High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1142 | 857 | | 7401 | 14616 | 171.0 | 66.26 | 71.29 | 133.72 | 97 | 113 | 126 | 141 | 159 | 177 | 198 | 227 | 267 | 0.0757 | 1106 | 0.455 | 200.25 | 41.00 | 7 | 0.0947 | 701 | 0.0014 | 22.02 | 6.984 | 0.2885 | 33621.9 | 7480000 | 1840000000 | 492000000000 | 0.3427 | 0.2805 | 0.0023 | 0.0008 | 0.0023 | 0.0025 | 0.0164 | 0.0059 | 0.0279 | 0.0086 | 0.0707 | 0.0301 | 0.1250 | 0.0604 | 0.1170 | 0.0539 | 0.1514 | 0.0722 | 0.4868 | 0.7658 | 0.0004 | 0.0005 | 0.0013 | 0.0012 | 0.0054 | 0.0022 | 0.0073 | 0.0043 | 0.0207 | 0.0130 | 0.0326 | 0.0254 | 0.0318 | 0.0221 | 0.0443 | 0.0300 | 0.8561 | 0.9014 | 0.0010 | 0.0000 | 0.0030 | 0.0041 | 0.0094 | 0.0058 | 0.0189 | 0.0386 | 0.0506 | 0.0641 | 0.0839 | 0.1191 | 0.0645 | 0.0994 | 0.0948 | 0.1224 | 0.6738 | 0.5464 | 0.0012 | 0.0025 | 0.0065 | 0.0109 | 0.0349 | 0.0477 | 0.0514 | 0.0767 | 0.7681 | 10 | 12 | 14 | 16 | 20 | 33 | 59 | 100 | 185 | 0.1556 | 7.37 | 3.609 | 0.6941 | 22963.2 | 18300000 | 21700000000 | 29800000000000 | 0.5623 | 0.1121 | 0.0192 | 0.0013 | 0.1028 | 0.0217 | 0.1742 | 0.0579 | 0.2030 | 0.0744 | 0.1838 | 0.1431 | 0.1324 | 0.1783 | 0.0941 | 0.1601 | 0.0662 | 0.1353 | 0.0244 | 0.2279 | 0.0000 | 0.0002 | 0.0020 | 0.0025 | 0.0051 | 0.0046 | 0.0151 | 0.0122 | 0.0523 | 0.0408 | 0.0785 | 0.0615 | 0.0621 | 0.0522 | 0.0923 | 0.0762 | 0.6926 | 0.7500 | 0.0006 | 0.0003 | 0.0012 | 0.0037 | 0.0062 | 0.0075 | 0.0211 | 0.0251 | 0.0699 | 0.0728 | 0.1077 | 0.1162 | 0.0759 | 0.0799 | 0.1107 | 0.1118 | 0.6067 | 0.5827 | 0.0003 | 0.0008 | 0.0031 | 0.0230 | 0.0637 | 0.0872 | 0.0730 | 0.0993 | 0.6497 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 954 | 880 | | 1679 | 5441 | 653.6 | 119.11 | 75.62 | 146.47 | 478 | 542 | 591 | 627 | 661 | 696 | 731 | 766 | 800 | 0.0884 | 481 | 0.755 | 132.23 | 36.35 | 1 | 0.2287 | 384 | 0.0009 | 82.04 | 7.094 | 0.1478 | 441315.0 | 307000000 | 218000000000 | 159000000000000 | 0.3946 | 0.2342 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0086 | 0.0018 | 0.0522 | 0.0283 | 0.0779 | 0.0361 | 0.0693 | 0.0307 | 0.1259 | 0.0451 | 0.6652 | 0.8581 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0018 | 0.0313 | 0.0281 | 0.0392 | 0.0329 | 0.0271 | 0.0257 | 0.0499 | 0.0418 | 0.8504 | 0.8698 | 0.0042 | 0.0000 | 0.0169 | 0.0000 | 0.0254 | 0.0000 | 0.0424 | 0.0000 | 0.0890 | 0.0000 | 0.1271 | 0.0000 | 0.1144 | 0.0000 | 0.1271 | 0.0000 | 0.4534 | 0.0000 | 0.0011 | 0.0011 | 0.0034 | 0.0103 | 0.0525 | 0.0627 | 0.0490 | 0.0855 | 0.7343 | 7 | 9 | 11 | 13 | 17 | 28 | 60 | 104 | 173 | 0.0733 | 1.76 | 2.761 | 0.5531 | 27168.4 | 17800000 | 14800000000 | 13800000000000 | 0.4065 | 0.2202 | 0.0128 | 0.0026 | 0.0204 | 0.0102 | 0.0510 | 0.0269 | 0.1301 | 0.0409 | 0.1913 | 0.0882 | 0.2041 | 0.1317 | 0.1735 | 0.1228 | 0.1301 | 0.2008 | 0.0867 | 0.3760 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0018 | 0.0027 | 0.0092 | 0.0070 | 0.0308 | 0.0271 | 0.0450 | 0.0411 | 0.0431 | 0.0319 | 0.0603 | 0.0541 | 0.8097 | 0.8343 | 0.0008 | 0.0009 | 0.0000 | 0.0019 | 0.0049 | 0.0075 | 0.0130 | 0.0160 | 0.0381 | 0.0479 | 0.0657 | 0.0695 | 0.0536 | 0.0638 | 0.0869 | 0.0892 | 0.7370 | 0.7033 | 0.0000 | 0.0063 | 0.0042 | 0.0105 | 0.0359 | 0.0450 | 0.0549 | 0.0703 | 0.7729 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 209 | 570 | | 4703 | 11257 | 455.0 | 77.10 | 137.18 | 277.92 | 340 | 398 | 427 | 444 | 459 | 475 | 493 | 516 | 549 | 0.0636 | 716 | 0.833 | 89.36 | 25.02 | 3 | 0.0515 | 242 | 0.0019 | 16.09 | 6.616 | 0.2886 | 212933.0 | 102000000 | 50100000000 | 25100000000000 | 0.4498 | 0.1891 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0011 | 0.0002 | 0.0053 | 0.0006 | 0.0283 | 0.0153 | 0.0415 | 0.0267 | 0.0404 | 0.0162 | 0.0569 | 0.0265 | 0.8258 | 0.9144 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0006 | 0.0175 | 0.0150 | 0.0253 | 0.0249 | 0.0212 | 0.0146 | 0.0305 | 0.0226 | 0.9033 | 0.9222 | 0.0040 | 0.0000 | 0.0120 | 0.1429 | 0.0080 | 0.2143 | 0.0300 | 0.1429 | 0.0580 | 0.2857 | 0.0920 | 0.1429 | 0.0820 | 0.0714 | 0.0900 | 0.0000 | 0.6240 | 0.0000 | 0.0032 | 0.0069 | 0.0105 | 0.0242 | 0.0395 | 0.0492 | 0.0629 | 0.0786 | 0.7251 | 9 | 11 | 13 | 15 | 18 | 27 | 60 | 180 | 452 | 0.1894 | 29.54 | 3.820 | 0.6610 | 96051.8 | 107000000 | 152000000000 | 257000000000000 | 0.3706 | 0.2754 | 0.0734 | 0.0034 | 0.1353 | 0.0339 | 0.2638 | 0.1141 | 0.1789 | 0.1548 | 0.1628 | 0.1390 | 0.0757 | 0.1921 | 0.0436 | 0.1209 | 0.0367 | 0.1028 | 0.0298 | 0.1390 | 0.0004 | 0.0000 | 0.0007 | 0.0010 | 0.0032 | 0.0010 | 0.0140 | 0.0094 | 0.0415 | 0.0439 | 0.0727 | 0.0638 | 0.0466 | 0.0449 | 0.0659 | 0.0651 | 0.7550 | 0.7708 | 0.0000 | 0.0000 | 0.0034 | 0.0014 | 0.0038 | 0.0027 | 0.0089 | 0.0119 | 0.0539 | 0.0562 | 0.0883 | 0.0965 | 0.0526 | 0.0562 | 0.0870 | 0.0942 | 0.7020 | 0.6808 | 0.0004 | 0.0012 | 0.0019 | 0.0105 | 0.0487 | 0.0790 | 0.0487 | 0.0821 | 0.7275 | ||
