High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 819 | 837 | | 4077 | 7402 | 164.0 | 45.49 | 281.51 | 208.60 | 106 | 126 | 139 | 150 | 161 | 172 | 185 | 201 | 225 | 0.0809 | 599 | 0.666 | 68.59 | 22.56 | 2 | 0.0518 | 211 | 0.0013 | 30.19 | 6.879 | 0.2104 | 28976.0 | 5470000 | 1100000000 | 232000000000 | 0.4785 | 0.1795 | 0.0028 | 0.0000 | 0.0032 | 0.0006 | 0.0065 | 0.0020 | 0.0341 | 0.0061 | 0.1138 | 0.0314 | 0.1876 | 0.0802 | 0.1618 | 0.0709 | 0.1834 | 0.0994 | 0.3069 | 0.7095 | 0.0006 | 0.0000 | 0.0010 | 0.0003 | 0.0019 | 0.0005 | 0.0081 | 0.0026 | 0.0430 | 0.0195 | 0.0783 | 0.0445 | 0.0608 | 0.0306 | 0.0935 | 0.0458 | 0.7126 | 0.8562 | 0.0043 | 0.0113 | 0.0185 | 0.0226 | 0.0120 | 0.0452 | 0.0663 | 0.1271 | 0.1261 | 0.1582 | 0.1815 | 0.2345 | 0.1239 | 0.1356 | 0.1424 | 0.0989 | 0.3250 | 0.1667 | 0.0015 | 0.0021 | 0.0072 | 0.0355 | 0.0762 | 0.1340 | 0.1061 | 0.1175 | 0.5198 | 41 | 86 | 136 | 190 | 247 | 308 | 370 | 448 | 564 | 0.0018 | 128.90 | 7.431 | 0.1991 | 122752.0 | 67400000 | 43400000000 | 31600000000000 | 0.5494 | 0.1250 | 0.0218 | 0.0004 | 0.1102 | 0.0047 | 0.2408 | 0.0505 | 0.1748 | 0.0920 | 0.1769 | 0.1749 | 0.1363 | 0.2080 | 0.0798 | 0.1531 | 0.0428 | 0.1385 | 0.0167 | 0.1778 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0011 | 0.0151 | 0.0089 | 0.0627 | 0.0498 | 0.1204 | 0.0924 | 0.0929 | 0.0759 | 0.1327 | 0.1043 | 0.5715 | 0.6676 | 0.0000 | 0.0020 | 0.0042 | 0.0036 | 0.0096 | 0.0137 | 0.0301 | 0.0493 | 0.1131 | 0.1301 | 0.1521 | 0.1876 | 0.1212 | 0.1256 | 0.1613 | 0.1520 | 0.4083 | 0.3360 | 0.0015 | 0.0024 | 0.0049 | 0.0182 | 0.0809 | 0.1469 | 0.1031 | 0.1338 | 0.5082 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1020 | 437 | | 7708 | 18612 | 422.4 | 67.92 | 139.42 | 205.57 | 338 | 363 | 382 | 400 | 419 | 436 | 456 | 480 | 516 | 0.0529 | 985 | 1.200 | 83.10 | 36.12 | 1 | 0.0294 | 227 | 0.0008 | 46.82 | 7.310 | 0.1734 | 183017.0 | 81300000 | 37000000000 | 17200000000000 | 0.4380 | 0.2129 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0001 | 0.0063 | 0.0003 | 0.0381 | 0.0119 | 0.0754 | 0.0187 | 0.0832 | 0.0153 | 0.1243 | 0.0245 | 0.6713 | 0.9293 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0001 | 0.0203 | 0.0112 | 0.0379 | 0.0157 | 0.0403 | 0.0104 | 0.0599 | 0.0156 | 0.8392 | 0.9471 | 0.0075 | 0.0000 | 0.0118 | 0.0000 | 0.0236 | 0.0000 | 0.0675 | 0.0000 | 0.1263 | 0.0000 | 0.1649 | 0.0000 | 0.1113 | 0.0000 | 0.1349 | 0.0000 | 0.3522 | 0.0000 | 0.0013 | 0.0019 | 0.0078 | 0.0317 | 0.0666 | 0.1048 | 0.1005 | 0.1115 | 0.5740 | 10 | 12 | 14 | 18 | 26 | 54 | 132 | 275 | 460 | 0.1177 | 30.91 | 4.625 | 0.5832 | 61695.7 | 37000000 | 26000000000 | 20500000000000 | 0.5639 | 0.1251 | 0.1199 | 0.0027 | 0.3225 | 0.0469 | 0.2770 | 0.2340 | 0.1271 | 0.2073 | 0.0875 | 0.1942 | 0.0372 | 0.1189 | 0.0168 | 0.0802 | 0.0108 | 0.0627 | 0.0012 | 0.0529 | 0.0002 | 0.0000 | 0.0010 | 0.0012 | 0.0020 | 0.0017 | 0.0102 | 0.0098 | 0.0543 | 0.0504 | 0.0817 | 0.0716 | 0.0611 | 0.0529 | 0.0974 | 0.0820 | 0.6921 | 0.7303 | 0.0002 | 0.0004 | 0.0018 | 0.0028 | 0.0035 | 0.0030 | 0.0106 | 0.0119 | 0.0670 | 0.0774 | 0.1038 | 0.1070 | 0.0723 | 0.0864 | 0.1182 | 0.1269 | 0.6226 | 0.5842 | 0.0000 | 0.0009 | 0.0026 | 0.0119 | 0.0552 | 0.1008 | 0.0649 | 0.1025 | 0.6613 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 791 | 738 | | 2836 | 2758 | 119.5 | 28.32 | 225.10 | 172.38 | 89 | 99 | 105 | 111 | 115 | 121 | 128 | 137 | 155 | 0.1653 | 456 | 0.603 | 236.69 | 51.26 | 1 | 0.2341 | 664 | 0.0036 | 15.13 | 5.972 | 0.2993 | 15085.0 | 2020000 | 291000000 | 45400000000 | 0.4422 | 0.2144 | 0.0000 | 0.0000 | 0.0005 | 0.0004 | 0.0021 | 0.0000 | 0.0185 | 0.0042 | 0.0723 | 0.0261 | 0.1083 | 0.0465 | 0.1591 | 0.0519 | 0.1657 | 0.0711 | 0.4736 | 0.7998 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0067 | 0.0011 | 0.0387 | 0.0176 | 0.0627 | 0.0269 | 0.0753 | 0.0298 | 0.0867 | 0.0384 | 0.7285 | 0.8863 | 0.0070 | 0.0054 | 0.0234 | 0.0163 | 0.0422 | 0.0217 | 0.0749 | 0.0761 | 0.1218 | 0.1848 | 0.1124 | 0.1902 | 0.1101 | 0.1196 | 0.1077 | 0.1413 | 0.4005 | 0.2446 | 0.0041 | 0.0033 | 0.0231 | 0.0430 | 0.1017 | 0.1479 | 0.1083 | 0.1380 | 0.4306 | 20 | 53 | 93 | 143 | 203 | 256 | 310 | 368 | 462 | 0.0047 | 47.42 | 6.617 | 0.2813 | 80370.2 | 35100000 | 17400000000 | 9480000000000 | 0.5310 | 0.1251 | 0.0062 | 0.0011 | 0.1040 | 0.0067 | 0.1996 | 0.0540 | 0.2100 | 0.1012 | 0.1580 | 0.1609 | 0.1393 | 0.2014 | 0.1123 | 0.1620 | 0.0499 | 0.1215 | 0.0208 | 0.1912 | 0.0000 | 0.0000 | 0.0007 | 0.0012 | 0.0033 | 0.0024 | 0.0127 | 0.0135 | 0.0560 | 0.0483 | 0.1133 | 0.0889 | 0.0833 | 0.0700 | 0.1227 | 0.0948 | 0.6080 | 0.6810 | 0.0000 | 0.0025 | 0.0010 | 0.0074 | 0.0059 | 0.0086 | 0.0285 | 0.0395 | 0.1050 | 0.1210 | 0.1501 | 0.1444 | 0.0991 | 0.1222 | 0.1511 | 0.1543 | 0.4593 | 0.4000 | 0.0008 | 0.0008 | 0.0032 | 0.0244 | 0.0630 | 0.1198 | 0.1072 | 0.1308 | 0.5500 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 100 | 607 | | 540 | 5580 | 379.2 | 43.12 | 73.69 | 167.23 | 318 | 337 | 353 | 372 | 384 | 393 | 405 | 418 | 436 | 0.0710 | 396 | 0.750 | 109.88 | 35.01 | 2 | 0.6222 | 336 | 0.0034 | 25.50 | 5.823 | 0.2191 | 145633.0 | 56600000 | 22300000000 | 8850000000000 | 0.3869 | 0.2443 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0080 | 0.0019 | 0.0459 | 0.0426 | 0.0719 | 0.0630 | 0.0599 | 0.0315 | 0.0719 | 0.0537 | 0.7405 | 0.8074 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0039 | 0.0019 | 0.0426 | 0.0426 | 0.0638 | 0.0630 | 0.0329 | 0.0315 | 0.0561 | 0.0537 | 0.7988 | 0.8074 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0625 | 0.0000 | 0.1250 | 0.0000 | 0.4375 | 0.0000 | 0.0625 | 0.0000 | 0.2500 | 0.0000 | 0.0625 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0241 | 0.0552 | 0.0897 | 0.0828 | 0.1276 | 0.6138 | 10 | 13 | 15 | 17 | 20 | 25 | 42 | 99 | 162 | 0.2249 | 3.67 | 2.655 | 0.7483 | 33390.0 | 36400000 | 52700000000 | 84800000000000 | 0.5879 | 0.1256 | 0.0385 | 0.0052 | 0.0427 | 0.0174 | 0.1026 | 0.0261 | 0.1880 | 0.0540 | 0.2222 | 0.1237 | 0.1624 | 0.1429 | 0.1496 | 0.1655 | 0.0684 | 0.2003 | 0.0256 | 0.2648 | 0.0007 | 0.0018 | 0.0014 | 0.0043 | 0.0027 | 0.0037 | 0.0075 | 0.0043 | 0.0177 | 0.0178 | 0.0198 | 0.0227 | 0.0355 | 0.0233 | 0.0539 | 0.0491 | 0.8608 | 0.8729 | 0.0000 | 0.0038 | 0.0000 | 0.0028 | 0.0000 | 0.0066 | 0.0154 | 0.0227 | 0.0292 | 0.0360 | 0.0382 | 0.0588 | 0.0544 | 0.0682 | 0.1072 | 0.0986 | 0.7555 | 0.7024 | 0.0007 | 0.0007 | 0.0029 | 0.0059 | 0.0192 | 0.0354 | 0.0347 | 0.0560 | 0.8444 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 735 | 770 | | 6091 | 18694 | 277.5 | 59.08 | 146.13 | 189.54 | 207 | 227 | 242 | 257 | 270 | 286 | 303 | 325 | 360 | 0.0517 | 966 | 1.132 | 134.38 | 47.43 | 1 | 0.0545 | 332 | 0.0007 | 64.70 | 7.464 | 0.1528 | 80490.5 | 24400000 | 7720000000 | 2550000000000 | 0.4323 | 0.2199 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0000 | 0.0154 | 0.0014 | 0.0654 | 0.0175 | 0.1429 | 0.0415 | 0.1509 | 0.0382 | 0.1728 | 0.0693 | 0.4499 | 0.8321 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0079 | 0.0003 | 0.0304 | 0.0134 | 0.0630 | 0.0205 | 0.0642 | 0.0152 | 0.0902 | 0.0304 | 0.7430 | 0.9203 | 0.0019 | 0.0132 | 0.0096 | 0.0166 | 0.0182 | 0.0795 | 0.0738 | 0.1358 | 0.1381 | 0.1821 | 0.1937 | 0.2318 | 0.1035 | 0.0762 | 0.1505 | 0.1126 | 0.3106 | 0.1523 | 0.0018 | 0.0033 | 0.0109 | 0.0301 | 0.0733 | 0.1309 | 0.1099 | 0.1193 | 0.5205 | 9 | 11 | 12 | 15 | 30 | 105 | 203 | 301 | 416 | 0.1325 | 29.91 | 4.805 | 0.5468 | 57276.7 | 29800000 | 18600000000 | 13400000000000 | 0.5440 | 0.1256 | 0.0714 | 0.0031 | 0.2395 | 0.0243 | 0.3145 | 0.1494 | 0.1559 | 0.2050 | 0.1263 | 0.2205 | 0.0462 | 0.1803 | 0.0314 | 0.0985 | 0.0096 | 0.0681 | 0.0052 | 0.0508 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0006 | 0.0006 | 0.0059 | 0.0032 | 0.0420 | 0.0353 | 0.0761 | 0.0653 | 0.0627 | 0.0511 | 0.0960 | 0.0756 | 0.7167 | 0.7688 | 0.0002 | 0.0000 | 0.0007 | 0.0009 | 0.0015 | 0.0021 | 0.0100 | 0.0122 | 0.0607 | 0.0697 | 0.1088 | 0.1264 | 0.0830 | 0.0840 | 0.1178 | 0.1284 | 0.6173 | 0.5762 | 0.0000 | 0.0004 | 0.0006 | 0.0073 | 0.0536 | 0.0927 | 0.0730 | 0.1036 | 0.6688 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 199 | 260 | | 10686 | 24087 | 343.1 | 42.34 | 218.62 | 243.80 | 294 | 309 | 319 | 329 | 339 | 349 | 361 | 376 | 398 | 0.0560 | 1348 | 1.108 | 80.65 | 27.02 | 2 | 0.0188 | 201 | 0.0020 | 20.94 | 6.553 | 0.2495 | 119532.0 | 42300000 | 15200000000 | 5550000000000 | 0.4430 | 0.2105 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0032 | 0.0005 | 0.0194 | 0.0089 | 0.0355 | 0.0176 | 0.0461 | 0.0113 | 0.0755 | 0.0211 | 0.8188 | 0.9407 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0015 | 0.0000 | 0.0114 | 0.0086 | 0.0212 | 0.0159 | 0.0232 | 0.0077 | 0.0352 | 0.0146 | 0.9074 | 0.9532 | 0.0199 | 0.0000 | 0.0385 | 0.0000 | 0.0442 | 0.0000 | 0.0855 | 0.0000 | 0.0954 | 0.0000 | 0.1311 | 0.0000 | 0.1197 | 0.0000 | 0.1211 | 0.0000 | 0.3447 | 0.0000 | 0.0047 | 0.0098 | 0.0155 | 0.0422 | 0.0674 | 0.0986 | 0.1131 | 0.1277 | 0.5211 | 18 | 23 | 29 | 46 | 110 | 198 | 297 | 422 | 589 | 0.0307 | 46.12 | 5.951 | 0.4302 | 107227.0 | 68300000 | 50200000000 | 40800000000000 | 0.5298 | 0.1259 | 0.0245 | 0.0018 | 0.1127 | 0.0149 | 0.2277 | 0.0610 | 0.1750 | 0.0972 | 0.1550 | 0.1809 | 0.1245 | 0.2068 | 0.0732 | 0.1277 | 0.0609 | 0.1204 | 0.0464 | 0.1894 | 0.0000 | 0.0000 | 0.0005 | 0.0002 | 0.0017 | 0.0016 | 0.0077 | 0.0073 | 0.0415 | 0.0338 | 0.0707 | 0.0588 | 0.0495 | 0.0417 | 0.0772 | 0.0625 | 0.7513 | 0.7941 | 0.0004 | 0.0004 | 0.0010 | 0.0016 | 0.0029 | 0.0041 | 0.0139 | 0.0205 | 0.0578 | 0.0653 | 0.0903 | 0.1105 | 0.0763 | 0.0890 | 0.1087 | 0.1110 | 0.6487 | 0.5975 | 0.0001 | 0.0011 | 0.0034 | 0.0105 | 0.0471 | 0.0826 | 0.0615 | 0.0887 | 0.7050 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 933 | 214 | | 5101 | 5870 | 110.2 | 27.49 | 259.56 | 186.24 | 81 | 88 | 94 | 100 | 106 | 112 | 119 | 129 | 146 | 0.1181 | 693 | 0.954 | 104.01 | 27.86 | 1 | 0.0514 | 262 | 0.0033 | 15.83 | 6.117 | 0.2885 | 12892.3 | 1610000 | 215000000 | 30600000000 | 0.4365 | 0.2174 | 0.0000 | 0.0000 | 0.0034 | 0.0000 | 0.0103 | 0.0002 | 0.0327 | 0.0041 | 0.0791 | 0.0237 | 0.1405 | 0.0507 | 0.1464 | 0.0487 | 0.1803 | 0.0643 | 0.4074 | 0.8083 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0027 | 0.0000 | 0.0133 | 0.0010 | 0.0360 | 0.0143 | 0.0691 | 0.0261 | 0.0718 | 0.0191 | 0.1049 | 0.0323 | 0.7006 | 0.9072 | 0.0043 | 0.0000 | 0.0076 | 0.0104 | 0.0205 | 0.0286 | 0.0777 | 0.1042 | 0.1295 | 0.1823 | 0.1672 | 0.2031 | 0.1176 | 0.0964 | 0.1316 | 0.1406 | 0.3441 | 0.2344 | 0.0009 | 0.0045 | 0.0190 | 0.0407 | 0.0945 | 0.1392 | 0.1062 | 0.1456 | 0.4494 | 32 | 73 | 127 | 182 | 237 | 290 | 350 | 422 | 519 | 0.0019 | 77.87 | 7.288 | 0.2207 | 102053.0 | 48600000 | 26200000000 | 15400000000000 | 0.5763 | 0.1260 | 0.0142 | 0.0028 | 0.0809 | 0.0120 | 0.1813 | 0.0384 | 0.2018 | 0.0791 | 0.1947 | 0.1512 | 0.1493 | 0.1883 | 0.1084 | 0.1684 | 0.0516 | 0.1489 | 0.0178 | 0.2109 | 0.0003 | 0.0003 | 0.0018 | 0.0013 | 0.0055 | 0.0029 | 0.0160 | 0.0108 | 0.0674 | 0.0567 | 0.1167 | 0.0966 | 0.0890 | 0.0764 | 0.1290 | 0.1066 | 0.5743 | 0.6484 | 0.0014 | 0.0036 | 0.0019 | 0.0006 | 0.0113 | 0.0164 | 0.0386 | 0.0498 | 0.1050 | 0.1343 | 0.1671 | 0.1926 | 0.1266 | 0.1179 | 0.1558 | 0.1422 | 0.3922 | 0.3426 | 0.0000 | 0.0033 | 0.0052 | 0.0298 | 0.0818 | 0.1369 | 0.1153 | 0.1447 | 0.4829 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 270 | 814 | | 2851 | 8407 | 391.9 | 153.08 | 40.60 | 64.74 | 211 | 237 | 264 | 302 | 359 | 440 | 510 | 564 | 609 | 0.0793 | 667 | 0.638 | 88.07 | 16.49 | 5 | 0.0831 | 237 | 0.0014 | 33.60 | 6.853 | 0.2650 | 176986.0 | 88700000 | 47600000000 | 26700000000000 | 0.3694 | 0.2467 | 0.0017 | 0.0000 | 0.0000 | 0.0018 | 0.0198 | 0.0037 | 0.0594 | 0.0117 | 0.2228 | 0.0608 | 0.2475 | 0.1148 | 0.1320 | 0.0853 | 0.1254 | 0.1160 | 0.1914 | 0.6059 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0004 | 0.0061 | 0.0056 | 0.0386 | 0.0265 | 0.0570 | 0.0521 | 0.0404 | 0.0348 | 0.0545 | 0.0465 | 0.8009 | 0.8341 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0019 | 0.0059 | 0.0049 | 0.0208 | 0.0507 | 0.0639 | 0.0789 | 0.0906 | 0.0478 | 0.0743 | 0.0741 | 0.1055 | 0.7417 | 0.6360 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0430 | 0.0675 | 0.0453 | 0.0606 | 0.7782 | 8 | 10 | 11 | 13 | 15 | 18 | 24 | 42 | 117 | 0.0814 | 2.85 | 3.639 | 0.6573 | 5839.4 | 1330000 | 353000000 | 100000000000 | 0.5410 | 0.1261 | 0.0144 | 0.0101 | 0.0804 | 0.0340 | 0.1835 | 0.0451 | 0.1773 | 0.0975 | 0.1567 | 0.1408 | 0.1649 | 0.1638 | 0.1113 | 0.1408 | 0.0804 | 0.1435 | 0.0309 | 0.2245 | 0.0015 | 0.0040 | 0.0060 | 0.0136 | 0.0144 | 0.0100 | 0.0194 | 0.0244 | 0.0557 | 0.0505 | 0.0815 | 0.0765 | 0.0532 | 0.0589 | 0.0820 | 0.0885 | 0.6864 | 0.6735 | 0.0000 | 0.0000 | 0.0013 | 0.0007 | 0.0033 | 0.0050 | 0.0196 | 0.0177 | 0.0629 | 0.0703 | 0.0812 | 0.0809 | 0.0583 | 0.0596 | 0.0799 | 0.0852 | 0.6935 | 0.6806 | 0.0034 | 0.0040 | 0.0017 | 0.0166 | 0.0625 | 0.0763 | 0.0539 | 0.0878 | 0.6936 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1163 | 914 | | 2848 | 4080 | 128.2 | 26.29 | 72.09 | 52.48 | 98 | 106 | 112 | 118 | 124 | 131 | 140 | 151 | 166 | 0.1199 | 489 | 1.053 | 105.55 | 34.18 | 1 | 0.0952 | 271 | 0.0016 | 34.35 | 6.710 | 0.2008 | 17134.3 | 2390000 | 346000000 | 52000000000 | 0.4596 | 0.1985 | 0.0005 | 0.0000 | 0.0026 | 0.0000 | 0.0083 | 0.0011 | 0.0365 | 0.0033 | 0.0813 | 0.0228 | 0.1370 | 0.0538 | 0.1370 | 0.0435 | 0.1917 | 0.0748 | 0.4052 | 0.8007 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0021 | 0.0004 | 0.0153 | 0.0004 | 0.0425 | 0.0148 | 0.0689 | 0.0445 | 0.0669 | 0.0169 | 0.1102 | 0.0342 | 0.6929 | 0.8889 | 0.0060 | 0.0252 | 0.0099 | 0.0672 | 0.0298 | 0.0756 | 0.0736 | 0.2521 | 0.1650 | 0.2017 | 0.2107 | 0.1513 | 0.1233 | 0.0924 | 0.1551 | 0.1008 | 0.2266 | 0.0336 | 0.0031 | 0.0039 | 0.0164 | 0.0374 | 0.0997 | 0.1394 | 0.1012 | 0.1355 | 0.4634 | 25 | 34 | 43 | 51 | 59 | 69 | 81 | 99 | 131 | 0.0231 | 3.25 | 4.328 | 0.5781 | 7950.5 | 1300000 | 290000000 | 79400000000 | 0.5593 | 0.1262 | 0.0086 | 0.0015 | 0.0574 | 0.0068 | 0.1463 | 0.0181 | 0.1663 | 0.0556 | 0.1740 | 0.1171 | 0.1463 | 0.1679 | 0.1205 | 0.1445 | 0.1052 | 0.1723 | 0.0755 | 0.3163 | 0.0019 | 0.0011 | 0.0057 | 0.0032 | 0.0127 | 0.0081 | 0.0340 | 0.0218 | 0.0816 | 0.0567 | 0.1108 | 0.0820 | 0.1066 | 0.0753 | 0.1472 | 0.1137 | 0.4995 | 0.6383 | 0.0028 | 0.0063 | 0.0084 | 0.0063 | 0.0307 | 0.0378 | 0.0568 | 0.0908 | 0.1331 | 0.1311 | 0.1695 | 0.1702 | 0.1089 | 0.1059 | 0.1406 | 0.1248 | 0.3492 | 0.3266 | 0.0071 | 0.0065 | 0.0162 | 0.0518 | 0.0945 | 0.1579 | 0.1204 | 0.1379 | 0.4078 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 472 | 365 | | 10152 | 16333 | 306.6 | 57.54 | 224.30 | 196.37 | 237 | 256 | 271 | 285 | 301 | 317 | 336 | 357 | 386 | 0.0678 | 1107 | 0.822 | 136.62 | 44.05 | 1 | 0.0396 | 402 | 0.0006 | 77.66 | 7.651 | 0.1416 | 97320.9 | 31900000 | 10800000000 | 3780000000000 | 0.4559 | 0.2016 | 0.0007 | 0.0000 | 0.0006 | 0.0000 | 0.0038 | 0.0001 | 0.0147 | 0.0006 | 0.0559 | 0.0105 | 0.1218 | 0.0272 | 0.1337 | 0.0260 | 0.1584 | 0.0428 | 0.5103 | 0.8928 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0036 | 0.0001 | 0.0257 | 