High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1052 | 237 | | 1244 | 2214 | 114.3 | 23.44 | 7.50 | 2.80 | 84 | 94 | 100 | 107 | 113 | 120 | 127 | 134 | 145 | 0.1920 | 425 | 1.281 | 34.41 | 15.23 | 1 | 0.0748 | 93 | 0.0239 | 1.48 | 4.012 | 0.6161 | 13623.0 | 1690000 | 216000000 | 28600000000 | 0.3972 | 0.2379 | 0.0012 | 0.0000 | 0.0000 | 0.0008 | 0.0075 | 0.0034 | 0.0187 | 0.0034 | 0.0748 | 0.0322 | 0.1097 | 0.0593 | 0.1222 | 0.0364 | 0.1534 | 0.0653 | 0.5125 | 0.7992 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0008 | 0.0088 | 0.0024 | 0.0362 | 0.0276 | 0.0480 | 0.0487 | 0.0490 | 0.0244 | 0.0803 | 0.0414 | 0.7747 | 0.8547 | 0.0000 | 0.0192 | 0.0183 | 0.0000 | 0.0137 | 0.0577 | 0.0822 | 0.0769 | 0.1187 | 0.1538 | 0.1187 | 0.1538 | 0.1187 | 0.1154 | 0.1461 | 0.2692 | 0.3836 | 0.1538 | 0.0016 | 0.0049 | 0.0098 | 0.0276 | 0.0683 | 0.0862 | 0.0992 | 0.1382 | 0.5642 | 4 | 5 | 6 | 6 | 8 | 8 | 9 | 10 | 11 | 0.0155 | 11.39 | 4.516 | 0.3088 | 64.1 | 606.433 | 6239.84 | 68969.9 | 0.5222 | 0.1520 | 0.0555 | 0.0000 | 0.1778 | 0.0044 | 0.2383 | 0.0172 | 0.2497 | 0.0498 | 0.1728 | 0.1007 | 0.0757 | 0.1638 | 0.0240 | 0.1970 | 0.0063 | 0.2601 | 0.0000 | 0.2070 | 0.0182 | 0.0000 | 0.0507 | 0.0020 | 0.0954 | 0.0096 | 0.1105 | 0.0359 | 0.1294 | 0.0759 | 0.1658 | 0.1128 | 0.1400 | 0.1224 | 0.1726 | 0.2124 | 0.1173 | 0.4289 | 0.1080 | 0.3059 | 0.1667 | 0.1588 | 0.1212 | 0.2059 | 0.1477 | 0.1294 | 0.1496 | 0.1412 | 0.1591 | 0.0353 | 0.1080 | 0.0176 | 0.0265 | 0.0059 | 0.0133 | 0.0000 | 0.0367 | 0.0752 | 0.1235 | 0.1074 | 0.1406 | 0.1352 | 0.1227 | 0.1513 | 0.1074 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1142 | 279 | | 6081 | 12680 | 333.3 | 75.05 | 132.72 | 150.99 | 244 | 268 | 287 | 305 | 325 | 343 | 366 | 393 | 433 | 0.0758 | 961 | 1.101 | 113.36 | 37.12 | 1 | 0.0462 | 281 | 0.0013 | 26.51 | 6.910 | 0.2088 | 116744.0 | 43000000 | 16600000000 | 6710000000000 | 0.3801 | 0.2654 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0042 | 0.0000 | 0.0168 | 0.0011 | 0.0633 | 0.0200 | 0.1116 | 0.0341 | 0.1355 | 0.0320 | 0.1721 | 0.0541 | 0.4938 | 0.8587 | 0.0004 | 0.0000 | 0.0010 | 0.0000 | 0.0020 | 0.0000 | 0.0071 | 0.0005 | 0.0310 | 0.0141 | 0.0482 | 0.0230 | 0.0586 | 0.0181 | 0.0796 | 0.0318 | 0.7721 | 0.9125 | 0.0037 | 0.0088 | 0.0119 | 0.0117 | 0.0165 | 0.0263 | 0.0567 | 0.0380 | 0.1033 | 0.1082 | 0.1435 | 0.1345 | 0.1060 | 0.0936 | 0.1389 | 0.1082 | 0.4196 | 0.4708 | 0.0018 | 0.0043 | 0.0093 | 0.0205 | 0.0751 | 0.1053 | 0.0830 | 0.1165 | 0.5841 | 10 | 15 | 26 | 48 | 77 | 111 | 158 | 228 | 346 | 0.0156 | 26.28 | 5.931 | 0.4048 | 40411.4 | 17400000 | 9060000000 | 5290000000000 | 0.5025 | 0.1413 | 0.0228 | 0.0017 | 0.0773 | 0.0063 | 0.1471 | 0.0370 | 0.1547 | 0.0783 | 0.1747 | 0.1540 | 0.1485 | 0.1778 | 0.1105 | 0.1249 | 0.0905 | 0.1378 | 0.0739 | 0.2822 | 0.0000 | 0.0006 | 0.0013 | 0.0013 | 0.0013 | 0.0021 | 0.0136 | 0.0091 | 0.0417 | 0.0414 | 0.0724 | 0.0662 | 0.0582 | 0.0462 | 0.0751 | 0.0721 | 0.7364 | 0.7610 | 0.0003 | 0.0006 | 0.0021 | 0.0031 | 0.0040 | 0.0037 | 0.0143 | 0.0131 | 0.0562 | 0.0601 | 0.0816 | 0.1055 | 0.0776 | 0.0812 | 0.1052 | 0.1173 | 0.6588 | 0.6153 | 0.0014 | 0.0020 | 0.0034 | 0.0108 | 0.0473 | 0.0756 | 0.0567 | 0.0882 | 0.7146 | ||
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 504 | 454 | | 4632 | 9949 | 526.7 | 103.94 | 144.23 | 161.03 | 403 | 434 | 461 | 488 | 517 | 541 | 573 | 613 | 674 | 0.0767 | 763 | 1.167 | 101.13 | 34.54 | 1 | 0.0531 | 246 | 0.0009 | 55.30 | 7.231 | 0.1624 | 288245.0 | 164000000 | 96700000000 | 59100000000000 | 0.4365 | 0.2052 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0095 | 0.0004 | 0.0653 | 0.0181 | 0.1242 | 0.0349 | 0.1378 | 0.0329 | 0.1714 | 0.0511 | 0.4897 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0044 | 0.0002 | 0.0279 | 0.0136 | 0.0541 | 0.0242 | 0.0597 | 0.0141 | 0.0859 | 0.0249 | 0.7668 | 0.9230 | 0.0054 | 0.0188 | 0.0054 | 0.0125 | 0.0201 | 0.0313 | 0.0698 | 0.1438 | 0.1557 | 0.2438 | 0.1906 | 0.1750 | 0.1302 | 0.1188 | 0.1664 | 0.1563 | 0.2564 | 0.1000 | 0.0009 | 0.0038 | 0.0033 | 0.0302 | 0.0797 | 0.1282 | 0.1249 | 0.1556 | 0.4734 | 18 | 28 | 46 | 67 | 93 | 124 | 163 | 220 | 330 | 0.0156 | 19.65 | 5.459 | 0.4608 | 46729.0 | 24700000 | 17300000000 | 14400000000000 | 0.5530 | 0.1302 | 0.0176 | 0.0010 | 0.1067 | 0.0100 | 0.2360 | 0.0424 | 0.1854 | 0.0883 | 0.1601 | 0.1621 | 0.1292 | 0.2014 | 0.0730 | 0.1717 | 0.0597 | 0.1438 | 0.0323 | 0.1793 | 0.0002 | 0.0000 | 0.0009 | 0.0012 | 0.0024 | 0.0019 | 0.0176 | 0.0129 | 0.0691 | 0.0574 | 0.1203 | 0.0945 | 0.0888 | 0.0781 | 0.1108 | 0.1107 | 0.5899 | 0.6432 | 0.0004 | 0.0009 | 0.0011 | 0.0022 | 0.0061 | 0.0106 | 0.0301 | 0.0396 | 0.1050 | 0.1091 | 0.1384 | 0.1552 | 0.0986 | 0.0994 | 0.1376 | 0.1271 | 0.4828 | 0.4560 | 0.0017 | 0.0012 | 0.0043 | 0.0240 | 0.0822 | 0.1343 | 0.0909 | 0.1308 | 0.5305 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1090 | 760 | | 3567 | 11438 | 100.2 | 24.43 | 44.83 | 30.71 | 75 | 81 | 85 | 89 | 93 | 99 | 107 | 120 | 138 | 0.1156 | 1322 | 1.193 | 93.86 | 