High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1197 | 726 | | 3699 | 9192 | 137.4 | 44.39 | 37.17 | 36.11 | 98 | 107 | 113 | 119 | 127 | 135 | 146 | 160 | 187 | 0.0926 | 851 | 1.180 | 107.28 | 41.01 | 1 | 0.0746 | 276 | 0.0024 | 30.51 | 6.416 | 0.2449 | 20843.7 | 3610000 | 733000000 | 177000000000 | 0.4112 | 0.2401 | 0.0009 | 0.0003 | 0.0037 | 0.0006 | 0.0107 | 0.0009 | 0.0409 | 0.0027 | 0.0991 | 0.0285 | 0.1647 | 0.0612 | 0.1629 | 0.0558 | 0.2010 | 0.0876 | 0.3160 | 0.7623 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0050 | 0.0000 | 0.0210 | 0.0014 | 0.0522 | 0.0177 | 0.0878 | 0.0343 | 0.0906 | 0.0296 | 0.1372 | 0.0500 | 0.6048 | 0.8670 | 0.0060 | 0.0031 | 0.0105 | 0.0031 | 0.0180 | 0.0251 | 0.0481 | 0.0721 | 0.1008 | 0.1755 | 0.1474 | 0.1850 | 0.1158 | 0.1129 | 0.1549 | 0.1348 | 0.3985 | 0.2884 | 0.0049 | 0.0084 | 0.0182 | 0.0477 | 0.0869 | 0.1170 | 0.0953 | 0.0988 | 0.5228 | 9 | 13 | 17 | 21 | 25 | 32 | 40 | 53 | 80 | 0.0260 | 5.48 | 4.415 | 0.5610 | 2685.3 | 330423 | 59700000 | 14100000000 | 0.5938 | 0.1120 | 0.0235 | 0.0088 | 0.0780 | 0.0186 | 0.1751 | 0.0368 | 0.2151 | 0.0862 | 0.2240 | 0.1372 | 0.1421 | 0.1696 | 0.0882 | 0.1863 | 0.0406 | 0.1875 | 0.0133 | 0.1690 | 0.0060 | 0.0053 | 0.0070 | 0.0086 | 0.0141 | 0.0129 | 0.0319 | 0.0244 | 0.0718 | 0.0561 | 0.1115 | 0.0821 | 0.1027 | 0.0929 | 0.1364 | 0.1305 | 0.5185 | 0.5871 | 0.0033 | 0.0083 | 0.0129 | 0.0119 | 0.0220 | 0.0217 | 0.0407 | 0.0620 | 0.1073 | 0.1168 | 0.1401 | 0.1302 | 0.1052 | 0.1111 | 0.1393 | 0.1292 | 0.4291 | 0.4088 | 0.0032 | 0.0106 | 0.0122 | 0.0448 | 0.0860 | 0.1246 | 0.1159 | 0.1259 | 0.4767 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 538 | 522 | | 10143 | 24967 | 137.2 | 45.41 | 180.80 | 230.55 | 91 | 101 | 110 | 118 | 127 | 137 | 150 | 167 | 198 | 0.0470 | 1173 | 0.400 | 194.49 | 33.54 | 5 | 0.0550 | 558 | 0.0019 | 26.27 | 6.724 | 0.2500 | 20883.8 | 3560000 | 679000000 | 145000000000 | 0.4664 | 0.1883 | 0.0012 | 0.0001 | 0.0036 | 0.0001 | 0.0091 | 0.0012 | 0.0383 | 0.0057 | 0.1113 | 0.0305 | 0.1764 | 0.0645 | 0.1603 | 0.0659 | 0.1744 | 0.0958 | 0.3255 | 0.7361 | 0.0007 | 0.0001 | 0.0021 | 0.0001 | 0.0034 | 0.0007 | 0.0142 | 0.0028 | 0.0411 | 0.0161 | 0.0774 | 0.0311 | 0.0693 | 0.0286 | 0.0908 | 0.0446 | 0.7011 | 0.8759 | 0.0032 | 0.0009 | 0.0055 | 0.0026 | 0.0120 | 0.0205 | 0.0443 | 0.0759 | 0.1061 | 0.1253 | 0.1513 | 0.1748 | 0.1070 | 0.1228 | 0.1402 | 0.1313 | 0.4304 | 0.3461 | 0.0022 | 0.0049 | 0.0080 | 0.0279 | 0.0670 | 0.1061 | 0.0989 | 0.1234 | 0.5616 | 11 | 13 | 17 | 26 | 61 | 137 | 226 | 346 | 527 | 0.0541 | 38.24 | 5.495 | 0.4994 | 85842.1 | 54700000 | 40900000000 | 34200000000000 | 0.5806 | 0.1163 | 0.0514 | 0.0037 | 0.1686 | 0.0204 | 0.2152 | 0.1049 | 0.1551 | 0.1368 | 0.1378 | 0.1772 | 0.1287 | 0.1802 | 0.0730 | 0.1206 | 0.0476 | 0.1111 | 0.0226 | 0.1450 | 0.0004 | 0.0003 | 0.0008 | 0.0002 | 0.0017 | 0.0011 | 0.0086 | 0.0061 | 0.0487 | 0.0419 | 0.0930 | 0.0753 | 0.0691 | 0.0562 | 0.0965 | 0.0845 | 0.6812 | 0.7344 | 0.0005 | 0.0003 | 0.0014 | 0.0013 | 0.0031 | 0.0041 | 0.0161 | 0.0199 | 0.0661 | 0.0733 | 0.1165 | 0.1280 | 0.0805 | 0.0882 | 0.1160 | 0.1179 | 0.5998 | 0.5670 | 0.0002 | 0.0007 | 0.0022 | 0.0128 | 0.0574 | 0.1049 | 0.0737 | 0.1099 | 0.6383 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1049 | 270 | | 3875 | 7952 | 133.1 | 35.91 | 157.83 | 125.74 | 94 | 104 | 113 | 121 | 128 | 136 | 145 | 157 | 179 | 0.0832 | 662 | 0.854 | 78.82 | 25.55 | 2 | 0.0565 | 219 | 0.0020 | 26.25 | 6.494 | 0.2455 | 18997.6 | 2930000 | 490000000 | 89600000000 | 0.4209 | 0.2213 | 0.0000 | 0.0003 | 0.0004 | 0.0000 | 0.0074 | 0.0003 | 0.0302 | 0.0020 | 0.0944 | 0.0294 | 0.1627 | 0.0582 | 0.1605 | 0.0616 | 0.1828 | 0.0913 | 0.3616 | 0.7570 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0030 | 0.0000 | 0.0097 | 0.0003 | 0.0462 | 0.0196 | 0.0716 | 0.0346 | 0.0726 | 0.0291 | 0.1044 | 0.0471 | 0.6921 | 0.8694 | 0.0086 | 0.0097 | 0.0143 | 0.0065 | 0.0399 | 0.0259 | 0.0799 | 0.1003 | 0.1241 | 0.1586 | 0.1526 | 0.1715 | 0.0984 | 0.1100 | 0.1184 | 0.1683 | 0.3638 | 0.2492 | 0.0024 | 0.0083 | 0.0166 | 0.0391 | 0.1073 | 0.1375 | 0.1203 | 0.1316 | 0.4369 | 26 | 44 | 68 | 98 | 128 | 163 | 203 | 251 | 336 | 0.0035 | 41.32 | 6.588 | 0.3220 | 40720.6 | 13800000 | 5550000000 | 2540000000000 | 0.4558 | 0.2138 | 0.0196 | 0.0022 | 0.0713 | 0.0072 | 0.1578 | 0.0421 | 0.1767 | 0.0623 | 0.2000 | 0.1326 | 0.1804 | 0.1870 | 0.1084 | 0.1581 | 0.0531 | 0.1675 | 0.0327 | 0.2410 | 0.0012 | 0.0000 | 0.0015 | 0.0021 | 0.0055 | 0.0037 | 0.0159 | 0.0118 | 0.0585 | 0.0468 | 0.0938 | 0.0773 | 0.0774 | 0.0664 | 0.1074 | 0.0880 | 0.6388 | 0.7040 | 0.0008 | 0.0034 | 0.0053 | 0.0087 | 0.0120 | 0.0135 | 0.0361 | 0.0429 | 0.0847 | 0.1118 | 0.1295 | 0.1301 | 0.1043 | 0.1186 | 0.1401 | 0.1533 | 0.4872 | 0.4178 | 0.0006 | 0.0033 | 0.0108 | 0.0222 | 0.0752 | 0.1049 | 0.0869 | 0.1254 | 0.5707 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1235 | 928 | | 3908 | 866 | 131.6 | 35.52 | 83.99 | 75.24 | 92 | 104 | 113 | 120 | 128 | 134 | 143 | 154 | 171 | 0.5855 | 507 | 1.261 | 98.62 | 31.32 | 