High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 406 | 806 | | 3869 | 9909 | 688.7 | 123.70 | 61.45 | 130.52 | 523 | 588 | 635 | 670 | 698 | 722 | 743 | 770 | 857 | 0.0768 | 761 | 1.128 | 89.45 | 33.12 | 2 | 0.0605 | 234 | 0.0009 | 60.15 | 7.294 | 0.1719 | 489556.0 | 358000000 | 269000000000 | 207000000000000 | 0.3551 | 0.2759 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0039 | 0.0005 | 0.0389 | 0.0191 | 0.0470 | 0.0343 | 0.0473 | 0.0252 | 0.0666 | 0.0433 | 0.7950 | 0.8776 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0021 | 0.0005 | 0.0251 | 0.0187 | 0.0338 | 0.0305 | 0.0311 | 0.0174 | 0.0429 | 0.0274 | 0.8639 | 0.9056 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0217 | 0.0000 | 0.0522 | 0.0000 | 0.0435 | 0.0000 | 0.0783 | 0.0000 | 0.0696 | 0.0000 | 0.7348 | 0.0000 | 0.0005 | 0.0014 | 0.0048 | 0.0144 | 0.0393 | 0.0672 | 0.0561 | 0.0859 | 0.7303 | 6 | 8 | 9 | 10 | 11 | 13 | 21 | 63 | 186 | 0.1948 | 6.58 | 2.831 | 0.6506 | 20808.7 | 11500000 | 7940000000 | 6280000000000 | 0.3866 | 0.2159 | 0.0387 | 0.0072 | 0.1613 | 0.0273 | 0.2355 | 0.1164 | 0.2065 | 0.1193 | 0.1839 | 0.1379 | 0.0903 | 0.1897 | 0.0548 | 0.1149 | 0.0194 | 0.1379 | 0.0097 | 0.1494 | 0.0005 | 0.0000 | 0.0005 | 0.0008 | 0.0009 | 0.0004 | 0.0147 | 0.0132 | 0.0372 | 0.0371 | 0.0689 | 0.0556 | 0.0358 | 0.0342 | 0.0611 | 0.0671 | 0.7804 | 0.7917 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0032 | 0.0017 | 0.0118 | 0.0121 | 0.0428 | 0.0537 | 0.0707 | 0.0779 | 0.0386 | 0.0467 | 0.0739 | 0.0848 | 0.7590 | 0.7213 | 0.0005 | 0.0005 | 0.0020 | 0.0125 | 0.0435 | 0.0659 | 0.0390 | 0.0649 | 0.7712 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1003 | 529 | | 2853 | 9441 | 157.4 | 32.63 | 102.01 | 102.33 | 118 | 129 | 138 | 146 | 154 | 163 | 173 | 186 | 203 | 0.0660 | 623 | 0.979 | 160.03 | 54.33 | 2 | 0.1497 | 427 | 0.0019 | 22.36 | 6.477 | 0.2304 | 25843.1 | 4420000 | 785000000 | 145000000000 | 0.4460 | 0.2072 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0192 | 0.0004 | 0.0719 | 0.0167 | 0.1561 | 0.0452 | 0.1556 | 0.0440 | 0.1859 | 0.0766 | 0.4081 | 0.8172 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0079 | 0.0004 | 0.0339 | 0.0128 | 0.0715 | 0.0313 | 0.0619 | 0.0174 | 0.0983 | 0.0366 | 0.7251 | 0.9015 | 0.0058 | 0.0182 | 0.0136 | 0.0636 | 0.0312 | 0.1091 | 0.0546 | 0.1364 | 0.1598 | 0.2091 | 0.1598 | 0.1636 | 0.1326 | 0.1091 | 0.1501 | 0.0727 | 0.2924 | 0.1182 | 0.0022 | 0.0022 | 0.0082 | 0.0461 | 0.0848 | 0.1413 | 0.1048 | 0.1361 | 0.4743 | 11 | 16 | 29 | 45 | 66 | 93 | 129 | 176 | 245 | 0.0152 | 19.08 | 5.619 | 0.4258 | 20875.8 | 5920000 | 2050000000 | 824000000000 | 0.6242 | 0.0881 | 0.0390 | 0.0034 | 0.1453 | 0.0111 | 0.2356 | 0.0610 | 0.1887 | 0.1245 | 0.1532 | 0.1987 | 0.1098 | 0.1906 | 0.0691 | 0.1394 | 0.0452 | 0.1275 | 0.0142 | 0.1437 | 0.0005 | 0.0002 | 0.0017 | 0.0008 | 0.0036 | 0.0041 | 0.0167 | 0.0119 | 0.0708 | 0.0582 | 0.1106 | 0.0877 | 0.0886 | 0.0769 | 0.1254 | 0.1103 | 0.5821 | 0.6499 | 0.0013 | 0.0008 | 0.0027 | 0.0032 | 0.0103 | 0.0122 | 0.0279 | 0.0363 | 0.0920 | 0.1137 | 0.1411 | 0.1512 | 0.1159 | 0.1204 | 0.1388 | 0.1524 | 0.4699 | 0.4098 | 0.0011 | 0.0034 | 0.0062 | 0.0220 | 0.0772 | 0.1297 | 0.1020 | 0.1334 | 0.5249 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1189 | 155 | | 5618 | 13253 | 344.2 | 70.32 | 104.68 | 99.98 | 259 | 282 | 300 | 316 | 333 | 354 | 379 | 407 | 444 | 0.0684 | 907 | 0.910 | 83.20 | 23.02 | 1 | 0.0377 | 212 | 0.0019 | 20.54 | 6.561 | 0.2353 | 123384.0 | 46000000 | 17900000000 | 7180000000000 | 0.3957 | 0.2470 | 0.0003 | 0.0000 | 0.0008 | 0.0002 | 0.0063 | 0.0002 | 0.0181 | 0.0011 | 0.0550 | 0.0161 | 0.1125 | 0.0345 | 0.1341 | 0.0319 | 0.1675 | 0.0521 | 0.5055 | 0.8638 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0032 | 0.0000 | 0.0071 | 0.0002 | 0.0199 | 0.0120 | 0.0402 | 0.0218 | 0.0557 | 0.0130 | 0.0771 | 0.0230 | 0.7960 | 0.9301 | 0.0029 | 0.0140 | 0.0069 | 0.0421 | 0.0255 | 0.0514 | 0.0609 | 0.1495 | 0.1159 | 0.1822 | 0.1906 | 0.1869 | 0.1375 | 0.1122 | 0.1503 | 0.1075 | 0.3094 | 0.1542 | 0.0020 | 0.0024 | 0.0071 | 0.0256 | 0.0643 | 0.1057 | 0.0923 | 0.1179 | 0.5826 | 14 | 27 | 43 | 59 | 75 | 94 | 119 | 159 | 237 | 0.0186 | 8.63 | 5.042 | 0.5074 | 20954.6 | 6170000 | 2290000000 | 982000000000 | 0.4377 | 0.2064 | 0.0105 | 0.0017 | 0.0659 | 0.0063 | 0.1467 | 0.0244 | 0.1714 | 0.0701 | 0.1841 | 0.1287 | 0.1586 | 0.1670 | 0.1270 | 0.1575 | 0.0857 | 0.1608 | 0.0501 | 0.2834 | 0.0010 | 0.0010 | 0.0042 | 0.0013 | 0.0055 | 0.0034 | 0.0205 | 0.0174 | 0.0627 | 0.0477 | 0.0920 | 0.0753 | 0.0818 | 0.0727 | 0.1040 | 0.0953 | 0.6284 | 0.6859 | 0.0011 | 0.0027 | 0.0038 | 0.0036 | 0.0089 | 0.0103 | 0.0277 | 0.0262 | 0.0728 | 0.0839 | 0.1098 | 0.1194 | 0.0899 | 0.0902 | 0.1106 | 0.1154 | 0.5756 | 0.5484 | 0.0011 | 0.0045 | 0.0087 | 0.0268 | 0.0665 | 0.1035 | 0.0854 | 0.1079 | 0.5957 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1093 | 541 | | 6510 | 19083 | 329.3 | 67.71 | 96.25 | 108.79 | 246 | 270 | 288 | 306 | 322 | 340 | 362 | 390 | 424 | 0.0512 | 978 | 1.154 | 97.62 | 37.11 | 1 | 0.0393 | 256 | 0.0013 | 28.44 | 6.892 | 0.2102 | 112993.0 | 40300000 | 14900000000 | 5720000000000 | 0.4415 | 0.2097 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0043 | 0.0003 | 0.0149 | 0.0014 | 0.0652 | 0.0158 | 0.1269 | 0.0341 | 0.1409 | 0.0340 | 0.1777 | 0.0597 | 0.4684 | 0.8547 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0018 | 0.0000 | 0.0065 | 0.0002 | 0.0277 | 0.0116 | 0.0554 | 0.0212 | 0.0606 | 0.0158 | 0.0862 | 0.0306 | 0.7611 | 0.9207 | 0.0042 | 0.0157 | 0.0067 | 0.0000 | 0.0177 | 0.0627 | 0.0725 | 0.1412 | 0.1197 | 0.1961 | 0.1594 | 0.1843 | 0.1197 | 0.1451 | 0.1476 | 0.1451 | 0.3524 | 0.1098 | 0.0013 | 0.0033 | 0.0086 | 0.0309 | 0.0800 | 0.1165 | 0.1009 | 0.1201 | 0.5385 | 7 | 9 | 12 | 27 | 55 | 86 | 127 | 179 | 256 | 0.0642 | 12.35 | 5.075 | 0.5282 | 21099.1 | 6350000 | 2360000000 | 1030000000000 | 0.4788 | 0.1572 | 0.0140 | 0.0020 | 0.0726 | 0.0070 | 0.1767 | 0.0276 | 0.1707 | 0.0700 | 0.1712 | 0.1521 | 0.1612 | 0.1785 | 0.0996 | 0.1459 | 0.0776 | 0.1537 | 0.0566 | 0.2631 | 0.0004 | 0.0001 | 0.0007 | 0.0005 | 0.0036 | 0.0013 | 0.0080 | 0.0073 | 0.0353 | 0.0283 | 0.0641 | 0.0499 | 0.0529 | 0.0434 | 0.0741 | 0.0687 | 0.7611 | 0.8004 | 0.0005 | 0.0002 | 0.0015 | 0.0007 | 0.0028 | 0.0046 | 0.0118 | 0.0137 | 0.0486 | 0.0587 | 0.0819 | 0.0869 | 0.0679 | 0.0845 | 0.1039 | 0.1128 | 0.6810 | 0.6378 | 0.0004 | 0.0006 | 0.0017 | 0.0103 | 0.0404 | 0.0685 | 0.0604 | 0.0855 | 0.7323 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 658 | 779 | | 5169 | 11172 | 137.7 | 32.46 | 113.17 | 91.87 | 100 | 111 | 120 | 127 | 134 | 142 | 150 | 160 | 178 | 0.0719 | 803 | 0.859 | 104.81 | 28.16 | 1 | 0.0530 | 274 | 0.0021 | 21.91 | 6.455 | 0.2447 | 20003.2 | 3080000 | 502000000 | 87100000000 | 0.4380 | 0.2131 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0072 | 0.0000 | 0.0208 | 0.0021 | 0.0760 | 0.0199 | 0.1417 | 0.0475 | 0.1466 | 0.0488 | 0.1981 | 0.0785 | 0.4089 | 0.8031 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0077 | 0.0008 | 0.0363 | 0.0134 | 0.0672 | 0.0294 | 0.0593 | 0.0203 | 0.0997 | 0.0401 | 0.7272 | 0.8959 | 0.0081 | 0.0139 | 0.0185 | 0.0209 | 0.0288 | 0.0453 | 0.0819 | 0.1603 | 0.1453 | 0.1672 | 0.1926 | 0.1812 | 0.1119 | 0.0836 | 0.1407 | 0.1324 | 0.2722 | 0.1951 | 0.0025 | 0.0042 | 0.0148 | 0.0420 | 0.0954 | 0.1238 | 0.1081 | 0.1361 | 0.4731 | 15 | 30 | 49 | 70 | 92 | 118 | 149 | 185 | 238 | 0.0049 | 34.56 | 6.477 | 0.3146 | 21247.0 | 5290000 | 1630000000 | 593000000000 | 0.5230 | 0.1320 | 0.0237 | 0.0013 | 0.1084 | 0.0065 | 0.2323 | 0.0500 | 0.1730 | 0.0940 | 0.1806 | 0.1655 | 0.1412 | 0.2079 | 0.0846 | 0.1542 | 0.0415 | 0.1364 | 0.0146 | 0.1841 | 0.0004 | 0.0003 | 0.0009 | 0.0000 | 0.0057 | 0.0022 | 0.0210 | 0.0114 | 0.0670 | 0.0515 | 0.1169 | 0.0950 | 0.0867 | 0.0772 | 0.1217 | 0.1026 | 0.5799 | 0.6597 | 0.0011 | 0.0007 | 0.0029 | 0.0076 | 0.0111 | 0.0152 | 0.0315 | 0.0444 | 0.0978 | 0.1136 | 0.1574 | 0.1758 | 0.0999 | 0.1242 | 0.1479 | 0.1351 | 0.4505 | 0.3834 | 0.0009 | 0.0021 | 0.0064 | 0.0277 | 0.0813 | 0.1285 | 0.1054 | 0.1321 | 0.5156 | ||
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1046 | 281 | | 697 | 6737 | 49.7 | 11.06 | 107.38 | 98.61 | 35 | 40 | 43 | 46 | 49 | 53 | 56 | 60 | 66 | 0.0687 | 463 | 0.653 | 94.02 | 20.03 | 1 | 0.3989 | 278 | 0.0147 | 2.37 | 4.400 | 0.5020 | 2589.0 | 140960 | 7970000 | 466000000 | 0.3646 | 0.2679 | 0.0024 | 0.0000 | 0.0049 | 0.0000 | 0.0147 | 0.0015 | 0.0293 | 0.0122 | 0.0880 | 0.0518 | 0.1174 | 0.0487 | 0.1418 | 0.0700 | 0.2103 | 0.1035 | 0.3912 | 0.7123 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0179 | 0.0088 | 0.0448 | 0.0423 | 0.0448 | 0.0350 | 0.0538 | 0.0482 | 0.0878 | 0.0496 | 0.7437 | 0.8161 | 0.0000 | 0.0714 | 0.0067 | 0.0714 | 0.0537 | 0.1071 | 0.0604 | 0.2143 | 0.0940 | 0.1429 | 0.0872 | 0.1429 | 0.0940 | 0.2500 | 0.1678 | 0.0000 | 0.4362 | 0.0000 | 0.0000 | 0.0087 | 0.0029 | 0.0320 | 0.0552 | 0.0698 | 0.0756 | 0.1105 | 0.6453 | 16 | 26 | 41 | 57 | 78 | 101 | 132 | 173 | 239 | 0.0142 | 10.47 | 5.299 | 0.4760 | 21253.2 | 5970000 | 2090000000 | 847000000000 | 0.5145 | 0.1485 | 0.0252 | 0.0015 | 0.0572 | 0.0053 | 0.1725 | 0.0393 | 0.1812 | 0.0766 | 0.1764 | 0.1392 | 0.1764 | 0.1702 | 0.1066 | 0.1387 | 0.0640 | 0.1528 | 0.0407 | 0.2764 | 0.0006 | 0.0003 | 0.0013 | 0.0016 | 0.0064 | 0.0045 | 0.0186 | 0.0143 | 0.0578 | 0.0428 | 0.0902 | 0.0659 | 0.0876 | 0.0653 | 0.1139 | 0.0900 | 0.6236 | 0.7153 | 0.0010 | 0.0023 | 0.0048 | 0.0053 | 0.0120 | 0.0164 | 0.0307 | 0.0282 | 0.0801 | 0.0921 | 0.1243 | 0.1268 | 0.0998 | 0.1009 | 0.1166 | 0.1291 | 0.5307 | 0.4988 | 0.0004 | 0.0020 | 0.0086 | 0.0207 | 0.0718 | 0.1128 | 0.0910 | 0.1175 | 0.5752 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 212 | 744 | | 6614 | 10325 | 163.1 | 32.35 | 119.28 | 84.78 | 125 | 138 | 147 | 155 | 161 | 167 | 175 | 185 | 203 | 0.0792 | 818 | 1.172 | 127.35 | 40.25 | 1 | 0.0452 | 299 | 0.0020 | 27.70 | 6.559 | 0.2300 | 27650.6 | 4880000 | 902000000 | 175000000000 | 0.4500 | 0.2031 | 0.0002 | 0.0000 | 0.0008 | 0.0003 | 0.0033 | 0.0005 | 0.0157 | 0.0009 | 0.0518 | 0.0158 | 0.1045 | 