High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 422 | 387 | | 8367 | 21686 | 338.6 | 51.23 | 216.62 | 253.93 | 275 | 292 | 307 | 321 | 337 | 351 | 367 | 383 | 406 | 0.0592 | 1284 | 1.224 | 118.07 | 44.69 | 1 | 0.0354 | 296 | 0.0016 | 21.25 | 6.715 | 0.2518 | 117279.0 | 41500000 | 15000000000 | 5540000000000 | 0.4429 | 0.2078 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0080 | 0.0001 | 0.0305 | 0.0112 | 0.0543 | 0.0192 | 0.0664 | 0.0146 | 0.1150 | 0.0208 | 0.7238 | 0.9341 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0034 | 0.0000 | 0.0155 | 0.0105 | 0.0264 | 0.0169 | 0.0305 | 0.0096 | 0.0535 | 0.0147 | 0.8698 | 0.9484 | 0.0147 | 0.0000 | 0.0209 | 0.0000 | 0.0466 | 0.0000 | 0.0798 | 0.0000 | 0.1325 | 0.0000 | 0.1509 | 0.0000 | 0.1166 | 0.0000 | 0.1387 | 0.0000 | 0.2994 | 0.0000 | 0.0029 | 0.0037 | 0.0079 | 0.0179 | 0.0489 | 0.0872 | 0.0769 | 0.1138 | 0.6407 | 23 | 31 | 44 | 65 | 97 | 158 | 256 | 389 | 599 | 0.0168 | 30.30 | 6.006 | 0.4494 | 111401.0 | 80200000 | 68700000000 | 66100000000000 | 0.5043 | 0.1472 | 0.0237 | 0.0026 | 0.1369 | 0.0072 | 0.2565 | 0.0574 | 0.1751 | 0.1186 | 0.1568 | 0.1945 | 0.1196 | 0.2092 | 0.0501 | 0.1261 | 0.0356 | 0.1132 | 0.0458 | 0.1711 | 0.0002 | 0.0003 | 0.0005 | 0.0006 | 0.0022 | 0.0014 | 0.0105 | 0.0091 | 0.0514 | 0.0447 | 0.0911 | 0.0790 | 0.0565 | 0.0498 | 0.0825 | 0.0754 | 0.7050 | 0.7396 | 0.0003 | 0.0002 | 0.0011 | 0.0016 | 0.0023 | 0.0053 | 0.0156 | 0.0192 | 0.0627 | 0.0685 | 0.1061 | 0.1174 | 0.0749 | 0.0819 | 0.0955 | 0.0997 | 0.6414 | 0.6062 | 0.0001 | 0.0003 | 0.0026 | 0.0142 | 0.0598 | 0.0932 | 0.0668 | 0.0874 | 0.6756 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 921 | 862 | | 6477 | 15065 | 403.9 | 109.37 | 121.63 | 165.75 | 277 | 309 | 337 | 363 | 389 | 418 | 449 | 490 | 551 | 0.0525 | 791 | 0.968 | 109.17 | 33.06 | 1 | 0.0426 | 276 | 0.0006 | 77.54 | 7.589 | 0.1419 | 175073.0 | 81300000 | 40400000000 | 21300000000000 | 0.4463 | 0.2101 | 0.0000 | 0.0000 | 0.0023 | 0.0000 | 0.0155 | 0.0004 | 0.0348 | 0.0028 | 0.1035 | 0.0244 | 0.1860 | 0.0559 | 0.1699 | 0.0627 | 0.1719 | 0.0842 | 0.3162 | 0.7696 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0023 | 0.0002 | 0.0093 | 0.0018 | 0.0399 | 0.0117 | 0.0837 | 0.0302 | 0.0747 | 0.0280 | 0.0983 | 0.0411 | 0.6910 | 0.8871 | 0.0029 | 0.0053 | 0.0174 | 0.0106 | 0.0101 | 0.0301 | 0.0702 | 0.0816 | 0.1259 | 0.1667 | 0.1802 | 0.1613 | 0.0948 | 0.1241 | 0.1324 | 0.1436 | 0.3661 | 0.2766 | 0.0003 | 0.0010 | 0.0055 | 0.0331 | 0.0776 | 0.1479 | 0.1117 | 0.1317 | 0.4912 | 7 | 9 | 13 | 25 | 47 | 84 | 137 | 215 | 339 | 0.0659 | 15.12 | 4.966 | 0.5541 | 42265.8 | 22000000 | 14400000000 | 10800000000000 | 0.3883 | 0.2650 | 0.0173 | 0.0015 | 0.0965 | 0.0090 | 0.2033 | 0.0324 | 0.1790 | 0.0799 | 0.1931 | 0.1735 | 0.1468 | 0.2123 | 0.0950 | 0.1508 | 0.0502 | 0.1388 | 0.0188 | 0.2017 | 0.0002 | 0.0002 | 0.0013 | 0.0011 | 0.0020 | 0.0012 | 0.0089 | 0.0089 | 0.0379 | 0.0318 | 0.0609 | 0.0533 | 0.0508 | 0.0440 | 0.0713 | 0.0640 | 0.7668 | 0.7956 | 0.0000 | 0.0003 | 0.0007 | 0.0005 | 0.0044 | 0.0032 | 0.0125 | 0.0119 | 0.0504 | 0.0631 | 0.0900 | 0.0998 | 0.0666 | 0.0700 | 0.0928 | 0.1054 | 0.6826 | 0.6458 | 0.0002 | 0.0002 | 0.0026 | 0.0098 | 0.0427 | 0.0786 | 0.0642 | 0.0823 | 0.7195 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 849 | | 5669 | 11631 | 149.6 | 30.26 | 380.14 | 292.12 | 115 | 126 | 133 | 140 | 146 | 153 | 161 | 172 | 189 | 0.0978 | 1138 | 0.853 | 87.32 | 20.22 | 4 | 0.0376 | 213 | 0.0246 | 2.00 | 4.135 | 0.5882 | 23308.7 | 3780000 | 639000000 | 113000000000 | 0.4512 | 0.2143 | 0.0005 | 0.0000 | 0.0019 | 0.0004 | 0.0066 | 0.0006 | 0.0209 | 0.0047 | 0.0542 | 0.0190 | 0.1074 | 0.0594 | 0.1031 | 0.0456 | 0.1449 | 0.0760 | 0.5605 | 0.7945 | 0.0002 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0005 | 0.0087 | 0.0041 | 0.0281 | 0.0148 | 0.0485 | 0.0422 | 0.0396 | 0.0185 | 0.0686 | 0.0351 | 0.8028 | 0.8846 | 0.0072 | 0.0165 | 0.0217 | 0.0535 | 0.0253 | 0.0535 | 0.0939 | 0.1934 | 0.1721 | 0.2058 | 0.1877 | 0.1934 | 0.1095 | 0.0864 | 0.1300 | 0.0947 | 0.2527 | 0.1029 | 0.0031 | 0.0043 | 0.0152 | 0.0390 | 0.0928 | 0.1383 | 0.1200 | 0.1380 | 0.4493 | 68 | 117 | 173 | 239 | 313 | 389 | 493 | 610 | 797 | 0.0026 | 36.91 | 6.778 | 0.2991 | 229829.0 | 180000000 | 166000000000 | 173000000000000 | 0.5041 | 0.1494 | 0.0174 | 0.0017 | 0.0886 | 0.0073 | 0.1781 | 0.0403 | 0.1658 | 0.0825 | 0.1856 | 0.1556 | 0.1451 | 0.1874 | 0.0933 | 0.1449 | 0.0612 | 0.1473 | 0.0650 | 0.2330 | 0.0002 | 0.0000 | 0.0023 | 0.0006 | 0.0058 | 0.0035 | 0.0167 | 0.0122 | 0.0657 | 0.0480 | 0.1189 | 0.0967 | 0.0796 | 0.0703 | 0.1194 | 0.1013 | 0.5913 | 0.6674 | 0.0015 | 0.0013 | 0.0036 | 0.0039 | 0.0103 | 0.0186 | 0.0328 | 0.0417 | 0.0904 | 0.1037 | 0.1420 | 0.1637 | 0.1030 | 0.1027 | 0.1258 | 0.1376 | 0.4904 | 0.4266 | 0.0006 | 0.0031 | 0.0121 | 0.0249 | 0.0804 | 0.1317 | 0.0936 | 0.1214 | 0.5321 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 367 | 527 | | 14166 | 30978 | 166.3 | 51.48 | 150.74 | 180.13 | 108 | 123 | 136 | 147 | 158 | 171 | 186 | 207 | 241 | 0.0455 | 1410 | 1.186 | 107.56 | 39.85 | 4 | 0.0193 | 274 | 0.0029 | 11.78 | 6.212 | 0.3232 | 30318.4 | 6020000 | 1290000000 | 298000000000 | 0.4567 | 0.2012 | 0.0010 | 0.0002 | 0.0020 | 0.0003 | 0.0095 | 0.0011 | 0.0293 | 0.0063 | 0.0939 | 0.0301 | 0.1627 | 0.0648 | 0.1523 | 0.0591 | 0.1747 | 0.0901 | 0.3747 | 0.7480 | 0.0004 | 0.0000 | 0.0004 | 0.0001 | 0.0027 | 0.0002 | 0.0099 | 0.0021 | 0.0378 | 0.0155 | 0.0638 | 0.0296 | 0.0626 | 0.0267 | 0.0911 | 0.0439 | 0.7313 | 0.8820 | 0.0021 | 0.0018 | 0.0049 | 0.0083 | 0.0147 | 0.0155 | 0.0350 | 0.0596 | 0.0936 | 0.1173 | 0.1393 | 0.1757 | 0.0967 | 0.1203 | 0.1362 | 0.1471 | 0.4774 | 0.3544 | 0.0008 | 0.0034 | 0.0088 | 0.0319 | 0.0709 | 0.1074 | 0.0856 | 0.1046 | 0.5866 | 8 | 10 | 15 | 33 | 75 | 129 | 195 | 283 | 413 | 0.0651 | 14.33 | 5.012 | 0.4997 | 55169.9 | 27400000 | 16300000000 | 11100000000000 | 0.5068 | 0.1638 | 0.0376 | 0.0026 | 0.1800 | 0.0101 | 0.2471 | 0.0930 | 0.1592 | 0.1413 | 0.1404 | 0.1940 | 0.1108 | 0.1938 | 0.0625 | 0.1310 | 0.0393 | 0.1131 | 0.0232 | 0.1211 | 0.0002 | 0.0002 | 0.0005 | 0.0001 | 0.0016 | 0.0012 | 0.0097 | 0.0069 | 0.0522 | 0.0426 | 0.0886 | 0.0730 | 0.0686 | 0.0557 | 0.1054 | 0.0879 | 0.6732 | 0.7326 | 0.0004 | 0.0006 | 0.0015 | 0.0020 | 0.0027 | 0.0051 | 0.0177 | 0.0220 | 0.0740 | 0.0904 | 0.1206 | 0.1278 | 0.0882 | 0.0952 | 0.1271 | 0.1330 | 0.5678 | 0.5239 | 0.0000 | 0.0020 | 0.0028 | 0.0144 | 0.0620 | 0.1077 | 0.0815 | 0.1152 | 0.6146 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1035 | 628 | | 3458 | 8206 | 93.8 | 23.90 | 164.82 | 119.42 | 66 | 74 | 79 | 85 | 91 | 97 | 104 | 113 | 127 | 0.1078 | 885 | 0.355 | 97.08 | 18.11 | 4 | 0.0992 | 343 | 0.0017 | 31.62 | 6.627 | 0.2197 | 9369.6 | 995442 | 112000000 | 13400000000 | 0.5072 | 0.1581 | 0.0015 | 0.0000 | 0.0041 | 0.0003 | 0.0193 | 0.0026 | 0.0491 | 0.0078 | 0.1120 | 0.0342 | 0.1621 | 0.0785 | 0.1682 | 0.0691 | 0.1778 | 0.1092 | 0.3060 | 0.6983 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0049 | 0.0006 | 0.0154 | 0.0030 | 0.0566 | 0.0245 | 0.0779 | 0.0558 | 0.0738 | 0.0349 | 0.1124 | 0.0626 | 0.6576 | 0.8187 | 0.0000 | 0.0233 | 0.0158 | 0.0117 | 0.0288 | 0.0623 | 0.0806 | 0.1440 | 0.1568 | 0.1673 | 0.1683 | 0.1479 | 0.1094 | 0.1012 | 0.1540 | 0.1206 | 0.2863 | 0.2218 | 0.0013 | 0.0064 | 0.0160 | 0.0415 | 0.0958 | 0.1213 | 0.1232 | 0.1430 | 0.4515 | 25 | 62 | 87 | 112 | 142 | 175 | 210 | 257 | 327 | 0.0060 | 20.13 | 5.985 | 0.3796 | 41426.6 | 13400000 | 5300000000 | 2470000000000 | 0.5023 | 0.1523 | 0.0128 | 0.0015 | 0.0745 | 0.0055 | 0.1680 | 0.0312 | 0.1607 | 0.0802 | 0.1796 | 0.1311 | 0.1362 | 0.1697 | 0.1057 | 0.1489 | 0.0910 | 0.1507 | 0.0715 | 0.2812 | 0.0002 | 0.0004 | 0.0002 | 0.0017 | 0.0048 | 0.0030 | 0.0166 | 0.0153 | 0.0547 | 0.0413 | 0.1021 | 0.0745 | 0.0780 | 0.0668 | 0.1117 | 0.0947 | 0.6316 | 0.7023 | 0.0011 | 0.0014 | 0.0047 | 0.0048 | 0.0131 | 0.0106 | 0.0367 | 0.0476 | 0.0956 | 0.1264 | 0.1425 | 0.1563 | 0.1142 | 0.1317 | 0.1455 | 0.1582 | 0.4465 | 0.3630 | 0.0000 | 0.0011 | 0.0056 | 0.0240 | 0.0760 | 0.1185 | 0.0978 | 0.1440 | 0.5328 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 429 | 152 | | 5147 | 13190 | 300.5 | 77.17 | 108.66 | 110.80 | 212 | 234 | 254 | 271 | 289 | 308 | 329 | 359 | 403 | 0.0728 | 960 | 0.674 | 104.17 | 19.70 | 1 | 0.0492 | 253 | 0.0006 | 94.37 | 7.666 | 0.1240 | 96226.5 | 32900000 | 12000000000 | 4710000000000 | 0.3982 | 0.2452 | 0.0017 | 0.0000 | 0.0014 | 0.0000 | 0.0024 | 0.0000 | 0.0279 | 0.0028 | 0.0927 | 0.0245 | 0.1714 | 0.0507 | 0.1714 | 0.0507 | 0.1830 | 0.0752 | 0.3480 | 0.7962 | 0.0013 | 0.0000 | 0.0005 | 0.0000 | 0.0018 | 0.0000 | 0.0109 | 0.0012 | 0.0344 | 0.0148 | 0.0725 | 0.0281 | 0.0803 | 0.0224 | 0.0990 | 0.0368 | 0.6993 | 0.8967 | 0.0020 | 0.0026 | 0.0107 | 0.0104 | 0.0176 | 0.0260 | 0.0547 | 0.0935 | 0.1270 | 0.1636 | 0.1680 | 0.1896 | 0.1240 | 0.1221 | 0.1416 | 0.1377 | 0.3545 | 0.2545 | 0.0004 | 0.0031 | 0.0118 | 0.0298 | 0.0815 | 0.1333 | 0.1109 | 0.1337 | 0.4954 | 12 | 16 | 22 | 38 | 65 | 103 | 146 | 200 | 271 | 0.0288 | 11.68 | 5.216 | 0.4837 | 24083.1 | 7070000 | 2440000000 | 950000000000 | 0.4467 | 0.1953 | 0.0280 | 0.0011 | 0.1405 | 0.0047 | 0.2943 | 0.0614 | 0.1729 | 0.1210 | 0.1545 | 0.2201 | 0.0890 | 0.2000 | 0.0655 | 0.1325 | 0.0361 | 0.1174 | 0.0191 | 0.1418 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0011 | 0.0117 | 0.0076 | 0.0534 | 0.0462 | 0.0876 | 0.0766 | 0.0602 | 0.0517 | 0.0834 | 0.0797 | 0.7018 | 0.7371 | 0.0014 | 0.0008 | 0.0016 | 0.0011 | 0.0036 | 0.0074 | 0.0216 | 0.0198 | 0.0664 | 0.0805 | 0.1074 | 0.1116 | 0.0767 | 0.0818 | 0.1035 | 0.1076 | 0.6178 | 0.5896 | 0.0002 | 0.0006 | 0.0020 | 0.0129 | 0.0649 | 0.0943 | 0.0672 | 0.0976 | 0.6603 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 84 | 350 | | 635 | 11961 | 63.2 | 10.04 | 161.70 | 197.63 | 50 | 54 | 57 | 61 | 63 | 66 | 68 | 71 | 76 | 0.0579 | 693 | 0.875 | 142.76 | 45.97 | 2 | 0.6299 | 400 | 0.0068 | 11.22 | 5.192 | 0.3174 | 4092.7 | 271580 | 18400000 | 1280000000 | 0.4246 | 0.2192 | 0.0020 | 0.0000 | 0.0061 | 0.0016 | 0.0242 | 0.0048 | 0.0364 | 0.0111 | 0.0667 | 0.0430 | 0.1091 | 0.0685 | 0.1172 | 0.0525 | 0.1960 | 0.0812 | 0.4424 | 0.7373 | 0.0018 | 0.0000 | 0.0053 | 0.0016 | 0.0124 | 0.0047 | 0.0284 | 0.0110 | 0.0443 | 0.0379 | 0.0585 | 0.0694 | 0.0709 | 0.0394 | 0.0816 | 0.0599 | 0.6968 | 0.7760 | 0.0580 | 0.3333 | 0.0870 | 0.0000 | 0.1594 | 0.3333 | 0.0725 | 0.3333 | 0.1739 | 0.0000 | 0.0870 | 0.0000 | 0.0580 | 0.0000 | 0.1014 | 0.0000 | 0.2029 | 0.0000 | 0.0060 | 0.0030 | 0.0328 | 0.0448 | 0.0836 | 0.1045 | 0.1104 | 0.1761 | 0.4388 | 14 | 18 | 22 | 31 | 58 | 116 | 205 | 315 | 458 | 0.0352 | 28.43 | 5.403 | 0.4619 | 65200.6 | 35400000 | 22500000000 | 16100000000000 | 0.5927 | 0.1032 | 0.1018 | 0.0034 | 0.2284 | 0.0353 | 0.3243 | 0.1826 | 0.1467 | 0.1894 | 0.1089 | 0.2031 | 0.0462 | 0.1570 | 0.0249 | 0.0990 | 0.0130 | 0.0728 | 0.0059 | 0.0575 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0020 | 0.0022 | 0.0142 | 0.0124 | 0.0583 | 0.0519 | 0.0965 | 0.0944 | 0.0720 | 0.0609 | 0.0991 | 0.0924 | 0.6569 | 0.6855 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0029 | 0.0060 | 0.0195 | 0.0279 | 0.0776 | 0.0835 | 0.1193 | 0.1370 | 0.0921 | 0.0943 | 0.1271 | 0.1346 | 0.5598 | 0.5161 | 0.0002 | 0.0002 | 0.0027 | 0.0176 | 0.0677 | 0.1015 | 0.0832 | 0.1135 | 0.6134 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 582 | 250 | | 4778 | 14966 | 457.7 | 96.53 | 89.22 | 140.57 | 342 | 375 | 399 | 423 | 446 | 472 | 503 | 544 | 595 | 0.0565 | 845 | 1.104 | 103.97 | 26.91 | 1 | 0.0479 | 229 | 0.0010 | 47.20 | 7.130 | 0.1892 | 218847.0 | 109000000 | 56500000000 | 30300000000000 | 0.4000 | 0.2511 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0045 | 0.0004 | 0.0175 | 0.0009 | 0.0684 | 0.0206 | 0.1267 | 0.0402 | 0.1305 | 0.0356 | 0.1626 | 0.0566 | 0.4879 | 0.8457 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0048 | 0.0004 | 0.0342 | 0.0151 | 0.0585 | 0.0274 | 0.0650 | 0.0193 | 0.0849 | 0.0278 | 0.7521 | 0.9101 | 0.0078 | 0.0314 | 0.0045 | 0.0314 | 0.0201 | 0.0419 | 0.0536 | 0.0576 | 0.1095 | 0.2042 | 0.1430 | 0.1937 | 0.1128 | 0.1152 | 0.1296 | 0.1571 | 0.4190 | 0.1675 | 0.0018 | 0.0041 | 0.0115 | 0.0290 | 0.0809 | 0.1241 | 0.0938 | 0.1159 | 0.5389 | 5 | 7 | 8 | 10 | 12 | 21 | 71 | 181 | 309 | 0.1594 | 14.47 | 4.050 | 0.6108 | 27717.5 | 11400000 | 5320000000 | 2730000000000 | 0.4192 | 0.2070 | 0.0600 | 0.0054 | 0.1989 | 0.0109 | 0.2420 | 0.0827 | 0.1839 | 0.1544 | 0.1407 | 0.2452 | 0.0882 | 0.1962 | 0.0563 | 0.0990 | 0.0169 | 0.0990 | 0.0131 | 0.1072 | 0.0002 | 0.0002 | 0.0007 | 0.0002 | 0.0009 | 0.0008 | 0.0083 | 0.0087 | 0.0333 | 0.0322 | 0.0492 | 0.0453 | 0.0395 | 0.0316 | 0.0572 | 0.0465 | 0.8108 | 0.8345 | 0.0000 | 0.0005 | 0.0018 | 0.0005 | 0.0025 | 0.0013 | 0.0079 | 0.0070 | 0.0370 | 0.0436 | 0.0631 | 0.0662 | 0.0484 | 0.0554 | 0.0667 | 0.0759 | 0.7725 | 0.7495 | 0.0000 | 0.0000 | 0.0019 | 0.0086 | 0.0378 | 0.0557 | 0.0431 | 0.0633 | 0.7896 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 153 | 139 | | 5758 | 11802 | 360.4 | 40.57 | 302.04 | 287.41 | 307 | 326 | 339 | 350 | 361 | 372 | 383 | 396 | 412 | 0.0835 | 986 | 0.859 | 110.32 | 27.29 | 1 | 0.0455 | 262 | 0.0019 | 22.05 | 6.508 | 0.2365 | 131562.0 | 48600000 | 18200000000 | 6860000000000 | 0.4593 | 0.1900 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0011 | 0.0000 | 0.0030 | 0.0002 | 0.0199 | 0.0116 | 0.0345 | 0.0200 | 0.0450 | 0.0106 | 0.0849 | 0.0181 | 0.8109 | 0.9396 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0002 | 0.0165 | 0.0116 | 0.0244 | 0.0200 | 0.0244 | 0.0106 | 0.0400 | 0.0181 | 0.8916 | 0.9396 | 0.0419 | 0.0000 | 0.1204 | 0.0000 | 0.1414 | 0.0000 | 0.1204 | 0.0000 | 0.0942 | 0.0000 | 0.1204 | 0.0000 | 0.1099 | 0.0000 | 0.1099 | 0.0000 | 0.1414 | 0.0000 | 0.0027 | 0.0030 | 0.0172 | 0.0320 | 0.0573 | 0.1004 | 0.1018 | 0.1375 | 0.5480 | 23 | 35 | 59 | 111 | 207 | 327 | 442 | 575 | 737 | 0.0095 | 68.30 | 6.730 | 0.3226 | 173824.0 | 123000000 | 98700000000 | 86100000000000 | 0.4300 | 0.1996 | 0.0309 | 0.0016 | 0.1561 | 0.0094 | 0.2346 | 0.0661 | 0.1920 | 0.1351 | 0.1669 | 0.2033 | 0.1068 | 0.2090 | 0.0576 | 0.1286 | 0.0434 | 0.1167 | 0.0117 | 0.1302 | 0.0002 | 0.0000 | 0.0004 | 0.0002 | 0.0011 | 0.0013 | 0.0078 | 0.0063 | 0.0446 | 0.0401 | 0.0822 | 0.0683 | 0.0522 | 0.0435 | 0.0816 | 0.0691 | 0.7299 | 0.7711 | 0.0005 | 0.0003 | 0.0007 | 0.0019 | 0.0032 | 0.0051 | 0.0178 | 0.0177 | 0.0597 | 0.0756 | 0.1097 | 0.1293 | 0.0834 | 0.0942 | 0.1134 | 0.1322 | 0.6116 | 0.5437 | 0.0000 | 0.0002 | 0.0008 | 0.0107 | 0.0530 | 0.0945 | 0.0643 | 0.1014 | 0.6751 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 179 | 861 | | 6894 | 24993 | 432.7 | 77.04 | 123.09 | 229.52 | 337 | 363 | 385 | 406 | 427 | 448 | 470 | 497 | 536 | 0.0541 | 1352 | 1.247 | 106.10 | 42.20 | 2 | 0.0392 | 270 | 0.0024 | 14.62 | 6.292 | 0.2830 | 193164.0 | 88900000 | 42200000000 | 20600000000000 | 0.4573 | 0.1908 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0034 | 0.0000 | 0.0121 | 0.0006 | 0.0472 | 0.0149 | 0.0960 | 0.0253 | 0.1212 | 0.0267 | 0.1545 | 0.0354 | 0.5647 | 0.8972 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0065 | 0.0001 | 0.0253 | 0.0121 | 0.0467 | 0.0177 | 0.0549 | 0.0126 | 