High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 854 | 856 | | 7221 | 14570 | 49.4 | 17.53 | 78.00 | 136.28 | 28 | 34 | 38 | 43 | 47 | 52 | 58 | 64 | 73 | 0.0925 | 1347 | 0.564 | 226.82 | 39.32 | 13 | 0.0867 | 626 | 0.0060 | 6.82 | 5.419 | 0.3768 | 2746.4 | 169000 | 11300000 | 819000000 | 0.4385 | 0.1979 | 0.0021 | 0.0002 | 0.0092 | 0.0013 | 0.0509 | 0.0036 | 0.1206 | 0.0209 | 0.1835 | 0.0519 | 0.1998 | 0.1171 | 0.1729 | 0.1192 | 0.1266 | 0.1517 | 0.1344 | 0.5342 | 0.0004 | 0.0000 | 0.0012 | 0.0005 | 0.0037 | 0.0013 | 0.0217 | 0.0112 | 0.0562 | 0.0266 | 0.0864 | 0.0540 | 0.0848 | 0.0579 | 0.1085 | 0.0691 | 0.6371 | 0.7796 | 0.0039 | 0.0097 | 0.0073 | 0.0154 | 0.0194 | 0.0328 | 0.0682 | 0.0936 | 0.1094 | 0.1380 | 0.1510 | 0.1979 | 0.1292 | 0.1342 | 0.1549 | 0.1467 | 0.3567 | 0.2317 | 0.0017 | 0.0026 | 0.0125 | 0.0408 | 0.0755 | 0.1098 | 0.1078 | 0.1329 | 0.5163 | 11 | 13 | 15 | 17 | 20 | 26 | 46 | 104 | 234 | 0.1860 | 10.58 | 3.510 | 0.6862 | 24655.2 | 13200000 | 8940000000 | 7000000000000 | 0.6410 | 0.1101 | 0.1548 | 0.0039 | 0.3289 | 0.0394 | 0.2946 | 0.2229 | 0.1131 | 0.2327 | 0.0565 | 0.2189 | 0.0298 | 0.1433 | 0.0134 | 0.0671 | 0.0074 | 0.0493 | 0.0015 | 0.0224 | 0.0008 | 0.0002 | 0.0008 | 0.0005 | 0.0032 | 0.0053 | 0.0201 | 0.0138 | 0.0823 | 0.0766 | 0.1173 | 0.0994 | 0.0839 | 0.0713 | 0.1284 | 0.1266 | 0.5631 | 0.6063 | 0.0003 | 0.0007 | 0.0023 | 0.0021 | 0.0058 | 0.0053 | 0.0229 | 0.0248 | 0.1011 | 0.1076 | 0.1308 | 0.1522 | 0.0995 | 0.0995 | 0.1485 | 0.1501 | 0.4889 | 0.4577 | 0.0000 | 0.0023 | 0.0053 | 0.0197 | 0.0978 | 0.1169 | 0.0934 | 0.1436 | 0.5211 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 771 | 729 | | 699 | 8074 | 51.0 | 15.12 | 134.99 | 188.23 | 31 | 35 | 40 | 45 | 50 | 56 | 62 | 67 | 72 | 0.0588 | 475 | 1.025 | 40.01 | 10.20 | 1 | 0.1373 | 96 | 0.0059 | 6.82 | 5.319 | 0.3605 | 2826.1 | 167621 | 10500000 | 678000000 | 0.3593 | 0.2671 | 0.0074 | 0.0000 | 0.0223 | 0.0106 | 0.0186 | 0.0195 | 0.0483 | 0.0283 | 0.1264 | 0.0496 | 0.1561 | 0.0637 | 0.1822 | 0.0991 | 0.2119 | 0.1558 | 0.2268 | 0.5735 | 0.0000 | 0.0000 | 0.0021 | 0.0016 | 0.0021 | 0.0094 | 0.0125 | 0.0141 | 0.0480 | 0.0297 | 0.0438 | 0.0375 | 0.0438 | 0.0531 | 0.0710 | 0.0688 | 0.7766 | 0.7859 | 0.0000 | 0.0267 | 0.0095 | 0.0533 | 0.0095 | 0.0533 | 0.0714 | 0.1867 | 0.0571 | 0.1333 | 0.0857 | 0.2000 | 0.1333 | 0.1733 | 0.1762 | 0.1467 | 0.4571 | 0.0267 | 0.0000 | 0.0029 | 0.0086 | 0.0201 | 0.0430 | 0.0630 | 0.0516 | 0.0860 | 0.7249 | 17 | 20 | 22 | 27 | 42 | 69 | 121 | 231 | 414 | 0.1036 | 10.05 | 4.238 | 0.6273 | 53649.5 | 30800000 | 20700000000 | 15500000000000 | 0.6068 | 0.0942 | 0.0493 | 0.0037 | 0.1637 | 0.0266 | 0.2249 | 0.1322 | 0.1657 | 0.1506 | 0.1400 | 0.1304 | 0.1183 | 0.1680 | 0.0552 | 0.1074 | 0.0414 | 0.0973 | 0.0414 | 0.1837 | 0.0004 | 0.0007 | 0.0012 | 0.0013 | 0.0046 | 0.0030 | 0.0150 | 0.0167 | 0.0547 | 0.0407 | 0.0875 | 0.0781 | 0.0586 | 0.0524 | 0.0848 | 0.0851 | 0.6933 | 0.7219 | 0.0005 | 0.0005 | 0.0019 | 0.0042 | 0.0043 | 0.0100 | 0.0168 | 0.0173 | 0.0570 | 0.0614 | 0.1049 | 0.0992 | 0.0608 | 0.0719 | 0.0967 | 0.1028 | 0.6571 | 0.6327 | 0.0000 | 0.0039 | 0.0035 | 0.0195 | 0.0500 | 0.0925 | 0.0626 | 0.0947 | 0.6733 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1069 | 128 | | 2783 | 11256 | 51.7 | 18.54 | 103.66 | 116.84 | 30 | 35 | 40 | 45 | 50 | 54 | 60 | 67 | 78 | 0.0861 | 969 | 0.603 | 152.75 | 27.51 | 6 | 0.1347 | 375 | 0.0052 | 9.08 | 5.547 | 0.3491 | 3018.8 | 195743 | 13900000 | 1050000000 | 0.4330 | 0.1802 | 0.0026 | 0.0005 | 0.0071 | 0.0000 | 0.0556 | 0.0035 | 0.1412 | 0.0262 | 0.1571 | 0.0657 | 0.1986 | 0.1226 | 0.1297 | 0.1409 | 0.1262 | 0.1557 | 0.1818 | 0.4849 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0011 | 0.0017 | 0.0228 | 0.0132 | 0.0565 | 0.0405 | 0.1146 | 0.0653 | 0.0880 | 0.0690 | 0.1222 | 0.0860 | 0.5932 | 0.7243 | 0.0071 | 0.0025 | 0.0085 | 0.0354 | 0.0297 | 0.0303 | 0.0621 | 0.0581 | 0.1285 | 0.1465 | 0.1370 | 0.1641 | 0.1314 | 0.1237 | 0.1427 | 0.1717 | 0.3531 | 0.2677 | 0.0008 | 0.0000 | 0.0110 | 0.0432 | 0.0856 | 0.1540 | 0.1163 | 0.1406 | 0.4485 | 13 | 17 | 24 | 38 | 58 | 83 | 121 | 176 | 261 | 0.0237 | 15.67 | 5.256 | 0.4584 | 24394.3 | 8520000 | 3730000000 | 1900000000000 | 0.5135 | 0.1676 | 0.0460 | 0.0031 | 0.1957 | 0.0140 | 0.2492 | 0.0815 | 0.1672 | 0.1444 | 0.1530 | 0.1870 | 0.0962 | 0.1917 | 0.0552 | 0.1269 | 0.0268 | 0.1211 | 0.0109 | 0.1304 | 0.0004 | 0.0007 | 0.0020 | 0.0011 | 0.0080 | 0.0037 | 0.0214 | 0.0182 | 0.0764 | 0.0588 | 0.1256 | 0.1088 | 0.0857 | 0.0785 | 0.1129 | 0.1069 | 0.5677 | 0.6232 | 0.0021 | 0.0004 | 0.0030 | 0.0071 | 0.0118 | 0.0139 | 0.0300 | 0.0363 | 0.0919 | 0.0879 | 0.1475 | 0.1584 | 0.1001 | 0.0993 | 0.1186 | 0.1217 | 0.4948 | 0.4751 | 0.0005 | 0.0031 | 0.0065 | 0.0265 | 0.0749 | 0.1471 | 0.0884 | 0.1191 | 0.5339 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 688 | 317 | | 634 | 1912 | 61.1 | 11.51 | 6.65 | 2.29 | 51 | 53 | 55 | 57 | 59 | 62 | 64 | 67 | 72 | 0.1815 | 347 | 0.352 | 32.70 | 5.39 | 1 | 0.1893 | 120 | 0.1030 | 0.83 | 2.651 | 0.7146 | 3861.0 | 255798 | 18100000 | 1380000000 | 0.3514 | 0.2723 | 0.0000 | 0.0000 | 0.0055 | 0.0000 | 0.0147 | 0.0049 | 0.0257 | 0.0180 | 0.0754 | 0.0377 | 0.1471 | 0.1361 | 0.0901 | 0.0656 | 0.1746 | 0.0885 | 0.4669 | 0.6492 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0117 | 0.0016 | 0.0167 | 0.0126 | 0.0552 | 0.0379 | 0.1154 | 0.1183 | 0.0635 | 0.0473 | 0.1338 | 0.0804 | 0.6020 | 0.7019 | 0.0185 | 0.0000 | 0.0000 | 0.0000 | 0.1111 | 0.0000 | 0.0741 | 0.2500 | 0.1852 | 0.1667 | 0.1852 | 0.3333 | 0.1111 | 0.0000 | 0.0741 | 0.0833 | 0.2407 | 0.1667 | 0.0071 | 0.0179 | 0.0214 | 0.0750 | 0.1571 | 0.1607 | 0.1750 | 0.1321 | 0.2536 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 8 | 10 | 0.0192 | 7.74 | 4.309 | 0.3727 | 49.5 | 405.119 | 3603.71 | 34564.2 | 0.5192 | 0.1236 | 0.0276 | 0.0014 | 0.1166 | 0.0113 | 0.1899 | 0.0346 | 0.2067 | 0.0720 | 0.2067 | 0.1200 | 0.1322 | 0.1962 | 0.0745 | 0.2392 | 0.0397 | 0.2188 | 0.0060 | 0.1066 | 0.0107 | 0.0006 | 0.0471 | 0.0074 | 0.0661 | 0.0135 | 0.1033 | 0.0418 | 0.1281 | 0.0811 | 0.1702 | 0.1345 | 0.1860 | 0.1499 | 0.1570 | 0.2500 | 0.1314 | 0.3213 | 0.1296 | 0.2038 | 0.1640 | 0.2464 | 0.2275 | 0.2512 | 0.1772 | 0.1706 | 0.1296 | 0.0569 | 0.1032 | 0.0474 | 0.0423 | 0.0237 | 0.0265 | 0.0000 | 0.0000 | 0.0000 | 0.0322 | 0.0665 | 0.1104 | 0.1179 | 0.1533 | 0.1608 | 0.1554 | 0.1222 | 0.0815 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 684 | 361 | | 399 | 6206 | 58.4 | 9.74 | 24.73 | 66.86 | 46 | 49 | 52 | 54 | 57 | 61 | 64 | 69 | 72 | 0.1017 | 631 | 0.682 | 36.24 | 8.54 | 1 | 0.2607 | 104 | 0.0248 | 2.23 | 3.908 | 0.5277 | 3503.6 | 215851 | 13600000 | 881000000 | 0.3536 | 0.2676 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0071 | 0.0000 | 0.0426 | 0.0101 | 0.0922 | 0.0628 | 0.1525 | 0.0678 | 0.1489 | 0.0653 | 0.1915 | 0.0879 | 0.3617 | 0.7060 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0225 | 0.0100 | 0.0535 | 0.0627 | 0.0817 | 0.0677 | 0.0789 | 0.0652 | 0.1042 | 0.0677 | 0.6563 | 0.7268 | 0.0137 | 1.0000 | 0.0000 | 0.0000 | 0.0274 | 0.0000 | 0.0822 | 0.0000 | 0.0822 | 0.0000 | 0.1781 | 0.0000 | 0.1370 | 0.0000 | 0.2055 | 0.0000 | 0.2740 | 0.0000 | 0.0053 | 0.0053 | 0.0159 | 0.0265 | 0.0635 | 0.1111 | 0.1058 | 0.0899 | 0.5767 | 5 | 6 | 7 | 8 | 9 | 10 | 13 | 18 | 40 | 0.3348 | 9.79 | 2.064 | 0.7707 | 5081.6 | 2730000 | 1940000000 | 1570000000000 | 0.6341 | 0.0846 | 0.0349 | 0.0330 | 0.1163 | 0.0366 | 0.1453 | 0.0425 | 0.1628 | 0.0837 | 0.2006 | 0.1262 | 0.1919 | 0.1498 | 0.1163 | 0.1462 | 0.0233 | 0.1686 | 0.0087 | 0.2134 | 0.0053 | 0.0181 | 0.0079 | 0.0194 | 0.0184 | 0.0148 | 0.0202 | 0.0258 | 0.0746 | 0.0523 | 0.0886 | 0.0690 | 0.0912 | 0.0800 | 0.1202 | 0.1052 | 0.5737 | 0.6155 | 0.0025 | 0.0028 | 0.0013 | 0.0000 | 0.0088 | 0.0043 | 0.0251 | 0.0256 | 0.0842 | 0.0954 | 0.1256 | 0.1439 | 0.0942 | 0.1068 | 0.1344 | 0.1296 | 0.5239 | 0.4915 | 0.0022 | 0.0098 | 0.0065 | 0.0271 | 0.0869 | 0.0912 | 0.0988 | 0.1325 | 0.5451 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 84 | 350 | | 635 | 11961 | 63.2 | 10.04 | 161.70 | 197.63 | 50 | 54 | 57 | 61 | 63 | 66 | 68 | 71 | 76 | 0.0579 | 693 | 0.875 | 142.76 | 45.97 | 2 | 0.6299 | 400 | 0.0068 | 11.22 | 5.192 | 0.3174 | 4092.7 | 271580 | 18400000 | 1280000000 | 0.4246 | 0.2192 | 0.0020 | 0.0000 | 0.0061 | 0.0016 | 0.0242 | 0.0048 | 0.0364 | 0.0111 | 0.0667 | 0.0430 | 0.1091 | 0.0685 | 0.1172 | 0.0525 | 0.1960 | 0.0812 | 0.4424 | 0.7373 | 0.0018 | 0.0000 | 0.0053 | 0.0016 | 0.0124 | 0.0047 | 0.0284 | 0.0110 | 0.0443 | 0.0379 | 0.0585 | 0.0694 | 0.0709 | 0.0394 | 0.0816 | 0.0599 | 0.6968 | 0.7760 | 0.0580 | 0.3333 | 0.0870 | 0.0000 | 0.1594 | 0.3333 | 0.0725 | 0.3333 | 0.1739 | 0.0000 | 0.0870 | 0.0000 | 0.0580 | 0.0000 | 0.1014 | 0.0000 | 0.2029 | 0.0000 | 0.0060 | 0.0030 | 0.0328 | 0.0448 | 0.0836 | 0.1045 | 0.1104 | 0.1761 | 0.4388 | 14 | 18 | 22 | 31 | 58 | 116 | 205 | 315 | 458 | 0.0352 | 28.43 | 5.403 | 0.4619 | 65200.6 | 35400000 | 22500000000 | 16100000000000 | 0.5927 | 0.1032 | 0.1018 | 0.0034 | 0.2284 | 0.0353 | 0.3243 | 0.1826 | 0.1467 | 0.1894 | 0.1089 | 0.2031 | 0.0462 | 0.1570 | 0.0249 | 0.0990 | 0.0130 | 0.0728 | 0.0059 | 0.0575 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0020 | 0.0022 | 0.0142 | 0.0124 | 0.0583 | 0.0519 | 0.0965 | 0.0944 | 0.0720 | 0.0609 | 0.0991 | 0.0924 | 0.6569 | 0.6855 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0029 | 0.0060 | 0.0195 | 0.0279 | 0.0776 | 0.0835 | 0.1193 | 0.1370 | 0.0921 | 0.0943 | 0.1271 | 0.1346 | 0.5598 | 0.5161 | 0.0002 | 0.0002 | 0.0027 | 0.0176 | 0.0677 | 0.1015 | 0.0832 | 0.1135 | 0.6134 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1173 | 230 | | 893 | 1587 | 58.0 | 13.43 | 491.67 | 350.26 | 39 | 45 | 50 | 54 | 59 | 63 | 67 | 71 | 75 | 0.1878 | 298 | 1.216 | 22.85 | 8.25 | 1 | 0.0694 | 62 | 0.0063 | 5.77 | 5.275 | 0.3973 | 3548.7 | 226676 | 15000000 | 1020000000 | 0.4245 | 0.2042 | 0.0041 | 0.0000 | 0.0104 | 0.0000 | 0.0228 | 0.0012 | 0.0352 | 0.0119 | 0.1056 | 0.0380 | 0.1201 | 0.0403 | 0.1677 | 0.0712 | 0.1822 | 0.0830 | 0.3520 | 0.7544 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0058 | 0.0012 | 0.0159 | 0.0116 | 0.0418 | 0.0359 | 0.0390 | 0.0348 | 0.0592 | 0.0475 | 0.0649 | 0.0487 | 0.7706 | 0.8204 | 0.0095 | 0.0500 | 0.0143 | 0.1000 | 0.0190 | 0.0500 | 0.0476 | 0.2000 | 0.1381 | 0.3000 | 0.1095 | 0.1000 | 0.1810 | 0.0000 | 0.1905 | 0.2000 | 0.2905 | 0.0000 | 0.0043 | 0.0151 | 0.0151 | 0.0129 | 0.0430 | 0.0688 | 0.0860 | 0.1011 | 0.6538 | 107 | 162 | 233 | 315 | 418 | 517 | 636 | 803 | 998 | 0.0021 | 39.34 | 6.548 | 0.2363 | 364349.0 | 335000000 | 350000000000 | 398000000000000 | 0.5161 | 0.1411 | 0.0070 | 0.0000 | 0.0702 | 0.0035 | 0.1579 | 0.0228 | 0.2316 | 0.0683 | 0.2140 | 0.1278 | 0.1789 | 0.2277 | 0.0877 | 0.1611 | 0.0386 | 0.1664 | 0.0140 | 0.2224 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0061 | 0.0020 | 0.0255 | 0.0201 | 0.0522 | 0.0413 | 0.0765 | 0.0554 | 0.0667 | 0.0564 | 0.1129 | 0.0816 | 0.6590 | 0.7432 | 0.0019 | 0.0000 | 0.0000 | 0.0047 | 0.0111 | 0.0213 | 0.0390 | 0.0332 | 0.0686 | 0.0900 | 0.1317 | 0.1232 | 0.0891 | 0.0853 | 0.1132 | 0.1422 | 0.5455 | 0.5000 | 0.0000 | 0.0059 | 0.0089 | 0.0341 | 0.0548 | 0.0904 | 0.0919 | 0.1407 | 0.5733 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1178 | 149 | | 2587 | 12832 | 62.1 | 10.66 | 74.22 | 169.03 | 47 | 54 | 57 | 60 | 63 | 65 | 68 | 71 | 75 | 0.0646 | 829 | 0.944 | 80.06 | 19.03 | 2 | 0.0723 | 187 | 0.0369 | 1.29 | 3.638 | 0.6360 | 3969.1 | 260301 | 17500000 | 1200000000 | 0.4305 | 0.2137 | 0.0020 | 0.0000 | 0.0020 | 0.0004 | 0.0055 | 0.0008 | 0.0201 | 0.0075 | 0.0472 | 0.0210 | 0.0693 | 0.0334 | 0.0844 | 0.0346 | 0.1920 | 0.0516 | 0.5774 | 0.8507 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0018 | 0.0004 | 0.0079 | 0.0059 | 0.0238 | 0.0192 | 0.0331 | 0.0298 | 0.0348 | 0.0271 | 0.0591 | 0.0365 | 0.8386 | 0.8811 | 0.0719 | 0.0968 | 0.1079 | 0.1290 | 0.0755 | 0.1935 | 0.1151 | 0.0968 | 0.1043 | 0.1613 | 0.1187 | 0.1613 | 0.1475 | 0.0968 | 0.0827 | 0.0645 | 0.1763 | 0.0000 | 0.0036 | 0.0107 | 0.0220 | 0.0377 | 0.0519 | 0.0732 | 0.1087 | 0.1741 | 0.5181 | 15 | 19 | 23 | 28 | 32 | 38 | 43 | 50 | 94 | 0.1646 | 3.32 | 2.652 | 0.8090 | 34078.2 | 30400000 | 31700000000 | 35800000000000 | 0.6942 | 0.0754 | 0.1033 | 0.0274 | 0.0813 | 0.0364 | 0.0769 | 0.0502 | 0.0769 | 0.0707 | 0.1319 | 0.1021 | 0.1275 | 0.1360 | 0.1319 | 0.1585 | 0.1275 | 0.1667 | 0.1429 | 0.2520 | 0.0237 | 0.0180 | 0.0188 | 0.0239 | 0.0094 | 0.0319 | 0.0066 | 0.0430 | 0.0248 | 0.0663 | 0.0370 | 0.0857 | 0.0304 | 0.1021 | 0.0679 | 0.1201 | 0.7815 | 0.5089 | 0.0044 | 0.0017 | 0.0044 | 0.0035 | 0.0074 | 0.0095 | 0.0118 | 0.0173 | 0.0376 | 0.0528 | 0.0516 | 0.0692 | 0.0553 | 0.0614 | 0.1061 | 0.0882 | 0.7214 | 0.6964 | 0.0006 | 0.0038 | 0.0038 | 0.0101 | 0.0258 | 0.0396 | 0.0491 | 0.0931 | 0.7742 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 56 | 911 | | 384 | 7332 | 60.6 | 12.76 | 165.06 | 118.18 | 45 | 50 | 53 | 57 | 60 | 63 | 67 | 71 | 76 | 0.0614 | 450 | 0.519 | 130.54 | 26.91 | 0 | 1.0260 | 394 | 0.0099 | 9.19 | 4.826 | 0.3167 | 3828.9 | 252540 | 17400000 | 1250000000 | 0.4554 | 0.1729 | 0.0036 | 0.0000 | 0.0109 | 0.0028 | 0.0182 | 0.0055 | 0.0691 | 0.0194 | 0.1309 | 0.0720 | 0.1709 | 0.1219 | 0.1782 | 0.0914 | 0.2000 | 0.1607 | 0.2182 | 0.5263 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0093 | 0.0027 | 0.0247 | 0.0107 | 0.0957 | 0.0587 | 0.1235 | 0.1147 | 0.1173 | 0.0667 | 0.1420 | 0.1333 | 0.4877 | 0.6107 | 0.1020 | 0.0000 | 0.0612 | 0.1429 | 0.1224 | 0.0714 | 0.1020 | 0.3571 | 0.1633 | 0.2857 | 0.1837 | 0.0714 | 0.1633 | 0.0714 | 0.0612 | 0.0000 | 0.0408 | 0.0000 | 0.0053 | 0.0000 | 0.0106 | 0.0638 | 0.1596 | 0.1702 | 0.1596 | 0.1915 | 0.2394 | 18 | 37 | 71 | 117 | 158 | 195 | 232 | 274 | 329 | 0.0075 | 22.50 | 6.081 | 0.3343 | 41207.1 | 12200000 | 3970000000 | 1400000000000 | 0.4642 | 0.1955 | 0.0148 | 0.0016 | 0.1134 | 0.0089 | 0.1997 | 0.0335 | 0.1935 | 0.0895 | 0.1671 | 0.1734 | 0.1507 | 0.1952 | 0.0870 | 0.1593 | 0.0583 | 0.1613 | 0.0155 | 0.1774 | 0.0000 | 0.0000 | 0.0005 | 0.0013 | 0.0024 | 0.0011 | 0.0128 | 0.0077 | 0.0443 | 0.0302 | 0.0775 | 0.0562 | 0.0828 | 0.0523 | 0.1239 | 0.0826 | 0.6558 | 0.7687 | 0.0003 | 0.0023 | 0.0052 | 0.0099 | 0.0108 | 0.0185 | 0.0241 | 0.0468 | 0.0927 | 0.1342 | 0.1524 | 0.1640 | 0.1405 | 0.1486 | 0.1552 | 0.1721 | 0.4188 | 0.3036 | 0.0011 | 0.0025 | 0.0040 | 0.0178 | 0.0627 | 0.1136 | 0.1110 | 0.1627 | 0.5246 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 992 | 554 | | 458 | 453 | 58.6 | 18.24 | 15.98 | 3.18 | 38 | 42 | 46 | 52 | 56 | 61 | 66 | 72 | 84 | 0.4040 | 183 | 0.735 | 110.07 | 27.07 | 1 | 0.6135 | 281 | 0.0119 | 5.25 | 4.713 | 0.4351 | 3769.0 | 265175 | 20300000 | 1680000000 | 0.3546 | 0.2594 | 0.0000 | 0.0000 | 0.0199 | 0.0000 | 0.0448 | 0.0000 | 0.0597 | 0.0052 | 0.1294 | 0.0735 | 0.2139 | 0.1417 | 0.1791 | 0.0761 | 0.1343 | 0.1155 | 0.2189 | 0.5879 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0164 | 0.0046 | 0.0656 | 0.0371 | 0.1049 | 0.0928 | 0.0721 | 0.0278 | 0.0951 | 0.0603 | 0.6459 | 0.7773 | 0.0096 | 0.0000 | 0.0000 | 0.0000 | 0.0096 | 0.0600 | 0.0673 | 0.1800 | 0.2019 | 0.1000 | 0.1731 | 0.2800 | 0.0865 | 0.1400 | 0.1635 | 0.0600 | 0.2885 | 0.1800 | 0.0000 | 0.0000 | 0.0048 | 0.0335 | 0.1435 | 0.1483 | 0.1100 | 0.1627 | 0.3971 | 12 | 13 | 14 | 15 | 16 | 17 | 17 | 18 | 20 | 0.8738 | 0.06 | 0.306 | 0.9702 | 265.5 | 4574.87 | 81636.7 | 1510000 | 0.5349 | 0.1049 | 0.0031 | 0.0000 | 0.0217 | 0.0000 | 0.0683 | 0.0046 | 0.1211 | 0.0207 | 0.2050 | 0.1359 | 0.1739 | 0.1544 | 0.1739 | 0.1613 | 0.1801 | 0.1521 | 0.0528 | 0.3710 | 0.0026 | 0.0000 | 0.0078 | 0.0000 | 0.0284 | 0.0045 | 0.0413 | 0.0089 | 0.1835 | 0.1250 | 0.1550 | 0.1473 | 0.1576 | 0.1518 | 0.1938 | 0.1384 | 0.2300 | 0.4241 | 0.2923 | 0.5000 | 0.1846 | 0.2143 | 0.1385 | 0.2143 | 0.1846 | 0.0714 | 0.1077 | 0.0000 | 0.0615 | 0.0000 | 0.0308 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0586 | 0.1328 | 0.1445 | 0.1758 | 0.1680 | 0.1367 | 0.1055 | 0.0586 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1218 | 913 | | 1758 | 2499 | 60.5 | 14.09 | 168.06 | 202.27 | 37 | 49 | 56 | 60 | 64 | 66 | 69 | 72 | 76 | 0.1709 | 427 | 1.246 | 80.75 | 28.65 | 1 | 0.1115 | 196 | 0.0648 | 0.70 | 3.033 | 0.7245 | 3855.7 | 255103 | 17300000 | 1200000000 | 0.4086 | 0.2272 | 0.0020 | 0.0000 | 0.0127 | 0.0000 | 0.0402 | 0.0057 | 0.0412 | 0.0076 | 0.0794 | 0.0264 | 0.1039 | 0.0415 | 0.1265 | 0.0447 | 0.1657 | 0.0730 | 0.4284 | 0.8011 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0035 | 0.0056 | 0.0064 | 0.0062 | 0.0275 | 0.0249 | 0.0346 | 0.0386 | 0.0388 | 0.0311 | 0.0473 | 0.0398 | 0.8397 | 0.8538 | 0.0101 | 0.3889 | 0.0455 | 0.1667 | 0.0758 | 0.3889 | 0.0934 | 0.0556 | 0.1641 | 0.0000 | 0.1919 | 0.0000 | 0.1490 | 0.0000 | 0.1086 | 0.0000 | 0.1616 | 0.0000 | 0.0000 | 0.0036 | 0.0073 | 0.0255 | 0.0473 | 0.0673 | 0.1092 | 0.1583 | 0.5814 | 4 | 6 | 7 | 11 | 74 | 155 | 243 | 343 | 479 | 0.0246 | 19.24 | 4.564 | 0.3199 | 69139.4 | 35300000 | 20400000000 | 12900000000000 | 0.3902 | 0.2388 | 0.0270 | 0.0023 | 0.0991 | 0.0070 | 0.2748 | 0.0651 | 0.1802 | 0.1256 | 0.1036 | 0.1419 | 0.0856 | 0.2186 | 0.0901 | 0.1256 | 0.0676 | 0.0814 | 0.0721 | 0.2326 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0025 | 0.0102 | 0.0076 | 0.0361 | 0.0352 | 0.0981 | 0.0730 | 0.0796 | 0.0554 | 0.0907 | 0.0671 | 0.6824 | 0.7592 | 0.0000 | 0.0013 | 0.0000 | 0.0039 | 0.0012 | 0.0066 | 0.0210 | 0.0197 | 0.0723 | 0.0748 | 0.1142 | 0.1391 | 0.1037 | 0.1063 | 0.1224 | 0.1299 | 0.5653 | 0.5184 | 0.0000 | 0.0031 | 0.0031 | 0.0084 | 0.0670 | 0.0974 | 0.0827 | 0.1068 | 0.6314 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1160 | 141 | | 3233 | 11358 | 59.9 | 15.14 | 124.51 | 201.52 | 40 | 47 | 52 | 56 | 59 | 63 | 68 | 73 | 80 | 0.0812 | 922 | 1.116 | 66.27 | 24.02 | 8 | 0.0520 | 168 | 0.0039 | 9.71 | 5.841 | 0.3283 | 3816.7 | 256199 | 18000000 | 1310000000 | 0.4210 | 0.2075 | 0.0016 | 0.0007 | 0.0121 | 0.0007 | 0.0236 | 0.0021 | 0.0356 | 0.0084 | 0.0773 | 0.0453 | 0.1135 | 0.0541 | 0.1321 | 0.0699 | 0.1908 | 0.1173 | 0.4134 | 0.7015 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0058 | 0.0007 | 0.0136 | 0.0046 | 0.0342 | 0.0320 | 0.0427 | 0.0346 | 0.0497 | 0.0369 | 0.0730 | 0.0515 | 0.7767 | 0.8398 | 0.0133 | 0.0415 | 0.0146 | 0.0553 | 0.0320 | 0.0968 | 0.0626 | 0.0829 | 0.0786 | 0.1613 | 0.1012 | 0.1705 | 0.1318 | 0.1475 | 0.1491 | 0.1521 | 0.4168 | 0.0922 | 0.0063 | 0.0101 | 0.0184 | 0.0380 | 0.0582 | 0.0671 | 0.0880 | 0.1063 | 0.6076 | 16 | 20 | 23 | 28 | 42 | 71 | 118 | 184 | 325 | 0.0815 | 10.02 | 4.228 | 0.6192 | 56109.0 | 50800000 | 64300000000 | 94700000000000 | 0.6731 | 0.0824 | 0.0382 | 0.0025 | 0.1393 | 0.0177 | 0.1670 | 0.0809 | 0.1460 | 0.1089 | 0.1651 | 0.1648 | 0.1431 | 0.1712 | 0.1002 | 0.1344 | 0.0716 | 0.1363 | 0.0296 | 0.1834 | 0.0000 | 0.0004 | 0.0018 | 0.0020 | 0.0063 | 0.0029 | 0.0266 | 0.0186 | 0.0673 | 0.0669 | 0.0986 | 0.0822 | 0.0819 | 0.0716 | 0.1122 | 0.1042 | 0.6054 | 0.6512 | 0.0004 | 0.0029 | 0.0043 | 0.0062 | 0.0093 | 0.0083 | 0.0377 | 0.0360 | 0.0890 | 0.0989 | 0.1328 | 0.1320 | 0.0800 | 0.0757 | 0.1120 | 0.1105 | 0.5345 | 0.5294 | 0.0012 | 0.0027 | 0.0067 | 0.0307 | 0.0828 | 0.1186 | 0.0791 | 0.1205 | 0.5577 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 779 | 772 | | 630 | 2293 | 62.2 | 11.79 | 6.82 | 2.35 | 48 | 51 | 54 | 57 | 61 | 65 | 69 | 73 | 77 | 0.1522 | 349 | 0.662 | 34.06 | 7.21 | 2 | 0.1444 | 91 | 0.0668 | 0.76 | 2.979 | 0.7113 | 4008.3 | 267309 | 18400000 | 1310000000 | 0.4337 | 0.1967 | 0.0000 | 0.0000 | 0.0115 | 0.0000 | 0.0253 | 0.0016 | 0.0484 | 0.0081 | 0.1106 | 0.0520 | 0.1521 | 0.0846 | 0.1728 | 0.0618 | 0.2166 | 0.1317 | 0.2627 | 0.6602 | 0.0000 | 0.0000 | 0.0038 | 0.0000 | 0.0075 | 0.0016 | 0.0226 | 0.0048 | 0.0658 | 0.0476 | 0.0921 | 0.0778 | 0.0714 | 0.0429 | 0.1372 | 0.0984 | 0.5996 | 0.7270 | 0.0102 | 0.1333 | 0.0408 | 0.0000 | 0.0612 | 0.1333 | 0.1633 | 0.4000 | 0.1837 | 0.0000 | 0.2245 | 0.2667 | 0.1224 | 0.0000 | 0.1020 | 0.0000 | 0.0918 | 0.0667 | 0.0000 | 0.0000 | 0.0065 | 0.0647 | 0.0971 | 0.1100 | 0.1197 | 0.1553 | 0.4466 | 4 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 10 | 0.0239 | 6.69 | 4.216 | 0.3943 | 52.0 | 441.077 | 4128.92 | 42300.9 | 0.5603 | 0.1272 | 0.0098 | 0.0035 | 0.0446 | 0.0081 | 0.1223 | 0.0190 | 0.1982 | 0.0432 | 0.2580 | 0.0876 | 0.1839 | 0.1643 | 0.1205 | 0.2190 | 0.0509 | 0.2824 | 0.0116 | 0.1729 | 0.0044 | 0.0000 | 0.0196 | 0.0010 | 0.0418 | 0.0068 | 0.0982 | 0.0209 | 0.1483 | 0.0507 | 0.1781 | 0.0989 | 0.1749 | 0.1495 | 0.1477 | 0.2567 | 0.1869 | 0.4155 | 0.1638 | 0.1855 | 0.1048 | 0.0943 | 0.1114 | 0.1006 | 0.1048 | 0.1132 | 0.1201 | 0.1226 | 0.1004 | 0.1164 | 0.1048 | 0.1069 | 0.0873 | 0.0943 | 0.1026 | 0.0660 | 0.0254 | 0.0806 | 0.1569 | 0.1490 | 0.1350 | 0.1060 | 0.1060 | 0.0947 | 0.1464 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 159 | 548 | | 379 | 3429 | 61.1 | 11.87 | 9.11 | 3.08 | 46 | 49 | 53 | 56 | 61 | 64 | 69 | 74 | 78 | 0.1105 | 379 | 1.104 | 39.12 | 14.21 | 3 | 0.2797 | 106 | 0.0614 | 0.78 | 2.978 | 0.7032 | 3871.4 | 253941 | 17200000 | 1190000000 | 0.4114 | 0.2187 | 0.0000 | 0.0000 | 0.0338 | 0.0000 | 0.0211 | 0.0027 | 0.0717 | 0.0133 | 0.1392 | 0.0398 | 0.1477 | 0.0928 | 0.1477 | 0.0398 | 0.1181 | 0.0955 | 0.3207 | 0.7162 | 0.0000 | 0.0000 | 0.0223 | 0.0000 | 0.0096 | 0.0026 | 0.0287 | 0.0132 | 0.0510 | 0.0396 | 0.0701 | 0.0923 | 0.0605 | 0.0343 | 0.0764 | 0.0686 | 0.6815 | 0.7493 | 0.0000 | 0.0000 | 0.0000 | 1.0000 | 0.0519 | 0.0000 | 0.0649 | 0.0000 | 0.2208 | 0.0000 | 0.1818 | 0.0000 | 0.2078 | 0.0000 | 0.1688 | 0.0000 | 0.1039 | 0.0000 | 0.0000 | 0.0209 | 0.0105 | 0.0419 | 0.0995 | 0.0942 | 0.1047 | 0.1152 | 0.5131 | 5 | 7 | 7 | 8 | 9 | 10 | 10 | 11 | 13 | 0.0137 | 13.19 | 4.745 | 0.3048 | 92.4 | 1038.16 | 12866.9 | 175722 | 0.4767 | 0.1774 | 0.0306 | 0.0011 | 0.0977 | 0.0053 | 0.1939 | 0.0174 | 0.2558 | 0.0474 | 0.2165 | 0.0913 | 0.1348 | 0.1588 | 0.0547 | 0.2421 | 0.0160 | 0.2736 | 0.0000 | 0.1629 | 0.0040 | 0.0000 | 0.0215 | 0.0007 | 0.0553 | 0.0059 | 0.0975 | 0.0180 | 0.1615 | 0.0475 | 0.1708 | 0.0992 | 0.1550 | 0.1490 | 0.1519 | 0.2449 | 0.1826 | 0.4348 | 0.1258 | 0.1928 | 0.1479 | 0.1639 | 0.1336 | 0.1470 | 0.1291 | 0.1012 | 0.1049 | 0.1036 | 0.0894 | 0.1108 | 0.0993 | 0.0916 | 0.1038 | 0.0675 | 0.0662 | 0.0217 | 0.0221 | 0.0550 | 0.1024 | 0.1185 | 0.1422 | 0.1212 | 0.1315 | 0.1245 | 0.1827 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 525 | 784 | | 306 | 3162 | 64.0 | 11.66 | 117.65 | 178.73 | 49 | 52 | 58 | 61 | 64 | 67 | 70 | 74 | 79 | 0.1395 | 441 | 1.153 | 68.73 | 23.77 | 1 | 0.5556 | 170 | 0.0077 | 10.17 | 5.047 | 0.3110 | 4226.0 | 287862 | 20200000 | 1450000000 | 0.4562 | 0.1761 | 0.0000 | 0.0000 | 0.0147 | 0.0033 | 0.0196 | 0.0000 | 0.0686 | 0.0133 | 0.1520 | 0.0365 | 0.1765 | 0.1794 | 0.1520 | 0.0332 | 0.1912 | 0.1296 | 0.2255 | 0.6047 | 0.0000 | 0.0000 | 0.0118 | 0.0033 | 0.0039 | 0.0000 | 0.0433 | 0.0131 | 0.0630 | 0.0359 | 0.1299 | 0.1634 | 0.0591 | 0.0327 | 0.1378 | 0.0882 | 0.5512 | 0.6634 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0800 | 0.0000 | 0.0600 | 0.8000 | 0.2200 | 0.2000 | 0.2000 | 0.0000 | 0.1400 | 0.0000 | 0.1400 | 0.0000 | 0.1200 | 0.0000 | 0.0062 | 0.0124 | 0.0248 | 0.0559 | 0.1242 | 0.0994 | 0.1242 | 0.1180 | 0.4348 | 11 | 12 | 13 | 15 | 18 | 44 | 106 | 220 | 400 | 0.1851 | 37.34 | 4.002 | 0.6018 | 45776.0 | 25200000 | 16900000000 | 13200000000000 | 0.6720 | 0.0567 | 0.1282 | 0.0081 | 0.1949 | 0.0782 | 0.2513 | 0.1240 | 0.1179 | 0.1563 | 0.1128 | 0.1725 | 0.0667 | 0.1590 | 0.0359 | 0.0755 | 0.0359 | 0.0916 | 0.0564 | 0.1348 | 0.0010 | 0.0000 | 0.0010 | 0.0009 | 0.0040 | 0.0027 | 0.0210 | 0.0153 | 0.0791 | 0.0694 | 0.1351 | 0.1127 | 0.1011 | 0.0902 | 0.1592 | 0.1461 | 0.4985 | 0.5627 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0012 | 0.0054 | 0.0348 | 0.0312 | 0.1057 | 0.1098 | 0.1480 | 0.1707 | 0.1294 | 0.1328 | 0.1654 | 0.1667 | 0.4142 | 0.3821 | 0.0011 | 0.0000 | 0.0033 | 0.0255 | 0.0909 | 0.1408 | 0.1098 | 0.1663 | 0.4623 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1243 | 854 | | 722 | 7966 | 63.7 | 17.26 | 99.18 | 192.37 | 47 | 51 | 53 | 56 | 60 | 63 | 68 | 74 | 85 | 0.0734 | 585 | 0.421 | 183.11 | 37.80 | 0 | 0.8726 | 630 | 0.0093 | 10.56 | 5.018 | 0.3434 | 4360.7 | 324711 | 26600000 | 2420000000 | 0.4665 | 0.1732 | 0.0048 | 0.0000 | 0.0238 | 0.0000 | 0.0499 | 0.0060 | 0.0950 | 0.0255 | 0.1354 | 0.0510 | 0.1853 | 0.0990 | 0.1663 | 0.1049 | 0.1663 | 0.1094 | 0.1734 | 0.6042 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0128 | 0.0028 | 0.0475 | 0.0097 | 0.0786 | 0.0444 | 0.1408 | 0.0819 | 0.1261 | 0.0611 | 0.1481 | 0.0833 | 0.4388 | 0.7167 | 0.0000 | 0.0000 | 0.0317 | 0.0377 | 0.0159 | 0.0755 | 0.0952 | 0.0755 | 0.1825 | 0.3019 | 0.1825 | 0.1321 | 0.1508 | 0.0566 | 0.1508 | 0.2075 | 0.1905 | 0.1132 | 0.0036 | 0.0180 | 0.0288 | 0.0791 | 0.1259 | 0.1691 | 0.1295 | 0.1511 | 0.2950 | 10 | 12 | 14 | 15 | 17 | 19 | 31 | 113 | 371 | 0.1151 | 73.14 | 4.084 | 0.5429 | 46837.2 | 32700000 | 