0.0311 | 0.1239 | 0.0356 | 0.1680 | 0.0538 | 0.5318 | 0.8621 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0073 | 0.0005 | 0.0238 | 0.0110 | 0.0514 | 0.0224 | 0.0550 | 0.0146 | 0.0835 | 0.0286 | 0.7771 | 0.9229 | 0.0114 | 0.0090 | 0.0194 | 0.0495 | 0.0411 | 0.0495 | 0.1006 | 0.1802 | 0.1600 | 0.2117 | 0.1794 | 0.1757 | 0.1486 | 0.0991 | 0.1394 | 0.0991 | 0.2000 | 0.1261 | 0.0006 | 0.0063 | 0.0157 | 0.0466 | 0.0913 | 0.1326 | 0.1222 | 0.1698 | 0.4148 | 30 | 47 | 62 | 79 | 97 | 119 | 148 | 185 | 240 | 0.0026 | 32.10 | 6.579 | 0.2832 | 21415.5 | 4970000 | 1370000000 | 425000000000 | 0.5726 | 0.1051 | 0.0233 | 0.0012 | 0.1341 | 0.0059 | 0.2743 | 0.0446 | 0.1832 | 0.1006 | 0.1522 | 0.1877 | 0.1071 | 0.1954 | 0.0694 | 0.1475 | 0.0367 | 0.1460 | 0.0197 | 0.1709 | 0.0004 | 0.0005 | 0.0023 | 0.0009 | 0.0082 | 0.0027 | 0.0218 | 0.0148 | 0.0827 | 0.0624 | 0.1269 | 0.0968 | 0.1019 | 0.0859 | 0.1392 | 0.1237 | 0.5166 | 0.6124 | 0.0015 | 0.0023 | 0.0073 | 0.0051 | 0.0094 | 0.0167 | 0.0462 | 0.0607 | 0.1152 | 0.1293 | 0.1711 | 0.1795 | 0.1100 | 0.1215 | 0.1510 | 0.1484 | 0.3883 | 0.3364 | 0.0007 | 0.0041 | 0.0070 | 0.0374 | 0.0934 | 0.1539 | 0.1074 | 0.1421 | 0.4540 | ||
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 989 | 569 | | 11363 | 17154 | 435.1 | 102.14 | 100.15 | 106.92 | 319 | 350 | 374 | 396 | 420 | 445 | 475 | 519 | 577 | 0.0642 | 1102 | 1.214 | 111.97 | 45.88 | 1 | 0.0259 | 294 | 0.0008 | 45.10 | 7.457 | 0.1791 | 199761.0 | 96800000 | 49400000000 | 26500000000000 | 0.4356 | 0.2162 | 0.0004 | 0.0001 | 0.0023 | 0.0001 | 0.0049 | 0.0006 | 0.0187 | 0.0024 | 0.0547 | 0.0168 | 0.1228 | 0.0359 | 0.1224 | 0.0361 | 0.1532 | 0.0537 | 0.5207 | 0.8544 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0001 | 0.0074 | 0.0009 | 0.0262 | 0.0104 | 0.0589 | 0.0186 | 0.0605 | 0.0168 | 0.0788 | 0.0275 | 0.7659 | 0.9258 | 0.0027 | 0.0014 | 0.0063 | 0.0068 | 0.0094 | 0.0315 | 0.0367 | 0.0876 | 0.0823 | 0.1231 | 0.1360 | 0.1737 | 0.0922 | 0.1081 | 0.1128 | 0.1231 | 0.5217 | 0.3447 | 0.0010 | 0.0012 | 0.0068 | 0.0319 | 0.0806 | 0.1097 | 0.0930 | 0.1123 | 0.5635 | 7 | 11 | 20 | 37 | 62 | 94 | 132 | 180 | 248 | 0.0392 | 11.55 | 4.988 | 0.4732 | 21460.8 | 6340000 | 2300000000 | 971000000000 | 0.5515 | 0.1124 | 0.0581 | 0.0039 | 0.2164 | 0.0200 | 0.2885 | 0.1377 | 0.1593 | 0.1383 | 0.1259 | 0.1997 | 0.0867 | 0.1917 | 0.0344 | 0.1180 | 0.0237 | 0.1032 | 0.0070 | 0.0874 | 0.0001 | 0.0001 | 0.0005 | 0.0005 | 0.0012 | 0.0003 | 0.0130 | 0.0092 | 0.0667 | 0.0520 | 0.1087 | 0.0943 | 0.0812 | 0.0656 | 0.1186 | 0.1022 | 0.6099 | 0.6759 | 0.0005 | 0.0012 | 0.0010 | 0.0029 | 0.0045 | 0.0074 | 0.0218 | 0.0286 | 0.0939 | 0.1036 | 0.1590 | 0.1785 | 0.0997 | 0.1088 | 0.1431 | 0.1573 | 0.4763 | 0.4118 | 0.0003 | 0.0006 | 0.0018 | 0.0174 | 0.0781 | 0.1316 | 0.0944 | 0.1376 | 0.5381 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 767 | 375 | | 10994 | 36702 | 317.2 | 66.33 | 88.78 | 117.60 | 238 | 259 | 276 | 292 | 309 | 327 | 346 | 373 | 410 | 0.0385 | 1412 | 0.777 | 113.02 | 23.02 | 1 | 0.0226 | 249 | 0.0006 | 70.27 | 7.726 | 0.1479 | 104984.0 | 36300000 | 13000000000 | 4880000000000 | 0.4228 | 0.2250 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0001 | 0.0125 | 0.0008 | 0.0612 | 0.0134 | 0.1259 | 0.0305 | 0.1295 | 0.0324 | 0.1666 | 0.0567 | 0.4994 | 0.8660 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0062 | 0.0003 | 0.0265 | 0.0088 | 0.0510 | 0.0177 | 0.0541 | 0.0124 | 0.0766 | 0.0239 | 0.7828 | 0.9370 | 0.0031 | 0.0102 | 0.0078 | 0.0225 | 0.0225 | 0.0758 | 0.0628 | 0.1250 | 0.1313 | 0.1557 | 0.1763 | 0.1475 | 0.1104 | 0.1025 | 0.1423 | 0.1270 | 0.3433 | 0.2336 | 0.0010 | 0.0030 | 0.0062 | 0.0294 | 0.0726 | 0.1184 | 0.1031 | 0.1345 | 0.5318 | 10 | 12 | 14 | 19 | 32 | 55 | 97 | 156 | 255 | 0.0788 | 13.52 | 4.639 | 0.5538 | 21712.5 | 8010000 | 3800000000 | 2180000000000 | 0.4103 | 0.2154 | 0.0637 | 0.0009 | 0.2390 | 0.0098 | 0.3525 | 0.1068 | 0.1643 | 0.1924 | 0.0959 | 0.2534 | 0.0480 | 0.2004 | 0.0216 | 0.1040 | 0.0113 | 0.0742 | 0.0037 | 0.0580 | 0.0002 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0012 | 0.0109 | 0.0097 | 0.0639 | 0.0507 | 0.0964 | 0.0843 | 0.0715 | 0.0616 | 0.1087 | 0.0931 | 0.6473 | 0.6989 | 0.0002 | 0.0004 | 0.0011 | 0.0016 | 0.0034 | 0.0043 | 0.0175 | 0.0189 | 0.0814 | 0.0927 | 0.1222 | 0.1338 | 0.0853 | 0.0887 | 0.1273 | 0.1253 | 0.5616 | 0.5343 | 0.0001 | 0.0004 | 0.0016 | 0.0110 | 0.0724 | 0.1147 | 0.0774 | 0.1169 | 0.6055 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 892 | 808 | | 6094 | 19347 | 103.4 | 22.94 | 122.27 | 83.90 | 75 | 85 | 92 | 97 | 102 | 107 | 112 | 121 | 133 | 0.0484 | 936 | 1.125 | 94.85 | 31.83 | 1 | 0.0392 | 239 | 0.0039 | 10.98 | 5.900 | 0.3264 | 11210.4 | 1270000 | 152000000 | 18900000000 | 0.4570 | 0.2021 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0075 | 0.0005 | 0.0217 | 0.0025 | 0.0681 | 0.0209 | 0.1205 | 0.0436 | 0.1287 | 0.0444 | 0.1709 | 0.0652 | 0.4814 | 0.8229 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0008 | 0.0003 | 0.0057 | 0.0008 | 0.0301 | 0.0158 | 0.0611 | 0.0257 | 0.0577 | 