0.0783 | 0.0167 | 0.7863 | 0.9408 | 0.0053 | 0.0000 | 0.0160 | 0.0701 | 0.0299 | 0.0764 | 0.0812 | 0.1783 | 0.1335 | 0.1720 | 0.1656 | 0.1783 | 0.1186 | 0.1274 | 0.1346 | 0.0955 | 0.3152 | 0.1019 | 0.0009 | 0.0037 | 0.0079 | 0.0244 | 0.0711 | 0.1200 | 0.1053 | 0.1236 | 0.5430 | 8 | 10 | 12 | 13 | 16 | 23 | 63 | 188 | 422 | 0.2078 | 29.75 | 3.972 | 0.6370 | 67827.8 | 55500000 | 55600000000 | 63900000000000 | 0.4521 | 0.1694 | 0.1333 | 0.0042 | 0.3651 | 0.0371 | 0.3035 | 0.2123 | 0.1120 | 0.2751 | 0.0504 | 0.2537 | 0.0202 | 0.1124 | 0.0090 | 0.0570 | 0.0045 | 0.0314 | 0.0022 | 0.0167 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0014 | 0.0008 | 0.0135 | 0.0108 | 0.0527 | 0.0490 | 0.0825 | 0.0789 | 0.0578 | 0.0500 | 0.0808 | 0.0738 | 0.7110 | 0.7365 | 0.0002 | 0.0004 | 0.0009 | 0.0010 | 0.0018 | 0.0029 | 0.0147 | 0.0130 | 0.0575 | 0.0617 | 0.0963 | 0.1072 | 0.0686 | 0.0675 | 0.0945 | 0.1032 | 0.6655 | 0.6432 | 0.0007 | 0.0005 | 0.0013 | 0.0119 | 0.0549 | 0.0931 | 0.0549 | 0.0860 | 0.6968 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 615 | 87 | | 3644 | 13644 | 486.1 | 117.15 | 117.91 | 188.35 | 319 | 379 | 428 | 463 | 490 | 516 | 545 | 579 | 629 | 0.0704 | 960 | 0.778 | 78.75 | 25.08 | 2 | 0.0645 | 235 | 0.0008 | 59.20 | 7.366 | 0.1629 | 250045.0 | 135000000 | 76400000000 | 45000000000000 | 0.3808 | 0.2634 | 0.0005 | 0.0003 | 0.0023 | 0.0006 | 0.0065 | 0.0012 | 0.0208 | 0.0024 | 0.0644 | 0.0260 | 0.1185 | 0.0474 | 0.1181 | 0.0477 | 0.1537 | 0.0608 | 0.5153 | 0.8136 | 0.0004 | 0.0003 | 0.0004 | 0.0006 | 0.0025 | 0.0009 | 0.0053 | 0.0017 | 0.0246 | 0.0206 | 0.0421 | 0.0342 | 0.0333 | 0.0284 | 0.0512 | 0.0353 | 0.8404 | 0.8781 | 0.0029 | 0.0165 | 0.0072 | 0.0110 | 0.0435 | 0.0165 | 0.0609 | 0.0824 | 0.1493 | 0.1319 | 0.1493 | 0.1648 | 0.1232 | 0.1044 | 0.1130 | 0.1154 | 0.3507 | 0.3571 | 0.0011 | 0.0005 | 0.0037 | 0.0186 | 0.0541 | 0.0981 | 0.1140 | 0.1352 | 0.5748 | 5 | 7 | 9 | 12 | 18 | 41 | 105 | 209 | 414 | 0.0925 | 12.28 | 4.224 | 0.5614 | 49376.8 | 28700000 | 20000000000 | 16200000000000 | 0.4378 | 0.2206 | 0.0432 | 0.0012 | 0.1512 | 0.0148 | 0.2160 | 0.0598 | 0.1677 | 0.1006 | 0.1423 | 0.1764 | 0.1017 | 0.1795 | 0.0839 | 0.1388 | 0.0597 | 0.1184 | 0.0343 | 0.2104 | 0.0002 | 0.0000 | 0.0007 | 0.0011 | 0.0035 | 0.0013 | 0.0091 | 0.0065 | 0.0424 | 0.0378 | 0.0666 | 0.0551 | 0.0544 | 0.0477 | 0.0811 | 0.0656 | 0.7419 | 0.7849 | 0.0006 | 0.0006 | 0.0023 | 0.0029 | 0.0046 | 0.0048 | 0.0126 | 0.0140 | 0.0584 | 0.0619 | 0.0822 | 0.0909 | 0.0664 | 0.0635 | 0.0908 | 0.0804 | 0.6821 | 0.6810 | 0.0000 | 0.0018 | 0.0028 | 0.0106 | 0.0536 | 0.0732 | 0.0590 | 0.0912 | 0.7077 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 504 | 454 | | 4632 | 9949 | 526.7 | 103.94 | 144.23 | 161.03 | 403 | 434 | 461 | 488 | 517 | 541 | 573 | 613 | 674 | 0.0767 | 763 | 1.167 | 101.13 | 34.54 | 1 | 0.0531 | 246 | 0.0009 | 55.30 | 7.231 | 0.1624 | 288245.0 | 164000000 | 96700000000 | 59100000000000 | 0.4365 | 0.2052 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0095 | 0.0004 | 0.0653 | 0.0181 | 0.1242 | 0.0349 | 0.1378 | 0.0329 | 0.1714 | 0.0511 | 0.4897 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0044 | 0.0002 | 0.0279 | 0.0136 | 0.0541 | 0.0242 | 0.0597 | 0.0141 | 0.0859 | 0.0249 | 0.7668 | 0.9230 | 0.0054 | 0.0188 | 0.0054 | 0.0125 | 0.0201 | 0.0313 | 0.0698 | 0.1438 | 0.1557 | 0.2438 | 0.1906 | 0.1750 | 0.1302 | 0.1188 | 0.1664 | 0.1563 | 0.2564 | 0.1000 | 0.0009 | 0.0038 | 0.0033 | 0.0302 | 0.0797 | 0.1282 | 0.1249 | 0.1556 | 0.4734 | 18 | 28 | 46 | 67 | 93 | 124 | 163 | 220 | 330 | 0.0156 | 19.65 | 5.459 | 0.4608 | 46729.0 | 24700000 | 17300000000 | 14400000000000 | 0.5530 | 0.1302 | 0.0176 | 0.0010 | 0.1067 | 0.0100 | 0.2360 | 0.0424 | 0.1854 | 0.0883 | 0.1601 | 0.1621 | 0.1292 | 0.2014 | 0.0730 | 0.1717 | 0.0597 | 0.1438 | 0.0323 | 0.1793 | 0.0002 | 0.0000 | 0.0009 | 0.0012 | 0.0024 | 0.0019 | 0.0176 | 0.0129 | 0.0691 | 0.0574 | 0.1203 | 0.0945 | 0.0888 | 0.0781 | 0.1108 | 0.1107 | 0.5899 | 0.6432 | 0.0004 | 0.0009 | 0.0011 | 0.0022 | 0.0061 | 0.0106 | 0.0301 | 0.0396 | 0.1050 | 0.1091 | 0.1384 | 0.1552 | 0.0986 | 0.0994 | 0.1376 | 0.1271 | 0.4828 | 0.4560 | 0.0017 | 0.0012 | 0.0043 | 0.0240 | 0.0822 | 0.1343 | 0.0909 | 0.1308 | 0.5305 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 603 | 689 | | 7600 | 15811 | 210.9 | 43.78 | 142.17 | 171.25 | 159 | 173 | 185 | 196 | 207 | 218 | 230 | 245 | 269 | 0.0623 | 985 | 1.140 | 88.32 | 39.01 | 1 | 0.0330 | 251 | 0.0011 | 39.63 | 7.083 | 0.1887 | 46382.0 | 10600000 | 2540000000 | 632000000000 | 0.4649 | 0.1876 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0031 | 0.0000 | 0.0156 | 0.0013 | 0.0581 | 0.0167 | 0.1363 | 0.0365 | 0.1516 | 0.0327 | 0.1761 | 0.0584 | 0.4584 | 0.8545 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0074 | 0.0004 | 0.0307 | 0.0110 | 0.0643 | 0.0228 | 0.0646 | 0.0137 | 0.0939 | 0.0247 | 0.7375 | 0.9274 | 0.0050 | 0.0238 | 0.0058 | 0.0149 | 0.0284 | 0.0387 | 0.0984 | 0.1310 | 0.1418 | 0.1786 | 0.1818 | 0.1994 | 0.0992 | 0.1012 | 0.1276 | 0.1250 | 0.3119 | 0.1875 | 0.0009 | 0.0020 | 0.0111 | 