High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 709 | 307 | | 13145 | 33263 | 215.6 | 52.79 | 151.28 | 220.31 | 149 | 174 | 189 | 203 | 216 | 228 | 242 | 259 | 283 | 0.0407 | 1355 | 1.265 | 23.41 | 8.25 | 1 | 0.0043 | 57 | 0.0010 | 34.06 | 7.246 | 0.2053 | 49257.3 | 11800000 | 2960000000 | 769000000000 | 0.3831 | 0.2579 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0040 | 0.0005 | 0.0168 | 0.0025 | 0.0464 | 0.0130 | 0.0932 | 0.0319 | 0.1084 | 0.0316 | 0.1447 | 0.0480 | 0.5842 | 0.8725 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0014 | 0.0001 | 0.0053 | 0.0012 | 0.0169 | 0.0077 | 0.0331 | 0.0189 | 0.0378 | 0.0116 | 0.0514 | 0.0186 | 0.8537 | 0.9419 | 0.0054 | 0.0148 | 0.0050 | 0.0411 | 0.0204 | 0.0542 | 0.0549 | 0.1117 | 0.0976 | 0.1215 | 0.1187 | 0.1560 | 0.1145 | 0.1034 | 0.1287 | 0.1051 | 0.4549 | 0.2923 | 0.0014 | 0.0017 | 0.0065 | 0.0214 | 0.0510 | 0.0797 | 0.0892 | 0.1055 | 0.6436 | 12 | 15 | 20 | 31 | 50 | 92 | 148 | 246 | 442 | 0.0346 | 37.24 | 5.501 | 0.4820 | 71418.1 | 52500000 | 49100000000 | 54400000000000 | 0.4267 | 0.2463 | 0.0312 | 0.0012 | 0.1250 | 0.0165 | 0.2039 | 0.0728 | 0.1419 | 0.0958 | 0.1495 | 0.1578 | 0.1419 | 0.1887 | 0.0914 | 0.1192 | 0.0623 | 0.1242 | 0.0530 | 0.2238 | 0.0005 | 0.0003 | 0.0020 | 0.0009 | 0.0057 | 0.0031 | 0.0160 | 0.0110 | 0.0513 | 0.0476 | 0.0861 | 0.0794 | 0.0620 | 0.0504 | 0.0781 | 0.0712 | 0.6982 | 0.7362 | 0.0005 | 0.0004 | 0.0014 | 0.0037 | 0.0064 | 0.0063 | 0.0183 | 0.0174 | 0.0625 | 0.0699 | 0.1084 | 0.1182 | 0.0749 | 0.0836 | 0.1034 | 0.1020 | 0.6243 | 0.5984 | 0.0008 | 0.0015 | 0.0050 | 0.0158 | 0.0576 | 0.0968 | 0.0701 | 0.0894 | 0.6629 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 592 | 447 | | 14268 | 31171 | 276.5 | 63.92 | 156.47 | 200.54 | 198 | 221 | 239 | 256 | 272 | 288 | 306 | 329 | 363 | 0.0479 | 1493 | 1.112 | 122.50 | 42.44 | 2 | 0.0226 | 322 | 0.0005 | 82.25 | 7.811 | 0.1476 | 80557.2 | 24600000 | 7880000000 | 2630000000000 | 0.4955 | 0.1599 | 0.0002 | 0.0001 | 0.0005 | 0.0001 | 0.0060 | 0.0004 | 0.0222 | 0.0013 | 0.0747 | 0.0210 | 0.1425 | 0.0397 | 0.1357 | 0.0415 | 0.1626 | 0.0645 | 0.4556 | 0.8315 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0051 | 0.0007 | 0.0308 | 0.0126 | 0.0628 | 0.0213 | 0.0597 | 0.0187 | 0.0832 | 0.0292 | 0.7574 | 0.9174 | 0.0026 | 0.0113 | 0.0079 | 0.0213 | 0.0229 | 0.0464 | 0.0649 | 0.1004 | 0.1302 | 0.1757 | 0.1868 | 0.2045 | 0.1028 | 0.1142 | 0.1388 | 0.1380 | 0.3432 | 0.1882 | 0.0004 | 0.0016 | 0.0070 | 0.0240 | 0.0851 | 0.1323 | 0.0987 | 0.1321 | 0.5187 | 11 | 14 | 18 | 26 | 57 | 113 | 187 | 292 | 453 | 0.0385 | 36.22 | 5.629 | 0.4704 | 64696.1 | 37000000 | 25200000000 | 19300000000000 | 0.4742 | 0.1836 | 0.0255 | 0.0014 | 0.1594 | 0.0110 | 0.2636 | 0.0618 | 0.1760 | 0.1240 | 0.1590 | 0.2011 | 0.1042 | 0.2139 | 0.0552 | 0.1298 | 0.0320 | 0.1236 | 0.0251 | 0.1333 | 0.0001 | 0.0001 | 0.0011 | 0.0007 | 0.0017 | 0.0016 | 0.0083 | 0.0060 | 0.0509 | 0.0418 | 0.0820 | 0.0672 | 0.0623 | 0.0538 | 0.0920 | 0.0797 | 0.7017 | 0.7491 | 0.0003 | 0.0008 | 0.0022 | 0.0016 | 0.0045 | 0.0054 | 0.0174 | 0.0185 | 0.0624 | 0.0667 | 0.0988 | 0.1125 | 0.0795 | 0.0787 | 0.1028 | 0.1074 | 0.6320 | 0.6083 | 0.0001 | 0.0006 | 0.0031 | 0.0120 | 0.0572 | 0.0936 | 0.0702 | 0.0963 | 0.6669 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 995 | 506 | | 7348 | 13304 | 328.1 | 66.27 | 48.85 | 74.47 | 255 | 274 | 288 | 301 | 315 | 331 | 351 | 380 | 424 | 0.0735 | 978 | 1.205 | 109.42 | 42.19 | 1 | 0.0378 | 278 | 0.0012 | 31.53 | 7.021 | 0.2102 | 112039.0 | 39900000 | 14800000000 | 5730000000000 | 0.4011 | 0.2457 | 0.0002 | 0.0001 | 0.0018 | 0.0000 | 0.0031 | 0.0004 | 0.0125 | 0.0010 | 0.0478 | 0.0179 | 0.0907 | 0.0300 | 0.1047 | 0.0257 | 0.1396 | 0.0390 | 0.5996 | 0.8857 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0000 | 0.0049 | 0.0004 | 0.0251 | 0.0127 | 0.0451 | 0.0174 | 0.0530 | 0.0121 | 0.0729 | 0.0176 | 0.7965 | 0.9398 | 0.0025 | 0.0027 | 0.0075 | 0.0107 | 0.0207 | 0.0160 | 0.0456 | 0.0587 | 0.0994 | 0.1440 | 0.1135 | 0.1627 | 0.0911 | 0.1253 | 0.1284 | 0.1733 | 0.4913 | 0.3067 | 0.0010 | 0.0036 | 0.0095 | 0.0381 | 0.0733 | 0.1167 | 0.0877 | 0.1023 | 0.5678 | 5 | 6 | 8 | 10 | 15 | 25 | 44 | 78 | 142 | 0.0775 | 3.22 | 3.468 | 0.5712 | 7931.8 | 2060000 | 684000000 | 264000000000 | 0.5693 | 0.1073 | 0.0459 | 0.0072 | 0.1741 | 0.0189 | 0.2799 | 0.0762 | 0.1677 | 0.1610 | 0.1496 | 0.2239 | 0.0823 | 0.1774 | 0.0545 | 0.1385 | 0.0406 | 0.1048 | 0.0053 | 0.0920 | 0.0000 | 0.0012 | 0.0024 | 0.0006 | 0.0019 | 0.0035 | 0.0167 | 0.0141 | 0.0618 | 0.0575 | 0.0992 | 0.0834 | 0.0703 | 0.0653 | 0.1081 | 0.1073 | 0.6396 | 0.6672 | 0.0015 | 0.0003 | 0.0012 | 0.0037 | 0.0042 | 0.0058 | 0.0184 | 0.0299 | 0.0802 | 0.0807 | 0.1100 | 0.1028 | 0.0699 | 0.0879 | 0.1115 | 0.1153 | 0.6031 | 0.5736 | 0.0003 | 0.0008 | 0.0043 | 0.0184 | 0.0714 | 0.1044 | 0.0703 | 0.1164 | 0.6138 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 547 | 289 | | 11285 | 27072 | 244.5 | 58.73 | 197.38 | 232.26 | 172 | 193 | 209 | 224 | 239 | 255 | 274 | 296 | 325 | 0.0436 | 1181 | 1.186 | 113.74 | 45.89 | 1 | 0.0262 | 296 | 0.0006 | 59.04 | 7.598 | 0.1608 | 63242.6 | 17200000 | 4920000000 | 1470000000000 | 0.4595 | 0.1977 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0003 | 0.0222 | 0.0030 | 0.0838 | 0.0183 | 0.1665 | 0.0428 | 0.1519 | 0.0447 | 0.1695 | 0.0687 | 0.4015 | 0.8221 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0009 | 0.0000 | 0.0056 | 0.0015 | 0.0329 | 0.0117 | 0.0689 | 0.0232 | 0.0624 | 0.0202 | 0.0836 | 0.0302 | 0.7454 | 0.9132 | 0.0042 | 0.0118 | 0.0042 | 0.0251 | 0.0161 | 0.0340 | 0.0589 | 0.0991 | 0.1158 | 0.1731 | 0.1866 | 0.1864 | 0.1001 | 0.1080 | 0.1387 | 0.1391 | 0.3753 | 0.2234 | 0.0010 | 0.0019 | 0.0079 | 0.0250 | 0.0784 | 0.1238 | 0.0992 | 0.1291 | 0.5338 | 14 | 18 | 26 | 48 | 94 | 162 | 255 | 375 | 541 | 0.0240 | 59.33 | 6.100 | 0.4045 | 92900.8 | 59800000 | 46700000000 | 42500000000000 | 0.3821 | 0.2440 | 0.0415 | 0.0013 | 0.1747 | 0.0119 | 0.3178 | 0.1184 | 0.1407 | 0.1403 | 0.1199 | 0.1896 | 0.0884 | 0.1946 | 0.0465 | 0.1232 | 0.0336 | 0.1013 | 0.0369 | 0.1196 | 0.0001 | 0.0002 | 0.0000 | 0.0003 | 0.0009 | 0.0010 | 0.0080 | 0.0057 | 0.0480 | 0.0394 | 0.0973 | 0.0776 | 0.0603 | 0.0509 | 0.0905 | 0.0756 | 0.6949 | 0.7492 | 0.0002 | 0.0004 | 0.0020 | 0.0014 | 0.0027 | 0.0026 | 0.0159 | 0.0171 | 0.0664 | 0.0775 | 0.1207 | 0.1335 | 0.0813 | 0.0857 | 0.1106 | 0.1232 | 0.6001 | 0.5585 | 0.0001 | 0.0006 | 0.0019 | 0.0122 | 0.0586 | 0.1142 | 0.0705 | 0.1007 | 0.6412 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 154 | 616 | | 4931 | 13584 | 338.0 | 75.06 | 151.28 | 225.61 | 248 | 276 | 297 | 314 | 331 | 349 | 369 | 393 | 435 | 0.0692 | 940 | 1.116 | 97.91 | 41.00 | 1 | 0.0548 | 270 | 0.0006 | 91.32 | 7.643 | 0.1256 | 119887.0 | 44600000 | 17400000000 | 7130000000000 | 0.4061 | 0.2399 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0049 | 0.0002 | 0.0161 | 0.0013 | 0.0686 | 0.0206 | 0.1481 | 0.0465 | 0.1372 | 0.0463 | 0.1734 | 0.0725 | 0.4504 | 0.8126 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0017 | 0.0000 | 0.0077 | 0.0006 | 0.0334 | 0.0152 | 0.0762 | 0.0307 | 0.0589 | 0.0239 | 0.0885 | 0.0392 | 0.7329 | 0.8904 | 0.0049 | 0.0081 | 0.0173 | 0.0242 | 0.0260 | 0.0524 | 0.0803 | 0.0968 | 0.1224 | 0.1694 | 0.1706 | 0.1653 | 0.0952 | 0.1250 | 0.1323 | 0.1169 | 0.3511 | 0.2419 | 0.0026 | 0.0062 | 0.0132 | 0.0352 | 0.0835 | 0.1266 | 0.0976 | 0.1196 | 0.5156 | 12 | 15 | 17 | 21 | 30 | 64 | 148 | 279 | 478 | 0.0547 | 37.91 | 5.028 | 0.5176 | 73778.3 | 50900000 | 41900000000 | 39000000000000 | 0.5433 | 0.1208 | 0.1000 | 0.0025 | 0.2590 | 0.0318 | 0.2667 | 0.2116 | 0.1359 | 0.1906 | 0.0692 | 0.1957 | 0.0628 | 0.1449 | 0.0590 | 0.0870 | 0.0308 | 0.0654 | 0.0167 | 0.0705 | 0.0005 | 0.0000 | 0.0002 | 0.0004 | 0.0014 | 0.0018 | 0.0110 | 0.0108 | 0.0529 | 0.0494 | 0.0964 | 0.0818 | 0.0669 | 0.0566 | 0.1009 | 0.0895 | 0.6698 | 0.7097 | 0.0003 | 0.0003 | 0.0008 | 0.0009 | 0.0019 | 0.0021 | 0.0109 | 0.0162 | 0.0702 | 0.0748 | 0.1117 | 0.1200 | 0.0803 | 0.0967 | 0.1268 | 0.1281 | 0.5970 | 0.5609 | 0.0000 | 0.0025 | 0.0025 | 0.0099 | 0.0656 | 0.0992 | 0.0705 | 0.1173 | 0.6325 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 972 | 297 | | 4771 | 7211 | 303.5 | 65.31 | 240.93 | 226.65 | 218 | 246 | 266 | 285 | 301 | 318 | 336 | 359 | 393 | 0.1144 | 825 | 0.746 | 99.85 | 18.25 | 1 | 0.0470 | 224 | 0.0006 | 79.54 | 7.546 | 0.1380 | 96372.4 | 31900000 | 11000000000 | 3900000000000 | 0.4166 | 0.2336 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0180 | 0.0018 | 0.0709 | 0.0195 | 0.1275 | 0.0424 | 0.1468 | 0.0462 | 0.1774 | 0.0735 | 0.4551 | 0.8167 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0004 | 0.0315 | 0.0150 | 0.0601 | 0.0295 | 0.0668 | 0.0242 | 0.0840 | 0.0406 | 0.7492 | 0.8903 | 0.0069 | 0.0237 | 0.0183 | 0.0473 | 0.0171 | 0.1065 | 0.0674 | 0.1598 | 0.1063 | 0.2189 | 0.1337 | 0.1479 | 0.1029 | 0.0651 | 0.1349 | 0.0947 | 0.4126 | 0.1361 | 0.0004 | 0.0004 | 0.0056 | 0.0299 | 0.0837 | 0.1205 | 0.1008 | 0.1166 | 0.5421 | 18 | 24 | 51 | 105 | 176 | 253 | 344 | 445 | 581 | 0.0200 | 42.53 | 6.319 | 0.3498 | 109411.0 | 62100000 | 40100000000 | 28400000000000 | 0.5244 | 0.1362 | 0.0141 | 0.0041 | 0.1315 | 0.0113 | 0.1984 | 0.0504 | 0.1737 | 0.0989 | 0.2007 | 0.1819 | 0.1080 | 0.2044 | 0.0869 | 0.1380 | 0.0552 | 0.1220 | 0.0317 | 0.1890 | 0.0003 | 0.0000 | 0.0020 | 0.0008 | 0.0014 | 0.0013 | 0.0098 | 0.0072 | 0.0571 | 0.0424 | 0.0704 | 0.0721 | 0.0637 | 0.0570 | 0.0947 | 0.0816 | 0.7006 | 0.7377 | 0.0004 | 0.0005 | 0.0023 | 0.0027 | 0.0104 | 0.0068 | 0.0154 | 0.0263 | 0.0677 | 0.0693 | 0.0903 | 0.1014 | 0.0765 | 0.0928 | 0.1107 | 0.1241 | 0.6263 | 0.5761 | 0.0003 | 0.0027 | 0.0020 | 0.0140 | 0.0578 | 0.0905 | 0.0708 | 0.1002 | 0.6617 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 477 | 250 | | 5842 | 6724 | 472.6 | 109.57 | 64.97 | 82.36 | 352 | 384 | 409 | 431 | 454 | 480 | 513 | 551 | 621 | 0.1120 | 753 | 1.059 | 127.44 | 46.01 | 1 | 0.0580 | 339 | 0.0010 | 46.76 | 7.191 | 0.1916 | 235384.0 | 124000000 | 68700000000 | 40200000000000 | 0.4185 | 0.2273 