0.0203 | 0.0864 | 0.0360 | 0.7580 | 0.9009 | 0.0048 | 0.0034 | 0.0114 | 0.0034 | 0.0362 | 0.0638 | 0.0744 | 0.1577 | 0.1459 | 0.1745 | 0.1582 | 0.1980 | 0.1049 | 0.1040 | 0.1316 | 0.0973 | 0.3327 | 0.1980 | 0.0024 | 0.0044 | 0.0131 | 0.0346 | 0.0831 | 0.1291 | 0.1133 | 0.1439 | 0.4761 | 33 | 51 | 65 | 82 | 103 | 126 | 154 | 189 | 241 | 0.0030 | 24.00 | 6.471 | 0.3279 | 21987.3 | 5050000 | 1370000000 | 426000000000 | 0.5315 | 0.1249 | 0.0083 | 0.0021 | 0.0440 | 0.0066 | 0.1311 | 0.0164 | 0.1593 | 0.0533 | 0.1961 | 0.1147 | 0.1767 | 0.1669 | 0.1247 | 0.1521 | 0.0905 | 0.1695 | 0.0693 | 0.3187 | 0.0010 | 0.0006 | 0.0013 | 0.0017 | 0.0036 | 0.0031 | 0.0138 | 0.0108 | 0.0495 | 0.0346 | 0.0872 | 0.0628 | 0.0752 | 0.0624 | 0.1022 | 0.0842 | 0.6663 | 0.7398 | 0.0013 | 0.0023 | 0.0050 | 0.0054 | 0.0129 | 0.0159 | 0.0312 | 0.0399 | 0.0778 | 0.0899 | 0.1203 | 0.1442 | 0.1048 | 0.1188 | 0.1379 | 0.1445 | 0.5089 | 0.4391 | 0.0010 | 0.0027 | 0.0081 | 0.0215 | 0.0651 | 0.1056 | 0.0949 | 0.1211 | 0.5800 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1174 | 846 | | 5064 | 8048 | 118.7 | 34.40 | 119.92 | 88.88 | 80 | 91 | 100 | 107 | 114 | 121 | 130 | 142 | 161 | 0.1006 | 810 | 1.202 | 110.39 | 36.80 | 1 | 0.0519 | 263 | 0.0023 | 19.24 | 6.374 | 0.2651 | 15273.8 | 2150000 | 332000000 | 57200000000 | 0.4585 | 0.1999 | 0.0000 | 0.0000 | 0.0032 | 0.0011 | 0.0165 | 0.0029 | 0.0330 | 0.0052 | 0.0979 | 0.0270 | 0.1707 | 0.0583 | 0.1528 | 0.0615 | 0.1854 | 0.1097 | 0.3404 | 0.7342 | 0.0000 | 0.0000 | 0.0008 | 0.0004 | 0.0053 | 0.0010 | 0.0127 | 0.0016 | 0.0433 | 0.0179 | 0.0763 | 0.0324 | 0.0610 | 0.0311 | 0.0971 | 0.0575 | 0.7036 | 0.8580 | 0.0060 | 0.0218 | 0.0060 | 0.0170 | 0.0320 | 0.0243 | 0.0659 | 0.0898 | 0.1229 | 0.1723 | 0.1758 | 0.2112 | 0.1269 | 0.1092 | 0.1479 | 0.1286 | 0.3167 | 0.2257 | 0.0027 | 0.0018 | 0.0121 | 0.0318 | 0.0854 | 0.1239 | 0.0962 | 0.1395 | 0.5067 | 18 | 37 | 59 | 82 | 107 | 129 | 156 | 187 | 238 | 0.0034 | 26.76 | 6.490 | 0.3055 | 22278.7 | 5270000 | 1470000000 | 464000000000 | 0.4991 | 0.1573 | 0.0146 | 0.0016 | 0.0781 | 0.0070 | 0.1684 | 0.0269 | 0.1775 | 0.0701 | 0.1891 | 0.1509 | 0.1647 | 0.1985 | 0.1031 | 0.1722 | 0.0653 | 0.1630 | 0.0390 | 0.2099 | 0.0007 | 0.0004 | 0.0032 | 0.0006 | 0.0057 | 0.0038 | 0.0214 | 0.0111 | 0.0578 | 0.0521 | 0.1026 | 0.0899 | 0.0839 | 0.0694 | 0.1046 | 0.0895 | 0.6202 | 0.6832 | 0.0022 | 0.0015 | 0.0051 | 0.0176 | 0.0138 | 0.0263 | 0.0377 | 0.0512 | 0.1048 | 0.1146 | 0.1247 | 0.1258 | 0.1215 | 0.1107 | 0.1265 | 0.1287 | 0.4637 | 0.4237 | 0.0006 | 0.0028 | 0.0104 | 0.0254 | 0.0725 | 0.1253 | 0.1041 | 0.1202 | 0.5387 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1240 | 782 | | 5520 | 5479 | 133.2 | 23.75 | 110.66 | 100.88 | 104 | 113 | 119 | 126 | 132 | 138 | 144 | 152 | 163 | 0.1374 | 753 | 0.999 | 91.29 | 24.70 | 1 | 0.0397 | 219 | 0.0031 | 14.38 | 6.066 | 0.2851 | 18294.8 | 2590000 | 379000000 | 57200000000 | 0.4125 | 0.2388 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0002 | 0.0212 | 0.0007 | 0.0442 | 0.0156 | 0.0934 | 0.0282 | 0.1204 | 0.0252 | 0.1646 | 0.0404 | 0.5507 | 0.8897 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0083 | 0.0002 | 0.0228 | 0.0129 | 0.0452 | 0.0203 | 0.0504 | 0.0132 | 0.0765 | 0.0234 | 0.7949 | 0.9300 | 0.0226 | 0.0169 | 0.0155 | 0.0763 | 0.0523 | 0.1102 | 0.1088 | 0.1102 | 0.1638 | 0.1525 | 0.1723 | 0.2034 | 0.1201 | 0.1356 | 0.1554 | 0.0847 | 0.1893 | 0.1102 | 0.0033 | 0.0089 | 0.0118 | 0.0380 | 0.0687 | 0.1048 | 0.1063 | 0.1384 | 0.5197 | 27 | 36 | 47 | 60 | 75 | 95 | 123 | 168 | 249 | 0.0062 | 29.53 | 5.971 | 0.3642 | 22419.6 | 6640000 | 2430000000 | 1010000000000 | 0.6287 | 0.0903 | 0.0259 | 0.0043 | 0.1147 | 0.0103 | 0.2160 | 0.0511 | 0.1732 | 0.0983 | 0.1395 | 0.1836 | 0.1192 | 0.1825 | 0.0934 | 0.1477 | 0.0742 | 0.1266 | 0.0439 | 0.1955 | 0.0017 | 0.0020 | 0.0034 | 0.0039 | 0.0089 | 0.0098 | 0.0326 | 0.0219 | 0.0852 | 0.0732 | 0.1360 | 0.1023 | 0.1004 | 0.0859 | 0.1513 | 0.1366 | 0.4805 | 0.5644 | 0.0020 | 0.0025 | 0.0095 | 0.0033 | 0.0102 | 0.0172 | 0.0428 | 0.0582 | 0.1292 | 0.1534 | 0.1747 | 0.1838 | 0.1237 | 0.1017 | 0.1475 | 0.1403 | 0.3603 | 0.3396 | 0.0016 | 0.0064 | 0.0155 | 0.0321 | 0.1095 | 0.1474 | 0.1239 | 0.1394 | 0.4241 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 214 | 52 | | 4675 | 12509 | 132.0 | 40.47 | 117.04 | 94.59 | 92 | 100 | 107 | 113 | 121 | 132 | 145 | 161 | 189 | 0.0803 | 1005 | 0.655 | 96.30 | 21.02 | 2 | 0.0560 | 262 | 0.0021 | 28.90 | 6.597 | 0.2326 | 19052.3 | 3020000 | 527000000 | 100000000000 | 0.4138 | 0.2308 | 0.0008 | 0.0003 | 0.0068 | 0.0003 | 0.0194 | 0.0015 | 0.0520 | 0.0078 | 0.1348 | 0.0341 | 0.1753 | 0.0664 | 0.1715 | 0.0721 | 0.1800 | 0.1079 | 0.2594 | 0.7097 | 0.0006 | 0.0000 | 0.0027 | 0.0000 | 0.0104 | 0.0007 | 0.0207 | 0.0027 | 0.0584 | 0.0188 | 0.0768 | 0.0358 | 0.0788 | 0.0298 | 0.1108 | 0.0522 | 0.6408 | 0.8601 | 0.0020 | 0.0038 | 0.0070 | 0.0150 | 0.0209 | 0.0282 | 0.0407 | 0.0846 | 0.1132 | 0.1372 | 0.1420 | 0.1541 | 0.1231 | 0.1316 | 0.1480 | 0.1447 | 0.4032 | 0.3008 | 0.0021 | 0.0043 | 0.0134 | 