1 | 0.0581 | 227 | 0.0023 | 24.71 | 6.369 | 0.2431 | 18576.3 | 2850000 | 480000000 | 90700000000 | 0.4962 | 0.1800 | 0.0025 | 0.0000 | 0.0025 | 0.0003 | 0.0091 | 0.0020 | 0.0313 | 0.0045 | 0.0844 | 0.0247 | 0.1671 | 0.0656 | 0.1560 | 0.0617 | 0.1844 | 0.1041 | 0.3627 | 0.7372 | 0.0000 | 0.0000 | 0.0013 | 0.0003 | 0.0026 | 0.0016 | 0.0107 | 0.0024 | 0.0488 | 0.0200 | 0.0837 | 0.0431 | 0.0755 | 0.0318 | 0.1153 | 0.0568 | 0.6620 | 0.8442 | 0.0109 | 0.0207 | 0.0125 | 0.0290 | 0.0498 | 0.0290 | 0.0888 | 0.1079 | 0.1495 | 0.1992 | 0.1947 | 0.1826 | 0.1137 | 0.0747 | 0.1340 | 0.1452 | 0.2461 | 0.2116 | 0.0012 | 0.0075 | 0.0184 | 0.0519 | 0.1308 | 0.1360 | 0.1314 | 0.1527 | 0.3700 | 16 | 24 | 36 | 50 | 62 | 79 | 105 | 130 | 176 | 0.0070 | 32.32 | 5.471 | 0.3545 | 12708.8 | 3020000 | 1050000000 | 473000000000 | 0.5943 | 0.0759 | 0.0880 | 0.0099 | 0.2240 | 0.0627 | 0.2160 | 0.0924 | 0.2480 | 0.1881 | 0.1600 | 0.2277 | 0.0560 | 0.2376 | 0.0080 | 0.0792 | 0.0000 | 0.0528 | 0.0000 | 0.0495 | 0.0150 | 0.0019 | 0.0200 | 0.0174 | 0.0324 | 0.0174 | 0.0549 | 0.0581 | 0.2893 | 0.2364 | 0.3566 | 0.3682 | 0.1322 | 0.1492 | 0.0574 | 0.0717 | 0.0424 | 0.0795 | 0.0072 | 0.0047 | 0.0217 | 0.0235 | 0.0580 | 0.0798 | 0.1051 | 0.1221 | 0.2754 | 0.2864 | 0.3370 | 0.3146 | 0.1123 | 0.0986 | 0.0507 | 0.0376 | 0.0326 | 0.0329 | 0.0151 | 0.0151 | 0.0272 | 0.1057 | 0.2779 | 0.3595 | 0.1178 | 0.0453 | 0.0363 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1101 | 742 | | 4651 | 3841 | 130.8 | 24.62 | 205.76 | 139.04 | 103 | 111 | 116 | 122 | 128 | 133 | 140 | 148 | 161 | 0.1854 | 712 | 1.111 | 92.85 | 30.41 | 1 | 0.0495 | 230 | 0.0036 | 13.07 | 5.941 | 0.2993 | 17710.9 | 2490000 | 365000000 | 56000000000 | 0.4257 | 0.2249 | 0.0014 | 0.0000 | 0.0040 | 0.0000 | 0.0071 | 0.0000 | 0.0190 | 0.0025 | 0.0451 | 0.0167 | 0.0984 | 0.0362 | 0.1083 | 0.0292 | 0.1549 | 0.0442 | 0.5618 | 0.8712 | 0.0012 | 0.0000 | 0.0029 | 0.0000 | 0.0054 | 0.0000 | 0.0103 | 0.0017 | 0.0254 | 0.0129 | 0.0548 | 0.0241 | 0.0523 | 0.0146 | 0.0807 | 0.0226 | 0.7669 | 0.9241 | 0.0071 | 0.0059 | 0.0196 | 0.0294 | 0.0445 | 0.0471 | 0.0943 | 0.0824 | 0.1423 | 0.1765 | 0.1637 | 0.2176 | 0.1121 | 0.0706 | 0.1174 | 0.1647 | 0.2989 | 0.2059 | 0.0044 | 0.0083 | 0.0151 | 0.0432 | 0.0763 | 0.1122 | 0.1102 | 0.1336 | 0.4968 | 59 | 93 | 118 | 141 | 168 | 200 | 248 | 312 | 412 | 0.0015 | 56.43 | 6.903 | 0.2245 | 61663.9 | 23700000 | 10900000000 | 5660000000000 | 0.4849 | 0.1602 | 0.0169 | 0.0036 | 0.0784 | 0.0118 | 0.1858 | 0.0391 | 0.1701 | 0.0751 | 0.1725 | 0.1438 | 0.1556 | 0.1746 | 0.0941 | 0.1473 | 0.0760 | 0.1444 | 0.0507 | 0.2604 | 0.0020 | 0.0019 | 0.0040 | 0.0035 | 0.0106 | 0.0089 | 0.0323 | 0.0216 | 0.0751 | 0.0589 | 0.1280 | 0.0971 | 0.1154 | 0.0890 | 0.1260 | 0.1125 | 0.5066 | 0.6067 | 0.0017 | 0.0044 | 0.0121 | 0.0077 | 0.0113 | 0.0221 | 0.0459 | 0.0464 | 0.1013 | 0.1380 | 0.1636 | 0.1435 | 0.1022 | 0.1280 | 0.1411 | 0.1523 | 0.4208 | 0.3576 | 0.0020 | 0.0101 | 0.0181 | 0.0322 | 0.0938 | 0.1434 | 0.1139 | 0.1273 | 0.4591 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 680 | 551 | | 5987 | 6093 | 134.6 | 38.08 | 176.05 | 235.22 | 92 | 104 | 113 | 122 | 129 | 138 | 148 | 161 | 182 | 0.1188 | 724 | 1.000 | 95.60 | 29.27 | 1 | 0.0403 | 241 | 0.0020 | 24.09 | 6.532 | 0.2581 | 19556.5 | 3090000 | 540000000 | 105000000000 | 0.4491 | 0.2026 | 0.0006 | 0.0000 | 0.0035 | 0.0004 | 0.0088 | 0.0006 | 0.0253 | 0.0021 | 0.0823 | 0.0225 | 0.1531 | 0.0497 | 0.1611 | 0.0584 | 0.1743 | 0.0871 | 0.3909 | 0.7792 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0031 | 0.0000 | 0.0090 | 0.0005 | 0.0374 | 0.0132 | 0.0593 | 0.0258 | 0.0654 | 0.0231 | 0.0842 | 0.0390 | 0.7408 | 0.8984 | 0.0009 | 0.0104 | 0.0128 | 0.0084 | 0.0239 | 0.0251 | 0.0632 | 0.0898 | 0.1376 | 0.1962 | 0.1709 | 0.1649 | 0.1043 | 0.1211 | 0.1564 | 0.1608 | 0.3299 | 0.2234 | 0.0023 | 0.0023 | 0.0095 | 0.0338 | 0.0834 | 0.1244 | 0.1085 | 0.1301 | 0.5059 | 10 | 11 | 13 | 16 | 34 | 115 | 229 | 352 | 553 | 0.1116 | 42.16 | 4.818 | 0.5374 | 86309.7 | 54700000 | 39600000000 | 31400000000000 | 0.5384 | 0.1532 | 0.0884 | 0.0052 | 0.2601 | 0.0551 | 0.2652 | 0.1627 | 0.1288 | 0.1890 | 0.0833 | 0.2008 | 0.0758 | 0.1444 | 0.0581 | 0.0866 | 0.0227 | 0.0735 | 0.0177 | 0.0827 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0020 | 0.0121 | 0.0068 | 0.0484 | 0.0419 | 0.0963 | 0.0971 | 0.0652 | 0.0532 | 0.0963 | 0.0789 | 0.6799 | 0.7201 | 0.0000 | 0.0006 | 0.0016 | 0.0017 | 0.0021 | 0.0058 | 0.0172 | 0.0221 | 0.0667 | 0.0813 | 0.1199 | 0.1371 | 0.0896 | 0.0936 | 0.1214 | 0.1174 | 0.5816 | 0.5404 | 0.0000 | 0.0014 | 0.0023 | 0.0136 | 0.0567 | 0.1068 | 0.0829 | 0.1036 | 0.6326 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 804 | 192 | | 9922 | 14775 | 134.6 | 40.27 | 276.51 | 259.87 | 90 | 102 | 111 | 120 | 129 | 139 | 151 | 165 | 185 | 0.0923 | 1363 | 0.678 | 210.00 | 48.17 | 5 | 0.0555 | 551 | 0.0016 | 25.40 | 6.776 | 0.2333 | 19732.5 | 3150000 | 551000000 | 105000000000 | 0.4834 | 0.1711 | 0.0002 | 0.0002 | 0.0017 | 0.0006 | 0.0103 | 0.0011 | 0.0422 | 0.0040 | 0.1105 | 0.0312 | 0.1807 | 0.0675 | 0.1790 | 0.0732 | 0.1797 | 0.1114 | 0.2958 | 0.7108 | 0.0000 | 0.0001 | 0.0008 | 0.0005 | 0.0029 | 0.0007 | 0.0109 | 0.0020 | 0.0409 | 0.0198 | 0.0753 | 0.0371 | 0.0711 | 0.0313 | 0.0968 | 0.0504 | 0.7013 | 0.8580 | 0.0027 | 0.0123 | 0.0096 | 0.0212 | 0.0183 | 0.0368 | 0.0636 | 0.0982 | 0.1208 | 0.1618 | 0.1707 | 0.1696 | 0.1304 | 0.1027 | 0.1405 | 0.1395 | 0.3432 | 0.2578 | 0.0009 | 0.0023 | 0.0100 | 0.0275 | 0.0776 | 0.1327 | 0.1116 | 0.1316 | 0.5059 | 27 | 54 | 105 | 157 | 206 | 265 | 334 | 441 | 628 | 0.0057 | 57.11 | 6.881 | 0.3026 | 143987.0 | 105000000 | 93700000000 | 95000000000000 | 0.6013 | 0.0968 | 0.0216 | 0.0014 | 0.0960 | 0.0083 | 0.1877 | 0.0540 | 0.1629 | 0.0789 | 0.1693 | 0.1505 | 0.1733 | 0.1848 | 0.0968 | 0.1576 | 0.0464 | 0.1582 | 0.0460 | 0.2061 | 0.0006 | 0.0002 | 0.0016 | 0.0005 | 0.0059 | 0.0036 | 0.0231 | 0.0129 | 0.0764 | 0.0640 | 0.1265 | 0.1009 | 0.0993 | 0.0832 | 0.1089 | 0.1172 | 0.5577 | 0.6175 | 0.0025 | 0.0011 | 0.0056 | 0.0083 | 0.0181 | 0.0174 | 0.0350 | 0.0365 | 0.0934 | 0.0970 | 0.1313 | 0.1352 | 0.0834 | 0.0918 | 0.1084 | 0.1086 | 0.5223 | 0.5041 | 0.0012 | 0.0041 | 0.0118 | 0.0325 | 0.0905 | 0.1330 | 0.0907 | 0.1109 | 0.5253 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 917 | 765 | | 4787 | 6025 | 134.0 | 29.36 | 199.47 | 144.31 | 101 | 111 | 117 | 124 | 130 | 137 | 145 | 154 | 168 | 0.1200 | 723 | 1.159 | 112.49 | 39.01 | 1 | 0.0570 | 273 | 0.0026 | 20.01 | 6.253 | 0.2547 | 18810.6 | 2780000 | 434000000 | 72000000000 | 0.4427 | 0.2093 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0064 | 0.0013 | 0.0155 | 0.0016 | 0.0709 | 0.0202 | 0.1267 | 0.0377 | 0.1506 | 0.0388 | 0.1815 | 0.0566 | 0.4467 | 0.8438 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0073 | 0.0004 | 0.0405 | 0.0149 | 0.0653 | 0.0246 | 0.0710 | 0.0181 | 0.0965 | 0.0305 | 0.7169 | 0.9114 | 0.0043 | 0.0000 | 0.0157 | 0.0082 | 0.0443 | 0.0286 | 0.0944 | 0.1224 | 0.1688 | 0.1510 | 0.1574 | 0.2041 | 0.0987 | 0.1102 | 0.1273 | 0.1224 | 0.2890 | 0.2531 | 0.0018 | 0.0042 | 0.0125 | 0.0365 | 0.0983 | 0.1347 | 0.1117 | 0.1440 | 0.4564 | 44 | 68 | 100 | 134 | 171 | 211 | 256 | 309 | 392 | 0.0015 | 70.67 | 7.066 | 0.2195 | 60610.6 | 23900000 | 11300000000 | 6160000000000 | 0.5305 | 0.1272 | 0.0202 | 0.0004 | 0.0960 | 0.0047 | 0.2098 | 0.0436 | 0.2030 | 0.0781 | 0.1955 | 0.1872 | 0.1348 | 0.1919 | 0.0851 | 0.1725 | 0.0447 | 0.1552 | 0.0110 | 0.1665 | 0.0006 | 0.0003 | 0.0009 | 0.0005 | 0.0019 | 0.0026 | 0.0206 | 0.0127 | 0.0768 | 0.0560 | 0.1070 | 0.0915 | 0.0989 | 0.0710 | 0.1385 | 0.1099 | 0.5548 | 0.6556 | 0.0015 | 0.0032 | 0.0064 | 0.0097 | 0.0124 | 0.0175 | 0.0500 | 0.0662 | 0.1199 | 0.1364 | 0.1640 | 0.1857 | 0.1189 | 0.1422 | 0.1690 | 0.1513 | 0.3578 | 0.2877 | 0.0008 | 0.0008 | 0.0077 | 0.0291 | 0.0926 | 0.1403 | 0.1170 | 0.1592 | 0.4525 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 921 | 565 | | 4515 | 12772 | 136.3 | 38.62 | 135.27 | 164.66 | 95 | 105 | 113 | 121 | 130 | 139 | 150 | 162 | 185 | 0.0755 | 964 | 1.187 | 118.21 | 44.41 | 1 | 0.0669 | 302 | 0.0020 | 26.20 | 6.545 | 0.2402 | 20065.9 | 3220000 | 568000000 | 111000000000 | 0.4520 | 0.1988 | 0.0008 | 0.0000 | 0.0063 | 0.0002 | 0.0079 | 0.0015 | 0.0359 | 0.0057 | 0.1031 | 0.0269 | 0.1647 | 0.0507 | 0.1686 | 0.0672 | 0.1675 | 0.0961 | 0.3452 | 0.7517 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0038 | 0.0000 | 0.0148 | 0.0023 | 0.0440 | 0.0169 | 0.0750 | 0.0289 | 0.0735 | 0.0321 | 0.1004 | 0.0456 | 0.6856 | 0.8742 | 0.0058 | 0.0106 | 0.0023 | 0.0079 | 0.0257 | 0.0475 | 0.0690 | 0.1055 | 0.1415 | 0.1583 | 0.1825 | 0.1900 | 0.1158 | 0.1161 | 0.1485 | 0.1451 | 0.3088 | 0.2190 | 0.0010 | 0.0041 | 0.0066 | 0.0259 | 0.0984 | 0.1324 | 0.1014 | 0.1460 | 0.4843 | 15 | 25 | 38 | 52 | 69 | 95 | 139 | 214 | 357 | 0.0059 | 46.41 | 6.387 | 0.3599 | 45409.4 | 23600000 | 15300000000 | 11300000000000 | 0.5555 | 0.1162 | 0.0282 | 0.0014 | 0.1229 | 0.0134 | 0.1832 | 0.0569 | 0.1691 | 0.0999 | 0.1660 | 0.1578 | 0.1644 | 0.1942 | 0.0854 | 0.1469 | 0.0517 | 0.1487 | 0.0290 | 0.1808 | 0.0009 | 0.0005 | 0.0011 | 0.0026 | 0.0036 | 0.0047 | 0.0189 | 0.0160 | 0.0560 | 0.0476 | 0.0910 | 0.0845 | 0.0674 | 0.0653 | 0.0964 | 0.0962 | 0.6647 | 0.6826 | 0.0003 | 0.0003 | 0.0015 | 0.0010 | 0.0050 | 0.0096 | 0.0207 | 0.0244 | 0.0645 | 0.0753 | 0.1112 | 0.1073 | 0.0721 | 0.0815 | 0.1076 | 0.1100 | 0.6171 | 0.5904 | 0.0013 | 0.0013 | 0.0066 | 0.0151 | 0.0602 | 0.0983 | 0.0748 | 0.0985 | 0.6440 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 640 | 505 | | 7321 | 15664 | 132.9 | 24.36 | 203.28 | 114.00 | 103 | 113 | 120 | 126 | 131 | 137 | 144 | 152 | 164 | 0.0602 | 943 | 0.886 | 94.20 | 24.52 | 1 | 0.0328 | 240 | 0.0034 | 11.56 | 6.014 | 0.3124 | 18256.5 | 2590000 | 379000000 | 57200000000 | 0.4249 | 0.2269 | 0.0000 | 0.0001 | 0.0000 | 0.0000 | 0.0031 | 0.0001 | 0.0107 | 0.0008 | 0.0451 | 0.0126 | 0.0959 | 0.0291 | 0.1106 | 0.0302 | 0.1519 | 0.0455 | 0.5827 | 0.8815 | 0.0000 | 0.0001 | 0.0000 | 0.0000 | 0.0013 | 0.0001 | 0.0041 | 0.0006 | 0.0213 | 0.0113 | 0.0421 | 0.0206 | 0.0458 | 