.1942 | 0.0003 | 0.0002 | 0.0008 | 0.0000 | 0.0031 | 0.0002 | 0.0165 | 0.0020 | 0.0684 | 0.0184 | 0.1377 | 0.0460 | 0.1419 | 0.0408 | 0.1640 | 0.0561 | 0.4673 | 0.8362 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0053 | 0.0009 | 0.0293 | 0.0110 | 0.0611 | 0.0250 | 0.0609 | 0.0155 | 0.0819 | 0.0242 | 0.7602 | 0.9234 | 0.0009 | 0.0028 | 0.0090 | 0.0056 | 0.0126 | 0.0306 | 0.0531 | 0.1142 | 0.1178 | 0.1783 | 0.1610 | 0.2256 | 0.1088 | 0.1226 | 0.1403 | 0.1448 | 0.3966 | 0.1755 | 0.0004 | 0.0041 | 0.0137 | 0.0375 | 0.0742 | 0.1187 | 0.0968 | 0.1246 | 0.5300 | 8 | 9 | 11 | 13 | 16 | 27 | 65 | 158 | 326 | 0.1748 | 15.56 | 4.062 | 0.6361 | 38015.9 | 21300000 | 14100000000 | 10500000000000 | 0.4506 | 0.1916 | 0.0704 | 0.0013 | 0.2291 | 0.0191 | 0.3221 | 0.1226 | 0.1709 | 0.2079 | 0.1033 | 0.2447 | 0.0648 | 0.1724 | 0.0207 | 0.1000 | 0.0122 | 0.0771 | 0.0066 | 0.0550 | 0.0003 | 0.0000 | 0.0009 | 0.0005 | 0.0010 | 0.0014 | 0.0081 | 0.0111 | 0.0458 | 0.0427 | 0.0835 | 0.0736 | 0.0487 | 0.0501 | 0.0777 | 0.0719 | 0.7339 | 0.7487 | 0.0002 | 0.0004 | 0.0005 | 0.0002 | 0.0019 | 0.0032 | 0.0112 | 0.0119 | 0.0561 | 0.0571 | 0.0878 | 0.0924 | 0.0591 | 0.0641 | 0.0930 | 0.0948 | 0.6903 | 0.6760 | 0.0002 | 0.0000 | 0.0017 | 0.0096 | 0.0502 | 0.0854 | 0.0527 | 0.0840 | 0.7161 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 501 | 504 | 10483 | 29050 | 333.7 | 87.79 | 177.85 | 262.57 | 236 | 272 | 293 | 313 | 331 | 350 | 372 | 400 | 442 | 0.0518 | 1504 | 0.386 | 149.64 | 20.59 | 5 | 0.0405 | 425 | 0.0005 | 88.21 | 7.897 | 0.1404 | 119081.0 | 44900000 | 17800000000 | 7380000000000 | 0.4581 | 0.1796 | 0.0000 | 0.0000 | 0.0012 | 0.0001 | 0.0040 | 0.0003 | 0.0124 | 0.0024 | 0.0524 | 0.0199 | 0.0976 | 0.0409 | 0.1048 | 0.0282 | 0.1371 | 0.0397 | 0.5905 | 0.8683 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0015 | 0.0000 | 0.0043 | 0.0009 | 0.0218 | 0.0129 | 0.0408 | 0.0249 | 0.0434 | 0.0140 | 0.0546 | 0.0203 | 0.8331 | 0.9269 | 0.0063 | 0.0043 | 0.0058 | 0.0029 | 0.0184 | 0.0200 | 0.0442 | 0.0428 | 0.0738 | 0.1056 | 0.1169 | 0.1469 | 0.1004 | 0.0984 | 0.1145 | 0.1213 | 0.5197 | 0.4579 | 0.0012 | 0.0029 | 0.0078 | 0.0171 | 0.0536 | 0.0699 | 0.0740 | 0.0962 | 0.6774 | 11 | 14 | 18 | 25 | 50 | 97 | 178 | 304 | 548 | 0.0648 | 33.20 | 5.292 | 0.5122 | 100572.0 | 82800000 | 82800000000 | 94100000000000 | 0.3716 | 0.2666 | 0.0296 | 0.0017 | 0.1361 | 0.0083 | 0.2160 | 0.0670 | 0.1652 | 0.1170 | 0.1568 | 0.1755 | 0.1326 | 0.1840 | 0.0774 | 0.1333 | 0.0483 | 0.1272 | 0.0380 | 0.1861 | 0.0001 | 0.0003 | 0.0009 | 0.0003 | 0.0034 | 0.0025 | 0.0112 | 0.0111 | 0.0428 | 0.0397 | 0.0676 | 0.0625 | 0.0535 | 0.0451 | 0.0718 | 0.0631 | 0.7487 | 0.7755 | 0.0005 | 0.0007 | 0.0015 | 0.0023 | 0.0044 | 0.0056 | 0.0156 | 0.0203 | 0.0529 | 0.0545 | 0.0833 | 0.0881 | 0.0667 | 0.0649 | 0.0827 | 0.0819 | 0.6924 | 0.6817 | 0.0002 | 0.0008 | 0.0029 | 0.0164 | 0.0438 | 0.0782 | 0.0630 | 0.0794 | 0.7154 | |||
