High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1189 | 733 | 6368 | 8540 | 460.5 | 95.33 | 276.86 | 365.75 | 341 | 370 | 398 | 426 | 449 | 474 | 509 | 550 | 597 | 0.0848 | 724 | 0.776 | 177.72 | 41.62 | 1 | 0.0785 | 500 | 0.0009 | 23.98 | 7.222 | 0.2306 | 221183.0 | 111000000 | 57400000000 | 30900000000000 | 0.4039 | 0.2350 | 0.0005 | 0.0000 | 0.0020 | 0.0003 | 0.0059 | 0.0005 | 0.0136 | 0.0018 | 0.0358 | 0.0143 | 0.0491 | 0.0278 | 0.0573 | 0.0203 | 0.0893 | 0.0345 | 0.7465 | 0.9005 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0021 | 0.0000 | 0.0072 | 0.0005 | 0.0145 | 0.0099 | 0.0191 | 0.0206 | 0.0217 | 0.0093 | 0.0320 | 0.0179 | 0.9023 | 0.9419 | 0.0074 | 0.0186 | 0.0017 | 0.0372 | 0.0124 | 0.0558 | 0.0314 | 0.0884 | 0.0553 | 0.1023 | 0.0677 | 0.1395 | 0.0619 | 0.1302 | 0.0958 | 0.1535 | 0.6664 | 0.2744 | 0.0003 | 0.0024 | 0.0069 | 0.0180 | 0.0340 | 0.0506 | 0.0544 | 0.0634 | 0.7698 | 9 | 12 | 16 | 59 | 118 | 196 | 330 | 523 | 797 | 0.0654 | 101.98 | 5.746 | 0.4428 | 210404.0 | 226000000 | 301000000000 | 467000000000000 | 0.4431 | 0.2080 | 0.0250 | 0.0028 | 0.1591 | 0.0106 | 0.2872 | 0.0700 | 0.1944 | 0.1272 | 0.1399 | 0.1965 | 0.1046 | 0.2367 | 0.0442 | 0.1357 | 0.0339 | 0.1074 | 0.0118 | 0.1131 | 0.0000 | 0.0000 | 0.0006 | 0.0011 | 0.0028 | 0.0030 | 0.0130 | 0.0116 | 0.0551 | 0.0462 | 0.0740 | 0.0648 | 0.0688 | 0.0562 | 0.0988 | 0.0759 | 0.6869 | 0.7413 | 0.0008 | 0.0004 | 0.0016 | 0.0026 | 0.0035 | 0.0044 | 0.0208 | 0.0219 | 0.0631 | 0.0804 | 0.1145 | 0.1307 | 0.0922 | 0.0979 | 0.1196 | 0.1281 | 0.5839 | 0.5337 | 0.0000 | 0.0011 | 0.0032 | 0.0151 | 0.0601 | 0.0984 | 0.0766 | 0.1131 | 0.6325 | |
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 512 | 618 | 11255 | 20255 | 428.2 | 87.05 | 105.63 | 203.30 | 309 | 354 | 384 | 408 | 429 | 449 | 474 | 501 | 549 | 0.0544 | 1102 | 0.683 | 111.73 | 25.46 | 6 | 0.0275 | 310 | 0.0009 | 22.99 | 7.263 | 0.2438 | 190902.0 | 88200000 | 42000000000 | 20600000000000 | 0.4424 | 0.2031 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0026 | 0.0004 | 0.0084 | 0.0012 | 0.0280 | 0.0134 | 0.0584 | 0.0238 | 0.0474 | 0.0178 | 0.0713 | 0.0278 | 0.7829 | 0.9155 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0033 | 0.0008 | 0.0135 | 0.0104 | 0.0281 | 0.0209 | 0.0204 | 0.0124 | 0.0313 | 0.0184 | 0.9022 | 0.9370 | 0.0011 | 0.0000 | 0.0063 | 0.0000 | 0.0110 | 0.0000 | 0.0226 | 0.0000 | 0.0479 | 0.0000 | 0.0805 | 