0.0151 | 0.0696 | 0.0214 | 0.8160 | 0.9308 | 0.0083 | 0.0311 | 0.0156 | 0.0497 | 0.0353 | 0.0807 | 0.1048 | 0.1491 | 0.1566 | 0.2609 | 0.1940 | 0.1677 | 0.1193 | 0.0621 | 0.1421 | 0.1429 | 0.2241 | 0.0559 | 0.0026 | 0.0048 | 0.0145 | 0.0318 | 0.0705 | 0.1166 | 0.1066 | 0.1362 | 0.5163 | 66 | 100 | 130 | 159 | 188 | 221 | 256 | 298 | 361 | 0.0013 | 36.57 | 7.039 | 0.2500 | 54319.8 | 17300000 | 6280000000 | 2520000000000 | 0.5417 | 0.1374 | 0.0116 | 0.0006 | 0.0610 | 0.0034 | 0.1692 | 0.0206 | 0.1815 | 0.0547 | 0.2027 | 0.1259 | 0.1727 | 0.1917 | 0.1056 | 0.1593 | 0.0625 | 0.1770 | 0.0330 | 0.2666 | 0.0005 | 0.0002 | 0.0016 | 0.0004 | 0.0064 | 0.0030 | 0.0191 | 0.0101 | 0.0584 | 0.0425 | 0.1194 | 0.0871 | 0.0931 | 0.0697 | 0.1203 | 0.1000 | 0.5810 | 0.6870 | 0.0025 | 0.0036 | 0.0078 | 0.0101 | 0.0228 | 0.0258 | 0.0457 | 0.0697 | 0.1071 | 0.1403 | 0.1660 | 0.1930 | 0.1333 | 0.1409 | 0.1465 | 0.1479 | 0.3682 | 0.2686 | 0.0013 | 0.0039 | 0.0104 | 0.0303 | 0.0787 | 0.1477 | 0.1131 | 0.1412 | 0.4735 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 770 | 548 | | 4679 | 6669 | 137.8 | 37.32 | 193.13 | 136.78 | 97 | 107 | 115 | 123 | 132 | 140 | 151 | 165 | 188 | 0.1021 | 681 | 1.113 | 90.80 | 33.54 | 1 | 0.0524 | 245 | 0.0018 | 30.73 | 6.604 | 0.2167 | 20392.3 | 3250000 | 560000000 | 104000000000 | 0.4422 | 0.2057 | 0.0004 | 0.0000 | 0.0019 | 0.0000 | 0.0089 | 0.0007 | 0.0355 | 0.0024 | 0.1066 | 0.0257 | 0.1896 | 0.0591 | 0.1776 | 0.0651 | 0.1622 | 0.0905 | 0.3174 | 0.7565 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0043 | 0.0002 | 0.0097 | 0.0009 | 0.0441 | 0.0159 | 0.0819 | 0.0278 | 0.0802 | 0.0248 | 0.1044 | 0.0448 | 0.6745 | 0.8856 | 0.0054 | 0.0052 | 0.0086 | 0.0052 | 0.0119 | 0.0336 | 0.0627 | 0.1059 | 0.1568 | 0.2351 | 0.1859 | 0.2119 | 0.1092 | 0.0801 | 0.1557 | 0.1473 | 0.3038 | 0.1757 | 0.0015 | 0.0020 | 0.0085 | 0.0346 | 0.0989 | 0.1416 | 0.1145 | 0.1401 | 0.4583 | 42 | 70 | 97 | 128 | 161 | 203 | 250 | 305 | 391 | 0.0016 | 66.86 | 7.053 | 0.2296 | 56004.9 | 20500000 | 8680000000 | 4090000000000 | 0.5260 | 0.1564 | 0.0262 | 0.0016 | 0.1229 | 0.0056 | 0.2269 | 0.0334 | 0.1900 | 0.1091 | 0.1859 | 0.1851 | 0.1310 | 0.2201 | 0.0639 | 0.1584 | 0.0336 | 0.1421 | 0.0197 | 0.1445 | 0.0003 | 0.0007 | 0.0009 | 0.0007 | 0.0067 | 0.0024 | 0.0188 | 0.0163 | 0.0733 | 0.0544 | 0.1196 | 0.0928 | 0.0999 | 0.0728 | 0.1330 | 0.1079 | 0.5475 | 0.6521 | 0.0022 | 0.0017 | 0.0045 | 0.0063 | 0.0085 | 0.0150 | 0.0368 | 0.0600 | 0.1188 | 0.1298 | 0.1645 | 0.1997 | 0.1215 | 0.1298 | 0.1551 | 0.1558 | 0.3882 | 0.3018 | 0.0011 | 0.0032 | 0.0056 | 0.0275 | 0.0898 | 0.1479 | 0.1127 | 0.1437 | 0.4687 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1240 | 782 | | 5520 | 5479 | 133.2 | 23.75 | 110.66 | 100.88 | 104 | 113 | 119 | 126 | 132 | 138 | 144 | 152 | 163 | 0.1374 | 753 | 0.999 | 91.29 | 24.70 | 1 | 0.0397 | 219 | 0.0031 | 14.38 | 6.066 | 0.2851 | 18294.8 | 2590000 | 379000000 | 57200000000 | 0.4125 | 0.2388 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0002 | 0.0212 | 0.0007 | 0.0442 | 0.0156 | 0.0934 | 0.0282 | 0.1204 | 0.0252 | 0.1646 | 0.0404 | 0.5507 | 0.8897 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0083 | 0.0002 | 0.0228 | 0.0129 | 0.0452 | 0.0203 | 0.0504 | 0.0132 | 0.0765 | 0.0234 | 0.7949 | 0.9300 | 0.0226 | 0.0169 | 0.0155 | 0.0763 | 0.0523 | 0.1102 | 0.1088 | 0.1102 | 0.1638 | 0.1525 | 0.1723 | 0.2034 | 0.1201 | 0.1356 | 0.1554 | 0.0847 | 0.1893 | 0.1102 | 0.0033 | 0.0089 | 0.0118 | 0.0380 | 0.0687 | 0.1048 | 0.1063 | 0.1384 | 0.5197 | 27 | 36 | 47 | 60 | 75 | 95 | 123 | 168 | 249 | 0.0062 | 29.53 | 5.971 | 0.3642 | 22419.6 | 6640000 | 2430000000 | 1010000000000 | 0.6287 | 0.0903 | 0.0259 | 0.0043 | 0.1147 | 0.0103 | 0.2160 | 0.0511 | 0.1732 | 0.0983 | 0.1395 | 0.1836 | 0.1192 | 0.1825 | 0.0934 | 0.1477 | 0.0742 | 0.1266 | 0.0439 | 0.1955 | 0.0017 | 0.0020 | 0.0034 | 0.0039 | 0.0089 | 0.0098 | 0.0326 | 0.0219 | 0.0852 | 0.0732 | 0.1360 | 0.1023 | 0.1004 | 0.0859 | 0.1513 | 0.1366 | 0.4805 | 0.5644 | 0.0020 | 0.0025 | 0.0095 | 0.0033 | 0.0102 | 0.0172 | 0.0428 | 0.0582 | 0.1292 | 0.1534 | 0.1747 | 0.1838 | 0.1237 | 0.1017 | 0.1475 | 0.1403 | 0.3603 | 0.3396 | 0.0016 | 0.0064 | 0.0155 | 0.0321 | 0.1095 | 0.1474 | 0.1239 | 0.1394 | 0.4241 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 343 | 118 | | 16901 | 26398 | 141.3 | 44.30 | 218.23 | 252.21 | 94 | 105 | 114 | 123 | 132 | 143 | 157 | 175 | 204 | 0.0815 | 2151 | 0.681 | 101.95 | 26.17 | 6 | 0.0180 | 304 | 0.0015 | 29.37 | 6.914 | 0.2233 | 21941.5 | 3740000 | 696000000 | 140000000000 | 0.5305 | 0.1501 | 0.0011 | 0.0003 | 0.0048 | 0.0008 | 0.0158 | 0.0020 | 0.0410 | 0.0075 | 0.1072 | 0.0328 | 0.1650 | 0.0728 | 0.1666 | 0.0720 | 0.1890 | 0.1025 | 0.3095 | 0.7093 | 0.0006 | 0.0002 | 0.0026 | 0.0004 | 0.0058 | 0.0011 | 0.0146 | 0.0036 | 0.0408 | 0.0175 | 0.0693 | 0.0366 | 0.0679 | 0.0300 | 0.0954 | 0.0486 | 0.7030 | 0.8620 | 0.0021 | 0.0030 | 0.0070 | 0.0090 | 0.0120 | 0.0200 | 0.0527 | 0.0656 | 0.1020 | 0.1512 | 0.1411 | 0.1773 | 0.1049 | 0.1097 | 0.1331 | 0.1607 | 0.4451 | 0.3035 | 