31.91 | 1 | 0.0648 | 231 | 0.0052 | 8.86 | 5.685 | 0.3588 | 10638.8 | 1200000 | 144000000 | 18300000000 | 0.5064 | 0.1576 | 0.0023 | 0.0003 | 0.0099 | 0.0003 | 0.0208 | 0.0025 | 0.0406 | 0.0084 | 0.0848 | 0.0491 | 0.1196 | 0.0870 | 0.1255 | 0.0600 | 0.1512 | 0.0901 | 0.4454 | 0.7022 | 0.0017 | 0.0000 | 0.0065 | 0.0000 | 0.0075 | 0.0014 | 0.0222 | 0.0056 | 0.0491 | 0.0352 | 0.0713 | 0.0681 | 0.0699 | 0.0405 | 0.0883 | 0.0602 | 0.6835 | 0.7889 | 0.0070 | 0.0179 | 0.0098 | 0.0208 | 0.0223 | 0.0119 | 0.0377 | 0.0327 | 0.0628 | 0.0744 | 0.0964 | 0.1220 | 0.0712 | 0.0804 | 0.0936 | 0.1042 | 0.5992 | 0.5357 | 0.0042 | 0.0063 | 0.0134 | 0.0324 | 0.0746 | 0.0824 | 0.0866 | 0.1056 | 0.5944 | 11 | 17 | 23 | 31 | 40 | 49 | 58 | 68 | 84 | 0.0159 | 3.14 | 4.641 | 0.5376 | 2952.1 | 252025 | 26700000 | 3450000000 | 0.5531 | 0.1427 | 0.0123 | 0.0087 | 0.0497 | 0.0166 | 0.1286 | 0.0231 | 0.1677 | 0.0522 | 0.1986 | 0.1185 | 0.1774 | 0.1539 | 0.1341 | 0.1548 | 0.0925 | 0.1952 | 0.0390 | 0.2770 | 0.0024 | 0.0039 | 0.0044 | 0.0055 | 0.0071 | 0.0049 | 0.0198 | 0.0124 | 0.0492 | 0.0397 | 0.0746 | 0.0608 | 0.0741 | 0.0533 | 0.1097 | 0.0866 | 0.6586 | 0.7329 | 0.0035 | 0.0089 | 0.0079 | 0.0171 | 0.0208 | 0.0250 | 0.0406 | 0.0545 | 0.0844 | 0.1094 | 0.1267 | 0.1306 | 0.1138 | 0.1248 | 0.1473 | 0.1608 | 0.4550 | 0.3689 | 0.0023 | 0.0047 | 0.0093 | 0.0271 | 0.0662 | 0.0972 | 0.1038 | 0.1410 | 0.5484 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1021 | 289 | | 15480 | 20962 | 107.9 | 32.54 | 126.87 | 115.24 | 70 | 80 | 88 | 96 | 104 | 112 | 122 | 133 | 151 | 0.0665 | 1394 | 1.246 | 41.87 | 18.36 | 4 | 0.0075 | 116 | 0.0011 | 32.98 | 7.115 | 0.2122 | 12708.7 | 1630000 | 225000000 | 33600000000 | 0.4430 | 0.2071 | 0.0021 | 0.0002 | 0.0042 | 0.0005 | 0.0146 | 0.0012 | 0.0424 | 0.0071 | 0.1092 | 0.0273 | 0.1709 | 0.0639 | 0.1595 | 0.0673 | 0.1788 | 0.1076 | 0.3183 | 0.7248 | 0.0014 | 0.0002 | 0.0020 | 0.0003 | 0.0039 | 0.0009 | 0.0118 | 0.0037 | 0.0393 | 0.0149 | 0.0650 | 0.0333 | 0.0601 | 0.0290 | 0.0876 | 0.0504 | 0.7289 | 0.8672 | 0.0025 | 0.0080 | 0.0037 | 0.0173 | 0.0202 | 0.0306 | 0.0567 | 0.0766 | 0.1110 | 0.1671 | 0.1514 | 0.1598 | 0.1194 | 0.1152 | 0.1455 | 0.1418 | 0.3896 | 0.2836 | 0.0011 | 0.0021 | 0.0090 | 0.0274 | 0.0627 | 0.1065 | 0.0944 | 0.1225 | 0.5742 | 16 | 27 | 45 | 67 | 94 | 124 | 161 | 212 | 289 | 0.0159 | 8.96 | 5.332 | 0.5036 | 29376.6 | 9390000 | 3750000000 | 1790000000000 | 0.4948 | 0.1572 | 0.0112 | 0.0016 | 0.0613 | 0.0068 | 0.1433 | 0.0245 | 0.1682 | 0.0618 | 0.1919 | 0.1370 | 0.1645 | 0.1771 | 0.1051 | 0.1416 | 0.0836 | 0.1568 | 0.0709 | 0.2928 | 0.0008 | 0.0004 | 0.0011 | 0.0016 | 0.0035 | 0.0026 | 0.0133 | 0.0076 | 0.0489 | 0.0371 | 0.0788 | 0.0577 | 0.0640 | 0.0520 | 0.0930 | 0.0767 | 0.6966 | 0.7643 | 0.0006 | 0.0013 | 0.0028 | 0.0020 | 0.0070 | 0.0071 | 0.0249 | 0.0329 | 0.0705 | 0.0821 | 0.1139 | 0.1305 | 0.0891 | 0.1028 | 0.1163 | 0.1349 | 0.5748 | 0.5065 | 0.0001 | 0.0018 | 0.0055 | 0.0186 | 0.0602 | 0.0898 | 0.0819 | 0.1099 | 0.6321 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 976 | 862 | | 8371 | 10040 | 119.6 | 44.92 | 155.74 | 155.70 | 66 | 82 | 94 | 104 | 115 | 126 | 139 | 155 | 180 | 0.1011 | 1015 | 0.966 | 89.94 | 27.51 | 4 | 0.0288 | 241 | 0.0007 | 62.88 | 7.556 | 0.1767 | 16326.4 | 2490000 | 417000000 | 75800000000 | 0.4543 | 0.2049 | 0.0006 | 0.0000 | 0.0058 | 0.0003 | 0.0252 | 0.0021 | 0.0659 | 0.0106 | 0.1494 | 0.0457 | 0.1923 | 0.0930 | 0.1593 | 0.0951 | 0.1636 | 0.1235 | 0.2379 | 0.6298 | 0.0002 | 0.0000 | 0.0010 | 0.0001 | 0.0033 | 0.0005 | 0.0121 | 0.0036 | 0.0500 | 0.0240 | 0.0668 | 0.0448 | 0.0596 | 0.0367 | 0.0870 | 0.0539 | 0.7200 | 0.8364 | 0.0009 | 0.0034 | 0.0035 | 0.0017 | 0.0132 | 0.0299 | 0.0475 | 0.0708 | 0.1174 | 0.1561 | 0.1500 | 0.1698 | 0.1047 | 0.0998 | 0.1341 | 0.1519 | 0.4288 | 0.3166 | 0.0011 | 0.0037 | 0.0045 | 0.0250 | 0.0677 | 0.1195 | 0.0937 | 0.1219 | 0.5629 | 15 | 25 | 47 | 74 | 107 | 150 | 200 | 260 | 359 | 0.0159 | 26.97 | 5.856 | 0.3967 | 48494.1 | 21800000 | 12600000000 | 8830000000000 | 0.5977 | 0.0835 | 0.0353 | 0.0018 | 0.1603 | 0.0185 | 0.3052 | 0.0912 | 0.1733 | 0.1119 | 0.1411 | 0.1866 | 0.1005 | 0.2165 | 0.0460 | 0.1263 | 0.0314 | 0.1278 | 0.0069 | 0.1193 | 0.0002 | 0.0006 | 0.0011 | 0.0009 | 0.0055 | 0.0039 | 0.0196 | 0.0131 | 0.0627 | 0.0586 | 0.1262 | 0.1037 | 0.0878 | 0.0736 | 0.1216 | 0.1085 | 0.5754 | 0.6371 | 0.0006 | 0.0030 | 0.0043 | 0.0059 | 0.0101 | 0.0111 | 0.0336 | 0.0392 | 0.0864 | 0.1103 | 0.1639 | 0.1799 | 0.1184 | 0.1136 | 0.1334 | 0.1358 | 0.4495 | 0.4012 | 0.0008 | 0.0015 | 0.0069 | 0.0240 | 0.0769 | 0.1428 | 0.0979 | 0.1329 | 0.5164 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 866 | 124 | | 7868 | 18298 | 509.3 | 103.27 | 71.24 | 63.85 | 380 | 418 | 450 | 475 | 502 | 530 | 561 | 596 | 645 | 0.0624 | 1141 | 1.024 | 98.60 | 36.00 | 1 | 0.0336 | 264 | 0.0007 | 43.87 | 7.460 | 0.1703 | 270039.0 | 149000000 | 85000000000 | 50300000000000 | 0.4294 | 0.2140 | 0.0004 | 0.0000 | 0.0011 | 0.0001 | 0.0029 | 0.0005 | 0.0116 | 0.0009 | 