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0051 | 0.0000 | 0.0183 | 0.0015 | 0.0595 | 0.0197 | 0.1231 | 0.0436 | 0.1215 | 0.0347 | 0.1414 | 0.0528 | 0.5311 | 0.8478 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0061 | 0.0000 | 0.0303 | 0.0139 | 0.0654 | 0.0255 | 0.0629 | 0.0177 | 0.0794 | 0.0279 | 0.7550 | 0.9150 | 0.0020 | 0.0082 | 0.0049 | 0.0109 | 0.0225 | 0.0136 | 0.0470 | 0.0625 | 0.1136 | 0.1223 | 0.1185 | 0.1929 | 0.0803 | 0.0870 | 0.1156 | 0.1304 | 0.4956 | 0.3723 | 0.0012 | 0.0040 | 0.0064 | 0.0302 | 0.0770 | 0.1132 | 0.0870 | 0.1140 | 0.5671 | 5 | 7 | 9 | 13 | 27 | 45 | 76 | 118 | 187 | 0.0898 | 5.57 | 4.185 | 0.6123 | 11003.2 | 2590000 | 720000000 | 223000000000 | 0.5988 | 0.0846 | 0.0147 | 0.0063 | 0.0939 | 0.0135 | 0.2413 | 0.0387 | 0.1971 | 0.0729 | 0.1823 | 0.1674 | 0.1050 | 0.2115 | 0.0958 | 0.1476 | 0.0405 | 0.1611 | 0.0295 | 0.1809 | 0.0004 | 0.0025 | 0.0000 | 0.0011 | 0.0016 | 0.0035 | 0.0130 | 0.0074 | 0.0438 | 0.0337 | 0.0686 | 0.0561 | 0.0603 | 0.0459 | 0.0832 | 0.0775 | 0.7292 | 0.7724 | 0.0000 | 0.0000 | 0.0015 | 0.0046 | 0.0040 | 0.0040 | 0.0206 | 0.0259 | 0.0667 | 0.0856 | 0.1003 | 0.1086 | 0.0832 | 0.0851 | 0.1169 | 0.1132 | 0.6068 | 0.5730 | 0.0000 | 0.0000 | 0.0044 | 0.0146 | 0.0521 | 0.0838 | 0.0710 | 0.1094 | 0.6648 | ||
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1109 | 467 | | 7728 | 10985 | 187.4 | 61.96 | 106.16 | 170.18 | 109 | 128 | 147 | 169 | 186 | 203 | 220 | 239 | 268 | 0.0861 | 946 | 1.180 | 100.90 | 29.02 | 3 | 0.0294 | 227 | 0.0011 | 27.43 | 7.104 | 0.2644 | 38959.5 | 8810000 | 2140000000 | 549000000000 | 0.4404 | 0.1893 | 0.0019 | 0.0005 | 0.0066 | 0.0013 | 0.0109 | 0.0023 | 0.0241 | 0.0084 | 0.0675 | 0.0240 | 0.0947 | 0.0473 | 0.0944 | 0.0455 | 0.1310 | 0.0624 | 0.5688 | 0.8083 | 0.0006 | 0.0003 | 0.0015 | 0.0009 | 0.0032 | 0.0012 | 0.0043 | 0.0039 | 0.0171 | 0.0115 | 0.0221 | 0.0195 | 0.0225 | 0.0169 | 0.0332 | 0.0232 | 0.8955 | 0.9226 | 0.0028 | 0.0045 | 0.0052 | 0.0034 | 0.0131 | 0.0101 | 0.0197 | 0.0515 | 0.0553 | 0.1074 | 0.0933 | 0.1398 | 0.0778 | 0.1040 | 0.1172 | 0.1275 | 0.6157 | 0.4519 | 0.0003 | 0.0005 | 0.0034 | 0.0120 | 0.0330 | 0.0494 | 0.0546 | 0.0738 | 0.7730 | 10 | 13 | 16 | 20 | 29 | 52 | 97 | 156 | 295 | 0.0735 | 19.46 | 4.540 | 0.5815 | 40229.5 | 25000000 | 19500000000 | 17300000000000 | 0.4726 | 0.1847 | 0.0486 | 0.0029 | 0.0972 | 0.0161 | 0.1627 | 0.0732 | 0.1333 | 0.0992 | 0.1345 | 0.1522 | 0.1390 | 0.1690 | 0.0949 | 0.1107 | 0.0836 | 0.1148 | 0.1062 | 0.2618 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0042 | 0.0027 | 0.0152 | 0.0126 | 0.0576 | 0.0567 | 0.0829 | 0.0680 | 0.0576 | 0.0508 | 0.0880 | 0.0841 | 0.6936 | 0.7242 | 0.0007 | 0.0009 | 0.0045 | 0.0047 | 0.0064 | 0.0108 | 0.0288 | 0.0284 | 0.0804 | 0.0814 | 0.0932 | 0.1063 | 0.0718 | 0.0689 | 0.1044 | 0.1029 | 0.6098 | 0.5958 | 0.0003 | 0.0019 | 0.0055 | 0.0183 | 0.0685 | 0.0985 | 0.0711 | 0.1046 | 0.6313 | ||
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 702 | 223 | | 941 | 12390 | 79.6 | 29.54 | 182.48 | 238.48 | 36 | 53 | 62 | 72 | 81 | 87 | 96 | 106 | 120 | 0.0553 | 685 | 0.420 | 238.65 | 45.22 | 1 | 0.8013 | 754 | 0.0030 | 21.04 | 6.013 | 0.2638 | 7208.4 | 713221 | 75200000 | 8310000000 | 0.4207 | 0.1971 | 0.0028 | 0.0000 | 0.0140 | 0.0000 | 0.0955 | 0.0016 | 0.1124 | 0.0078 | 0.1376 | 0.0889 | 0.1713 | 0.1404 | 0.1292 | 0.1420 | 0.1573 | 0.1451 | 0.1798 | 0.4743 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0077 | 0.0025 | 0.0526 | 0.0406 | 0.0896 | 0.0570 | 0.0526 | 0.0456 | 0.0881 | 0.0646 | 0.7079 | 0.7896 | 0.0000 | 0.0068 | 0.0069 | 0.0000 | 0.0309 | 0.0270 | 0.0378 | 0.1216 | 0.1478 | 0.2027 | 0.1890 | 0.2027 | 0.1168 | 0.1757 | 0.1787 | 0.1622 | 0.2921 | 0.1014 | 0.0000 | 0.0020 | 0.0041 | 0.0244 | 0.0815 | 0.1120 | 0.1303 | 0.1589 | 0.4868 | 13 | 16 | 20 | 30 | 62 | 129 | 225 | 349 | 522 | 0.0743 | 27.27 | 5.116 | 0.5188 | 90166.0 | 64100000 | 58300000000 | 64100000000000 | 0.4933 | 0.1833 | 0.0624 | 0.0027 | 0.1895 | 0.0226 | 0.2793 | 0.1183 | 0.1763 | 0.1656 | 0.1490 | 0.2005 | 0.0876 | 0.1919 | 0.0394 | 0.1156 | 0.0153 | 0.1102 | 0.0011 | 0.0726 | 0.0004 | 0.0002 | 0.0023 | 0.0013 | 0.0047 | 0.0036 | 0.0157 | 0.0126 | 0.0591 | 0.0491 | 0.0882 | 0.0803 | 0.0608 | 0.0573 | 0.0914 | 0.0794 | 0.6774 | 0.7162 | 0.0005 | 0.0015 | 0.0024 | 0.0015 | 0.0061 | 0.0041 | 0.0198 | 0.0215 | 0.0614 | 0.0684 | 0.1002 | 0.1256 | 0.0833 | 0.0902 | 0.1091 | 0.1368 | 0.6172 | 0.5505 | 0.0019 | 0.0029 | 0.0038 | 0.0150 | 0.0588 | 0.0954 | 0.0711 | 0.1004 | 0.6507 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 164 | 879 | | 4050 | 8872 | 419.4 | 110.73 | 86.10 | 234.18 | 295 | 334 | 362 | 385 | 409 | 439 | 474 | 515 | 570 | 0.0979 | 869 | 0.960 | 155.00 | 54.01 | 3 | 0.1049 | 425 | 0.0007 | 76.29 | 7.489 | 0.1602 | 188142.0 | 89200000 | 44400000000 | 23100000000000 | 0.4137 | 0.2255 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0052 | 0.0000 | 0.0231 | 0.0043 | 0.0718 | 0.0210 | 0.1144 | 0.0459 | 0.1271 | 0.0397 | 0.1462 | 0.0559 | 0.5100 | 0.8333 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0000 | 0.0071 | 0.0013 | 0.0298 | 0.0149 | 0.0481 | 0.0238 | 0.0528 | 0.0149 | 0.0708 | 0.0245 | 0.7886 | 0.9206 | 0.0011 | 0.0000 | 0.0043 | 0.0099 | 0.0130 | 0.0099 | 0.0444 | 0.0759 | 0.0704 | 0.1452 | 0.1083 | 0.1716 | 0.0986 | 0.1089 | 0.1073 | 0.1584 | 0.5525 | 0.3201 | 0.0016 | 0.0032 | 0.0111 | 0.0185 | 0.0506 | 0.0749 | 0.0611 | 0.0870 | 0.6921 | 11 | 12 | 14 | 15 | 16 | 17 | 20 | 35 | 226 | 0.4982 | 14.49 | 2.220 | 0.8059 | 62249.3 | 81200000 | 135000000000 | 258000000000000 | 0.6303 | 0.0763 | 0.2131 | 0.0132 | 0.4262 | 0.1376 | 0.2295 | 0.3995 | 0.0546 | 0.1508 | 0.0546 | 0.1164 | 0.0219 | 0.1085 | 0.0000 | 0.0423 | 0.0000 | 0.0265 | 0.0000 | 0.0053 | 0.0007 | 0.0006 | 0.0055 | 0.0019 | 0.0097 | 0.0070 | 0.0194 | 0.0171 | 0.0947 | 0.0912 | 0.1418 | 0.1476 | 0.0705 | 0.0646 | 0.0961 | 0.0956 | 0.5615 | 0.5744 | 0.0008 | 0.0008 | 0.0032 | 0.0042 | 0.0071 | 0.0100 | 0.0301 | 0.0308 | 0.1013 | 0.1032 | 0.1362 | 0.1424 | 0.0831 | 0.0849 | 0.1077 | 0.1091 | 0.5305 | 0.5146 | 0.0022 | 0.0037 | 0.0066 | 0.0176 | 0.1051 | 0.1412 | 0.0713 | 0.1037 | 0.5485 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 509 | 507 | | 7824 | 25276 | 555.9 | 107.56 | 87.69 | 105.95 | 423 | 462 | 493 | 518 | 545 | 575 | 609 | 649 | 706 | 0.0436 | 1102 | 1.007 | 126.85 | 35.51 | 1 | 0.0387 | 303 | 0.0006 | 69.54 | 7.651 | 0.1417 | 320582.0 | 192000000 | 118000000000 | 75400000000000 | 0.3901 | 0.2585 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0078 | 0.0004 | 0.0495 | 0.0148 | 0.1105 | 0.0312 | 0.1156 | 0.0262 | 0.1566 | 0.0356 | 0.5585 | 0.8919 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0027 | 0.0000 | 0.0235 | 0.0112 | 0.0491 | 0.0226 | 0.0541 | 0.0132 | 0.0699 | 0.0177 | 0.7998 | 0.9352 | 0.0031 | 0.0092 | 0.0086 | 0.0323 | 0.0163 | 0.0276 | 0.0467 | 0.1198 | 0.1346 | 0.1935 | 0.1486 | 0.2166 | 0.1121 | 0.1106 | 0.1307 | 0.1290 | 0.3992 | 0.1613 | 0.0008 | 0.0025 | 0.0044 | 0.0227 | 0.0729 | 0.1111 | 0.1003 | 0.1279 | 0.5575 | 8 | 10 | 12 | 19 | 41 | 74 | 111 | 159 | 230 | 0.0557 | 17.43 | 5.062 | 0.4981 | 18913.8 | 5940000 | 2360000000 | 1110000000000 | 0.5214 | 0.1569 | 0.0217 | 0.0010 | 0.1318 | 0.0082 | 0.2484 | 0.0573 | 0.1624 | 0.1006 | 0.1628 | 0.1863 | 0.1092 | 0.2103 | 0.0691 | 0.1325 | 0.0507 | 0.1178 | 0.0438 | 0.1859 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0013 | 0.0003 | 0.0090 | 0.0059 | 0.0434 | 0.0366 | 0.0864 | 0.0707 | 0.0600 | 0.0485 | 0.0853 | 0.0637 | 0.7144 | 0.7741 | 0.0004 | 0.0001 | 0.0010 | 0.0009 | 0.0023 | 0.0038 | 0.0153 | 0.0204 | 0.0611 | 0.0695 | 0.1126 | 0.1258 | 0.0774 | 0.0886 | 0.1029 | 0.1191 | 0.6271 | 0.5718 | 0.0000 | 0.0001 | 0.0020 | 0.0125 | 0.0561 | 0.0967 | 0.0714 | 0.0968 | 0.6644 | ||
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 688 | 724 | | 382 | 3170 | 111.2 | 49.61 | 43.27 | 125.08 | 45 | 55 | 71 | 91 | 111 | 133 | 151 | 163 | 177 | 0.1344 | 426 | 0.422 | 253.34 | 46.17 | 1 | 2.3037 | 880 | 0.0037 | 31.49 | 5.680 | 0.1888 | 14813.4 | 2190000 | 345000000 | 56300000000 | 0.2747 | 0.3491 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.2262 | 0.0345 | 0.3929 | 0.1379 | 0.2857 | 0.2184 | 0.0357 | 0.1494 | 0.0595 | 0.2184 | 0.0000 | 0.2356 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0072 | 0.0681 | 0.0578 | 0.0851 | 0.0866 | 0.0511 | 0.0433 | 0.0681 | 0.0650 | 0.7191 | 0.7401 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0194 | 0.0927 | 0.1553 | 0.1192 | 0.1165 | 0.0397 | 0.0971 | 0.1060 | 0.1165 | 0.6424 | 0.4854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0733 | 0.1257 | 0.0314 | 0.0733 | 0.6963 | 7 | 8 | 9 | 10 | 10 | 11 | 12 | 15 | 33 | 0.6117 | 5.34 | 1.436 | 0.8850 | 17511.8 | 11000000 | 7740000000 | 5940000000000 | 0.6927 | 0.0495 | 0.0357 | 0.0000 | 0.1429 | 0.0385 | 0.2857 | 0.0641 | 0.2143 | 0.1538 | 0.1786 | 0.2436 | 0.1429 | 0.1923 | 0.0000 | 0.1154 | 0.0000 | 0.1538 | 0.0000 | 0.0385 | 0.0032 | 0.0000 | 0.0064 | 0.0085 | 0.0064 | 0.0141 | 0.0129 | 0.0226 | 0.0386 | 0.0621 | 0.0611 | 0.0424 | 0.0675 | 0.0621 | 0.0868 | 0.1017 | 0.7170 | 0.6864 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0035 | 0.0000 | 0.0106 | 0.0181 | 0.0565 | 0.0471 | 0.0636 | 0.0870 | 0.0777 | 0.0725 | 0.0777 | 0.0725 | 0.7102 | 0.6993 | 0.0000 | 0.0000 | 0.0068 | 0.0102 | 0.0476 | 0.0612 | 0.0714 | 0.0884 | 0.7143 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 318 | 872 | | 12186 | 25790 | 350.1 | 84.35 | 180.74 | 231.33 | 250 | 278 | 300 | 319 | 340 | 362 | 386 | 419 | 463 | 0.0459 | 1185 | 1.241 | 90.52 | 37.58 | 1 | 0.0197 | 240 | 0.0006 | 79.84 | 7.705 | 0.1428 | 129698.0 | 50800000 | 21000000000 | 9160000000000 | 0.4637 | 0.1985 | 0.0008 | 0.0000 | 0.0050 | 0.0002 | 0.0093 | 0.0019 | 0.0269 | 0.0039 | 0.0810 | 0.0184 | 0.1487 | 0.0417 | 0.1625 | 0.0489 | 0.1712 | 0.0732 | 0.3947 | 0.8118 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0020 | 0.0001 | 0.0091 | 0.0003 | 0.0330 | 0.0101 | 0.0662 | 0.0219 | 0.0745 | 0.0199 | 0.0941 | 0.0344 | 0.7203 | 0.9133 | 0.0050 | 0.0088 | 0.0083 | 0.0113 | 0.0190 | 0.0479 | 0.0690 | 0.1614 | 0.1467 | 0.1589 | 