High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1030 | 654 | | 4733 | 10425 | 467.9 | 107.24 | 95.77 | 122.81 | 345 | 379 | 404 | 428 | 451 | 479 | 509 | 550 | 613 | 0.0706 | 736 | 0.617 | 150.66 | 41.15 | 1 | 0.0909 | 430 | 0.0008 | 55.01 | 7.358 | 0.1623 | 230448.0 | 120000000 | 65300000000 | 37500000000000 | 0.3787 | 0.2634 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0007 | 0.0134 | 0.0009 | 0.0647 | 0.0210 | 0.1390 | 0.0495 | 0.1451 | 0.0401 | 0.1678 | 0.0472 | 0.4677 | 0.8406 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0006 | 0.0057 | 0.0004 | 0.0302 | 0.0145 | 0.0629 | 0.0288 | 0.0577 | 0.0177 | 0.0847 | 0.0228 | 0.7570 | 0.9150 | 0.0023 | 0.0000 | 0.0070 | 0.0000 | 0.0151 | 0.0201 | 0.0568 | 0.0936 | 0.1230 | 0.1472 | 0.1647 | 0.2107 | 0.0974 | 0.1037 | 0.1334 | 0.1171 | 0.4002 | 0.3077 | 0.0005 | 0.0024 | 0.0063 | 0.0250 | 0.0794 | 0.1414 | 0.1034 | 0.1255 | 0.5161 | 8 | 10 | 12 | 16 | 31 | 66 | 119 | 187 | 269 | 0.0567 | 15.85 | 4.921 | 0.5294 | 24254.7 | 8620000 | 3790000000 | 1970000000000 | 0.5285 | 0.1189 | 0.0542 | 0.0020 | 0.2045 | 0.0127 | 0.3074 | 0.1029 | 0.1864 | 0.1470 | 0.1140 | 0.2238 | 0.0695 | 0.2285 | 0.0320 | 0.1142 | 0.0209 | 0.0788 | 0.0111 | 0.0902 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0003 | 0.0011 | 0.0095 | 0.0066 | 0.0504 | 0.0403 | 0.0831 | 0.0816 | 0.0652 | 0.0504 | 0.0967 | 0.0809 | 0.6944 | 0.7391 | 0.0000 | 0.0000 | 0.0013 | 0.0003 | 0.0019 | 0.0021 | 0.0107 | 0.0164 | 0.0630 | 0.0649 | 0.1047 | 0.1238 | 0.0740 | 0.0795 | 0.1160 | 0.1196 | 0.6286 | 0.5934 | 0.0000 | 0.0003 | 0.0014 | 0.0107 | 0.0546 | 0.0976 | 0.0658 | 0.1029 | 0.6668 | ||
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 637 | 251 | | 4831 | 6157 | 434.9 | 144.34 | 87.99 | 128.76 | 226 | 293 | 353 | 413 | 455 | 489 | 520 | 554 | 622 | 0.1176 | 724 | 0.741 | 143.63 | 44.91 | 2 | 0.0909 | 439 | 0.0009 | 28.38 | 7.266 | 0.2359 | 209951.0 | 109000000 | 59200000000 | 33500000000000 | 0.3927 | 0.2352 | 0.0015 | 0.0000 | 0.0035 | 0.0000 | 0.0050 | 0.0003 | 0.0179 | 0.0042 | 0.0601 | 0.0282 | 0.1118 | 0.0434 | 0.0860 | 0.0299 | 0.1143 | 0.0511 | 0.5999 | 0.8429 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0002 | 0.0023 | 0.0022 | 0.0216 | 0.0210 | 0.0347 | 0.0259 | 0.0213 | 0.0213 | 0.0361 | 0.0291 | 0.8835 | 0.9002 | 0.0007 | 0.0000 | 0.0035 | 0.0000 | 0.0084 | 0.0000 | 0.0169 | 0.0000 | 0.0443 | 0.0000 | 0.0718 | 0.0000 | 0.0577 | 0.0000 | 0.0809 | 0.0000 | 0.7157 | 1.0000 | 0.0000 | 0.0007 | 0.0011 | 0.0048 | 0.0257 | 0.0432 | 0.0313 | 0.0555 | 0.8375 | 9 | 11 | 13 | 18 | 26 | 42 | 87 | 147 | 262 | 0.1247 | 11.17 | 3.769 | 0.6386 | 24317.8 | 10200000 | 5220000000 | 3080000000000 | 0.5729 | 0.1008 | 0.0398 | 0.0089 | 0.1273 | 0.0316 | 0.1777 | 0.0671 | 0.1751 | 0.0886 | 0.1565 | 0.1696 | 0.1008 | 0.1810 | 0.0955 | 0.1405 | 0.0822 | 0.1329 | 0.0451 | 0.1797 | 0.0005 | 0.0004 | 0.0020 | 0.0027 | 0.0025 | 0.0027 | 0.0094 | 0.0093 | 0.0480 | 0.0409 | 0.0762 | 0.0721 | 0.0574 | 0.0503 | 0.0826 | 0.0730 | 0.7216 | 0.7486 | 0.0000 | 0.0007 | 0.0018 | 0.0000 | 0.0030 | 0.0048 | 0.0152 | 0.0213 | 0.0626 | 0.0810 | 0.1027 | 0.1071 | 0.0699 | 0.1009 | 0.1240 | 0.1263 | 0.6207 | 0.5580 | 0.0000 | 0.0005 | 0.0016 | 0.0114 | 0.0565 | 0.0864 | 0.0549 | 0.1010 | 0.6877 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 599 | 374 | | 6551 | 17041 | 267.6 | 66.19 | 105.49 | 114.89 | 194 | 211 | 226 | 241 | 255 | 271 | 293 | 319 | 363 | 0.0596 | 1016 | 1.053 | 98.33 | 35.17 | 1 | 0.0400 | 262 | 0.0008 | 56.30 | 7.438 | 0.1617 | 75974.1 | 22900000 | 7350000000 | 2490000000000 | 0.4000 | 0.2484 | 0.0008 | 0.0000 | 0.0034 | 0.0003 | 0.0047 | 0.0005 | 0.0238 | 0.0032 | 0.0663 | 0.0219 | 0.1305 | 0.0441 | 0.1370 | 0.0413 | 0.1859 | 0.0657 | 0.4477 | 0.8230 | 0.0004 | 0.0000 | 0.0022 | 0.0000 | 0.0022 | 0.0000 | 0.0124 | 0.0008 | 0.0271 | 0.0139 | 0.0574 | 0.0225 | 0.0594 | 0.0169 | 0.0936 | 0.0300 | 0.7454 | 0.9159 | 0.0048 | 0.0079 | 0.0072 | 0.0099 | 0.0183 | 0.0217 | 0.0462 | 0.0791 | 0.0916 | 0.1462 | 0.1371 | 0.1798 | 0.1139 | 0.1146 | 0.1394 | 0.1462 | 0.4414 | 0.2945 | 0.0018 | 0.0029 | 0.0058 | 0.0282 | 0.0762 | 0.1181 | 0.0986 | 0.1203 | 0.5482 | 12 | 15 | 20 | 33 | 58 | 96 | 143 | 192 | 256 | 0.0374 | 9.37 | 5.007 | 0.5330 | 24326.7 | 7980000 | 3300000000 | 1610000000000 | 0.5431 | 0.1194 | 0.0353 | 0.0003 | 0.2286 | 0.0100 | 0.3382 | 0.1134 | 0.1429 | 0.1621 | 0.1127 | 0.2268 | 0.0793 | 0.2001 | 0.0390 | 0.1222 | 0.0157 | 0.0806 | 0.0082 | 0.0845 | 0.0001 | 0.0000 | 0.0003 | 0.0005 | 0.0014 | 0.0004 | 0.0096 | 0.0081 | 0.0557 | 0.0459 | 0.1000 | 0.0861 | 0.0671 | 0.0552 | 0.0956 | 0.0849 | 0.6703 | 0.7189 | 0.0002 | 0.0006 | 0.0016 | 0.0026 | 0.0019 | 0.0060 | 0.0157 | 0.0227 | 0.0714 | 0.0843 | 0.1314 | 0.1389 | 0.0812 | 0.0897 | 0.1127 | 0.1180 | 0.5839 | 0.5372 | 0.0002 | 0.0008 | 0.0031 | 0.0103 | 0.0642 | 0.1150 | 0.0771 | 0.1071 | 0.6223 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1069 | 128 | | 2783 | 11256 | 51.7 | 18.54 | 103.66 | 116.84 | 30 | 35 | 40 | 45 | 50 | 54 | 60 | 67 | 78 | 0.0861 | 969 | 0.603 | 152.75 | 27.51 | 6 | 0.1347 | 375 | 0.0052 | 9.08 | 5.547 | 0.3491 | 3018.8 | 195743 | 13900000 | 1050000000 | 0.4330 | 0.1802 | 0.0026 | 0.0005 | 0.0071 | 0.0000 | 0.0556 | 0.0035 | 0.1412 | 0.0262 | 0.1571 | 0.0657 | 0.1986 | 0.1226 | 0.1297 | 0.1409 | 0.1262 | 0.1557 | 0.1818 | 0.4849 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0011 | 0.0017 | 0.0228 | 0.0132 | 0.0565 | 0.0405 | 0.1146 | 0.0653 | 0.0880 | 0.0690 | 0.1222 | 0.0860 | 0.5932 | 0.7243 | 0.0071 | 0.0025 | 0.0085 | 0.0354 | 0.0297 | 0.0303 | 0.0621 | 0.0581 | 0.1285 | 0.1465 | 0.1370 | 0.1641 | 0.1314 | 0.1237 | 0.1427 | 0.1717 | 0.3531 | 0.2677 | 0.0008 | 0.0000 | 0.0110 | 0.0432 | 0.0856 | 0.1540 | 0.1163 | 0.1406 | 0.4485 | 13 | 17 | 24 | 38 | 58 | 83 | 121 | 176 | 261 | 0.0237 | 15.67 | 5.256 | 0.4584 | 24394.3 | 8520000 | 3730000000 | 1900000000000 | 0.5135 | 0.1676 | 0.0460 | 0.0031 | 0.1957 | 0.0140 | 0.2492 | 0.0815 | 0.1672 | 0.1444 | 0.1530 | 0.1870 | 0.0962 | 0.1917 | 0.0552 | 0.1269 | 0.0268 | 0.1211 | 0.0109 | 0.1304 | 0.0004 | 0.0007 | 0.0020 | 0.0011 | 0.0080 | 0.0037 | 0.0214 | 0.0182 | 0.0764 | 0.0588 | 0.1256 | 0.1088 | 0.0857 | 0.0785 | 0.1129 | 0.1069 | 0.5677 | 0.6232 | 0.0021 | 0.0004 | 0.0030 | 0.0071 | 0.0118 | 0.0139 | 0.0300 | 0.0363 | 0.0919 | 0.0879 | 0.1475 | 0.1584 | 0.1001 | 0.0993 | 0.1186 | 0.1217 | 0.4948 | 0.4751 | 0.0005 | 0.0031 | 0.0065 | 0.0265 | 0.0749 | 0.1471 | 0.0884 | 0.1191 | 0.5339 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 156 | 594 | | 9080 | 15618 | 311.0 | 68.29 | 98.46 | 121.64 | 229 | 251 | 270 | 288 | 305 | 324 | 344 | 367 | 401 | 0.0788 | 1231 | 0.960 | 135.72 | 35.01 | 1 | 0.0352 | 320 | 0.0013 | 28.86 | 6.929 | 0.2122 | 101409.0 | 34600000 | 12300000000 | 4590000000000 | 0.4537 | 0.2035 | 0.0010 | 0.0000 | 0.0019 | 0.0001 | 0.0068 | 0.0009 | 0.0222 | 0.0025 | 0.0705 | 0.0167 | 0.1362 | 0.0410 | 0.1452 | 0.0416 | 0.1613 | 0.0640 | 0.4548 | 0.8331 | 0.0007 | 0.0000 | 0.0005 | 0.0000 | 0.0027 | 0.0006 | 0.0099 | 0.0020 | 0.0293 | 0.0115 | 0.0662 | 0.0283 | 0.0633 | 0.0223 | 0.0823 | 0.0364 | 0.7452 | 0.8989 | 0.0056 | 0.0027 | 0.0124 | 0.0318 | 0.0204 | 0.0637 | 0.0667 | 0.1141 | 0.1248 | 0.2042 | 0.1513 | 0.1485 | 0.1328 | 0.0716 | 0.1575 | 0.1300 | 0.3286 | 0.2334 | 0.0007 | 0.0030 | 0.0096 | 0.0287 | 0.0674 | 0.1168 | 0.1070 | 0.1261 | 0.5408 | 12 | 14 | 17 | 23 | 41 | 74 | 118 | 173 | 260 | 0.0390 | 25.52 | 5.297 | 0.4490 | 24490.2 | 9030000 | 4150000000 | 2200000000000 | 0.5460 | 0.1292 | 0.0690 | 0.0018 | 0.1999 | 0.0187 | 0.2994 | 0.1257 | 0.1613 | 0.1617 | 0.1323 | 0.2185 | 0.0814 | 0.1892 | 0.0378 | 0.1186 | 0.0145 | 0.0981 | 0.0044 | 0.0678 | 0.0002 | 0.0003 | 0.0012 | 0.0006 | 0.0031 | 0.0027 | 0.0151 | 0.0124 | 0.0691 | 0.0593 | 0.1090 | 0.0934 | 0.0785 | 0.0690 | 0.1141 | 0.1000 | 0.6096 | 0.6622 | 0.0011 | 0.0015 | 0.0023 | 0.0025 | 0.0079 | 0.0093 | 0.0234 | 0.0284 | 0.0888 | 0.0944 | 0.1239 | 0.1444 | 0.0960 | 0.0946 | 0.1298 | 0.1284 | 0.5268 | 0.4966 | 0.0002 | 0.0022 | 0.0039 | 0.0202 | 0.0788 | 0.1208 | 0.0884 | 0.1238 | 0.5618 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 370 | 294 | | 5485 | 10563 | 124.0 | 34.56 | 117.76 | 103.27 | 86 | 95 | 103 | 110 | 117 | 126 | 136 | 150 | 170 | 0.0846 | 894 | 0.963 | 95.52 | 33.42 | 1 | 0.0500 | 274 | 0.0022 | 24.84 | 6.477 | 0.2498 | 16564.2 | 2390000 | 374000000 | 63000000000 | 0.4073 | 0.2446 | 0.0010 | 0.0000 | 0.0044 | 0.0000 | 0.0153 | 0.0012 | 0.0435 | 0.0059 | 0.1084 | 0.0244 | 0.1855 | 0.0590 | 0.1804 | 0.0658 | 0.1696 | 0.1047 | 0.2919 | 0.7390 | 0.0002 | 0.0000 | 0.0017 | 0.0000 | 0.0066 | 0.0000 | 0.0172 | 0.0021 | 0.0434 | 0.0153 | 0.0767 | 0.0283 | 0.0797 | 0.0280 | 0.0995 | 0.0527 | 0.6749 | 0.8736 | 0.0026 | 0.0083 | 0.0097 | 0.0145 | 0.0150 | 0.0455 | 0.0607 | 0.1074 | 0.1514 | 0.1653 | 0.1752 | 0.2045 | 0.1294 | 0.1157 | 0.1488 | 0.1322 | 0.3072 | 0.2066 | 0.0026 | 0.0047 | 0.0129 | 0.0331 | 0.0786 | 0.1301 | 0.1108 | 0.1447 | 0.4826 | 16 | 26 | 41 | 63 | 88 | 117 | 152 | 200 | 268 | 0.0059 | 25.56 | 6.335 | 0.3474 | 24530.7 | 6760000 | 2220000000 | 822000000000 | 0.5829 | 0.1325 | 0.0182 | 0.0019 | 0.0846 | 0.0051 | 0.1973 | 0.0296 | 0.1849 | 0.0819 | 0.1784 | 0.1674 | 0.1426 | 0.2027 | 0.0990 | 0.1609 | 0.0736 | 0.1539 | 0.0215 | 0.1966 | 0.0002 | 0.0007 | 0.0018 | 0.0013 | 0.0042 | 0.0037 | 0.0149 | 0.0111 | 0.0556 | 0.0427 | 0.0899 | 0.0705 | 0.0803 | 0.0677 | 0.1118 | 0.0992 | 0.6413 | 0.7031 | 0.0011 | 0.0011 | 0.0040 | 0.0021 | 0.0078 | 0.0088 | 0.0221 | 0.0284 | 0.0709 | 0.0935 | 0.1183 | 0.1285 | 0.1002 | 0.1113 | 0.1330 | 0.1373 | 0.5425 | 0.4891 | 0.0010 | 0.0021 | 0.0040 | 0.0209 | 0.0659 | 0.0949 | 0.0885 | 0.1221 | 0.6005 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 797 | 276 | | 3081 | 14857 | 257.1 | 73.60 | 95.99 | 124.19 | 175 | 187 | 202 | 218 | 241 | 266 | 296 | 325 | 367 | 0.0703 | 1045 | 0.709 | 60.54 | 16.03 | 2 | 0.0568 | 175 | 0.0097 | 3.01 | 5.047 | 0.5308 | 71538.3 | 21500000 | 6880000000 | 2330000000000 | 0.3683 | 0.2682 | 0.0023 | 0.0000 | 0.0053 | 0.0000 | 0.0107 | 0.0015 | 0.0328 | 0.0041 | 0.0710 | 