0.0386 | 0.0873 | 0.1384 | 0.1199 | 0.1335 | 0.4684 | 11 | 13 | 15 | 21 | 53 | 120 | 192 | 279 | 392 | 0.0646 | 26.36 | 5.217 | 0.4922 | 49534.8 | 23000000 | 12600000000 | 7870000000000 | 0.5544 | 0.1062 | 0.0575 | 0.0021 | 0.2553 | 0.0185 | 0.3274 | 0.1627 | 0.1596 | 0.1906 | 0.0883 | 0.1964 | 0.0624 | 0.1886 | 0.0300 | 0.1011 | 0.0130 | 0.0719 | 0.0065 | 0.0682 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0005 | 0.0010 | 0.0079 | 0.0052 | 0.0517 | 0.0451 | 0.0963 | 0.0833 | 0.0703 | 0.0593 | 0.0991 | 0.0835 | 0.6739 | 0.7223 | 0.0002 | 0.0004 | 0.0013 | 0.0015 | 0.0029 | 0.0043 | 0.0140 | 0.0201 | 0.0689 | 0.0788 | 0.1235 | 0.1391 | 0.0936 | 0.0936 | 0.1214 | 0.1176 | 0.5743 | 0.5445 | 0.0000 | 0.0003 | 0.0017 | 0.0095 | 0.0610 | 0.1104 | 0.0758 | 0.1149 | 0.6263 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 156 | 594 | | 9080 | 15618 | 311.0 | 68.29 | 98.46 | 121.64 | 229 | 251 | 270 | 288 | 305 | 324 | 344 | 367 | 401 | 0.0788 | 1231 | 0.960 | 135.72 | 35.01 | 1 | 0.0352 | 320 | 0.0013 | 28.86 | 6.929 | 0.2122 | 101409.0 | 34600000 | 12300000000 | 4590000000000 | 0.4537 | 0.2035 | 0.0010 | 0.0000 | 0.0019 | 0.0001 | 0.0068 | 0.0009 | 0.0222 | 0.0025 | 0.0705 | 0.0167 | 0.1362 | 0.0410 | 0.1452 | 0.0416 | 0.1613 | 0.0640 | 0.4548 | 0.8331 | 0.0007 | 0.0000 | 0.0005 | 0.0000 | 0.0027 | 0.0006 | 0.0099 | 0.0020 | 0.0293 | 0.0115 | 0.0662 | 0.0283 | 0.0633 | 0.0223 | 0.0823 | 0.0364 | 0.7452 | 0.8989 | 0.0056 | 0.0027 | 0.0124 | 0.0318 | 0.0204 | 0.0637 | 0.0667 | 0.1141 | 0.1248 | 0.2042 | 0.1513 | 0.1485 | 0.1328 | 0.0716 | 0.1575 | 0.1300 | 0.3286 | 0.2334 | 0.0007 | 0.0030 | 0.0096 | 0.0287 | 0.0674 | 0.1168 | 0.1070 | 0.1261 | 0.5408 | 12 | 14 | 17 | 23 | 41 | 74 | 118 | 173 | 260 | 0.0390 | 25.52 | 5.297 | 0.4490 | 24490.2 | 9030000 | 4150000000 | 2200000000000 | 0.5460 | 0.1292 | 0.0690 | 0.0018 | 0.1999 | 0.0187 | 0.2994 | 0.1257 | 0.1613 | 0.1617 | 0.1323 | 0.2185 | 0.0814 | 0.1892 | 0.0378 | 0.1186 | 0.0145 | 0.0981 | 0.0044 | 0.0678 | 0.0002 | 0.0003 | 0.0012 | 0.0006 | 0.0031 | 0.0027 | 0.0151 | 0.0124 | 0.0691 | 0.0593 | 0.1090 | 0.0934 | 0.0785 | 0.0690 | 0.1141 | 0.1000 | 0.6096 | 0.6622 | 0.0011 | 0.0015 | 0.0023 | 0.0025 | 0.0079 | 0.0093 | 0.0234 | 0.0284 | 0.0888 | 0.0944 | 0.1239 | 0.1444 | 0.0960 | 0.0946 | 0.1298 | 0.1284 | 0.5268 | 0.4966 | 0.0002 | 0.0022 | 0.0039 | 0.0202 | 0.0788 | 0.1208 | 0.0884 | 0.1238 | 0.5618 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 872 | 575 | | 6042 | 12072 | 101.1 | 29.15 | 201.53 | 223.69 | 69 | 77 | 84 | 91 | 97 | 103 | 110 | 120 | 139 | 0.0696 | 840 | 0.813 | 79.88 | 25.94 | 1 | 0.0386 | 233 | 0.0015 | 30.07 | 6.806 | 0.2198 | 11069.0 | 1320000 | 170000000 | 23900000000 | 0.4862 | 0.1865 | 0.0018 | 0.0002 | 0.0053 | 0.0006 | 0.0143 | 0.0023 | 0.0289 | 0.0069 | 0.0949 | 0.0296 | 0.1530 | 0.0590 | 0.1434 | 0.0611 | 0.1755 | 0.0846 | 0.3829 | 0.7558 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0024 | 0.0005 | 0.0109 | 0.0028 | 0.0454 | 0.0160 | 0.0803 | 0.0329 | 0.0748 | 0.0325 | 0.1071 | 0.0463 | 0.6782 | 0.8690 | 0.0043 | 0.0000 | 0.0017 | 0.0123 | 0.0112 | 0.0334 | 0.0543 | 0.0598 | 0.1422 | 0.1652 | 0.1716 | 0.1845 | 0.1112 | 0.1037 | 0.1362 | 0.1564 | 0.3672 | 0.2847 | 0.0008 | 0.0053 | 0.0162 | 0.0442 | 0.0797 | 0.1330 | 0.1035 | 0.1300 | 0.4873 | 18 | 30 | 47 | 67 | 108 | 171 | 253 | 356 | 517 | 0.0128 | 34.28 | 6.003 | 0.4255 | 90647.1 | 57700000 | 45300000000 | 41800000000000 | 0.5238 | 0.1388 | 0.0299 | 0.0012 | 0.1106 | 0.0112 | 0.2542 | 0.0630 | 0.1719 | 0.1064 | 0.1356 | 0.1694 | 0.1203 | 0.2041 | 0.0759 | 0.1291 | 0.0581 | 0.1283 | 0.0436 | 0.1873 | 0.0002 | 0.0003 | 0.0012 | 0.0009 | 0.0024 | 0.0014 | 0.0120 | 0.0077 | 0.0503 | 0.0456 | 0.0918 | 0.0772 | 0.0637 | 0.0548 | 0.0892 | 0.0894 | 0.6892 | 0.7227 | 0.0008 | 0.0000 | 0.0005 | 0.0016 | 0.0040 | 0.0062 | 0.0171 | 0.0230 | 0.0656 | 0.0792 | 0.1207 | 0.1321 | 0.0874 | 0.0879 | 0.1189 | 0.1252 | 0.5850 | 0.5447 | 0.0005 | 0.0016 | 0.0021 | 0.0115 | 0.0607 | 0.1004 | 0.0736 | 0.1068 | 0.6429 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 655 | 519 | | 12431 | 24620 | 390.0 | 70.08 | 73.02 | 145.52 | 287 | 322 | 350 | 376 | 398 | 418 | 437 | 454 | 476 | 0.0531 | 1307 | 0.717 | 116.71 | 35.11 | 3 | 0.0323 | 401 | 0.0014 | 13.24 | 6.814 | 0.3028 | 157023.0 | 65000000 | 27500000000 | 11900000000000 | 0.4378 | 0.1981 | 0.0007 | 0.0000 | 0.0029 | 0.0000 | 0.0055 | 0.0000 | 0.0115 | 0.0009 | 0.0276 | 0.0098 | 0.0447 | 0.0175 | 0.0492 | 0.0111 | 0.0732 | 0.0171 | 0.7847 | 0.9436 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0000 | 0.0037 | 0.0009 | 0.0122 | 0.0098 | 0.0195 | 0.0175 | 0.0178 | 0.0105 | 0.0271 | 0.0152 | 0.9168 | 0.9461 | 0.0102 | 1.0000 | 0.0215 | 0.0000 | 0.0269 | 0.0000 | 0.0449 | 0.0000 | 0.0682 | 0.0000 | 0.0922 | 0.0000 | 0.0999 | 0.0000 | 0.1191 | 0.0000 | 0.5171 | 0.0000 | 0.0007 | 0.0036 | 0.0042 | 0.0104 | 0.0227 | 0.0348 | 0.0407 | 0.0547 | 0.8282 | 8 | 10 | 11 | 13 | 15 | 20 | 33 | 82 | 218 | 0.1379 | 2.58 | 2.741 | 0.6004 | 26508.4 | 16200000 | 12600000000 | 11400000000000 | 0.6289 | 0.0769 | 