High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 770 | 548 | | 4679 | 6669 | 137.8 | 37.32 | 193.13 | 136.78 | 97 | 107 | 115 | 123 | 132 | 140 | 151 | 165 | 188 | 0.1021 | 681 | 1.113 | 90.80 | 33.54 | 1 | 0.0524 | 245 | 0.0018 | 30.73 | 6.604 | 0.2167 | 20392.3 | 3250000 | 560000000 | 104000000000 | 0.4422 | 0.2057 | 0.0004 | 0.0000 | 0.0019 | 0.0000 | 0.0089 | 0.0007 | 0.0355 | 0.0024 | 0.1066 | 0.0257 | 0.1896 | 0.0591 | 0.1776 | 0.0651 | 0.1622 | 0.0905 | 0.3174 | 0.7565 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0043 | 0.0002 | 0.0097 | 0.0009 | 0.0441 | 0.0159 | 0.0819 | 0.0278 | 0.0802 | 0.0248 | 0.1044 | 0.0448 | 0.6745 | 0.8856 | 0.0054 | 0.0052 | 0.0086 | 0.0052 | 0.0119 | 0.0336 | 0.0627 | 0.1059 | 0.1568 | 0.2351 | 0.1859 | 0.2119 | 0.1092 | 0.0801 | 0.1557 | 0.1473 | 0.3038 | 0.1757 | 0.0015 | 0.0020 | 0.0085 | 0.0346 | 0.0989 | 0.1416 | 0.1145 | 0.1401 | 0.4583 | 42 | 70 | 97 | 128 | 161 | 203 | 250 | 305 | 391 | 0.0016 | 66.86 | 7.053 | 0.2296 | 56004.9 | 20500000 | 8680000000 | 4090000000000 | 0.5260 | 0.1564 | 0.0262 | 0.0016 | 0.1229 | 0.0056 | 0.2269 | 0.0334 | 0.1900 | 0.1091 | 0.1859 | 0.1851 | 0.1310 | 0.2201 | 0.0639 | 0.1584 | 0.0336 | 0.1421 | 0.0197 | 0.1445 | 0.0003 | 0.0007 | 0.0009 | 0.0007 | 0.0067 | 0.0024 | 0.0188 | 0.0163 | 0.0733 | 0.0544 | 0.1196 | 0.0928 | 0.0999 | 0.0728 | 0.1330 | 0.1079 | 0.5475 | 0.6521 | 0.0022 | 0.0017 | 0.0045 | 0.0063 | 0.0085 | 0.0150 | 0.0368 | 0.0600 | 0.1188 | 0.1298 | 0.1645 | 0.1997 | 0.1215 | 0.1298 | 0.1551 | 0.1558 | 0.3882 | 0.3018 | 0.0011 | 0.0032 | 0.0056 | 0.0275 | 0.0898 | 0.1479 | 0.1127 | 0.1437 | 0.4687 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1030 | 874 | | 3673 | 4603 | 174.5 | 51.15 | 215.89 | 185.55 | 121 | 134 | 145 | 155 | 165 | 176 | 189 | 208 | 237 | 0.1288 | 593 | 1.114 | 100.81 | 36.62 | 1 | 0.0719 | 264 | 0.0014 | 45.62 | 6.851 | 0.2136 | 33048.1 | 6890000 | 1610000000 | 426000000000 | 0.4339 | 0.2118 | 0.0005 | 0.0000 | 0.0029 | 0.0003 | 0.0103 | 0.0009 | 0.0275 | 0.0024 | 0.1035 | 0.0323 | 0.1844 | 0.0579 | 0.1540 | 0.0695 | 0.1923 | 0.1040 | 0.3247 | 0.7325 | 0.0004 | 0.0000 | 0.0011 | 0.0003 | 0.0054 | 0.0006 | 0.0098 | 0.0011 | 0.0493 | 0.0198 | 0.0761 | 0.0320 | 0.0692 | 0.0315 | 0.1036 | 0.0546 | 0.6853 | 0.8602 | 0.0042 | 0.0032 | 0.0083 | 0.0288 | 0.0208 | 0.0192 | 0.0554 | 0.1058 | 0.1302 | 0.1827 | 0.1911 | 0.1538 | 0.0817 | 0.1250 | 0.1440 | 0.1410 | 0.3643 | 0.2404 | 0.0033 | 0.0026 | 0.0131 | 0.0328 | 0.0858 | 0.1343 | 0.0878 | 0.1304 | 0.5098 | 21 | 49 | 86 | 127 | 170 | 218 | 276 | 353 | 485 | 0.0039 | 128.55 | 7.024 | 0.2296 | 81028.4 | 39900000 | 23100000000 | 14900000000000 | 0.4728 | 0.1730 | 0.0382 | 0.0006 | 0.1401 | 0.0110 | 0.2051 | 0.0760 | 0.1949 | 0.1098 | 0.1809 | 0.1696 | 0.1121 | 0.1982 | 0.0650 | 0.1404 | 0.0420 | 0.1261 | 0.0217 | 0.1683 | 0.0009 | 0.0004 | 0.0026 | 0.0011 | 0.0035 | 0.0044 | 0.0215 | 0.0139 | 0.0953 | 0.0645 | 0.1156 | 0.1004 | 0.0888 | 0.0751 | 0.1301 | 0.1084 | 0.5417 | 0.6319 | 0.0013 | 0.0042 | 0.0080 | 0.0059 | 0.0195 | 0.0210 | 0.0436 | 0.0470 | 0.1113 | 0.1293 | 0.1482 | 0.1839 | 0.1261 | 0.1167 | 0.1368 | 0.1310 | 0.4051 | 0.3610 | 0.0021 | 0.0016 | 0.0102 | 0.0376 | 0.0950 | 0.1432 | 0.1073 | 0.1266 | 0.4764 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 359 | 542 | | 4621 | 10762 | 146.2 | 33.43 | 222.69 | 177.49 | 107 | 118 | 125 | 134 | 142 | 151 | 161 | 172 | 191 | 0.0783 | 843 | 0.885 | 76.16 | 18.03 | 1 | 0.0390 | 180 | 0.0019 | 23.24 | 6.525 | 0.2373 | 22484.2 | 3640000 | 620000000 | 111000000000 | 0.4346 | 0.2115 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0058 | 0.0002 | 0.0194 | 0.0023 | 0.0890 | 0.0207 | 0.1549 | 0.0458 | 0.1876 | 0.0490 | 0.2146 | 0.0759 | 0.3279 | 0.8061 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0024 | 0.0002 | 0.0059 | 0.0009 | 0.0386 | 0.0147 | 0.0709 | 0.0249 | 0.0768 | 0.0190 | 0.1183 | 0.0332 | 0.6866 | 0.9071 | 0.0061 | 0.0150 | 0.0207 | 0.0187 | 0.0292 | 0.0487 | 0.0901 | 0.1423 | 0.1681 | 0.1723 | 0.1791 | 0.2247 | 0.1108 | 0.1086 | 0.1462 | 0.1236 | 0.2497 | 0.1461 | 0.0009 | 0.0043 | 0.0080 | 0.0326 | 0.0913 | 0.1456 | 0.1210 | 0.1504 | 0.4459 | 44 | 73 | 105 | 144 | 183 | 226 | 275 | 342 | 445 | 0.0015 | 74.52 | 7.246 | 0.2302 | 81090.3 | 40900000 | 26000000000 | 19500000000000 | 0.4630 | 0.1957 | 0.0142 | 0.0014 | 0.0752 | 0.0062 | 0.1565 | 0.0283 | 0.1896 | 0.0627 | 0.1844 | 0.1479 | 0.1697 | 0.2060 | 0.1092 | 0.1512 | 0.0700 | 0.1579 | 0.0312 | 0.2384 | 0.0009 | 0.0003 | 0.0020 | 0.0012 | 0.0062 | 0.0036 | 0.0222 | 0.0121 | 0.0621 | 0.0464 | 0.1076 | 0.0967 | 0.0994 | 0.0695 | 0.1261 | 0.1058 | 0.5735 | 0.6645 | 0.0015 | 0.0019 | 0.0047 | 0.0070 | 0.0174 | 0.0174 | 0.0375 | 0.0557 | 0.0962 | 0.1161 | 0.1535 | 0.1663 | 0.1125 | 0.1199 | 0.1367 | 0.1389 | 0.4401 | 0.3768 | 0.0007 | 0.0043 | 0.0107 | 0.0285 | 0.0859 | 0.1281 | 0.1071 | 0.1381 | 0.4965 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 122 | 891 | | 5327 | 11696 | 148.0 | 43.59 | 217.70 | 199.22 | 99 | 112 | 123 | 132 | 142 | 151 | 163 | 179 | 203 | 0.0892 | 1043 | 1.215 | 95.34 | 38.64 | 1 | 0.0466 | 248 | 0.0014 | 41.30 | 6.881 | 0.2047 | 23789.2 | 4180000 | 807000000 | 172000000000 | 0.4266 | 0.2289 | 0.0000 | 0.0000 | 0.0056 | 0.0000 | 0.0251 | 0.0013 | 0.0471 | 0.0047 | 0.1157 | 0.0325 | 0.1666 | 0.0629 | 0.1649 | 0.0713 | 0.1997 | 0.1120 | 0.2754 | 0.7151 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0038 | 0.0006 | 0.0121 | 0.0008 | 0.0476 | 0.0188 | 0.0784 | 0.0323 | 0.0758 | 0.0298 | 0.1162 | 0.0531 | 0.6657 | 0.8647 | 0.0082 | 0.0150 | 0.0082 | 0.0107 | 0.0245 | 0.0515 | 0.0927 | 0.1180 | 0.1455 | 0.1888 | 0.1936 | 0.1996 | 0.1264 | 0.1245 | 0.1564 | 0.1352 | 0.2445 | 0.1567 | 0.0017 | 0.0038 | 0.0137 | 0.0384 | 0.0970 | 0.1482 | 0.1179 | 0.1521 | 0.4272 | 20 | 42 | 72 | 110 | 157 | 216 | 283 | 375 | 516 | 0.0025 | 101.46 | 7.379 | 0.2318 | 87079.5 | 45700000 | 28000000000 | 19200000000000 | 0.4833 | 0.1693 | 0.0350 | 0.0024 | 0.1038 | 0.0141 | 0.1931 | 0.0587 | 0.1431 | 0.1069 | 0.1600 | 0.1598 | 0.1213 | 0.1625 | 0.1000 | 0.1305 | 0.0781 | 0.1354 | 0.0656 | 0.2298 | 0.0009 | 0.0005 | 0.0017 | 0.0025 | 0.0061 | 0.0045 | 0.0160 | 0.0176 | 0.0575 | 0.0550 | 0.0955 | 0.0812 | 0.0699 | 0.0655 | 0.1043 | 0.0953 | 0.6482 | 0.6780 | 0.0013 | 0.0012 | 0.0039 | 0.0053 | 0.0078 | 0.0112 | 0.0234 | 0.0287 | 0.0793 | 0.0765 | 0.1139 | 0.1255 | 0.0886 | 0.0921 | 0.1219 | 0.1240 | 0.5599 | 0.5353 | 0.0011 | 0.0013 | 0.0071 | 0.0174 | 0.0656 | 0.1025 | 0.0861 | 0.1177 | 0.6012 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 659 | 414 | | 3454 | 6251 | 174.4 | 39.87 | 242.89 | 154.32 | 131 | 143 | 152 | 159 | 167 | 177 | 189 | 204 | 226 | 0.1125 | 703 | 1.107 | 91.24 | 26.63 | 1 | 0.0617 | 213 | 0.0019 | 25.62 | 6.561 | 0.2385 | 32018.5 | 6210000 | 1280000000 | 278000000000 | 0.4520 | 0.2052 | 0.0004 | 0.0000 | 0.0009 | 0.0003 | 0.0088 | 0.0006 | 0.0206 | 0.0022 | 0.0697 | 0.0235 | 0.1434 | 0.0423 | 0.1298 | 0.0346 | 0.1684 | 0.0676 | 0.4579 | 0.8289 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0003 | 0.0052 | 0.0003 | 0.0351 | 0.0160 | 0.0762 | 0.0274 | 0.0616 | 0.0189 | 0.1043 | 0.0335 | 0.7155 | 0.9036 | 0.0017 | 0.0154 | 0.0134 | 0.0205 | 0.0185 | 0.0308 | 0.0487 | 0.1026 | 0.1546 | 0.1231 | 0.1748 | 0.1846 | 0.1294 | 0.1538 | 0.1429 | 0.0923 | 0.3160 | 0.2769 | 0.0007 | 0.0033 | 0.0080 | 0.0361 | 0.0916 | 0.1424 | 0.0989 | 0.1404 | 0.4786 | 79 | 111 | 142 | 170 | 206 | 251 | 299 | 360 | 457 | 0.0013 | 68.96 | 7.135 | 0.2323 | 82803.2 | 35900000 | 18500000000 | 10900000000000 | 0.5283 | 0.1292 | 0.0088 | 0.0007 | 0.0739 | 0.0045 | 0.1684 | 0.0182 | 0.1611 | 0.0636 | 0.1859 | 0.1374 | 0.1720 | 0.2049 | 0.1061 | 0.1528 | 0.0820 | 0.1545 | 0.0417 | 0.2633 | 0.0003 | 0.0002 | 0.0027 | 0.0005 | 0.0066 | 0.0040 | 0.0217 | 0.0160 | 0.0714 | 0.0488 | 0.1042 | 0.0905 | 0.0819 | 0.0726 | 0.1153 | 0.1014 | 0.5959 | 0.6660 | 0.0041 | 0.0042 | 0.0051 | 0.0035 | 0.0128 | 0.0229 | 0.0389 | 0.0660 | 0.1064 | 0.1313 | 0.1529 | 0.1771 | 0.1233 | 0.1188 | 0.1483 | 0.1465 | 0.4082 | 0.3299 | 0.0004 | 0.0031 | 0.0100 | 0.0268 | 0.0824 | 0.1234 | 0.1031 | 0.1388 | 0.5121 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1075 | 895 | | 4118 | 4934 | 145.3 | 36.15 | 206.60 | 178.21 | 103 | 116 | 125 | 133 | 141 | 149 | 158 | 171 | 192 | 0.1336 | 659 | 0.978 | 89.59 | 26.42 | 1 | 0.0529 | 218 | 0.0019 | 27.36 | 6.598 | 0.2315 | 22405.4 | 3670000 | 641000000 | 119000000000 | 0.4147 | 0.2407 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0093 | 0.0003 | 0.0201 | 0.0030 | 0.0872 | 0.0280 | 0.1515 | 0.0560 | 0.1519 | 0.0633 | 0.1709 | 0.0810 | 0.4076 | 0.7684 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0000 | 0.0060 | 0.0007 | 0.0400 | 0.0177 | 0.0771 | 0.0337 | 0.0689 | 0.0327 | 0.0915 | 0.0434 | 0.7140 | 0.8718 | 0.0013 | 0.0068 | 0.0067 | 0.0136 | 0.0324 | 0.0306 | 0.0931 | 0.1054 | 0.1242 | 0.1667 | 0.1768 | 0.1939 | 0.1188 | 0.1224 | 0.1174 | 0.1361 | 0.3293 | 0.2245 | 0.0005 | 0.0037 | 0.0095 | 0.0349 | 0.1138 | 0.1376 | 0.1027 | 0.1466 | 0.4505 | 24 | 53 | 88 | 122 | 160 | 204 | 256 | 333 | 460 | 0.0021 | 74.59 | 7.103 | 0.2341 | 74435.4 | 36000000 | 21000000000 | 13800000000000 | 0.4404 | 0.2138 | 0.0141 | 0.0018 | 0.0633 | 0.0084 | 0.1547 | 0.0349 | 0.1864 | 0.0699 | 0.1934 | 0.1470 | 0.1536 | 0.1946 | 0.1313 | 0.1524 | 0.0610 | 0.1837 | 0.0422 | 0.2072 | 0.0012 | 0.0003 | 0.0033 | 0.0024 | 0.0067 | 0.0058 | 0.0158 | 0.0151 | 0.0596 | 0.0599 | 0.0979 | 0.0767 | 0.0870 | 0.0712 | 0.1083 | 0.1070 | 0.6202 | 0.6615 | 0.0013 | 0.0024 | 0.0071 | 0.0040 | 0.0110 | 0.0176 | 0.0323 | 0.0353 | 0.0788 | 0.0842 | 0.1072 | 0.1259 | 0.0969 | 0.0874 | 0.1111 | 0.1115 | 0.5543 | 0.5317 | 0.0026 | 0.0026 | 0.0067 | 0.0231 | 0.0817 | 0.0966 | 0.0910 | 0.1182 | 0.5776 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1098 | 245 | | 11985 | 25048 | 84.9 | 24.68 | 210.46 | 174.39 | 57 | 66 | 72 | 78 | 83 | 89 | 96 | 104 | 117 | 0.0493 | 1235 | 1.212 | 170.77 | 60.46 | 3 | 0.0339 | 406 | 0.0035 | 11.99 | 6.022 | 0.3238 | 7822.1 | 773291 | 81600000 | 9180000000 | 0.4646 | 0.2016 | 0.0015 | 