0.1789 | 0.2320 | 0.1149 | 0.1236 | 0.1471 | 0.1097 | 0.3112 | 0.1463 | 0.0009 | 0.0031 | 0.0086 | 0.0355 | 0.0810 | 0.1311 | 0.1118 | 0.1336 | 0.4943 | 10 | 15 | 25 | 45 | 80 | 130 | 204 | 324 | 514 | 0.0440 | 29.42 | 5.543 | 0.4890 | 86176.2 | 59000000 | 49700000000 | 48200000000000 | 0.4861 | 0.1546 | 0.0520 | 0.0023 | 0.1701 | 0.0129 | 0.2665 | 0.0966 | 0.1459 | 0.1378 | 0.1201 | 0.1935 | 0.1172 | 0.1886 | 0.0605 | 0.1155 | 0.0372 | 0.1007 | 0.0305 | 0.1521 | 0.0003 | 0.0004 | 0.0012 | 0.0006 | 0.0023 | 0.0023 | 0.0133 | 0.0093 | 0.0591 | 0.0486 | 0.0997 | 0.0816 | 0.0694 | 0.0558 | 0.1037 | 0.0915 | 0.6512 | 0.7099 | 0.0005 | 0.0003 | 0.0007 | 0.0026 | 0.0046 | 0.0032 | 0.0156 | 0.0218 | 0.0784 | 0.0855 | 0.1293 | 0.1333 | 0.0752 | 0.0852 | 0.1163 | 0.1277 | 0.5793 | 0.5404 | 0.0006 | 0.0014 | 0.0033 | 0.0161 | 0.0656 | 0.1205 | 0.0715 | 0.1126 | 0.6084 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 818 | 411 | | 1111 | 7364 | 67.7 | 19.08 | 51.50 | 75.73 | 43 | 51 | 58 | 63 | 67 | 72 | 77 | 83 | 92 | 0.0743 | 547 | 0.895 | 205.46 | 68.66 | 1 | 0.5041 | 560 | 0.0025 | 26.29 | 6.146 | 0.2030 | 4951.3 | 386036 | 31800000 | 2760000000 | 0.4919 | 0.1558 | 0.0017 | 0.0000 | 0.0084 | 0.0000 | 0.0506 | 0.0042 | 0.0759 | 0.0116 | 0.1433 | 0.0582 | 0.1855 | 0.0857 | 0.1484 | 0.1228 | 0.2024 | 0.1185 | 0.1838 | 0.5989 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0237 | 0.0078 | 0.0580 | 0.0447 | 0.1018 | 0.0438 | 0.0994 | 0.0720 | 0.1515 | 0.0730 | 0.5657 | 0.7588 | 0.0198 | 0.0241 | 0.0238 | 0.0361 | 0.0437 | 0.1566 | 0.1032 | 0.2289 | 0.1468 | 0.1325 | 0.2103 | 0.1687 | 0.1071 | 0.0602 | 0.1151 | 0.0482 | 0.2302 | 0.1446 | 0.0000 | 0.0036 | 0.0163 | 0.0470 | 0.1501 | 0.1410 | 0.1338 | 0.1591 | 0.3490 | 15 | 17 | 18 | 21 | 24 | 29 | 39 | 59 | 117 | 0.2303 | 3.57 | 2.698 | 0.7805 | 8387.2 | 2780000 | 1260000000 | 683000000000 | 0.4695 | 0.1988 | 0.0338 | 0.0076 | 0.1132 | 0.0146 | 0.2294 | 0.0419 | 0.1779 | 0.1017 | 0.1647 | 0.1773 | 0.1250 | 0.1919 | 0.0632 | 0.1582 | 0.0662 | 0.1264 | 0.0265 | 0.1804 | 0.0057 | 0.0035 | 0.0047 | 0.0053 | 0.0095 | 0.0114 | 0.0218 | 0.0252 | 0.0816 | 0.0650 | 0.1044 | 0.0919 | 0.0745 | 0.0831 | 0.1144 | 0.1136 | 0.5833 | 0.6010 | 0.0007 | 0.0016 | 0.0042 | 0.0032 | 0.0049 | 0.0048 | 0.0329 | 0.0322 | 0.0988 | 0.0893 | 0.1142 | 0.1376 | 0.0883 | 0.0837 | 0.1065 | 0.1255 | 0.5494 | 0.5221 | 0.0029 | 0.0041 | 0.0088 | 0.0269 | 0.0779 | 0.1265 | 0.0715 | 0.1154 | 0.5659 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 632 | 365 | | 4889 | 13256 | 383.0 | 256.14 | 34.30 | 57.66 | 183 | 197 | 211 | 228 | 257 | 316 | 420 | 590 | 842 | 0.0671 | 890 | 0.504 | 95.59 | 26.87 | 10 | 0.0714 | 349 | 0.0027 | 26.56 | 6.768 | 0.3301 | 212277.0 | 153000000 | 126000000000 | 111000000000000 | 0.4295 | 0.1988 | 0.0014 | 0.0022 | 0.0000 | 0.0011 | 0.0177 | 0.0092 | 0.0477 | 0.0152 | 0.1376 | 0.0656 | 0.2030 | 0.1062 | 0.1444 | 0.0846 | 0.1253 | 0.1084 | 0.3229 | 0.6076 | 0.0000 | 0.0014 | 0.0000 | 0.0007 | 0.0010 | 0.0058 | 0.0030 | 0.0093 | 0.0272 | 0.0319 | 0.0495 | 0.0436 | 0.0302 | 0.0367 | 0.0475 | 0.0480 | 0.8417 | 0.8226 | 0.0000 | 0.0019 | 0.0000 | 0.0000 | 0.0039 | 0.0000 | 0.0070 | 0.0056 | 0.0396 | 0.0318 | 0.0591 | 0.0589 | 0.0311 | 0.0308 | 0.0521 | 0.0421 | 0.8073 | 0.8290 | 0.0000 | 0.0000 | 0.0000 | 0.0055 | 0.0325 | 0.0644 | 0.0319 | 0.0576 | 0.8081 | 6 | 7 | 9 | 11 | 13 | 17 | 25 | 40 | 85 | 0.1143 | 7.18 | 3.518 | 0.6992 | 4501.5 | 1130000 | 367000000 | 138000000000 | 0.5010 | 0.1794 | 0.0284 | 0.0102 | 0.0869 | 0.0191 | 0.1446 | 0.0339 | 0.1683 | 0.0750 | 0.1629 | 0.1280 | 0.1299 | 0.1522 | 0.1034 | 0.1314 | 0.1052 | 0.1526 | 0.0704 | 0.2976 | 0.0040 | 0.0039 | 0.0059 | 0.0071 | 0.0075 | 0.0092 | 0.0215 | 0.0184 | 0.0557 | 0.0417 | 0.0796 | 0.0708 | 0.0632 | 0.0565 | 0.0866 | 0.0877 | 0.6759 | 0.7047 | 0.0019 | 0.0022 | 0.0019 | 0.0013 | 0.0095 | 0.0056 | 0.0175 | 0.0233 | 0.0712 | 0.0739 | 0.1086 | 0.1188 | 0.0712 | 0.0774 | 0.1036 | 0.1059 | 0.6145 | 0.5916 | 0.0032 | 0.0064 | 0.0051 | 0.0185 | 0.0543 | 0.1006 | 0.0716 | 0.1016 | 0.6387 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 946 | 255 | | 1237 | 5097 | 597.6 | 154.71 | 26.89 | 29.04 | 397 | 436 | 482 | 531 | 589 | 647 | 701 | 753 | 822 | 0.1214 | 619 | 1.247 | 102.24 | 42.95 | 1 | 0.2183 | 270 | 0.0018 | 17.17 | 6.438 | 0.2538 | 381056.0 | 257000000 | 181000000000 | 133000000000000 | 0.3962 | 0.2297 | 0.0000 | 0.0000 | 0.0037 | 0.0009 | 0.0093 | 0.0018 | 0.0223 | 0.0080 | 0.0801 | 0.0312 | 0.1657 | 0.0714 | 0.1192 | 0.0562 | 0.1546 | 0.0714 | 0.4451 | 0.7591 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0092 | 0.0016 | 0.0264 | 0.0246 | 0.0608 | 0.0493 | 0.0321 | 0.0271 | 0.0585 | 0.0427 | 0.8131 | 0.8539 | 0.0000 | 0.0103 | 0.0000 | 0.0206 | 0.0060 | 0.0412 | 0.0269 | 0.0619 | 0.0716 | 0.1443 | 0.1134 | 0.1753 | 0.0866 | 0.0825 | 0.0925 | 0.1753 | 0.6030 | 0.2887 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0434 | 0.0634 | 0.0467 | 0.0768 | 0.7596 | 6 | 7 | 8 | 10 | 13 | 19 | 28 | 45 | 74 | 0.1481 | 0.93 | 2.851 | 0.7106 | 1566.2 | 129062 | 12400000 | 1310000000 | 0.4006 | 0.2163 | 0.0291 | 0.0139 | 0.1414 | 0.0268 | 0.2557 | 0.0606 | 0.2370 | 0.1480 | 0.1705 | 0.2205 | 0.1019 | 0.1768 | 0.0437 | 0.1609 | 0.0146 | 0.1231 | 0.0062 | 0.0695 | 0.0016 | 0.0054 | 0.0022 | 0.0054 | 0.0141 | 0.0117 | 0.0255 | 0.0252 | 0.0662 | 0.0667 | 0.0950 | 0.0812 | 0.0787 | 0.0744 | 0.0944 | 0.1019 | 0.6224 | 0.6280 | 0.0029 | 0.0025 | 0.0059 | 0.0033 | 0.0095 | 0.0190 | 0.0352 | 0.0355 | 0.0808 | 0.0809 | 0.0932 | 0.0884 | 0.0712 | 0.0710 | 0.0991 | 0.1057 | 0.6021 | 0.5937 | 0.0025 | 0.0056 | 0.0124 | 0.0324 | 0.0678 | 0.1008 | 0.0716 | 0.0965 | 0.6105 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1200 | 960 | | 312 | 3292 | 82.5 | 11.29 | 23.21 | 72.43 | 68 | 73 | 76 | 79 | 82 | 86 | 89 | 93 | 97 | 0.1206 | 397 | 1.136 | 33.29 | 11.66 | 2 | 0.2724 | 85 | 0.0754 | 0.90 | 2.811 | 0.6827 | 6932.2 | 592793 | 51500000 | 4550000000 | 0.3990 | 0.2389 | 0.0037 | 0.0000 | 0.0000 | 0.0032 | 0.0112 | 0.0000 | 0.0485 | 0.0096 | 0.0672 | 0.0737 | 0.1194 | 0.0833 | 0.0933 | 0.0481 | 0.1604 | 0.0705 | 0.4963 | 0.7115 | 0.0034 | 0.0000 | 0.0000 | 0.0032 | 0.0069 | 0.0000 | 0.0206 | 0.0096 | 0.0481 | 0.0737 | 0.0997 | 0.0833 | 0.0378 | 0.0481 | 0.0722 | 0.0705 | 0.7113 | 0.7115 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.2609 | 0.0000 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0120 | 0.0180 | 0.0299 | 0.0539 | 0.0898 | 0.2275 | 0.0958 | 0.1078 | 0.3653 | 5 | 6 | 8 | 8 | 9 | 10 | 11 | 12 | 16 | 0.2788 | 2.99 | 1.539 | 0.6666 | 5783.0 | 2740000 | 1470000000 | 851000000000 | 0.3576 | 0.2571 | 0.1333 | 0.2774 | 0.2167 | 0.1473 | 0.3500 | 0.1130 | 0.1833 | 0.1541 | 0.0833 | 0.1336 | 0.0333 | 0.1199 | 0.0000 | 0.0411 | 0.0000 | 0.0103 | 0.0000 | 0.0034 | 0.0217 | 0.1656 | 0.0072 | 0.0879 | 0.0109 | 0.0573 | 0.0217 | 0.0613 | 0.0435 | 0.0327 | 0.0942 | 0.0675 | 0.0471 | 0.0409 | 0.0870 | 0.0695 | 0.6667 | 0.4172 | 0.0000 | 0.0000 | 0.0093 | 0.0000 | 0.0046 | 0.0000 | 0.0139 | 0.0203 | 0.0509 | 0.0711 | 0.1111 | 0.0863 | 0.0556 | 0.0761 | 0.0787 | 0.0863 | 0.6759 | 0.6599 | 0.0042 | 0.0042 | 0.0211 | 0.0253 | 0.0506 | 0.0717 | 0.0717 | 0.0928 | 0.6582 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 241 | 848 | | 10173 | 33400 | 558.7 | 106.36 | 141.20 | 210.07 | 440 | 469 | 494 | 517 | 539 | 564 | 595 | 638 | 721 | 0.0340 | 1136 | 1.181 | 125.88 | 48.08 | 1 | 0.0321 | 327 | 0.0010 | 33.71 | 7.169 | 0.1994 | 323447.0 | 194000000 | 121000000000 | 78500000000000 | 0.3999 | 0.2475 | 0.0004 | 0.0002 | 0.0009 | 0.0001 | 0.0027 | 0.0002 | 0.0123 | 0.0021 | 0.0344 | 0.0148 | 0.0701 | 0.0282 | 0.0822 | 0.0219 | 0.1201 | 0.0283 | 0.6769 | 0.9042 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0077 | 0.0002 | 0.0193 | 0.0092 | 0.0401 | 0.0151 | 0.0464 | 0.0088 | 0.0651 | 0.0146 | 0.8195 | 0.9521 | 0.0060 | 0.0020 | 0.0079 | 0.0101 | 0.0113 | 0.0061 | 0.0344 | 0.0869 | 0.0656 | 0.1212 | 0.0947 | 0.2222 | 0.0742 | 0.1253 | 0.0947 | 0.1616 | 0.6113 | 0.2646 | 0.0019 | 0.0063 | 0.0137 | 0.0288 | 0.0574 | 0.1020 | 0.0876 | 0.1004 | 0.6019 | 7 | 9 | 12 | 16 | 31 | 71 | 144 | 264 | 446 | 0.0759 | 52.63 | 5.308 | 0.4892 | 64064.9 | 41000000 | 31800000000 | 28400000000000 | 0.3985 | 0.2299 | 0.1332 | 0.0028 | 0.3108 | 0.0481 | 0.2982 | 0.2452 | 0.1039 | 0.2139 | 0.0716 | 0.1845 | 0.0484 | 0.1328 | 0.0222 | 0.0737 | 0.0081 | 0.0576 | 0.0035 | 0.0413 | 0.0002 | 0.0002 | 0.0008 | 0.0002 | 0.0013 | 0.0007 | 0.0107 | 0.0085 | 0.0677 | 0.0583 | 0.1067 | 0.0940 | 0.0684 | 0.0620 | 0.1038 | 0.0989 | 0.6404 | 0.6771 | 0.0001 | 0.0001 | 0.0004 | 0.0005 | 0.0018 | 0.0038 | 0.0161 | 0.0195 | 0.0838 | 0.0907 | 0.1222 | 0.1354 | 0.0813 | 0.0869 | 0.1259 | 0.1305 | 0.5681 | 0.5326 | 0.0003 | 0.0006 | 0.0013 | 0.0134 | 0.0759 | 0.1150 | 0.0717 | 0.1123 | 0.6096 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 803 | 843 | | 8078 | 37469 | 422.2 | 79.09 | 159.69 | 223.20 | 327 | 354 | 375 | 397 | 417 | 437 | 459 | 489 | 531 | 0.0317 | 1189 | 1.189 | 110.68 | 36.67 | 1 | 0.0326 | 263 | 0.0007 | 56.32 | 7.529 | 0.1530 | 184520.0 | 83400000 | 38900000000 | 18700000000000 | 0.4100 | 0.2411 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0026 | 0.0001 | 0.0130 | 0.0004 | 0.0471 | 0.0139 | 0.1043 | 0.0293 | 0.1147 | 0.0226 | 0.1480 | 0.0455 | 0.5695 | 0.8882 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0050 | 0.0000 | 0.0239 | 0.0107 | 0.0515 | 0.0209 | 0.0493 | 0.0112 | 0.0688 | 0.0227 | 0.8000 | 0.9344 | 0.0074 | 0.0206 | 0.0033 | 0.0155 | 0.0294 | 0.0722 | 0.0711 | 0.1598 | 0.1266 | 0.2268 | 0.1585 | 0.1701 | 0.1152 | 0.1495 | 0.1479 | 0.0979 | 0.3407 | 0.0876 | 0.0005 | 0.0054 | 0.0099 | 0.0311 | 0.0677 | 0.1022 | 0.1066 | 0.1196 | 0.5569 | 8 | 12 | 18 | 34 | 59 | 102 | 172 | 277 | 460 | 0.0551 | 26.43 | 5.339 | 0.4890 | 75319.8 | 53300000 | 47300000000 | 49000000000000 | 0.3610 | 0.2741 | 0.0647 | 0.0026 | 0.2087 | 0.0190 | 0.2734 | 0.1221 | 0.1568 | 0.1521 | 0.1237 | 0.2054 | 0.0877 | 0.1850 | 0.0465 | 0.1224 | 0.0270 | 0.0989 | 0.0115 | 0.0926 | 0.0006 | 0.0004 | 0.0007 | 0.0010 | 0.0031 | 0.0025 | 