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 841 | 100 | 7377 | 24941 | 386.3 | 96.75 | 88.88 | 190.82 | 262 | 298 | 330 | 360 | 385 | 408 | 433 | 466 | 515 | 0.0500 | 1246 | 0.563 | 94.76 | 26.17 | 2 | 0.0409 | 302 | 0.0008 | 47.55 | 7.415 | 0.1751 | 158588.0 | 68800000 | 31400000000 | 15000000000000 | 0.4311 | 0.2177 | 0.0002 | 0.0000 | 0.0031 | 0.0005 | 0.0070 | 0.0012 | 0.0283 | 0.0041 | 0.0813 | 0.0252 | 0.1505 | 0.0529 | 0.1401 | 0.0558 | 0.1607 | 0.0799 | 0.4286 | 0.7805 | 0.0000 | 0.0000 | 0.0011 | 0.0001 | 0.0023 | 0.0003 | 0.0099 | 0.0018 | 0.0340 | 0.0163 | 0.0593 | 0.0332 | 0.0508 | 0.0272 | 0.0661 | 0.0402 | 0.7764 | 0.8808 | 0.0040 | 0.0130 | 0.0066 | 0.0238 | 0.0139 | 0.0563 | 0.0615 | 0.0909 | 0.1315 | 0.1970 | 0.1606 | 0.1710 | 0.1269 | 0.1255 | 0.1401 | 0.1299 | 0.3549 | 0.1926 | 0.0005 | 0.0014 | 0.0043 | 0.0220 | 0.0674 | 0.1016 | 0.1003 | 0.1272 | 0.5753 | 4 | 5 | 7 | 8 | 10 | 12 | 18 | 103 | 322 | 0.1971 | 13.23 | 3.393 | 0.6457 | 44309.3 | 31100000 | 25500000000 | 23000000000000 | 0.4510 | 0.1554 | 0.0309 | 0.0028 | 0.1373 | 0.0130 | 0.2921 | 0.0763 | 0.2205 | 0.1516 | 0.1431 | 0.2140 | 0.0986 | 0.1898 | 0.0271 | 0.1395 | 0.0213 | 0.1116 | 0.0290 | 0.1014 | 0.0000 | 0.0003 | 0.0009 | 0.0005 | 0.0007 | 0.0016 | 0.0037 | 0.0063 | 0.0213 | 0.0191 | 0.0374 | 0.0318 | 0.0250 | 0.0278 | 0.0407 | 0.0377 | 0.8703 | 0.8748 | 0.0000 | 0.0002 | 0.0008 | 0.0004 | 0.0004 | 0.0019 | 0.0063 | 0.0064 | 0.0259 | 0.0282 | 0.0468 | 0.0526 | 0.0377 | 0.0404 | 0.0539 | 0.0614 | 0.8281 | 0.8084 | 0.0000 | 0.0004 | 0.0008 | 0.0042 | 0.0213 | 0.0423 | 0.0293 | 0.0477 | 0.8540 | |
MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 861 | 186 | 12331 | 15671 | 289.1 | 82.48 | 116.02 | 160.19 | 201 | 225 | 243 | 260 | 276 | 292 | 314 | 345 | 400 | 0.0849 | 1331 | 0.663 | 177.34 | 56.46 | 4 | 0.0431 | 532 | 0.0008 | 58.20 | 7.495 | 0.1717 | 90380.5 | 30600000 | 11200000000 | 4470000000000 | 0.4343 | 0.2144 | 0.0007 | 0.0000 | 0.0013 | 0.0002 | 0.0081 | 0.0007 | 0.0252 | 0.0037 | 0.0800 | 0.0238 | 0.1386 | 0.0531 | 0.1412 | 0.0533 | 0.1670 | 0.0739 | 0.4380 | 0.7912 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0079 | 0.0009 | 0.0344 | 0.0131 | 0.0694 | 0.0240 | 0.0655 | 0.0205 | 0.0934 | 0.0333 | 0.7273 | 0.9081 | 0.0029 | 0.0034 | 0.0074 | 0.0068 | 0.0153 | 0.0316 | 0.0422 | 0.0769 | 0.1071 | 0.1435 | 0.1468 | 0.1973 | 0.1038 | 0.0991 | 0.1443 | 0.1307 | 0.4301 | 0.3108 | 0.0013 | 0.0040 | 0.0106 | 0.0361 | 0.0748 | 0.1272 | 0.0958 | 0.1105 | 0.5396 | 7 | 10 | 13 | 22 | 43 | 73 | 127 | 212 | 335 | 0.0704 | 13.83 | 4.641 | 0.5316 | 39120.6 | 20200000 | 14100000000 | 12400000000000 | 0.5640 | 0.1235 | 0.0406 | 0.0033 | 0.1589 | 0.0200 | 0.2525 | 0.0850 | 0.1954 | 0.1426 | 0.1432 | 0.1904 | 0.1043 | 0.1814 | 0.0579 | 0.1368 | 0.0281 | 0.1111 | 0.0190 | 0.1295 | 0.0000 | 0.0006 | 0.0009 | 0.0012 | 0.0034 | 0.0027 | 0.0101 | 0.0123 | 0.0575 | 0.0454 | 0.0885 | 0.0709 | 0.0600 | 0.0580 | 0.0942 | 0.0801 | 0.6855 | 0.7288 | 0.0002 | 0.0005 | 0.0009 | 0.0015 | 0.0041 | 0.0040 | 0.0175 | 0.0184 | 0.0723 | 0.0875 | 0.1159 | 0.1187 | 0.0771 | 0.0804 | 0.1104 | 0.1200 | 0.6016 | 0.5689 | 0.0000 | 0.0012 | 0.0028 | 0.0153 | 0.0630 | 0.1041 | 0.0675 | 0.1093 | 0.6367 | |