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 828 | 731 | | 4916 | 17078 | 344.5 | 49.98 | 70.06 | 109.17 | 278 | 302 | 316 | 330 | 344 | 358 | 374 | 391 | 410 | 0.0440 | 752 | 0.700 | 121.80 | 29.61 | 2 | 0.0728 | 358 | 0.0032 | 8.09 | 6.021 | 0.3596 | 121208.0 | 43500000 | 15900000000 | 5900000000000 | 0.4249 | 0.2173 | 0.0002 | 0.0000 | 0.0015 | 0.0000 | 0.0045 | 0.0000 | 0.0067 | 0.0000 | 0.0270 | 0.0128 | 0.0399 | 0.0214 | 0.0394 | 0.0128 | 0.0789 | 0.0218 | 0.8018 | 0.9312 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0027 | 0.0000 | 0.0144 | 0.0128 | 0.0229 | 0.0214 | 0.0200 | 0.0128 | 0.0328 | 0.0185 | 0.9062 | 0.9345 | 0.0187 | 1.0000 | 0.0258 | 0.0000 | 0.0328 | 0.0000 | 0.0562 | 0.0000 | 0.1007 | 0.0000 | 0.1499 | 0.0000 | 0.1288 | 0.0000 | 0.1241 | 0.0000 | 0.3630 | 0.0000 | 0.0021 | 0.0041 | 0.0062 | 0.0144 | 0.0299 | 0.0533 | 0.0545 | 0.0685 | 0.7671 | 6 | 8 | 10 | 11 | 14 | 26 | 60 | 123 | 221 | 0.1196 | 5.30 | 3.437 | 0.5812 | 16825.5 | 6090000 | 2810000000 | 1590000000000 | 0.3847 | 0.2364 | 0.0327 | 0.0062 | 0.1401 | 0.0166 | 0.2424 | 0.0916 | 0.2139 | 0.1211 | 0.1718 | 0.1868 | 0.1149 | 0.2002 | 0.0516 | 0.1454 | 0.0263 | 0.1174 | 0.0063 | 0.1148 | 0.0000 | 0.0005 | 0.0006 | 0.0010 | 0.0023 | 0.0019 | 0.0083 | 0.0103 | 0.0391 | 0.0317 | 0.0712 | 0.0567 | 0.0463 | 0.0437 | 0.0805 | 0.0695 | 0.7518 | 0.7849 | 0.0000 | 0.0000 | 0.0009 | 0.0013 | 0.0021 | 0.0033 | 0.0145 | 0.0170 | 0.0532 | 0.0625 | 0.0907 | 0.0938 | 0.0628 | 0.0780 | 0.0937 | 0.1001 | 0.6822 | 0.6441 | 0.0004 | 0.0002 | 0.0032 | 0.0122 | 0.0464 | 0.0780 | 0.0622 | 0.0900 | 0.7075 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 987 | 380 | | 12791 | 25828 | 244.0 | 56.67 | 95.18 | 198.31 | 177 | 201 | 217 | 230 | 243 | 256 | 271 | 289 | 316 | 0.0428 | 1106 | 0.611 | 50.00 | 6.08 | 2 | 0.0081 | 104 | 0.0009 | 41.29 | 7.385 | 0.1837 | 62748.8 | 16900000 | 4720000000 | 1370000000000 | 0.4150 | 0.2225 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0040 | 0.0001 | 0.0139 | 0.0020 | 0.0437 | 0.0128 | 0.0935 | 0.0267 | 0.1037 | 0.0271 | 0.1485 | 0.0436 | 0.5911 | 0.8877 | 0.0004 | 0.0000 | 0.0005 | 0.0000 | 0.0012 | 0.0000 | 0.0051 | 0.0007 | 0.0167 | 0.0075 | 0.0370 | 0.0142 | 0.0370 | 0.0105 | 0.0578 | 0.0186 | 0.8443 | 0.9484 | 0.0051 | 0.0074 | 0.0136 | 0.0297 | 0.0230 | 0.0408 | 0.0519 | 0.1169 | 0.0928 | 0.1447 | 0.1328 | 0.1855 | 0.0992 | 0.1039 | 0.1507 | 0.1169 | 0.4308 | 0.2542 | 0.0013 | 0.0041 | 0.0084 | 0.0209 | 0.0523 | 0.0900 | 0.0917 | 0.1156 | 0.6157 | 10 | 11 | 13 | 16 | 19 | 30 | 61 | 128 | 252 | 0.1445 | 34.06 | 4.024 | 0.6355 | 48384.8 | 50100000 | 70500000000 | 115000000000000 | 0.4211 | 0.2561 | 0.0753 | 0.0013 | 0.2507 | 0.0276 | 0.3011 | 0.1619 | 0.1172 | 0.1639 | 0.1051 | 0.2101 | 0.0717 | 0.1905 | 0.0362 | 0.0921 | 0.0291 | 0.0768 | 0.0135 | 0.0758 | 0.0001 | 0.0002 | 0.0003 | 0.0001 | 0.0021 | 0.0012 | 0.0147 | 0.0116 | 0.0679 | 0.0616 | 0.1162 | 0.1005 | 0.0657 | 0.0596 | 0.1024 | 0.0930 | 0.6306 | 0.6721 | 0.0002 | 0.0012 | 0.0012 | 0.0028 | 0.0041 | 0.0058 | 0.0225 | 0.0271 | 0.0797 | 0.0776 | 0.1234 | 0.1387 | 0.0808 | 0.0856 | 0.1154 | 0.1264 | 0.5727 | 0.5349 | 0.0002 | 0.0013 | 0.0034 | 0.0168 | 0.0750 | 0.1186 | 0.0738 | 0.1066 | 0.6045 | ||
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 903 | 431 | | 54613 | 82874 | 84.8 | 46.65 | 114.00 | 205.41 | 23 | 28 | 54 | 73 | 87 | 99 | 112 | 126 | 146 | 0.0303 | 2514 | 0.607 | 231.82 | 52.47 | 24 | 0.0118 | 645 | 0.0046 | 13.65 | 6.351 | 0.3627 | 9367.0 | 1190000 | 165000000 | 24700000000 | 0.5125 | 0.1476 | 0.0017 | 0.0007 | 0.0076 | 0.0010 | 0.0380 | 0.0040 | 0.0801 | 0.0150 | 0.1435 | 0.0575 | 0.1828 | 0.1084 | 0.1675 | 0.1062 | 0.1626 | 0.1362 | 0.2163 | 0.5709 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0014 | 0.0002 | 0.0055 | 0.0015 | 0.0213 | 0.0119 | 0.0388 | 0.0234 | 0.0374 | 0.0198 | 0.0551 | 0.0316 | 0.8399 | 0.9117 | 0.0006 | 0.0018 | 0.0028 | 0.0048 | 0.0065 | 0.0130 | 0.0229 | 0.0391 | 0.0576 | 0.0808 | 0.0882 | 0.1189 | 0.0857 | 0.0985 | 0.1117 | 0.1228 | 0.6241 | 0.5203 | 0.0004 | 0.0014 | 0.0040 | 0.0124 | 0.0339 | 0.0605 | 0.0589 | 0.0824 | 0.7461 | 10 | 12 | 13 | 15 | 18 | 26 | 61 | 174 | 383 | 0.2390 | 19.16 | 3.787 | 0.6638 | 55186.4 | 40400000 | 36400000000 | 37700000000000 | 0.4605 | 0.1949 | 0.1576 | 0.0035 | 0.3814 | 0.0611 | 0.3071 | 0.3277 | 0.0839 | 0.2234 | 0.0408 | 0.1726 | 0.0158 | 0.1086 | 0.0071 | 0.0487 | 0.0039 | 0.0298 | 0.0026 | 0.0245 | 0.0001 | 0.0001 | 0.0006 | 0.0003 | 0.0013 | 0.0008 | 0.0117 | 0.0106 | 0.0652 | 0.0602 | 0.1027 | 0.0939 | 0.0640 | 0.0575 | 0.0983 | 0.0881 | 0.6561 | 0.6885 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0020 | 0.0025 | 0.0164 | 0.0184 | 0.0742 | 0.0778 | 0.1173 | 0.1225 | 0.0764 | 0.0817 | 0.1085 | 0.1098 | 0.6044 | 0.5860 | 0.0001 | 0.0002 | 0.0017 | 0.0132 | 0.0722 | 0.1105 | 0.0693 | 0.1056 | 0.6272 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 430 | | 9439 | 30387 | 187.6 | 49.18 | 85.43 | 137.20 | 127 | 150 | 163 | 176 | 187 | 199 | 211 | 226 | 249 | 0.0448 | 1360 | 0.978 | 133.06 | 44.05 | 3 | 0.0366 | 345 | 0.0011 | 36.27 | 7.174 | 0.1963 | 37625.0 | 7970000 | 1770000000 | 413000000000 | 0.4260 | 0.2189 | 0.0002 | 0.0000 | 0.0009 | 0.0001 | 0.0043 | 0.0007 | 0.0199 | 0.0027 | 0.0634 | 0.0169 | 0.1233 | 0.0399 | 0.1423 | 0.0401 | 0.1734 | 0.0580 | 0.4723 | 0.8415 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0072 | 0.0010 | 0.0225 | 0.0102 | 0.0434 | 0.0235 | 0.0516 | 0.0149 | 0.0628 | 0.0250 | 0.8102 | 0.9254 | 0.0063 | 0.0066 | 0.0083 | 0.0115 | 0.0276 | 0.0508 | 0.0683 | 0.0869 | 0.1017 | 0.1328 | 0.1424 | 0.1410 | 0.1226 | 0.1016 | 0.1346 | 0.1279 | 0.3881 | 0.3410 | 0.0009 | 0.0032 | 0.0071 | 0.0234 | 0.0626 | 0.0939 | 0.0934 | 0.1316 | 0.5841 | 10 | 12 | 14 | 16 | 20 | 29 | 62 | 140 | 267 | 0.1579 | 16.30 | 3.924 | 0.6407 | 26120.0 | 12600000 | 7750000000 | 5660000000000 | 0.5727 | 0.1271 | 0.1171 | 0.0076 | 0.2705 | 0.0420 | 0.2342 | 0.2186 | 0.1164 | 0.1757 | 0.1023 | 0.1567 | 0.0686 | 0.1384 | 0.0444 | 0.0856 | 0.0316 | 0.0752 | 0.0148 | 0.1002 | 0.0003 | 0.0005 | 0.0015 | 0.0008 | 0.0032 | 0.0031 | 0.0147 | 0.0133 | 0.0655 | 0.0528 | 0.0960 | 0.0906 | 0.0648 | 0.0549 | 0.0997 | 0.0876 | 0.6543 | 0.6964 | 0.0001 | 0.0004 | 0.0007 | 0.0004 | 0.0029 | 0.0039 | 0.0241 | 0.0258 | 0.0759 | 0.0823 | 0.1193 | 0.1295 | 0.0787 | 0.0827 | 0.1092 | 0.1138 | 0.5892 | 0.5612 | 0.0004 | 0.0010 | 0.0023 | 0.0194 | 0.0694 | 0.1084 | 0.0725 | 0.1053 | 0.6214 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 179 | 861 | | 6894 | 24993 | 432.7 | 77.04 | 123.09 | 229.52 | 337 | 363 | 385 | 406 | 427 | 448 | 470 | 497 | 536 | 0.0541 | 1352 | 1.247 | 106.10 | 42.20 | 2 | 0.0392 | 270 | 0.0024 | 14.62 | 6.292 | 0.2830 | 193164.0 | 88900000 | 42200000000 | 20600000000000 | 0.4573 | 0.1908 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0034 | 0.0000 | 0.0121 | 0.0006 | 0.0472 | 0.0149 | 0.0960 | 0.0253 | 0.1212 | 0.0267 | 0.1545 | 0.0354 | 0.5647 | 0.8972 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0065 | 0.0001 | 0.0253 | 0.0121 | 0.0467 | 0.0177 | 0.0549 | 0.0126 | 0.0783 | 0.0167 | 0.7863 | 0.9408 | 0.0053 | 0.0000 | 0.0160 | 0.0701 | 0.0299 | 0.0764 | 0.0812 | 0.1783 | 0.1335 | 0.1720 | 0.1656 | 0.1783 | 0.1186 | 0.1274 | 0.1346 | 0.0955 | 0.3152 | 0.1019 | 0.0009 | 0.0037 | 0.0079 | 0.0244 | 0.0711 | 0.1200 | 0.1053 | 0.1236 | 0.5430 | 8 | 10 | 12 | 13 | 16 | 23 | 63 | 188 | 422 | 0.2078 | 29.75 | 3.972 | 0.6370 | 67827.8 | 55500000 | 55600000000 | 63900000000000 | 0.4521 | 0.1694 | 0.1333 | 0.0042 | 0.3651 | 0.0371 | 0.3035 | 0.2123 | 0.1120 | 0.2751 | 0.0504 | 0.2537 | 0.0202 | 0.1124 | 0.0090 | 0.0570 | 0.0045 | 0.0314 | 0.0022 | 0.0167 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0014 | 0.0008 | 0.0135 | 0.0108 | 0.0527 | 0.0490 | 0.0825 | 0.0789 | 0.0578 | 0.0500 | 0.0808 | 0.0738 | 0.7110 | 0.7365 | 0.0002 | 0.0004 | 0.0009 | 0.0010 | 0.0018 | 0.0029 | 0.0147 | 0.0130 | 0.0575 | 0.0617 | 0.0963 | 0.1072 | 0.0686 | 0.0675 | 0.0945 | 0.1032 | 0.6655 | 0.6432 | 0.0007 | 0.0005 | 0.0013 | 0.0119 | 0.0549 | 0.0931 | 0.0549 | 0.0860 | 0.6968 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 968 | 293 | | 9056 | 13099 | 516.1 | 88.24 | 114.69 | 251.28 | 396 | 459 | 491 | 512 | 529 | 545 | 562 | 583 | 612 | 0.0837 | 1097 | 0.940 | 103.45 | 28.16 | 6 | 0.0282 | 255 | 0.0009 | 51.99 | 7.361 | 0.1986 | 274112.0 | 149000000 | 82200000000 | 46100000000000 | 0.4370 | 0.2059 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0050 | 0.0007 | 0.0278 | 0.0152 | 0.0543 | 0.0277 | 0.0482 | 0.0150 | 0.0760 | 0.0288 | 0.7879 | 0.9127 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0007 | 0.0168 | 0.0152 | 0.0317 | 0.0272 | 0.0203 | 0.0143 | 0.0351 | 0.0258 | 0.8942 | 0.9168 | 0.0106 | 0.0000 | 0.0080 | 0.0000 | 0.0359 | 0.0000 | 0.0638 | 0.0000 | 0.1237 | 0.0000 | 0.1463 | 0.0000 | 0.1077 | 0.0000 | 0.1303 | 0.0000 | 0.3737 | 0.0000 | 0.0015 | 0.0017 | 0.0063 | 0.0160 | 0.0428 | 0.0699 | 0.0713 | 0.1070 | 0.6836 | 8 | 10 | 12 | 14 | 20 | 34 | 63 | 120 | 305 | 0.0778 | 7.79 | 3.212 | 0.5546 | 76290.7 | 93700000 | 170000000000 | 429000000000000 | 0.7394 | 0.0357 | 0.0196 | 0.0006 | 0.0825 | 0.0106 | 0.1649 | 0.0417 | 0.1872 | 0.0636 | 0.1702 | 0.1514 | 0.1584 | 0.2125 | 0.1152 | 0.1383 | 0.0654 | 0.1383 | 0.0366 | 0.2430 | 0.0003 | 0.0000 | 0.0019 | 0.0013 | 0.0083 | 0.0037 | 0.0156 | 0.0088 | 0.0568 | 0.0470 | 0.0879 | 0.0948 | 0.0632 | 0.0564 | 0.0959 | 0.0866 | 0.6702 | 0.7013 | 0.0008 | 0.0005 | 0.0004 | 0.0014 | 0.0059 | 0.0028 | 0.0184 | 0.0229 | 0.0675 | 0.0744 | 0.1010 | 0.1155 | 0.0700 | 0.0734 | 0.1014 | 0.1001 | 0.6345 | 0.6090 | 0.0015 | 0.0018 | 0.0041 | 0.0170 | 0.0595 | 0.0983 | 0.0698 | 0.0953 | 0.6526 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 209 | 861 | | 543 | 4357 | 152.9 | 32.22 | 90.49 | 146.81 | 112 | 125 | 134 | 144 | 152 | 161 | 170 | 181 | 194 | 0.0925 | 403 | 1.074 | 82.81 | 25.61 | 1 | 0.3665 | 199 | 0.0040 | 21.07 | 5.680 | 0.2454 | 24410.0 | 4050000 | 697000000 | 124000000000 | 0.4295 | 0.2088 | 0.0000 | 0.0000 | 0.0029 | 0.0000 | 0.0029 | 0.0000 | 0.0632 | 0.0078 | 0.1523 | 0.0447 | 0.1638 | 0.0953 | 0.1868 | 0.0700 | 0.1782 | 0.1498 | 0.2500 | 0.6323 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0000 | 0.0000 | 0.0156 | 0.0075 | 0.0690 | 0.0413 | 0.0980 | 0.0732 | 0.0802 | 0.0450 | 0.1114 | 0.0994 | 0.6236 | 0.7336 | 0.0198 | 0.0000 | 0.0099 | 0.0000 | 0.0891 | 0.1053 | 0.1089 | 0.3684 | 0.1782 | 0.3684 | 0.1188 | 0.0526 | 0.1584 | 0.1053 | 0.1386 | 0.0000 | 0.1782 | 0.0000 | 0.0000 | 0.0075 | 0.0491 | 0.0340 | 0.1132 | 0.1208 | 0.1094 | 0.1245 | 0.4415 | 6 | 7 | 9 | 10 | 12 | 26 | 64 | 155 | 335 | 0.1505 | 5.85 | 3.608 | 0.6197 | 29737.3 | 12900000 | 6260000000 | 3270000000000 | 0.5075 | 0.1310 | 0.0714 | 0.0045 | 0.1939 | 0.0201 | 0.2041 | 0.0447 | 0.2857 | 0.1029 | 0.1276 | 0.2282 | 0.0867 | 0.2371 | 0.0255 | 0.1365 | 0.0051 | 0.1275 | 0.0000 | 0.0984 | 0.0016 | 0.0014 | 0.0008 | 0.0000 | 0.0016 | 0.0007 | 0.0195 | 0.0114 | 0.0568 | 0.0549 | 0.0860 | 0.0834 | 0.0543 | 0.0499 | 0.0933 | 0.0848 | 0.6861 | 0.7135 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0031 | 0.0145 | 0.0157 | 0.0685 | 0.0680 | 0.0858 | 0.0931 | 0.0559 | 0.0596 | 0.1022 | 0.1004 | 0.6702 | 0.6600 | 0.0009 | 0.0000 | 0.0027 | 0.0089 | 0.0608 | 0.0956 | 0.0536 | 0.0903 | 0.6872 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 547 | 120 | | 5210 | 7031 | 116.5 | 33.51 | 67.29 | 88.49 | 82 | 90 | 96 | 102 | 109 | 116 | 126 | 140 | 161 | 0.1074 | 755 | 0.962 | 86.27 | 33.84 | 2 | 0.0478 | 249 | 0.0029 | 20.97 | 6.262 | 0.2723 | 14702.5 | 2030000 | 306000000 | 50600000000 | 0.4062 | 0.2387 | 0.0018 | 0.0000 | 0.0032 | 0.0000 | 0.0093 | 0.0009 | 0.0370 | 0.0017 | 0.1025 | 0.0273 | 0.1787 | 0.0577 | 0.1630 | 0.0624 | 0.1798 | 0.0955 | 0.3247 | 0.7545 | 0.0010 | 0.0000 | 0.0021 | 0.0000 | 0.0044 | 0.0004 | 0.0154 | 0.0008 | 0.0427 | 0.0160 | 0.0740 | 0.0248 | 0.0717 | 0.0220 | 0.1040 | 0.0419 | 0.6847 | 0.8941 | 0.0019 | 0.0042 | 0.0049 | 0.0166 | 0.0165 | 0.0374 | 0.0525 | 0.0832 | 0.1380 | 0.1933 | 0.1672 | 0.2121 | 0.1263 | 0.0894 | 0.1545 | 0.1538 | 0.3382 | 0.2100 | 0.0039 | 0.0048 | 0.0101 | 0.0400 | 0.0761 | 0.1094 | 0.1104 | 0.1359 | 0.5094 | 12 | 15 | 20 | 26 | 33 | 43 | 64 | 100 | 163 | 0.0295 | 19.01 | 4.722 | 0.5549 | 12357.0 | 4090000 | 1840000000 | 978000000000 | 0.7256 | 0.0616 | 0.0176 | 0.0062 | 0.0821 | 0.0241 | 0.1437 | 0.0469 | 0.1935 | 0.0841 | 0.1686 | 0.1496 | 0.1569 | 0.1695 | 0.0997 | 0.1447 | 0.0982 | 0.1371 | 0.0396 | 0.2378 | 0.0025 | 0.0024 | 0.0050 | 0.0041 | 0.0103 | 0.0111 | 0.0227 | 0.0199 | 0.0900 | 0.0827 | 0.1399 | 0.1253 | 0.0929 | 0.0918 | 0.1312 | 0.1236 | 0.5056 | 0.5392 | 0.0011 | 0.0020 | 0.0092 | 0.0033 | 0.0075 | 0.0139 | 0.0316 | 0.0463 | 0.1086 | 0.1026 | 0.1580 | 0.1794 | 0.1080 | 0.1112 | 0.1356 | 0.1456 | 0.4406 | 0.3958 | 0.0034 | 0.0034 | 0.0112 | 0.0244 | 0.0937 | 0.1541 | 0.0941 | 0.1332 | 0.4824 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 944 | 643 | | 10766 | 25398 | 77.7 | 26.50 | 79.35 | 104.73 | 50 | 58 | 63 | 68 | 73 | 79 | 85 | 93 | 108 | 0.0568 | 1442 | 1.039 | 62.30 | 19.70 | 12 | 0.0144 | 155 | 0.0021 | 19.33 | 6.548 | 0.2687 | 6739.6 | 660302 | 73500000 | 9260000000 | 0.4514 | 0.1914 | 0.0004 | 0.0001 | 0.0041 | 0.0004 | 0.0155 | 0.0014 | 0.0404 | 0.0069 | 0.0933 | 0.0282 | 0.1426 | 0.0518 | 0.1465 | 0.0640 | 0.1811 | 0.0814 | 0.3762 | 0.7657 | 0.0003 | 0.0000 | 0.0017 | 0.0001 | 0.0045 | 0.0006 | 0.0160 | 0.0048 | 0.0422 | 0.0180 | 0.0703 | 0.0309 | 0.0638 | 0.0353 | 0.1024 | 0.0473 | 0.6987 | 0.8630 | 0.0039 | 0.0067 | 0.0111 | 0.0183 | 0.0261 | 0.0202 | 0.0623 | 0.0577 | 0.1044 | 0.0876 | 0.1358 | 0.1107 | 0.0894 | 0.0808 | 0.1049 | 0.1078 | 0.4621 | 0.5101 | 0.0018 | 0.0078 | 0.0155 | 0.0331 | 0.0750 | 0.0992 | 0.0965 | 0.1223 | 0.5488 | 24 | 27 | 31 | 34 | 39 | 47 | 64 | 99 | 187 | 0.1253 | 4.89 | 3.514 | 0.7026 | 17262.9 | 7360000 | 4380000000 | 3170000000000 | 0.5875 | 0.1331 | 0.0281 | 0.0053 | 0.1260 | 0.0156 | 0.1868 | 0.0425 | 0.1366 | 0.0966 | 0.1545 | 0.1560 | 0.1417 | 0.1683 | 0.1034 | 0.1305 | 0.0757 | 0.1316 | 0.0472 | 0.2536 | 0.0005 | 0.0026 | 0.0029 | 0.0056 | 0.0074 | 0.0082 | 0.0218 | 0.0211 | 0.0702 | 0.0565 | 0.0928 | 0.0744 | 0.0750 | 0.0686 | 0.1091 | 0.0987 | 0.6202 | 0.6644 | 0.0015 | 0.0009 | 0.0017 | 0.0024 | 0.0077 | 0.0079 | 0.0283 | 0.0323 | 0.0924 | 0.0996 | 0.1194 | 0.1287 | 0.0811 | 0.0910 | 0.1267 | 0.1337 | 0.5411 | 0.5034 | 0.0002 | 0.0021 | 0.0070 | 0.0280 | 0.0826 | 0.1089 | 0.0754 | 0.1199 | 0.5761 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 862 | 60 | | 536 | 8372 | 94.9 | 38.62 | 150.81 | 294.15 | 38 | 55 | 70 | 85 | 97 | 109 | 121 | 135 | 146 | 0.0688 | 576 | 0.456 | 105.65 | 21.93 | 2 | 0.7705 | 413 | 0.0025 | 45.30 | 6.078 | 0.1747 | 10500.4 | 1270000 | 163000000 | 21700000000 | 0.3490 | 0.2577 | 0.0000 | 0.0032 | 0.0057 | 0.0000 | 0.0345 | 0.0000 | 0.1149 | 0.0097 | 0.1782 | 0.0968 | 0.1782 | 0.1452 | 0.1322 | 0.1161 | 0.1379 | 0.1613 | 0.2184 | 0.4677 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0137 | 0.0024 | 0.0521 | 0.0471 | 0.0493 | 0.0659 | 0.0548 | 0.0329 | 0.0740 | 0.0776 | 0.7562 | 0.7741 | 0.0000 | 0.0000 | 0.0052 | 0.0000 | 0.0052 | 0.0087 | 0.0209 | 0.0435 | 0.0995 | 0.1130 | 0.0785 | 0.1130 | 0.1099 | 0.1217 | 0.1152 | 0.1739 | 0.5654 | 0.4261 | 0.0000 | 0.0000 | 0.0035 | 0.0142 | 0.0745 | 0.0816 | 0.0780 | 0.0957 | 0.6525 | 15 | 18 | 20 | 22 | 25 | 32 | 64 | 197 | 482 | 0.1543 | 30.36 | 3.816 | 0.6306 | 109258.0 | 124000000 | 171000000000 | 266000000000000 | 0.6017 | 0.0867 | 0.1678 | 0.0032 | 0.3557 | 0.0852 | 0.2550 | 0.2981 | 0.1040 | 0.2618 | 0.0570 | 0.1467 | 0.0336 | 0.1073 | 0.0201 | 0.0442 | 0.0067 | 0.0331 | 0.0000 | 0.0205 | 0.0010 | 0.0004 | 0.0025 | 0.0018 | 0.0029 | 0.0031 | 0.0152 | 0.0161 | 0.0678 | 0.0629 | 0.1130 | 0.0915 | 0.0683 | 0.0683 | 0.1170 | 0.1071 | 0.6123 | 0.6488 | 0.0006 | 0.0006 | 0.0012 | 0.0006 | 0.0069 | 0.0056 | 0.0242 | 0.0311 | 0.0806 | 0.0840 | 0.1163 | 0.1319 | 0.0996 | 0.0989 | 0.1232 | 0.1319 | 0.5475 | 0.5152 | 0.0011 | 0.0021 | 0.0037 | 0.0144 | 0.0880 | 0.1077 | 0.0859 | 0.1189 | 0.5781 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 372 | 900 | | 5044 | 9324 | 570.5 | 98.09 | 110.30 | 193.81 | 423 | 504 | 548 | 574 | 591 | 608 | 625 | 644 | 675 | 0.0741 | 691 | 0.949 | 144.16 | 41.87 | 3 | 0.0765 | 386 | 0.0009 | 58.08 | 7.313 | 0.1858 | 335121.0 | 201000000 | 123000000000 | 76200000000000 | 0.4530 | 0.1918 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0002 | 0.0055 | 0.0012 | 0.0271 | 0.0139 | 0.0472 | 0.0212 | 0.0462 | 0.0133 | 0.0650 | 0.0234 | 0.8066 | 0.9268 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0018 | 0.0012 | 0.0148 | 0.0139 | 0.0237 | 0.0212 | 0.0189 | 0.0133 | 0.0283 | 0.0218 | 0.9121 | 0.9285 | 0.0051 | 1.0000 | 0.0204 | 0.0000 | 0.0382 | 0.0000 | 0.0789 | 0.0000 | 0.1399 | 0.0000 | 0.1527 | 0.0000 | 0.1425 | 0.0000 | 0.1552 | 0.0000 | 0.2672 | 0.0000 | 0.0006 | 0.0016 | 0.0039 | 0.0132 | 0.0319 | 0.0631 | 0.0673 | 0.0879 | 0.7304 | 13 | 15 | 17 | 20 | 24 | 37 | 65 | 143 | 347 | 0.2499 | 4.68 | 3.068 | 0.7533 | 49725.0 | 35000000 | 30000000000 | 29200000000000 | 0.6863 | 0.0611 | 0.0201 | 0.0070 | 0.0828 | 0.0120 | 0.2081 | 0.0468 | 0.1834 | 0.0807 | 0.1969 | 0.1723 | 0.1454 | 0.1912 | 0.0805 | 0.1524 | 0.0403 | 0.1404 | 0.0425 | 0.1972 | 0.0004 | 0.0022 | 0.0004 | 0.0022 | 0.0021 | 0.0065 | 0.0116 | 0.0151 | 0.0418 | 0.0391 | 0.0708 | 0.0613 | 0.0472 | 0.0459 | 0.0911 | 0.0911 | 0.7345 | 0.7368 | 0.0000 | 0.0006 | 0.0005 | 0.0006 | 0.0051 | 0.0011 | 0.0142 | 0.0146 | 0.0524 | 0.0611 | 0.0956 | 0.0952 | 0.0478 | 0.0538 | 0.0935 | 0.0947 | 0.6909 | 0.6784 | 0.0000 | 0.0000 | 0.0019 | 0.0116 | 0.0551 | 0.0811 | 0.0487 | 0.0982 | 0.7034 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1203 | 196 | | 3608 | 1256 | 112.8 | 33.02 | 56.49 | 42.34 | 79 | 87 | 93 | 99 | 105 | 112 | 122 | 134 | 156 | 0.4076 | 512 | 0.975 | 95.35 | 33.06 | 2 | 0.0734 | 265 | 0.0032 | 16.99 | 6.143 | 0.2879 | 13822.0 | 1860000 | 276000000 | 45100000000 | 0.3979 | 0.2576 | 0.0010 | 0.0003 | 0.0065 | 0.0006 | 0.0176 | 0.0028 | 0.0391 | 0.0056 | 0.0918 | 0.0314 | 0.1565 | 0.0637 | 0.1590 | 0.0566 | 0.1951 | 0.0942 | 0.3335 | 0.7448 | 0.0004 | 0.0000 | 0.0026 | 0.0000 | 0.0097 | 0.0008 | 0.0164 | 0.0025 | 0.0421 | 0.0200 | 0.0742 | 0.0382 | 0.0753 | 0.0306 | 0.1037 | 0.0514 | 0.6755 | 0.8564 | 0.0102 | 0.0029 | 0.0116 | 0.0117 | 0.0277 | 0.0264 | 0.0524 | 0.0733 | 0.1252 | 0.1554 | 0.1514 | 0.1525 | 0.1208 | 0.1202 | 0.1339 | 0.1320 | 0.3668 | 0.3255 | 0.0035 | 0.0085 | 0.0148 | 0.0318 | 0.0890 | 0.1329 | 0.1025 | 0.1576 | 0.4594 | 20 | 26 | 31 | 37 | 45 | 55 | 65 | 79 | 102 | 0.0171 | 7.89 | 4.661 | 0.4707 | 4982.0 | 681992 | 133000000 | 33000000000 | 0.5597 | 0.0948 | 0.0435 | 0.0159 | 0.1268 | 0.0336 | 0.1739 | 0.0814 | 0.1775 | 0.1310 | 0.1920 | 0.1717 | 0.1522 | 0.1664 | 0.0942 | 0.1451 | 0.0254 | 0.1469 | 0.0145 | 0.1080 | 0.0016 | 0.0073 | 0.0126 | 0.0085 | 0.0316 | 0.0208 | 0.0411 | 0.0403 | 0.1785 | 0.1404 | 0.2054 | 0.2088 | 0.1627 | 0.1416 | 0.1769 | 0.1844 | 0.1896 | 0.2479 | 0.0056 | 0.0197 | 0.0364 | 0.0630 | 0.0756 | 0.0709 | 0.1064 | 0.1102 | 0.2269 | 0.2283 | 0.1961 | 0.1811 | 0.1064 | 0.1457 | 0.1457 | 0.1220 | 0.1008 | 0.0591 | 0.0021 | 0.0123 | 0.0452 | 0.0903 | 0.2074 | 0.2177 | 0.1561 | 0.1335 | 0.1355 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 912 | 233 | | 5870 | 24688 | 277.0 | 63.32 | 98.44 | 168.31 | 201 | 221 | 239 | 254 | 270 | 286 | 305 | 329 | 365 | 0.0475 | 1173 | 1.191 | 103.82 | 38.01 | 1 | 0.0428 | 251 | 0.0007 | 63.63 | 7.502 | 0.1601 | 80724.4 | 24700000 | 7930000000 | 2660000000000 | 0.4510 | 0.1942 | 0.0003 | 0.0002 | 0.0008 | 0.0000 | 0.0031 | 0.0002 | 0.0165 | 0.0020 | 0.0684 | 0.0184 | 0.1377 | 0.0460 | 0.1419 | 0.0408 | 0.1640 | 0.0561 | 0.4673 | 0.8362 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0053 | 0.0009 | 0.0293 | 0.0110 | 0.0611 | 0.0250 | 0.0609 | 0.0155 | 0.0819 | 0.0242 | 0.7602 | 0.9234 | 0.0009 | 0.0028 | 0.0090 | 0.0056 | 0.0126 | 0.0306 | 0.0531 | 0.1142 | 0.1178 | 0.1783 | 0.1610 | 0.2256 | 0.1088 | 0.1226 | 0.1403 | 0.1448 | 0.3966 | 0.1755 | 0.0004 | 0.0041 | 0.0137 | 0.0375 | 0.0742 | 0.1187 | 0.0968 | 0.1246 | 0.5300 | 8 | 9 | 11 | 13 | 16 | 27 | 65 | 158 | 326 | 0.1748 | 15.56 | 4.062 | 0.6361 | 38015.9 | 21300000 | 14100000000 | 10500000000000 | 