0.0146 | 0.0116 | 0.0594 | 0.0555 | 0.0986 | 0.0841 | 0.0693 | 0.0619 | 0.0969 | 0.0912 | 0.6568 | 0.6917 | 0.0009 | 0.0003 | 0.0015 | 0.0012 | 0.0039 | 0.0068 | 0.0169 | 0.0173 | 0.0767 | 0.0907 | 0.1116 | 0.1149 | 0.0824 | 0.0817 | 0.1129 | 0.1235 | 0.5932 | 0.5636 | 0.0006 | 0.0018 | 0.0039 | 0.0139 | 0.0709 | 0.1068 | 0.0718 | 0.1079 | 0.6224 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 972 | 177 | | 395 | 12546 | 117.2 | 19.48 | 22.21 | 93.56 | 93 | 98 | 104 | 109 | 113 | 121 | 128 | 137 | 146 | 0.0524 | 657 | 1.105 | 42.05 | 12.04 | 0 | 0.2380 | 94 | 0.0471 | 0.93 | 3.300 | 0.6696 | 14103.0 | 1740000 | 221000000 | 28700000000 | 0.3949 | 0.2407 | 0.0000 | 0.0000 | 0.0102 | 0.0000 | 0.0136 | 0.0000 | 0.0374 | 0.0127 | 0.0646 | 0.0433 | 0.1224 | 0.0738 | 0.1327 | 0.0585 | 0.1565 | 0.0916 | 0.4626 | 0.7201 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0085 | 0.0000 | 0.0254 | 0.0127 | 0.0366 | 0.0430 | 0.0732 | 0.0734 | 0.0704 | 0.0532 | 0.0789 | 0.0658 | 0.7042 | 0.7519 | 0.0000 | 0.0000 | 0.0164 | 1.0000 | 0.0492 | 0.0000 | 0.0820 | 0.0000 | 0.0984 | 0.0000 | 0.1639 | 0.0000 | 0.1148 | 0.0000 | 0.1967 | 0.0000 | 0.2787 | 0.0000 | 0.0055 | 0.0055 | 0.0000 | 0.0497 | 0.0552 | 0.0718 | 0.0939 | 0.0939 | 0.6243 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 14 | 0.1205 | 3.55 | 1.534 | 0.4274 | 9246.7 | 8900000 | 10500000000 | 13500000000000 | 0.4645 | 0.1926 | 0.0604 | 0.1758 | 0.1758 | 0.0687 | 0.2582 | 0.0929 | 0.3462 | 0.1414 | 0.1099 | 0.1980 | 0.0385 | 0.1737 | 0.0110 | 0.0747 | 0.0000 | 0.0485 | 0.0000 | 0.0263 | 0.0000 | 0.0672 | 0.0020 | 0.0227 | 0.0099 | 0.0180 | 0.0159 | 0.0164 | 0.0556 | 0.0469 | 0.0724 | 0.0618 | 0.0764 | 0.0641 | 0.1022 | 0.0821 | 0.6657 | 0.6208 | 0.0024 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0026 | 0.0182 | 0.0140 | 0.0654 | 0.0727 | 0.0956 | 0.0969 | 0.0690 | 0.0625 | 0.0920 | 0.0982 | 0.6550 | 0.6531 | 0.0000 | 0.0022 | 0.0065 | 0.0196 | 0.0577 | 0.0882 | 0.0719 | 0.0882 | 0.6656 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 290 | 147 | | 6040 | 9656 | 458.9 | 90.94 | 116.43 | 141.69 | 320 | 377 | 416 | 448 | 476 | 496 | 516 | 535 | 564 | 0.0814 | 786 | 0.959 | 113.89 | 38.05 | 3 | 0.0513 | 310 | 0.0010 | 25.64 | 7.209 | 0.2429 | 218861.0 | 108000000 | 54400000000 | 28000000000000 | 0.4152 | 0.2180 | 0.0005 | 0.0000 | 0.0019 | 0.0003 | 0.0044 | 0.0003 | 0.0102 | 0.0015 | 0.0333 | 0.0148 | 0.0643 | 0.0297 | 0.0578 | 0.0191 | 0.0881 | 0.0275 | 0.7395 | 0.9067 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0012 | 0.0002 | 0.0026 | 0.0009 | 0.0174 | 0.0138 | 0.0319 | 0.0281 | 0.0218 | 0.0148 | 0.0325 | 0.0215 | 0.8926 | 0.9203 | 0.0108 | 0.0476 | 0.0084 | 0.0476 | 0.0251 | 0.1190 | 0.0514 | 0.0952 | 0.0825 | 0.2381 | 0.1172 | 0.0952 | 0.0921 | 0.1905 | 0.1077 | 0.0952 | 0.5048 | 0.0714 | 0.0003 | 0.0018 | 0.0041 | 0.0097 | 0.0264 | 0.0364 | 0.0416 | 0.0630 | 0.8168 | 13 | 18 | 27 | 38 | 53 | 77 | 124 | 203 | 323 | 0.0304 | 16.12 | 5.130 | 0.4988 | 33628.8 | 14200000 | 7210000000 | 4150000000000 | 0.4981 | 0.1590 | 0.0724 | 0.0035 | 0.2453 | 0.0225 | 0.2909 | 0.1207 | 0.1890 | 0.1819 | 0.1206 | 0.2159 | 0.0456 | 0.1813 | 0.0214 | 0.1207 | 0.0107 | 0.0924 | 0.0040 | 0.0612 | 0.0006 | 0.0007 | 0.0032 | 0.0022 | 0.0044 | 0.0063 | 0.0247 | 0.0243 | 0.0831 | 0.0762 | 0.1064 | 0.0919 | 0.0657 | 0.0672 | 0.1041 | 0.1014 | 0.6078 | 0.6299 | 0.0011 | 0.0000 | 0.0045 | 0.0059 | 0.0074 | 0.0121 | 0.0364 | 0.0422 | 0.0961 | 0.0945 | 0.1088 | 0.1225 | 0.0831 | 0.0895 | 0.1184 | 0.1171 | 0.5442 | 0.5161 | 0.0013 | 0.0016 | 0.0069 | 0.0310 | 0.0844 | 0.1105 | 0.0719 | 0.1049 | 0.5874 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1226 | 292 | | 1447 | 9024 | 65.1 | 24.28 | 181.44 | 210.82 | 35 | 44 | 51 | 57 | 63 | 69 | 76 | 85 | 96 | 0.0659 | 595 | 0.521 | 83.49 | 16.03 | 5 | 0.1714 | 248 | 0.0021 | 31.10 | 6.361 | 0.2003 | 4823.6 | 400876 | 37000000 | 3760000000 | 0.3867 | 0.2406 | 0.0000 | 0.0000 | 0.0116 | 0.0000 | 0.0198 | 0.0028 | 0.0843 | 0.0170 | 0.1802 | 0.0405 | 0.2215 | 0.1008 | 0.1884 | 0.1329 | 0.1818 | 0.1951 | 0.1124 | 0.5108 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0016 | 0.0109 | 0.0095 | 0.0465 | 0.0247 | 0.0812 | 0.0366 | 0.0663 | 0.0461 | 0.1238 | 0.0700 | 0.6693 | 0.8115 | 0.0049 | 0.0255 | 0.0099 | 0.0204 | 0.0025 | 0.0510 | 0.0765 | 0.1071 | 0.1284 | 0.1837 | 0.1778 | 0.1735 | 0.1654 | 0.1173 | 0.1407 | 0.1378 | 0.2938 | 0.1837 | 0.0015 | 0.0029 | 0.0059 | 0.0322 | 0.1025 | 0.1259 | 0.1127 | 0.1347 | 0.4817 | 19 | 26 | 41 | 64 | 97 | 142 | 205 | 308 | 477 | 0.0338 | 9.96 | 5.000 | 0.5659 | 77361.5 | 47900000 | 36100000000 | 30600000000000 | 0.5191 | 0.1524 | 0.0220 | 0.0015 | 0.0828 | 0.0094 | 0.1118 | 0.0342 | 0.1577 | 0.0768 | 0.2126 | 0.1412 | 0.1427 | 0.1684 | 0.1228 | 0.1273 | 0.0918 | 0.1446 | 0.0559 | 0.2967 | 0.0006 | 0.0005 | 0.0025 | 0.0012 | 0.0034 | 0.0009 | 0.0104 | 0.0092 | 0.0533 | 0.0431 | 0.0855 | 0.0726 | 0.0676 | 0.0528 | 0.0917 | 0.0820 | 0.6851 | 0.7378 | 0.0008 | 0.0013 | 0.0027 | 0.0022 | 0.0059 | 0.0040 | 0.0164 | 0.0211 | 0.0632 | 