0.0413 | 0.0027 | 0.1013 | 0.0182 | 0.1888 | 0.0633 | 0.1750 | 0.0919 | 0.1721 | 0.1461 | 0.1327 | 0.1875 | 0.1013 | 0.1379 | 0.0560 | 0.1347 | 0.0315 | 0.2176 | 0.0002 | 0.0005 | 0.0007 | 0.0006 | 0.0016 | 0.0015 | 0.0123 | 0.0101 | 0.0446 | 0.0428 | 0.0768 | 0.0683 | 0.0519 | 0.0466 | 0.0718 | 0.0703 | 0.7402 | 0.7592 | 0.0004 | 0.0009 | 0.0008 | 0.0018 | 0.0023 | 0.0018 | 0.0159 | 0.0140 | 0.0529 | 0.0605 | 0.0898 | 0.0918 | 0.0567 | 0.0628 | 0.0814 | 0.0868 | 0.6997 | 0.6794 | 0.0004 | 0.0000 | 0.0015 | 0.0114 | 0.0529 | 0.0806 | 0.0550 | 0.0825 | 0.7157 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 835 | 674 | | 1286 | 9006 | 107.9 | 35.92 | 236.20 | 179.35 | 71 | 83 | 90 | 96 | 102 | 108 | 115 | 126 | 148 | 0.0815 | 734 | 0.834 | 60.64 | 18.97 | 2 | 0.1260 | 162 | 0.0037 | 21.25 | 5.914 | 0.2852 | 12925.5 | 1750000 | 272000000 | 48100000000 | 0.4873 | 0.1534 | 0.0027 | 0.0000 | 0.0054 | 0.0036 | 0.0308 | 0.0055 | 0.0496 | 0.0173 | 0.1300 | 0.0656 | 0.1662 | 0.0911 | 0.1421 | 0.0647 | 0.1568 | 0.1047 | 0.3164 | 0.6475 | 0.0000 | 0.0000 | 0.0031 | 0.0016 | 0.0134 | 0.0033 | 0.0237 | 0.0124 | 0.0792 | 0.0437 | 0.1132 | 0.0766 | 0.0792 | 0.0445 | 0.1091 | 0.0807 | 0.5792 | 0.7372 | 0.0088 | 0.0086 | 0.0088 | 0.0172 | 0.0265 | 0.0172 | 0.0929 | 0.0862 | 0.1106 | 0.1034 | 0.1593 | 0.1724 | 0.0885 | 0.0690 | 0.1283 | 0.1379 | 0.3761 | 0.3879 | 0.0038 | 0.0095 | 0.0302 | 0.0624 | 0.1078 | 0.1229 | 0.1096 | 0.1153 | 0.4386 | 21 | 54 | 101 | 156 | 212 | 269 | 324 | 398 | 492 | 0.0054 | 44.25 | 6.916 | 0.2857 | 87951.8 | 39600000 | 20100000000 | 11200000000000 | 0.5258 | 0.1424 | 0.0084 | 0.0013 | 0.0560 | 0.0023 | 0.1925 | 0.0179 | 0.2183 | 0.0737 | 0.2022 | 0.1661 | 0.1481 | 0.2268 | 0.0959 | 0.1657 | 0.0541 | 0.1561 | 0.0245 | 0.1900 | 0.0002 | 0.0002 | 0.0010 | 0.0009 | 0.0047 | 0.0025 | 0.0137 | 0.0101 | 0.0490 | 0.0402 | 0.0890 | 0.0809 | 0.0733 | 0.0592 | 0.1002 | 0.0870 | 0.6689 | 0.7190 | 0.0012 | 0.0019 | 0.0030 | 0.0054 | 0.0075 | 0.0103 | 0.0251 | 0.0387 | 0.0681 | 0.0831 | 0.1282 | 0.1543 | 0.1091 | 0.1091 | 0.1372 | 0.1313 | 0.5206 | 0.4659 | 0.0007 | 0.0036 | 0.0053 | 0.0177 | 0.0540 | 0.1087 | 0.0856 | 0.1201 | 0.6042 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 448 | 583 | | 4870 | 11803 | 145.2 | 35.55 | 166.28 | 141.22 | 106 | 119 | 129 | 136 | 143 | 150 | 157 | 166 | 182 | 0.0848 | 1001 | 1.080 | 90.80 | 26.02 | 1 | 0.0448 | 218 | 0.0023 | 21.25 | 6.376 | 0.2593 | 22352.9 | 3700000 | 674000000 | 140000000000 | 0.5233 | 0.1537 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0063 | 0.0020 | 0.0186 | 0.0059 | 0.0714 | 0.0204 | 0.1461 | 0.0576 | 0.1467 | 0.0492 | 0.1833 | 0.0730 | 0.4263 | 0.7916 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0017 | 0.0013 | 0.0087 | 0.0044 | 0.0397 | 0.0176 | 0.0788 | 0.0439 | 0.0694 | 0.0279 | 0.1031 | 0.0468 | 0.6983 | 0.8580 | 0.0071 | 0.0138 | 0.0228 | 0.0276 | 0.0342 | 0.0369 | 0.1198 | 0.1244 | 0.1641 | 0.1982 | 0.1897 | 0.1935 | 0.1227 | 0.0599 | 0.1098 | 0.1152 | 0.2297 | 0.2304 | 0.0030 | 0.0056 | 0.0155 | 0.0494 | 0.0975 | 0.1375 | 0.1224 | 0.1538 | 0.4154 | 18 | 39 | 68 | 100 | 133 | 170 | 213 | 270 | 362 | 0.0037 | 57.89 | 6.920 | 0.2988 | 47591.3 | 18100000 | 8370000000 | 4450000000000 | 0.4521 | 0.1774 | 0.0099 | 0.0010 | 0.0727 | 0.0018 | 0.1824 | 0.0223 | 0.1760 | 0.0674 | 0.2042 | 0.1490 | 0.1715 | 0.2039 | 0.0989 | 0.1663 | 0.0578 | 0.1655 | 0.0267 | 0.2229 | 0.0002 | 0.0000 | 0.0010 | 0.0008 | 0.0039 | 0.0034 | 0.0108 | 0.0072 | 0.0510 | 0.0340 | 0.0877 | 0.0683 | 0.0730 | 0.0617 | 0.1087 | 0.0831 | 0.6637 | 0.7415 | 0.0013 | 0.0019 | 0.0013 | 0.0061 | 0.0077 | 0.0145 | 0.0286 | 0.0352 | 0.0848 | 0.1044 | 0.1358 | 0.1322 | 0.1054 | 0.1131 | 0.1247 | 0.1251 | 0.5106 | 0.4674 | 0.0006 | 0.0029 | 0.0045 | 0.0181 | 0.0642 | 0.1082 | 0.0990 | 0.1199 | 0.5826 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 158 | 814 | | 6792 | 9233 | 438.4 | 87.62 | 129.25 | 126.89 | 328 | 360 | 387 | 410 | 432 | 453 | 478 | 510 | 563 | 0.1039 | 959 | 1.120 | 105.12 | 29.02 | 1 | 0.0346 | 235 | 0.0009 | 45.63 | 7.284 | 0.1766 | 199847.0 | 94600000 | 46500000000 | 23600000000000 | 0.4114 | 0.2340 | 0.0002 | 0.0000 | 0.0009 | 0.0002 | 0.0029 | 0.0003 | 0.0152 | 0.0014 | 0.0530 | 0.0166 | 0.1082 | 0.0302 | 0.1148 | 0.0269 | 0.1594 | 0.0440 | 0.5454 | 0.8804 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0012 | 0.0000 | 0.0064 | 0.0000 | 0.0246 | 0.0109 | 0.0515 | 0.0199 | 0.0494 | 0.0108 | 0.0729 | 0.0223 | 0.7933 | 0.9361 | 0.0091 | 0.0087 | 0.0172 | 0.0435 | 0.0199 | 0.0913 | 0.0661 | 0.1174 | 0.1024 | 0.2261 | 0.1386 | 0.1174 | 0.1232 | 0.1739 | 0.1132 | 0.0870 | 0.4103 | 0.1348 | 0.0006 | 0.0025 | 0.0094 | 0.0253 | 0.0738 | 0.1200 | 0.1088 | 0.1385 | 0.5211 | 15 | 21 | 36 | 60 | 91 | 123 | 163 | 221 | 310 | 0.0144 | 22.41 | 5.893 | 0.4120 | 32805.8 | 11500000 | 4920000000 | 2420000000000 | 0.5918 | 0.1102 | 0.0326 | 0.0008 | 0.0932 | 0.0126 | 0.1546 | 0.0502 | 0.1430 | 0.0942 | 0.1492 | 0.1468 | 0.1430 | 0.1554 | 0.1072 | 0.1181 | 0.1049 | 0.1370 | 0.0723 | 0.2849 | 0.0002 | 0.0000 | 0.0012 | 0.0004 | 0.0062 | 0.0042 | 0.0208 | 0.0156 | 0.0649 | 0.0540 | 0.0900 | 0.0828 | 0.0815 | 0.0608 | 0.1083 | 0.0905 | 0.6269 | 0.6917 | 0.0017 | 0.0008 | 0.0031 | 0.0078 | 0.0133 | 0.0090 | 0.0269 | 0.0377 | 0.0941 | 0.1099 | 0.1339 | 0.1333 | 0.0896 | 0.1005 | 0.1210 | 0.1255 | 0.5164 | 0.4754 | 0.0009 | 0.0028 | 0.0079 | 0.0247 | 0.0791 | 0.1123 | 0.0879 | 0.1140 | 0.5705 | ||