0.0417 | 0.0759 | 0.1027 | 0.0861 | 0.1294 | 0.5444 | 26 | 40 | 56 | 73 | 92 | 113 | 140 | 176 | 239 | 0.0031 | 25.48 | 6.462 | 0.3039 | 22644.4 | 6150000 | 2080000000 | 812000000000 | 0.4477 | 0.1962 | 0.0142 | 0.0021 | 0.0519 | 0.0093 | 0.1197 | 0.0219 | 0.1744 | 0.0608 | 0.1903 | 0.1276 | 0.1761 | 0.1685 | 0.1335 | 0.1621 | 0.0917 | 0.1797 | 0.0483 | 0.2680 | 0.0015 | 0.0008 | 0.0032 | 0.0034 | 0.0108 | 0.0069 | 0.0246 | 0.0184 | 0.0594 | 0.0480 | 0.0968 | 0.0772 | 0.0801 | 0.0743 | 0.1071 | 0.1012 | 0.6165 | 0.6698 | 0.0048 | 0.0042 | 0.0083 | 0.0087 | 0.0124 | 0.0192 | 0.0423 | 0.0439 | 0.0721 | 0.0829 | 0.1074 | 0.1257 | 0.0921 | 0.1041 | 0.1327 | 0.1351 | 0.5279 | 0.4761 | 0.0027 | 0.0064 | 0.0140 | 0.0311 | 0.0705 | 0.1082 | 0.0827 | 0.1082 | 0.5761 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1025 | 533 | | 6415 | 17497 | 136.2 | 34.04 | 109.48 | 103.79 | 91 | 104 | 115 | 126 | 135 | 145 | 155 | 165 | 181 | 0.0768 | 1343 | 1.143 | 110.98 | 37.59 | 5 | 0.0415 | 266 | 0.0020 | 17.74 | 6.447 | 0.2724 | 19709.7 | 3010000 | 484000000 | 81300000000 | 0.4281 | 0.2171 | 0.0017 | 0.0000 | 0.0060 | 0.0009 | 0.0083 | 0.0029 | 0.0252 | 0.0062 | 0.0809 | 0.0210 | 0.1181 | 0.0496 | 0.1378 | 0.0503 | 0.1704 | 0.0722 | 0.4515 | 0.7970 | 0.0002 | 0.0000 | 0.0023 | 0.0005 | 0.0016 | 0.0016 | 0.0072 | 0.0042 | 0.0297 | 0.0146 | 0.0462 | 0.0299 | 0.0467 | 0.0256 | 0.0632 | 0.0341 | 0.8029 | 0.8896 | 0.0050 | 0.0107 | 0.0137 | 0.0134 | 0.0281 | 0.0588 | 0.0518 | 0.1070 | 0.0978 | 0.1765 | 0.1259 | 0.2005 | 0.1295 | 0.1150 | 0.1489 | 0.1283 | 0.3993 | 0.1898 | 0.0003 | 0.0025 | 0.0041 | 0.0194 | 0.0484 | 0.0871 | 0.0787 | 0.1052 | 0.6544 | 23 | 35 | 46 | 58 | 72 | 92 | 123 | 171 | 248 | 0.0137 | 12.49 | 5.314 | 0.4876 | 22756.3 | 7180000 | 2950000000 | 1450000000000 | 0.5455 | 0.1639 | 0.0152 | 0.0037 | 0.0629 | 0.0119 | 0.1464 | 0.0290 | 0.2021 | 0.0594 | 0.2186 | 0.1394 | 0.1738 | 0.1927 | 0.0924 | 0.1541 | 0.0557 | 0.1495 | 0.0329 | 0.2603 | 0.0008 | 0.0018 | 0.0032 | 0.0044 | 0.0073 | 0.0078 | 0.0221 | 0.0165 | 0.0575 | 0.0523 | 0.0972 | 0.0769 | 0.0694 | 0.0675 | 0.0930 | 0.0837 | 0.6497 | 0.6889 | 0.0020 | 0.0015 | 0.0045 | 0.0037 | 0.0134 | 0.0110 | 0.0213 | 0.0282 | 0.0764 | 0.0849 | 0.1103 | 0.1288 | 0.0855 | 0.0952 | 0.1156 | 0.1242 | 0.5710 | 0.5225 | 0.0015 | 0.0052 | 0.0074 | 0.0247 | 0.0649 | 0.1051 | 0.0778 | 0.1034 | 0.6100 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1142 | 857 | | 7401 | 14616 | 171.0 | 66.26 | 71.29 | 133.72 | 97 | 113 | 126 | 141 | 159 | 177 | 198 | 227 | 267 | 0.0757 | 1106 | 0.455 | 200.25 | 41.00 | 7 | 0.0947 | 701 | 0.0014 | 22.02 | 6.984 | 0.2885 | 33621.9 | 7480000 | 1840000000 | 492000000000 | 0.3427 | 0.2805 | 0.0023 | 0.0008 | 0.0023 | 0.0025 | 0.0164 | 0.0059 | 0.0279 | 0.0086 | 0.0707 | 0.0301 | 0.1250 | 0.0604 | 0.1170 | 0.0539 | 0.1514 | 0.0722 | 0.4868 | 0.7658 | 0.0004 | 0.0005 | 0.0013 | 0.0012 | 0.0054 | 0.0022 | 0.0073 | 0.0043 | 0.0207 | 0.0130 | 0.0326 | 0.0254 | 0.0318 | 0.0221 | 0.0443 | 0.0300 | 0.8561 | 0.9014 | 0.0010 | 0.0000 | 0.0030 | 0.0041 | 0.0094 | 0.0058 | 0.0189 | 0.0386 | 0.0506 | 0.0641 | 0.0839 | 0.1191 | 0.0645 | 0.0994 | 0.0948 | 0.1224 | 0.6738 | 0.5464 | 0.0012 | 0.0025 | 0.0065 | 0.0109 | 0.0349 | 0.0477 | 0.0514 | 0.0767 | 0.7681 | 10 | 12 | 14 | 16 | 20 | 33 | 59 | 100 | 185 | 0.1556 | 7.37 | 3.609 | 0.6941 | 22963.2 | 18300000 | 21700000000 | 29800000000000 | 0.5623 | 0.1121 | 0.0192 | 0.0013 | 0.1028 | 0.0217 | 0.1742 | 0.0579 | 0.2030 | 0.0744 | 0.1838 | 0.1431 | 0.1324 | 0.1783 | 0.0941 | 0.1601 | 0.0662 | 0.1353 | 0.0244 | 0.2279 | 0.0000 | 0.0002 | 0.0020 | 0.0025 | 0.0051 | 0.0046 | 0.0151 | 0.0122 | 0.0523 | 0.0408 | 0.0785 | 0.0615 | 0.0621 | 0.0522 | 0.0923 | 0.0762 | 0.6926 | 0.7500 | 0.0006 | 0.0003 | 0.0012 | 0.0037 | 0.0062 | 0.0075 | 0.0211 | 0.0251 | 0.0699 | 0.0728 | 0.1077 | 0.1162 | 0.0759 | 0.0799 | 0.1107 | 0.1118 | 0.6067 | 0.5827 | 0.0003 | 0.0008 | 0.0031 | 0.0230 | 0.0637 | 0.0872 | 0.0730 | 0.0993 | 0.6497 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 287 | 208 | | 5091 | 12471 | 474.1 | 73.02 | 68.38 | 135.66 | 363 | 414 | 452 | 475 | 490 | 504 | 518 | 533 | 553 | 0.0763 | 952 | 1.174 | 64.62 | 19.85 | 1 | 0.0297 | 151 | 0.0020 | 19.65 | 6.571 | 0.2736 | 230087.0 | 114000000 | 57200000000 | 29100000000000 | 0.4330 | 0.2034 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0074 | 0.0012 | 0.0203 | 0.0121 | 0.0432 | 0.0234 | 0.0404 | 0.0127 | 0.0650 | 0.0183 | 0.8215 | 0.9322 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0032 | 0.0012 | 0.0131 | 0.0121 | 0.0257 | 0.0234 | 0.0181 | 0.0127 | 0.0235 | 0.0183 | 0.9163 | 0.9322 | 0.0328 | 0.0000 | 0.0615 | 0.0000 | 0.1025 | 0.0000 | 0.1311 | 0.0000 | 0.1352 | 0.0000 | 0.1352 | 0.0000 | 0.1230 | 0.0000 | 0.0820 | 0.0000 | 0.1967 | 0.0000 | 0.0000 | 0.0026 | 0.0065 | 0.0091 | 0.0308 | 0.0587 | 0.0532 | 0.0834 | 0.7557 | 6 | 8 | 9 | 11 | 15 | 21 | 36 | 71 | 216 | 0.1260 | 12.46 | 3.408 | 0.6217 | 23078.9 | 13100000 | 9690000000 | 8870000000000 | 0.4949 | 0.1599 | 0.0417 | 0.0057 | 0.1106 | 0.0278 | 0.1571 | 0.0785 | 0.1234 | 0.0849 | 0.1619 | 0.1091 | 0.1250 | 0.1320 | 0.1106 | 0.1084 | 0.1090 | 0.1434 | 0.0609 | 0.3103 | 0.0024 | 0.0014 | 0.0044 | 0.0028 | 0.0051 | 0.0068 | 0.0139 | 0.0160 | 0.0493 | 0.0376 | 0.0748 | 0.0673 | 0.0479 | 0.0450 | 0.0816 | 0.0730 | 0.7206 | 0.7501 | 0.0000 | 0.0014 | 0.0017 | 0.0009 | 0.0043 | 0.0047 | 0.0181 | 0.0161 | 0.0513 | 0.0584 | 0.0945 | 0.1011 | 0.0513 | 0.0570 | 0.0815 | 0.0783 | 0.6972 | 0.6820 | 0.0008 | 0.0012 | 0.0043 | 0.0152 | 0.0519 | 0.0831 | 0.0542 | 0.0807 | 0.7087 | ||