0.0354 | 0.1154 | 0.0479 | 0.1054 | 0.0420 | 0.1398 | 0.0593 | 0.5172 | 0.8099 | 0.0014 | 0.0000 | 0.0019 | 0.0000 | 0.0043 | 0.0007 | 0.0125 | 0.0013 | 0.0288 | 0.0202 | 0.0389 | 0.0276 | 0.0408 | 0.0189 | 0.0504 | 0.0315 | 0.8209 | 0.8998 | 0.0013 | 0.0000 | 0.0000 | 0.0111 | 0.0090 | 0.0028 | 0.0168 | 0.0306 | 0.0530 | 0.0889 | 0.0917 | 0.1306 | 0.0646 | 0.1139 | 0.0904 | 0.1500 | 0.6731 | 0.4722 | 0.0015 | 0.0015 | 0.0052 | 0.0126 | 0.0238 | 0.0535 | 0.0416 | 0.0558 | 0.8045 | 12 | 19 | 29 | 42 | 54 | 70 | 95 | 135 | 230 | 0.0663 | 4.54 | 3.869 | 0.7237 | 24635.6 | 11400000 | 7270000000 | 5520000000000 | 0.4425 | 0.1810 | 0.0092 | 0.0039 | 0.0252 | 0.0102 | 0.0406 | 0.0158 | 0.0729 | 0.0304 | 0.1237 | 0.0621 | 0.1566 | 0.0900 | 0.1494 | 0.0954 | 0.1869 | 0.1280 | 0.2356 | 0.5641 | 0.0025 | 0.0017 | 0.0033 | 0.0049 | 0.0040 | 0.0052 | 0.0113 | 0.0100 | 0.0302 | 0.0240 | 0.0458 | 0.0344 | 0.0473 | 0.0408 | 0.0691 | 0.0611 | 0.7864 | 0.8179 | 0.0008 | 0.0007 | 0.0034 | 0.0027 | 0.0059 | 0.0050 | 0.0163 | 0.0174 | 0.0487 | 0.0557 | 0.0704 | 0.0795 | 0.0637 | 0.0651 | 0.0789 | 0.0849 | 0.7118 | 0.6890 | 0.0011 | 0.0052 | 0.0059 | 0.0142 | 0.0363 | 0.0542 | 0.0582 | 0.0716 | 0.7533 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 854 | 856 | | 7221 | 14570 | 49.4 | 17.53 | 78.00 | 136.28 | 28 | 34 | 38 | 43 | 47 | 52 | 58 | 64 | 73 | 0.0925 | 1347 | 0.564 | 226.82 | 39.32 | 13 | 0.0867 | 626 | 0.0060 | 6.82 | 5.419 | 0.3768 | 2746.4 | 169000 | 11300000 | 819000000 | 0.4385 | 0.1979 | 0.0021 | 0.0002 | 0.0092 | 0.0013 | 0.0509 | 0.0036 | 0.1206 | 0.0209 | 0.1835 | 0.0519 | 0.1998 | 0.1171 | 0.1729 | 0.1192 | 0.1266 | 0.1517 | 0.1344 | 0.5342 | 0.0004 | 0.0000 | 0.0012 | 0.0005 | 0.0037 | 0.0013 | 0.0217 | 0.0112 | 0.0562 | 0.0266 | 0.0864 | 0.0540 | 0.0848 | 0.0579 | 0.1085 | 0.0691 | 0.6371 | 0.7796 | 0.0039 | 0.0097 | 0.0073 | 0.0154 | 0.0194 | 0.0328 | 0.0682 | 0.0936 | 0.1094 | 0.1380 | 0.1510 | 0.1979 | 0.1292 | 0.1342 | 0.1549 | 0.1467 | 0.3567 | 0.2317 | 0.0017 | 0.0026 | 0.0125 | 0.0408 | 0.0755 | 0.1098 | 0.1078 | 0.1329 | 0.5163 | 11 | 13 | 15 | 17 | 20 | 26 | 46 | 104 | 234 | 0.1860 | 10.58 | 3.510 | 0.6862 | 24655.2 | 13200000 | 8940000000 | 7000000000000 | 0.6410 | 0.1101 | 0.1548 | 0.0039 | 0.3289 | 0.0394 | 0.2946 | 0.2229 | 0.1131 | 0.2327 | 0.0565 | 0.2189 | 0.0298 | 0.1433 | 0.0134 | 0.0671 | 0.0074 | 0.0493 | 0.0015 | 0.0224 | 0.0008 | 0.0002 | 0.0008 | 0.0005 | 0.0032 | 0.0053 | 0.0201 | 0.0138 | 0.0823 | 0.0766 | 0.1173 | 0.0994 | 0.0839 | 0.0713 | 0.1284 | 0.1266 | 0.5631 | 0.6063 | 0.0003 | 0.0007 | 0.0023 | 0.0021 | 0.0058 | 0.0053 | 0.0229 | 0.0248 | 0.1011 | 0.1076 | 0.1308 | 0.1522 | 0.0995 | 0.0995 | 0.1485 | 0.1501 | 0.4889 | 0.4577 | 0.0000 | 0.0023 | 0.0053 | 0.0197 | 0.0978 | 0.1169 | 0.0934 | 0.1436 | 0.5211 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 857 | 519 | | 7896 | 25086 | 549.1 | 111.64 | 115.29 | 108.29 | 407 | 452 | 487 | 515 | 543 | 571 | 603 | 640 | 694 | 0.0453 | 1137 | 0.998 | 121.50 | 33.97 | 1 | 0.0384 | 303 | 0.0006 | 71.62 | 7.693 | 0.1462 | 313964.0 | 187000000 | 115000000000 | 73300000000000 | 0.4442 | 0.2062 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0000 | 0.0110 | 0.0013 | 0.0526 | 0.0162 | 0.1198 | 0.0335 | 0.1264 | 0.0258 | 0.1582 | 0.0429 | 0.5295 | 0.8802 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0000 | 0.0247 | 0.0109 | 0.0576 | 0.0223 | 0.0544 | 0.0138 | 0.0738 | 0.0246 | 0.7850 | 0.9284 | 0.0055 | 0.0067 | 0.0079 | 0.0134 | 0.0259 | 0.0235 | 0.0715 | 0.0705 | 0.1155 | 0.1779 | 0.1595 | 0.2315 | 0.1147 | 0.1409 | 0.1304 | 0.1342 | 0.3692 | 0.2013 | 0.0003 | 0.0021 | 0.0045 | 0.0279 | 0.0760 | 0.1244 | 0.0942 | 0.1323 | 0.5384 | 14 | 19 | 30 | 51 | 80 | 116 | 158 | 205 | 271 | 0.0163 | 18.42 | 5.849 | 0.4162 | 25016.0 | 7180000 | 2480000000 | 993000000000 | 0.4965 | 0.1507 | 0.0497 | 0.0008 | 0.2062 | 0.0128 | 0.2854 | 0.1255 | 0.1474 | 0.1729 | 0.1169 | 0.1868 | 0.0873 | 0.1793 | 0.0490 | 0.1096 | 0.0336 | 0.0972 | 0.0245 | 0.1151 | 0.0003 | 0.0000 | 0.0008 | 0.0004 | 0.0022 | 0.0018 | 0.0130 | 0.0103 | 0.0633 | 0.0528 | 0.1135 | 0.0937 | 0.0729 | 0.0627 | 0.1138 | 0.0990 | 0.6201 | 0.6793 | 0.0006 | 0.0004 | 0.0013 | 0.0031 | 0.0045 | 0.0078 | 0.0266 | 0.0355 | 0.0880 | 0.1026 | 0.1507 | 0.1609 | 0.0929 | 0.1075 | 0.1339 | 0.1393 | 0.5016 | 0.4429 | 0.0004 | 0.0013 | 0.0028 | 0.0194 | 0.0737 | 0.1338 | 0.0833 | 0.1256 | 0.5598 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 407 | 716 | | 7114 | 12770 | 534.1 | 94.65 | 61.96 | 146.06 | 380 | 451 | 508 | 534 | 555 | 577 | 594 | 611 | 633 | 0.0662 | 846 | 0.850 | 97.59 | 26.25 | 2 | 0.0417 | 297 | 0.0011 | 32.30 | 7.208 | 0.2276 | 294243.0 | 166000000 | 95600000000 | 55900000000000 | 0.4540 | 0.2027 | 0.0002 | 0.0001 | 0.0009 | 0.0006 | 0.0015 | 0.0003 | 0.0052 | 0.0017 | 0.0232 | 0.0121 | 0.0462 | 0.0176 | 0.0420 | 0.0150 | 0.0641 | 0.0232 | 0.8167 | 0.9294 | 0.0002 | 0.0001 | 0.0003 | 0.0006 | 0.0002 | 0.0003 | 0.0007 | 0.0017 | 0.0128 | 0.0121 | 0.0245 | 0.0176 | 0.0130 | 0.0150 | 0.0239 | 0.0232 | 0.9245 | 0.9294 | 0.0121 | 0.0000 | 0.0208 | 0.0000 | 0.0363 | 0.0000 | 0.0813 | 0.0000 | 0.1142 | 0.0000 | 0.1280 | 0.0000 | 0.1090 | 0.0000 | 0.1228 | 0.0000 | 0.3754 | 0.0000 | 0.0005 | 0.0014 | 0.0054 | 0.0119 | 0.0261 | 0.0428 | 0.0447 | 0.0612 | 0.8061 | 9 | 10 | 11 | 12 | 13 | 15 | 17 | 33 | 165 | 0.1905 | 3.26 | 2.362 | 0.6175 | 25171.9 | 16600000 | 13100000000 | 11600000000000 | 0.6507 | 0.0699 | 0.0193 | 0.0057 | 0.1322 | 0.0086 | 0.2204 | 0.0743 | 0.1736 | 0.1329 | 0.1267 | 0.2157 | 0.0909 | 0.1571 | 0.0716 | 0.0929 | 0.0661 | 0.1114 | 0.0992 | 0.2014 | 0.0000 | 0.0008 | 0.0009 | 0.0008 | 0.0031 | 0.0028 | 0.0098 | 0.0102 | 0.0459 | 0.0468 | 0.0570 | 0.0533 | 0.0459 | 0.0403 | 0.0731 | 0.0744 | 0.7643 | 0.7706 | 0.0011 | 0.0006 | 0.0021 | 0.0017 | 0.0069 | 0.0040 | 0.0133 | 0.0108 | 0.0436 | 0.0483 | 0.0760 | 0.0802 | 0.0452 | 0.0495 | 0.0803 | 0.0870 | 0.7315 | 0.7180 | 0.0005 | 0.0019 | 0.0048 | 0.0150 | 0.0446 | 0.0650 | 0.0509 | 0.0805 | 0.7368 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 201 | 479 | | 6474 | 26300 | 321.0 | 57.21 | 100.08 | 124.51 | 249 | 270 | 287 | 303 | 318 | 334 | 351 | 372 | 398 | 0.0455 | 1196 | 1.134 | 99.86 | 37.59 | 2 | 0.0394 | 255 | 0.0006 | 73.06 | 7.553 | 0.1323 | 106297.0 | 36300000 | 12700000000 | 4580000000000 | 0.4555 | 0.1968 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0030 | 0.0002 | 0.0144 | 0.0008 | 0.0453 | 0.0123 | 0.1133 | 0.0261 | 0.1258 | 0.0247 | 0.1709 | 0.0467 | 0.5257 | 0.8892 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0002 | 0.0069 | 0.0003 | 0.0227 | 0.0113 | 0.0501 | 0.0206 | 0.0538 | 0.0157 | 0.0774 | 0.0244 | 0.7881 | 0.9275 | 0.0044 | 0.0805 | 0.0187 | 0.0575 | 0.0430 | 0.1839 | 0.0926 | 0.0920 | 0.1599 | 0.3103 | 0.1985 | 0.1379 | 0.1279 | 0.0460 | 0.1709 | 0.0805 | 0.1841 | 0.0115 | 0.0010 | 0.0025 | 0.0127 | 0.0290 | 0.0762 | 0.1275 | 0.1093 | 0.1393 | 0.5025 | 11 | 13 | 15 | 20 | 36 | 70 | 125 | 189 | 272 | 0.0574 | 15.56 | 4.832 | 0.5328 | 25517.2 | 9400000 | 4360000000 | 2400000000000 | 0.4719 | 0.1702 | 0.0761 | 0.0028 | 0.2702 | 0.0198 | 0.3311 | 0.1800 | 0.1322 | 0.2075 | 0.0992 | 0.2192 | 0.0530 | 0.1607 | 0.0236 | 0.0959 | 0.0105 | 0.0697 | 0.0042 | 0.0445 | 0.0001 | 0.0000 | 0.0007 | 0.0004 | 0.0009 | 0.0012 | 0.0101 | 0.0086 | 0.0551 | 0.0465 | 0.1067 | 0.0874 | 0.0756 | 0.0609 | 0.1039 | 0.0939 | 0.6470 | 0.7011 | 0.0004 | 0.0005 | 0.0005 | 0.0019 | 0.0037 | 0.0034 | 0.0152 | 0.0180 | 0.0736 | 0.0826 | 0.1416 | 0.1590 | 0.0968 | 0.1084 | 0.1346 | 0.1429 | 0.5337 | 0.4833 | 0.0006 | 0.0003 | 0.0023 | 0.0133 | 0.0603 | 0.1279 | 0.0841 | 0.1215 | 0.5898 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 872 | 892 | | 3689 | 8762 | 488.5 | 108.21 | 84.63 | 135.98 | 344 | 390 | 427 | 458 | 489 | 518 | 545 | 576 | 623 | 0.0781 | 684 | 1.133 | 118.56 | 47.04 | 1 | 0.0848 | 313 | 0.0006 | 83.19 | 7.600 | 0.1213 | 250362.0 | 134000000 | 74800000000 | 43400000000000 | 0.4340 | 0.2055 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0003 | 0.0153 | 0.0026 | 0.0610 | 0.0249 | 0.1194 | 0.0435 | 0.1225 | 0.0384 | 0.1500 | 0.0501 | 0.5305 | 0.8402 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0003 | 0.0075 | 0.0017 | 0.0282 | 0.0215 | 0.0411 | 0.0345 | 0.0380 | 0.0246 | 0.0598 | 0.0328 | 0.8247 | 0.8846 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0231 | 0.0000 | 0.0738 | 0.0000 | 0.1323 | 0.0000 | 0.1877 | 0.0000 | 0.1092 | 0.0000 | 0.1154 | 0.0000 | 0.3569 | 0.0000 | 0.0000 | 0.0011 | 0.0032 | 0.0151 | 0.0572 | 0.1068 | 0.0766 | 0.1176 | 0.6224 | 14 | 16 | 19 | 24 | 34 | 51 | 71 | 100 | 208 | 0.0576 | 11.33 | 4.133 | 0.6484 | 25648.9 | 14400000 | 10400000000 | 8570000000000 | 0.5629 | 0.1030 | 0.0175 | 0.0040 | 0.0903 | 0.0070 | 0.1233 | 0.0663 | 0.1155 | 0.0713 | 0.1291 | 0.1216 | 0.1107 | 0.1266 | 0.1097 | 0.1077 | 0.1175 | 0.1171 | 0.1864 | 0.3784 | 0.0014 | 0.0017 | 0.0025 | 0.0028 | 0.0076 | 0.0083 | 0.0245 | 0.0185 | 0.0736 | 0.0578 | 0.0848 | 0.0797 | 0.0704 | 0.0606 | 0.1050 | 0.0857 | 0.6301 | 0.6850 | 0.0011 | 0.0007 | 0.0011 | 0.0027 | 0.0080 | 0.0066 | 0.0218 | 0.0199 | 0.0856 | 0.0922 | 0.1287 | 0.1293 | 0.0666 | 0.0663 | 0.1034 | 0.1015 | 0.5836 | 0.5809 | 0.0042 | 0.0056 | 0.0075 | 0.0258 | 0.0714 | 0.1104 | 0.0770 | 0.0968 | 0.6012 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1011 | 503 | | 8099 | 27715 | 207.4 | 49.29 | 90.32 | 133.45 | 151 | 164 | 175 | 187 | 199 | 212 | 228 | 248 | 276 | 0.0437 | 1212 | 1.109 | 152.01 | 45.19 | 2 | 0.0436 | 353 | 0.0011 | 36.08 | 7.089 | 0.1990 | 45423.4 | 10500000 | 2560000000 | 657000000000 | 0.4089 | 0.2364 | 0.0004 | 0.0000 | 0.0023 | 0.0001 | 0.0071 | 0.0004 | 0.0235 | 0.0021 | 0.0760 | 0.0188 | 0.1336 | 0.0422 | 0.1525 | 0.0391 | 0.1806 | 0.0611 | 0.4239 | 0.8362 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0001 | 0.0108 | 0.0006 | 0.0290 | 0.0107 | 0.0546 | 0.0216 | 0.0625 | 0.0137 | 0.0784 | 0.0235 | 0.7599 | 0.9297 | 0.0031 | 0.0101 | 0.0081 | 0.0067 | 0.0219 | 0.0236 | 0.0663 | 0.0809 | 0.1006 | 0.1720 | 0.1644 | 0.1585 | 0.1294 | 0.1282 | 0.1413 | 0.1619 | 0.3650 | 0.2580 | 0.0019 | 0.0022 | 0.0111 | 0.0259 | 0.0674 | 0.1078 | 0.1033 | 0.1236 | 0.5567 | 7 | 8 | 10 | 11 | 15 | 35 | 93 | 181 | 284 | 0.1964 | 12.37 | 4.050 | 0.6366 | 25966.7 | 10500000 | 5130000000 | 2920000000000 | 0.4760 | 0.1582 | 0.0839 | 0.0025 | 0.2737 | 0.0194 | 0.3606 | 0.1699 | 0.1380 | 0.2452 | 0.0745 | 0.2308 | 0.0467 | 0.1602 | 0.0182 | 0.0849 | 0.0044 | 0.0541 | 0.0000 | 0.0330 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0003 | 0.0003 | 0.0065 | 0.0072 | 0.0442 | 0.0379 | 0.0776 | 0.0649 | 0.0515 | 0.0468 | 0.0806 | 0.0673 | 0.7388 | 0.7756 | 0.0000 | 0.0001 | 0.0003 | 0.0006 | 0.0004 | 0.0007 | 0.0094 | 0.0113 | 0.0554 | 0.0601 | 0.1006 | 0.1144 | 0.0720 | 0.0756 | 0.1022 | 0.1029 | 0.6597 | 0.6343 | 0.0001 | 0.0000 | 0.0006 | 0.0064 | 0.0501 | 0.0888 | 0.0621 | 0.0936 | 0.6982 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1111 | 520 | | 5855 | 6285 | 143.7 | 37.71 | 129.84 | 96.11 | 100 | 111 | 121 | 130 | 139 | 148 | 159 | 173 | 193 | 0.1158 | 728 | 1.106 | 84.72 | 30.89 | 1 | 0.0386 | 226 | 0.0018 | 22.88 | 6.593 | 0.2522 | 22082.0 | 3630000 | 639000000 | 120000000000 | 0.4079 | 0.2384 | 0.0012 | 0.0000 | 0.0012 | 0.0000 | 0.0053 | 0.0009 | 0.0273 | 0.0032 | 0.0825 | 0.0265 | 0.1384 | 0.0467 | 0.1437 | 0.0495 | 0.1713 | 0.0767 | 0.4291 | 0.7964 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0023 | 0.0007 | 0.0111 | 0.0024 | 0.0330 | 0.0159 | 0.0489 | 0.0238 | 0.0561 | 0.0196 | 0.0820 | 0.0283 | 0.7655 | 0.9092 | 0.0051 | 0.0118 | 0.0093 | 0.0212 | 0.0144 | 0.0259 | 0.0433 | 0.1108 | 0.1155 | 0.1769 | 0.1606 | 0.1792 | 0.1189 | 0.1321 | 0.1589 | 0.1179 | 0.3738 | 0.2241 | 0.0000 | 0.0026 | 0.0098 | 0.0298 | 0.0706 | 0.1009 | 0.1024 | 0.1220 | 0.5618 | 32 | 50 | 66 | 81 | 103 | 128 | 163 | 209 | 265 | 0.0036 | 23.50 | 6.280 | 0.3297 | 26095.3 | 6930000 | 2240000000 | 849000000000 | 0.5029 | 0.1525 | 0.0154 | 0.0026 | 0.0867 | 0.0100 | 0.1762 | 0.0374 | 0.1734 | 0.0756 | 0.1861 | 0.1538 | 0.1463 | 0.2112 | 0.0976 | 0.1556 | 0.0623 | 0.1460 | 0.0560 | 0.2077 | 0.0013 | 0.0013 | 0.0035 | 0.0021 | 0.0061 | 0.0080 | 0.0218 | 0.0157 | 0.0609 | 0.0519 | 0.0984 | 0.0855 | 0.0853 | 0.0703 | 0.1093 | 0.0883 | 0.6133 | 0.6770 | 0.0010 | 0.0013 | 0.0030 | 0.0088 | 0.0075 | 0.0157 | 0.0293 | 0.0452 | 0.0974 | 0.1129 | 0.1546 | 0.1763 | 0.1133 | 0.1129 | 0.1362 | 0.1412 | 0.4578 | 0.3858 | 0.0004 | 0.0036 | 0.0101 | 0.0222 | 0.0677 | 0.1431 | 0.0879 | 0.1278 | 0.5371 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 430 | | 9439 | 30387 | 187.6 | 49.18 | 85.43 | 137.20 | 127 | 150 | 163 | 176 | 187 | 199 | 211 | 226 | 249 | 0.0448 | 1360 | 0.978 | 133.06 | 44.05 | 3 | 0.0366 | 345 | 0.0011 | 36.27 | 7.174 | 0.1963 | 37625.0 | 7970000 | 1770000000 | 413000000000 | 0.4260 | 0.2189 | 0.0002 | 0.0000 | 0.0009 | 0.0001 | 0.0043 | 0.0007 | 0.0199 | 0.0027 | 0.0634 | 0.0169 | 0.1233 | 0.0399 | 0.1423 | 0.0401 | 0.1734 | 0.0580 | 0.4723 | 0.8415 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0072 | 0.0010 | 0.0225 | 0.0102 | 0.0434 | 0.0235 | 0.0516 | 0.0149 | 0.0628 | 0.0250 | 0.8102 | 0.9254 | 0.0063 | 0.0066 | 0.0083 | 0.0115 | 0.0276 | 0.0508 | 0.0683 | 0.0869 | 0.1017 | 0.1328 | 0.1424 | 0.1410 | 0.1226 | 0.1016 | 0.1346 | 0.1279 | 0.3881 | 0.3410 | 0.0009 | 0.0032 | 0.0071 | 0.0234 | 0.0626 | 0.0939 | 0.0934 | 0.1316 | 0.5841 | 10 | 12 | 14 | 16 | 20 | 29 | 62 | 140 | 267 | 0.1579 | 16.30 | 3.924 | 0.6407 | 26120.0 | 12600000 | 7750000000 | 5660000000000 | 0.5727 | 0.1271 | 0.1171 | 0.0076 | 0.2705 | 0.0420 | 0.2342 | 0.2186 | 0.1164 | 0.1757 | 0.1023 | 0.1567 | 0.0686 | 0.1384 | 0.0444 | 0.0856 | 0.0316 | 0.0752 | 0.0148 | 0.1002 | 0.0003 | 0.0005 | 0.0015 | 0.0008 | 0.0032 | 0.0031 | 0.0147 | 0.0133 | 0.0655 | 0.0528 | 0.0960 | 0.0906 | 0.0648 | 0.0549 | 0.0997 | 0.0876 | 0.6543 | 0.6964 | 0.0001 | 0.0004 | 0.0007 | 0.0004 | 0.0029 | 0.0039 | 0.0241 | 0.0258 | 0.0759 | 0.0823 | 0.1193 | 0.1295 | 0.0787 | 0.0827 | 0.1092 | 0.1138 | 0.5892 | 0.5612 | 0.0004 | 0.0010 | 0.0023 | 0.0194 | 0.0694 | 0.1084 | 0.0725 | 0.1053 | 0.6214 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 414 | 325 | | 5437 | 7882 | 437.9 | 83.20 | 101.98 | 125.88 | 341 | 366 | 387 | 407 | 426 | 445 | 470 | 508 | 561 | 0.1009 | 795 | 1.215 | 56.61 | 22.20 | 1 | 0.0270 | 147 | 0.0013 | 34.95 | 6.913 | 0.2030 | 198637.0 | 93400000 | 45500000000 | 22900000000000 | 0.4444 | 0.2029 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0008 | 0.0000 | 0.0120 | 0.0013 | 0.0499 | 0.0139 | 0.1259 | 0.0375 | 0.1288 | 0.0278 | 0.1661 | 0.0447 | 0.5165 | 0.8745 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0047 | 0.0004 | 0.0231 | 0.0107 | 0.0658 | 0.0258 | 0.0594 | 0.0103 | 0.0912 | 0.0214 | 0.7556 | 0.9315 | 0.0000 | 0.0057 | 0.0056 | 0.0230 | 0.0169 | 0.1092 | 0.0666 | 0.1782 | 0.1332 | 0.1494 | 0.1603 | 0.1839 | 0.0971 | 0.1149 | 0.1332 | 0.0977 | 0.3871 | 0.1379 | 0.0013 | 0.0051 | 0.0161 | 0.0442 | 0.0794 | 0.1219 | 0.0968 | 0.1125 | 0.5227 | 6 | 8 | 10 | 15 | 37 | 76 | 132 | 208 | 298 | 0.0817 | 10.67 | 4.715 | 0.5608 | 26243.7 | 8800000 | 3420000000 | 1480000000000 | 