27500000000 | 26300000000000 | 0.6007 | 0.1115 | 0.2664 | 0.0211 | 0.4953 | 0.1607 | 0.2103 | 0.5011 | 0.0280 | 0.1882 | 0.0000 | 0.0782 | 0.0000 | 0.0338 | 0.0000 | 0.0127 | 0.0000 | 0.0042 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0022 | 0.0015 | 0.0056 | 0.0036 | 0.0185 | 0.0247 | 0.0888 | 0.0781 | 0.1355 | 0.1183 | 0.0748 | 0.0848 | 0.1231 | 0.1177 | 0.5509 | 0.5707 | 0.0006 | 0.0007 | 0.0013 | 0.0041 | 0.0083 | 0.0082 | 0.0230 | 0.0211 | 0.0856 | 0.0958 | 0.1540 | 0.1501 | 0.0818 | 0.0795 | 0.1176 | 0.1291 | 0.5278 | 0.5115 | 0.0012 | 0.0024 | 0.0054 | 0.0198 | 0.0929 | 0.1360 | 0.0827 | 0.1210 | 0.5386 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 462 | 109 | | 459 | 1169 | 64.3 | 13.23 | 8.02 | 2.47 | 48 | 52 | 57 | 61 | 64 | 67 | 71 | 74 | 79 | 0.2515 | 294 | 0.892 | 64.33 | 20.81 | 1 | 0.3791 | 174 | 0.0526 | 1.06 | 3.212 | 0.6390 | 4308.5 | 301320 | 22000000 | 1690000000 | 0.4020 | 0.2263 | 0.0000 | 0.0000 | 0.0063 | 0.0023 | 0.0094 | 0.0068 | 0.0408 | 0.0068 | 0.0940 | 0.0502 | 0.1160 | 0.1073 | 0.1473 | 0.0662 | 0.2508 | 0.0936 | 0.3354 | 0.6667 | 0.0000 | 0.0000 | 0.0026 | 0.0022 | 0.0026 | 0.0066 | 0.0238 | 0.0044 | 0.0556 | 0.0462 | 0.0635 | 0.0879 | 0.0714 | 0.0505 | 0.1111 | 0.0725 | 0.6693 | 0.7297 | 0.0678 | 0.0000 | 0.0508 | 0.0000 | 0.1356 | 0.0588 | 0.0339 | 0.1176 | 0.2034 | 0.2941 | 0.1186 | 0.1176 | 0.0678 | 0.1176 | 0.1356 | 0.2353 | 0.1864 | 0.0588 | 0.0041 | 0.0041 | 0.0245 | 0.0245 | 0.0735 | 0.0939 | 0.0898 | 0.1796 | 0.5061 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0200 | 12.70 | 4.330 | 0.3019 | 70.5 | 664.57 | 6651.59 | 70129.1 | 0.5248 | 0.1240 | 0.0136 | 0.0000 | 0.0492 | 0.0010 | 0.1121 | 0.0149 | 0.2462 | 0.0378 | 0.2394 | 0.0746 | 0.2190 | 0.1303 | 0.1002 | 0.2139 | 0.0187 | 0.2806 | 0.0017 | 0.2468 | 0.0000 | 0.0000 | 0.0099 | 0.0009 | 0.0221 | 0.0027 | 0.0585 | 0.0220 | 0.1170 | 0.0577 | 0.2064 | 0.0843 | 0.2274 | 0.1357 | 0.2506 | 0.2878 | 0.1082 | 0.4088 | 0.1199 | 0.5814 | 0.2461 | 0.2907 | 0.2366 | 0.0814 | 0.1924 | 0.0349 | 0.1293 | 0.0116 | 0.0536 | 0.0000 | 0.0158 | 0.0000 | 0.0032 | 0.0000 | 0.0032 | 0.0000 | 0.0126 | 0.0535 | 0.1258 | 0.2013 | 0.2186 | 0.1714 | 0.1336 | 0.0708 | 0.0126 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1246 | 581 | | 5724 | 10893 | 64.5 | 15.39 | 236.73 | 211.09 | 47 | 52 | 56 | 60 | 63 | 66 | 70 | 75 | 83 | 0.1007 | 1097 | 0.634 | 184.57 | 34.06 | 2 | 0.0786 | 450 | 0.0087 | 5.31 | 5.104 | 0.4181 | 4403.3 | 318930 | 24700000 | 2070000000 | 0.5293 | 0.1575 | 0.0011 | 0.0000 | 0.0029 | 0.0002 | 0.0149 | 0.0025 | 0.0344 | 0.0079 | 0.0831 | 0.0249 | 0.1403 | 0.0624 | 0.1470 | 0.0543 | 0.2027 | 0.0933 | 0.3736 | 0.7545 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0073 | 0.0014 | 0.0168 | 0.0048 | 0.0432 | 0.0173 | 0.0852 | 0.0464 | 0.0787 | 0.0324 | 0.1224 | 0.0582 | 0.6454 | 0.8396 | 0.0146 | 0.0251 | 0.0258 | 0.0282 | 0.0538 | 0.0219 | 0.0806 | 0.1066 | 0.1333 | 0.1818 | 0.1445 | 0.1630 | 0.1333 | 0.1348 | 0.1344 | 0.1285 | 0.2800 | 0.2100 | 0.0049 | 0.0125 | 0.0245 | 0.0623 | 0.1061 | 0.1303 | 0.1318 | 0.1477 | 0.3799 | 16 | 25 | 64 | 130 | 196 | 261 | 329 | 412 | 529 | 0.0116 | 86.41 | 6.934 | 0.2713 | 100595.0 | 54000000 | 33700000000 | 23600000000000 | 0.4576 | 0.1893 | 0.0320 | 0.0013 | 0.1436 | 0.0119 | 0.2339 | 0.0569 | 0.1831 | 0.1264 | 0.1737 | 0.1747 | 0.1260 | 0.2062 | 0.0652 | 0.1467 | 0.0332 | 0.1364 | 0.0094 | 0.1396 | 0.0005 | 0.0003 | 0.0027 | 0.0008 | 0.0034 | 0.0019 | 0.0151 | 0.0095 | 0.0589 | 0.0467 | 0.0943 | 0.0811 | 0.0861 | 0.0713 | 0.1289 | 0.1061 | 0.6100 | 0.6824 | 0.0003 | 0.0012 | 0.0025 | 0.0031 | 0.0076 | 0.0127 | 0.0227 | 0.0347 | 0.0882 | 0.1018 | 0.1372 | 0.1535 | 0.1175 | 0.1148 | 0.1447 | 0.1528 | 0.4794 | 0.4254 | 0.0017 | 0.0015 | 0.0040 | 0.0185 | 0.0733 | 0.1092 | 0.0968 | 0.1432 | 0.5521 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 838 | 827 | | 348 | 3785 | 69.6 | 9.59 | 7.19 | 2.56 | 58 | 61 | 63 | 66 | 69 | 71 | 74 | 78 | 83 | 0.1007 | 381 | 1.208 | 26.48 | 9.85 | 4 | 0.2011 | 70 | 0.0757 | 0.82 | 2.819 | 0.6940 | 4931.9 | 356260 | 26200000 | 1970000000 | 0.3634 | 0.2597 | 0.0033 | 0.0000 | 0.0100 | 0.0000 | 0.0133 | 0.0029 | 0.0332 | 0.0144 | 0.0698 | 0.0720 | 0.0997 | 0.0778 | 0.1096 | 0.0692 | 0.2359 | 0.1268 | 0.4252 | 0.6369 | 0.0030 | 0.0000 | 0.0000 | 0.0000 | 0.0090 | 0.0029 | 0.0181 | 0.0144 | 0.0633 | 0.0690 | 0.0843 | 0.0776 | 0.0663 | 0.0690 | 0.1506 | 0.1149 | 0.6054 | 0.6523 | 0.0323 | 1.0000 | 0.0000 | 0.0000 | 0.1613 | 0.0000 | 0.2258 | 0.0000 | 0.1613 | 0.0000 | 0.0968 | 0.0000 | 0.1935 | 0.0000 | 0.1290 | 0.0000 | 0.0000 | 0.0000 | 0.0123 | 0.0062 | 0.0247 | 0.0988 | 0.1358 | 0.1420 | 0.1235 | 0.1728 | 0.2840 | 4 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 0.0188 | 7.92 | 4.396 | 0.3583 | 58.2 | 526.12 | 5258.33 | 57582.2 | 0.4841 | 0.1761 | 0.0222 | 0.0039 | 0.0672 | 0.0054 | 0.1627 | 0.0219 | 0.2267 | 0.0409 | 0.2391 | 0.0828 | 0.1725 | 0.1441 | 0.0826 | 0.2539 | 0.0246 | 0.3015 | 0.0025 | 0.1456 | 0.0046 | 0.0003 | 0.0185 | 0.0006 | 0.0490 | 0.0059 | 0.0817 | 0.0178 | 0.1214 | 0.0422 | 0.1762 | 0.0716 | 0.1689 | 0.1446 | 0.1823 | 0.2904 | 0.1974 | 0.4267 | 0.1226 | 0.1623 | 0.1493 | 0.1451 | 0.1143 | 0.1019 | 0.1184 | 0.1036 | 0.0917 | 0.0829 | 0.0937 | 0.0760 | 0.0814 | 0.0864 | 0.0937 | 0.1330 | 0.1349 | 0.1088 | 0.0153 | 0.0463 | 0.0769 | 0.1084 | 0.1441 | 0.1724 | 0.1585 | 0.1298 | 0.1483 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1017 | 554 | | 378 | 9755 | 70.8 | 9.18 | 6.27 | 2.35 | 58 | 62 | 65 | 69 | 72 | 74 | 76 | 79 | 82 | 0.0685 | 668 | 1.025 | 80.23 | 26.63 | 2 | 0.5556 | 210 | 0.0307 | 2.20 | 3.799 | 0.5317 | 5100.6 | 373029 | 27700000 | 2080000000 | 0.3766 | 0.2528 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0000 | 0.0121 | 0.0053 | 0.0725 | 0.0556 | 0.0816 | 0.0635 | 0.0816 | 0.0503 | 0.1178 | 0.0688 | 0.6284 | 0.7566 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0000 | 0.0116 | 0.0053 | 0.0607 | 0.0556 | 0.0665 | 0.0635 | 0.0520 | 0.0503 | 0.0838 | 0.0688 | 0.7197 | 0.7566 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0667 | 0.0000 | 0.2667 | 0.0000 | 0.0000 | 0.0000 | 0.2667 | 0.0000 | 0.2000 | 0.0000 | 0.0000 | 0.0000 | 0.1333 | 0.0000 | 0.0000 | 0.0093 | 0.0139 | 0.0324 | 0.0694 | 0.0787 | 0.0972 | 0.1481 | 0.5509 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.2315 | 0.45 | 1.048 | 0.5873 | 44.8 | 356.698 | 3133.82 | 30121.9 | 0.5230 | 0.1563 | 0.0095 | 0.0016 | 0.0423 | 0.0054 | 0.1159 | 0.0156 | 0.1913 | 0.0399 | 0.2491 | 0.0756 | 0.2068 | 0.1496 | 0.1260 | 0.2580 | 0.0507 | 0.3008 | 0.0085 | 0.1535 | 0.0009 | 0.0000 | 0.0033 | 0.0003 | 0.0157 | 0.0022 | 0.0417 | 0.0102 | 0.0896 | 0.0267 | 0.1561 | 0.0434 | 0.2071 | 0.1072 | 0.2316 | 0.2692 | 0.2540 | 0.5409 | 0.0990 | 0.1881 | 0.1831 | 0.2085 | 0.1795 | 0.1599 | 0.1502 | 0.1178 | 0.1272 | 0.0944 | 0.0980 | 0.0655 | 0.0618 | 0.0505 | 0.0512 | 0.0589 | 0.0501 | 0.0565 | 0.0080 | 0.0313 | 0.0735 | 0.1349 | 0.1725 | 0.1695 | 0.1459 | 0.1396 | 0.1248 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 279 | 429 | | 995 | 12586 | 70.7 | 14.90 | 155.58 | 186.93 | 55 | 59 | 63 | 66 | 69 | 72 | 76 | 81 | 90 | 0.0678 | 853 | 0.399 | 137.53 | 31.00 | 1 | 0.5668 | 564 | 0.0090 | 7.28 | 5.031 | 0.3913 | 5218.8 | 403150 | 32700000 | 2780000000 | 0.5290 | 0.1303 | 0.0014 | 0.0000 | 0.0041 | 0.0000 | 0.0218 | 0.0032 | 0.0476 | 0.0139 | 0.1252 | 0.0586 | 0.1823 | 0.1471 | 0.1469 | 0.0768 | 0.1524 | 0.1333 | 0.3184 | 0.5672 | 0.0012 | 0.0000 | 0.0012 | 0.0000 | 0.0046 | 0.0020 | 0.0207 | 0.0061 | 0.0794 | 0.0499 | 0.1427 | 0.1314 | 0.0863 | 0.0540 | 0.1116 | 0.0967 | 0.5524 | 0.6599 | 0.0149 | 0.0455 | 0.0149 | 0.0000 | 0.0522 | 0.1136 | 0.1343 | 0.1136 | 0.2015 | 0.2955 | 0.2015 | 0.2045 | 0.1119 | 0.0227 | 0.1269 | 0.1818 | 0.1418 | 0.0227 | 0.0068 | 0.0158 | 0.0158 | 0.0813 | 0.1512 | 0.1558 | 0.1129 | 0.1490 | 0.3115 | 16 | 20 | 30 | 53 | 84 | 116 | 167 | 264 | 418 | 0.0235 | 46.09 | 5.759 | 0.4355 | 59144.7 | 33000000 | 22700000000 | 17700000000000 | 0.5490 | 0.1235 | 0.0353 | 0.0025 | 0.1470 | 0.0151 | 0.2292 | 0.0792 | 0.1425 | 0.1235 | 0.1447 | 0.1704 | 0.1190 | 0.1746 | 0.0816 | 0.1179 | 0.0654 | 0.1193 | 0.0353 | 0.1975 | 0.0004 | 0.0007 | 0.0004 | 0.0019 | 0.0042 | 0.0029 | 0.0129 | 0.0102 | 0.0601 | 0.0507 | 0.1106 | 0.0865 | 0.0811 | 0.0676 | 0.1162 | 0.1025 | 0.6141 | 0.6771 | 0.0009 | 0.0010 | 0.0023 | 0.0017 | 0.0032 | 0.0023 | 0.0227 | 0.0252 | 0.0827 | 0.1026 | 0.1474 | 0.1437 | 0.0903 | 0.1010 | 0.1282 | 0.1400 | 0.5223 | 0.4826 | 0.0002 | 0.0015 | 0.0037 | 0.0187 | 0.0791 | 0.1231 | 0.0843 | 0.1271 | 0.5622 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 125 | 887 | | 914 | 10249 | 57.4 | 40.69 | 232.85 | 304.99 | 28 | 31 | 33 | 35 | 38 | 42 | 56 | 82 | 127 | 0.0631 | 647 | 1.229 | 27.66 | 9.43 | 1 | 0.0722 | 66 | 0.0076 | 22.99 | 5.445 | 0.3165 | 4951.9 | 588247 | 83100000 | 12800000000 | 0.3258 | 0.3035 | 0.0088 | 0.0152 | 0.0000 | 0.0127 | 0.0531 | 0.0482 | 0.1239 | 0.0736 | 0.3451 | 0.1624 | 0.2832 | 0.1574 | 0.1416 | 0.1650 | 0.0354 | 0.1421 | 0.0088 | 0.2234 | 0.0000 | 0.0103 | 0.0000 | 0.0086 | 0.0091 | 0.0325 | 0.0151 | 0.0462 | 0.0393 | 0.0856 | 0.0665 | 0.0805 | 0.0665 | 0.0702 | 0.0634 | 0.0771 | 0.7402 | 0.5890 | 0.0000 | 0.0053 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0046 | 0.0211 | 0.0826 | 0.0842 | 0.0872 | 0.0579 | 0.0459 | 0.0737 | 0.1101 | 0.0895 | 0.6697 | 0.6684 | 0.0000 | 0.0000 | 0.0037 | 0.0297 | 0.0409 | 0.0632 | 0.0743 | 0.0706 | 0.7175 | 22 | 26 | 32 | 50 | 83 | 141 | 256 | 424 | 686 | 0.0356 | 29.95 | 5.321 | 0.4926 | 147227.0 | 131000000 | 137000000000 | 161000000000000 | 0.6516 | 0.0660 | 0.0697 | 0.0026 | 0.1780 | 0.0222 | 0.2107 | 0.0941 | 0.1395 | 0.1359 | 0.1543 | 0.1737 | 0.1157 | 0.1966 | 0.0772 | 0.1261 | 0.0356 | 0.1261 | 0.0193 | 0.1228 | 0.0008 | 0.0002 | 0.0011 | 0.0012 | 0.0025 | 0.0051 | 0.0195 | 0.0177 | 0.0641 | 0.0572 | 0.0786 | 0.0824 | 0.0675 | 0.0545 | 0.0853 | 0.0863 | 0.6804 | 0.6953 | 0.0010 | 0.0015 | 0.0031 | 0.0035 | 