0.0506 | 0.0141 | 0.0958 | 0.0303 | 0.1076 | 0.0255 | 0.1326 | 0.0412 | 0.5975 | 0.8874 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0001 | 0.0044 | 0.0005 | 0.0218 | 0.0097 | 0.0421 | 0.0212 | 0.0456 | 0.0141 | 0.0611 | 0.0214 | 0.8231 | 0.9329 | 0.0015 | 0.0151 | 0.0115 | 0.0075 | 0.0137 | 0.0491 | 0.0634 | 0.0943 | 0.0977 | 0.1698 | 0.1504 | 0.1698 | 0.1107 | 0.1132 | 0.1427 | 0.1208 | 0.4084 | 0.2604 | 0.0005 | 0.0021 | 0.0061 | 0.0192 | 0.0541 | 0.0908 | 0.0842 | 0.1111 | 0.6320 | 12 | 20 | 32 | 44 | 56 | 67 | 82 | 103 | 155 | 0.0160 | 5.43 | 4.946 | 0.5259 | 9151.3 | 1720000 | 410000000 | 113000000000 | 0.3977 | 0.2161 | 0.0063 | 0.0014 | 0.0287 | 0.0034 | 0.0848 | 0.0127 | 0.1175 | 0.0402 | 0.1734 | 0.0962 | 0.1759 | 0.1181 | 0.1582 | 0.1348 | 0.1455 | 0.1664 | 0.1097 | 0.4269 | 0.0011 | 0.0006 | 0.0036 | 0.0013 | 0.0059 | 0.0046 | 0.0190 | 0.0127 | 0.0462 | 0.0332 | 0.0641 | 0.0471 | 0.0697 | 0.0516 | 0.0984 | 0.0760 | 0.6920 | 0.7730 | 0.0018 | 0.0028 | 0.0049 | 0.0062 | 0.0101 | 0.0130 | 0.0352 | 0.0370 | 0.0677 | 0.0795 | 0.0948 | 0.0956 | 0.0883 | 0.0857 | 0.1176 | 0.1134 | 0.5795 | 0.5667 | 0.0029 | 0.0063 | 0.0092 | 0.0245 | 0.0550 | 0.0789 | 0.0782 | 0.1114 | 0.6337 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 857 | 519 | | 7896 | 25086 | 549.1 | 111.64 | 115.29 | 108.29 | 407 | 452 | 487 | 515 | 543 | 571 | 603 | 640 | 694 | 0.0453 | 1137 | 0.998 | 121.50 | 33.97 | 1 | 0.0384 | 303 | 0.0006 | 71.62 | 7.693 | 0.1462 | 313964.0 | 187000000 | 115000000000 | 73300000000000 | 0.4442 | 0.2062 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0000 | 0.0110 | 0.0013 | 0.0526 | 0.0162 | 0.1198 | 0.0335 | 0.1264 | 0.0258 | 0.1582 | 0.0429 | 0.5295 | 0.8802 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0000 | 0.0247 | 0.0109 | 0.0576 | 0.0223 | 0.0544 | 0.0138 | 0.0738 | 0.0246 | 0.7850 | 0.9284 | 0.0055 | 0.0067 | 0.0079 | 0.0134 | 0.0259 | 0.0235 | 0.0715 | 0.0705 | 0.1155 | 0.1779 | 0.1595 | 0.2315 | 0.1147 | 0.1409 | 0.1304 | 0.1342 | 0.3692 | 0.2013 | 0.0003 | 0.0021 | 0.0045 | 0.0279 | 0.0760 | 0.1244 | 0.0942 | 0.1323 | 0.5384 | 14 | 19 | 30 | 51 | 80 | 116 | 158 | 205 | 271 | 0.0163 | 18.42 | 5.849 | 0.4162 | 25016.0 | 7180000 | 2480000000 | 993000000000 | 0.4965 | 0.1507 | 0.0497 | 0.0008 | 0.2062 | 0.0128 | 0.2854 | 0.1255 | 0.1474 | 0.1729 | 0.1169 | 0.1868 | 0.0873 | 0.1793 | 0.0490 | 0.1096 | 0.0336 | 0.0972 | 0.0245 | 0.1151 | 0.0003 | 0.0000 | 0.0008 | 0.0004 | 0.0022 | 0.0018 | 0.0130 | 0.0103 | 0.0633 | 0.0528 | 0.1135 | 0.0937 | 0.0729 | 0.0627 | 0.1138 | 0.0990 | 0.6201 | 0.6793 | 0.0006 | 0.0004 | 0.0013 | 0.0031 | 0.0045 | 0.0078 | 0.0266 | 0.0355 | 0.0880 | 0.1026 | 0.1507 | 0.1609 | 0.0929 | 0.1075 | 0.1339 | 0.1393 | 0.5016 | 0.4429 | 0.0004 | 0.0013 | 0.0028 | 0.0194 | 0.0737 | 0.1338 | 0.0833 | 0.1256 | 0.5598 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 836 | 239 | | 7959 | 17179 | 111.4 | 30.75 | 133.54 | 119.53 | 79 | 87 | 93 | 99 | 105 | 113 | 122 | 134 | 152 | 0.0646 | 1109 | 0.889 | 111.63 | 30.02 | 1 | 0.0362 | 288 | 0.0014 | 37.17 | 6.950 | 0.2080 | 13344.8 | 1730000 | 244000000 | 37300000000 | 0.4636 | 0.2058 | 0.0004 | 0.0000 | 0.0029 | 0.0004 | 0.0141 | 0.0018 | 0.0306 | 0.0034 | 0.0937 | 0.0251 | 0.1737 | 0.0627 | 0.1673 | 0.0617 | 0.1958 | 0.0914 | 0.3214 | 0.7534 | 0.0002 | 0.0000 | 0.0008 | 0.0003 | 0.0051 | 0.0005 | 0.0142 | 0.0017 | 0.0425 | 0.0148 | 0.0738 | 0.0327 | 0.0751 | 0.0242 | 0.1032 | 0.0422 | 0.6851 | 0.8836 | 0.0013 | 0.0058 | 0.0106 | 0.0101 | 0.0188 | 0.0361 | 0.0625 | 0.1111 | 0.1370 | 0.1789 | 0.1739 | 0.2136 | 0.1169 | 0.0823 | 0.1382 | 0.1270 | 0.3408 | 0.2352 | 0.0021 | 0.0050 | 0.0085 | 0.0349 | 0.0830 | 0.1306 | 0.1065 | 0.1317 | 0.4977 | 15 | 24 | 44 | 68 | 100 | 138 | 175 | 228 | 307 | 0.0163 | 13.12 | 5.549 | 0.4536 | 32119.0 | 10100000 | 3750000000 | 1560000000000 | 0.4503 | 0.2056 | 0.0225 | 0.0016 | 0.0936 | 0.0063 | 0.1855 | 0.0369 | 0.1578 | 0.0822 | 0.1606 | 0.1574 | 0.1341 | 0.1888 | 0.1020 | 0.1438 | 0.0831 | 0.1533 | 0.0606 | 0.2296 | 0.0006 | 0.0006 | 0.0006 | 0.0006 | 0.0026 | 0.0026 | 0.0117 | 0.0095 | 0.0448 | 0.0361 | 0.0845 | 0.0642 | 0.0655 | 0.0513 | 0.0979 | 0.0846 | 0.6919 | 0.7505 | 0.0012 | 0.0017 | 0.0042 | 0.0036 | 0.0080 | 0.0091 | 0.0245 | 0.0282 | 0.0726 | 0.0896 | 0.1213 | 0.1353 | 0.0980 | 0.1046 | 0.1294 | 0.1292 | 0.5407 | 0.4988 | 0.0004 | 0.0006 | 0.0042 | 0.0167 | 0.0586 | 0.0988 | 0.0853 | 0.1203 | 0.6151 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1179 | 189 | | 16382 | 26563 | 119.9 | 50.77 | 96.33 | 96.08 | 57 | 80 | 93 | 105 | 115 | 128 | 142 | 159 | 186 | 0.0652 | 1732 | 0.279 | 134.45 | 18.44 | 8 | 0.0245 | 401 | 0.0012 | 34.16 | 7.111 | 0.2279 | 16954.2 | 2720000 | 485000000 | 94900000000 | 0.4885 | 0.1704 | 0.0014 | 0.0001 | 0.0069 | 0.0005 | 0.0266 | 0.0024 | 0.0715 | 0.0104 | 0.1597 | 0.0480 | 0.2113 | 0.0993 | 0.1753 | 0.1092 | 0.1597 | 0.1428 | 0.1876 | 0.5873 | 0.0004 | 0.0001 | 0.0017 | 0.0003 | 0.0033 | 0.0012 | 0.0102 | 0.0037 | 0.0386 | 0.0208 | 0.0699 | 0.0357 | 0.0674 | 0.0386 | 0.0962 | 0.0530 | 0.7123 | 0.8467 | 0.0017 | 0.0038 | 0.0051 | 0.0091 | 0.0110 | 0.0152 | 0.0442 | 0.0800 | 0.1188 | 0.1523 | 0.1512 | 0.1789 | 0.1184 | 0.1144 | 0.1491 | 0.1413 | 0.4006 | 0.3050 | 0.0009 | 0.0013 | 0.0058 | 0.0245 | 0.0728 | 0.1185 | 0.1037 | 0.1302 | 0.5422 | 15 | 22 | 32 | 46 | 64 | 86 | 117 | 158 | 222 | 0.0165 | 11.29 | 5.277 | 0.4716 | 18511.3 | 5390000 | 2090000000 | 994000000000 | 0.5640 | 0.1104 | 0.0416 | 0.0021 | 0.1298 | 0.0145 | 0.2417 | 0.0717 | 0.1786 | 0.1322 | 0.1563 | 0.1705 | 0.1056 | 0.1818 | 0.0805 | 0.1400 | 0.0452 | 0.1272 | 0.0207 | 0.1600 | 0.0013 | 0.0006 | 0.0026 | 0.0025 | 0.0052 | 0.0043 | 0.0226 | 0.0158 | 0.0717 | 0.0537 | 0.1141 | 0.0969 | 0.0904 | 0.0786 | 0.1320 | 0.1170 | 0.5601 | 0.6307 | 0.0017 | 0.0015 | 0.0030 | 0.0031 | 0.0089 | 0.0133 | 0.0324 | 0.0402 | 0.0970 | 0.1132 | 0.1484 | 0.1592 | 0.1051 | 0.1113 | 0.1413 | 0.1490 | 0.4622 | 0.4093 | 0.0015 | 0.0038 | 0.0079 | 0.0238 | 0.0829 | 0.1287 | 0.1026 | 0.1362 | 0.5125 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 337 | 336 | | 436 | 1226 | 74.6 | 15.23 | 8.13 | 2.56 | 60 | 63 | 66 | 68 | 70 | 73 | 77 | 87 | 99 | 0.2047 | 251 | 1.186 | 32.02 | 11.05 | 1 | 0.1904 | 83 | 0.0637 | 1.09 | 3.210 | 0.6546 | 5802.3 | 471400 | 40100000 | 3560000000 | 0.4209 | 0.2111 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0159 | 0.0074 | 0.0349 | 0.0123 | 0.1111 | 0.0539 | 0.1714 | 0.1176 | 0.1270 | 0.1176 | 0.1302 | 0.1544 | 0.4095 | 0.5368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0069 | 0.0280 | 0.0115 | 0.0509 | 0.0413 | 0.0865 | 0.0894 | 0.0789 | 0.0642 | 0.0941 | 0.0917 | 0.6539 | 0.6950 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0128 | 0.1429 | 0.0641 | 0.2500 | 0.0897 | 0.2143 | 0.2821 | 0.1786 | 0.1282 | 0.1071 | 0.1154 | 0.0714 | 0.3077 | 0.0357 | 0.0134 | 0.0067 | 0.0000 | 0.0537 | 0.0872 | 0.1409 | 0.0940 | 0.1208 | 0.4832 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0165 | 10.44 | 4.481 | 0.3254 | 72.6 | 704.432 | 7374.94 | 83019.4 | 0.4958 | 0.1499 | 0.0199 | 0.0010 | 0.0634 | 0.0049 | 0.1793 | 0.0119 | 0.2500 | 0.0415 | 0.2591 | 0.0889 | 0.1612 | 0.1235 | 0.0562 | 0.2075 | 0.0091 | 0.3063 | 0.0018 | 0.2144 | 0.0011 | 0.0000 | 0.0103 | 0.0018 | 0.0411 | 0.0044 | 0.0959 | 0.0176 | 0.1610 | 0.0668 | 0.1826 | 0.0809 | 0.1724 | 0.1161 | 0.2226 | 0.2577 | 0.1130 | 0.4547 | 0.1204 | 0.2880 | 0.1821 | 0.2640 | 0.2006 | 0.1600 | 0.1728 | 0.1280 | 0.1512 | 0.0880 | 0.0895 | 0.0560 | 0.0525 | 0.0160 | 0.0278 | 0.0000 | 0.0031 | 0.0000 | 0.0118 | 0.0485 | 0.1132 | 0.1559 | 0.1529 | 0.1500 | 0.1853 | 0.1250 | 0.0574 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 422 | 387 | | 8367 | 21686 | 338.6 | 51.23 | 216.62 | 253.93 | 275 | 292 | 307 | 321 | 337 | 351 | 367 | 383 | 406 | 0.0592 | 1284 | 1.224 | 118.07 | 44.69 | 1 | 0.0354 | 296 | 0.0016 | 21.25 | 6.715 | 0.2518 | 117279.0 | 41500000 | 15000000000 | 5540000000000 | 0.4429 | 0.2078 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0080 | 0.0001 | 0.0305 | 0.0112 | 0.0543 | 0.0192 | 0.0664 | 0.0146 | 0.1150 | 0.0208 | 0.7238 | 0.9341 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0034 | 0.0000 | 0.0155 | 0.0105 | 0.0264 | 0.0169 | 0.0305 | 0.0096 | 0.0535 | 0.0147 | 0.8698 | 0.9484 | 0.0147 | 0.0000 | 0.0209 | 0.0000 | 0.0466 | 0.0000 | 0.0798 | 0.0000 | 0.1325 | 0.0000 | 0.1509 | 0.0000 | 0.1166 | 0.0000 | 0.1387 | 0.0000 | 0.2994 | 0.0000 | 0.0029 | 0.0037 | 0.0079 | 0.0179 | 0.0489 | 0.0872 | 0.0769 | 0.1138 | 0.6407 | 23 | 31 | 44 | 65 | 97 | 158 | 256 | 389 | 599 | 0.0168 | 30.30 | 6.006 | 0.4494 | 111401.0 | 80200000 | 68700000000 | 66100000000000 | 0.5043 | 0.1472 | 0.0237 | 0.0026 | 0.1369 | 0.0072 | 0.2565 | 0.0574 | 0.1751 | 0.1186 | 0.1568 | 0.1945 | 0.1196 | 0.2092 | 0.0501 | 0.1261 | 0.0356 | 0.1132 | 0.0458 | 0.1711 | 0.0002 | 0.0003 | 0.0005 | 0.0006 | 0.0022 | 0.0014 | 0.0105 | 0.0091 | 0.0514 | 0.0447 | 0.0911 | 0.0790 | 0.0565 | 0.0498 | 0.0825 | 0.0754 | 0.7050 | 0.7396 | 0.0003 | 0.0002 | 0.0011 | 0.0016 | 0.0023 | 0.0053 | 0.0156 | 0.0192 | 0.0627 | 0.0685 | 0.1061 | 0.1174 | 0.0749 | 0.0819 | 0.0955 | 0.0997 | 0.6414 | 0.6062 | 0.0001 | 0.0003 | 0.0026 | 0.0142 | 0.0598 | 0.0932 | 0.0668 | 0.0874 | 0.6756 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1087 | 911 | | 930 | 11171 | 100.7 | 22.55 | 6.80 | 4.19 | 73 | 79 | 86 | 93 | 99 | 105 | 111 | 121 | 133 | 0.0929 | 1038 | 1.197 | 26.91 | 10.82 | 2 | 0.0774 | 72 | 0.0206 | 2.16 | 4.113 | 0.5375 | 10648.5 | 1180000 | 137000000 | 16400000000 | 0.4115 | 0.2236 | 0.0018 | 0.0000 | 0.0037 | 0.0000 | 0.0147 | 0.0000 | 0.0403 | 0.0124 | 0.1007 | 0.0305 | 0.1941 | 0.0837 | 0.1905 | 0.0679 | 0.1978 | 0.1007 | 0.2564 | 0.7048 | 0.0014 | 0.0000 | 0.0027 | 0.0000 | 0.0041 | 0.0000 | 0.0192 | 0.0076 | 0.0426 | 0.0259 | 0.0852 | 0.0615 | 0.0742 | 0.0356 | 0.0989 | 0.0604 | 0.6717 | 0.8091 | 0.0000 | 0.0000 | 0.0549 | 0.0930 | 0.0275 | 0.1860 | 0.0769 | 0.1395 | 0.1593 | 0.1860 | 0.1538 | 0.1395 | 0.1209 | 0.1163 | 0.1209 | 0.0930 | 0.2857 | 0.0465 | 0.0023 | 0.0090 | 0.0248 | 0.0451 | 0.0858 | 0.1038 | 0.1264 | 0.1400 | 0.4628 | 3 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0170 | 13.34 | 4.491 | 0.3256 | 63.8 | 1717.75 | 142090 | 15800000 | 0.5342 | 0.1420 | 0.0158 | 0.0014 | 0.0687 | 0.0050 | 0.1509 | 0.0230 | 0.2289 | 0.0598 | 0.2453 | 0.1230 | 0.1792 | 0.2071 | 0.0851 | 0.2655 | 0.0242 | 0.2267 | 0.0020 | 0.0886 | 0.0031 | 0.0005 | 0.0114 | 0.0019 | 0.0454 | 0.0090 | 0.1019 | 0.0309 | 0.1665 | 0.0623 | 0.2143 | 0.1166 | 0.2056 | 0.2038 | 0.1486 | 0.2942 | 0.1033 | 0.2809 | 0.1680 | 0.3284 | 0.2346 | 0.2618 | 0.2091 | 0.1411 | 0.1446 | 0.0713 | 0.0657 | 0.0392 | 0.0481 | 0.0415 | 0.0308 | 0.0337 | 0.0460 | 0.0329 | 0.0530 | 0.0502 | 0.0170 | 0.0545 | 0.1103 | 0.1645 | 0.1904 | 0.1942 | 0.1363 | 0.0771 | 0.0558 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 658 | 168 | | 403 | 1766 | 68.5 | 19.76 | 7.99 | 2.37 | 49 | 53 | 56 | 59 | 63 | 70 | 74 | 85 | 98 | 0.1750 | 309 | 1.167 | 34.83 | 13.34 | 1 | 0.2258 | 91 | 0.0533 | 1.76 | 3.525 | 0.6505 | 5083.4 | 408505 | 35400000 | 3290000000 | 0.4186 | 0.2106 | 0.0050 | 0.0000 | 0.0347 | 0.0029 | 0.1139 | 0.0233 | 0.1139 | 0.0437 | 0.1386 | 0.0962 | 0.1238 | 0.1895 | 0.1386 | 0.1137 | 0.1238 | 0.1429 | 0.2079 | 0.3878 | 0.0034 | 0.0000 | 0.0103 | 0.0000 | 0.0206 | 0.0052 | 0.0412 | 0.0129 | 0.1237 | 0.0722 | 0.1340 | 0.1727 | 0.0790 | 0.0851 | 0.0962 | 0.1134 | 0.4914 | 0.5387 | 0.0112 | 0.0000 | 0.0112 | 0.0000 | 0.0000 | 0.0667 | 0.1236 | 0.2444 | 0.1685 | 0.2222 | 0.2360 | 0.2667 | 0.0787 | 0.0222 | 0.1461 | 0.0667 | 0.2247 | 0.1111 | 0.0000 | 0.0000 | 0.0117 | 0.0526 | 0.1287 | 0.1988 | 0.0877 | 0.1345 | 0.3860 | 5 | 6 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0170 | 10.27 | 4.413 | 0.3266 | 69.5 | 648.007 | 6410.02 | 66817.3 | 0.4806 | 0.1782 | 0.0225 | 0.0013 | 0.0688 | 0.0040 | 0.1865 | 0.0092 | 0.2678 | 0.0257 | 0.2240 | 0.0870 | 0.1502 | 0.1087 | 0.0601 | 0.1963 | 0.0138 | 0.3057 | 0.0063 | 0.2622 | 0.0049 | 0.0000 | 0.0154 | 0.0018 | 0.0561 | 0.0054 | 0.0829 | 0.0127 | 0.1488 | 0.0647 | 0.1715 | 0.0810 | 0.1837 | 0.0906 | 0.2179 | 0.2502 | 0.1187 | 0.4937 | 0.1230 | 0.3869 | 0.2181 | 0.2993 | 0.2645 | 0.1314 | 0.1763 | 0.1314 | 0.1137 | 0.0292 | 0.0650 | 0.0219 | 0.0232 | 0.0000 | 0.0139 | 0.0000 | 0.0023 | 0.0000 | 0.0089 | 0.0445 | 0.0870 | 0.1235 | 0.1966 | 0.2184 | 0.1601 | 0.1235 | 0.0375 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1203 | 196 | | 3608 | 1256 | 112.8 | 33.02 | 56.49 | 42.34 | 79 | 87 | 93 | 99 | 105 | 112 | 122 | 134 | 156 | 0.4076 | 512 | 0.975 | 95.35 | 33.06 | 2 | 0.0734 | 265 | 0.0032 | 16.99 | 6.143 | 0.2879 | 13822.0 | 1860000 | 276000000 | 45100000000 | 0.3979 | 0.2576 | 0.0010 | 0.0003 | 0.0065 | 0.0006 | 0.0176 | 0.0028 | 0.0391 | 0.0056 | 0.0918 | 0.0314 | 0.1565 | 0.0637 | 0.1590 | 0.0566 | 0.1951 | 0.0942 | 0.3335 | 0.7448 | 0.0004 | 0.0000 | 0.0026 | 0.0000 | 0.0097 | 0.0008 | 0.0164 | 0.0025 | 0.0421 | 0.0200 | 0.0742 | 0.0382 | 0.0753 | 0.0306 | 0.1037 | 0.0514 | 0.6755 | 0.8564 | 0.0102 | 0.0029 | 0.0116 | 0.0117 | 0.0277 | 0.0264 | 0.0524 | 0.0733 | 0.1252 | 0.1554 | 0.1514 | 0.1525 | 0.1208 | 0.1202 | 0.1339 | 0.1320 | 0.3668 | 0.3255 | 0.0035 | 0.0085 | 0.0148 | 0.0318 | 0.0890 | 0.1329 | 0.1025 | 0.1576 | 0.4594 | 20 | 26 | 31 | 37 | 45 | 55 | 65 | 79 | 102 | 0.0171 | 7.89 | 4.661 | 0.4707 | 4982.0 | 681992 | 133000000 | 33000000000 | 0.5597 | 0.0948 | 0.0435 | 0.0159 | 0.1268 | 0.0336 | 0.1739 | 0.0814 | 0.1775 | 0.1310 | 0.1920 | 0.1717 | 0.1522 | 0.1664 | 0.0942 | 0.1451 | 0.0254 | 0.1469 | 0.0145 | 0.1080 | 0.0016 | 0.0073 | 0.0126 | 0.0085 | 0.0316 | 0.0208 | 0.0411 | 0.0403 | 0.1785 | 0.1404 | 0.2054 | 0.2088 | 0.1627 | 0.1416 | 0.1769 | 0.1844 | 0.1896 | 0.2479 | 0.0056 | 0.0197 | 0.0364 | 0.0630 | 0.0756 | 0.0709 | 0.1064 | 0.1102 | 0.2269 | 0.2283 | 0.1961 | 0.1811 | 0.1064 | 0.1457 | 0.1457 | 0.1220 | 0.1008 | 0.0591 | 0.0021 | 0.0123 | 0.0452 | 0.0903 | 0.2074 | 0.2177 | 0.1561 | 0.1335 | 0.1355 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 895 | 228 | | 1426 | 7457 | 297.1 | 74.97 | 7.35 | 3.00 | 208 | 227 | 244 | 263 | 287 | 309 | 333 | 361 | 411 | 0.0758 | 565 | 1.060 | 52.39 | 17.09 | 1 | 0.0912 | 130 | 0.0050 | 5.81 | 5.550 | 0.3967 | 93879.8 | 31500000 | 11200000000 | 4160000000000 | 0.4025 | 0.2290 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0040 | 0.0008 | 0.0374 | 0.0038 | 0.0602 | 0.0369 | 0.0989 | 0.0638 | 0.0936 | 0.0430 | 0.1283 | 0.0692 | 0.5775 | 0.7809 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0171 | 0.0007 | 0.0286 | 0.0288 | 0.0390 | 0.0400 | 0.0448 | 0.0204 | 0.0524 | 0.0435 | 0.8171 | 0.8667 | 0.0000 | 0.0000 | 0.0066 | 0.0161 | 0.0166 | 0.0000 | 0.0364 | 0.0242 | 0.0530 | 0.1694 | 0.0629 | 0.1774 | 0.0927 | 0.0806 | 0.1060 | 0.2339 | 0.6258 | 0.2984 | 0.0016 | 0.0016 | 0.0109 | 0.0203 | 0.0422 | 0.0422 | 0.0703 | 0.0766 | 0.7344 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 11 | 0.0171 | 9.64 | 4.604 | 0.3424 | 63.0 | 623.07 | 7074.44 | 91176.4 | 0.4927 | 0.1584 | 0.0077 | 0.0045 | 0.0406 | 0.0095 | 0.0981 | 0.0305 | 0.1678 | 0.0652 | 0.2278 | 0.1209 | 0.2100 | 0.1971 | 0.1593 | 0.2556 | 0.0768 | 0.2221 | 0.0121 | 0.0947 | 0.0010 | 0.0002 | 0.0055 | 0.0018 | 0.0185 | 0.0077 | 0.0480 | 0.0279 | 0.0854 | 0.0599 | 0.1434 | 0.1145 | 0.1875 | 0.1703 | 0.2216 | 0.2463 | 0.2890 | 0.3715 | 0.1040 | 0.1438 | 0.1361 | 0.1222 | 0.1301 | 0.0872 | 0.0853 | 0.0745 | 0.0895 | 0.1058 | 0.0811 | 0.0857 | 0.0956 | 0.0842 | 0.0923 | 0.1170 | 0.1860 | 0.1796 | 0.0135 | 0.0521 | 0.0974 | 0.1372 | 0.1573 | 0.1377 | 0.1213 | 0.1143 | 0.1691 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 693 | | 1758 | 9747 | 194.5 | 65.03 | 7.39 | 2.56 | 126 | 140 | 153 | 164 | 173 | 189 | 216 | 254 | 297 | 0.0806 | 786 | 1.223 | 29.83 | 11.66 | 2 | 0.0438 | 77 | 0.0089 | 2.56 | 5.059 | 0.5219 | 42048.1 | 10100000 | 2640000000 | 742000000000 | 0.3576 | 0.2730 | 0.0013 | 0.0000 | 0.0053 | 0.0007 | 0.0093 | 0.0043 | 0.0200 | 0.0100 | 0.0787 | 0.0400 | 0.1267 | 0.0557 | 0.1067 | 0.0550 | 0.1440 | 0.0764 | 0.5080 | 0.7580 | 0.0008 | 0.0000 | 0.0034 | 0.0006 | 0.0050 | 0.0024 | 0.0101 | 0.0078 | 0.0378 | 0.0269 | 0.0512 | 0.0305 | 0.0419 | 0.0335 | 0.0680 | 0.0449 | 0.7819 | 0.8533 | 0.0023 | 0.0037 | 0.0000 | 0.0037 | 0.0000 | 0.0000 | 0.0090 | 0.0186 | 0.0498 | 0.0520 | 0.0611 | 0.0892 | 0.0452 | 0.0520 | 0.0656 | 0.0743 | 0.7670 | 0.7063 | 0.0000 | 0.0000 | 0.0030 | 0.0076 | 0.0318 | 0.0636 | 0.0394 | 0.0561 | 0.7985 | 4 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0172 | 8.20 | 4.461 | 0.3585 | 61.1 | 562.508 | 5723.84 | 64032.1 | 0.4837 | 0.1687 | 0.0143 | 0.0020 | 0.0491 | 0.0072 | 0.1154 | 0.0186 | 0.1968 | 0.0459 | 0.2244 | 0.0938 | 0.2015 | 0.1724 | 0.1356 | 0.2637 | 0.0542 | 0.2652 | 0.0087 | 0.1312 | 0.0012 | 0.0000 | 0.0093 | 0.0006 | 0.0270 | 0.0038 | 0.0627 | 0.0130 | 0.1007 | 0.0342 | 0.1357 | 0.0750 | 0.1749 | 0.1500 | 0.2022 | 0.2720 | 0.2862 | 0.4515 | 0.1173 | 0.1778 | 0.1454 | 0.1541 | 0.1396 | 0.1171 | 0.1150 | 0.1141 | 0.1015 | 0.0801 | 0.0904 | 0.0898 | 0.0869 | 0.0746 | 0.0800 | 0.0728 | 0.1238 | 0.1195 | 0.0077 | 0.0301 | 0.0649 | 0.1143 | 0.1463 | 0.1559 | 0.1546 | 0.1313 | 0.1950 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 118 | 70 | | 1754 | 4174 | 82.7 | 19.21 | 183.51 | 192.01 | 60 | 66 | 71 | 76 | 81 | 86 | 92 | 98 | 108 | 0.1445 | 603 | 0.362 | 172.26 | 45.00 | 1 | 0.4025 | 706 | 0.0023 | 27.82 | 6.291 | 0.2092 | 7207.4 | 660678 | 63600000 | 6400000000 | 0.4497 | 0.1988 | 0.0009 | 0.0000 | 0.0066 | 0.0000 | 0.0161 | 0.0031 | 0.0530 | 0.0093 | 0.1258 | 0.0322 | 0.1542 | 0.0811 | 0.1987 | 0.0619 | 0.2271 | 0.1002 | 0.2176 | 0.7123 | 0.0000 | 0.0000 | 0.0036 | 0.0000 | 0.0065 | 0.0017 | 0.0210 | 0.0035 | 0.0564 | 0.0239 | 0.0694 | 0.0554 | 0.0845 | 0.0309 | 0.1185 | 0.0612 | 0.6402 | 0.8233 | 0.0183 | 0.0101 | 0.0367 | 0.0202 | 0.0765 | 0.0808 | 0.1009 | 0.2121 | 0.1407 | 0.2323 | 0.1529 | 0.2222 | 0.1315 | 0.0909 | 0.1070 | 0.0909 | 0.2355 | 0.0404 | 0.0024 | 0.0120 | 0.0240 | 0.0456 | 0.0948 | 0.1116 | 0.1273 | 0.1645 | 0.4178 | 24 | 30 | 42 | 62 | 105 | 161 | 244 | 333 | 444 | 0.0173 | 43.47 | 5.837 | 0.3746 | 70533.6 | 37800000 | 24900000000 | 19100000000000 | 0.4742 | 0.1698 | 0.1259 | 0.0058 | 0.2370 | 0.0559 | 0.2840 | 0.2328 | 0.1457 | 0.1420 | 0.0889 | 0.1700 | 0.0617 | 0.1455 | 0.0420 | 0.0873 | 0.0099 | 0.0733 | 0.0049 | 0.0873 | 0.0011 | 0.0010 | 0.0028 | 0.0020 | 0.0091 | 0.0024 | 0.0300 | 0.0215 | 0.0935 | 0.0842 | 0.1230 | 0.1214 | 0.0941 | 0.0773 | 0.1423 | 0.1214 | 0.5040 | 0.5688 | 0.0007 | 0.0000 | 0.0059 | 0.0051 | 0.0074 | 0.0144 | 0.0368 | 0.0405 | 0.1177 | 0.1267 | 0.1575 | 0.1976 | 0.1302 | 0.1351 | 0.1707 | 0.1520 | 0.3731 | 0.3285 | 0.0013 | 0.0026 | 0.0059 | 0.0300 | 0.1019 | 0.1457 | 0.1130 | 0.1470 | 0.4526 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 845 | 391 | | 8714 | 28501 | 282.2 | 64.28 | 121.16 | 121.03 | 206 | 227 | 243 | 259 | 276 | 293 | 313 | 334 | 368 | 0.0454 | 1293 | 1.148 | 102.08 | 30.46 | 1 | 0.0270 | 235 | 0.0023 | 14.79 | 6.394 | 0.2854 | 83742.3 | 26100000 | 8530000000 | 2910000000000 | 0.4516 | 0.1999 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0048 | 0.0004 | 0.0140 | 0.0014 | 0.0658 | 0.0182 | 0.1361 | 0.0403 | 0.1469 | 0.0472 | 0.1796 | 0.0612 | 0.4515 | 0.8313 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0002 | 0.0057 | 0.0007 | 0.0319 | 0.0118 | 0.0595 | 0.0218 | 0.0612 | 0.0237 | 0.0824 | 0.0326 | 0.7570 | 0.9091 | 0.0044 | 0.0000 | 0.0062 | 0.0143 | 0.0187 | 0.0531 | 0.0704 | 0.0755 | 0.1172 | 0.1633 | 0.1509 | 0.2286 | 0.1010 | 0.0857 | 0.1415 | 0.1429 | 0.3897 | 0.2367 | 0.0005 | 0.0007 | 0.0074 | 0.0253 | 0.0763 | 0.1144 | 0.0817 | 0.1207 | 0.5730 | 16 | 28 | 45 | 64 | 86 | 111 | 142 | 189 | 270 | 0.0173 | 10.15 | 5.255 | 0.4896 | 29326.3 | 11100000 | 5770000000 | 3740000000000 | 0.5092 | 0.1670 | 0.0151 | 0.0015 | 0.0740 | 0.0061 | 0.1650 | 0.0287 | 0.1715 | 0.0720 | 0.1760 | 0.1555 | 0.1560 | 0.1872 | 0.1115 | 0.1505 | 0.0848 | 0.1481 | 0.0462 | 0.2505 | 0.0002 | 0.0005 | 0.0014 | 