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 561 | 247 | | 4445 | 15033 | 466.1 | 65.09 | 63.62 | 138.06 | 379 | 413 | 433 | 450 | 466 | 481 | 499 | 521 | 551 | 0.0559 | 840 | 1.186 | 46.40 | 17.49 | 1 | 0.0270 | 120 | 0.0015 | 34.76 | 6.820 | 0.2169 | 221513.0 | 107000000 | 52800000000 | 26400000000000 | 0.4116 | 0.2311 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0035 | 0.0002 | 0.0355 | 0.0137 | 0.0646 | 0.0248 | 0.0635 | 0.0142 | 0.0910 | 0.0205 | 0.7407 | 0.9266 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0002 | 0.0221 | 0.0137 | 0.0368 | 0.0248 | 0.0314 | 0.0142 | 0.0456 | 0.0187 | 0.8620 | 0.9284 | 0.0110 | 1.0000 | 0.0192 | 0.0000 | 0.0219 | 0.0000 | 0.0959 | 0.0000 | 0.1479 | 0.0000 | 0.1726 | 0.0000 | 0.1397 | 0.0000 | 0.1288 | 0.0000 | 0.2630 | 0.0000 | 0.0004 | 0.0036 | 0.0085 | 0.0278 | 0.0732 | 0.0996 | 0.0961 | 0.1302 | 0.5606 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 57 | 200 | 0.2619 | 11.61 | 3.053 | 0.7574 | 23105.5 | 14100000 | 11000000000 | 10100000000000 | 0.4691 | 0.1844 | 0.0363 | 0.0081 | 0.0726 | 0.0208 | 0.0726 | 0.0728 | 0.1501 | 0.0786 | 0.1622 | 0.1110 | 0.1671 | 0.1260 | 0.1574 | 0.1191 | 0.1090 | 0.1445 | 0.0726 | 0.3191 | 0.0003 | 0.0012 | 0.0013 | 0.0030 | 0.0023 | 0.0044 | 0.0077 | 0.0094 | 0.0229 | 0.0195 | 0.0265 | 0.0301 | 0.0245 | 0.0248 | 0.0368 | 0.0387 | 0.8777 | 0.8689 | 0.0011 | 0.0000 | 0.0011 | 0.0004 | 0.0022 | 0.0024 | 0.0108 | 0.0091 | 0.0238 | 0.0234 | 0.0309 | 0.0313 | 0.0313 | 0.0317 | 0.0395 | 0.0527 | 0.8593 | 0.8490 | 0.0003 | 0.0007 | 0.0048 | 0.0104 | 0.0214 | 0.0308 | 0.0235 | 0.0443 | 0.8637 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 474 | 145 | | 2157 | 11213 | 221.6 | 78.59 | 65.05 | 137.53 | 132 | 156 | 176 | 192 | 207 | 222 | 245 | 295 | 349 | 0.0538 | 603 | 0.725 | 94.64 | 21.02 | 1 | 0.1136 | 245 | 0.0010 | 66.86 | 7.099 | 0.1610 | 55259.5 | 15300000 | 4580000000 | 1470000000000 | 0.4001 | 0.2354 | 0.0011 | 0.0000 | 0.0000 | 0.0013 | 0.0064 | 0.0032 | 0.0416 | 0.0121 | 0.0928 | 0.0490 | 0.1738 | 0.0732 | 0.1525 | 0.0803 | 0.1514 | 0.0968 | 0.3806 | 0.6841 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0027 | 0.0010 | 0.0148 | 0.0073 | 0.0425 | 0.0250 | 0.0748 | 0.0374 | 0.0742 | 0.0421 | 0.0883 | 0.0525 | 0.7026 | 0.8341 | 0.0055 | 0.0028 | 0.0037 | 0.0000 | 0.0073 | 0.0085 | 0.0147 | 0.0312 | 0.0569 | 0.0708 | 0.0734 | 0.1246 | 0.0477 | 0.1161 | 0.0734 | 0.1161 | 0.7174 | 0.5297 | 0.0000 | 0.0092 | 0.0035 | 0.0403 | 0.0909 | 0.0967 | 0.0748 | 0.0748 | 0.6099 | 12 | 14 | 15 | 17 | 18 | 20 | 25 | 45 | 176 | 0.1489 | 17.64 | 3.226 | 0.6746 | 23145.6 | 15600000 | 14100000000 | 15200000000000 | 0.6928 | 0.0672 | 0.0631 | 0.0192 | 0.1329 | 0.0266 | 0.2691 | 0.0932 | 0.2060 | 0.1391 | 0.1761 | 0.1953 | 0.1030 | 0.1982 | 0.0399 | 0.1450 | 0.0100 | 0.1109 | 0.0000 | 0.0725 | 0.0000 | 0.0037 | 0.0009 | 0.0029 | 0.0023 | 0.0054 | 0.0089 | 0.0125 | 0.0455 | 0.0432 | 0.0829 | 0.0602 | 0.0590 | 0.0557 | 0.0890 | 0.0798 | 0.7113 | 0.7366 | 0.0000 | 0.0000 | 0.0005 | 0.0006 | 0.0016 | 0.0023 | 0.0104 | 0.0116 | 0.0595 | 0.0687 | 0.1075 | 0.1167 | 0.0797 | 0.0797 | 0.1151 | 0.1358 | 0.6258 | 0.5846 | 0.0000 | 0.0010 | 0.0005 | 0.0090 | 0.0562 | 0.0853 | 0.0693 | 0.1094 | 0.6692 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1074 | 767 | | 4851 | 8558 | 206.5 | 55.00 | 108.27 | 109.37 | 139 | 160 | 174 | 187 | 202 | 217 | 232 | 251 | 282 | 0.1187 | 1016 | 0.484 | 105.59 | 20.81 | 4 | 0.0662 | 321 | 0.0008 | 57.36 | 7.309 | 0.1587 | 45680.7 | 10800000 | 2680000000 | 703000000000 | 0.4637 | 0.1868 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0086 | 0.0009 | 0.0413 | 0.0069 | 0.0994 | 0.0313 | 0.1640 | 0.0778 | 0.1659 | 0.0680 | 0.1872 | 0.1041 | 0.3321 | 0.7110 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0019 | 0.0006 | 0.0119 | 0.0039 | 0.0380 | 0.0199 | 0.0697 | 0.0448 | 0.0629 | 0.0307 | 0.0941 | 0.0474 | 0.7209 | 0.8527 | 0.0078 | 0.0123 | 0.0059 | 0.0123 | 0.0157 | 0.0567 | 0.0793 | 0.0961 | 0.1360 | 0.1995 | 0.1634 | 0.1847 | 0.1164 | 0.1059 | 0.1585 | 0.1256 | 0.3170 | 0.2069 | 0.0000 | 0.0013 | 0.0048 | 0.0255 | 0.0867 | 0.1175 | 0.1122 | 0.1373 | 0.5147 | 12 | 18 | 29 | 47 | 69 | 99 | 134 | 187 | 268 | 0.0244 | 13.32 | 5.257 | 0.4878 | 23683.4 | 7140000 | 2580000000 | 1050000000000 | 0.5580 | 0.1201 | 0.0405 | 0.0014 | 0.1364 | 0.0151 | 0.1957 | 0.0713 | 0.2286 | 0.1138 | 0.1722 | 0.1731 | 0.1091 | 0.2097 | 0.0640 | 0.1398 | 0.0301 | 0.1316 | 0.0235 | 0.1444 | 0.0008 | 0.0007 | 0.0029 | 0.0009 | 