0.0079 | 0.0578 | 0.0184 | 0.0582 | 0.0109 | 0.0841 | 0.0197 | 0.7693 | 0.9430 | 0.0025 | 0.0159 | 0.0101 | 0.0518 | 0.0297 | 0.0876 | 0.0802 | 0.2072 | 0.1723 | 0.1952 | 0.1799 | 0.1474 | 0.1187 | 0.1036 | 0.1503 | 0.0558 | 0.2563 | 0.1355 | 0.0008 | 0.0025 | 0.0127 | 0.0317 | 0.0909 | 0.1254 | 0.1094 | 0.1379 | 0.4885 | 22 | 46 | 83 | 125 | 173 | 229 | 295 | 376 | 500 | 0.0068 | 69.26 | 6.886 | 0.2834 | 88869.9 | 46400000 | 29000000000 | 20500000000000 | 0.5451 | 0.1262 | 0.0275 | 0.0020 | 0.1405 | 0.0066 | 0.2540 | 0.0553 | 0.1753 | 0.1106 | 0.1531 | 0.1890 | 0.1086 | 0.2034 | 0.0715 | 0.1379 | 0.0376 | 0.1361 | 0.0319 | 0.1591 | 0.0004 | 0.0006 | 0.0004 | 0.0007 | 0.0035 | 0.0023 | 0.0163 | 0.0094 | 0.0680 | 0.0540 | 0.1119 | 0.0867 | 0.0864 | 0.0698 | 0.1192 | 0.1056 | 0.5940 | 0.6708 | 0.0002 | 0.0013 | 0.0020 | 0.0036 | 0.0087 | 0.0107 | 0.0296 | 0.0330 | 0.1018 | 0.1162 | 0.1498 | 0.1759 | 0.1073 | 0.1119 | 0.1433 | 0.1478 | 0.4572 | 0.3996 | 0.0004 | 0.0016 | 0.0045 | 0.0181 | 0.0879 | 0.1310 | 0.0994 | 0.1385 | 0.5186 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 564 | 431 | | 338 | 1164 | 102.2 | 15.22 | 7.58 | 3.30 | 84 | 88 | 92 | 95 | 102 | 108 | 112 | 115 | 121 | 0.2259 | 263 | 0.523 | 92.70 | 19.72 | 2 | 0.8195 | 277 | 0.0741 | 0.65 | 2.916 | 0.7228 | 10676.7 | 1140000 | 124000000 | 13800000000 | 0.3677 | 0.2665 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0035 | 0.0000 | 0.0070 | 0.0090 | 0.0662 | 0.0448 | 0.1533 | 0.0985 | 0.0732 | 0.0507 | 0.1150 | 0.0836 | 0.5784 | 0.7134 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0063 | 0.0089 | 0.0508 | 0.0444 | 0.1111 | 0.0947 | 0.0381 | 0.0385 | 0.0730 | 0.0621 | 0.7175 | 0.7515 | 0.0000 | 0.0000 | 0.0357 | 0.0000 | 0.0357 | 1.0000 | 0.1071 | 0.0000 | 0.1786 | 0.0000 | 0.1786 | 0.0000 | 0.1429 | 0.0000 | 0.1071 | 0.0000 | 0.2143 | 0.0000 | 0.0059 | 0.0000 | 0.0000 | 0.0296 | 0.0710 | 0.0888 | 0.0888 | 0.0947 | 0.6213 | 5 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 10 | 0.1160 | 0.40 | 1.049 | 0.4095 | 68.4 | 808.275 | 13870.1 | 338018 | 0.5218 | 0.1263 | 0.0138 | 0.0000 | 0.1041 | 0.0030 | 0.2004 | 0.0099 | 0.2338 | 0.0338 | 0.1847 | 0.0746 | 0.1493 | 0.1014 | 0.0727 | 0.1690 | 0.0393 | 0.3052 | 0.0020 | 0.3032 | 0.0071 | 0.0000 | 0.0454 | 0.0000 | 0.0894 | 0.0055 | 0.1504 | 0.0193 | 0.1660 | 0.0654 | 0.1943 | 0.1096 | 0.1191 | 0.1436 | 0.1121 | 0.2818 | 0.1163 | 0.3748 | 0.2041 | 0.0875 | 0.1735 | 0.1250 | 0.0561 | 0.1250 | 0.0765 | 0.0500 | 0.1173 | 0.0625 | 0.1276 | 0.1750 | 0.0918 | 0.1625 | 0.0918 | 0.1000 | 0.0612 | 0.1125 | 0.0463 | 0.1305 | 0.1347 | 0.1705 | 0.1347 | 0.1200 | 0.0968 | 0.0758 | 0.0905 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 502 | 891 | | 697 | 2813 | 320.4 | 207.81 | 13.17 | 5.09 | 98 | 125 | 170 | 212 | 264 | 326 | 402 | 514 | 669 | 0.1337 | 376 | 1.160 | 26.25 | 8.00 | 2 | 0.0918 | 64 | 0.0019 | 99.20 | 6.369 | 0.1311 | 145754.0 | 81100000 | 50300000000 | 33200000000000 | 0.2968 | 0.3295 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0303 | 0.0000 | 0.0909 | 0.0036 | 0.2348 | 0.1155 | 0.2348 | 0.1769 | 0.2273 | 0.1227 | 0.1288 | 0.1444 | 0.0530 | 0.4368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0084 | 0.0022 | 0.0503 | 0.0508 | 0.0670 | 0.0640 | 0.0475 | 0.0375 | 0.0587 | 0.0486 | 0.7682 | 0.7969 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0133 | 0.0114 | 0.0487 | 0.0739 | 0.1062 | 0.0966 | 0.0442 | 0.0568 | 0.0752 | 0.0852 | 0.7124 | 0.6761 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0565 | 0.0919 | 0.0389 | 0.0671 | 0.7420 | 7 | 9 | 10 | 12 | 13 | 14 | 15 | 17 | 20 | 0.4201 | 0.26 | 1.281 | 0.8672 | 199.4 | 3414.53 | 65866.6 | 1430000 | 0.5670 | 0.1264 | 0.0375 | 0.0039 | 0.0586 | 0.0218 | 0.0980 | 0.0262 | 0.1548 | 0.0510 | 0.1951 | 0.0694 | 0.2070 | 0.0879 | 0.1712 | 0.1422 | 0.0678 | 0.2146 | 0.0101 | 0.3830 | 0.0136 | 0.0020 | 0.0172 | 0.0131 | 0.0183 | 0.0127 | 0.0365 | 0.0295 | 0.0662 | 0.0516 | 0.0986 | 0.0540 | 0.1377 | 0.0704 | 0.2165 | 0.1101 | 0.3954 | 0.6566 | 0.0545 | 0.0966 | 0.0703 | 0.0914 | 0.0812 | 0.0914 | 0.1018 | 0.1227 | 0.1115 | 0.1488 | 0.1236 | 0.1488 | 0.1164 | 0.1175 | 0.1794 | 0.1071 | 0.1612 | 0.0757 | 0.0122 | 0.0278 | 0.0523 | 0.0733 | 0.1025 | 0.1263 | 0.1514 | 0.1826 | 0.2716 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1049 | 621 | | 590 | 4448 | 85.8 | 21.32 | 144.11 | 133.60 | 56 | 64 | 73 | 81 | 87 | 93 | 99 | 106 | 114 | 0.1034 | 460 | 0.497 | 89.47 | 17.12 | 2 | 0.4254 | 251 | 0.0059 | 8.91 | 5.340 | 0.3127 | 7819.9 | 748619 | 74600000 | 7680000000 | 0.5406 | 0.1228 | 0.0066 | 0.0000 | 0.0197 | 0.0037 | 0.0656 | 0.0019 | 0.1016 | 0.0335 | 0.1311 | 0.0764 | 0.2557 | 0.1676 | 0.1213 | 0.0950 | 0.1279 | 0.1639 | 0.1705 | 0.4581 | 0.0000 | 0.0000 | 0.0023 | 0.0018 | 0.0023 | 0.0018 | 0.0227 | 0.0161 | 0.0975 | 0.0698 | 0.2245 | 0.1592 | 0.0998 | 0.0823 | 0.1678 | 0.1485 | 0.3832 | 0.5206 | 0.0000 | 0.0000 | 0.0074 | 0.0909 | 0.0662 | 0.1818 | 0.1103 | 0.2273 | 0.1838 | 0.3636 | 0.2721 | 0.0455 | 0.1176 | 0.0909 | 0.0809 | 0.0000 | 0.1618 | 0.0000 | 0.0032 | 0.0130 | 0.0260 | 0.0747 | 0.1494 | 0.1851 | 0.1071 | 0.1558 | 0.2857 | 25 | 39 | 55 | 74 | 98 | 130 | 170 | 228 | 340 | 0.0100 | 16.93 | 5.669 | 0.4305 | 38612.5 | 14500000 | 6620000000 | 3390000000000 | 0.5378 | 0.1265 | 0.0156 | 0.0023 | 0.0845 | 0.0068 | 0.1831 | 0.0288 | 0.1815 | 0.0788 | 0.1800 | 0.1455 | 0.1315 | 0.1856 | 0.0767 | 0.1667 | 0.0610 | 0.1439 | 0.0861 | 0.2417 | 0.0010 | 0.0013 | 0.0036 | 0.0025 | 0.0051 | 0.0033 | 0.0159 | 0.0134 | 0.0568 | 0.0473 | 0.0967 | 0.0854 | 0.0747 | 0.0703 | 0.0988 | 0.1000 | 0.6474 | 0.6766 | 0.0000 | 0.0037 | 0.0038 | 0.0019 | 0.0198 | 0.0131 | 0.0243 | 0.0411 | 0.0654 | 0.0626 | 0.1209 | 0.1280 | 0.0928 | 0.0888 | 0.1042 | 0.1271 | 0.5688 | 0.5336 | 0.0006 | 0.0000 | 0.0112 | 0.0262 | 0.0611 | 0.1185 | 0.0855 | 0.1017 | 0.5951 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 351 | 817 | | 9511 | 24722 | 663.7 | 127.78 | 143.84 | 120.28 | 511 | 554 | 590 | 622 | 652 | 682 | 719 | 762 | 832 | 0.0415 | 1026 | 1.074 | 119.25 | 34.18 | 1 | 0.0296 | 282 | 0.0006 | 68.98 | 7.664 | 0.1441 | 456877.0 | 326000000 | 242000000000 | 186000000000000 | 0.4519 | 0.1968 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0094 | 0.0009 | 0.0457 | 0.0134 | 0.1036 | 0.0254 | 0.1111 | 0.0244 | 0.1527 | 0.0381 | 0.5755 | 0.8977 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0045 | 0.0000 | 0.0248 | 0.0094 | 0.0491 | 0.0164 | 0.0529 | 0.0124 | 0.0765 | 0.0208 | 0.7912 | 0.9411 | 0.0059 | 0.0087 | 0.0117 | 0.0145 | 0.0257 | 0.0378 | 0.0638 | 0.0698 | 0.1136 | 0.1337 | 0.1730 | 0.1890 | 0.0916 | 0.1105 | 0.1239 | 0.1570 | 0.3908 | 0.2791 | 0.0014 | 0.0027 | 0.0105 | 0.0302 | 0.0743 | 0.1243 | 0.1152 | 0.1353 | 0.5061 | 25 | 41 | 62 | 89 | 117 | 146 | 179 | 221 | 297 | 0.0086 | 17.29 | 5.757 | 0.3844 | 35156.3 | 12300000 | 5720000000 | 3420000000000 | 0.5257 | 0.1266 | 0.0343 | 0.0013 | 0.1241 | 0.0069 | 0.2250 | 0.0632 | 0.1641 | 0.1106 | 0.1554 | 0.1604 | 0.1191 | 0.1950 | 0.0806 | 0.1372 | 0.0561 | 0.1368 | 0.0413 | 0.1885 | 0.0002 | 0.0001 | 0.0011 | 0.0008 | 0.0035 | 0.0022 | 0.0199 | 0.0132 | 0.0765 | 0.0573 | 0.1252 | 0.1004 | 0.0980 | 0.0781 | 0.1344 | 0.1169 | 0.5411 | 0.6309 | 0.0025 | 0.0037 | 0.0041 | 0.0075 | 0.0118 | 0.0181 | 0.0405 | 0.0553 | 0.1145 | 0.1217 | 0.1629 | 0.1803 | 0.1285 | 0.1332 | 0.1493 | 0.1508 | 0.3858 | 0.3294 | 0.0009 | 0.0029 | 0.0080 | 0.0298 | 0.0939 | 0.1493 | 0.1124 | 0.1501 | 0.4528 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1048 | 708 | | 5142 | 24738 | 301.9 | 68.07 | 109.84 | 172.01 | 222 | 242 | 260 | 277 | 294 | 311 | 331 | 357 | 392 | 0.0388 | 959 | 0.968 | 116.28 | 25.18 | 1 | 0.0492 | 253 | 0.0006 | 71.96 | 7.550 | 0.1408 | 95756.4 | 31900000 | 11200000000 | 4100000000000 | 0.4570 | 0.1935 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0047 | 0.0000 | 0.0216 | 0.0019 | 0.0748 | 0.0214 | 0.1430 | 0.0387 | 0.1596 | 0.0406 | 0.1790 | 0.0601 | 0.4156 | 0.8373 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0000 | 0.0082 | 0.0000 | 0.0378 | 0.0149 | 0.0692 | 0.0253 | 0.0736 | 0.0188 | 0.0862 | 0.0339 | 0.7226 | 0.9070 | 0.0043 | 0.0069 | 0.0096 | 0.0069 | 0.0246 | 0.0138 | 0.0769 | 0.0897 | 0.1143 | 0.1655 | 0.1357 | 0.1483 | 0.1026 | 0.1621 | 0.1303 | 0.1345 | 0.4017 | 0.2724 | 0.0009 | 0.0009 | 0.0082 | 0.0359 | 0.0848 | 0.1107 | 0.1086 | 0.1302 | 0.5199 | 8 | 9 | 10 | 12 | 15 | 23 | 92 | 222 | 376 | 0.2071 | 21.28 | 4.079 | 0.6284 | 41652.0 | 21000000 | 12200000000 | 7930000000000 | 0.5079 | 0.1266 | 0.0955 | 0.0067 | 0.2888 | 0.0516 | 0.2966 | 0.2331 | 0.1382 | 0.1992 | 0.0843 | 0.1815 | 0.0618 | 0.1415 | 0.0247 | 0.0705 | 0.0079 | 0.0494 | 0.0022 | 0.0666 | 0.0000 | 0.0001 | 0.0005 | 0.0000 | 0.0009 | 0.0007 | 0.0081 | 0.0081 | 0.0426 | 0.0385 | 0.0742 | 0.0621 | 0.0481 | 0.0470 | 0.0763 | 0.0643 | 0.7492 | 0.7792 | 0.0003 | 0.0005 | 0.0011 | 0.0016 | 0.0032 | 0.0042 | 0.0113 | 0.0130 | 0.0493 | 0.0504 | 0.0852 | 0.0895 | 0.0569 | 0.0606 | 0.0833 | 0.0935 | 0.7095 | 0.6868 | 0.0003 | 0.0007 | 0.0018 | 0.0119 | 0.0426 | 0.0802 | 0.0555 | 0.0798 | 0.7272 |
| SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 451 | | 11232 | 18145 | 198.9 | 80.62 | 6.13 | 2.92 | 96 | 118 | 138 | 163 | 190 | 224 | 254 | 281 | 308 | 0.0881 | 1598 | 0.402 | 135.09 | 20.03 | 6 | 0.0363 | 408 | 0.0017 | 7.54 | 6.630 | 0.3605 | 46068.3 | 11900000 | 3280000000 | 953000000000 | 0.4257 | 0.1921 | 0.0034 | 0.0015 | 0.0058 | 0.0030 | 0.0089 | 0.0074 | 0.0294 | 0.0164 | 0.0684 | 0.0406 | 0.1042 | 0.0619 | 0.1097 | 0.0584 | 0.1415 | 0.0780 | 0.5287 | 0.7328 | 0.0006 | 0.0003 | 0.0010 | 0.0001 | 0.0022 | 0.0029 | 0.0064 | 0.0067 | 0.0146 | 0.0168 | 0.0254 | 0.0283 | 0.0235 | 0.0230 | 0.0296 | 0.0320 | 0.8967 | 0.8898 | 0.0005 | 0.0025 | 0.0033 | 0.0051 | 0.0060 | 0.0132 | 0.0098 | 0.0229 | 0.0280 | 0.0467 | 0.0282 | 0.0642 | 0.0358 | 0.0778 | 0.0499 | 0.0999 | 0.8385 | 0.6677 | 0.0009 | 0.0007 | 0.0024 | 0.0073 | 0.0189 | 0.0239 | 0.0284 | 0.0375 | 0.8799 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.1305 | 0.44 | 1.002 | 0.4054 | 46.1 | 458.785 | 7687.85 | 234458 | 0.5483 | 0.1268 | 0.0123 | 0.0015 | 0.0555 | 0.0107 | 0.1399 | 0.0297 | 0.2151 | 0.0734 | 0.2476 | 0.1533 | 0.1919 | 0.2308 | 0.1031 | 0.2579 | 0.0306 | 0.1797 | 0.0042 | 0.0631 | 0.0008 | 0.0001 | 0.0083 | 0.0014 | 0.0270 | 0.0074 | 0.0633 | 0.0263 | 0.1189 | 0.0658 | 0.1643 | 0.1156 | 0.2017 | 0.2003 | 0.2201 | 0.2840 | 0.1956 | 0.2992 | 0.1197 | 0.2233 | 0.1816 | 0.2100 | 0.1733 | 0.1903 | 0.1579 | 0.1256 | 0.1231 | 0.0803 | 0.0916 | 0.0538 | 0.0625 | 0.0439 | 0.0525 | 0.0381 | 0.0379 | 0.0347 | 0.0066 | 0.0454 | 0.0962 | 0.1383 | 0.1787 | 0.1873 | 0.1512 | 0.1164 | 0.0797 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 409 | 890 | | 816 | 11183 | 89.7 | 9.29 | 105.45 | 153.75 | 78 | 81 | 84 | 87 | 90 | 92 | 95 | 98 | 101 | 0.0640 | 716 | 0.688 | 118.34 | 30.02 | 4 | 0.4142 | 338 | 0.0250 | 2.26 | 3.936 | 0.5414 | 8132.4 | 745123 | 69000000 | 6450000000 | 0.4240 | 0.2141 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0038 | 0.0012 | 0.0166 | 0.0086 | 0.0422 | 0.0319 | 0.0575 | 0.0564 | 0.0665 | 0.0380 | 0.1151 | 0.0576 | 0.6982 | 0.8064 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0012 | 0.0137 | 0.0086 | 0.0373 | 0.0319 | 0.0460 | 0.0564 | 0.0522 | 0.0380 | 0.0646 | 0.0576 | 0.7826 | 0.8064 | 0.1304 | 0.0000 | 0.0870 | 0.0000 | 0.0870 | 0.0000 | 0.2174 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.0870 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0048 | 0.0096 | 0.0265 | 0.0265 | 0.0964 | 0.1084 | 0.1084 | 0.1880 | 0.4313 | 12 | 15 | 19 | 25 | 36 | 56 | 93 | 175 | 308 | 0.0583 | 19.57 | 4.627 | 0.5749 | 34757.8 | 18600000 | 13100000000 | 11000000000000 | 0.5602 | 0.1268 | 0.0620 | 0.0049 | 0.1860 | 0.0220 | 0.2709 | 0.1170 | 0.1685 | 0.1506 | 0.1119 | 0.1935 | 0.0876 | 0.1911 | 0.0539 | 0.1066 | 0.0270 | 0.0980 | 0.0323 | 0.1164 | 0.0006 | 0.0010 | 0.0025 | 0.0017 | 0.0048 | 0.0048 | 0.0202 | 0.0167 | 0.0663 | 0.0628 | 0.1003 | 0.0944 | 0.0621 | 0.0604 | 0.1056 | 0.0980 | 0.6376 | 0.6603 | 0.0011 | 0.0004 | 0.0011 | 0.0008 | 0.0032 | 0.0054 | 0.0231 | 0.0233 | 0.0774 | 0.0848 | 0.1214 | 0.1431 | 0.0781 | 0.0809 | 0.1256 | 0.1268 | 0.5692 | 0.5344 | 0.0010 | 0.0016 | 0.0058 | 0.0214 | 0.0672 | 0.1140 | 0.0643 | 0.1191 | 0.6056 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 441 | 854 | | 1964 | 2153 | 94.0 | 19.07 | 5.89 | 2.19 | 65 | 75 | 84 | 91 | 97 | 103 | 107 | 111 | 116 | 0.2216 | 477 | 0.494 | 340.58 | 73.33 | 1 | 0.5046 | 991 | 0.0224 | 1.75 | 4.105 | 0.5669 | 9205.0 | 931383 | 96800000 | 10300000000 | 0.4309 | 0.2010 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0147 | 0.0005 | 0.0359 | 0.0058 | 0.0661 | 0.0242 | 0.1184 | 0.0453 | 0.1380 | 0.0353 | 0.1959 | 0.0679 | 0.4237 | 0.8211 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0013 | 0.0005 | 0.0109 | 0.0052 | 0.0300 | 0.0235 | 0.0504 | 0.0434 | 0.0549 | 0.0314 | 0.0709 | 0.0581 | 0.7797 | 0.8378 | 0.0235 | 0.0909 | 0.0293 | 0.0000 | 0.0704 | 0.1818 | 0.1056 | 0.0909 | 0.1144 | 0.3636 | 0.1525 | 0.2727 | 0.1290 | 0.0000 | 0.1290 | 0.0000 | 0.2463 | 0.0000 | 0.0000 | 0.0027 | 0.0045 | 0.0163 | 0.0506 | 0.0624 | 0.0678 | 0.0850 | 0.7107 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.5417 | 0.29 | 0.926 | 0.8524 | 39.5 | 290.243 | 2305.17 | 19573.6 | 0.5333 | 0.1268 | 0.0126 | 0.0006 | 0.0816 | 0.0054 | 0.1641 | 0.0320 | 0.2592 | 0.0633 | 0.2505 | 0.1333 | 0.1534 | 0.1960 | 0.0621 | 0.2340 | 0.0155 | 0.2117 | 0.0010 | 0.1236 | 0.0000 | 0.0000 | 0.0139 | 0.0011 | 0.0357 | 0.0096 | 0.1130 | 0.0340 | 0.1897 | 0.0919 | 0.2161 | 0.1338 | 0.2254 | 0.1875 | 0.1586 | 0.2953 | 0.0476 | 0.2469 | 0.1946 | 0.4222 | 0.2754 | 0.2667 | 0.2402 | 0.1378 | 0.1718 | 0.1244 | 0.0787 | 0.0400 | 0.0311 | 0.0089 | 0.0062 | 0.0000 | 0.0021 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0552 | 0.1027 | 0.1986 | 0.2182 | 0.1910 | 0.1171 | 0.0849 | 0.0246 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 919 | 347 | | 5602 | 6122 | 469.4 | 79.21 | 27.49 | 47.62 | 357 | 396 | 427 | 455 | 479 | 496 | 513 | 531 | 559 | 0.1042 | 638 | 0.998 | 133.18 | 37.86 | 1 | 0.0605 | 339 | 0.0017 | 16.11 | 6.642 | 0.3084 | 226643.0 | 112000000 | 57000000000 | 29500000000000 | 0.4201 | 0.2305 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0000 | 0.0068 | 0.0007 | 0.0224 | 0.0104 | 0.0352 | 0.0294 | 0.0373 | 0.0137 | 0.0623 | 0.0225 | 0.8308 | 0.9233 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0025 | 0.0000 | 0.0042 | 0.0005 | 0.0136 | 0.0097 | 0.0247 | 0.0272 | 0.0207 | 0.0098 | 0.0262 | 0.0177 | 0.9067 | 0.9351 | 0.0187 | 0.0000 | 0.0093 | 0.0541 | 0.0093 | 0.0811 | 0.0318 | 0.1622 | 0.0486 | 0.1892 | 0.0542 | 0.1892 | 0.0710 | 0.0811 | 0.0841 | 0.1351 | 0.6729 | 0.1081 | 0.0000 | 0.0020 | 0.0049 | 0.0120 | 0.0273 | 0.0462 | 0.0524 | 0.0908 | 0.7645 | 8 | 10 | 12 | 14 | 15 | 17 | 20 | 29 | 50 | 0.3237 | 1.45 | 2.056 | 0.8309 | 3023.4 | 1020000 | 532000000 | 337000000000 | 0.5358 | 0.1270 | 0.0965 | 0.0392 | 0.0856 | 0.0530 | 0.0911 | 0.0723 | 0.1111 | 0.0933 | 0.1840 | 0.1154 | 0.1858 | 0.1198 | 0.1056 | 0.1375 | 0.1093 | 0.1452 | 0.0310 | 0.2242 | 0.0300 | 0.0239 | 0.0257 | 0.0316 | 0.0178 | 0.0421 | 0.0165 | 0.0541 | 0.0484 | 0.0733 | 0.0772 | 0.0824 | 0.0502 | 0.0798 | 0.0876 | 0.0900 | 0.6467 | 0.5229 | 0.0018 | 0.0011 | 0.0092 | 0.0063 | 0.0111 | 0.0138 | 0.0129 | 0.0180 | 0.0563 | 0.0624 | 0.0969 | 0.0963 | 0.0572 | 0.0709 | 0.0895 | 0.1270 | 0.6651 | 0.6042 | 0.0092 | 0.0077 | 0.0061 | 0.0146 | 0.0452 | 0.0958 | 0.0598 | 0.0782 | 0.6835 | ||