0.0015 | 0.0049 | 0.0131 | 0.0289 | 0.0754 | 0.1125 | 0.0940 | 0.1202 | 0.5495 | 20 | 29 | 48 | 79 | 120 | 175 | 259 | 375 | 570 | 0.0118 | 66.19 | 6.470 | 0.3644 | 111232.0 | 85900000 | 88000000000 | 113000000000000 | 0.5942 | 0.0903 | 0.0589 | 0.0022 | 0.1898 | 0.0187 | 0.2385 | 0.1095 | 0.1625 | 0.1457 | 0.1298 | 0.1893 | 0.1051 | 0.1818 | 0.0549 | 0.1192 | 0.0407 | 0.1100 | 0.0196 | 0.1236 | 0.0006 | 0.0005 | 0.0022 | 0.0016 | 0.0043 | 0.0051 | 0.0185 | 0.0152 | 0.0708 | 0.0630 | 0.1147 | 0.0979 | 0.0818 | 0.0754 | 0.1208 | 0.1064 | 0.5863 | 0.6349 | 0.0003 | 0.0018 | 0.0031 | 0.0043 | 0.0077 | 0.0110 | 0.0323 | 0.0372 | 0.0907 | 0.0969 | 0.1399 | 0.1479 | 0.1021 | 0.1013 | 0.1285 | 0.1341 | 0.4956 | 0.4656 | 0.0010 | 0.0025 | 0.0059 | 0.0245 | 0.0763 | 0.1324 | 0.0895 | 0.1228 | 0.5449 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 324 | 442 | | 5445 | 9682 | 138.7 | 35.79 | 163.09 | 136.98 | 98 | 109 | 117 | 125 | 133 | 142 | 152 | 165 | 188 | 0.0876 | 848 | 1.068 | 95.72 | 31.26 | 1 | 0.0455 | 248 | 0.0019 | 26.13 | 6.600 | 0.2423 | 20529.1 | 3240000 | 545000000 | 97400000000 | 0.4118 | 0.2366 | 0.0003 | 0.0000 | 0.0022 | 0.0000 | 0.0119 | 0.0004 | 0.0372 | 0.0029 | 0.0985 | 0.0264 | 0.1691 | 0.0554 | 0.1649 | 0.0532 | 0.1854 | 0.0975 | 0.3304 | 0.7642 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0034 | 0.0000 | 0.0149 | 0.0009 | 0.0434 | 0.0150 | 0.0739 | 0.0264 | 0.0730 | 0.0186 | 0.1034 | 0.0390 | 0.6871 | 0.9000 | 0.0057 | 0.0136 | 0.0086 | 0.0181 | 0.0114 | 0.0317 | 0.0762 | 0.1134 | 0.1495 | 0.1950 | 0.1733 | 0.2109 | 0.1343 | 0.1293 | 0.1476 | 0.1383 | 0.2933 | 0.1497 | 0.0017 | 0.0033 | 0.0130 | 0.0401 | 0.0794 | 0.1216 | 0.1057 | 0.1358 | 0.4994 | 19 | 42 | 68 | 95 | 129 | 166 | 213 | 270 | 358 | 0.0040 | 66.08 | 6.940 | 0.2888 | 45362.2 | 16600000 | 7290000000 | 3700000000000 | 0.5293 | 0.1340 | 0.0265 | 0.0026 | 0.1297 | 0.0115 | 0.2310 | 0.0590 | 0.1394 | 0.1144 | 0.1490 | 0.1576 | 0.1355 | 0.1769 | 0.0839 | 0.1439 | 0.0606 | 0.1362 | 0.0445 | 0.1980 | 0.0006 | 0.0004 | 0.0010 | 0.0018 | 0.0023 | 0.0033 | 0.0177 | 0.0117 | 0.0586 | 0.0526 | 0.1291 | 0.0966 | 0.0780 | 0.0741 | 0.1126 | 0.0990 | 0.5999 | 0.6605 | 0.0015 | 0.0019 | 0.0018 | 0.0054 | 0.0111 | 0.0151 | 0.0348 | 0.0414 | 0.0860 | 0.1056 | 0.1631 | 0.1698 | 0.1002 | 0.0928 | 0.1236 | 0.1381 | 0.4778 | 0.4298 | 0.0010 | 0.0018 | 0.0061 | 0.0244 | 0.0786 | 0.1389 | 0.0972 | 0.1322 | 0.5198 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 271 | 234 | | 4849 | 8509 | 138.5 | 37.61 | 168.08 | 116.27 | 97 | 108 | 116 | 125 | 133 | 143 | 153 | 166 | 185 | 0.0903 | 768 | 0.853 | 97.87 | 27.20 | 1 | 0.0524 | 254 | 0.0019 | 23.69 | 6.561 | 0.2428 | 20609.1 | 3310000 | 576000000 | 109000000000 | 0.4479 | 0.1970 | 0.0011 | 0.0000 | 0.0041 | 0.0000 | 0.0103 | 0.0007 | 0.0347 | 0.0030 | 0.0975 | 0.0240 | 0.1680 | 0.0552 | 0.1473 | 0.0550 | 0.1743 | 0.0965 | 0.3626 | 0.7657 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0030 | 0.0000 | 0.0123 | 0.0013 | 0.0355 | 0.0161 | 0.0695 | 0.0309 | 0.0711 | 0.0237 | 0.0993 | 0.0428 | 0.7066 | 0.8852 | 0.0042 | 0.0206 | 0.0084 | 0.0413 | 0.0190 | 0.0324 | 0.0685 | 0.1150 | 0.1496 | 0.1711 | 0.1707 | 0.1917 | 0.1201 | 0.1003 | 0.1465 | 0.0944 | 0.3130 | 0.2330 | 0.0009 | 0.0047 | 0.0117 | 0.0314 | 0.0835 | 0.1234 | 0.1183 | 0.1427 | 0.4833 | 38 | 66 | 89 | 113 | 143 | 180 | 216 | 263 | 330 | 0.0018 | 46.51 | 6.975 | 0.2588 | 41766.1 | 13000000 | 4740000000 | 1930000000000 | 0.4999 | 0.1620 | 0.0124 | 0.0018 | 0.0599 | 0.0036 | 0.1785 | 0.0173 | 0.2094 | 0.0574 | 0.1872 | 0.1344 | 0.1408 | 0.2044 | 0.0982 | 0.1652 | 0.0624 | 0.1709 | 0.0513 | 0.2450 | 0.0000 | 0.0005 | 0.0009 | 0.0009 | 0.0025 | 0.0038 | 0.0156 | 0.0096 | 0.0467 | 0.0356 | 0.0847 | 0.0597 | 0.0774 | 0.0637 | 0.1241 | 0.0957 | 0.6481 | 0.7305 | 0.0014 | 0.0023 | 0.0028 | 0.0064 | 0.0084 | 0.0138 | 0.0298 | 0.0527 | 0.0922 | 0.1087 | 0.1388 | 0.1577 | 0.1247 | 0.1220 | 0.1496 | 0.1298 | 0.4523 | 0.4067 | 0.0000 | 0.0008 | 0.0024 | 0.0176 | 0.0680 | 0.1114 | 0.0973 | 0.1403 | 0.5622 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1135 | 892 | | 1409 | 5293 | 134.3 | 28.05 | 123.64 | 119.19 | 100 | 110 | 119 | 126 | 133 | 139 | 146 | 156 | 174 | 0.1398 | 740 | 0.560 | 124.49 | 24.84 | 1 | 0.2342 | 330 | 0.0027 | 21.21 | 6.129 | 0.2523 | 18811.5 | 2740000 | 416000000 | 65400000000 | 0.4105 | 0.2378 | 0.0011 | 0.0000 | 0.0043 | 0.0000 | 0.0075 | 0.0015 | 0.0247 | 0.0053 | 0.0816 | 0.0356 | 0.1633 | 0.0734 | 0.1429 | 0.0552 | 0.1665 | 0.0953 | 0.4082 | 0.7337 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0120 | 0.0036 | 0.0463 | 0.0252 | 0.0892 | 0.0533 | 0.0729 | 0.0259 | 0.0892 | 0.0497 | 0.6861 | 0.8423 | 0.0043 | 0.0000 | 0.0043 | 0.0746 | 0.0468 | 0.1493 | 0.0766 | 0.2239 | 0.1489 | 0.2388 | 0.1362 | 0.1045 | 0.0894 | 0.0896 | 0.1574 | 0.0746 | 0.3362 | 0.0448 | 0.0029 | 0.0044 | 0.0190 | 0.0452 | 0.0860 | 0.1472 | 0.1297 | 0.1356 | 0.4300 | 24 | 32 | 40 | 53 | 72 | 105 | 153 | 214 | 303 | 0.0149 | 12.61 | 5.403 | 0.4666 | 29488.2 | 9730000 | 3860000000 | 