0.4506 | 0.1916 | 0.0704 | 0.0013 | 0.2291 | 0.0191 | 0.3221 | 0.1226 | 0.1709 | 0.2079 | 0.1033 | 0.2447 | 0.0648 | 0.1724 | 0.0207 | 0.1000 | 0.0122 | 0.0771 | 0.0066 | 0.0550 | 0.0003 | 0.0000 | 0.0009 | 0.0005 | 0.0010 | 0.0014 | 0.0081 | 0.0111 | 0.0458 | 0.0427 | 0.0835 | 0.0736 | 0.0487 | 0.0501 | 0.0777 | 0.0719 | 0.7339 | 0.7487 | 0.0002 | 0.0004 | 0.0005 | 0.0002 | 0.0019 | 0.0032 | 0.0112 | 0.0119 | 0.0561 | 0.0571 | 0.0878 | 0.0924 | 0.0591 | 0.0641 | 0.0930 | 0.0948 | 0.6903 | 0.6760 | 0.0002 | 0.0000 | 0.0017 | 0.0096 | 0.0502 | 0.0854 | 0.0527 | 0.0840 | 0.7161 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 981 | 384 | | 5976 | 15063 | 375.2 | 139.04 | 87.22 | 138.43 | 122 | 252 | 332 | 379 | 411 | 436 | 459 | 488 | 529 | 0.0690 | 1040 | 1.006 | 89.27 | 27.02 | 6 | 0.0370 | 221 | 0.0008 | 30.99 | 7.402 | 0.2347 | 160087.0 | 72700000 | 34300000000 | 16600000000000 | 0.3898 | 0.2387 | 0.0000 | 0.0007 | 0.0017 | 0.0002 | 0.0067 | 0.0009 | 0.0168 | 0.0037 | 0.0750 | 0.0273 | 0.1215 | 0.0375 | 0.1056 | 0.0371 | 0.1567 | 0.0526 | 0.5159 | 0.8400 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0010 | 0.0162 | 0.0143 | 0.0270 | 0.0202 | 0.0191 | 0.0149 | 0.0299 | 0.0212 | 0.9067 | 0.9283 | 0.0010 | 0.0079 | 0.0044 | 0.0111 | 0.0092 | 0.0142 | 0.0247 | 0.0190 | 0.0499 | 0.0774 | 0.0727 | 0.0900 | 0.0751 | 0.0979 | 0.0931 | 0.1327 | 0.6699 | 0.5498 | 0.0000 | 0.0000 | 0.0003 | 0.0047 | 0.0261 | 0.0387 | 0.0368 | 0.0506 | 0.8428 | 6 | 9 | 12 | 16 | 25 | 42 | 68 | 128 | 272 | 0.0676 | 12.92 | 4.513 | 0.5910 | 26768.0 | 12200000 | 6560000000 | 3860000000000 | 0.6432 | 0.1082 | 0.0291 | 0.0037 | 0.1315 | 0.0140 | 0.2008 | 0.0494 | 0.1526 | 0.1090 | 0.1345 | 0.1747 | 0.1305 | 0.1850 | 0.0723 | 0.1072 | 0.0773 | 0.1235 | 0.0713 | 0.2335 | 0.0004 | 0.0011 | 0.0020 | 0.0030 | 0.0027 | 0.0032 | 0.0162 | 0.0112 | 0.0605 | 0.0539 | 0.0900 | 0.0723 | 0.0693 | 0.0632 | 0.0924 | 0.0883 | 0.6664 | 0.7038 | 0.0017 | 0.0010 | 0.0017 | 0.0041 | 0.0049 | 0.0073 | 0.0171 | 0.0188 | 0.0713 | 0.0786 | 0.0991 | 0.0958 | 0.0739 | 0.0856 | 0.1026 | 0.1117 | 0.6275 | 0.5969 | 0.0016 | 0.0028 | 0.0041 | 0.0173 | 0.0693 | 0.0929 | 0.0745 | 0.0962 | 0.6412 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 986 | 375 | | 3412 | 6862 | 481.9 | 117.20 | 93.02 | 146.48 | 305 | 387 | 443 | 490 | 520 | 538 | 554 | 572 | 596 | 0.0851 | 584 | 0.932 | 72.01 | 24.21 | 1 | 0.0592 | 202 | 0.0011 | 37.12 | 7.131 | 0.2177 | 245995.0 | 130000000 | 70600000000 | 39000000000000 | 0.3975 | 0.2313 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0023 | 0.0000 | 0.0153 | 0.0006 | 0.0384 | 0.0161 | 0.0685 | 0.0274 | 0.0782 | 0.0187 | 0.1319 | 0.0332 | 0.6645 | 0.9040 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0003 | 0.0179 | 0.0160 | 0.0285 | 0.0249 | 0.0223 | 0.0150 | 0.0347 | 0.0278 | 0.8936 | 0.9159 | 0.0209 | 0.0435 | 0.0104 | 0.0000 | 0.0330 | 0.0000 | 0.0557 | 0.0435 | 0.0783 | 0.3478 | 0.0870 | 0.1739 | 0.0991 | 0.0000 | 0.1113 | 0.3043 | 0.5043 | 0.0870 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0247 | 0.0451 | 0.0400 | 0.0679 | 0.8162 | 10 | 13 | 16 | 21 | 27 | 40 | 68 | 138 | 287 | 0.0426 | 28.93 | 4.699 | 0.5709 | 30108.0 | 15300000 | 9600000000 | 6980000000000 | 0.4972 | 0.1660 | 0.0636 | 0.0056 | 0.1051 | 0.0237 | 0.0954 | 0.0847 | 0.1345 | 0.0790 | 0.1614 | 0.0926 | 0.1809 | 0.1400 | 0.1394 | 0.1264 | 0.0831 | 0.1072 | 0.0367 | 0.3409 | 0.0005 | 0.0013 | 0.0005 | 0.0017 | 0.0036 | 0.0031 | 0.0180 | 0.0144 | 0.0598 | 0.0423 | 0.0721 | 0.0737 | 0.0562 | 0.0471 | 0.0814 | 0.0702 | 0.7079 | 0.7462 | 0.0013 | 0.0000 | 0.0020 | 0.0007 | 0.0007 | 0.0000 | 0.0196 | 0.0156 | 0.0607 | 0.0675 | 0.0881 | 0.0896 | 0.0529 | 0.0490 | 0.0783 | 0.0888 | 0.6965 | 0.6887 | 0.0012 | 0.0012 | 0.0029 | 0.0175 | 0.0544 | 0.0807 | 0.0526 | 0.0807 | 0.7089 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1037 | 548 | | 6893 | 19634 | 196.4 | 53.42 | 59.21 | 59.92 | 132 | 150 | 164 | 177 | 190 | 203 | 219 | 239 | 270 | 0.0562 | 1104 | 1.139 | 106.17 | 38.83 | 1 | 0.0396 | 273 | 0.0009 | 48.97 | 7.272 | 0.1760 | 41433.9 | 9350000 | 2250000000 | 573000000000 | 0.4801 | 0.1819 | 0.0008 | 0.0000 | 0.0027 | 0.0003 | 0.0176 | 0.0008 | 0.0295 | 0.0045 | 0.1140 | 0.0308 | 0.1710 | 0.0578 | 0.1497 | 0.0610 | 0.1702 | 0.0896 | 0.3445 | 0.7552 | 0.0004 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0002 | 0.0060 | 0.0012 | 0.0441 | 0.0158 | 0.0768 | 0.0292 | 0.0676 | 0.0257 | 0.1060 | 0.0467 | 0.6977 | 0.8812 | 0.0027 | 0.0063 | 0.0033 | 0.0110 | 0.0154 | 0.0267 | 0.0642 | 0.0879 | 0.1338 | 0.1586 | 0.1893 | 0.2198 | 0.1097 | 0.1224 | 0.1431 | 0.1429 | 0.3385 | 0.2245 | 0.0019 | 0.0013 | 0.0079 | 0.0282 | 0.0904 | 0.1431 | 0.1028 | 0.1352 | 0.4891 | 11 | 20 | 27 | 36 | 45 | 56 | 68 | 85 | 113 | 0.0115 | 9.46 | 5.188 | 0.4764 | 7095.4 | 1710000 | 681000000 | 349000000000 | 0.5533 | 0.1205 | 0.0095 | 0.0030 | 0.0478 | 0.0089 | 0.1372 | 0.0199 | 0.1794 | 0.0504 | 0.1937 | 0.1192 | 0.1744 | 0.1608 | 0.1277 | 0.1622 | 0.0842 | 0.1835 | 0.0462 | 0.2921 | 0.0014 | 0.0014 | 0.0025 | 0.0030 | 0.0103 | 0.0063 | 0.0254 | 0.0159 | 0.0611 | 0.0437 | 0.0923 | 0.0664 | 0.0846 | 0.0698 | 0.1181 | 0.1017 | 0.6043 | 0.6918 | 0.0040 | 0.0052 | 0.0059 | 0.0136 | 0.0158 | 0.0236 | 0.0370 | 0.0536 | 0.0902 | 0.0983 | 0.1230 | 0.1323 | 0.1097 | 0.1162 | 0.1320 | 0.1328 | 0.4824 | 0.4244 | 0.0026 | 0.0071 | 0.0163 | 0.0301 | 0.0751 | 0.0993 | 0.0984 | 0.1252 | 0.5459 | ||