0.0080 | 0.0059 | 0.0252 | 0.0204 | 0.0707 | 0.0557 | 0.1162 | 0.1042 | 0.0849 | 0.0847 | 0.1154 | 0.1074 | 0.5760 | 0.6202 | 0.0007 | 0.0027 | 0.0045 | 0.0063 | 0.0142 | 0.0144 | 0.0359 | 0.0395 | 0.0864 | 0.0997 | 0.1253 | 0.1307 | 0.1029 | 0.1150 | 0.1377 | 0.1370 | 0.4923 | 0.4546 | 0.0019 | 0.0031 | 0.0084 | 0.0273 | 0.0769 | 0.1256 | 0.0924 | 0.1293 | 0.5352 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1013 | 682 | | 13732 | 29163 | 489.2 | 88.51 | 64.45 | 140.69 | 369 | 416 | 448 | 471 | 492 | 513 | 535 | 561 | 598 | 0.0441 | 1286 | 0.817 | 91.92 | 19.24 | 13 | 0.0163 | 224 | 0.0009 | 42.91 | 7.350 | 0.2018 | 247158.0 | 129000000 | 68600000000 | 37500000000000 | 0.4764 | 0.1806 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0010 | 0.0002 | 0.0078 | 0.0008 | 0.0407 | 0.0122 | 0.0790 | 0.0262 | 0.0719 | 0.0181 | 0.1073 | 0.0285 | 0.6912 | 0.9139 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0001 | 0.0000 | 0.0022 | 0.0004 | 0.0199 | 0.0104 | 0.0412 | 0.0212 | 0.0321 | 0.0132 | 0.0499 | 0.0202 | 0.8544 | 0.9345 | 0.0040 | 0.0187 | 0.0103 | 0.0327 | 0.0343 | 0.0467 | 0.0623 | 0.0561 | 0.1189 | 0.1402 | 0.1320 | 0.2150 | 0.0971 | 0.1122 | 0.1223 | 0.1636 | 0.4189 | 0.2150 | 0.0010 | 0.0013 | 0.0046 | 0.0192 | 0.0608 | 0.1022 | 0.0895 | 0.1194 | 0.6020 | 6 | 7 | 9 | 10 | 11 | 13 | 21 | 61 | 192 | 0.2959 | 12.61 | 3.087 | 0.7489 | 23946.5 | 14200000 | 10300000000 | 8680000000000 | 0.5403 | 0.1285 | 0.0409 | 0.0032 | 0.1110 | 0.0290 | 0.1519 | 0.0767 | 0.1548 | 0.0965 | 0.1500 | 0.1282 | 0.1519 | 0.1650 | 0.1042 | 0.1195 | 0.0828 | 0.1232 | 0.0526 | 0.2587 | 0.0003 | 0.0007 | 0.0006 | 0.0010 | 0.0021 | 0.0026 | 0.0106 | 0.0112 | 0.0421 | 0.0350 | 0.0683 | 0.0631 | 0.0405 | 0.0400 | 0.0644 | 0.0618 | 0.7712 | 0.7846 | 0.0002 | 0.0000 | 0.0013 | 0.0008 | 0.0025 | 0.0025 | 0.0115 | 0.0135 | 0.0507 | 0.0532 | 0.0788 | 0.0824 | 0.0465 | 0.0475 | 0.0710 | 0.0731 | 0.7375 | 0.7270 | 0.0007 | 0.0010 | 0.0017 | 0.0150 | 0.0416 | 0.0733 | 0.0472 | 0.0663 | 0.7529 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 429 | 152 | | 5147 | 13190 | 300.5 | 77.17 | 108.66 | 110.80 | 212 | 234 | 254 | 271 | 289 | 308 | 329 | 359 | 403 | 0.0728 | 960 | 0.674 | 104.17 | 19.70 | 1 | 0.0492 | 253 | 0.0006 | 94.37 | 7.666 | 0.1240 | 96226.5 | 32900000 | 12000000000 | 4710000000000 | 0.3982 | 0.2452 | 0.0017 | 0.0000 | 0.0014 | 0.0000 | 0.0024 | 0.0000 | 0.0279 | 0.0028 | 0.0927 | 0.0245 | 0.1714 | 0.0507 | 0.1714 | 0.0507 | 0.1830 | 0.0752 | 0.3480 | 0.7962 | 0.0013 | 0.0000 | 0.0005 | 0.0000 | 0.0018 | 0.0000 | 0.0109 | 0.0012 | 0.0344 | 0.0148 | 0.0725 | 0.0281 | 0.0803 | 0.0224 | 0.0990 | 0.0368 | 0.6993 | 0.8967 | 0.0020 | 0.0026 | 0.0107 | 0.0104 | 0.0176 | 0.0260 | 0.0547 | 0.0935 | 0.1270 | 0.1636 | 0.1680 | 0.1896 | 0.1240 | 0.1221 | 0.1416 | 0.1377 | 0.3545 | 0.2545 | 0.0004 | 0.0031 | 0.0118 | 0.0298 | 0.0815 | 0.1333 | 0.1109 | 0.1337 | 0.4954 | 12 | 16 | 22 | 38 | 65 | 103 | 146 | 200 | 271 | 0.0288 | 11.68 | 5.216 | 0.4837 | 24083.1 | 7070000 | 2440000000 | 950000000000 | 0.4467 | 0.1953 | 0.0280 | 0.0011 | 0.1405 | 0.0047 | 0.2943 | 0.0614 | 0.1729 | 0.1210 | 0.1545 | 0.2201 | 0.0890 | 0.2000 | 0.0655 | 0.1325 | 0.0361 | 0.1174 | 0.0191 | 0.1418 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0011 | 0.0117 | 0.0076 | 0.0534 | 0.0462 | 0.0876 | 0.0766 | 0.0602 | 0.0517 | 0.0834 | 0.0797 | 0.7018 | 0.7371 | 0.0014 | 0.0008 | 0.0016 | 0.0011 | 0.0036 | 0.0074 | 0.0216 | 0.0198 | 0.0664 | 0.0805 | 0.1074 | 0.1116 | 0.0767 | 0.0818 | 0.1035 | 0.1076 | 0.6178 | 0.5896 | 0.0002 | 0.0006 | 0.0020 | 0.0129 | 0.0649 | 0.0943 | 0.0672 | 0.0976 | 0.6603 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 595 | 443 | | 5995 | 10600 | 127.3 | 28.53 | 123.95 | 93.46 | 93 | 103 | 111 | 117 | 124 | 131 | 139 | 150 | 166 | 0.0878 | 931 | 1.110 | 107.91 | 35.51 | 1 | 0.0454 | 272 | 0.0024 | 17.97 | 6.317 | 0.2686 | 17011.3 | 2390000 | 351000000 | 54200000000 | 0.4279 | 0.2247 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0081 | 0.0009 | 0.0256 | 0.0032 | 0.0811 | 0.0218 | 0.1460 | 0.0470 | 0.1630 | 0.0517 | 0.1863 | 0.0761 | 0.3880 | 0.7993 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0020 | 0.0003 | 0.0092 | 0.0008 | 0.0374 | 0.0147 | 0.0669 | 0.0251 | 0.0697 | 0.0229 | 0.0981 | 0.0354 | 0.7162 | 0.9007 | 0.0056 | 0.0116 | 0.0112 | 0.0462 | 0.0243 | 0.0520 | 0.1104 | 0.1185 | 0.1375 | 0.2110 | 0.1908 | 0.2052 | 0.1272 | 0.1098 | 0.1197 | 0.1214 | 0.2732 | 0.1243 | 0.0029 | 0.0029 | 0.0118 | 0.0319 | 0.0937 | 0.1342 | 0.1202 | 0.1461 | 0.4562 | 21 | 35 | 53 | 77 | 105 | 135 | 167 | 204 | 256 | 0.0045 | 24.94 | 6.421 | 0.3407 | 24096.0 | 5870000 | 1650000000 | 518000000000 | 0.4887 | 0.1638 | 0.0159 | 0.0014 | 0.0819 | 0.0078 | 0.2092 | 0.0351 | 0.1715 | 0.0762 | 0.1821 | 0.1512 | 0.1520 | 0.2185 | 0.0825 | 0.1455 | 0.0631 | 0.1599 | 0.0418 | 0.2044 | 0.0011 | 0.0006 | 0.0016 | 0.0008 | 0.0036 | 0.0029 | 0.0113 | 0.0087 | 0.0506 | 0.0382 | 0.0872 | 0.0805 | 0.0734 | 0.0558 | 0.1058 | 0.0924 | 0.6654 | 0.7202 | 0.0018 | 0.0020 | 0.0026 | 0.0030 | 0.0084 | 0.0100 | 0.0221 | 0.0341 | 0.0767 | 0.0955 | 0.1270 | 0.1543 | 0.1088 | 0.1172 | 0.1486 | 0.1606 | 0.5040 | 0.4234 | 0.0007 | 0.0007 | 0.0050 | 0.0176 | 0.0665 | 0.0987 | 0.0932 | 0.1319 | 0.5858 | ||