1750000000000 | 0.6071 | 0.1012 | 0.0703 | 0.0066 | 0.2148 | 0.0303 | 0.2890 | 0.0917 | 0.1787 | 0.1523 | 0.1274 | 0.1941 | 0.0837 | 0.2007 | 0.0209 | 0.1302 | 0.0114 | 0.1007 | 0.0038 | 0.0934 | 0.0009 | 0.0015 | 0.0032 | 0.0035 | 0.0111 | 0.0112 | 0.0263 | 0.0235 | 0.0783 | 0.0666 | 0.1188 | 0.1150 | 0.0866 | 0.0850 | 0.1152 | 0.1070 | 0.5597 | 0.5868 | 0.0000 | 0.0036 | 0.0043 | 0.0065 | 0.0201 | 0.0203 | 0.0419 | 0.0443 | 0.0906 | 0.1074 | 0.1404 | 0.1350 | 0.1021 | 0.1103 | 0.1319 | 0.1321 | 0.4687 | 0.4405 | 0.0016 | 0.0037 | 0.0058 | 0.0288 | 0.0885 | 0.1257 | 0.0927 | 0.1225 | 0.5309 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 658 | 779 | | 5169 | 11172 | 137.7 | 32.46 | 113.17 | 91.87 | 100 | 111 | 120 | 127 | 134 | 142 | 150 | 160 | 178 | 0.0719 | 803 | 0.859 | 104.81 | 28.16 | 1 | 0.0530 | 274 | 0.0021 | 21.91 | 6.455 | 0.2447 | 20003.2 | 3080000 | 502000000 | 87100000000 | 0.4380 | 0.2131 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0072 | 0.0000 | 0.0208 | 0.0021 | 0.0760 | 0.0199 | 0.1417 | 0.0475 | 0.1466 | 0.0488 | 0.1981 | 0.0785 | 0.4089 | 0.8031 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0077 | 0.0008 | 0.0363 | 0.0134 | 0.0672 | 0.0294 | 0.0593 | 0.0203 | 0.0997 | 0.0401 | 0.7272 | 0.8959 | 0.0081 | 0.0139 | 0.0185 | 0.0209 | 0.0288 | 0.0453 | 0.0819 | 0.1603 | 0.1453 | 0.1672 | 0.1926 | 0.1812 | 0.1119 | 0.0836 | 0.1407 | 0.1324 | 0.2722 | 0.1951 | 0.0025 | 0.0042 | 0.0148 | 0.0420 | 0.0954 | 0.1238 | 0.1081 | 0.1361 | 0.4731 | 15 | 30 | 49 | 70 | 92 | 118 | 149 | 185 | 238 | 0.0049 | 34.56 | 6.477 | 0.3146 | 21247.0 | 5290000 | 1630000000 | 593000000000 | 0.5230 | 0.1320 | 0.0237 | 0.0013 | 0.1084 | 0.0065 | 0.2323 | 0.0500 | 0.1730 | 0.0940 | 0.1806 | 0.1655 | 0.1412 | 0.2079 | 0.0846 | 0.1542 | 0.0415 | 0.1364 | 0.0146 | 0.1841 | 0.0004 | 0.0003 | 0.0009 | 0.0000 | 0.0057 | 0.0022 | 0.0210 | 0.0114 | 0.0670 | 0.0515 | 0.1169 | 0.0950 | 0.0867 | 0.0772 | 0.1217 | 0.1026 | 0.5799 | 0.6597 | 0.0011 | 0.0007 | 0.0029 | 0.0076 | 0.0111 | 0.0152 | 0.0315 | 0.0444 | 0.0978 | 0.1136 | 0.1574 | 0.1758 | 0.0999 | 0.1242 | 0.1479 | 0.1351 | 0.4505 | 0.3834 | 0.0009 | 0.0021 | 0.0064 | 0.0277 | 0.0813 | 0.1285 | 0.1054 | 0.1321 | 0.5156 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 418 | 234 | | 17233 | 30716 | 142.7 | 48.74 | 171.07 | 136.88 | 91 | 103 | 113 | 123 | 134 | 146 | 159 | 179 | 208 | 0.0589 | 1808 | 0.875 | 171.23 | 50.54 | 6 | 0.0257 | 443 | 0.0012 | 32.99 | 7.078 | 0.2149 | 22747.1 | 4030000 | 792000000 | 170000000000 | 0.4209 | 0.2369 | 0.0013 | 0.0001 | 0.0039 | 0.0003 | 0.0174 | 0.0014 | 0.0505 | 0.0050 | 0.1309 | 0.0315 | 0.1949 | 0.0683 | 0.1734 | 0.0758 | 0.1834 | 0.1141 | 0.2444 | 0.7035 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0058 | 0.0006 | 0.0141 | 0.0022 | 0.0490 | 0.0156 | 0.0844 | 0.0320 | 0.0765 | 0.0347 | 0.0991 | 0.0569 | 0.6692 | 0.8578 | 0.0040 | 0.0044 | 0.0055 | 0.0098 | 0.0144 | 0.0186 | 0.0431 | 0.0667 | 0.1096 | 0.1382 | 0.1445 | 0.1770 | 0.1086 | 0.1078 | 0.1442 | 0.1436 | 0.4260 | 0.3338 | 0.0011 | 0.0020 | 0.0089 | 0.0326 | 0.0833 | 0.1183 | 0.0961 | 0.1280 | 0.5296 | 21 | 42 | 74 | 109 | 144 | 182 | 223 | 278 | 356 | 0.0059 | 37.42 | 6.647 | 0.3123 | 47999.4 | 17500000 | 7750000000 | 3980000000000 | 0.5887 | 0.1133 | 0.0187 | 0.0011 | 0.0941 | 0.0056 | 0.1941 | 0.0281 | 0.1770 | 0.0790 | 0.1770 | 0.1591 | 0.1489 | 0.1991 | 0.0907 | 0.1550 | 0.0639 | 0.1574 | 0.0358 | 0.2154 | 0.0003 | 0.0001 | 0.0018 | 0.0009 | 0.0044 | 0.0024 | 0.0138 | 0.0084 | 0.0576 | 0.0421 | 0.1092 | 0.0858 | 0.0878 | 0.0696 | 0.1288 | 0.1035 | 0.5963 | 0.6873 | 0.0013 | 0.0017 | 0.0050 | 0.0076 | 0.0119 | 0.0155 | 0.0341 | 0.0397 | 0.0958 | 0.1103 | 0.1473 | 0.1630 | 0.1089 | 0.1127 | 0.1449 | 0.1590 | 0.4508 | 0.3906 | 0.0007 | 0.0032 | 0.0079 | 0.0194 | 0.0783 | 0.1344 | 0.1013 | 0.1353 | 0.5195 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 293 | 128 | | 4381 | 3891 | 142.2 | 45.53 | 116.54 | 68.03 | 93 | 105 | 115 | 124 | 134 | 144 | 156 | 174 | 206 | 0.1773 | 690 | 1.154 | 92.96 | 30.48 | 1 | 0.0539 | 236 | 0.0014 | 45.81 | 6.878 | 0.1869 | 22305.5 | 3870000 | 744000000 | 158000000000 | 0.4152 | 0.2335 | 0.0000 | 0.0000 | 0.0045 | 0.0003 | 0.0186 | 0.0022 | 0.0626 | 0.0091 | 0.1392 | 0.0365 | 0.1946 | 0.0890 | 0.1642 | 0.0862 | 0.1655 | 0.1307 | 0.2508 | 0.6460 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0038 | 0.0010 | 0.0190 | 0.0034 | 0.0514 | 0.0191 | 0.0936 | 0.0528 | 0.0787 | 0.0396 | 0.1148 | 0.0671 | 0.6372 | 0.8169 | 0.0021 | 0.0099 | 0.0063 | 0.0079 | 0.0264 | 0.0258 | 0.0738 | 0.0813 | 0.1276 | 0.1488 | 0.1762 | 0.1925 | 0.1171 | 0.1310 | 0.1403 | 0.1587 | 0.3302 | 0.2440 | 0.0016 | 0.0054 | 0.0136 | 0.0490 | 0.1017 | 0.1447 | 0.1181 | 0.1371 | 0.4287 | 38 | 55 | 71 | 88 | 106 | 126 | 145 | 172 | 209 | 0.0023 | 29.24 | 6.422 | 0.2512 | 18208.7 | 3510000 | 804000000 | 216000000000 | 0.4985 | 0.1471 | 0.0212 | 0.0005 | 0.0945 | 0.0070 | 0.1741 | 0.0289 | 0.1656 | 0.0690 | 0.1975 | 0.1573 | 0.1592 | 0.1669 | 0.0902 | 0.1493 | 0.0637 | 0.1728 | 0.0340 | 0.2483 | 0.0018 | 0.0000 | 0.0041 | 0.0011 | 0.0091 | 0.0040 | 0.0279 | 0.0190 | 0.0741 | 0.0623 | 0.1189 | 0.0845 | 0.1006 | 0.0758 | 0.1161 | 0.1217 | 0.5473 | 0.6316 | 0.0048 | 0.0023 | 0.0088 | 0.0137 | 0.0201 | 0.0286 | 0.0530 | 0.0766 | 0.1349 | 0.1646 | 0.1743 | 0.1737 | 0.1245 | 0.1234 | 0.1414 | 0.1349 | 0.3382 | 0.2823 | 0.0006 | 0.0069 | 0.0103 | 0.0322 | 0.0925 | 0.1516 | 0.1040 | 0.1338 | 0.4681 | ||