0.0062 | 0.0073 | 0.0244 | 0.0289 | 0.0714 | 0.0763 | 0.0975 | 0.0960 | 0.0752 | 0.0867 | 0.0962 | 0.1044 | 0.6250 | 0.5954 | 0.0006 | 0.0012 | 0.0046 | 0.0178 | 0.0705 | 0.0911 | 0.0644 | 0.0929 | 0.6569 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 818 | 411 | | 1111 | 7364 | 67.7 | 19.08 | 51.50 | 75.73 | 43 | 51 | 58 | 63 | 67 | 72 | 77 | 83 | 92 | 0.0743 | 547 | 0.895 | 205.46 | 68.66 | 1 | 0.5041 | 560 | 0.0025 | 26.29 | 6.146 | 0.2030 | 4951.3 | 386036 | 31800000 | 2760000000 | 0.4919 | 0.1558 | 0.0017 | 0.0000 | 0.0084 | 0.0000 | 0.0506 | 0.0042 | 0.0759 | 0.0116 | 0.1433 | 0.0582 | 0.1855 | 0.0857 | 0.1484 | 0.1228 | 0.2024 | 0.1185 | 0.1838 | 0.5989 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0237 | 0.0078 | 0.0580 | 0.0447 | 0.1018 | 0.0438 | 0.0994 | 0.0720 | 0.1515 | 0.0730 | 0.5657 | 0.7588 | 0.0198 | 0.0241 | 0.0238 | 0.0361 | 0.0437 | 0.1566 | 0.1032 | 0.2289 | 0.1468 | 0.1325 | 0.2103 | 0.1687 | 0.1071 | 0.0602 | 0.1151 | 0.0482 | 0.2302 | 0.1446 | 0.0000 | 0.0036 | 0.0163 | 0.0470 | 0.1501 | 0.1410 | 0.1338 | 0.1591 | 0.3490 | 15 | 17 | 18 | 21 | 24 | 29 | 39 | 59 | 117 | 0.2303 | 3.57 | 2.698 | 0.7805 | 8387.2 | 2780000 | 1260000000 | 683000000000 | 0.4695 | 0.1988 | 0.0338 | 0.0076 | 0.1132 | 0.0146 | 0.2294 | 0.0419 | 0.1779 | 0.1017 | 0.1647 | 0.1773 | 0.1250 | 0.1919 | 0.0632 | 0.1582 | 0.0662 | 0.1264 | 0.0265 | 0.1804 | 0.0057 | 0.0035 | 0.0047 | 0.0053 | 0.0095 | 0.0114 | 0.0218 | 0.0252 | 0.0816 | 0.0650 | 0.1044 | 0.0919 | 0.0745 | 0.0831 | 0.1144 | 0.1136 | 0.5833 | 0.6010 | 0.0007 | 0.0016 | 0.0042 | 0.0032 | 0.0049 | 0.0048 | 0.0329 | 0.0322 | 0.0988 | 0.0893 | 0.1142 | 0.1376 | 0.0883 | 0.0837 | 0.1065 | 0.1255 | 0.5494 | 0.5221 | 0.0029 | 0.0041 | 0.0088 | 0.0269 | 0.0779 | 0.1265 | 0.0715 | 0.1154 | 0.5659 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1158 | 547 | | 3628 | 6182 | 70.1 | 18.21 | 293.38 | 247.61 | 48 | 56 | 61 | 65 | 68 | 73 | 77 | 84 | 93 | 0.1234 | 763 | 0.764 | 96.33 | 26.17 | 2 | 0.0714 | 259 | 0.0063 | 7.41 | 5.408 | 0.3836 | 5245.5 | 419586 | 36100000 | 3360000000 | 0.4909 | 0.1773 | 0.0023 | 0.0000 | 0.0055 | 0.0006 | 0.0137 | 0.0022 | 0.0339 | 0.0099 | 0.0870 | 0.0304 | 0.1612 | 0.0565 | 0.1658 | 0.0624 | 0.1557 | 0.1052 | 0.3750 | 0.7327 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0021 | 0.0006 | 0.0086 | 0.0049 | 0.0429 | 0.0204 | 0.0689 | 0.0357 | 0.0703 | 0.0319 | 0.0998 | 0.0512 | 0.7071 | 0.8550 | 0.0014 | 0.0156 | 0.0205 | 0.0156 | 0.0533 | 0.1172 | 0.0861 | 0.1367 | 0.1516 | 0.1797 | 0.1954 | 0.1680 | 0.1175 | 0.1016 | 0.1434 | 0.0977 | 0.2309 | 0.1680 | 0.0029 | 0.0041 | 0.0140 | 0.0479 | 0.0918 | 0.1350 | 0.1227 | 0.1508 | 0.4307 | 31 | 70 | 122 | 175 | 230 | 293 | 376 | 483 | 655 | 0.0026 | 110.17 | 7.306 | 0.2160 | 147376.0 | 96400000 | 74100000000 | 63400000000000 | 0.5179 | 0.1541 | 0.0174 | 0.0019 | 0.0872 | 0.0087 | 0.1851 | 0.0367 | 0.1986 | 0.0783 | 0.1928 | 0.1522 | 0.1415 | 0.2011 | 0.0688 | 0.1609 | 0.0736 | 0.1542 | 0.0349 | 0.2059 | 0.0013 | 0.0005 | 0.0023 | 0.0022 | 0.0085 | 0.0027 | 0.0214 | 0.0121 | 0.0628 | 0.0486 | 0.0986 | 0.0955 | 0.0832 | 0.0720 | 0.1216 | 0.1055 | 0.6003 | 0.6608 | 0.0015 | 0.0037 | 0.0040 | 0.0086 | 0.0119 | 0.0165 | 0.0308 | 0.0354 | 0.0826 | 0.0886 | 0.1323 | 0.1405 | 0.0930 | 0.1069 | 0.1264 | 0.1497 | 0.5174 | 0.4502 | 0.0012 | 0.0016 | 0.0113 | 0.0311 | 0.0638 | 0.1179 | 0.0973 | 0.1179 | 0.5579 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 202 | 300 | | 6785 | 14162 | 73.6 | 17.99 | 128.75 | 204.22 | 55 | 60 | 64 | 67 | 70 | 74 | 78 | 85 | 98 | 0.0703 | 996 | 0.964 | 72.80 | 24.35 | 1 | 0.0280 | 190 | 0.0034 | 16.24 | 6.105 | 0.2850 | 5739.9 | 477688 | 42700000 | 4120000000 | 0.4408 | 0.2110 | 0.0005 | 0.0000 | 0.0039 | 0.0005 | 0.0122 | 0.0021 | 0.0270 | 0.0047 | 0.0766 | 0.0226 | 0.1354 | 0.0389 | 0.1541 | 0.0501 | 0.2125 | 0.0784 | 0.3779 | 0.8028 | 0.0002 | 0.0000 | 0.0015 | 0.0001 | 0.0044 | 0.0000 | 0.0115 | 0.0003 | 0.0412 | 0.0127 | 0.0738 | 0.0228 | 0.0842 | 0.0195 | 0.1337 | 0.0408 | 0.6495 | 0.9038 | 0.0089 | 0.0082 | 0.0124 | 0.0392 | 0.0231 | 0.0351 | 0.0738 | 0.1072 | 0.1120 | 0.1691 | 0.1431 | 0.1794 | 0.1182 | 0.1381 | 0.1476 | 0.1196 | 0.3609 | 0.2041 | 0.0051 | 0.0116 | 0.0260 | 0.0619 | 0.0952 | 0.1284 | 0.1208 | 0.1302 | 0.4208 | 12 | 14 | 16 | 19 | 29 | 64 | 131 | 219 | 365 | 0.0796 | 32.45 | 4.690 | 0.5502 | 58277.5 | 46900000 | 56200000000 | 88300000000000 | 0.5837 | 0.1324 | 0.0408 | 0.0021 | 0.1841 | 0.0191 | 0.2326 | 0.0908 | 0.1830 | 0.1300 | 0.1709 | 0.1990 | 0.1158 | 0.1879 | 0.0364 | 0.1423 | 0.0254 | 0.1147 | 0.0110 | 0.1141 | 0.0008 | 0.0004 | 0.0008 | 0.0017 | 0.0017 | 0.0017 | 0.0080 | 0.0075 | 0.0431 | 0.0368 | 0.0772 | 0.0632 | 0.0574 | 0.0462 | 0.1056 | 0.0896 | 0.7054 | 0.7529 | 0.0008 | 0.0006 | 0.0008 | 0.0020 | 0.0029 | 0.0050 | 0.0130 | 0.0190 | 0.0619 | 0.0781 | 0.1060 | 0.1085 | 0.0824 | 0.0930 | 0.1331 | 0.1355 | 0.5993 | 0.5582 | 0.0000 | 0.0009 | 0.0016 | 0.0108 | 0.0498 | 0.0912 | 0.0683 | 0.1170 | 0.6604 |