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 349 | 807 | 6538 | 12626 | 588.0 | 86.69 | 128.31 | 222.66 | 469 | 530 | 562 | 584 | 602 | 620 | 637 | 657 | 683 | 0.0673 | 850 | 0.775 | 146.56 | 30.15 | 1 | 0.0509 | 333 | 0.0010 | 44.42 | 7.238 | 0.1938 | 353259.0 | 216000000 | 134000000000 | 83900000000000 | 0.4229 | 0.2180 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0002 | 0.0197 | 0.0106 | 0.0355 | 0.0173 | 0.0365 | 0.0112 | 0.0673 | 0.0176 | 0.8370 | 0.9433 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0129 | 0.0106 | 0.0221 | 0.0173 | 0.0201 | 0.0112 | 0.0312 | 0.0176 | 0.9121 | 0.9433 | 0.0276 | 0.0000 | 0.0379 | 0.0000 | 0.0379 | 0.0000 | 0.1241 | 0.0000 | 0.1310 | 0.0000 | 0.1586 | 0.0000 | 0.1241 | 0.0000 | 0.0931 | 0.0000 | 0.2655 | 0.0000 | 0.0011 | 0.0034 | 0.0053 | 0.0169 | 0.0344 | 0.0573 | 0.0655 | 0.0922 | 0.7238 | 11 | 13 | 16 | 21 | 29 | 46 | 87 | 188 | 404 | 0.1397 | 11.93 | 3.675 | 0.6149 | 66036.9 | 54600000 | 58200000000 | 74400000000000 | 0.4876 | 0.1751 | 0.0820 | 0.0077 | 0.2182 | 0.0463 | 0.2753 | 0.1683 | 0.1406 | 0.1143 | 0.1083 | 0.1550 | 0.0849 | 0.1907 | 0.0395 | 0.1066 | 0.0249 | 0.0863 | 0.0264 | 0.1248 | 0.0000 | 0.0005 | 0.0009 | 0.0010 | 0.0026 | 0.0022 | 0.0131 | 0.0124 | 0.0707 | 0.0604 | 0.0993 | 0.0897 | 0.0678 | 0.0592 | 0.1013 | 0.0905 | 0.6443 | 0.6841 | 0.0000 | 0.0004 | 0.0004 | 0.0004 | 0.0039 | 0.0019 | 0.0218 | 0.0250 | 0.0761 | 0.0832 | 0.1208 | 0.1271 | 0.0778 | 0.0847 | 0.1127 | 0.1144 | 0.5866 | 0.5630 | 0.0003 | 0.0003 | 0.0029 | 0.0147 | 0.0809 | 0.1055 | 0.0723 | 0.1125 | 0.6106 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 991 | 744 | 5862 | 10539 | 192.1 | 52.46 | 146.42 | 108.37 | 131 | 149 | 162 | 172 | 184 | 197 | 213 | 234 | 265 | 0.0895 | 943 | 0.544 | 198.46 | 47.51 | 3 | 0.0942 | 552 | 0.0009 | 52.02 | 7.253 | 0.1584 | 39655.6 | 8770000 | 2070000000 | 520000000000 | 0.4554 | 0.1871 | 0.0006 | 0.0000 | 0.0034 | 0.0000 | 0.0096 | 0.0008 | 0.0355 | 0.0041 | 0.1058 | 0.0324 | 0.1811 | 0.0725 | 0.1481 | 0.0680 | 0.1700 | 0.0980 | 0.3461 | 0.7242 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0018 | 0.0002 | 0.0095 | 0.0011 | 0.0433 | 0.0190 | 0.0801 | 0.0417 | 0.0708 | 0.0310 | 0.1006 | 0.0475 | 0.6930 | 0.8596 | 0.0016 | 0.0115 | 0.0032 | 0.0115 | 0.0206 | 0.0249 | 0.0562 | 0.1109 | 0.1267 | 0.1625 | 0.1544 | 0.2065 | 0.1378 | 0.1013 | 0.1394 | 0.1415 | 0.3603 | 0.2294 | 0.0015 | 0.0043 | 0.0081 | 0.0340 | 0.0858 | 0.1291 | 0.1071 | 0.1272 | 0.5029 | 31 | 47 | 66 | 92 | 121 | 155 | 191 | 236 | 300 | 0.0060 | 18.43 | 5.996 | 0.3631 | 33180.2 | 9590000 | 3250000000 | 1230000000000 | 0.4729 | 0.1780 | 0.0201 | 0.0016 | 0.0959 | 0.0049 | 0.2214 | 0.0320 | 0.2086 | 0.0781 | 0.1735 | 0.1676 | 0.1322 | 0.2150 | 0.0786 | 0.1567 | 0.0491 | 0.1594 | 0.0206 | 0.1847 | 0.0000 | 0.0002 | 0.0009 | 0.0011 | 0.0035 | 0.0017 | 0.0153 | 0.0096 | 0.0587 | 0.0403 | 0.0895 | 0.0744 | 0.0784 | 0.0610 | 0.1174 | 0.0937 | 0.6362 | 0.7182 | 0.0008 | 0.0014 | 0.0033 | 0.0090 | 0.0066 | 0.0118 | 0.0303 | 0.0451 | 0.0869 | 0.1121 | 0.1487 | 0.1637 | 0.1189 | 0.1168 | 0.1451 | 0.1569 | 0.4593 | 0.3832 | 0.0009 | 0.0016 | 0.0060 | 0.0218 | 0.0656 | 0.1141 | 0.1038 | 0.1319 | 0.5544 | |