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 925 | 483 | | 3069 | 17112 | 133.0 | 40.22 | 103.86 | 203.05 | 76 | 97 | 114 | 125 | 135 | 144 | 156 | 169 | 185 | 0.0464 | 794 | 0.346 | 113.00 | 13.45 | 1 | 0.1036 | 318 | 0.0020 | 15.03 | 6.464 | 0.2683 | 19308.7 | 2990000 | 486000000 | 82200000000 | 0.3770 | 0.2497 | 0.0000 | 0.0000 | 0.0061 | 0.0008 | 0.0067 | 0.0008 | 0.0223 | 0.0066 | 0.0756 | 0.0370 | 0.1201 | 0.0555 | 0.1066 | 0.0588 | 0.1296 | 0.0867 | 0.5331 | 0.7538 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0004 | 0.0004 | 0.0065 | 0.0033 | 0.0230 | 0.0218 | 0.0390 | 0.0336 | 0.0295 | 0.0251 | 0.0464 | 0.0369 | 0.8553 | 0.8783 | 0.0000 | 0.0072 | 0.0036 | 0.0036 | 0.0109 | 0.0324 | 0.0339 | 0.0755 | 0.0593 | 0.1547 | 0.1186 | 0.1007 | 0.1005 | 0.1583 | 0.1223 | 0.1151 | 0.5508 | 0.3525 | 0.0006 | 0.0006 | 0.0031 | 0.0161 | 0.0433 | 0.0644 | 0.0718 | 0.0934 | 0.7067 | 11 | 13 | 16 | 21 | 29 | 46 | 76 | 134 | 243 | 0.0626 | 20.97 | 4.597 | 0.5710 | 52014.4 | 50700000 | 63400000000 | 88800000000000 | 0.5552 | 0.1464 | 0.0385 | 0.0020 | 0.1709 | 0.0137 | 0.2873 | 0.1186 | 0.1533 | 0.1182 | 0.1415 | 0.1703 | 0.1114 | 0.2121 | 0.0427 | 0.1186 | 0.0369 | 0.1014 | 0.0176 | 0.1452 | 0.0004 | 0.0007 | 0.0010 | 0.0017 | 0.0045 | 0.0040 | 0.0170 | 0.0154 | 0.0622 | 0.0508 | 0.1379 | 0.1125 | 0.0614 | 0.0648 | 0.0821 | 0.0786 | 0.6335 | 0.6716 | 0.0014 | 0.0009 | 0.0049 | 0.0060 | 0.0140 | 0.0158 | 0.0198 | 0.0211 | 0.0673 | 0.0687 | 0.1389 | 0.1378 | 0.0579 | 0.0627 | 0.0826 | 0.0880 | 0.6132 | 0.5990 | 0.0005 | 0.0036 | 0.0082 | 0.0192 | 0.0694 | 0.1387 | 0.0634 | 0.0742 | 0.6229 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 324 | 200 | | 9267 | 28546 | 136.9 | 41.75 | 161.87 | 233.98 | 86 | 99 | 112 | 124 | 135 | 146 | 158 | 172 | 193 | 0.0455 | 1300 | 0.914 | 69.01 | 19.70 | 6 | 0.0181 | 168 | 0.0013 | 24.49 | 6.895 | 0.2332 | 20479.4 | 3300000 | 567000000 | 103000000000 | 0.4196 | 0.2164 | 0.0018 | 0.0000 | 0.0058 | 0.0004 | 0.0076 | 0.0017 | 0.0306 | 0.0073 | 0.1008 | 0.0279 | 0.1517 | 0.0559 | 0.1639 | 0.0691 | 0.1899 | 0.0994 | 0.3480 | 0.7382 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0018 | 0.0004 | 0.0088 | 0.0035 | 0.0321 | 0.0139 | 0.0490 | 0.0251 | 0.0522 | 0.0285 | 0.0722 | 0.0388 | 0.7809 | 0.8897 | 0.0043 | 0.0081 | 0.0086 | 0.0070 | 0.0241 | 0.0252 | 0.0455 | 0.0916 | 0.0769 | 0.1370 | 0.1327 | 0.1631 | 0.1078 | 0.1269 | 0.1430 | 0.1511 | 0.4570 | 0.2900 | 0.0011 | 0.0051 | 0.0058 | 0.0210 | 0.0568 | 0.0917 | 0.0790 | 0.1085 | 0.6310 | 20 | 25 | 32 | 42 | 59 | 88 | 146 | 248 | 465 | 0.0337 | 41.47 | 5.283 | 0.5159 | 80948.0 | 65000000 | 65600000000 | 76000000000000 | 0.5258 | 0.1466 | 0.0551 | 0.0017 | 0.1968 | 0.0211 | 0.2532 | 0.1230 | 0.1516 | 0.1351 | 0.1376 | 0.1940 | 0.0880 | 0.1858 | 0.0596 | 0.1152 | 0.0384 | 0.1031 | 0.0199 | 0.1210 | 0.0003 | 0.0001 | 0.0003 | 0.0004 | 0.0036 | 0.0018 | 0.0190 | 0.0156 | 0.0709 | 0.0590 | 0.1046 | 0.0925 | 0.0709 | 0.0629 | 0.1037 | 0.0968 | 0.6266 | 0.6709 | 0.0006 | 0.0008 | 0.0014 | 0.0019 | 0.0072 | 0.0074 | 0.0231 | 0.0271 | 0.0831 | 0.0907 | 0.1334 | 0.1460 | 0.0842 | 0.0925 | 0.1238 | 0.1209 | 0.5433 | 0.5125 | 0.0008 | 0.0026 | 0.0043 | 0.0227 | 0.0776 | 0.1148 | 0.0780 | 0.1182 | 0.5810 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 736 | 857 | | 16963 | 12738 | 140.2 | 47.70 | 284.47 | 272.42 | 86 | 103 | 115 | 125 | 135 | 146 | 159 | 175 | 199 | 0.1170 | 1490 | 0.454 | 104.36 | 26.02 | 3 | 0.0222 | 376 | 0.0013 | 28.58 | 7.013 | 0.2392 | 21921.8 | 3810000 | 736000000 | 159000000000 | 0.5138 | 0.1429 | 0.0011 | 0.0001 | 0.0046 | 0.0004 | 0.0190 | 0.0015 | 0.0417 | 0.0061 | 0.1096 | 0.0343 | 0.1753 | 0.0705 | 0.1648 | 0.0732 | 0.1725 | 0.1036 | 0.3113 | 0.7103 | 0.0003 | 0.0000 | 0.0016 | 0.0003 | 0.0030 | 0.0006 | 0.0086 | 0.0019 | 0.0379 | 0.0187 | 0.0685 | 0.0336 | 0.0683 | 0.0292 | 0.0917 | 0.0481 | 0.7201 | 0.8674 | 0.0029 | 0.0048 | 0.0072 | 0.0161 | 0.0144 | 0.0353 | 0.0503 | 0.0744 | 0.1120 | 0.1435 | 0.1511 | 0.1879 | 0.1142 | 0.0969 | 0.1336 | 0.1381 | 0.4144 | 0.3030 | 0.0010 | 0.0034 | 0.0085 | 0.0267 | 0.0777 | 0.1103 | 0.0988 | 0.1250 | 0.5485 | 17 | 30 | 70 | 134 | 213 | 299 | 394 | 506 | 659 | 0.0090 | 99.68 | 6.927 | 0.2797 | 155129.0 | 112000000 | 97700000000 | 101000000000000 | 0.5569 | 0.1416 | 0.0517 | 0.0052 | 0.1626 | 0.0189 | 0.2432 | 0.1060 | 0.1736 | 0.1157 | 0.1416 | 0.1826 | 0.1121 | 0.2064 | 0.0622 | 0.1365 | 0.0296 | 0.1148 | 0.0234 | 0.1139 | 0.0003 | 0.0000 | 0.0024 | 0.0010 | 0.0037 | 0.0030 | 0.0161 | 0.0098 | 0.0690 | 0.0611 | 0.1238 | 0.1119 | 0.0809 | 0.0760 | 0.1129 | 0.1040 | 0.5907 | 0.6331 | 0.0007 | 0.0011 | 