0.0011 | 0.0052 | 0.0033 | 0.0204 | 0.0126 | 0.0607 | 0.0488 | 0.0975 | 0.0843 | 0.0811 | 0.0687 | 0.1062 | 0.0968 | 0.6273 | 0.6839 | 0.0018 | 0.0015 | 0.0029 | 0.0027 | 0.0062 | 0.0087 | 0.0255 | 0.0332 | 0.0815 | 0.0912 | 0.1277 | 0.1335 | 0.0916 | 0.0982 | 0.1235 | 0.1301 | 0.5393 | 0.5010 | 0.0013 | 0.0021 | 0.0052 | 0.0239 | 0.0719 | 0.1113 | 0.0898 | 0.1163 | 0.5781 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 844 | | 2908 | 15413 | 16.0 | 5.68 | 6.17 | 2.21 | 10 | 12 | 13 | 14 | 15 | 16 | 18 | 19 | 22 | 0.0804 | 1239 | 1.278 | 24.04 | 7.81 | 0 | 0.0193 | 56 | 0.0081 | 8.98 | 5.211 | 0.3653 | 289.8 | 6020.69 | 146883 | 4220000 | 0.4199 | 0.2102 | 0.0085 | 0.0004 | 0.0216 | 0.0036 | 0.0385 | 0.0085 | 0.0745 | 0.0222 | 0.1137 | 0.0287 | 0.1476 | 0.0534 | 0.2149 | 0.0825 | 0.2097 | 0.1756 | 0.1711 | 0.6250 | 0.0052 | 0.0000 | 0.0124 | 0.0018 | 0.0204 | 0.0040 | 0.0261 | 0.0141 | 0.0461 | 0.0196 | 0.0518 | 0.0236 | 0.0969 | 0.0460 | 0.1330 | 0.0873 | 0.6081 | 0.8036 | 0.0279 | 0.0590 | 0.0540 | 0.0729 | 0.0714 | 0.0521 | 0.0976 | 0.0486 | 0.1063 | 0.0972 | 0.0871 | 0.1632 | 0.1080 | 0.1042 | 0.1307 | 0.1250 | 0.3171 | 0.2778 | 0.0127 | 0.0202 | 0.0254 | 0.0419 | 0.0538 | 0.0695 | 0.1046 | 0.1674 | 0.5045 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0174 | 10.89 | 4.353 | 0.3184 | 42.9 | 326.59 | 2675.72 | 23343.4 | 0.5105 | 0.1490 | 0.0093 | 0.0007 | 0.0467 | 0.0029 | 0.1332 | 0.0168 | 0.2261 | 0.0557 | 0.2649 | 0.1187 | 0.2015 | 0.1957 | 0.0932 | 0.2556 | 0.0225 | 0.2405 | 0.0026 | 0.1134 | 0.0005 | 0.0000 | 0.0014 | 0.0005 | 0.0117 | 0.0029 | 0.0395 | 0.0124 | 0.0975 | 0.0337 | 0.1985 | 0.0723 | 0.2678 | 0.1849 | 0.2578 | 0.3562 | 0.1253 | 0.3371 | 0.1026 | 0.2983 | 0.2437 | 0.3365 | 0.2794 | 0.2278 | 0.2269 | 0.0988 | 0.1028 | 0.0292 | 0.0369 | 0.0090 | 0.0071 | 0.0004 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0196 | 0.0575 | 0.1217 | 0.1919 | 0.2514 | 0.2092 | 0.1174 | 0.0298 |
| SK-BR-3 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 961 | 83 | | 2742 | 10295 | 256.4 | 210.99 | 5.84 | 2.73 | 85 | 107 | 125 | 146 | 174 | 205 | 260 | 375 | 620 | 0.0768 | 791 | 0.892 | 36.22 | 8.60 | 0 | 0.0317 | 87 | 0.0014 | 48.21 | 6.944 | 0.2535 | 110231.0 | 65700000 | 45700000000 | 34200000000000 | 0.3023 | 0.3121 | 0.0000 | 0.0000 | 0.0068 | 0.0000 | 0.0091 | 0.0000 | 0.0590 | 0.0149 | 0.1791 | 0.0528 | 0.1655 | 0.0916 | 0.1179 | 0.0677 | 0.1088 | 0.1066 | 0.3537 | 0.6663 | 0.0000 | 0.0000 | 0.0027 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0076 | 0.0370 | 0.0242 | 0.0497 | 0.0369 | 0.0416 | 0.0242 | 0.0542 | 0.0445 | 0.8076 | 0.8626 | 0.0015 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0075 | 0.0070 | 0.0330 | 0.0370 | 0.0526 | 0.0546 | 0.0330 | 0.0352 | 0.0691 | 0.0651 | 0.8018 | 0.8011 | 0.0012 | 0.0012 | 0.0000 | 0.0059 | 0.0297 | 0.0547 | 0.0321 | 0.0523 | 0.8228 | 2 | 4 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 0.0175 | 13.89 | 4.460 | 0.2950 | 41.5 | 339.783 | 3128.09 | 31961.6 | 0.5476 | 0.1416 | 0.0210 | 0.0022 | 0.0924 | 0.0062 | 0.1853 | 0.0333 | 0.2319 | 0.0823 | 0.2233 | 0.1544 | 0.1561 | 0.2425 | 0.0700 | 0.2497 | 0.0170 | 0.1701 | 0.0030 | 0.0593 | 0.0012 | 0.0000 | 0.0080 | 0.0010 | 0.0371 | 0.0068 | 0.0981 | 0.0266 | 0.1836 | 0.0573 | 0.2370 | 0.1201 | 0.2176 | 0.2178 | 0.1428 | 0.3119 | 0.0746 | 0.2586 | 0.1311 | 0.2667 | 0.2100 | 0.2515 | 0.2092 | 0.1673 | 0.1698 | 0.1115 | 0.1054 | 0.0630 | 0.0671 | 0.0527 | 0.0519 | 0.0333 | 0.0371 | 0.0339 | 0.0183 | 0.0200 | 0.0124 | 0.0502 | 0.1000 | 0.1483 | 0.1892 | 0.1839 | 0.1558 | 0.0989 | 0.0613 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 244 | 404 | | 494 | 2485 | 92.6 | 12.71 | 8.21 | 2.59 | 77 | 82 | 85 | 87 | 91 | 94 | 99 | 105 | 111 | 0.1469 | 365 | 1.264 | 23.35 | 8.54 | 2 | 0.1215 | 60 | 0.0560 | 0.95 | 3.137 | 0.6794 | 8731.3 | 838707 | 82000000 | 8150000000 | 0.3994 | 0.2357 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0071 | 0.0000 | 0.0165 | 0.0020 | 0.0615 | 0.0405 | 0.1229 | 0.0749 | 0.0827 | 0.0283 | 0.1348 | 0.0445 | 0.5745 | 0.8097 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0020 | 0.0404 | 0.0405 | 0.0702 | 0.0749 | 0.0319 | 0.0283 | 0.0574 | 0.0445 | 0.7915 | 0.8097 | 0.0000 | 0.0000 | 0.0851 | 0.0000 | 0.1277 | 0.0000 | 0.1915 | 0.0000 | 0.2128 | 0.0000 | 0.1702 | 0.0000 | 0.1064 | 0.0000 | 0.1064 | 0.0000 | 0.0000 | 0.0000 | 0.0089 | 0.0133 | 0.0089 | 0.0356 | 0.0667 | 0.0889 | 0.0933 | 0.1200 | 0.5644 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0177 | 10.75 | 4.510 | 0.3406 | 74.1 | 727.275 | 7718.61 | 88127.3 | 0.5118 | 0.1497 | 0.0233 | 0.0000 | 0.0933 | 0.0043 | 0.1707 | 0.0071 | 0.2341 | 0.0331 | 0.2211 | 0.0576 | 0.1763 | 0.0997 | 0.0606 | 0.1790 | 0.0187 | 0.3226 | 0.0019 | 0.2966 | 0.0017 | 0.0000 | 0.0207 | 0.0013 | 0.0407 | 0.0030 | 0.0878 | 0.0127 | 0.1228 | 0.0348 | 0.1641 | 0.0556 | 0.1922 | 0.0824 | 0.1876 | 0.2238 | 0.1824 | 0.5864 | 0.1028 | 0.2563 | 0.1416 | 0.2059 | 0.1490 | 0.1681 | 0.1714 | 0.1261 | 0.1222 | 0.1176 | 0.1386 | 0.0588 | 0.1073 | 0.0504 | 0.0566 | 0.0168 | 0.0104 | 0.0000 | 0.0115 | 0.0413 | 0.0678 | 0.1287 | 0.1430 | 0.1714 | 0.1850 | 0.1558 | 0.0955 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 508 | 386 | | 1856 | 6121 | 930.2 | 328.29 | 7.48 | 2.44 | 554 | 653 | 741 | 809 | 938 | 1045 | 1136 | 1227 | 1377 | 0.0853 | 522 | 1.026 | 43.86 | 14.14 | 1 | 0.0641 | 119 | 0.0008 | 115.28 | 7.271 | 0.1207 | 972996.0 | 1100000000 | 1310000000000 | 1.62E+15 | 0.4447 | 0.1728 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0173 | 0.0007 | 0.0317 | 0.0064 | 0.1400 | 0.0443 | 0.2107 | 0.1180 | 0.1486 | 0.0730 | 0.1962 | 0.1001 | 0.2554 | 0.6574 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0006 | 0.0093 | 0.0030 | 0.0388 | 0.0270 | 0.0705 | 0.0642 | 0.0496 | 0.0354 | 0.0659 | 0.0564 | 0.7651 | 0.8134 | 0.0034 | 0.0000 | 0.0000 | 0.0074 | 0.0000 | 0.0037 | 0.0201 | 0.0260 | 0.0586 | 0.1078 | 0.1273 | 0.1933 | 0.0771 | 0.0818 | 0.1039 | 0.0855 | 0.6097 | 0.4944 | 0.0000 | 0.0000 | 0.0000 | 0.0053 | 0.0427 | 0.0907 | 0.0491 | 0.0768 | 0.7353 | 5 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0178 | 7.81 | 4.411 | 0.3613 | 61.9 | 562.793 | 5603.58 | 60707.4 | 0.4721 | 0.1687 | 0.0133 | 0.0031 | 0.0511 | 0.0061 | 0.1011 | 0.0157 | 0.1867 | 0.0367 | 0.2357 | 0.0887 | 0.1933 | 0.1507 | 0.1532 | 0.2219 | 0.0544 | 0.2907 | 0.0113 | 0.1863 | 0.0006 | 0.0000 | 0.0046 | 0.0003 | 0.0191 | 0.0016 | 0.0469 | 0.0087 | 0.0879 | 0.0304 | 0.1387 | 0.0535 | 0.1808 | 0.0957 | 0.2333 | 0.2328 | 0.2882 | 0.5769 | 0.0957 | 0.1536 | 0.1428 | 0.1826 | 0.1400 | 0.1273 | 0.1328 | 0.0834 | 0.1079 | 0.0869 | 0.1063 | 0.0860 | 0.0847 | 0.0808 | 0.0841 | 0.0939 | 0.1057 | 0.1054 | 0.0056 | 0.0360 | 0.0685 | 0.1045 | 0.1391 | 0.1650 | 0.1550 | 0.1468 | 0.1796 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1223 | 452 | | 6155 | 9803 | 128.7 | 28.06 | 148.51 | 137.13 | 95 | 105 | 112 | 119 | 126 | 133 | 141 | 152 | 166 | 0.0870 | 853 | 0.535 | 195.17 | 41.62 | 2 | 0.0980 | 603 | 0.0012 | 37.11 | 6.972 | 0.1989 | 17339.8 | 2450000 | 361000000 | 55800000000 | 0.4378 | 0.2119 | 0.0003 | 0.0000 | 0.0015 | 0.0000 | 0.0054 | 0.0000 | 0.0219 | 0.0026 | 0.0706 | 0.0184 | 0.1443 | 0.0426 | 0.1512 | 0.0447 | 0.1856 | 0.0693 | 0.4192 | 0.8224 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0022 | 0.0000 | 0.0078 | 0.0007 | 0.0301 | 0.0139 | 0.0603 | 0.0269 | 0.0630 | 0.0203 | 0.0920 | 0.0328 | 0.7436 | 0.9054 | 0.0055 | 0.0231 | 0.0156 | 0.0423 | 0.0294 | 0.1000 | 0.0725 | 0.1577 | 0.1330 | 0.1577 | 0.1982 | 0.1731 | 0.1330 | 0.1269 | 0.1450 | 0.0885 | 0.2679 | 0.1308 | 0.0021 | 0.0067 | 0.0102 | 0.0376 | 0.0709 | 0.1254 | 0.1180 | 0.1394 | 0.4898 | 14 | 24 | 55 | 81 | 109 | 144 | 187 | 247 | 346 | 0.0183 | 16.97 | 5.620 | 0.4458 | 40857.3 | 15200000 | 6830000000 | 3500000000000 | 0.6750 | 0.0565 | 0.0233 | 0.0013 | 0.1047 | 0.0122 | 0.2115 | 0.0411 | 0.1937 | 0.0746 | 0.1814 | 0.1677 | 0.1513 | 0.1982 | 0.0767 | 0.1700 | 0.0431 | 0.1519 | 0.0144 | 0.1831 | 0.0004 | 0.0005 | 0.0002 | 0.0013 | 0.0026 | 0.0023 | 0.0199 | 0.0116 | 0.0656 | 0.0497 | 0.1179 | 0.0886 | 0.0905 | 0.0744 | 0.1297 | 0.1150 | 0.5731 | 0.6565 | 0.0000 | 0.0012 | 0.0016 | 0.0051 | 0.0090 | 0.0086 | 0.0347 | 0.0451 | 0.1006 | 0.1221 | 0.1546 | 0.1495 | 0.1060 | 0.1197 | 0.1375 | 0.1436 | 0.4560 | 0.4050 | 0.0003 | 0.0016 | 0.0047 | 0.0229 | 0.0938 | 0.1286 | 0.0967 | 0.1442 | 0.5071 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 923 | 749 | | 18485 | 19144 | 337.4 | 48.91 | 148.53 | 162.19 | 268 | 300 | 318 | 331 | 344 | 355 | 367 | 380 | 396 | 0.0705 | 1349 | 1.142 | 100.72 | 39.20 | 2 | 0.0147 | 271 | 0.0025 | 9.90 | 6.327 | 0.3429 | 116234.0 | 40800000 | 14500000000 | 5230000000000 | 0.4218 | 0.2181 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0027 | 0.0001 | 0.0083 | 0.0008 | 0.0174 | 0.0071 | 0.0285 | 0.0145 | 0.0316 | 0.0074 | 0.0551 | 0.0119 | 0.8546 | 0.9581 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0001 | 0.0022 | 0.0008 | 0.0085 | 0.0071 | 0.0136 | 0.0145 | 0.0122 | 0.0074 | 0.0186 | 0.0119 | 0.9443 | 0.9581 | 0.0326 | 0.0000 | 0.0692 | 0.0000 | 0.0794 | 0.0000 | 0.1090 | 0.0000 | 0.1517 | 0.0000 | 0.1415 | 0.0000 | 0.1395 | 0.0000 | 0.1446 | 0.0000 | 0.1324 | 0.0000 | 0.0028 | 0.0050 | 0.0091 | 0.0138 | 0.0293 | 0.0412 | 0.0457 | 0.0737 | 0.7793 | 23 | 31 | 42 | 57 | 77 | 109 | 167 | 256 | 387 | 0.0183 | 13.36 | 5.441 | 0.5104 | 48364.8 | 22700000 | 12800000000 | 8140000000000 | 0.3890 | 0.2609 | 0.0233 | 0.0013 | 0.0952 | 0.0085 | 0.1700 | 0.0530 | 0.1578 | 0.1011 | 0.1966 | 0.1512 | 0.1445 | 0.1702 | 0.0908 | 0.1386 | 0.0714 | 0.1404 | 0.0504 | 0.2358 | 0.0001 | 0.0003 | 0.0008 | 0.0009 | 0.0026 | 0.0044 | 0.0128 | 0.0124 | 0.0492 | 0.0417 | 0.0708 | 0.0661 | 0.0547 | 0.0448 | 0.0827 | 0.0706 | 0.7262 | 0.7587 | 0.0007 | 0.0006 | 0.0009 | 0.0017 | 0.0035 | 0.0058 | 0.0196 | 0.0235 | 0.0581 | 0.0707 | 0.0989 | 0.0946 | 0.0629 | 0.0773 | 0.0941 | 0.1006 | 0.6612 | 0.6252 | 0.0000 | 0.0010 | 0.0043 | 0.0159 | 0.0522 | 0.0864 | 0.0570 | 0.0870 | 0.6963 |