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 430 | | 9439 | 30387 | 187.6 | 49.18 | 85.43 | 137.20 | 127 | 150 | 163 | 176 | 187 | 199 | 211 | 226 | 249 | 0.0448 | 1360 | 0.978 | 133.06 | 44.05 | 3 | 0.0366 | 345 | 0.0011 | 36.27 | 7.174 | 0.1963 | 37625.0 | 7970000 | 1770000000 | 413000000000 | 0.4260 | 0.2189 | 0.0002 | 0.0000 | 0.0009 | 0.0001 | 0.0043 | 0.0007 | 0.0199 | 0.0027 | 0.0634 | 0.0169 | 0.1233 | 0.0399 | 0.1423 | 0.0401 | 0.1734 | 0.0580 | 0.4723 | 0.8415 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0072 | 0.0010 | 0.0225 | 0.0102 | 0.0434 | 0.0235 | 0.0516 | 0.0149 | 0.0628 | 0.0250 | 0.8102 | 0.9254 | 0.0063 | 0.0066 | 0.0083 | 0.0115 | 0.0276 | 0.0508 | 0.0683 | 0.0869 | 0.1017 | 0.1328 | 0.1424 | 0.1410 | 0.1226 | 0.1016 | 0.1346 | 0.1279 | 0.3881 | 0.3410 | 0.0009 | 0.0032 | 0.0071 | 0.0234 | 0.0626 | 0.0939 | 0.0934 | 0.1316 | 0.5841 | 10 | 12 | 14 | 16 | 20 | 29 | 62 | 140 | 267 | 0.1579 | 16.30 | 3.924 | 0.6407 | 26120.0 | 12600000 | 7750000000 | 5660000000000 | 0.5727 | 0.1271 | 0.1171 | 0.0076 | 0.2705 | 0.0420 | 0.2342 | 0.2186 | 0.1164 | 0.1757 | 0.1023 | 0.1567 | 0.0686 | 0.1384 | 0.0444 | 0.0856 | 0.0316 | 0.0752 | 0.0148 | 0.1002 | 0.0003 | 0.0005 | 0.0015 | 0.0008 | 0.0032 | 0.0031 | 0.0147 | 0.0133 | 0.0655 | 0.0528 | 0.0960 | 0.0906 | 0.0648 | 0.0549 | 0.0997 | 0.0876 | 0.6543 | 0.6964 | 0.0001 | 0.0004 | 0.0007 | 0.0004 | 0.0029 | 0.0039 | 0.0241 | 0.0258 | 0.0759 | 0.0823 | 0.1193 | 0.1295 | 0.0787 | 0.0827 | 0.1092 | 0.1138 | 0.5892 | 0.5612 | 0.0004 | 0.0010 | 0.0023 | 0.0194 | 0.0694 | 0.1084 | 0.0725 | 0.1053 | 0.6214 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 917 | 765 | | 4787 | 6025 | 134.0 | 29.36 | 199.47 | 144.31 | 101 | 111 | 117 | 124 | 130 | 137 | 145 | 154 | 168 | 0.1200 | 723 | 1.159 | 112.49 | 39.01 | 1 | 0.0570 | 273 | 0.0026 | 20.01 | 6.253 | 0.2547 | 18810.6 | 2780000 | 434000000 | 72000000000 | 0.4427 | 0.2093 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0064 | 0.0013 | 0.0155 | 0.0016 | 0.0709 | 0.0202 | 0.1267 | 0.0377 | 0.1506 | 0.0388 | 0.1815 | 0.0566 | 0.4467 | 0.8438 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0073 | 0.0004 | 0.0405 | 0.0149 | 0.0653 | 0.0246 | 0.0710 | 0.0181 | 0.0965 | 0.0305 | 0.7169 | 0.9114 | 0.0043 | 0.0000 | 0.0157 | 0.0082 | 0.0443 | 0.0286 | 0.0944 | 0.1224 | 0.1688 | 0.1510 | 0.1574 | 0.2041 | 0.0987 | 0.1102 | 0.1273 | 0.1224 | 0.2890 | 0.2531 | 0.0018 | 0.0042 | 0.0125 | 0.0365 | 0.0983 | 0.1347 | 0.1117 | 0.1440 | 0.4564 | 44 | 68 | 100 | 134 | 171 | 211 | 256 | 309 | 392 | 0.0015 | 70.67 | 7.066 | 0.2195 | 60610.6 | 23900000 | 11300000000 | 6160000000000 | 0.5305 | 0.1272 | 0.0202 | 0.0004 | 0.0960 | 0.0047 | 0.2098 | 0.0436 | 0.2030 | 0.0781 | 0.1955 | 0.1872 | 0.1348 | 0.1919 | 0.0851 | 0.1725 | 0.0447 | 0.1552 | 0.0110 | 0.1665 | 0.0006 | 0.0003 | 0.0009 | 0.0005 | 0.0019 | 0.0026 | 0.0206 | 0.0127 | 0.0768 | 0.0560 | 0.1070 | 0.0915 | 0.0989 | 0.0710 | 0.1385 | 0.1099 | 0.5548 | 0.6556 | 0.0015 | 0.0032 | 0.0064 | 0.0097 | 0.0124 | 0.0175 | 0.0500 | 0.0662 | 0.1199 | 0.1364 | 0.1640 | 0.1857 | 0.1189 | 0.1422 | 0.1690 | 0.1513 | 0.3578 | 0.2877 | 0.0008 | 0.0008 | 0.0077 | 0.0291 | 0.0926 | 0.1403 | 0.1170 | 0.1592 | 0.4525 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 779 | 772 | | 630 | 2293 | 62.2 | 11.79 | 6.82 | 2.35 | 48 | 51 | 54 | 57 | 61 | 65 | 69 | 73 | 77 | 0.1522 | 349 | 0.662 | 34.06 | 7.21 | 2 | 0.1444 | 91 | 0.0668 | 0.76 | 2.979 | 0.7113 | 4008.3 | 267309 | 18400000 | 1310000000 | 0.4337 | 0.1967 | 0.0000 | 0.0000 | 0.0115 | 0.0000 | 0.0253 | 0.0016 | 0.0484 | 0.0081 | 0.1106 | 0.0520 | 0.1521 | 0.0846 | 0.1728 | 0.0618 | 0.2166 | 0.1317 | 0.2627 | 0.6602 | 0.0000 | 0.0000 | 0.0038 | 0.0000 | 0.0075 | 0.0016 | 0.0226 | 0.0048 | 0.0658 | 0.0476 | 0.0921 | 0.0778 | 0.0714 | 0.0429 | 0.1372 | 0.0984 | 0.5996 | 0.7270 | 0.0102 | 0.1333 | 0.0408 | 0.0000 | 0.0612 | 0.1333 | 0.1633 | 0.4000 | 0.1837 | 0.0000 | 0.2245 | 0.2667 | 0.1224 | 0.0000 | 0.1020 | 0.0000 | 0.0918 | 0.0667 | 0.0000 | 0.0000 | 0.0065 | 0.0647 | 0.0971 | 0.1100 | 0.1197 | 0.1553 | 0.4466 | 4 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 10 | 0.0239 | 6.69 | 4.216 | 0.3943 | 52.0 | 441.077 | 4128.92 | 42300.9 | 0.5603 | 0.1272 | 0.0098 | 0.0035 | 0.0446 | 0.0081 | 0.1223 | 0.0190 | 0.1982 | 0.0432 | 0.2580 | 0.0876 | 0.1839 | 0.1643 | 0.1205 | 0.2190 | 0.0509 | 0.2824 | 0.0116 | 0.1729 | 0.0044 | 0.0000 | 0.0196 | 0.0010 | 0.0418 | 0.0068 | 0.0982 | 0.0209 | 0.1483 | 0.0507 | 0.1781 | 0.0989 | 0.1749 | 0.1495 | 0.1477 | 0.2567 | 0.1869 | 0.4155 | 0.1638 | 0.1855 | 0.1048 | 0.0943 | 0.1114 | 0.1006 | 0.1048 | 0.1132 | 0.1201 | 0.1226 | 0.1004 | 0.1164 | 0.1048 | 0.1069 | 0.0873 | 0.0943 | 0.1026 | 0.0660 | 0.0254 | 0.0806 | 0.1569 | 0.1490 | 0.1350 | 0.1060 | 0.1060 | 0.0947 | 0.1464 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 617 | 741 | | 9928 | 9082 | 316.0 | 86.06 | 173.78 | 141.29 | 208 | 240 | 266 | 289 | 311 | 334 | 358 | 388 | 431 | 0.1070 | 972 | 1.101 | 126.49 | 42.11 | 1 | 0.0306 | 304 | 0.0003 | 132.65 | 8.162 | 0.1061 | 107236.0 | 38800000 | 14800000000 | 5960000000000 | 0.4826 | 0.1778 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0107 | 0.0001 | 0.0379 | 0.0016 | 0.1130 | 0.0261 | 0.1926 | 0.0663 | 0.1636 | 0.0767 | 0.1676 | 0.1002 | 0.3147 | 0.7290 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0065 | 0.0006 | 0.0383 | 0.0157 | 0.0809 | 0.0357 | 0.0693 | 0.0321 | 0.0909 | 0.0473 | 0.7140 | 0.8686 | 0.0031 | 0.0012 | 0.0040 | 0.0112 | 0.0058 | 0.0423 | 0.0590 | 0.1270 | 0.1709 | 0.2067 | 0.1789 | 0.1806 | 0.1079 | 0.1071 | 0.1514 | 0.1345 | 0.3191 | 0.1893 | 0.0000 | 0.0013 | 0.0023 | 0.0190 | 0.0877 | 0.1367 | 0.1063 | 0.1354 | 0.5113 | 20 | 36 | 65 | 103 | 143 | 189 | 238 | 298 | 377 | 0.0070 | 34.03 | 6.359 | 0.3017 | 50160.7 | 18200000 | 7670000000 | 3630000000000 | 0.5655 | 0.1272 | 0.0383 | 0.0004 | 0.1678 | 0.0090 | 0.2690 | 0.0860 | 0.1670 | 0.1530 | 0.1338 | 0.1699 | 0.1077 | 0.2023 | 0.0600 | 0.1264 | 0.0304 | 0.1210 | 0.0260 | 0.1321 | 0.0002 | 0.0000 | 0.0002 | 0.0002 | 0.0032 | 0.0011 | 0.0134 | 0.0098 | 0.0646 | 0.0510 | 0.1245 | 0.0968 | 0.0862 | 0.0748 | 0.1433 | 0.1256 | 0.5643 | 0.6408 | 0.0015 | 0.0008 | 0.0012 | 0.0011 | 0.0071 | 0.0072 | 0.0253 | 0.0459 | 0.1085 | 0.1206 | 0.1520 | 0.1714 | 0.1027 | 0.1251 | 0.1640 | 0.1524 | 0.4377 | 0.3754 | 0.0003 | 0.0003 | 0.0053 | 0.0204 | 0.0876 | 0.1385 | 0.1010 | 0.1491 | 0.4976 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 911 | 863 | | 3384 | 11761 | 420.9 | 86.47 | 4.73 | 2.08 | 302 | 339 | 369 | 396 | 423 | 445 | 469 | 496 | 541 | 0.0709 | 834 | 1.119 | 147.57 | 40.85 | 2 | 0.0999 | 338 | 0.0022 | 9.37 | 6.372 | 0.3153 | 184655.0 | 84100000 | 39600000000 | 19200000000000 | 0.4075 | 0.2262 | 0.0000 | 0.0000 | 0.0009 | 0.0003 | 0.0028 | 0.0009 | 0.0122 | 0.0018 | 0.0380 | 0.0163 | 0.0576 | 0.0317 | 0.0595 | 0.0211 | 0.0792 | 0.0350 | 0.7498 | 0.8928 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0044 | 0.0012 | 0.0176 | 0.0145 | 0.0223 | 0.0252 | 0.0223 | 0.0145 | 0.0318 | 0.0228 | 0.9012 | 0.9217 | 0.0017 | 0.0164 | 0.0067 | 0.0820 | 0.0151 | 0.1148 | 0.0334 | 0.0656 | 0.0552 | 0.1475 | 0.0970 | 0.1967 | 0.0719 | 0.0984 | 0.1070 | 0.1148 | 0.6120 | 0.1639 | 0.0006 | 0.0006 | 0.0041 | 0.0122 | 0.0232 | 0.0313 | 0.0481 | 0.0614 | 0.8188 | 3 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 8 | 0.1884 | 0.49 | 1.040 | 0.5055 | 26.7 | 168.516 | 1167.32 | 8724.82 | 0.5573 | 0.1272 | 0.0310 | 0.0008 | 0.1092 | 0.0058 | 0.1823 | 0.0231 | 0.2315 | 0.0675 | 0.2131 | 0.1372 | 0.1494 | 0.2192 | 0.0658 | 0.2642 | 0.0165 | 0.2065 | 0.0011 | 0.0758 | 0.0004 | 0.0000 | 0.0062 | 0.0001 | 0.0262 | 0.0023 | 0.0677 | 0.0103 | 0.1256 | 0.0273 | 0.1932 | 0.0570 | 0.2350 | 0.1221 | 0.2198 | 0.2928 | 0.1259 | 0.4881 | 0.0687 | 0.1947 | 0.1761 | 0.2643 | 0.2285 | 0.2297 | 0.2191 | 0.1457 | 0.1708 | 0.0988 | 0.0955 | 0.0490 | 0.0325 | 0.0152 | 0.0079 | 0.0021 | 0.0008 | 0.0004 | 0.0121 | 0.0572 | 0.1283 | 0.1756 | 0.2122 | 0.1867 | 0.1313 | 0.0730 | 0.0235 | ||
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1060 | 148 | | 9173 | 22344 | 294.9 | 54.87 | 142.27 | 167.42 | 227 | 246 | 262 | 276 | 290 | 304 | 321 | 343 | 371 | 0.0689 | 1540 | 0.872 | 128.71 | 44.38 | 1 | 0.0395 | 362 | 0.0007 | 53.70 | 7.461 | 0.1589 | 89976.7 | 28400000 | 9240000000 | 3100000000000 | 0.4189 | 0.2273 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0039 | 0.0000 | 0.0119 | 0.0010 | 0.0544 | 0.0105 | 0.1011 | 0.0239 | 0.1296 | 0.0218 | 0.1648 | 0.0345 | 0.5330 | 0.9084 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0059 | 0.0002 | 0.0246 | 0.0088 | 0.0420 | 0.0180 | 0.0587 | 0.0104 | 0.0811 | 0.0154 | 0.7860 | 0.9472 | 0.0035 | 0.0359 | 0.0110 | 0.0256 | 0.0311 | 0.0769 | 0.0876 | 0.1487 | 0.1090 | 0.1436 | 0.1739 | 0.1641 | 0.1256 | 0.1128 | 0.1387 | 0.1231 | 0.3195 | 0.1692 | 0.0012 | 0.0047 | 0.0077 | 0.0323 | 0.0798 | 0.1131 | 0.0949 | 0.1254 | 0.5411 | 14 | 17 | 22 | 39 | 72 | 114 | 176 | 260 | 379 | 0.0282 | 29.29 | 5.688 | 0.4480 | 48267.7 | 23800000 | 15100000000 | 12000000000000 | 0.5526 | 0.1273 | 0.0495 | 0.0023 | 0.1676 | 0.0182 | 0.2382 | 0.0872 | 0.1820 | 0.1262 | 0.1201 | 0.1819 | 0.1042 | 0.1777 | 0.0735 | 0.1315 | 0.0360 | 0.1131 | 0.0288 | 0.1618 | 0.0010 | 0.0004 | 0.0013 | 0.0008 | 0.0025 | 0.0027 | 0.0122 | 0.0114 | 0.0574 | 0.0459 | 0.1001 | 0.0810 | 0.0689 | 0.0643 | 0.0971 | 0.0872 | 0.6595 | 0.7063 | 0.0003 | 0.0003 | 0.0007 | 0.0013 | 0.0044 | 0.0053 | 0.0173 | 0.0217 | 0.0820 | 0.0881 | 0.1194 | 0.1360 | 0.0834 | 0.0891 | 0.1164 | 0.1154 | 0.5761 | 0.5428 | 0.0005 | 0.0013 | 0.0029 | 0.0153 | 0.0705 | 0.1085 | 0.0767 | 0.1091 | 0.6152 |