0.0001 | 0.0035 | 0.0002 | 0.0189 | 0.0013 | 0.0497 | 0.0060 | 0.0986 | 0.0268 | 0.1577 | 0.0599 | 0.1701 | 0.0693 | 0.1916 | 0.1035 | 0.3083 | 0.7329 | 0.0005 | 0.0000 | 0.0011 | 0.0001 | 0.0039 | 0.0001 | 0.0150 | 0.0019 | 0.0339 | 0.0136 | 0.0662 | 0.0303 | 0.0676 | 0.0255 | 0.0968 | 0.0435 | 0.7150 | 0.8851 | 0.0033 | 0.0121 | 0.0080 | 0.0260 | 0.0256 | 0.0419 | 0.0756 | 0.1200 | 0.1388 | 0.1842 | 0.1465 | 0.1777 | 0.1385 | 0.1284 | 0.1600 | 0.1265 | 0.3036 | 0.1833 | 0.0009 | 0.0050 | 0.0135 | 0.0414 | 0.0740 | 0.1119 | 0.1069 | 0.1367 | 0.5097 | 27 | 50 | 85 | 129 | 174 | 220 | 274 | 342 | 444 | 0.0030 | 74.43 | 7.191 | 0.2347 | 74701.9 | 35300000 | 20500000000 | 14000000000000 | 0.4914 | 0.1942 | 0.0341 | 0.0005 | 0.1480 | 0.0067 | 0.2568 | 0.0741 | 0.1712 | 0.1263 | 0.1455 | 0.1772 | 0.1169 | 0.1937 | 0.0654 | 0.1449 | 0.0389 | 0.1300 | 0.0232 | 0.1465 | 0.0003 | 0.0001 | 0.0016 | 0.0005 | 0.0037 | 0.0012 | 0.0153 | 0.0094 | 0.0721 | 0.0542 | 0.1302 | 0.1070 | 0.0998 | 0.0805 | 0.1378 | 0.1181 | 0.5392 | 0.6290 | 0.0009 | 0.0021 | 0.0040 | 0.0065 | 0.0122 | 0.0178 | 0.0377 | 0.0512 | 0.1055 | 0.1206 | 0.1719 | 0.1793 | 0.1135 | 0.1149 | 0.1437 | 0.1477 | 0.4105 | 0.3599 | 0.0007 | 0.0020 | 0.0080 | 0.0239 | 0.0873 | 0.1563 | 0.1162 | 0.1382 | 0.4675 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 613 | 713 | | 713 | 1229 | 91.3 | 14.01 | 6.39 | 2.54 | 72 | 77 | 83 | 87 | 92 | 96 | 100 | 104 | 109 | 0.2522 | 310 | 1.070 | 24.52 | 7.28 | 1 | 0.0884 | 63 | 0.0680 | 0.69 | 2.897 | 0.7227 | 8522.9 | 813628 | 79300000 | 7870000000 | 0.3848 | 0.2534 | 0.0000 | 0.0000 | 0.0053 | 0.0000 | 0.0123 | 0.0014 | 0.0247 | 0.0014 | 0.0670 | 0.0492 | 0.0917 | 0.0646 | 0.1217 | 0.0478 | 0.1711 | 0.0772 | 0.5062 | 0.7584 | 0.0000 | 0.0000 | 0.0048 | 0.0000 | 0.0095 | 0.0014 | 0.0127 | 0.0014 | 0.0523 | 0.0491 | 0.0507 | 0.0645 | 0.0555 | 0.0477 | 0.0777 | 0.0659 | 0.7369 | 0.7700 | 0.0156 | 1.0000 | 0.0938 | 0.0000 | 0.0625 | 0.0000 | 0.1406 | 0.0000 | 0.2344 | 0.0000 | 0.1875 | 0.0000 | 0.0781 | 0.0000 | 0.1094 | 0.0000 | 0.0781 | 0.0000 | 0.0053 | 0.0107 | 0.0213 | 0.0373 | 0.0613 | 0.0587 | 0.0827 | 0.1280 | 0.5947 | 3 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0448 | 0.26 | 0.778 | 0.2347 | 47.3 | 411.762 | 4361.59 | 56996.9 | 0.5177 | 0.1432 | 0.0094 | 0.0021 | 0.0336 | 0.0064 | 0.0983 | 0.0364 | 0.1023 | 0.0621 | 0.1911 | 0.1424 | 0.2248 | 0.1681 | 0.1736 | 0.2141 | 0.1279 | 0.2473 | 0.0390 | 0.1210 | 0.0000 | 0.0000 | 0.0048 | 0.0009 | 0.0183 | 0.0109 | 0.0502 | 0.0263 | 0.1187 | 0.1069 | 0.1525 | 0.1295 | 0.2008 | 0.1639 | 0.2346 | 0.2473 | 0.2201 | 0.3143 | 0.1365 | 0.2588 | 0.2048 | 0.1882 | 0.1468 | 0.1353 | 0.1433 | 0.1353 | 0.1502 | 0.0588 | 0.0785 | 0.0471 | 0.0512 | 0.0529 | 0.0375 | 0.0412 | 0.0512 | 0.0824 | 0.0038 | 0.0368 | 0.0722 | 0.1293 | 0.1812 | 0.1787 | 0.1496 | 0.1546 | 0.0938 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1173 | 230 | | 893 | 1587 | 58.0 | 13.43 | 491.67 | 350.26 | 39 | 45 | 50 | 54 | 59 | 63 | 67 | 71 | 75 | 0.1878 | 298 | 1.216 | 22.85 | 8.25 | 1 | 0.0694 | 62 | 0.0063 | 5.77 | 5.275 | 0.3973 | 3548.7 | 226676 | 15000000 | 1020000000 | 0.4245 | 0.2042 | 0.0041 | 0.0000 | 0.0104 | 0.0000 | 0.0228 | 0.0012 | 0.0352 | 0.0119 | 0.1056 | 0.0380 | 0.1201 | 0.0403 | 0.1677 | 0.0712 | 0.1822 | 0.0830 | 0.3520 | 0.7544 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0058 | 0.0012 | 0.0159 | 0.0116 | 0.0418 | 0.0359 | 0.0390 | 0.0348 | 0.0592 | 0.0475 | 0.0649 | 0.0487 | 0.7706 | 0.8204 | 0.0095 | 0.0500 | 0.0143 | 0.1000 | 0.0190 | 0.0500 | 0.0476 | 0.2000 | 0.1381 | 0.3000 | 0.1095 | 0.1000 | 0.1810 | 0.0000 | 0.1905 | 0.2000 | 0.2905 | 0.0000 | 0.0043 | 0.0151 | 0.0151 | 0.0129 | 0.0430 | 0.0688 | 0.0860 | 0.1011 | 0.6538 | 107 | 162 | 233 | 315 | 418 | 517 | 636 | 803 | 998 | 0.0021 | 39.34 | 6.548 | 0.2363 | 364349.0 | 335000000 | 350000000000 | 398000000000000 | 0.5161 | 0.1411 | 0.0070 | 0.0000 | 0.0702 | 0.0035 | 0.1579 | 0.0228 | 0.2316 | 0.0683 | 0.2140 | 0.1278 | 0.1789 | 0.2277 | 0.0877 | 0.1611 | 0.0386 | 0.1664 | 0.0140 | 0.2224 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0061 | 0.0020 | 0.0255 | 0.0201 | 0.0522 | 0.0413 | 0.0765 | 0.0554 | 0.0667 | 0.0564 | 0.1129 | 0.0816 | 0.6590 | 0.7432 | 0.0019 | 0.0000 | 0.0000 | 0.0047 | 0.0111 | 0.0213 | 0.0390 | 0.0332 | 0.0686 | 0.0900 | 0.1317 | 0.1232 | 0.0891 | 0.0853 | 0.1132 | 0.1422 | 0.5455 | 0.5000 | 0.0000 | 0.0059 | 0.0089 | 0.0341 | 0.0548 | 0.0904 | 0.0919 | 0.1407 | 0.5733 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 129 | 102 | | 853 | 4631 | 107.8 | 32.30 | 12.53 | 4.15 | 72 | 80 | 87 | 94 | 102 | 110 | 119 | 135 | 159 | 0.1162 | 538 | 1.081 | 46.87 | 17.49 | 1 | 0.1489 | 127 | 0.0142 | 2.79 | 4.517 | 0.4969 | 12655.4 | 1610000 | 221000000 | 32300000000 | 0.4358 | 0.2021 | 0.0024 | 0.0000 | 0.0024 | 0.0028 | 0.0097 | 0.0014 | 0.0607 | 0.0185 | 0.1602 | 0.0541 | 0.1990 | 0.1223 | 0.1553 | 0.0896 | 0.1456 | 0.1181 | 0.2646 | 0.5932 | 0.0017 | 0.0000 | 0.0017 | 0.0012 | 0.0066 | 0.0000 | 0.0249 | 0.0111 | 0.0731 | 0.0382 | 0.0897 | 0.0764 | 0.0797 | 0.0480 | 0.1030 | 0.0640 | 0.6196 | 0.7611 | 0.0000 | 0.0000 | 0.0105 | 0.0000 | 0.0105 | 0.0092 | 0.0316 | 0.0734 | 0.0947 | 0.1376 | 0.1211 | 0.1835 | 0.0789 | 0.1193 | 0.1421 | 0.1835 | 0.5105 | 0.2936 | 0.0055 | 0.0055 | 0.0110 | 0.0440 | 0.0769 | 0.1044 | 0.1181 | 0.1209 | 0.5137 | 7 | 9 | 10 | 11 | 12 | 13 | 14 | 16 | 18 | 0.0078 | 26.38 | 5.307 | 0.2385 | 174.1 | 2649.31 | 43748.6 | 779909 | 0.5184 | 0.1395 | 0.0240 | 0.0003 | 0.0831 | 0.0035 | 0.1717 | 0.0122 | 0.2432 | 0.0319 | 0.2538 | 0.0856 | 0.1461 | 0.1297 | 0.0621 | 0.2158 | 0.0130 | 0.3053 | 0.0030 | 0.2158 | 0.0040 | 0.0000 | 0.0242 | 0.0010 | 0.0646 | 0.0043 | 0.1036 | 0.0183 | 0.1480 | 0.0550 | 0.1705 | 0.0815 | 0.1609 | 0.1399 | 0.1487 | 0.2628 | 0.1755 | 0.4372 | 0.1595 | 0.2552 | 0.1673 | 0.1849 | 0.1399 | 0.1094 | 0.1145 | 0.1484 | 0.1243 | 0.1198 | 0.0920 | 0.0964 | 0.0841 | 0.0495 | 0.0626 | 0.0339 | 0.0558 | 0.0026 | 0.0301 | 0.0872 | 0.1248 | 0.1442 | 0.1442 | 0.1368 | 0.1113 | 0.1076 | 0.1136 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 469 | 396 | | 3985 | 3374 | 160.1 | 46.65 | 190.25 | 141.76 | 107 | 121 | 132 | 142 | 153 | 165 | 177 | 195 | 221 | 0.2110 | 712 | 0.988 | 83.24 | 28.02 | 1 | 0.0575 | 229 | 0.0012 | 50.08 | 6.991 | 0.1783 | 27806.5 | 5240000 | 1070000000 | 235000000000 | 0.4379 | 0.2135 | 0.0010 | 0.0000 | 0.0005 | 0.0000 | 0.0144 | 0.0017 | 0.0460 | 0.0032 | 0.1321 | 0.0326 | 0.1991 | 0.0843 | 0.1709 | 0.0837 | 0.1728 | 0.1160 | 0.2633 | 0.6784 | 0.0007 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0003 | 0.0098 | 0.0016 | 0.0480 | 0.0199 | 0.0912 | 0.0482 | 0.0784 | 0.0364 | 0.0966 | 0.0566 | 0.6743 | 0.8371 | 0.0069 | 0.0079 | 0.0023 | 0.0237 | 0.0230 | 0.0211 | 0.0746 | 0.0868 | 0.1389 | 0.2237 | 0.1929 | 0.2053 | 0.1114 | 0.0974 | 0.1389 | 0.1316 | 0.3111 | 0.2026 | 0.0017 | 0.0017 | 0.0067 | 0.0274 | 0.1016 | 0.1496 | 0.1111 | 0.1407 | 0.4595 | 58 | 75 | 93 | 117 | 144 | 179 | 227 | 297 | 404 | 0.0022 | 69.15 | 6.693 | 0.2400 | 56286.8 | 22200000 | 10500000000 | 5560000000000 | 0.5618 | 0.1030 | 0.0253 | 0.0040 | 0.1149 | 0.0127 | 0.2821 | 0.0573 | 0.1909 | 0.1131 | 0.1740 | 0.1863 | 0.1166 | 0.2126 | 0.0439 | 0.1242 | 0.0389 | 0.1449 | 0.0135 | 0.1449 | 0.0006 | 0.0019 | 0.0025 | 0.0029 | 0.0125 | 0.0058 | 0.0368 | 0.0277 | 0.1085 | 0.0893 | 0.1696 | 0.1422 | 0.1103 | 0.1053 | 0.1490 | 0.1465 | 0.4102 | 0.4784 | 0.0049 | 0.0037 | 0.0069 | 0.0075 | 0.0208 | 0.0298 | 0.0573 | 0.0658 | 0.1285 | 0.1466 | 0.1887 | 0.1814 | 0.1176 | 0.1379 | 0.1542 | 0.1466 | 0.3211 | 0.2807 | 0.0016 | 0.0071 | 0.0158 | 0.0434 | 0.1278 | 0.1838 | 0.1112 | 0.1546 | 0.3549 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 283 | 97 | | 3964 | 10522 | 352.2 | 81.30 | 461.34 | 382.37 | 252 | 288 | 313 | 334 | 354 | 372 | 392 | 416 | 452 | 0.0657 | 691 | 0.753 | 95.27 | 24.08 | 1 | 0.0658 | 261 | 0.0006 | 102.74 | 7.612 | 0.1258 | 130633.0 | 50600000 | 20400000000 | 8530000000000 | 0.4023 | 0.2386 | 0.0008 | 0.0000 | 0.0008 | 0.0000 | 0.0043 | 0.0000 | 0.0179 | 0.0014 | 0.0550 | 0.0209 | 0.1072 | 0.0390 | 0.1228 | 0.0329 | 0.1454 | 0.0549 | 0.5458 | 0.8510 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0061 | 0.0013 | 0.0223 | 0.0154 | 0.0444 | 0.0260 | 0.0471 | 0.0172 | 0.0640 | 0.0262 | 0.8145 | 0.9139 | 0.0000 | 0.0109 | 0.0100 | 0.0109 | 0.0242 | 0.0217 | 0.0627 | 0.1033 | 0.1296 | 0.1467 | 0.1553 | 0.1413 | 0.1254 | 0.1196 | 0.1538 | 0.1033 | 0.3390 | 0.3424 | 0.0010 | 0.0035 | 0.0049 | 0.0233 | 0.0673 | 0.1054 | 0.1049 | 0.1242 | 0.5656 | 46 | 92 | 175 | 276 | 376 | 494 | 622 | 777 | 1000 | 0.0020 | 93.98 | 7.546 | 0.2428 | 359026.0 | 355000000 | 407000000000 | 521000000000000 | 0.5626 | 0.1363 | 0.0068 | 0.0015 | 0.0542 | 0.0057 | 0.1423 | 0.0121 | 0.1725 | 0.0508 | 0.1725 | 0.1309 | 0.1744 | 0.1967 | 0.1072 | 0.1517 | 0.0930 | 0.1565 | 0.0770 | 0.2940 | 0.0004 | 0.0000 | 0.0039 | 0.0011 | 0.0049 | 0.0030 | 0.0161 | 0.0105 | 0.0447 | 0.0377 | 0.0709 | 0.0692 | 0.0629 | 0.0510 | 0.0765 | 0.0729 | 0.7196 | 0.7546 | 0.0008 | 0.0007 | 0.0027 | 0.0023 | 0.0065 | 0.0073 | 0.0220 | 0.0293 | 0.0578 | 0.0676 | 0.0957 | 0.1119 | 0.0774 | 0.0916 | 0.1013 | 0.1196 | 0.6358 | 0.5696 | 0.0002 | 0.0022 | 0.0038 | 0.0146 | 0.0510 | 0.0864 | 0.0649 | 0.0858 | 0.6910 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1022 | 692 | | 3454 | 3530 | 167.4 | 41.65 | 180.50 | 117.23 | 122 | 134 | 143 | 152 | 160 | 170 | 182 | 197 | 221 | 0.1552 | 548 | 0.994 | 92.70 | 30.02 | 1 | 0.0753 | 260 | 0.0018 | 25.32 | 6.610 | 0.2337 | 29750.6 | 5640000 | 1140000000 | 247000000000 | 0.4167 | 0.2267 | 0.0019 | 0.0000 | 0.0014 | 0.0000 | 0.0079 | 0.0019 | 0.0200 | 0.0045 | 0.0723 | 0.0243 | 0.1361 | 0.0530 | 0.1441 | 0.0501 | 0.1716 | 0.0728 | 0.4448 | 0.7935 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0033 | 0.0000 | 0.0094 | 0.0012 | 0.0333 | 0.0171 | 0.0716 | 0.0339 | 0.0651 | 0.0233 | 0.0763 | 0.0369 | 0.7401 | 0.8876 | 0.0048 | 0.0078 | 0.0032 | 0.0078 | 0.0193 | 0.0273 | 0.0612 | 0.0898 | 0.1433 | 0.1406 | 0.1578 | 0.2031 | 0.1111 | 0.0898 | 0.1481 | 0.1680 | 0.3510 | 0.2656 | 0.0027 | 0.0040 | 0.0121 | 0.0336 | 0.0666 | 0.1217 | 0.0941 | 0.1163 | 0.5488 | 51 | 75 | 99 | 126 | 155 | 189 | 229 | 282 | 342 | 0.0019 | 49.51 | 6.719 | 0.2474 | 46319.3 | 14800000 | 5500000000 | 2270000000000 | 0.4820 | 0.1669 | 0.0110 | 0.0014 | 0.0992 | 0.0081 | 0.1983 | 0.0359 | 0.1832 | 0.0670 | 0.1749 | 0.1475 | 0.1405 | 0.2023 | 0.0992 | 0.1387 | 0.0702 | 0.1732 | 0.0234 | 0.2260 | 0.0011 | 0.0004 | 0.0032 | 0.0013 | 0.0053 | 0.0038 | 0.0185 | 0.0162 | 0.0678 | 0.0489 | 0.1070 | 0.0919 | 0.0970 | 0.0655 | 0.1436 | 0.1123 | 0.5564 | 0.6597 | 0.0017 | 0.0000 | 0.0078 | 0.0103 | 0.0138 | 0.0126 | 0.0491 | 0.0515 | 0.0956 | 0.1214 | 0.1731 | 0.1901 | 0.1051 | 0.1420 | 0.1447 | 0.1741 | 0.4091 | 0.2978 | 0.0013 | 0.0040 | 0.0047 | 0.0330 | 0.0982 | 0.1365 | 0.1063 | 0.1466 | 0.4694 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 559 | 386 | | 734 | 10113 | 39.1 | 16.71 | 545.35 | 386.84 | 28 | 29 | 30 | 31 | 32 | 34 | 37 | 45 | 64 | 0.0518 | 524 | 0.593 | 209.07 | 60.01 | 2 | 0.9973 | 732 | 0.0308 | 4.90 | 4.259 | 0.5054 | 1809.2 | 103002 | 7120000 | 567000000 | 0.4029 | 0.2328 | 0.0252 | 0.0000 | 0.0540 | 0.0000 | 0.0755 | 0.0000 | 0.1295 | 0.0174 | 0.1403 | 0.0616 | 0.1799 | 0.0585 | 0.1403 | 0.0932 | 0.1475 | 0.0853 | 0.1079 | 0.6840 | 0.0170 | 0.0000 | 0.0365 | 0.0000 | 0.0462 | 0.0000 | 0.0754 | 0.0136 | 0.0730 | 0.0409 | 0.0900 | 0.0368 | 0.0681 | 0.0587 | 0.1095 | 0.0559 | 0.4842 | 0.7940 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0376 | 0.0200 | 0.0752 | 0.1500 | 0.0827 | 0.0400 | 0.0977 | 0.1100 | 0.0752 | 0.1200 | 0.6316 | 0.5600 | 0.0000 | 0.0052 | 0.0103 | 0.0155 | 0.0619 | 0.0825 | 0.0825 | 0.0928 | 0.6495 | 110 | 186 | 267 | 361 | 473 | 591 | 720 | 874 | 1078 | 0.0014 | 42.72 | 7.230 | 0.2482 | 447031.0 | 456000000 | 536000000000 | 698000000000000 | 0.4409 | 0.2151 | 0.0049 | 0.0008 | 0.0213 | 0.0030 | 0.1079 | 0.0134 | 0.1706 | 0.0422 | 0.2262 | 0.1218 | 0.2011 | 0.1874 | 0.1226 | 0.1487 | 0.0823 | 0.1769 | 0.0632 | 0.3059 | 0.0004 | 0.0003 | 0.0013 | 0.0006 | 0.0037 | 0.0034 | 0.0144 | 0.0101 | 0.0397 | 0.0346 | 0.0744 | 0.0570 | 0.0498 | 0.0461 | 0.0699 | 0.0684 | 0.7464 | 0.7795 | 0.0017 | 0.0015 | 0.0017 | 0.0015 | 0.0043 | 0.0070 | 0.0218 | 0.0278 | 0.0519 | 0.0725 | 0.0930 | 0.1147 | 0.0904 | 0.1118 | 0.1106 | 0.1336 | 0.6246 | 0.5296 | 0.0007 | 0.0052 | 0.0059 | 0.0197 | 0.0437 | 0.0749 | 0.0656 | 0.0837 | 0.7007 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 640 | 505 | | 7321 | 15664 | 132.9 | 24.36 | 203.28 | 114.00 | 103 | 113 | 120 | 126 | 131 | 137 | 144 | 152 | 164 | 0.0602 | 943 | 0.886 | 94.20 | 24.52 | 1 | 0.0328 | 240 | 0.0034 | 11.56 | 6.014 | 0.3124 | 18256.5 | 2590000 | 379000000 | 57200000000 | 0.4249 | 0.2269 | 0.0000 | 0.0001 | 0.0000 | 0.0000 | 0.0031 | 0.0001 | 0.0107 | 0.0008 | 0.0451 | 0.0126 | 0.0959 | 0.0291 | 0.1106 | 0.0302 | 0.1519 | 0.0455 | 0.5827 | 0.8815 | 0.0000 | 0.0001 | 0.0000 | 0.0000 | 0.0013 | 0.0001 | 0.0041 | 0.0006 | 0.0213 | 0.0113 | 0.0421 | 0.0206 | 0.0458 | 0.0151 | 0.0696 | 0.0214 | 0.8160 | 0.9308 | 0.0083 | 0.0311 | 0.0156 | 0.0497 | 0.0353 | 0.0807 | 0.1048 | 0.1491 | 0.1566 | 0.2609 | 0.1940 | 0.1677 | 0.1193 | 0.0621 | 0.1421 | 0.1429 | 0.2241 | 0.0559 | 0.0026 | 0.0048 | 0.0145 | 0.0318 | 0.0705 | 0.1166 | 0.1066 | 0.1362 | 0.5163 | 66 | 100 | 130 | 159 | 188 | 221 | 256 | 298 | 361 | 0.0013 | 36.57 | 7.039 | 0.2500 | 54319.8 | 17300000 | 6280000000 | 2520000000000 | 0.5417 | 0.1374 | 0.0116 | 0.0006 | 0.0610 | 0.0034 | 0.1692 | 0.0206 | 0.1815 | 0.0547 | 0.2027 | 0.1259 | 0.1727 | 0.1917 | 0.1056 | 0.1593 | 0.0625 | 0.1770 | 0.0330 | 0.2666 | 0.0005 | 0.0002 | 0.0016 | 0.0004 | 0.0064 | 0.0030 | 0.0191 | 0.0101 | 0.0584 | 0.0425 | 0.1194 | 0.0871 | 0.0931 | 0.0697 | 0.1203 | 0.1000 | 0.5810 | 0.6870 | 0.0025 | 0.0036 | 0.0078 | 0.0101 | 0.0228 | 0.0258 | 0.0457 | 0.0697 | 0.1071 | 0.1403 | 0.1660 | 0.1930 | 0.1333 | 0.1409 | 0.1465 | 0.1479 | 0.3682 | 0.2686 | 0.0013 | 0.0039 | 0.0104 | 0.0303 | 0.0787 | 0.1477 | 0.1131 | 0.1412 | 0.4735 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 224 | 158 | | 4015 | 9039 | 129.9 | 42.42 | 240.53 | 197.92 | 83 | 93 | 102 | 112 | 122 | 132 | 145 | 164 | 192 | 0.0824 | 745 | 0.608 | 137.06 | 32.56 | 2 | 0.0914 | 367 | 0.0017 | 32.79 | 6.720 | 0.2241 | 18668.6 | 2960000 | 512000000 | 95700000000 | 0.4366 | 0.2129 | 0.0006 | 0.0000 | 0.0083 | 0.0000 | 0.0286 | 0.0025 | 0.0787 | 0.0136 | 0.1398 | 0.0414 | 0.1937 | 0.0891 | 0.1717 | 0.0999 | 0.1805 | 0.1349 | 0.1981 | 0.6186 | 0.0004 | 0.0000 | 0.0029 | 0.0000 | 0.0065 | 0.0003 | 0.0199 | 0.0051 | 0.0513 | 0.0221 | 0.0863 | 0.0444 | 0.0794 | 0.0441 | 0.1054 | 0.0644 | 0.6480 | 0.8197 | 0.0042 | 0.0152 | 0.0094 | 0.0095 | 0.0147 | 0.0171 | 0.0546 | 0.0778 | 0.1322 | 0.1670 | 0.1689 | 0.2068 | 0.1186 | 0.1214 | 0.1448 | 0.1613 | 0.3526 | 0.2239 | 0.0023 | 0.0047 | 0.0088 | 0.0379 | 0.0852 | 0.1435 | 0.1144 | 0.1394 | 0.4638 | 58 | 87 | 118 | 150 | 188 | 231 | 284 | 357 | 481 | 0.0022 | 55.46 | 6.797 | 0.2505 | 97022.8 | 58800000 | 49300000000 | 53100000000000 | 0.5450 | 0.1246 | 0.0221 | 0.0008 | 0.1131 | 0.0059 | 0.2262 | 0.0326 | 0.2048 | 0.0940 | 0.1725 | 0.1716 | 0.1357 | 0.2107 | 0.0707 | 0.1674 | 0.0368 | 0.1532 | 0.0181 | 0.1637 | 0.0007 | 0.0000 | 0.0018 | 0.0009 | 0.0057 | 0.0020 | 0.0218 | 0.0142 | 0.0807 | 0.0614 | 0.1388 | 0.1041 | 0.1118 | 0.0876 | 0.1447 | 0.1228 | 0.4940 | 0.6070 | 0.0011 | 0.0025 | 0.0057 | 0.0074 | 0.0171 | 0.0319 | 0.0566 | 0.0662 | 0.1265 | 0.1363 | 0.1686 | 0.1878 | 0.1367 | 0.1099 | 0.1363 | 0.1403 | 0.3513 | 0.3178 | 0.0015 | 0.0023 | 0.0079 | 0.0347 | 0.1096 | 0.1629 | 0.1175 | 0.1597 | 0.4040 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 293 | 128 | | 4381 | 3891 | 142.2 | 45.53 | 116.54 | 68.03 | 93 | 105 | 115 | 124 | 134 | 144 | 156 | 174 | 206 | 0.1773 | 690 | 1.154 | 92.96 | 30.48 | 1 | 0.0539 | 236 | 0.0014 | 45.81 | 6.878 | 0.1869 | 22305.5 | 3870000 | 744000000 | 158000000000 | 0.4152 | 0.2335 | 0.0000 | 0.0000 | 0.0045 | 0.0003 | 0.0186 | 0.0022 | 0.0626 | 0.0091 | 0.1392 | 0.0365 | 0.1946 | 0.0890 | 0.1642 | 0.0862 | 0.1655 | 0.1307 | 0.2508 | 0.6460 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0038 | 0.0010 | 0.0190 | 0.0034 | 0.0514 | 0.0191 | 0.0936 | 0.0528 | 0.0787 | 0.0396 | 0.1148 | 0.0671 | 0.6372 | 0.8169 | 0.0021 | 0.0099 | 0.0063 | 0.0079 | 0.0264 | 0.0258 | 0.0738 | 0.0813 | 0.1276 | 0.1488 | 0.1762 | 0.1925 | 0.1171 | 0.1310 | 0.1403 | 0.1587 | 0.3302 | 0.2440 | 0.0016 | 0.0054 | 0.0136 | 0.0490 | 0.1017 | 0.1447 | 0.1181 | 0.1371 | 0.4287 | 38 | 55 | 71 | 88 | 106 | 126 | 145 | 172 | 209 | 0.0023 | 29.24 | 6.422 | 0.2512 | 18208.7 | 3510000 | 804000000 | 216000000000 | 0.4985 | 0.1471 | 0.0212 | 0.0005 | 0.0945 | 0.0070 | 0.1741 | 0.0289 | 0.1656 | 0.0690 | 0.1975 | 0.1573 | 0.1592 | 0.1669 | 0.0902 | 0.1493 | 0.0637 | 0.1728 | 0.0340 | 0.2483 | 0.0018 | 0.0000 | 0.0041 | 0.0011 | 0.0091 | 0.0040 | 0.0279 | 0.0190 | 0.0741 | 0.0623 | 0.1189 | 0.0845 | 0.1006 | 0.0758 | 0.1161 | 0.1217 | 0.5473 | 0.6316 | 0.0048 | 0.0023 | 0.0088 | 0.0137 | 0.0201 | 0.0286 | 0.0530 | 0.0766 | 0.1349 | 0.1646 | 0.1743 | 0.1737 | 0.1245 | 0.1234 | 0.1414 | 0.1349 | 0.3382 | 0.2823 | 0.0006 | 0.0069 | 0.0103 | 0.0322 | 0.0925 | 0.1516 | 0.1040 | 0.1338 | 0.4681 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 203 | 497 | | 8616 | 14575 | 174.6 | 44.13 | 171.91 | 149.45 | 122 | 138 | 150 | 161 | 171 | 181 | 192 | 207 | 232 | 0.0673 | 981 | 1.044 | 125.32 | 34.48 | 1 | 0.0331 | 285 | 0.0012 | 38.52 | 7.056 | 0.1977 | 32427.2 | 6400000 | 1340000000 | 300000000000 | 0.4569 | 0.1989 | 0.0000 | 0.0000 | 0.0017 | 0.0001 | 0.0078 | 0.0003 | 0.0287 | 0.0031 | 0.0888 | 0.0227 | 0.1586 | 0.0483 | 0.1617 | 0.0556 | 0.1808 | 0.0817 | 0.3720 | 0.7881 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0011 | 0.0383 | 0.0140 | 0.0683 | 0.0253 | 0.0693 | 0.0240 | 0.0973 | 0.0396 | 0.7154 | 0.8960 | 0.0043 | 0.0068 | 0.0129 | 0.0307 | 0.0302 | 0.0341 | 0.0851 | 0.1022 | 0.1424 | 0.1959 | 0.1763 | 0.1959 | 0.1128 | 0.1141 | 0.1375 | 0.1210 | 0.2984 | 0.1993 | 0.0015 | 0.0050 | 0.0118 | 0.0350 | 0.0866 | 0.1316 | 0.1178 | 0.1480 | 0.4626 | 22 | 43 | 68 | 99 | 135 | 170 | 218 | 279 | 376 | 0.0026 | 76.94 | 7.156 | 0.2520 | 51884.8 | 21400000 | 11000000000 | 6610000000000 | 0.4445 | 0.1894 | 0.0210 | 0.0006 | 0.0998 | 0.0058 | 0.1884 | 0.0378 | 0.1768 | 0.0812 | 0.1748 | 0.1518 | 0.1509 | 0.1963 | 0.0944 | 0.1541 | 0.0536 | 0.1491 | 0.0404 | 0.2232 | 0.0008 | 0.0002 | 0.0013 | 0.0005 | 0.0043 | 0.0019 | 0.0145 | 0.0096 | 0.0545 | 0.0413 | 0.1088 | 0.0813 | 0.0850 | 0.0660 | 0.1138 | 0.0944 | 0.6169 | 0.7048 | 0.0008 | 0.0011 | 0.0042 | 0.0066 | 0.0085 | 0.0130 | 0.0307 | 0.0414 | 0.0827 | 0.0900 | 0.1433 | 0.1572 | 0.1056 | 0.1118 | 0.1272 | 0.1359 | 0.4970 | 0.4431 | 0.0005 | 0.0029 | 0.0095 | 0.0225 | 0.0731 | 0.1165 | 0.1001 | 0.1229 | 0.5519 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1207 | 372 | | 6747 | 8059 | 84.9 | 22.08 | 226.14 | 174.03 | 59 | 67 | 72 | 77 | 82 | 87 | 94 | 102 | 115 | 0.0973 | 784 | 0.311 | 92.65 | 22.47 | 1 | 0.0539 | 364 | 0.0045 | 9.29 | 5.773 | 0.3415 | 7693.6 | 743325 | 76400000 | 8330000000 | 0.4601 | 0.1955 | 0.0008 | 0.0000 | 0.0035 | 0.0002 | 0.0171 | 0.0032 | 0.0403 | 0.0059 | 0.0875 | 0.0285 | 0.1381 | 0.0496 | 0.1482 | 0.0593 | 0.1825 | 0.0963 | 0.3819 | 0.7571 | 0.0002 | 0.0000 | 0.0006 | 0.0002 | 0.0047 | 0.0008 | 0.0110 | 0.0014 | 0.0359 | 0.0141 | 0.0685 | 0.0318 | 0.0726 | 0.0278 | 0.1047 | 0.0507 | 0.7019 | 0.8732 | 0.0043 | 0.0187 | 0.0100 | 0.0280 | 0.0278 | 0.0392 | 0.0563 | 0.1157 | 0.1069 | 0.1530 | 0.1732 | 0.1549 | 0.1354 | 0.1194 | 0.1468 | 0.1269 | 0.3393 | 0.2444 | 0.0013 | 0.0070 | 0.0152 | 0.0394 | 0.0795 | 0.1166 | 0.0994 | 0.1259 | 0.5157 | 30 | 54 | 86 | 130 | 191 | 253 | 322 | 398 | 487 | 0.0018 | 56.22 | 7.234 | 0.2526 | 81419.7 | 35200000 | 16800000000 | 8580000000000 | 0.4421 | 0.1940 | 0.0106 | 0.0013 | 0.0478 | 0.0071 | 0.1354 | 0.0260 | 0.1726 | 0.0586 | 0.2159 | 0.1525 | 0.1850 | 0.2115 | 0.1062 | 0.1406 | 0.0770 | 0.1560 | 0.0496 | 0.2464 | 0.0002 | 0.0000 | 0.0002 | 0.0011 | 0.0022 | 0.0025 | 0.0077 | 0.0053 | 0.0453 | 0.0374 | 0.0716 | 0.0706 | 0.0573 | 0.0443 | 0.0759 | 0.0693 | 0.7395 | 0.7695 | 0.0000 | 0.0000 | 0.0023 | 0.0032 | 0.0043 | 0.0056 | 0.0149 | 0.0269 | 0.0503 | 0.0622 | 0.0897 | 0.1060 | 0.0659 | 0.0779 | 0.1007 | 0.1212 | 0.6719 | 0.5969 | 0.0003 | 0.0017 | 0.0031 | 0.0136 | 0.0454 | 0.0838 | 0.0532 | 0.0830 | 0.7160 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 218 | 312 | | 2655 | 8245 | 132.8 | 44.21 | 178.73 | 118.36 | 91 | 99 | 108 | 117 | 125 | 134 | 142 | 155 | 176 | 0.0813 | 670 | 0.683 | 79.32 | 27.66 | 1 | 0.0968 | 257 | 0.0031 | 18.62 | 6.095 | 0.3246 | 19582.2 | 3340000 | 689000000 | 173000000000 | 0.4385 | 0.1979 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0062 | 0.0004 | 0.0256 | 0.0020 | 0.0622 | 0.0283 | 0.1119 | 0.0557 | 0.1140 | 0.0414 | 0.1298 | 0.0602 | 0.5497 | 0.8120 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0037 | 0.0004 | 0.0115 | 0.0015 | 0.0314 | 0.0216 | 0.0492 | 0.0352 | 0.0413 | 0.0250 | 0.0581 | 0.0367 | 0.8043 | 0.8796 | 0.0043 | 0.0000 | 0.0065 | 0.0100 | 0.0151 | 0.0100 | 0.0454 | 0.0350 | 0.1080 | 0.1100 | 0.1058 | 0.1600 | 0.0778 | 0.0750 | 0.1231 | 0.1350 | 0.5140 | 0.4650 | 0.0027 | 0.0018 | 0.0100 | 0.0255 | 0.0656 | 0.0974 | 0.0792 | 0.1193 | 0.5984 | 59 | 76 | 93 | 115 | 144 | 182 | 225 | 275 | 351 | 0.0020 | 52.90 | 6.928 | 0.2551 | 45949.6 | 15000000 | 5740000000 | 2430000000000 | 0.5074 | 0.1593 | 0.0155 | 0.0010 | 0.0882 | 0.0092 | 0.2007 | 0.0209 | 0.1771 | 0.0654 | 0.1630 | 0.1485 | 0.1441 | 0.1660 | 0.0774 | 0.1622 | 0.0566 | 0.1523 | 0.0774 | 0.2745 | 0.0005 | 0.0002 | 0.0027 | 0.0019 | 0.0060 | 0.0044 | 0.0169 | 0.0095 | 0.0638 | 0.0525 | 0.1051 | 0.0712 | 0.0744 | 0.0711 | 0.1097 | 0.0969 | 0.6210 | 0.6922 | 0.0011 | 0.0039 | 0.0068 | 0.0123 | 0.0139 | 0.0178 | 0.0444 | 0.0468 | 0.0889 | 0.0868 | 0.1213 | 0.1391 | 0.0998 | 0.1297 | 0.1348 | 0.1440 | 0.4889 | 0.4196 | 0.0009 | 0.0036 | 0.0083 | 0.0238 | 0.0753 | 0.1202 | 0.0940 | 0.1196 | 0.5542 | ||
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 77 | 299 | | 362 | 804 | 84.7 | 13.26 | 9.06 | 3.12 | 65 | 72 | 78 | 84 | 87 | 90 | 93 | 96 | 100 | 0.2786 | 224 | 0.728 | 31.40 | 8.49 | 1 | 0.2459 | 89 | 0.0508 | 1.25 | 3.272 | 0.6191 | 7352.5 | 651714 | 58800000 | 5400000000 | 0.3674 | 0.2592 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0351 | 0.0028 | 0.0596 | 0.0442 | 0.1053 | 0.0912 | 0.1368 | 0.0276 | 0.1825 | 0.0608 | 0.4737 | 0.7735 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0000 | 0.0256 | 0.0028 | 0.0415 | 0.0442 | 0.0607 | 0.0912 | 0.0607 | 0.0276 | 0.0799 | 0.0608 | 0.7252 | 0.7735 | 0.0714 | 0.0000 | 0.1429 | 0.0000 | 0.1071 | 0.0000 | 0.1429 | 0.0000 | 0.2143 | 0.0000 | 0.1786 | 0.0000 | 0.0357 | 0.0000 | 0.1071 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0048 | 0.0242 | 0.0338 | 0.0725 | 0.0725 | 0.0966 | 0.1401 | 0.5556 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 0.0140 | 20.20 | 4.617 | 0.2555 | 91.8 | 1010.84 | 11937.1 | 150060 | 0.5369 | 0.1144 | 0.0442 | 0.0017 | 0.1633 | 0.0034 | 0.2449 | 0.0458 | 0.2415 | 0.1171 | 0.1565 | 0.1460 | 0.0884 | 0.2530 | 0.0476 | 0.2054 | 0.0102 | 0.1562 | 0.0034 | 0.0713 | 0.0018 | 0.0000 | 0.0235 | 0.0000 | 0.0470 | 0.0056 | 0.1302 | 0.0405 | 0.2061 | 0.1103 | 0.2188 | 0.1494 | 0.2116 | 0.1955 | 0.1157 | 0.2598 | 0.0452 | 0.2388 | 0.1042 | 0.3150 | 0.2008 | 0.3858 | 0.2124 | 0.2283 | 0.2432 | 0.0394 | 0.1236 | 0.0315 | 0.0811 | 0.0000 | 0.0270 | 0.0000 | 0.0077 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0424 | 0.1038 | 0.2076 | 0.2182 | 0.1801 | 0.1547 | 0.0657 | 0.0233 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 819 | 741 | | 5979 | 6896 | 220.8 | 55.20 | 179.58 | 138.54 | 160 | 176 | 189 | 201 | 212 | 224 | 239 | 259 | 290 | 0.1115 | 769 | 1.055 | 105.12 | 32.02 | 1 | 0.0418 | 250 | 0.0010 | 54.65 | 7.224 | 0.1685 | 51796.9 | 13000000 | 3490000000 | 1010000000000 | 0.4435 | 0.2077 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0040 | 0.0000 | 0.0187 | 0.0015 | 0.0749 | 0.0195 | 0.1570 | 0.0462 | 0.1484 | 0.0436 | 0.1840 | 0.0676 | 0.4128 | 0.8214 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0000 | 0.0059 | 0.0002 | 0.0381 | 0.0134 | 0.0733 | 0.0232 | 0.0677 | 0.0209 | 0.1008 | 0.0375 | 0.7133 | 0.9047 | 0.0048 | 0.0024 | 0.0107 | 0.0000 | 0.0213 | 0.0095 | 0.0804 | 0.0735 | 0.1231 | 0.1659 | 0.1841 | 0.2109 | 0.0940 | 0.0948 | 0.1260 | 0.1469 | 0.3556 | 0.2962 | 0.0016 | 0.0020 | 0.0102 | 0.0317 | 0.0939 | 0.1412 | 0.1146 | 0.1451 | 0.4597 | 35 | 59 | 83 | 111 | 142 | 182 | 230 | 292 | 373 | 0.0020 | 58.17 | 6.937 | 0.2558 | 51437.9 | 19300000 | 8700000000 | 4480000000000 | 0.5354 | 0.1275 | 0.0234 | 0.0012 | 0.1292 | 0.0079 | 0.2559 | 0.0540 | 0.1882 | 0.1092 | 0.1683 | 0.1926 | 0.1110 | 0.1934 | 0.0642 | 0.1357 | 0.0399 | 0.1274 | 0.0199 | 0.1785 | 0.0000 | 0.0000 | 0.0012 | 0.0007 | 0.0041 | 0.0040 | 0.0199 | 0.0119 | 0.0809 | 0.0632 | 0.1232 | 0.1038 | 0.0870 | 0.0722 | 0.1300 | 0.1109 | 0.5537 | 0.6333 | 0.0022 | 0.0006 | 0.0018 | 