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 686 | 761 | 4278 | 10329 | 575.0 | 101.74 | 209.00 | 348.06 | 451 | 485 | 515 | 540 | 564 | 591 | 619 | 660 | 717 | 0.0947 | 978 | 1.233 | 88.57 | 39.70 | 1 | 0.0570 | 244 | 0.0015 | 26.90 | 6.732 | 0.2213 | 340946.0 | 208000000 | 131000000000 | 85100000000000 | 0.4370 | 0.2089 | 0.0003 | 0.0002 | 0.0016 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0005 | 0.0491 | 0.0165 | 0.1035 | 0.0326 | 0.1032 | 0.0271 | 0.1478 | 0.0398 | 0.5865 | 0.8833 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0005 | 0.0000 | 0.0035 | 0.0002 | 0.0289 | 0.0138 | 0.0516 | 0.0248 | 0.0503 | 0.0145 | 0.0751 | 0.0227 | 0.7893 | 0.9239 | 0.0017 | 0.0000 | 0.0017 | 0.0408 | 0.0166 | 0.0510 | 0.0582 | 0.1633 | 0.1481 | 0.2041 | 0.1681 | 0.2245 | 0.0899 | 0.0714 | 0.1514 | 0.1633 | 0.3644 | 0.0816 | 0.0010 | 0.0000 | 0.0051 | 0.0314 | 0.0663 | 0.1352 | 0.1023 | 0.1180 | 0.5408 | 9 | 10 | 12 | 14 | 19 | 49 | 188 | 394 | 707 | 0.1793 | 74.24 | 4.505 | 0.5801 | 164813.0 | 178000000 | 227000000000 | 323000000000000 | 0.5252 | 0.1228 | 0.1229 | 0.0022 | 0.3301 | 0.0673 | 0.2337 | 0.2076 | 0.1108 | 0.1987 | 0.0723 | 0.2065 | 0.0723 | 0.1358 | 0.0313 | 0.0550 | 0.0193 | 0.0673 | 0.0072 | 0.0595 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0013 | 0.0020 | 0.0041 | 0.0055 | 0.0525 | 0.0486 | 0.0965 | 0.0858 | 0.0600 | 0.0532 | 0.0839 | 0.0776 | 0.7008 | 0.7272 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0014 | 0.0012 | 0.0090 | 0.0196 | 0.0690 | 0.0667 | 0.1063 | 0.1181 | 0.0788 | 0.0895 | 0.1095 | 0.1071 | 0.6259 | 0.5958 | 0.0000 | 0.0003 | 0.0000 | 0.0104 | 0.0509 | 0.1031 | 0.0686 | 0.0961 | 0.6707 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 346 | 701 | 14198 | 40387 | 106.4 | 32.10 | 146.17 | 188.92 | 72 | 82 | 90 | 96 | 103 | 110 | 118 | 129 | 144 | 0.0393 | 1589 | 0.755 | 201.22 | 48.27 | 2 | 0.0373 | 529 | 0.0026 | 18.07 | 6.363 | 0.2881 | 12345.6 | 1580000 | 229000000 | 39000000000 | 0.4708 | 0.1852 | 0.0007 | 0.0001 | 0.0041 | 0.0010 | 0.0119 | 0.0011 | 0.0333 | 0.0042 | 0.0850 | 0.0218 | 0.1598 | 0.0539 | 0.1708 | 0.0533 | 0.1970 | 0.0847 | 0.3372 | 0.7798 | 0.0002 | 0.0000 | 0.0011 | 0.0001 | 0.0015 | 0.0003 | 0.0096 | 0.0013 | 0.0331 | 0.0130 | 0.0687 | 0.0281 | 0.0706 | 0.0210 | 0.1052 | 0.0352 | 0.7101 | 0.9010 | 0.0061 | 0.0103 | 0.0105 | 0.0240 | 0.0243 | 0.0326 | 0.0723 | 0.1021 | 0.1348 | 0.1501 | 0.1713 | 0.1827 | 0.1203 | 0.1226 | 0.1413 | 0.1389 | 0.3190 | 0.2367 | 0.0017 | 0.0051 | 0.0119 | 0.0353 | 0.0818 | 0.1125 | 0.1127 | 0.1276 | 0.5114 | 12 | 14 | 17 | 21 | 38 | 97 | 181 | 289 | 433 | 0.0636 | 63.25 | 