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 739 | 828 | | 3336 | 10996 | 733.4 | 131.67 | 162.29 | 302.51 | 560 | 619 | 661 | 696 | 729 | 766 | 805 | 848 | 907 | 0.0851 | 936 | 1.020 | 70.01 | 22.36 | 1 | 0.0525 | 175 | 0.0011 | 45.93 | 7.024 | 0.1864 | 555153.0 | 433000000 | 346000000000 | 284000000000000 | 0.4491 | 0.1924 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0070 | 0.0003 | 0.0488 | 0.0168 | 0.1141 | 0.0324 | 0.0930 | 0.0251 | 0.1439 | 0.0321 | 0.5920 | 0.8934 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0003 | 0.0255 | 0.0157 | 0.0541 | 0.0275 | 0.0375 | 0.0151 | 0.0620 | 0.0236 | 0.8185 | 0.9178 | 0.0041 | 0.0000 | 0.0000 | 0.0541 | 0.0269 | 0.1081 | 0.0579 | 0.2432 | 0.1467 | 0.1892 | 0.2004 | 0.2973 | 0.1240 | 0.0270 | 0.1508 | 0.0541 | 0.2893 | 0.0270 | 0.0000 | 0.0025 | 0.0105 | 0.0215 | 0.0732 | 0.0942 | 0.0905 | 0.1046 | 0.6031 | 8 | 10 | 11 | 12 | 14 | 20 | 71 | 262 | 593 | 0.2612 | 53.14 | 3.819 | 0.6522 | 117840.0 | 116000000 | 132000000000 | 164000000000000 | 0.5865 | 0.0859 | 0.1144 | 0.0083 | 0.2779 | 0.0904 | 0.2861 | 0.2629 | 0.1417 | 0.1599 | 0.1063 | 0.1460 | 0.0436 | 0.1252 | 0.0272 | 0.0918 | 0.0027 | 0.0668 | 0.0000 | 0.0487 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0007 | 0.0007 | 0.0093 | 0.0101 | 0.0593 | 0.0520 | 0.1052 | 0.1002 | 0.0576 | 0.0598 | 0.1014 | 0.0881 | 0.6657 | 0.6888 | 0.0000 | 0.0008 | 0.0008 | 0.0013 | 0.0024 | 0.0051 | 0.0154 | 0.0166 | 0.0675 | 0.0696 | 0.1110 | 0.1099 | 0.0667 | 0.0743 | 0.1082 | 0.1002 | 0.6280 | 0.6222 | 0.0000 | 0.0007 | 0.0011 | 0.0136 | 0.0618 | 0.1045 | 0.0674 | 0.0986 | 0.6522 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 582 | 250 | | 4778 | 14966 | 457.7 | 96.53 | 89.22 | 140.57 | 342 | 375 | 399 | 423 | 446 | 472 | 503 | 544 | 595 | 0.0565 | 845 | 1.104 | 103.97 | 26.91 | 1 | 0.0479 | 229 | 0.0010 | 47.20 | 7.130 | 0.1892 | 218847.0 | 109000000 | 56500000000 | 30300000000000 | 0.4000 | 0.2511 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0045 | 0.0004 | 0.0175 | 0.0009 | 0.0684 | 0.0206 | 0.1267 | 0.0402 | 0.1305 | 0.0356 | 0.1626 | 0.0566 | 0.4879 | 0.8457 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0048 | 0.0004 | 0.0342 | 0.0151 | 0.0585 | 0.0274 | 0.0650 | 0.0193 | 0.0849 | 0.0278 | 0.7521 | 0.9101 | 0.0078 | 0.0314 | 0.0045 | 0.0314 | 0.0201 | 0.0419 | 0.0536 | 0.0576 | 0.1095 | 0.2042 | 0.1430 | 0.1937 | 0.1128 | 0.1152 | 0.1296 | 0.1571 | 0.4190 | 0.1675 | 0.0018 | 0.0041 | 0.0115 | 0.0290 | 0.0809 | 0.1241 | 0.0938 | 0.1159 | 0.5389 | 5 | 7 | 8 | 10 | 12 | 21 | 71 | 181 | 309 | 0.1594 | 14.47 | 4.050 | 0.6108 | 27717.5 | 11400000 | 5320000000 | 2730000000000 | 0.4192 | 0.2070 | 0.0600 | 0.0054 | 0.1989 | 0.0109 | 0.2420 | 0.0827 | 0.1839 | 0.1544 | 0.1407 | 0.2452 | 0.0882 | 0.1962 | 0.0563 | 0.0990 | 0.0169 | 0.0990 | 0.0131 | 0.1072 | 0.0002 | 0.0002 | 0.0007 | 0.0002 | 0.0009 | 0.0008 | 0.0083 | 0.0087 | 0.0333 | 0.0322 | 0.0492 | 0.0453 | 0.0395 | 0.0316 | 0.0572 | 0.0465 | 0.8108 | 0.8345 | 0.0000 | 0.0005 | 0.0018 | 0.0005 | 0.0025 | 0.0013 | 0.0079 | 0.0070 | 0.0370 | 0.0436 | 0.0631 | 0.0662 | 0.0484 | 0.0554 | 0.0667 | 0.0759 | 0.7725 | 0.7495 | 0.0000 | 0.0000 | 0.0019 | 0.0086 | 0.0378 | 0.0557 | 0.0431 | 0.0633 | 0.7896 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 872 | 892 | | 3689 | 8762 | 488.5 | 108.21 | 84.63 | 135.98 | 344 | 390 | 427 | 458 | 489 | 518 | 545 | 576 | 623 | 0.0781 | 684 | 1.133 | 118.56 | 47.04 | 1 | 0.0848 | 313 | 0.0006 | 83.19 | 7.600 | 0.1213 | 250362.0 | 134000000 | 74800000000 | 43400000000000 | 0.4340 | 0.2055 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0003 | 0.0153 | 0.0026 | 0.0610 | 0.0249 | 0.1194 | 0.0435 | 0.1225 | 0.0384 | 0.1500 | 0.0501 | 0.5305 | 0.8402 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0003 | 0.0075 | 0.0017 | 0.0282 | 0.0215 | 0.0411 | 0.0345 | 0.0380 | 0.0246 | 0.0598 | 0.0328 | 0.8247 | 0.8846 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0231 | 0.0000 | 0.0738 | 0.0000 | 0.1323 | 0.0000 | 0.1877 | 0.0000 | 0.1092 | 0.0000 | 0.1154 | 0.0000 | 0.3569 | 0.0000 | 0.0000 | 0.0011 | 0.0032 | 0.0151 | 0.0572 | 0.1068 | 0.0766 | 0.1176 | 0.6224 | 14 | 16 | 19 | 24 | 34 | 51 | 71 | 100 | 208 | 0.0576 | 11.33 | 4.133 | 0.6484 | 25648.9 | 14400000 | 10400000000 | 8570000000000 | 0.5629 | 0.1030 | 0.0175 | 0.0040 | 0.0903 | 0.0070 | 0.1233 | 0.0663 | 0.1155 | 0.0713 | 0.1291 | 0.1216 | 0.1107 | 0.1266 | 0.1097 | 0.1077 | 0.1175 | 0.1171 | 0.1864 | 0.3784 | 0.0014 | 0.0017 | 0.0025 | 0.0028 | 0.0076 | 0.0083 | 0.0245 | 0.0185 | 0.0736 | 0.0578 | 0.0848 | 0.0797 | 0.0704 | 0.0606 | 0.1050 | 0.0857 | 0.6301 | 0.6850 | 0.0011 | 0.0007 | 