0.0723 | 0.1096 | 0.1159 | 0.0780 | 0.0858 | 0.1166 | 0.1204 | 0.6069 | 0.5768 | 0.0003 | 0.0020 | 0.0043 | 0.0143 | 0.0627 | 0.0953 | 0.0720 | 0.1040 | 0.6450 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1164 | 748 | | 6717 | 22463 | 231.2 | 47.47 | 136.57 | 200.73 | 173 | 191 | 204 | 215 | 227 | 239 | 252 | 268 | 296 | 0.0526 | 1181 | 0.934 | 159.62 | 41.01 | 1 | 0.0582 | 391 | 0.0009 | 55.53 | 7.264 | 0.1600 | 55703.1 | 14000000 | 3650000000 | 990000000000 | 0.4604 | 0.1920 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0003 | 0.0127 | 0.0008 | 0.0689 | 0.0184 | 0.1261 | 0.0348 | 0.1510 | 0.0342 | 0.1834 | 0.0606 | 0.4552 | 0.8508 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0001 | 0.0050 | 0.0003 | 0.0314 | 0.0132 | 0.0557 | 0.0204 | 0.0683 | 0.0150 | 0.0944 | 0.0288 | 0.7437 | 0.9222 | 0.0094 | 0.0220 | 0.0122 | 0.0293 | 0.0300 | 0.0549 | 0.0880 | 0.1172 | 0.1451 | 0.2125 | 0.1751 | 0.1978 | 0.1170 | 0.1026 | 0.1517 | 0.1172 | 0.2715 | 0.1465 | 0.0006 | 0.0029 | 0.0095 | 0.0350 | 0.1008 | 0.1316 | 0.1272 | 0.1459 | 0.4464 | 8 | 10 | 11 | 13 | 17 | 50 | 153 | 289 | 440 | 0.1678 | 32.49 | 4.522 | 0.5734 | 58941.1 | 34500000 | 24900000000 | 22000000000000 | 0.4912 | 0.1551 | 0.1222 | 0.0039 | 0.3163 | 0.0380 | 0.3182 | 0.2866 | 0.1251 | 0.2349 | 0.0660 | 0.1696 | 0.0394 | 0.1194 | 0.0089 | 0.0653 | 0.0039 | 0.0443 | 0.0000 | 0.0380 | 0.0000 | 0.0000 | 0.0005 | 0.0001 | 0.0001 | 0.0002 | 0.0044 | 0.0063 | 0.0495 | 0.0387 | 0.0788 | 0.0683 | 0.0580 | 0.0512 | 0.1014 | 0.0836 | 0.7073 | 0.7515 | 0.0000 | 0.0003 | 0.0003 | 0.0005 | 0.0002 | 0.0016 | 0.0104 | 0.0097 | 0.0555 | 0.0675 | 0.1057 | 0.1099 | 0.0760 | 0.0890 | 0.1243 | 0.1280 | 0.6276 | 0.5934 | 0.0000 | 0.0006 | 0.0006 | 0.0083 | 0.0528 | 0.0884 | 0.0720 | 0.1141 | 0.6632 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 666 | 842 | | 12884 | 27221 | 219.0 | 58.92 | 118.73 | 205.47 | 152 | 171 | 185 | 199 | 212 | 227 | 245 | 268 | 298 | 0.0499 | 1359 | 0.808 | 193.62 | 44.05 | 2 | 0.0354 | 456 | 0.0008 | 46.64 | 7.460 | 0.1768 | 51441.8 | 12900000 | 3430000000 | 964000000000 | 0.4180 | 0.2281 | 0.0003 | 0.0001 | 0.0020 | 0.0000 | 0.0075 | 0.0004 | 0.0271 | 0.0027 | 0.0783 | 0.0206 | 0.1403 | 0.0412 | 0.1412 | 0.0459 | 0.1709 | 0.0684 | 0.4325 | 0.8207 | 0.0001 | 0.0000 | 0.0013 | 0.0000 | 0.0023 | 0.0000 | 0.0103 | 0.0014 | 0.0303 | 0.0115 | 0.0505 | 0.0181 | 0.0596 | 0.0180 | 0.0775 | 0.0275 | 0.7681 | 0.9236 | 0.0028 | 0.0068 | 0.0028 | 0.0184 | 0.0137 | 0.0261 | 0.0439 | 0.0812 | 0.0847 | 0.1285 | 0.1612 | 0.1865 | 0.1135 | 0.0889 | 0.1377 | 0.1449 | 0.4398 | 0.3188 | 0.0017 | 0.0044 | 0.0094 | 0.0269 | 0.0584 | 0.0906 | 0.0952 | 0.1178 | 0.5957 | 12 | 14 | 16 | 19 | 23 | 35 | 81 | 186 | 369 | 0.1090 | 28.98 | 4.298 | 0.6029 | 56311.6 | 43400000 | 43600000000 | 52400000000000 | 0.4887 | 0.1540 | 0.1380 | 0.0057 | 0.3027 | 0.0505 | 0.2534 | 0.2149 | 0.1170 | 0.1937 | 0.0888 | 0.2013 | 0.0605 | 0.1398 | 0.0282 | 0.0765 | 0.0105 | 0.0629 | 0.0008 | 0.0547 | 0.0000 | 0.0004 | 0.0018 | 0.0008 | 0.0016 | 0.0015 | 0.0149 | 0.0108 | 0.0607 | 0.0575 | 0.0912 | 0.0799 | 0.0683 | 0.0568 | 0.1015 | 0.0892 | 0.6600 | 0.7031 | 0.0005 | 0.0000 | 0.0008 | 0.0012 | 0.0040 | 0.0058 | 0.0208 | 0.0226 | 0.0784 | 0.0804 | 0.1103 | 0.1258 | 0.0842 | 0.0911 | 0.1132 | 0.1227 | 0.5879 | 0.5503 | 0.0004 | 0.0011 | 0.0027 | 0.0160 | 0.0680 | 0.1060 | 0.0721 | 0.1158 | 0.6178 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 980 | 154 | | 9107 | 15265 | 478.7 | 85.92 | 198.56 | 276.33 | 358 | 401 | 437 | 463 | 485 | 506 | 527 | 552 | 588 | 0.0735 | 1122 | 0.982 | 84.40 | 29.43 | 4 | 0.0254 | 231 | 0.0010 | 22.23 | 7.221 | 0.2396 | 236580.0 | 120000000 | 62600000000 | 33300000000000 | 0.4434 | 0.2060 | 0.0008 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0001 | 0.0113 | 0.0006 | 0.0270 | 0.0119 | 0.0415 | 0.0194 | 0.0463 | 0.0139 | 0.0694 | 0.0222 | 0.7980 | 0.9319 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0012 | 0.0000 | 0.0040 | 0.0006 | 0.0131 | 0.0117 | 0.0209 | 0.0179 | 0.0208 | 0.0114 | 0.0297 | 0.0180 | 0.9101 | 0.9405 | 0.0083 | 0.0294 | 0.0173 | 0.0588 | 0.0273 | 0.0882 | 0.0380 | 0.2059 | 0.0512 | 0.2353 | 0.0760 | 0.1471 | 0.0950 | 0.1471 | 0.1230 | 0.0588 | 0.5640 | 0.0294 | 0.0010 | 0.0031 | 0.0072 | 0.0149 | 0.0256 | 0.0345 | 0.0450 | 0.0565 | 0.8122 | 11 | 14 | 19 | 34 | 73 | 133 | 224 | 349 | 565 | 0.0491 | 47.73 | 5.568 | 0.4783 | 115779.0 | 101000000 | 112000000000 | 147000000000000 | 0.3844 | 0.2395 | 0.0410 | 0.0015 | 0.1640 | 0.0173 | 0.2243 | 0.0857 | 0.1640 | 0.1357 | 0.1446 | 0.1765 | 0.1106 | 0.1922 | 0.0789 | 0.1361 | 0.0472 | 0.1023 | 0.0255 | 0.1526 | 0.0004 | 0.0003 | 0.0011 | 0.0014 | 0.0023 | 0.0048 | 0.0151 | 0.0114 | 0.0519 | 0.0457 | 0.0774 | 0.0628 | 0.0614 | 0.0517 | 0.0854 | 0.0750 | 0.7052 | 0.7469 | 0.0002 | 0.0005 | 0.0018 | 0.0031 | 0.0067 | 0.0089 | 0.0220 | 0.0270 | 0.0687 | 0.0786 | 0.1061 | 0.1226 | 0.0859 | 0.0881 | 0.1079 | 0.1098 | 0.6006 | 0.5613 | 0.0004 | 0.0012 | 0.0052 | 0.0181 | 0.0596 | 0.0890 | 0.0721 | 0.1031 | 0.6512 |