5.587 | 0.4594 | 57055.8 | 29900000 | 18300000000 | 12600000000000 | 0.5337 | 0.1336 | 0.0936 | 0.0033 | 0.2406 | 0.0356 | 0.2573 | 0.2023 | 0.1157 | 0.1813 | 0.1154 | 0.1677 | 0.0874 | 0.1514 | 0.0464 | 0.0816 | 0.0283 | 0.0770 | 0.0152 | 0.0996 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0022 | 0.0010 | 0.0084 | 0.0066 | 0.0488 | 0.0425 | 0.1001 | 0.0859 | 0.0667 | 0.0576 | 0.0957 | 0.0872 | 0.6770 | 0.7188 | 0.0006 | 0.0001 | 0.0009 | 0.0017 | 0.0039 | 0.0037 | 0.0107 | 0.0152 | 0.0648 | 0.0721 | 0.1272 | 0.1439 | 0.0905 | 0.0989 | 0.1204 | 0.1231 | 0.5809 | 0.5414 | 0.0005 | 0.0010 | 0.0023 | 0.0103 | 0.0565 | 0.1095 | 0.0807 | 0.1143 | 0.6250 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 680 | 551 | 5987 | 6093 | 134.6 | 38.08 | 176.05 | 235.22 | 92 | 104 | 113 | 122 | 129 | 138 | 148 | 161 | 182 | 0.1188 | 724 | 1.000 | 95.60 | 29.27 | 1 | 0.0403 | 241 | 0.0020 | 24.09 | 6.532 | 0.2581 | 19556.5 | 3090000 | 540000000 | 105000000000 | 0.4491 | 0.2026 | 0.0006 | 0.0000 | 0.0035 | 0.0004 | 0.0088 | 0.0006 | 0.0253 | 0.0021 | 0.0823 | 0.0225 | 0.1531 | 0.0497 | 0.1611 | 0.0584 | 0.1743 | 0.0871 | 0.3909 | 0.7792 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0031 | 0.0000 | 0.0090 | 0.0005 | 0.0374 | 0.0132 | 0.0593 | 0.0258 | 0.0654 | 0.0231 | 0.0842 | 0.0390 | 0.7408 | 0.8984 | 0.0009 | 0.0104 | 0.0128 | 0.0084 | 0.0239 | 0.0251 | 0.0632 | 0.0898 | 0.1376 | 0.1962 | 0.1709 | 0.1649 | 0.1043 | 0.1211 | 0.1564 | 0.1608 | 0.3299 | 0.2234 | 0.0023 | 0.0023 | 0.0095 | 0.0338 | 0.0834 | 0.1244 | 0.1085 | 0.1301 | 0.5059 | 10 | 11 | 13 | 16 | 34 | 115 | 229 | 352 | 553 | 0.1116 | 42.16 | 4.818 | 0.5374 | 86309.7 | 54700000 | 39600000000 | 31400000000000 | 0.5384 | 0.1532 | 0.0884 | 0.0052 | 0.2601 | 0.0551 | 0.2652 | 0.1627 | 0.1288 | 0.1890 | 0.0833 | 0.2008 | 0.0758 | 0.1444 | 0.0581 | 0.0866 | 0.0227 | 0.0735 | 0.0177 | 0.0827 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0020 | 0.0121 | 0.0068 | 0.0484 | 0.0419 | 0.0963 | 0.0971 | 0.0652 | 0.0532 | 0.0963 | 0.0789 | 0.6799 | 0.7201 | 0.0000 | 0.0006 | 0.0016 | 0.0017 | 0.0021 | 0.0058 | 0.0172 | 0.0221 | 0.0667 | 0.0813 | 0.1199 | 0.1371 | 0.0896 | 0.0936 | 0.1214 | 0.1174 | 0.5816 | 0.5404 | 0.0000 | 0.0014 | 0.0023 | 0.0136 | 0.0567 | 0.1068 | 0.0829 | 0.1036 | 0.6326 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 634 | 836 | 6694 | 23123 | 220.1 | 45.92 | 161.99 | 175.74 | 165 | 181 | 193 | 204 | 215 | 227 | 240 | 256 | 280 | 0.0480 | 1111 | 1.210 | 102.65 | 44.29 | 1 | 0.0420 | 281 | 0.0011 | 40.91 | 7.097 | 0.1838 | 50535.0 | 12100000 | 3040000000 | 797000000000 | 0.4401 | 0.2135 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0029 | 0.0002 | 0.0159 | 0.0003 | 0.0615 | 0.0172 | 0.1197 | 0.0311 | 0.1488 | 0.0369 | 0.1834 | 0.0515 | 0.4669 | 0.8628 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0062 | 0.0000 | 0.0277 | 0.0126 | 0.0551 | 0.0171 | 0.0627 | 0.0163 | 0.0885 | 0.0249 | 0.7582 | 0.9291 | 0.0046 | 0.0108 | 0.0147 | 0.0179 | 0.0394 | 