0.4564 | 0.1723 | 0.0249 | 0.0017 | 0.0817 | 0.0059 | 0.2664 | 0.0462 | 0.2433 | 0.0891 | 0.1456 | 0.1756 | 0.1155 | 0.2311 | 0.0639 | 0.1395 | 0.0373 | 0.1218 | 0.0213 | 0.1891 | 0.0007 | 0.0003 | 0.0007 | 0.0006 | 0.0029 | 0.0015 | 0.0098 | 0.0052 | 0.0334 | 0.0268 | 0.0579 | 0.0534 | 0.0435 | 0.0365 | 0.0648 | 0.0589 | 0.7863 | 0.8169 | 0.0008 | 0.0000 | 0.0000 | 0.0004 | 0.0016 | 0.0009 | 0.0148 | 0.0152 | 0.0409 | 0.0567 | 0.0678 | 0.0844 | 0.0650 | 0.0612 | 0.0770 | 0.0933 | 0.7319 | 0.6878 | 0.0004 | 0.0015 | 0.0025 | 0.0105 | 0.0384 | 0.0613 | 0.0537 | 0.0758 | 0.7560 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 329 | 607 | | 5771 | 20630 | 529.1 | 107.50 | 83.24 | 139.38 | 401 | 436 | 465 | 492 | 519 | 544 | 572 | 613 | 676 | 0.0490 | 1011 | 1.201 | 99.91 | 40.71 | 1 | 0.0452 | 261 | 0.0007 | 73.75 | 7.558 | 0.1339 | 291461.0 | 167000000 | 99900000000 | 62100000000000 | 0.4158 | 0.2294 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0031 | 0.0002 | 0.0148 | 0.0011 | 0.0604 | 0.0173 | 0.1177 | 0.0353 | 0.1405 | 0.0308 | 0.1599 | 0.0466 | 0.5026 | 0.8687 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0062 | 0.0000 | 0.0291 | 0.0118 | 0.0586 | 0.0242 | 0.0637 | 0.0139 | 0.0850 | 0.0235 | 0.7556 | 0.9266 | 0.0032 | 0.0079 | 0.0149 | 0.0277 | 0.0223 | 0.0316 | 0.0617 | 0.1067 | 0.1415 | 0.1225 | 0.1553 | 0.1858 | 0.0904 | 0.1225 | 0.1170 | 0.1304 | 0.3936 | 0.2648 | 0.0011 | 0.0023 | 0.0076 | 0.0345 | 0.0913 | 0.1330 | 0.1080 | 0.1258 | 0.4966 | 8 | 10 | 11 | 13 | 15 | 21 | 52 | 137 | 282 | 0.0906 | 17.39 | 4.254 | 0.5950 | 26353.8 | 12200000 | 6910000000 | 4480000000000 | 0.6077 | 0.0930 | 0.1055 | 0.0041 | 0.2829 | 0.0287 | 0.3598 | 0.1851 | 0.1526 | 0.2168 | 0.0596 | 0.2162 | 0.0335 | 0.1599 | 0.0037 | 0.0949 | 0.0025 | 0.0609 | 0.0000 | 0.0334 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0019 | 0.0016 | 0.0087 | 0.0077 | 0.0523 | 0.0454 | 0.0796 | 0.0732 | 0.0596 | 0.0497 | 0.0965 | 0.0851 | 0.7010 | 0.7371 | 0.0006 | 0.0002 | 0.0008 | 0.0018 | 0.0020 | 0.0042 | 0.0140 | 0.0178 | 0.0566 | 0.0567 | 0.1052 | 0.1144 | 0.0708 | 0.0696 | 0.1036 | 0.1054 | 0.6462 | 0.6299 | 0.0002 | 0.0004 | 0.0019 | 0.0113 | 0.0550 | 0.0902 | 0.0700 | 0.1005 | 0.6706 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 655 | 519 | | 12431 | 24620 | 390.0 | 70.08 | 73.02 | 145.52 | 287 | 322 | 350 | 376 | 398 | 418 | 437 | 454 | 476 | 0.0531 | 1307 | 0.717 | 116.71 | 35.11 | 3 | 0.0323 | 401 | 0.0014 | 13.24 | 6.814 | 0.3028 | 157023.0 | 65000000 | 27500000000 | 11900000000000 | 0.4378 | 0.1981 | 0.0007 | 0.0000 | 0.0029 | 0.0000 | 0.0055 | 0.0000 | 0.0115 | 0.0009 | 0.0276 | 0.0098 | 0.0447 | 0.0175 | 0.0492 | 0.0111 | 0.0732 | 0.0171 | 0.7847 | 0.9436 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0000 | 0.0037 | 0.0009 | 0.0122 | 0.0098 | 0.0195 | 0.0175 | 0.0178 | 0.0105 | 0.0271 | 0.0152 | 0.9168 | 0.9461 | 0.0102 | 1.0000 | 0.0215 | 0.0000 | 0.0269 | 0.0000 | 0.0449 | 0.0000 | 0.0682 | 0.0000 | 0.0922 | 0.0000 | 0.0999 | 0.0000 | 0.1191 | 0.0000 | 0.5171 | 0.0000 | 0.0007 | 0.0036 | 0.0042 | 0.0104 | 0.0227 | 0.0348 | 0.0407 | 0.0547 | 0.8282 | 8 | 10 | 11 | 13 | 15 | 20 | 33 | 82 | 218 | 0.1379 | 2.58 | 2.741 | 0.6004 | 26508.4 | 16200000 | 12600000000 | 11400000000000 | 0.6289 | 0.0769 | 0.0413 | 0.0027 | 0.1013 | 0.0182 | 0.1888 | 0.0633 | 0.1750 | 0.0919 | 0.1721 | 0.1461 | 0.1327 | 0.1875 | 0.1013 | 0.1379 | 0.0560 | 0.1347 | 0.0315 | 0.2176 | 0.0002 | 0.0005 | 0.0007 | 0.0006 | 0.0016 | 0.0015 | 0.0123 | 0.0101 | 0.0446 | 0.0428 | 0.0768 | 0.0683 | 0.0519 | 0.0466 | 0.0718 | 0.0703 | 0.7402 | 0.7592 | 0.0004 | 0.0009 | 0.0008 | 0.0018 | 0.0023 | 0.0018 | 0.0159 | 0.0140 | 0.0529 | 0.0605 | 0.0898 | 0.0918 | 0.0567 | 0.0628 | 0.0814 | 0.0868 | 0.6997 | 0.6794 | 0.0004 | 0.0000 | 0.0015 | 0.0114 | 0.0529 | 0.0806 | 0.0550 | 0.0825 | 0.7157 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1208 | 205 | | 6928 | 22071 | 341.7 | 78.65 | 108.42 | 121.55 | 242 | 273 | 297 | 318 | 338 | 358 | 381 | 406 | 444 | 0.0464 | 1025 | 0.821 | 127.02 | 32.56 | 1 | 0.0485 | 336 | 0.0010 | 44.29 | 7.174 | 0.1864 | 122938.0 | 46400000 | 18300000000 | 7530000000000 | 0.4442 | 0.2150 | 0.0005 | 0.0000 | 0.0009 | 0.0002 | 0.0054 | 0.0000 | 0.0289 | 0.0006 | 0.0774 | 0.0196 | 0.1548 | 0.0468 | 0.1496 | 0.0486 | 0.1733 | 0.0699 | 0.4092 | 0.8144 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0007 | 0.0000 | 0.0054 | 0.0001 | 0.0331 | 0.0134 | 0.0668 | 0.0319 | 0.0580 | 0.0246 | 0.0875 | 0.0358 | 0.7479 | 0.8940 | 0.0023 | 0.0124 | 0.0062 | 0.0155 | 0.0247 | 0.0310 | 0.0918 | 0.1455 | 0.1550 | 0.2012 | 0.1958 | 0.1827 | 0.1210 | 0.1022 | 0.1365 | 0.1269 | 0.2668 | 0.1827 | 0.0003 | 0.0015 | 0.0063 | 0.0271 | 0.0855 | 0.1353 | 0.1139 | 0.1317 | 0.4984 | 9 | 13 | 22 | 40 | 63 | 94 | 133 | 188 | 275 | 0.0306 | 13.52 | 5.344 | 0.4677 | 26526.8 | 9310000 | 4040000000 | 2020000000000 | 0.4133 | 0.2398 | 0.0339 | 0.0012 | 0.1396 | 0.0060 | 0.2401 | 0.0523 | 0.1953 | 0.1264 | 0.1400 | 0.1867 | 0.1291 | 0.2003 | 0.0747 | 0.1544 | 0.0331 | 0.1250 | 0.0141 | 0.1478 | 0.0006 | 0.0003 | 0.0014 | 0.0015 | 0.0028 | 0.0033 | 0.0161 | 0.0120 | 0.0537 | 0.0500 | 0.0941 | 0.0727 | 0.0729 | 0.0606 | 0.1043 | 0.0889 | 0.6540 | 0.7107 | 0.0007 | 0.0010 | 0.0031 | 0.0019 | 0.0047 | 0.0087 | 0.0232 | 0.0267 | 0.0849 | 0.0952 | 0.1181 | 0.1316 | 0.0860 | 0.0864 | 0.1223 | 0.1332 | 0.5570 | 0.5153 | 0.0002 | 0.0019 | 0.0039 | 0.0193 | 0.0666 | 0.1098 | 0.0796 | 0.1117 | 0.6070 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1069 | 181 | | 1596 | 20629 | 124.5 | 28.67 | 72.87 | 146.49 | 98 | 102 | 107 | 111 | 116 | 122 | 130 | 143 | 162 | 0.0438 | 904 | 0.809 | 207.96 | 60.42 | 1 | 0.3440 | 549 | 0.0093 | 6.72 | 5.134 | 0.4357 | 16321.0 | 2270000 | 339000000 | 54100000000 | 0.4382 | 0.2050 | 0.0064 | 0.0000 | 0.0064 | 0.0000 | 0.0091 | 0.0000 | 0.0246 | 0.0027 | 0.0665 | 0.0317 | 0.0938 | 0.0661 | 0.1084 | 0.0465 | 0.1321 | 0.0715 | 0.5528 | 0.7815 | 0.0051 | 0.0000 | 0.0044 | 0.0000 | 0.0066 | 0.0000 | 0.0139 | 0.0025 | 0.0285 | 0.0257 | 0.0446 | 0.0426 | 0.0599 | 0.0238 | 0.0833 | 0.0401 | 0.7538 | 0.8653 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0111 | 0.0000 | 0.0406 | 0.0000 | 0.1144 | 0.0000 | 0.1476 | 0.0000 | 0.1144 | 0.0000 | 0.1255 | 0.0000 | 0.4428 | 0.0000 | 0.0016 | 0.0081 | 0.0049 | 0.0357 | 0.0535 | 0.1086 | 0.0729 | 0.1135 | 0.6013 | 7 | 9 | 11 | 12 | 13 | 15 | 19 | 61 | 281 | 0.2995 | 21.07 | 3.063 | 0.7088 | 26767.6 | 14200000 | 8950000000 | 6390000000000 | 0.3754 | 0.2426 | 0.1380 | 0.0048 | 0.3646 | 0.0530 | 0.2760 | 0.2133 | 0.1250 | 0.2337 | 0.0781 | 0.2422 | 0.0156 | 0.1627 | 0.0026 | 0.0590 | 0.0000 | 0.0217 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0005 | 0.0062 | 0.0050 | 0.0345 | 0.0311 | 0.0536 | 0.0493 | 0.0409 | 0.0369 | 0.0551 | 0.0516 | 0.8092 | 0.8256 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0018 | 0.0030 | 0.0082 | 0.0075 | 0.0356 | 0.0413 | 0.0757 | 0.0865 | 0.0522 | 0.0543 | 0.0707 | 0.0848 | 0.7559 | 0.7221 | 0.0000 | 0.0003 | 0.0008 | 0.0058 | 0.0340 | 0.0678 | 0.0421 | 0.0646 | 0.7846 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 981 | 384 | | 5976 | 15063 | 375.2 | 139.04 | 87.22 | 138.43 | 122 | 252 | 332 | 379 | 411 | 436 | 459 | 488 | 529 | 0.0690 | 1040 | 1.006 | 89.27 | 27.02 | 6 | 0.0370 | 221 | 0.0008 | 30.99 | 7.402 | 0.2347 | 160087.0 | 72700000 | 34300000000 | 16600000000000 | 0.3898 | 0.2387 | 0.0000 | 0.0007 | 0.0017 | 0.0002 | 0.0067 | 0.0009 | 0.0168 | 0.0037 | 0.0750 | 0.0273 | 0.1215 | 0.0375 | 0.1056 | 0.0371 | 0.1567 | 0.0526 | 0.5159 | 0.8400 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0010 | 0.0162 | 0.0143 | 0.0270 | 0.0202 | 0.0191 | 0.0149 | 0.0299 | 0.0212 | 0.9067 | 0.9283 | 0.0010 | 0.0079 | 0.0044 | 0.0111 | 0.0092 | 0.0142 | 0.0247 | 0.0190 | 0.0499 | 0.0774 | 0.0727 | 0.0900 | 0.0751 | 0.0979 | 0.0931 | 0.1327 | 0.6699 | 0.5498 | 0.0000 | 0.0000 | 0.0003 | 0.0047 | 0.0261 | 0.0387 | 0.0368 | 0.0506 | 0.8428 | 6 | 9 | 12 | 16 | 25 | 42 | 68 | 128 | 272 | 0.0676 | 12.92 | 4.513 | 0.5910 | 26768.0 | 12200000 | 6560000000 | 3860000000000 | 0.6432 | 0.1082 | 0.0291 | 0.0037 | 0.1315 | 0.0140 | 0.2008 | 0.0494 | 0.1526 | 0.1090 | 0.1345 | 0.1747 | 0.1305 | 0.1850 | 0.0723 | 0.1072 | 0.0773 | 0.1235 | 0.0713 | 0.2335 | 0.0004 | 0.0011 | 0.0020 | 0.0030 | 0.0027 | 0.0032 | 0.0162 | 0.0112 | 0.0605 | 0.0539 | 0.0900 | 0.0723 | 0.0693 | 0.0632 | 0.0924 | 0.0883 | 0.6664 | 0.7038 | 0.0017 | 0.0010 | 0.0017 | 0.0041 | 0.0049 | 0.0073 | 0.0171 | 0.0188 | 0.0713 | 0.0786 | 0.0991 | 0.0958 | 0.0739 | 0.0856 | 0.1026 | 0.1117 | 0.6275 | 0.5969 | 0.0016 | 0.0028 | 0.0041 | 0.0173 | 0.0693 | 0.0929 | 0.0745 | 0.0962 | 0.6412 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 954 | 880 | | 1679 | 5441 | 653.6 | 119.11 | 75.62 | 146.47 | 478 | 542 | 591 | 627 | 661 | 696 | 731 | 766 | 800 | 0.0884 | 481 | 0.755 | 132.23 | 36.35 | 1 | 0.2287 | 384 | 0.0009 | 82.04 | 7.094 | 0.1478 | 441315.0 | 307000000 | 218000000000 | 159000000000000 | 0.3946 | 0.2342 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0086 | 0.0018 | 0.0522 | 0.0283 | 0.0779 | 0.0361 | 0.0693 | 0.0307 | 0.1259 | 0.0451 | 0.6652 | 0.8581 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0018 | 0.0313 | 0.0281 | 0.0392 | 0.0329 | 0.0271 | 0.0257 | 0.0499 | 0.0418 | 0.8504 | 0.8698 | 0.0042 | 0.0000 | 0.0169 | 0.0000 | 0.0254 | 0.0000 | 0.0424 | 0.0000 | 0.0890 | 0.0000 | 0.1271 | 0.0000 | 0.1144 | 0.0000 | 0.1271 | 0.0000 | 0.4534 | 0.0000 | 0.0011 | 0.0011 | 0.0034 | 0.0103 | 0.0525 | 0.0627 | 0.0490 | 0.0855 | 0.7343 | 7 | 9 | 11 | 13 | 17 | 28 | 60 | 104 | 173 | 0.0733 | 1.76 | 2.761 | 0.5531 | 27168.4 | 17800000 | 14800000000 | 13800000000000 | 0.4065 | 0.2202 | 0.0128 | 0.0026 | 0.0204 | 0.0102 | 0.0510 | 0.0269 | 0.1301 | 0.0409 | 0.1913 | 0.0882 | 0.2041 | 0.1317 | 0.1735 | 0.1228 | 0.1301 | 0.2008 | 0.0867 | 0.3760 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0018 | 0.0027 | 0.0092 | 0.0070 | 0.0308 | 0.0271 | 0.0450 | 0.0411 | 0.0431 | 0.0319 | 0.0603 | 0.0541 | 0.8097 | 0.8343 | 0.0008 | 0.0009 | 0.0000 | 0.0019 | 0.0049 | 0.0075 | 0.0130 | 