0.0000 | 0.0642 | 0.0000 | 0.0789 | 0.0000 | 0.6875 | 0.0000 | 0.0009 | 0.0019 | 0.0058 | 0.0140 | 0.0333 | 0.0539 | 0.0552 | 0.0744 | 0.7606 | 8 | 9 | 10 | 11 | 13 | 16 | 42 | 145 | 378 | 0.0720 | 5.26 | 3.153 | 0.4465 | 52486.1 | 36900000 | 30400000000 | 27900000000000 | 0.5667 | 0.1091 | 0.0648 | 0.0042 | 0.2221 | 0.0305 | 0.2455 | 0.1491 | 0.1821 | 0.1574 | 0.1255 | 0.1533 | 0.0690 | 0.1678 | 0.0331 | 0.1262 | 0.0317 | 0.0846 | 0.0262 | 0.1269 | 0.0004 | 0.0000 | 0.0006 | 0.0006 | 0.0010 | 0.0017 | 0.0112 | 0.0092 | 0.0467 | 0.0430 | 0.0696 | 0.0628 | 0.0485 | 0.0415 | 0.0752 | 0.0685 | 0.7467 | 0.7729 | 0.0005 | 0.0005 | 0.0007 | 0.0007 | 0.0016 | 0.0025 | 0.0113 | 0.0152 | 0.0565 | 0.0539 | 0.0774 | 0.0786 | 0.0493 | 0.0607 | 0.0870 | 0.0851 | 0.7156 | 0.7027 | 0.0007 | 0.0000 | 0.0020 | 0.0119 | 0.0543 | 0.0701 | 0.0508 | 0.0795 | 0.7308 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 465 | 643 | 8720 | 12380 | 327.7 | 56.71 | 178.47 | 263.33 | 253 | 288 | 306 | 320 | 333 | 346 | 358 | 371 | 394 | 0.0826 | 1023 | 1.053 | 189.34 | 55.01 | 1 | 0.0515 | 449 | 0.0016 | 19.71 | 6.739 | 0.2552 | 110617.0 | 38300000 | 13500000000 | 4860000000000 | 0.4132 | 0.2316 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0010 | 0.0001 | 0.0059 | 0.0010 | 0.0246 | 0.0101 | 0.0541 | 0.0199 | 0.0557 | 0.0130 | 0.0950 | 0.0226 | 0.7636 | 0.9332 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0001 | 0.0030 | 0.0009 | 0.0126 | 0.0096 | 0.0228 | 0.0178 | 0.0228 | 0.0096 | 0.0370 | 0.0162 | 0.9017 | 0.9456 | 0.0114 | 0.0000 | 0.0227 | 0.0000 | 0.0272 | 0.0000 | 0.0681 | 0.0000 | 0.0988 | 0.0000 | 0.1703 | 0.0000 | 0.1067 | 0.0000 | 0.1226 | 0.0000 | 0.3723 | 0.0000 | 0.0008 | 0.0019 | 0.0071 | 0.0173 | 0.0483 | 0.0854 | 0.0861 | 0.1201 | 0.6330 | 18 | 25 | 36 | 52 | 72 | 98 | 148 | 262 | 503 | 0.0250 | 35.86 | 5.284 | 0.5431 | 101188.0 | 92200000 | 104000000000 | 133000000000000 | 0.5504 | 0.1103 | 0.0118 | 0.0028 | 0.0634 | 0.0052 | 0.1160 | 0.0282 | 0.1461 | 0.0612 | 0.1912 | 0.1266 | 0.1751 | 0.1507 | 0.1224 | 0.1351 | 0.0988 | 0.1573 | 0.0752 | 0.3329 | 0.0005 | 0.0002 | 0.0003 | 0.0011 | 0.0024 | 0.0023 | 0.0079 | 0.0094 | 0.0482 | 0.0428 | 0.0854 | 0.0656 | 0.0514 | 0.0563 | 0.0801 | 0.0808 | 0.7238 | 0.7415 | 0.0000 | 0.0000 | 0.0021 | 0.0008 | 0.0042 | 0.0035 | 0.0101 | 0.0097 | 0.0538 | 0.0635 | 0.0894 | 0.0884 | 0.0594 | 0.0666 | 0.0876 | 0.0970 | 0.6934 | 0.6706 | 