0.0011 | 0.0027 | 0.0080 | 0.0066 | 0.0218 | 0.0199 | 0.0856 | 0.0922 | 0.1287 | 0.1293 | 0.0666 | 0.0663 | 0.1034 | 0.1015 | 0.5836 | 0.5809 | 0.0042 | 0.0056 | 0.0075 | 0.0258 | 0.0714 | 0.1104 | 0.0770 | 0.0968 | 0.6012 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1074 | 329 | | 10716 | 23313 | 347.7 | 91.75 | 73.56 | 114.94 | 242 | 269 | 292 | 314 | 335 | 358 | 384 | 417 | 474 | 0.0592 | 1380 | 0.979 | 123.69 | 46.10 | 1 | 0.0314 | 336 | 0.0009 | 44.10 | 7.309 | 0.1906 | 129299.0 | 51400000 | 21900000000 | 9900000000000 | 0.4246 | 0.2290 | 0.0002 | 0.0000 | 0.0013 | 0.0000 | 0.0081 | 0.0003 | 0.0209 | 0.0023 | 0.0739 | 0.0236 | 0.1547 | 0.0469 | 0.1487 | 0.0470 | 0.1829 | 0.0798 | 0.4092 | 0.8000 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0001 | 0.0067 | 0.0011 | 0.0320 | 0.0128 | 0.0693 | 0.0240 | 0.0655 | 0.0222 | 0.0943 | 0.0426 | 0.7287 | 0.8973 | 0.0038 | 0.0033 | 0.0108 | 0.0043 | 0.0169 | 0.0174 | 0.0606 | 0.0587 | 0.0983 | 0.1293 | 0.1396 | 0.1772 | 0.0973 | 0.1283 | 0.1189 | 0.1533 | 0.4537 | 0.3283 | 0.0011 | 0.0027 | 0.0078 | 0.0287 | 0.0782 | 0.1249 | 0.0938 | 0.1276 | 0.5352 | 5 | 6 | 8 | 9 | 13 | 34 | 72 | 133 | 226 | 0.0834 | 10.03 | 3.982 | 0.5196 | 18622.6 | 7300000 | 3800000000 | 2450000000000 | 0.4789 | 0.1814 | 0.0998 | 0.0031 | 0.2338 | 0.0435 | 0.2680 | 0.1682 | 0.1369 | 0.1634 | 0.1119 | 0.1864 | 0.0720 | 0.1590 | 0.0371 | 0.0956 | 0.0306 | 0.0815 | 0.0100 | 0.0993 | 0.0004 | 0.0001 | 0.0003 | 0.0006 | 0.0013 | 0.0018 | 0.0095 | 0.0100 | 0.0610 | 0.0508 | 0.0917 | 0.0745 | 0.0604 | 0.0548 | 0.1046 | 0.0852 | 0.6708 | 0.7222 | 0.0002 | 0.0004 | 0.0018 | 0.0009 | 0.0024 | 0.0034 | 0.0180 | 0.0181 | 0.0720 | 0.0856 | 0.1220 | 0.1315 | 0.0802 | 0.0846 | 0.1175 | 0.1264 | 0.5860 | 0.5492 | 0.0001 | 0.0003 | 0.0026 | 0.0135 | 0.0658 | 0.1063 | 0.0699 | 0.1141 | 0.6274 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 923 | 124 | | 725 | 2122 | 76.0 | 19.18 | 87.85 | 150.35 | 55 | 62 | 66 | 70 | 74 | 78 | 82 | 89 | 98 | 0.1555 | 330 | 1.062 | 83.67 | 27.73 | 1 | 0.3007 | 218 | 0.0059 | 12.27 | 5.382 | 0.3021 | 6143.7 | 529049 | 48700000 | 4800000000 | 0.4598 | 0.1774 | 0.0021 | 0.0000 | 0.0105 | 0.0000 | 0.0316 | 0.0062 | 0.0547 | 0.0170 | 0.1116 | 0.0602 | 0.1495 | 0.0802 | 0.1558 | 0.0725 | 0.1811 | 0.1065 | 0.3032 | 0.6574 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0100 | 0.0014 | 0.0067 | 0.0029 | 0.0585 | 0.0432 | 0.1137 | 0.0748 | 0.0870 | 0.0489 | 0.1421 | 0.0691 | 0.5803 | 0.7597 | 0.0081 | 0.0213 | 0.0488 | 0.0000 | 0.0407 | 0.0638 | 0.0894 | 0.1489 | 0.2602 | 0.2340 | 0.1057 | 0.2340 | 0.1545 | 0.0638 | 0.1463 | 0.0851 | 0.1463 | 0.1489 | 0.0000 | 0.0030 | 0.0302 | 0.0604 | 0.1329 | 0.1813 | 0.1390 | 0.1601 | 0.2931 | 14 | 17 | 20 | 25 | 38 | 53 | 73 | 106 | 191 | 0.0472 | 42.92 | 4.329 | 0.5495 | 30310.8 | 21700000 | 20800000000 | 23000000000000 | 0.5356 | 0.1304 | 0.0400 | 0.0000 | 0.1778 | 0.0200 | 0.1689 | 0.0798 | 0.2267 | 0.1098 | 0.1289 | 0.1377 | 0.1333 | 0.1896 | 0.0978 | 0.1337 | 0.0178 | 0.1018 | 0.0089 | 0.2275 | 0.0015 | 0.0000 | 0.0122 | 0.0000 | 0.0198 | 0.0141 | 0.0517 | 0.0387 | 0.0836 | 0.0810 | 0.1049 | 0.1244 | 0.1094 | 0.0845 | 0.1261 | 0.1315 | 0.4909 | 0.5258 | 0.0000 | 0.0028 | 0.0139 | 0.0057 | 0.0254 | 0.0256 | 0.0647 | 0.0427 | 0.1062 | 0.1225 | 0.1201 | 0.1595 | 0.1178 | 0.0798 | 0.1293 | 0.1681 | 0.4226 | 0.3932 | 0.0019 | 0.0130 | 0.0093 | 0.0484 | 0.1043 | 0.1229 | 0.0987 | 0.1378 | 0.4637 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 949 | 628 | | 5444 | 5921 | 503.2 | 113.35 | 118.69 | 220.33 | 340 | 443 | 485 | 510 | 528 | 546 | 564 | 585 | 614 | 0.1099 | 651 | 1.294 | 20.22 | 8.60 | 1 | 0.0103 | 56 | 0.0029 | 17.80 | 6.312 | 0.3065 | 266047.0 | 145000000 | 80700000000 | 45600000000000 | 0.4084 | 0.2255 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0074 | 0.0008 | 0.0372 | 0.0133 | 0.0597 | 0.0230 | 0.0638 | 0.0153 | 0.1089 | 0.0266 | 0.7193 | 0.9208 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0004 | 0.0158 | 0.0130 | 0.0270 | 0.0200 | 0.0203 | 0.0120 | 0.0363 | 0.0200 | 0.8999 | 0.9346 | 0.0097 | 0.0000 | 0.0110 | 0.0789 | 0.0331 | 0.1579 | 0.0607 | 0.0789 | 0.1062 | 0.1842 | 0.1407 | 0.1053 | 0.1407 | 0.0789 | 0.1434 | 0.2105 | 0.3545 | 0.1053 | 0.0000 | 0.0009 | 0.0035 | 0.0087 | 0.0363 | 0.0603 | 0.0609 | 0.0873 | 0.7421 | 7 | 10 | 14 | 19 | 25 | 37 | 74 | 153 | 375 | 0.0775 | 22.34 | 4.056 | 0.5583 | 62626.7 | 51300000 | 50500000000 | 55700000000000 | 0.5274 | 0.1314 | 0.0603 | 0.0015 | 0.2190 | 0.0164 | 0.3175 | 0.0848 | 0.1429 | 0.1711 | 0.1524 | 0.2321 | 0.0603 | 0.2292 | 0.0222 | 0.1295 | 0.0159 | 0.0744 | 0.0095 | 0.0610 | 0.0013 | 0.0006 | 0.0051 | 0.0011 | 0.0019 | 0.0033 | 0.0103 | 0.0094 | 0.0994 | 0.0833 | 0.1186 | 0.1127 | 0.0962 | 0.0944 | 0.1237 | 0.1133 | 0.5436 | 0.5819 | 0.0000 | 0.0009 | 0.0016 | 0.0009 | 0.0072 | 0.0071 | 0.0177 | 0.0301 | 0.1157 | 0.1125 | 0.1301 | 0.1364 | 0.1028 | 0.0912 | 0.1205 | 0.1355 | 0.5044 | 0.4854 | 0.0007 | 0.0007 | 0.0036 | 0.0144 | 0.1114 | 0.1222 | 0.0978 | 0.1258 | 0.5234 |