0.0033 | 0.0106 | 0.0155 | 0.0343 | 0.0472 | 0.1004 | 0.1210 | 0.1612 | 0.1805 | 0.1233 | 0.1260 | 0.1440 | 0.1460 | 0.4223 | 0.3598 | 0.0018 | 0.0029 | 0.0068 | 0.0310 | 0.0863 | 0.1320 | 0.1059 | 0.1469 | 0.4864 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 942 | 402 | | 3688 | 2332 | 151.8 | 43.28 | 180.50 | 133.21 | 108 | 117 | 125 | 132 | 140 | 151 | 164 | 182 | 212 | 0.2213 | 516 | 0.931 | 141.17 | 32.02 | 1 | 0.0876 | 323 | 0.0019 | 31.70 | 6.606 | 0.2258 | 24909.7 | 4450000 | 865000000 | 182000000000 | 0.4279 | 0.2128 | 0.0005 | 0.0000 | 0.0025 | 0.0003 | 0.0128 | 0.0000 | 0.0325 | 0.0040 | 0.1019 | 0.0306 | 0.1791 | 0.0553 | 0.1713 | 0.0550 | 0.1688 | 0.0767 | 0.3307 | 0.7782 | 0.0004 | 0.0000 | 0.0015 | 0.0003 | 0.0062 | 0.0000 | 0.0124 | 0.0017 | 0.0433 | 0.0179 | 0.0822 | 0.0261 | 0.0803 | 0.0228 | 0.1047 | 0.0391 | 0.6692 | 0.8922 | 0.0014 | 0.0000 | 0.0083 | 0.0028 | 0.0139 | 0.0165 | 0.0584 | 0.0771 | 0.1210 | 0.1460 | 0.1919 | 0.1983 | 0.1099 | 0.1102 | 0.1140 | 0.1295 | 0.3811 | 0.3196 | 0.0000 | 0.0041 | 0.0129 | 0.0272 | 0.0918 | 0.1162 | 0.0959 | 0.1312 | 0.5207 | 34 | 55 | 81 | 119 | 156 | 194 | 239 | 293 | 359 | 0.0027 | 61.54 | 6.549 | 0.2559 | 50319.2 | 17900000 | 7550000000 | 3670000000000 | 0.4809 | 0.1585 | 0.0235 | 0.0000 | 0.1362 | 0.0214 | 0.1643 | 0.0571 | 0.2136 | 0.1060 | 0.1573 | 0.1655 | 0.1221 | 0.2143 | 0.0798 | 0.1429 | 0.0540 | 0.1179 | 0.0493 | 0.1750 | 0.0000 | 0.0000 | 0.0048 | 0.0027 | 0.0137 | 0.0096 | 0.0299 | 0.0212 | 0.0792 | 0.0745 | 0.1317 | 0.1217 | 0.0800 | 0.0820 | 0.1309 | 0.1046 | 0.5299 | 0.5837 | 0.0037 | 0.0032 | 0.0111 | 0.0064 | 0.0172 | 0.0305 | 0.0382 | 0.0546 | 0.1207 | 0.1396 | 0.1736 | 0.1862 | 0.1219 | 0.1348 | 0.1515 | 0.1605 | 0.3621 | 0.2841 | 0.0020 | 0.0079 | 0.0188 | 0.0327 | 0.0962 | 0.1409 | 0.1111 | 0.1518 | 0.4385 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 232 | 638 | | 6254 | 5949 | 114.7 | 25.41 | 187.62 | 143.24 | 87 | 94 | 100 | 105 | 110 | 116 | 123 | 132 | 150 | 0.1308 | 778 | 0.961 | 106.23 | 31.32 | 1 | 0.0421 | 263 | 0.0034 | 14.14 | 6.046 | 0.2876 | 13792.0 | 1750000 | 233000000 | 32800000000 | 0.4648 | 0.1869 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0092 | 0.0003 | 0.0230 | 0.0024 | 0.0653 | 0.0177 | 0.1219 | 0.0491 | 0.1387 | 0.0346 | 0.1702 | 0.0694 | 0.4696 | 0.8265 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0003 | 0.0324 | 0.0105 | 0.0605 | 0.0277 | 0.0714 | 0.0137 | 0.0961 | 0.0290 | 0.7274 | 0.9189 | 0.0097 | 0.0198 | 0.0117 | 0.0074 | 0.0272 | 0.0272 | 0.0690 | 0.0743 | 0.1370 | 0.2030 | 0.1594 | 0.1807 | 0.1108 | 0.1436 | 0.1429 | 0.1337 | 0.3324 | 0.2104 | 0.0023 | 0.0109 | 0.0214 | 0.0436 | 0.1019 | 0.1320 | 0.1169 | 0.1421 | 0.4289 | 42 | 65 | 88 | 115 | 148 | 183 | 233 | 303 | 394 | 0.0021 | 69.90 | 6.913 | 0.2582 | 55713.5 | 21700000 | 10100000000 | 5300000000000 | 0.5779 | 0.0961 | 0.0346 | 0.0023 | 0.1508 | 0.0121 | 0.2315 | 0.0680 | 0.1585 | 0.1253 | 0.1537 | 0.1524 | 0.1162 | 0.1729 | 0.0836 | 0.1356 | 0.0500 | 0.1212 | 0.0211 | 0.2102 | 0.0017 | 0.0003 | 0.0017 | 0.0017 | 0.0069 | 0.0050 | 0.0247 | 0.0182 | 0.0897 | 0.0636 | 0.1357 | 0.1151 | 0.1103 | 0.0851 | 0.1454 | 0.1258 | 0.4838 | 0.5854 | 0.0016 | 0.0047 | 0.0064 | 0.0034 | 0.0112 | 0.0229 | 0.0508 | 0.0518 | 0.1086 | 0.1312 | 0.1825 | 0.1783 | 0.1215 | 0.1285 | 0.1429 | 0.1406 | 0.3745 | 0.3385 | 0.0004 | 0.0017 | 0.0120 | 0.0322 | 0.1043 | 0.1550 | 0.1245 | 0.1426 | 0.4272 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 916 | 643 | | 6177 | 7967 | 199.4 | 44.34 | 175.07 | 133.71 | 150 | 163 | 173 | 182 | 192 | 203 | 216 | 234 | 259 | 0.0964 | 768 | 0.994 | 106.57 | 33.42 | 1 | 0.0440 | 272 | 0.0013 | 36.60 | 6.944 | 0.1957 | 41711.5 | 9180000 | 2130000000 | 520000000000 | 0.4243 | 0.2275 | 0.0010 | 0.0000 | 0.0007 | 0.0000 | 0.0032 | 0.0000 | 0.0168 | 0.0009 | 0.0753 | 0.0176 | 0.1308 | 0.0425 | 0.1402 | 0.0375 | 0.1836 | 0.0678 | 0.4482 | 0.8336 | 0.0006 | 0.0000 | 0.0004 | 0.0000 | 0.0016 | 0.0000 | 0.0076 | 0.0005 | 0.0326 | 0.0112 | 0.0591 | 0.0230 | 0.0595 | 0.0150 | 0.0870 | 0.0231 | 0.7518 | 0.9272 | 0.0009 | 0.0179 | 0.0091 | 0.0358 | 0.0174 | 0.0657 | 0.0659 | 0.1343 | 0.1473 | 0.1433 | 0.1738 | 0.1791 | 0.1363 | 0.0955 | 0.1537 | 0.1164 | 0.2955 | 0.2119 | 0.0011 | 0.0033 | 0.0110 | 0.0375 | 0.0824 | 0.1191 | 0.1085 | 0.1393 | 0.4978 | 30 | 56 | 84 | 112 | 145 | 182 | 223 | 277 | 360 | 0.0025 | 69.87 | 6.927 | 0.2586 | 48522.6 | 17600000 | 7750000000 | 3970000000000 | 0.4873 | 0.1778 | 0.0220 | 0.0017 | 0.1111 | 0.0031 | 0.1870 | 0.0584 | 0.1544 | 0.1117 | 0.1816 | 0.1633 | 0.1457 | 0.1879 | 0.0951 | 0.1507 | 0.0552 | 0.1240 | 0.0479 | 0.1992 | 0.0002 | 0.0004 | 0.0014 | 0.0006 | 0.0029 | 0.0018 | 0.0145 | 0.0127 | 0.0737 | 0.0543 | 0.1090 | 0.0980 | 0.0872 | 0.0692 | 0.1206 | 0.1000 | 0.5904 | 0.6629 | 0.0015 | 0.0034 | 0.0019 | 0.0029 | 0.0087 | 0.0147 | 0.0417 | 0.0563 | 0.1059 | 0.1337 | 0.1647 | 0.1768 | 0.1097 | 0.1254 | 0.1514 | 0.1528 | 0.4144 | 0.3340 | 0.0006 | 0.0033 | 0.0072 | 0.0275 | 0.0899 | 0.1341 | 0.1039 | 0.1338 | 0.4997 |