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 845 | 391 | | 8714 | 28501 | 282.2 | 64.28 | 121.16 | 121.03 | 206 | 227 | 243 | 259 | 276 | 293 | 313 | 334 | 368 | 0.0454 | 1293 | 1.148 | 102.08 | 30.46 | 1 | 0.0270 | 235 | 0.0023 | 14.79 | 6.394 | 0.2854 | 83742.3 | 26100000 | 8530000000 | 2910000000000 | 0.4516 | 0.1999 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0048 | 0.0004 | 0.0140 | 0.0014 | 0.0658 | 0.0182 | 0.1361 | 0.0403 | 0.1469 | 0.0472 | 0.1796 | 0.0612 | 0.4515 | 0.8313 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0002 | 0.0057 | 0.0007 | 0.0319 | 0.0118 | 0.0595 | 0.0218 | 0.0612 | 0.0237 | 0.0824 | 0.0326 | 0.7570 | 0.9091 | 0.0044 | 0.0000 | 0.0062 | 0.0143 | 0.0187 | 0.0531 | 0.0704 | 0.0755 | 0.1172 | 0.1633 | 0.1509 | 0.2286 | 0.1010 | 0.0857 | 0.1415 | 0.1429 | 0.3897 | 0.2367 | 0.0005 | 0.0007 | 0.0074 | 0.0253 | 0.0763 | 0.1144 | 0.0817 | 0.1207 | 0.5730 | 16 | 28 | 45 | 64 | 86 | 111 | 142 | 189 | 270 | 0.0173 | 10.15 | 5.255 | 0.4896 | 29326.3 | 11100000 | 5770000000 | 3740000000000 | 0.5092 | 0.1670 | 0.0151 | 0.0015 | 0.0740 | 0.0061 | 0.1650 | 0.0287 | 0.1715 | 0.0720 | 0.1760 | 0.1555 | 0.1560 | 0.1872 | 0.1115 | 0.1505 | 0.0848 | 0.1481 | 0.0462 | 0.2505 | 0.0002 | 0.0005 | 0.0014 | 0.0011 | 0.0052 | 0.0033 | 0.0204 | 0.0126 | 0.0607 | 0.0488 | 0.0975 | 0.0843 | 0.0811 | 0.0687 | 0.1062 | 0.0968 | 0.6273 | 0.6839 | 0.0018 | 0.0015 | 0.0029 | 0.0027 | 0.0062 | 0.0087 | 0.0255 | 0.0332 | 0.0815 | 0.0912 | 0.1277 | 0.1335 | 0.0916 | 0.0982 | 0.1235 | 0.1301 | 0.5393 | 0.5010 | 0.0013 | 0.0021 | 0.0052 | 0.0239 | 0.0719 | 0.1113 | 0.0898 | 0.1163 | 0.5781 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1168 | 424 | | 6546 | 17083 | 401.6 | 88.26 | 135.51 | 179.85 | 299 | 325 | 346 | 367 | 388 | 411 | 439 | 479 | 531 | 0.0520 | 889 | 1.155 | 97.74 | 36.50 | 1 | 0.0390 | 255 | 0.0006 | 73.03 | 7.599 | 0.1457 | 169066.0 | 74500000 | 34300000000 | 16500000000000 | 0.4391 | 0.2054 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0024 | 0.0003 | 0.0156 | 0.0020 | 0.0721 | 0.0202 | 0.1564 | 0.0399 | 0.1454 | 0.0398 | 0.1652 | 0.0640 | 0.4415 | 0.8338 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0067 | 0.0003 | 0.0328 | 0.0108 | 0.0762 | 0.0234 | 0.0686 | 0.0168 | 0.0916 | 0.0321 | 0.7229 | 0.9166 | 0.0000 | 0.0086 | 0.0056 | 0.0115 | 0.0104 | 0.0576 | 0.0569 | 0.1124 | 0.1018 | 0.1960 | 0.1604 | 0.2219 | 0.1099 | 0.1441 | 0.1299 | 0.1210 | 0.4250 | 0.1268 | 0.0014 | 0.0056 | 0.0112 | 0.0352 | 0.0715 | 0.1141 | 0.0855 | 0.1018 | 0.5738 | 6 | 9 | 12 | 24 | 53 | 96 | 159 | 245 | 398 | 0.0690 | 25.10 | 5.074 | 0.4896 | 50707.9 | 26800000 | 17300000000 | 12900000000000 | 0.5220 | 0.1303 | 0.0750 | 0.0031 | 0.1918 | 0.0288 | 0.2725 | 0.1436 | 0.1472 | 0.1470 | 0.1168 | 0.1845 | 0.0842 | 0.1772 | 0.0566 | 0.1189 | 0.0340 | 0.0954 | 0.0219 | 0.1016 | 0.0002 | 0.0003 | 0.0006 | 0.0001 | 0.0031 | 0.0029 | 0.0159 | 0.0113 | 0.0618 | 0.0534 | 0.1096 | 0.0985 | 0.0694 | 0.0658 | 0.1005 | 0.0962 | 0.6390 | 0.6716 | 0.0004 | 0.0009 | 0.0024 | 0.0025 | 0.0050 | 0.0096 | 0.0203 | 0.0215 | 0.0764 | 0.0900 | 0.1299 | 0.1292 | 0.0772 | 0.0830 | 0.1085 | 0.1212 | 0.5799 | 0.5421 | 0.0004 | 0.0014 | 0.0042 | 0.0152 | 0.0716 | 0.1197 | 0.0695 | 0.1083 | 0.6097 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 211 | 348 | | 4562 | 14662 | 292.1 | 59.07 | 135.81 | 209.30 | 220 | 241 | 258 | 274 | 289 | 304 | 320 | 340 | 367 | 0.0645 | 945 | 0.932 | 136.85 | 50.12 | 1 | 0.0855 | 390 | 0.0007 | 74.36 | 7.435 | 0.1412 | 88808.4 | 28100000 | 9250000000 | 3170000000000 | 0.4402 | 0.2161 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0029 | 0.0000 | 0.0167 | 0.0014 | 0.0694 | 0.0171 | 0.1478 | 0.0364 | 0.1491 | 0.0316 | 0.1825 | 0.0583 | 0.4299 | 0.8552 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0018 | 0.0000 | 0.0071 | 0.0004 | 0.0325 | 0.0141 | 0.0723 | 0.0270 | 0.0621 | 0.0175 | 0.0948 | 0.0314 | 0.7283 | 0.9096 | 0.0085 | 0.0305 | 0.0142 | 0.0534 | 0.0355 | 0.0763 | 0.1050 | 0.1374 | 0.1475 | 0.1527 | 0.2014 | 0.1450 | 0.1078 | 0.1145 | 0.1362 | 0.1069 | 0.2440 | 0.1832 | 0.0009 | 0.0045 | 0.0095 | 0.0345 | 0.0971 | 0.1324 | 0.1261 | 0.1515 | 0.4435 | 11 | 12 | 14 | 17 | 22 | 47 | 116 | 250 | 458 | 0.0764 | 33.39 | 4.749 | 0.5335 | 62246.8 | 39200000 | 28700000000 | 23200000000000 | 0.5235 | 0.1167 | 0.0898 | 0.0014 | 0.2511 | 0.0304 | 0.2735 | 0.1824 | 0.1276 | 0.2041 | 0.1024 | 0.2020 | 0.0589 | 0.1399 | 0.0449 | 0.0878 | 0.0337 | 0.0662 | 0.0182 | 0.0858 | 0.0002 | 0.0002 | 0.0002 | 0.0002 | 0.0026 | 0.0024 | 0.0088 | 0.0086 | 0.0505 | 0.0448 | 0.0827 | 0.0772 | 0.0569 | 0.0558 | 0.0882 | 0.0792 | 0.7098 | 0.7318 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0021 | 0.0017 | 0.0094 | 0.0111 | 0.0555 | 0.0599 | 0.0916 | 0.1008 | 0.0699 | 0.0806 | 0.1010 | 0.1079 | 0.6706 | 0.6378 | 0.0002 | 0.0015 | 0.0015 | 0.0077 | 0.0503 | 0.0907 | 0.0609 | 0.0912 | 0.6961 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 346 | 701 | | 14198 | 40387 | 106.4 | 32.10 | 146.17 | 188.92 | 72 | 82 | 90 | 96 | 103 | 110 | 118 | 129 | 144 | 0.0393 | 1589 | 0.755 | 201.22 | 48.27 | 2 | 0.0373 | 529 | 0.0026 | 18.07 | 6.363 | 0.2881 | 12345.6 | 1580000 | 229000000 | 39000000000 | 0.4708 | 0.1852 | 0.0007 | 0.0001 | 0.0041 | 0.0010 | 0.0119 | 0.0011 | 0.0333 | 0.0042 | 0.0850 | 0.0218 | 0.1598 | 0.0539 | 0.1708 | 0.0533 | 0.1970 | 0.0847 | 0.3372 | 0.7798 | 0.0002 | 0.0000 | 0.0011 | 0.0001 | 0.0015 | 0.0003 | 0.0096 | 0.0013 | 0.0331 | 0.0130 | 0.0687 | 0.0281 | 0.0706 | 0.0210 | 0.1052 | 0.0352 | 0.7101 | 0.9010 | 0.0061 | 0.0103 | 0.0105 | 0.0240 | 0.0243 | 0.0326 | 0.0723 | 0.1021 | 0.1348 | 0.1501 | 0.1713 | 0.1827 | 0.1203 | 0.1226 | 0.1413 | 0.1389 | 0.3190 | 0.2367 | 0.0017 | 0.0051 | 0.0119 | 0.0353 | 0.0818 | 0.1125 | 0.1127 | 0.1276 | 0.5114 | 12 | 14 | 17 | 21 | 38 | 97 | 181 | 289 | 433 | 0.0636 | 63.25 | 5.587 | 0.4594 | 57055.8 | 29900000 | 18300000000 | 12600000000000 | 0.5337 | 0.1336 | 0.0936 | 0.0033 | 0.2406 | 0.0356 | 0.2573 | 0.2023 | 0.1157 | 0.1813 | 0.1154 | 0.1677 | 0.0874 | 0.1514 | 0.0464 | 0.0816 | 0.0283 | 0.0770 | 0.0152 | 0.0996 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0022 | 0.0010 | 0.0084 | 0.0066 | 0.0488 | 0.0425 | 0.1001 | 0.0859 | 0.0667 | 0.0576 | 0.0957 | 0.0872 | 0.6770 | 0.7188 | 0.0006 | 0.0001 | 0.0009 | 0.0017 | 0.0039 | 0.0037 | 0.0107 | 0.0152 | 0.0648 | 0.0721 | 0.1272 | 0.1439 | 0.0905 | 0.0989 | 0.1204 | 0.1231 | 0.5809 | 0.5414 | 0.0005 | 0.0010 | 0.0023 | 0.0103 | 0.0565 | 0.1095 | 0.0807 | 0.1143 | 0.6250 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 154 | 245 | | 7441 | 18098 | 595.1 | 99.87 | 158.05 | 276.24 | 459 | 515 | 549 | 576 | 598 | 618 | 640 | 669 | 725 | 0.0530 | 960 | 0.791 | 112.90 | 27.89 | 2 | 0.0372 | 277 | 0.0011 | 26.39 | 7.165 | 0.2288 | 364116.0 | 229000000 | 147000000000 | 96900000000000 | 0.4475 | 0.1984 | 0.0002 | 0.0000 | 0.0007 | 0.0001 | 0.0016 | 0.0000 | 0.0053 | 0.0005 | 0.0258 | 0.0124 | 0.0455 | 0.0206 | 0.0458 | 0.0151 | 0.0692 | 0.0230 | 0.8059 | 0.9282 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0003 | 0.0163 | 0.0116 | 0.0267 | 0.0174 | 0.0252 | 0.0115 | 0.0358 | 0.0181 | 0.8938 | 0.9412 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0292 | 0.0000 | 0.0560 | 0.0000 | 0.0840 | 0.0000 | 0.0793 | 0.0000 | 0.1039 | 0.0000 | 0.6196 | 0.0000 | 0.0018 | 0.0036 | 0.0094 | 0.0214 | 0.0420 | 0.0641 | 0.0646 | 0.0876 | 0.7055 | 11 | 14 | 17 | 20 | 25 | 35 | 85 | 239 | 575 | 0.1535 | 16.74 | 4.037 | 0.6476 | 101285.0 | 90600000 | 95000000000 | 112000000000000 | 0.3437 | 0.2785 | 0.0470 | 0.0020 | 0.1678 | 0.0214 | 0.1893 | 0.0935 | 0.1530 | 0.1136 | 0.1732 | 0.1877 | 0.0980 | 0.1717 | 0.0779 | 0.1236 | 0.0671 | 0.1142 | 0.0268 | 0.1723 | 0.0002 | 0.0000 | 0.0008 | 0.0002 | 0.0008 | 0.0013 | 0.0102 | 0.0086 | 0.0376 | 0.0335 | 0.0599 | 0.0539 | 0.0436 | 0.0392 | 0.0626 | 0.0588 | 0.7843 | 0.8046 | 0.0000 | 0.0003 | 0.0012 | 0.0000 | 0.0042 | 0.0040 | 0.0138 | 0.0138 | 0.0413 | 0.0458 | 0.0655 | 0.0684 | 0.0487 | 0.0468 | 0.0667 | 0.0620 | 0.7586 | 0.7589 | 0.0002 | 0.0007 | 0.0023 | 0.0114 | 0.0416 | 0.0654 | 0.0444 | 0.0633 | 0.7707 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 855 | 295 | | 10991 | 23655 | 262.5 | 76.92 | 158.35 | 201.26 | 177 | 198 | 216 | 232 | 250 | 269 | 292 | 321 | 366 | 0.0567 | 1341 | 1.156 | 118.61 | 44.10 | 2 | 0.0278 | 305 | 0.0005 | 81.23 | 7.822 | 0.1418 | 74835.2 | 23200000 | 7750000000 | 2800000000000 | 0.4804 | 0.1627 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0071 | 0.0009 | 0.0294 | 0.0045 | 0.0907 | 0.0256 | 0.1763 | 0.0635 | 0.1516 | 0.0562 | 0.1834 | 0.0790 | 0.3603 | 0.7703 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0004 | 0.0117 | 0.0023 | 0.0349 | 0.0146 | 0.0759 | 0.0366 | 0.0625 | 0.0262 | 0.0909 | 0.0372 | 0.7224 | 0.8828 | 0.0004 | 0.0038 | 0.0059 | 0.0084 | 0.0143 | 0.0188 | 0.0412 | 0.0619 | 0.1017 | 0.1210 | 0.1509 | 0.1642 | 0.1076 | 0.1098 | 0.1366 | 0.1407 | 0.4414 | 0.3715 | 0.0008 | 0.0036 | 0.0096 | 0.0273 | 0.0644 | 0.1087 | 0.0818 | 0.1101 | 0.5937 | 10 | 12 | 15 | 20 | 43 | 109 | 209 | 323 | 476 | 0.0700 | 31.05 | 5.286 | 0.4973 | 65578.9 | 35100000 | 21700000000 | 15000000000000 | 0.5467 | 0.1326 | 0.0587 | 0.0020 | 0.2015 | 0.0205 | 0.3009 | 0.1523 | 0.1628 | 0.1523 | 0.1274 | 0.1764 | 0.0861 | 0.1946 | 0.0327 | 0.1099 | 0.0254 | 0.0900 | 0.0047 | 0.1020 | 0.0002 | 0.0002 | 0.0004 | 0.0001 | 0.0015 | 0.0005 | 0.0054 | 0.0054 | 0.0421 | 0.0359 | 0.0826 | 0.0761 | 0.0556 | 0.0480 | 0.0768 | 0.0648 | 0.7354 | 0.7690 | 0.0001 | 0.0000 | 0.0009 | 0.0009 | 0.0029 | 0.0031 | 0.0107 | 0.0130 | 0.0544 | 0.0570 | 0.1019 | 0.1180 | 0.0672 | 0.0698 | 0.0986 | 0.1004 | 0.6631 | 0.6377 | 0.0001 | 0.0002 | 0.0014 | 0.0079 | 0.0478 | 0.0936 | 0.0584 | 0.0901 | 0.7003 |