0.0000 | 0.0003 | 0.0031 | 0.0089 | 0.0520 | 0.0851 | 0.0560 | 0.0875 | 0.7072 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 400 | 407 | 6276 | 11399 | 375.7 | 86.02 | 140.41 | 164.45 | 245 | 323 | 357 | 378 | 396 | 413 | 428 | 444 | 463 | 0.0798 | 910 | 1.138 | 23.43 | 8.49 | 5 | 0.0099 | 62 | 0.0020 | 19.90 | 6.638 | 0.2782 | 148520.0 | 60600000 | 25300000000 | 10700000000000 | 0.3938 | 0.2401 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0021 | 0.0000 | 0.0137 | 0.0000 | 0.0354 | 0.0108 | 0.0722 | 0.0252 | 0.0748 | 0.0104 | 0.1107 | 0.0183 | 0.6891 | 0.9352 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0137 | 0.0108 | 0.0298 | 0.0252 | 0.0216 | 0.0104 | 0.0319 | 0.0169 | 0.9017 | 0.9367 | 0.0072 | 1.0000 | 0.0184 | 0.0000 | 0.0419 | 0.0000 | 0.0593 | 0.0000 | 0.0992 | 0.0000 | 0.1329 | 0.0000 | 0.1299 | 0.0000 | 0.1227 | 0.0000 | 0.3885 | 0.0000 | 0.0000 | 0.0010 | 0.0031 | 0.0067 | 0.0347 | 0.0601 | 0.0515 | 0.0772 | 0.7656 | 9 | 11 | 15 | 29 | 67 | 119 | 185 | 272 | 389 | 0.0593 | 7.25 | 4.451 | 0.5348 | 46754.1 | 20300000 | 10200000000 | 5650000000000 | 0.4511 | 0.1880 | 0.0237 | 0.0010 | 0.1225 | 0.0110 | 0.2381 | 0.0628 | 0.1729 | 0.1187 | 0.1275 | 0.1830 | 0.1265 | 0.1945 | 0.0810 | 0.1237 | 0.0632 | 0.1062 | 0.0445 | 0.1990 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0017 | 0.0009 | 0.0089 | 0.0072 | 0.0450 | 0.0402 | 0.0820 | 0.0693 | 0.0542 | 0.0504 | 0.0858 | 0.0775 | 0.7214 | 0.7543 | 0.0003 | 0.0003 | 0.0030 | 0.0015 | 0.0041 | 0.0034 | 0.0160 | 0.0153 | 0.0574 | 0.0644 | 0.0907 | 0.1103 | 0.0655 | 0.0754 | 0.1045 | 0.1051 | 0.6586 | 0.6243 | 0.0002 | 0.0002 | 0.0019 | 0.0112 | 0.0594 | 0.0827 | 0.0622 | 0.0946 | 0.6875 | |
MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 911 | 863 | 3384 | 11761 | 420.9 | 86.47 | 4.73 | 2.08 | 302 | 339 | 369 | 396 | 423 | 445 | 469 | 496 | 541 | 0.0709 | 834 | 1.119 | 147.57 | 40.85 | 2 | 0.0999 | 338 | 0.0022 | 9.37 | 6.372 | 0.3153 | 184655.0 | 84100000 | 39600000000 | 19200000000000 | 0.4075 | 0.2262 | 0.0000 | 0.0000 | 0.0009 | 0.0003 | 0.0028 | 0.0009 | 0.0122 | 0.0018 | 0.0380 | 0.0163 | 0.0576 | 0.0317 | 0.0595 | 0.0211 | 0.0792 | 0.0350 | 0.7498 | 0.8928 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0044 | 0.0012 | 0.0176 | 0.0145 | 0.0223 | 0.0252 | 0.0223 | 0.0145 | 0.0318 | 0.0228 | 0.9012 | 0.9217 | 0.0017 | 0.0164 | 0.0067 | 0.0820 | 0.0151 | 0.1148 | 0.0334 | 0.0656 | 0.0552 | 0.1475 | 0.0970 | 0.1967 | 0.0719 | 0.0984 | 0.1070 | 0.1148 | 0.6120 | 0.1639 | 0.0006 | 0.0006 | 0.0041 | 0.0122 | 0.0232 | 0.0313 | 0.0481 | 0.0614 | 0.8188 | 3 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 8 | 0.1884 | 0.49 | 1.040 | 0.5055 | 26.7 | 168.516 | 1167.32 | 8724.82 | 0.5573 | 0.1272 | 0.0310 | 0.0008 | 0.1092 | 0.0058 | 0.1823 | 0.0231 | 0.2315 | 0.0675 | 0.2131 | 0.1372 | 0.1494 | 0.2192 | 0.0658 | 0.2642 | 0.0165 | 0.2065 | 0.0011 | 0.0758 | 0.0004 | 0.0000 | 0.0062 | 0.0001 | 0.0262 | 0.0023 | 0.0677 | 0.0103 | 0.1256 | 0.0273 | 0.1932 | 0.0570 | 0.2350 | 0.1221 | 0.2198 | 0.2928 | 0.1259 | 0.4881 | 0.0687 | 0.1947 | 0.1761 | 0.2643 | 0.2285 | 0.2297 | 0.2191 | 0.1457 | 0.1708 | 0.0988 | 0.0955 | 0.0490 | 0.0325 | 0.0152 | 0.0079 | 0.0021 | 0.0008 | 0.0004 | 0.0121 | 0.0572 | 0.1283 | 0.1756 | 0.2122 | 0.1867 | 0.1313 | 0.0730 | 0.0235 | |||
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 387 | 777 | 3566 | 6931 | 639.4 | 107.04 | 10.06 | 4.66 | 486 | 547 | 588 | 620 | 651 | 674 | 700 | 732 | 773 | 0.0884 | 613 | 1.124 | 98.72 | 31.38 | 1 | 0.0670 | 239 | 0.0010 | 36.61 | 7.121 | 0.1989 | 420338.0 | 283000000 | 195000000000 | 137000000000000 | 0.3984 | 0.2382 | 0.0011 | 0.0000 | 0.0011 | 0.0000 | 0.0053 | 0.0000 | 0.0083 | 0.0003 | 0.0320 | 0.0164 | 0.0531 | 0.0288 | 0.0531 | 0.0164 | 0.0753 | 0.0257 | 0.7708 | 0.9124 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0029 | 0.0003 | 0.0186 | 0.0158 | 0.0258 | 0.0270 | 0.0225 | 0.0141 | 0.0287 | 0.0217 | 0.9000 | 0.9211 | 0.0000 | 0.0000 | 0.0149 | 0.1667 | 0.0446 | 0.0833 | 0.0718 | 0.2500 | 0.0767 | 0.2500 | 0.1287 | 0.2500 | 0.0965 | 0.0000 | 0.1658 | 0.0000 | 0.4010 | 0.0000 | 0.0010 | 0.0005 | 0.0021 | 0.0124 | 0.0361 | 0.0465 | 0.0589 | 0.0780 | 0.7646 | 5 | 7 | 7 | 8 | 9 | 10 | 12 | 13 | 16 | 0.4127 | 0.30 | 1.079 | 0.7896 | 122.9 | 1790.87 | 30353.2 | 582290 | 0.5361 | 0.1291 | 0.0335 | 0.0045 | 0.0959 | 0.0139 | 0.1633 | 0.0252 | 0.2000 | 0.0536 | 0.2138 | 0.0902 | 0.1661 | 0.1532 | 0.0951 | 0.2086 | 0.0264 | 0.2648 | 0.0059 | 0.1859 | 0.0097 | 0.0003 | 0.0311 | 0.0027 | 0.0593 | 0.0058 | 0.0757 | 0.0236 | 0.0929 | 0.0587 | 0.1048 | 0.1040 | 0.1018 | 0.1321 | 0.1193 | 0.1860 | 0.4054 | 0.4869 | 0.0652 | 0.0615 | 0.0666 | 0.0608 | 0.0576 | 0.0615 | 0.0566 | 0.0660 | 0.0756 | 0.0801 | 0.0809 | 0.1008 | 0.0856 | 0.1127 | 0.1365 | 0.1579 | 0.3754 | 0.2987 | 0.0501 | 0.0714 | 0.0772 | 0.0740 | 0.0778 | 0.0730 | 0.0804 | 0.1126 | 0.3836 | |||
SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 949 | 628 | 5444 | 5921 | 503.2 | 113.35 | 118.69 | 220.33 | 340 | 443 | 485 | 510 | 528 | 546 | 564 | 585 | 614 | 0.1099 | 651 | 1.294 | 20.22 | 8.60 | 1 | 0.0103 | 56 | 0.0029 | 17.80 | 6.312 | 0.3065 | 266047.0 | 145000000 | 80700000000 | 45600000000000 | 0.4084 | 0.2255 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0074 | 0.0008 | 0.0372 | 0.0133 | 0.0597 | 0.0230 | 0.0638 | 0.0153 | 0.1089 | 0.0266 | 0.7193 | 0.9208 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0004 | 0.0158 | 0.0130 | 0.0270 | 0.0200 | 0.0203 | 0.0120 | 0.0363 | 0.0200 | 0.8999 | 0.9346 | 0.0097 | 0.0000 | 0.0110 | 0.0789 | 0.0331 | 0.1579 | 0.0607 | 0.0789 | 0.1062 | 0.1842 | 0.1407 | 0.1053 | 0.1407 | 0.0789 | 0.1434 | 0.2105 | 0.3545 | 0.1053 | 0.0000 | 0.0009 | 0.0035 | 0.0087 | 0.0363 | 0.0603 | 0.0609 | 0.0873 | 0.7421 | 7 | 10 | 14 | 19 | 25 | 37 | 74 | 153 | 375 | 0.0775 | 22.34 | 4.056 | 0.5583 | 62626.7 | 51300000 | 50500000000 | 55700000000000 | 0.5274 | 0.1314 | 0.0603 | 0.0015 | 0.2190 | 0.0164 | 0.3175 | 0.0848 | 0.1429 | 0.1711 | 0.1524 | 0.2321 | 0.0603 | 0.2292 | 0.0222 | 0.1295 | 0.0159 | 0.0744 | 0.0095 | 0.0610 | 0.0013 | 0.0006 | 0.0051 | 0.0011 | 0.0019 | 0.0033 | 0.0103 | 0.0094 | 0.0994 | 0.0833 | 0.1186 | 0.1127 | 0.0962 | 0.0944 | 0.1237 | 0.1133 | 0.5436 | 0.5819 | 0.0000 | 0.0009 | 0.0016 | 0.0009 | 0.0072 | 0.0071 | 0.0177 | 0.0301 | 0.1157 | 0.1125 | 0.1301 | 0.1364 | 0.1028 | 0.0912 | 0.1205 | 0.1355 | 0.5044 | 0.4854 | 0.0007 | 0.0007 | 0.0036 | 0.0144 | 0.1114 | 0.1222 | 0.0978 | 0.1258 | 0.5234 | |||
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 592 | 492 | 4236 | 12697 | 651.9 | 140.09 | 147.12 | 254.46 | 443 | 556 | 603 | 639 | 676 | 704 | 732 | 763 | 805 | 0.0784 | 995 | 1.202 | 120.07 | 45.18 | 3 | 0.0708 | 300 | 0.0015 | 22.93 | 6.808 | 0.2599 | 444572.0 | 313000000 | 227000000000 | 168000000000000 | 0.4044 | 0.2398 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0034 | 0.0003 | 0.0058 | 0.0021 | 0.0378 | 0.0206 | 0.0903 | 0.0398 | 0.0701 | 0.0247 | 0.1192 | 0.0367 | 0.6731 | 0.8759 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0003 | 0.0006 | 0.0013 | 0.0152 | 0.0187 | 0.0336 | 0.0329 | 0.0175 | 0.0152 | 0.0336 | 0.0255 | 0.8987 | 0.9062 | 0.0079 | 0.0000 | 0.0111 | 0.0154 | 0.0300 | 0.1385 | 0.0679 | 0.1385 | 0.1153 | 0.2308 | 0.1801 | 0.1846 | 0.1153 | 0.1385 | 0.1485 | 0.1231 | 0.3239 | 0.0308 | 0.0000 | 0.0017 | 0.0033 | 0.0079 | 0.0426 | 0.0857 | 0.0662 | 0.0919 | 0.7007 | 8 | 9 | 11 | 14 | 20 | 38 | 105 | 241 | 506 | 0.1619 | 33.70 | 4.314 | 0.6111 | 86390.9 | 71500000 | 69700000000 | 75500000000000 | 0.6018 | 0.0757 | 0.0644 | 0.0043 | 0.2356 | 0.0325 | 0.2932 | 0.1702 | 0.1458 | 0.1856 | 0.1136 | 0.2002 | 0.0661 | 0.1856 | 0.0373 | 0.0821 | 0.0305 | 0.0736 | 0.0136 | 0.0659 | 0.0000 | 0.0003 | 0.0014 | 0.0000 | 0.0005 | 0.0025 | 0.0096 | 0.0093 | 0.0536 | 0.0496 | 0.1026 | 0.0981 | 0.0517 | 0.0496 | 0.0780 | 0.0733 | 0.7027 | 0.7174 | 0.0003 | 0.0007 | 0.0013 | 0.0004 | 0.0023 | 0.0011 | 0.0134 | 0.0173 | 0.0623 | 0.0665 | 0.1086 | 0.1122 | 0.0633 | 0.0725 | 0.0939 | 0.0952 | 0.6546 | 0.6341 | 0.0000 | 0.0012 | 0.0024 | 0.0150 | 0.0559 | 0.1057 | 0.0574 | 0.0811 | 0.6813 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 665 | 315 | 3881 | 7921 | 606.2 | 94.41 | 68.43 | 170.19 | 472 | 541 | 568 | 588 | 606 | 629 | 660 | 694 | 726 | 0.0917 | 726 | 0.976 | 112.07 | 42.38 | 2 | 0.0825 | 320 | 0.0014 | 32.18 | 6.910 | 0.2353 | 376420.0 | 239000000 | 154000000000 | 101000000000000 | 0.4392 | 0.1933 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0052 | 0.0005 | 0.0345 | 0.0169 | 0.0495 | 0.0301 | 0.0505 | 0.0161 | 0.0697 | 0.0270 | 0.7890 | 0.9095 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0005 | 0.0212 | 0.0169 | 0.0256 | 0.0301 | 0.0206 | 0.0161 | 0.0317 | 0.0270 | 0.8986 | 0.9095 | 0.0054 | 0.0000 | 0.0161 | 0.0000 | 0.0215 | 0.0000 | 0.0538 | 0.0000 | 0.1048 | 0.0000 | 0.1532 | 0.0000 | 0.1183 | 0.0000 | 0.1263 | 0.0000 | 0.4005 | 0.0000 | 0.0031 | 0.0031 | 0.0097 | 0.0219 | 0.0429 | 0.0566 | 0.0536 | 0.0929 | 0.7163 | 5 | 6 | 7 | 9 | 10 | 11 | 14 | 30 | 209 | 0.1903 | 6.63 | 2.602 | 0.6219 | 33642.3 | 23500000 | 18600000000 | 16100000000000 | 0.5469 | 0.1234 | 0.0143 | 0.0118 | 0.2071 | 0.0059 | 0.2500 | 0.0710 | 0.2357 | 0.1154 | 0.2571 | 0.2308 | 0.0286 | 0.2337 | 0.0071 | 0.1834 | 0.0000 | 0.1065 | 0.0000 | 0.0414 | 0.0000 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0050 | 0.0119 | 0.0114 | 0.0500 | 0.0456 | 0.0738 | 0.0777 | 0.0484 | 0.0428 | 0.0745 | 0.0720 | 0.7407 | 0.7418 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0009 | 0.0089 | 0.0132 | 0.0526 | 0.0545 | 0.0847 | 0.0771 | 0.0455 | 0.0526 | 0.0794 | 0.0808 | 0.7279 | 0.7209 | 0.0000 | 0.0000 | 0.0017 | 0.0093 | 0.0499 | 0.0854 | 0.0448 | 0.0761 | 0.7327 | |||