0.0502 | 0.0879 | 0.1613 | 0.1319 | 0.1613 | 0.1712 | 0.1864 | 0.1071 | 0.1111 | 0.1328 | 0.0932 | 0.3104 | 0.2079 | 0.0013 | 0.0016 | 0.0090 | 0.0303 | 0.0940 | 0.1211 | 0.1137 | 0.1523 | 0.4767 | 11 | 13 | 18 | 38 | 92 | 162 | 235 | 308 | 417 | 0.0450 | 24.09 | 5.615 | 0.4490 | 57122.6 | 25900000 | 13700000000 | 8060000000000 | 0.4415 | 0.1960 | 0.0450 | 0.0017 | 0.1921 | 0.0096 | 0.3192 | 0.0939 | 0.1711 | 0.1707 | 0.1124 | 0.2071 | 0.0816 | 0.1996 | 0.0401 | 0.1194 | 0.0308 | 0.1084 | 0.0078 | 0.0896 | 0.0005 | 0.0001 | 0.0009 | 0.0005 | 0.0008 | 0.0016 | 0.0092 | 0.0074 | 0.0453 | 0.0386 | 0.0833 | 0.0715 | 0.0621 | 0.0516 | 0.0918 | 0.0767 | 0.7061 | 0.7520 | 0.0001 | 0.0007 | 0.0010 | 0.0017 | 0.0034 | 0.0074 | 0.0198 | 0.0214 | 0.0603 | 0.0717 | 0.1056 | 0.1113 | 0.0810 | 0.0864 | 0.1068 | 0.1131 | 0.6220 | 0.5862 | 0.0001 | 0.0006 | 0.0018 | 0.0130 | 0.0555 | 0.0911 | 0.0731 | 0.1019 | 0.6628 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 656 | 535 | 6091 | 20546 | 242.4 | 44.53 | 137.26 | 192.39 | 187 | 203 | 216 | 228 | 239 | 251 | 264 | 280 | 303 | 0.0476 | 979 | 1.098 | 86.73 | 30.00 | 1 | 0.0368 | 224 | 0.0009 | 51.40 | 7.200 | 0.1626 | 60738.6 | 15700000 | 4190000000 | 1150000000000 | 0.4279 | 0.2267 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0124 | 0.0005 | 0.0636 | 0.0142 | 0.1292 | 0.0326 | 0.1368 | 0.0323 | 0.1768 | 0.0541 | 0.4789 | 0.8663 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0008 | 0.0000 | 0.0040 | 0.0002 | 0.0280 | 0.0117 | 0.0548 | 0.0216 | 0.0579 | 0.0143 | 0.0777 | 0.0241 | 0.7764 | 0.9281 | 0.0078 | 0.0464 | 0.0056 | 0.0265 | 0.0468 | 0.1126 | 0.1158 | 0.2649 | 0.1815 | 0.2119 | 0.2305 | 0.1854 | 0.1236 | 0.0795 | 0.1336 | 0.0530 | 0.1548 | 0.0199 | 0.0003 | 0.0010 | 0.0075 | 0.0369 | 0.0799 | 0.1438 | 0.1237 | 0.1565 | 0.4503 | 10 | 11 | 13 | 16 | 25 | 62 | 149 | 281 | 445 | 0.1040 | 21.77 | 4.771 | 0.5558 | 55854.0 | 29600000 | 17800000000 | 11700000000000 | 0.5221 | 0.1170 | 0.0474 | 0.0028 | 0.1966 | 0.0109 | 0.3034 | 0.1095 | 0.1798 | 0.1664 | 0.1433 | 0.2227 | 0.0870 | 0.1986 | 0.0267 | 0.1227 | 0.0128 | 0.0858 | 0.0030 | 0.0806 | 0.0003 | 0.0003 | 0.0009 | 0.0003 | 0.0017 | 0.0020 | 0.0094 | 0.0084 | 0.0422 | 0.0385 | 0.0682 | 0.0630 | 0.0444 | 0.0432 | 0.0669 | 0.0635 | 0.7660 | 0.7808 | 0.0002 | 0.0002 | 0.0002 | 0.0009 | 0.0014 | 0.0024 | 0.0088 | 0.0122 | 0.0505 | 0.0500 | 0.0741 | 0.0794 | 0.0549 | 0.0568 | 0.0763 | 0.0835 | 0.7338 | 0.7146 | 0.0005 | 0.0006 | 0.0024 | 0.0080 | 0.0436 | 0.0706 | 0.0510 | 0.0733 | 0.7499 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 718 | 209 | 6919 | 20153 | 439.9 | 83.94 | 59.12 | 60.79 | 328 | 364 | 393 | 418 | 442 | 465 | 486 | 511 | 544 | 0.0555 | 1118 | 1.097 | 116.93 | 36.89 | 1 | 0.0405 | 280 | 0.0010 | 31.34 | 7.121 | 0.1942 | 200514.0 | 94500000 | 45900000000 | 23000000000000 | 0.3868 | 0.2525 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0000 | 0.0112 | 0.0015 | 0.0437 | 0.0118 | 0.0766 | 0.0244 | 0.0951 | 0.0209 | 0.1280 | 0.0268 | 0.6427 | 0.9146 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0013 | 0.0171 | 0.0100 | 0.0281 | 0.0194 | 0.0344 | 0.0128 | 0.0426 | 0.0172 | 0.8730 | 0.9393 | 0.0040 | 0.0086 | 0.0081 | 0.0000 | 0.0424 | 0.0259 | 0.0727 | 0.2586 | 0.1354 | 0.0862 | 0.1687 | 0.1810 | 0.1343 | 0.1293 | 0.1384 | 0.0431 | 0.2960 | 0.2672 | 0.0003 | 0.0014 | 0.0020 | 0.0108 | 0.0519 | 0.0935 | 0.0896 | 0.1278 | 0.6227 | 8 | 10 | 14 | 25 | 40 | 57 | 76 | 99 | 135 | 0.0457 | 4.18 | 4.483 | 0.5799 | 7190.4 | 1330000 | 338000000 | 109000000000 | 0.4299 | 0.1814 | 0.0071 | 0.0015 | 0.0560 | 0.0042 | 0.1504 | 0.0171 | 0.2041 | 0.0543 | 0.2237 | 0.1277 | 0.1653 | 0.2005 | 0.1077 | 0.1668 | 0.0611 | 0.1704 | 0.0247 | 0.2575 | 0.0002 | 0.0001 | 0.0009 | 0.0008 | 0.0023 | 0.0018 | 0.0122 | 0.0087 | 0.0364 | 0.0271 | 0.0609 | 0.0475 | 0.0552 | 0.0389 | 0.0755 | 0.0611 | 0.7565 | 0.8141 | 0.0011 | 0.0011 | 0.0026 | 0.0037 | 0.0041 | 0.0073 | 0.0192 | 0.0257 | 0.0575 | 0.0690 | 0.0847 | 0.1021 | 0.0802 | 0.0802 | 0.1038 | 0.1182 | 0.6468 | 0.5927 | 0.0005 | 0.0010 | 0.0038 | 0.0132 | 0.0444 | 0.0754 | 0.0604 | 0.0891 | 0.7123 | |||
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 407 | 716 | 7114 | 12770 | 534.1 | 94.65 | 61.96 | 146.06 | 380 | 451 | 508 | 534 | 555 | 577 | 594 | 611 | 633 | 0.0662 | 846 | 0.850 | 97.59 | 26.25 | 2 | 0.0417 | 297 | 0.0011 | 32.30 | 7.208 | 0.2276 | 294243.0 | 166000000 | 95600000000 | 55900000000000 | 0.4540 | 0.2027 | 0.0002 | 0.0001 | 0.0009 | 0.0006 | 0.0015 | 0.0003 | 0.0052 | 0.0017 | 0.0232 | 0.0121 | 0.0462 | 0.0176 | 0.0420 | 0.0150 | 0.0641 | 0.0232 | 0.8167 | 0.9294 | 0.0002 | 0.0001 | 0.0003 | 0.0006 | 0.0002 | 0.0003 | 0.0007 | 0.0017 | 0.0128 | 0.0121 | 0.0245 | 0.0176 | 0.0130 | 0.0150 | 0.0239 | 0.0232 | 0.9245 | 0.9294 | 0.0121 | 0.0000 | 0.0208 | 0.0000 | 0.0363 | 0.0000 | 0.0813 | 0.0000 | 0.1142 | 0.0000 | 0.1280 | 0.0000 | 0.1090 | 0.0000 | 0.1228 | 0.0000 | 0.3754 | 0.0000 | 0.0005 | 0.0014 | 0.0054 | 0.0119 | 0.0261 | 0.0428 | 0.0447 | 0.0612 | 0.8061 | 9 | 10 | 11 | 12 | 13 | 15 | 17 | 33 | 165 | 0.1905 | 3.26 | 2.362 | 0.6175 | 25171.9 | 16600000 | 13100000000 | 11600000000000 | 0.6507 | 0.0699 | 0.0193 | 0.0057 | 0.1322 | 0.0086 | 0.2204 | 0.0743 | 0.1736 | 0.1329 | 0.1267 | 0.2157 | 0.0909 | 0.1571 | 0.0716 | 0.0929 | 0.0661 | 0.1114 | 0.0992 | 0.2014 | 0.0000 | 0.0008 | 0.0009 | 0.0008 | 0.0031 | 0.0028 | 0.0098 | 0.0102 | 0.0459 | 0.0468 | 0.0570 | 0.0533 | 0.0459 | 0.0403 | 0.0731 | 0.0744 | 0.7643 | 0.7706 | 0.0011 | 0.0006 | 0.0021 | 0.0017 | 0.0069 | 0.0040 | 0.0133 | 0.0108 | 0.0436 | 0.0483 | 0.0760 | 0.0802 | 0.0452 | 0.0495 | 0.0803 | 0.0870 | 0.7315 | 0.7180 | 0.0005 | 0.0019 | 0.0048 | 0.0150 | 0.0446 | 0.0650 | 0.0509 | 0.0805 | 0.7368 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 658 | 779 | 5169 | 11172 | 137.7 | 32.46 | 113.17 | 91.87 | 100 | 111 | 120 | 127 | 134 | 142 | 150 | 160 | 178 | 0.0719 | 803 | 0.859 | 104.81 | 28.16 | 1 | 0.0530 | 274 | 0.0021 | 21.91 | 6.455 | 0.2447 | 20003.2 | 3080000 | 502000000 | 87100000000 | 0.4380 | 0.2131 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0072 | 0.0000 | 0.0208 | 0.0021 | 0.0760 | 0.0199 | 0.1417 | 0.0475 | 0.1466 | 0.0488 | 0.1981 | 0.0785 | 0.4089 | 0.8031 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0077 | 0.0008 | 0.0363 | 0.0134 | 0.0672 | 0.0294 | 0.0593 | 0.0203 | 0.0997 | 0.0401 | 0.7272 | 0.8959 | 0.0081 | 0.0139 | 0.0185 | 0.0209 | 0.0288 | 0.0453 | 0.0819 | 0.1603 | 0.1453 | 0.1672 | 0.1926 | 0.1812 | 0.1119 | 0.0836 | 0.1407 | 0.1324 | 0.2722 | 0.1951 | 0.0025 | 0.0042 | 0.0148 | 0.0420 | 0.0954 | 0.1238 | 0.1081 | 0.1361 | 0.4731 | 15 | 30 | 49 | 70 | 92 | 118 | 149 | 185 | 238 | 0.0049 | 34.56 | 6.477 | 0.3146 | 21247.0 | 5290000 | 1630000000 | 593000000000 | 0.5230 | 0.1320 | 0.0237 | 0.0013 | 0.1084 | 0.0065 | 0.2323 | 0.0500 | 0.1730 | 0.0940 | 0.1806 | 0.1655 | 0.1412 | 0.2079 | 0.0846 | 0.1542 | 0.0415 | 0.1364 | 0.0146 | 0.1841 | 0.0004 | 0.0003 | 0.0009 | 0.0000 | 0.0057 | 0.0022 | 0.0210 | 0.0114 | 0.0670 | 0.0515 | 0.1169 | 0.0950 | 0.0867 | 0.0772 | 0.1217 | 0.1026 | 0.5799 | 0.6597 | 0.0011 | 0.0007 | 0.0029 | 0.0076 | 0.0111 | 0.0152 | 0.0315 | 0.0444 | 0.0978 | 0.1136 | 0.1574 | 0.1758 | 0.0999 | 0.1242 | 0.1479 | 0.1351 | 0.4505 | 0.3834 | 0.0009 | 0.0021 | 0.0064 | 0.0277 | 0.0813 | 0.1285 | 0.1054 | 0.1321 | 0.5156 | |||
MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 729 | 312 | 7306 | 11974 | 613.3 | 129.28 | 138.56 | 260.97 | 460 | 513 | 546 | 576 | 604 | 631 | 663 | 705 | 779 | 0.0833 | 997 | 1.173 | 110.11 | 34.67 | 1 | 0.0356 | 260 | 0.0006 | 91.47 | 7.747 | 0.1387 | 392795.0 | 263000000 | 183000000000 | 133000000000000 | 0.4412 | 0.2054 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0004 | 0.0084 | 0.0022 | 0.0416 | 0.0166 | 0.0910 | 0.0363 | 0.1054 | 0.0298 | 0.1371 | 0.0406 | 0.6140 | 0.8741 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0004 | 0.0024 | 0.0010 | 0.0180 | 0.0122 | 0.0418 | 0.0199 | 0.0422 | 0.0119 | 0.0634 | 0.0208 | 0.8310 | 0.9338 | 0.0046 | 0.0000 | 0.0092 | 0.0029 | 0.0295 | 0.0146 | 0.0867 | 0.1108 | 0.0941 | 0.1837 | 0.1614 | 0.2157 | 0.1144 | 0.1224 | 0.1153 | 0.1079 | 0.3847 | 0.2420 | 0.0015 | 0.0056 | 0.0082 | 0.0316 | 0.0647 | 0.1109 | 0.0989 | 0.1229 | 0.5559 | 6 | 8 | 9 | 13 | 22 | 47 | 98 | 198 | 434 | 0.0993 | 31.78 | 4.313 | 0.5808 | 87298.6 | 89300000 | 118000000000 | 185000000000000 | 0.4711 | 0.1719 | 0.0442 | 0.0014 | 0.1509 | 0.0196 | 0.2302 | 0.0825 | 0.2088 | 0.0965 | 0.1814 | 0.1972 | 0.0838 | 0.1930 | 0.0427 | 0.1343 | 0.0381 | 0.1273 | 0.0198 | 0.1483 | 0.0003 | 0.0005 | 0.0009 | 0.0005 | 0.0009 | 0.0018 | 0.0089 | 0.0096 | 0.0546 | 0.0480 | 0.1005 | 0.0828 | 0.0650 | 0.0568 | 0.0942 | 0.0835 | 0.6747 | 0.7164 | 0.0004 | 0.0004 | 0.0004 | 0.0012 | 0.0022 | 0.0008 | 0.0115 | 0.0144 | 0.0749 | 0.0804 | 0.1197 | 0.1267 | 0.0782 | 0.0776 | 0.1019 | 0.1110 | 0.6108 | 0.5875 | 0.0000 | 0.0003 | 0.0013 | 0.0127 | 0.0586 | 0.1195 | 0.0696 | 0.0917 | 0.6463 |