0.0160 | 0.0381 | 0.0479 | 0.0657 | 0.0695 | 0.0536 | 0.0638 | 0.0869 | 0.0892 | 0.7370 | 0.7033 | 0.0000 | 0.0063 | 0.0042 | 0.0105 | 0.0359 | 0.0450 | 0.0549 | 0.0703 | 0.7729 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1028 | 231 | | 11368 | 9358 | 393.3 | 133.58 | 93.30 | 136.68 | 187 | 274 | 336 | 383 | 422 | 451 | 481 | 509 | 544 | 0.1038 | 971 | 0.530 | 101.02 | 17.03 | 7 | 0.0223 | 254 | 0.0009 | 24.62 | 7.358 | 0.2464 | 172513.0 | 80400000 | 39000000000 | 19500000000000 | 0.5210 | 0.1387 | 0.0011 | 0.0006 | 0.0017 | 0.0005 | 0.0047 | 0.0018 | 0.0170 | 0.0049 | 0.0766 | 0.0277 | 0.1275 | 0.0545 | 0.1031 | 0.0384 | 0.1389 | 0.0594 | 0.5294 | 0.8122 | 0.0000 | 0.0001 | 0.0001 | 0.0001 | 0.0000 | 0.0002 | 0.0023 | 0.0012 | 0.0230 | 0.0184 | 0.0392 | 0.0346 | 0.0241 | 0.0188 | 0.0387 | 0.0285 | 0.8726 | 0.8980 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0061 | 0.0000 | 0.0163 | 0.0000 | 0.0472 | 0.0000 | 0.0674 | 0.0000 | 0.0653 | 0.0000 | 0.0888 | 0.0000 | 0.7054 | 1.0000 | 0.0003 | 0.0002 | 0.0009 | 0.0047 | 0.0314 | 0.0487 | 0.0382 | 0.0542 | 0.8214 | 10 | 12 | 15 | 20 | 34 | 52 | 79 | 150 | 276 | 0.1156 | 10.49 | 4.045 | 0.6216 | 27384.8 | 12500000 | 7130000000 | 4620000000000 | 0.4672 | 0.1594 | 0.0875 | 0.0139 | 0.2611 | 0.0541 | 0.2439 | 0.2073 | 0.1148 | 0.1314 | 0.0933 | 0.1294 | 0.0689 | 0.1208 | 0.0473 | 0.0812 | 0.0445 | 0.0759 | 0.0387 | 0.1861 | 0.0003 | 0.0020 | 0.0031 | 0.0022 | 0.0037 | 0.0053 | 0.0252 | 0.0193 | 0.0857 | 0.0735 | 0.1244 | 0.1092 | 0.0857 | 0.0732 | 0.1163 | 0.1151 | 0.5556 | 0.6003 | 0.0000 | 0.0000 | 0.0004 | 0.0010 | 0.0045 | 0.0077 | 0.0254 | 0.0305 | 0.0994 | 0.1056 | 0.1582 | 0.1608 | 0.0856 | 0.0944 | 0.1270 | 0.1370 | 0.4996 | 0.4630 | 0.0008 | 0.0044 | 0.0044 | 0.0252 | 0.0913 | 0.1442 | 0.0873 | 0.1197 | 0.5226 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 620 | 230 | | 4285 | 3286 | 144.3 | 36.47 | 138.38 | 91.26 | 103 | 114 | 122 | 130 | 138 | 148 | 158 | 173 | 194 | 0.1869 | 614 | 1.042 | 86.49 | 33.29 | 1 | 0.0567 | 243 | 0.0019 | 26.80 | 6.577 | 0.2264 | 22156.9 | 3620000 | 632000000 | 117000000000 | 0.4068 | 0.2461 | 0.0008 | 0.0000 | 0.0024 | 0.0000 | 0.0068 | 0.0008 | 0.0409 | 0.0036 | 0.0895 | 0.0250 | 0.1604 | 0.0595 | 0.1805 | 0.0680 | 0.1781 | 0.0883 | 0.3406 | 0.7550 | 0.0003 | 0.0000 | 0.0015 | 0.0000 | 0.0033 | 0.0007 | 0.0152 | 0.0019 | 0.0396 | 0.0150 | 0.0677 | 0.0307 | 0.0793 | 0.0309 | 0.0999 | 0.0421 | 0.6933 | 0.8786 | 0.0023 | 0.0063 | 0.0058 | 0.0284 | 0.0232 | 0.0473 | 0.0719 | 0.1356 | 0.1241 | 0.1703 | 0.1694 | 0.2177 | 0.1230 | 0.1041 | 0.1381 | 0.1104 | 0.3422 | 0.1798 | 0.0011 | 0.0074 | 0.0079 | 0.0370 | 0.0894 | 0.1174 | 0.1259 | 0.1364 | 0.4775 | 49 | 67 | 82 | 100 | 117 | 136 | 159 | 195 | 252 | 0.0034 | 28.02 | 6.143 | 0.3124 | 27476.4 | 7420000 | 2560000000 | 1060000000000 | 0.5807 | 0.0980 | 0.0129 | 0.0006 | 0.0526 | 0.0104 | 0.1671 | 0.0245 | 0.1542 | 0.0736 | 0.1916 | 0.1373 | 0.1729 | 0.1674 | 0.1320 | 0.1582 | 0.0713 | 0.1398 | 0.0456 | 0.2882 | 0.0006 | 0.0000 | 0.0034 | 0.0030 | 0.0130 | 0.0039 | 0.0419 | 0.0226 | 0.1058 | 0.0826 | 0.1533 | 0.1274 | 0.1250 | 0.1044 | 0.1408 | 0.1261 | 0.4163 | 0.5298 | 0.0066 | 0.0075 | 0.0055 | 0.0105 | 0.0362 | 0.0359 | 0.0768 | 0.0734 | 0.1480 | 0.1722 | 0.1612 | 0.1722 | 0.1261 | 0.1257 | 0.1469 | 0.1437 | 0.2928 | 0.2590 | 0.0023 | 0.0046 | 0.0201 | 0.0610 | 0.1251 | 0.1807 | 0.1127 | 0.1490 | 0.3444 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 289 | 493 | | 6798 | 23833 | 396.9 | 72.62 | 122.22 | 112.72 | 305 | 332 | 353 | 372 | 393 | 413 | 434 | 460 | 496 | 0.0457 | 1090 | 1.062 | 97.45 | 34.93 | 1 | 0.0374 | 254 | 0.0017 | 19.12 | 6.637 | 0.2476 | 162807.0 | 68900000 | 30000000000 | 13500000000000 | 0.3895 | 0.2520 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0023 | 0.0005 | 0.0107 | 0.0006 | 0.0469 | 0.0131 | 0.0916 | 0.0269 | 0.1033 | 0.0220 | 0.1432 | 0.0346 | 0.6015 | 0.9022 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0009 | 0.0003 | 0.0043 | 0.0003 | 0.0197 | 0.0111 | 0.0380 | 0.0209 | 0.0404 | 0.0105 | 0.0584 | 0.0164 | 0.8383 | 0.9404 | 0.0080 | 0.0227 | 0.0130 | 0.0455 | 0.0260 | 0.1136 | 0.0721 | 0.1212 | 0.1321 | 0.2045 | 0.1922 | 0.1515 | 0.1251 | 0.0985 | 0.1512 | 0.1061 | 0.2803 | 0.1364 | 0.0006 | 0.0018 | 0.0076 | 0.0223 | 0.0572 | 0.1036 | 0.0899 | 0.1253 | 0.5917 | 13 | 21 | 38 | 64 | 93 | 125 | 160 | 203 | 274 | 0.0273 | 9.30 | 5.190 | 0.4969 | 27642.2 | 8480000 | 3190000000 | 1400000000000 | 0.4768 | 0.1673 | 0.0272 | 0.0014 | 0.1103 | 0.0069 | 0.2030 | 0.0512 | 0.1793 | 0.1036 | 0.1586 | 0.1664 | 0.1277 | 0.1784 | 0.0836 | 0.1457 | 0.0699 | 0.1463 | 0.0404 | 0.2001 | 0.0004 | 0.0001 | 0.0012 | 0.0008 | 0.0030 | 0.0025 | 0.0136 | 0.0101 | 0.0526 | 0.0452 | 0.0989 | 0.0755 | 0.0730 | 0.0660 | 0.1124 | 0.0959 | 0.6447 | 0.7039 | 0.0012 | 0.0020 | 0.0031 | 0.0065 | 0.0092 | 0.0131 | 0.0290 | 0.0361 | 0.0788 | 0.0934 | 0.1280 | 0.1326 | 0.0965 | 0.1068 | 0.1320 | 0.1384 | 0.5220 | 0.4711 | 0.0005 | 0.0012 | 0.0038 | 0.0208 | 0.0676 | 0.1100 | 0.0939 | 0.1245 | 0.5777 |