0.0042 | 0.0032 | 0.0077 | 0.0122 | 0.0247 | 0.0416 | 0.0967 | 0.1108 | 0.1543 | 0.1728 | 0.1062 | 0.1147 | 0.1406 | 0.1433 | 0.4650 | 0.4004 | 0.0008 | 0.0013 | 0.0077 | 0.0199 | 0.0782 | 0.1419 | 0.0914 | 0.1252 | 0.5336 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1025 | 533 | | 6415 | 17497 | 136.2 | 34.04 | 109.48 | 103.79 | 91 | 104 | 115 | 126 | 135 | 145 | 155 | 165 | 181 | 0.0768 | 1343 | 1.143 | 110.98 | 37.59 | 5 | 0.0415 | 266 | 0.0020 | 17.74 | 6.447 | 0.2724 | 19709.7 | 3010000 | 484000000 | 81300000000 | 0.4281 | 0.2171 | 0.0017 | 0.0000 | 0.0060 | 0.0009 | 0.0083 | 0.0029 | 0.0252 | 0.0062 | 0.0809 | 0.0210 | 0.1181 | 0.0496 | 0.1378 | 0.0503 | 0.1704 | 0.0722 | 0.4515 | 0.7970 | 0.0002 | 0.0000 | 0.0023 | 0.0005 | 0.0016 | 0.0016 | 0.0072 | 0.0042 | 0.0297 | 0.0146 | 0.0462 | 0.0299 | 0.0467 | 0.0256 | 0.0632 | 0.0341 | 0.8029 | 0.8896 | 0.0050 | 0.0107 | 0.0137 | 0.0134 | 0.0281 | 0.0588 | 0.0518 | 0.1070 | 0.0978 | 0.1765 | 0.1259 | 0.2005 | 0.1295 | 0.1150 | 0.1489 | 0.1283 | 0.3993 | 0.1898 | 0.0003 | 0.0025 | 0.0041 | 0.0194 | 0.0484 | 0.0871 | 0.0787 | 0.1052 | 0.6544 | 23 | 35 | 46 | 58 | 72 | 92 | 123 | 171 | 248 | 0.0137 | 12.49 | 5.314 | 0.4876 | 22756.3 | 7180000 | 2950000000 | 1450000000000 | 0.5455 | 0.1639 | 0.0152 | 0.0037 | 0.0629 | 0.0119 | 0.1464 | 0.0290 | 0.2021 | 0.0594 | 0.2186 | 0.1394 | 0.1738 | 0.1927 | 0.0924 | 0.1541 | 0.0557 | 0.1495 | 0.0329 | 0.2603 | 0.0008 | 0.0018 | 0.0032 | 0.0044 | 0.0073 | 0.0078 | 0.0221 | 0.0165 | 0.0575 | 0.0523 | 0.0972 | 0.0769 | 0.0694 | 0.0675 | 0.0930 | 0.0837 | 0.6497 | 0.6889 | 0.0020 | 0.0015 | 0.0045 | 0.0037 | 0.0134 | 0.0110 | 0.0213 | 0.0282 | 0.0764 | 0.0849 | 0.1103 | 0.1288 | 0.0855 | 0.0952 | 0.1156 | 0.1242 | 0.5710 | 0.5225 | 0.0015 | 0.0052 | 0.0074 | 0.0247 | 0.0649 | 0.1051 | 0.0778 | 0.1034 | 0.6100 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 166 | 253 | | 6270 | 6263 | 146.8 | 53.83 | 210.83 | 195.38 | 91 | 105 | 116 | 126 | 136 | 148 | 163 | 183 | 214 | 0.1284 | 804 | 0.784 | 97.01 | 20.88 | 2 | 0.0364 | 228 | 0.0012 | 46.26 | 7.074 | 0.1935 | 24453.4 | 4680000 | 1040000000 | 271000000000 | 0.4725 | 0.1765 | 0.0007 | 0.0000 | 0.0042 | 0.0002 | 0.0251 | 0.0014 | 0.0639 | 0.0074 | 0.1432 | 0.0380 | 0.2040 | 0.0897 | 0.1788 | 0.0986 | 0.1596 | 0.1272 | 0.2204 | 0.6374 | 0.0005 | 0.0000 | 0.0007 | 0.0002 | 0.0037 | 0.0007 | 0.0128 | 0.0035 | 0.0536 | 0.0227 | 0.0951 | 0.0435 | 0.0820 | 0.0411 | 0.1203 | 0.0647 | 0.6313 | 0.8237 | 0.0000 | 0.0027 | 0.0028 | 0.0199 | 0.0231 | 0.0292 | 0.0651 | 0.1089 | 0.1254 | 0.1169 | 0.1779 | 0.2058 | 0.1036 | 0.0943 | 0.1359 | 0.1262 | 0.3662 | 0.2961 | 0.0012 | 0.0042 | 0.0089 | 0.0386 | 0.0981 | 0.1463 | 0.1035 | 0.1332 | 0.4660 | 38 | 58 | 81 | 110 | 146 | 193 | 254 | 331 | 478 | 0.0038 | 52.97 | 6.523 | 0.2940 | 82615.2 | 46500000 | 32400000000 | 25600000000000 | 0.5390 | 0.1222 | 0.0251 | 0.0021 | 0.1137 | 0.0098 | 0.2109 | 0.0602 | 0.1891 | 0.0932 | 0.1683 | 0.1720 | 0.1311 | 0.1941 | 0.0678 | 0.1478 | 0.0612 | 0.1313 | 0.0328 | 0.1895 | 0.0004 | 0.0003 | 0.0021 | 0.0012 | 0.0039 | 0.0043 | 0.0189 | 0.0162 | 0.0754 | 0.0638 | 0.1190 | 0.1070 | 0.0829 | 0.0786 | 0.1187 | 0.1041 | 0.5786 | 0.6246 | 0.0011 | 0.0013 | 0.0016 | 0.0040 | 0.0080 | 0.0153 | 0.0366 | 0.0477 | 0.1115 | 0.1194 | 0.1476 | 0.1472 | 0.1041 | 0.1154 | 0.1391 | 0.1366 | 0.4503 | 0.4131 | 0.0009 | 0.0004 | 0.0043 | 0.0272 | 0.0858 | 0.1337 | 0.0923 | 0.1251 | 0.5302 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 68 | 826 | | 4128 | 6864 | 146.8 | 44.75 | 144.31 | 126.93 | 100 | 110 | 118 | 127 | 136 | 147 | 160 | 181 | 211 | 0.1005 | 690 | 1.168 | 86.40 | 31.91 | 1 | 0.0540 | 223 | 0.0017 | 33.02 | 6.715 | 0.2229 | 23554.4 | 4140000 | 797000000 | 166000000000 | 0.3837 | 0.2702 | 0.0030 | 0.0000 | 0.0044 | 0.0000 | 0.0178 | 0.0020 | 0.0435 | 0.0054 | 0.1156 | 0.0363 | 0.1789 | 0.0632 | 0.1848 | 0.0697 | 0.1912 | 0.1133 | 0.2609 | 0.7102 | 0.0021 | 0.0000 | 0.0021 | 0.0000 | 0.0065 | 0.0008 | 0.0174 | 0.0018 | 0.0533 | 0.0206 | 0.0793 | 0.0323 | 0.0854 | 0.0354 | 0.1083 | 0.0652 | 0.6456 | 0.8440 | 0.0011 | 0.0066 | 0.0033 | 0.0087 | 0.0299 | 0.0175 | 0.0421 | 0.0611 | 0.0965 | 0.1332 | 0.1275 | 0.1681 | 0.0976 | 0.1201 | 0.1197 | 0.1638 | 0.4823 | 0.3210 | 0.0024 | 0.0042 | 0.0180 | 0.0342 | 0.0792 | 0.1104 | 0.0870 | 0.1309 | 0.5336 | 30 | 44 | 59 | 79 | 101 | 131 | 171 | 232 | 322 | 0.0037 | 48.50 | 6.480 | 0.3040 | 36934.0 | 13300000 | 5910000000 | 3030000000000 | 0.5053 | 0.1536 | 0.0289 | 0.0009 | 0.1252 | 0.0109 | 0.1753 | 0.0639 | 0.1667 | 0.0948 | 0.1830 | 0.1501 | 0.1532 | 0.1791 | 0.0886 | 0.1497 | 0.0559 | 0.1542 | 0.0231 | 0.1964 | 0.0016 | 0.0003 | 0.0026 | 0.0026 | 0.0078 | 0.0059 | 0.0260 | 0.0221 | 0.0809 | 0.0635 | 0.1135 | 0.0910 | 0.0891 | 0.0846 | 0.1135 | 0.1116 | 0.5650 | 0.6183 | 0.0020 | 0.0018 | 0.0025 | 0.0077 | 0.0088 | 0.0196 | 0.0471 | 0.0422 | 0.0972 | 0.1040 | 0.1290 | 0.1337 | 0.1035 | 0.1040 | 0.1295 | 0.1349 | 0.4804 | 0.4522 | 0.0000 | 0.0060 | 0.0116 | 0.0344 | 0.0800 | 0.1244 | 0.1000 | 0.1224 | 0.5214 |