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 431 | 339 | | 3943 | 10483 | 650.4 | 93.20 | 77.12 | 134.86 | 524 | 578 | 611 | 637 | 655 | 676 | 697 | 725 | 765 | 0.0630 | 660 | 1.066 | 99.30 | 32.65 | 1 | 0.0621 | 245 | 0.0013 | 29.21 | 6.926 | 0.2389 | 431670.0 | 292000000 | 201000000000 | 140000000000000 | 0.4337 | 0.2092 | 0.0006 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0043 | 0.0003 | 0.0239 | 0.0147 | 0.0347 | 0.0234 | 0.0340 | 0.0127 | 0.0534 | 0.0226 | 0.8476 | 0.9264 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0003 | 0.0148 | 0.0147 | 0.0235 | 0.0234 | 0.0179 | 0.0127 | 0.0277 | 0.0226 | 0.9140 | 0.9264 | 0.0065 | 0.0000 | 0.0065 | 0.0000 | 0.0226 | 0.0000 | 0.0355 | 0.0000 | 0.1000 | 0.0000 | 0.0871 | 0.0000 | 0.1065 | 0.0000 | 0.1290 | 0.0000 | 0.5065 | 0.0000 | 0.0000 | 0.0038 | 0.0072 | 0.0191 | 0.0401 | 0.0558 | 0.0615 | 0.0873 | 0.7252 | 6 | 8 | 9 | 11 | 14 | 22 | 53 | 125 | 238 | 0.1380 | 10.00 | 3.574 | 0.6077 | 24132.5 | 11700000 | 7110000000 | 4930000000000 | 0.4308 | 0.2239 | 0.0546 | 0.0060 | 0.1513 | 0.0313 | 0.2122 | 0.0625 | 0.1912 | 0.1159 | 0.1639 | 0.1915 | 0.1261 | 0.1935 | 0.0630 | 0.1381 | 0.0315 | 0.1190 | 0.0063 | 0.1421 | 0.0010 | 0.0000 | 0.0017 | 0.0015 | 0.0024 | 0.0033 | 0.0102 | 0.0118 | 0.0453 | 0.0386 | 0.0572 | 0.0477 | 0.0437 | 0.0443 | 0.0670 | 0.0641 | 0.7716 | 0.7887 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0020 | 0.0017 | 0.0113 | 0.0139 | 0.0577 | 0.0582 | 0.0658 | 0.0747 | 0.0516 | 0.0595 | 0.0791 | 0.0860 | 0.7313 | 0.7059 | 0.0004 | 0.0000 | 0.0015 | 0.0127 | 0.0470 | 0.0601 | 0.0548 | 0.0660 | 0.7576 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1202 | 629 | | 3328 | 8418 | 107.3 | 34.23 | 123.15 | 94.86 | 68 | 80 | 88 | 96 | 104 | 112 | 122 | 135 | 151 | 0.0986 | 830 | 0.231 | 169.10 | 42.20 | 3 | 0.2897 | 964 | 0.0010 | 62.39 | 7.144 | 0.1516 | 12681.7 | 1630000 | 227000000 | 34000000000 | 0.4848 | 0.1833 | 0.0006 | 0.0000 | 0.0062 | 0.0004 | 0.0296 | 0.0037 | 0.0889 | 0.0116 | 0.1705 | 0.0511 | 0.2341 | 0.1335 | 0.1692 | 0.1051 | 0.1316 | 0.1491 | 0.1692 | 0.5455 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0016 | 0.0003 | 0.0213 | 0.0046 | 0.0585 | 0.0354 | 0.1101 | 0.0827 | 0.0876 | 0.0423 | 0.1146 | 0.0813 | 0.6052 | 0.7534 | 0.0036 | 0.0109 | 0.0024 | 0.0163 | 0.0182 | 0.0245 | 0.0812 | 0.1226 | 0.1818 | 0.2670 | 0.1782 | 0.1853 | 0.1224 | 0.0981 | 0.1479 | 0.1390 | 0.2642 | 0.1362 | 0.0006 | 0.0006 | 0.0077 | 0.0379 | 0.1247 | 0.1433 | 0.1093 | 0.1549 | 0.4210 | 27 | 47 | 62 | 77 | 96 | 120 | 152 | 193 | 257 | 0.0090 | 14.86 | 5.556 | 0.4071 | 24163.0 | 6350000 | 2030000000 | 746000000000 | 0.5797 | 0.1151 | 0.0304 | 0.0016 | 0.1306 | 0.0066 | 0.2172 | 0.0487 | 0.1928 | 0.1050 | 0.1637 | 0.1644 | 0.1333 | 0.2011 | 0.0683 | 0.1502 | 0.0501 | 0.1416 | 0.0135 | 0.1808 | 0.0005 | 0.0008 | 0.0036 | 0.0010 | 0.0061 | 0.0053 | 0.0229 | 0.0187 | 0.0800 | 0.0542 | 0.1217 | 0.0941 | 0.1144 | 0.0875 | 0.1389 | 0.1205 | 0.5119 | 0.6179 | 0.0011 | 0.0034 | 0.0053 | 0.0116 | 0.0167 | 0.0198 | 0.0456 | 0.0545 | 0.1094 | 0.1369 | 0.1759 | 0.1803 | 0.1265 | 0.1345 | 0.1527 | 0.1572 | 0.3666 | 0.3018 | 0.0012 | 0.0055 | 0.0092 | 0.0348 | 0.0944 | 0.1521 | 0.1225 | 0.1512 | 0.4291 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 802 | 490 | | 8351 | 22610 | 575.7 | 122.92 | 67.00 | 140.53 | 447 | 481 | 507 | 530 | 554 | 578 | 610 | 654 | 726 | 0.0503 | 1138 | 0.892 | 99.02 | 25.02 | 1 | 0.0290 | 242 | 0.0006 | 85.09 | 7.659 | 0.1388 | 346489.0 | 219000000 | 147000000000 | 104000000000000 | 0.4366 | 0.2123 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0000 | 0.0107 | 0.0008 | 0.0464 | 0.0130 | 0.0968 | 0.0349 | 0.1084 | 0.0240 | 0.1476 | 0.0372 | 0.5879 | 0.8901 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0054 | 0.0000 | 0.0254 | 0.0090 | 0.0547 | 0.0192 | 0.0514 | 0.0107 | 0.0823 | 0.0199 | 0.7799 | 0.9412 | 0.0017 | 0.0022 | 0.0111 | 0.0066 | 0.0085 | 0.0087 | 0.0752 | 0.0502 | 0.1265 | 0.1397 | 0.1282 | 0.1790 | 0.0966 | 0.0830 | 0.1154 | 0.1397 | 0.4368 | 0.3908 | 0.0018 | 0.0062 | 0.0117 | 0.0486 | 0.0847 | 0.1260 | 0.0923 | 0.1116 | 0.5173 | 5 | 6 | 7 | 8 | 9 | 11 | 17 | 73 | 234 | 0.2107 | 10.92 | 3.086 | 0.6429 | 24238.2 | 13000000 | 8460000000 | 6260000000000 | 0.4231 | 0.2043 | 0.0750 | 0.0052 | 0.2339 | 0.0353 | 0.2519 | 0.1576 | 0.1589 | 0.1532 | 0.1364 | 0.2054 | 0.0885 | 0.1760 | 0.0390 | 0.1105 | 0.0150 | 0.0913 | 0.0015 | 0.0655 | 0.0000 | 0.0002 | 0.0004 | 0.0006 | 0.0016 | 0.0006 | 0.0084 | 0.0107 | 0.0408 | 0.0369 | 0.0753 | 0.0625 | 0.0404 | 0.0411 | 0.0677 | 0.0705 | 0.7654 | 0.7769 | 0.0002 | 0.0000 | 0.0009 | 0.0005 | 0.0016 | 0.0032 | 0.0125 | 0.0133 | 0.0519 | 0.0529 | 0.0775 | 0.0940 | 0.0542 | 0.0529 | 0.0860 | 0.0876 | 0.7152 | 0.6955 | 0.0002 | 0.0013 | 0.0024 | 0.0124 | 0.0425 | 0.0726 | 0.0494 | 0.0774 | 0.7419 |