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 149 | 240 | 6671 | 12334 | 390.0 | 50.74 | 109.56 | 270.04 | 317 | 352 | 374 | 389 | 399 | 409 | 419 | 431 | 446 | 0.0712 | 878 | 0.700 | 125.40 | 29.61 | 3 | 0.0475 | 317 | 0.0019 | 22.81 | 6.624 | 0.2349 | 154695.0 | 62200000 | 25300000000 | 10400000000000 | 0.4580 | 0.1948 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0037 | 0.0003 | 0.0169 | 0.0112 | 0.0407 | 0.0210 | 0.0412 | 0.0134 | 0.0715 | 0.0187 | 0.8249 | 0.9354 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0023 | 0.0003 | 0.0133 | 0.0112 | 0.0316 | 0.0210 | 0.0235 | 0.0134 | 0.0319 | 0.0187 | 0.8969 | 0.9354 | 0.1176 | 0.0000 | 0.1438 | 0.0000 | 0.1373 | 0.0000 | 0.1830 | 0.0000 | 0.1111 | 0.0000 | 0.1569 | 0.0000 | 0.0261 | 0.0000 | 0.0523 | 0.0000 | 0.0719 | 0.0000 | 0.0020 | 0.0033 | 0.0091 | 0.0202 | 0.0463 | 0.0663 | 0.0825 | 0.1189 | 0.6514 | 9 | 11 | 12 | 14 | 15 | 18 | 24 | 59 | 344 | 0.2142 | 6.81 | 2.736 | 0.6641 | 84919.1 | 101000000 | 144000000000 | 229000000000000 | 0.5929 | 0.1077 | 0.0204 | 0.0068 | 0.0980 | 0.0068 | 0.1592 | 0.0492 | 0.1878 | 0.0881 | 0.2082 | 0.1593 | 0.1755 | 0.1864 | 0.1020 | 0.1203 | 0.0367 | 0.1661 | 0.0122 | 0.2169 | 0.0005 | 0.0017 | 0.0019 | 0.0004 | 0.0014 | 0.0034 | 0.0052 | 0.0085 | 0.0331 | 0.0296 | 0.0553 | 0.0525 | 0.0355 | 0.0407 | 0.0766 | 0.0805 | 0.7905 | 0.7827 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0021 | 0.0017 | 0.0064 | 0.0079 | 0.0380 | 0.0350 | 0.0545 | 0.0599 | 0.0401 | 0.0418 | 0.0866 | 0.0870 | 0.7722 | 0.7662 | 0.0000 | 0.0000 | 0.0020 | 0.0076 | 0.0289 | 0.0613 | 0.0370 | 0.0770 | 0.7863 | |
SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 451 | 11232 | 18145 | 198.9 | 80.62 | 6.13 | 2.92 | 96 | 118 | 138 | 163 | 190 | 224 | 254 | 281 | 308 | 0.0881 | 1598 | 0.402 | 135.09 | 20.03 | 6 | 0.0363 | 408 | 0.0017 | 7.54 | 6.630 | 0.3605 | 46068.3 | 11900000 | 3280000000 | 953000000000 | 0.4257 | 0.1921 | 0.0034 | 0.0015 | 0.0058 | 0.0030 | 0.0089 | 0.0074 | 0.0294 | 0.0164 | 0.0684 | 0.0406 | 0.1042 | 0.0619 | 0.1097 | 0.0584 | 0.1415 | 0.0780 | 0.5287 | 0.7328 | 0.0006 | 0.0003 | 0.0010 | 0.0001 | 0.0022 | 0.0029 | 0.0064 | 0.0067 | 0.0146 | 0.0168 | 0.0254 | 0.0283 | 0.0235 | 0.0230 | 0.0296 | 0.0320 | 0.8967 | 0.8898 | 0.0005 | 0.0025 | 0.0033 | 0.0051 | 0.0060 | 0.0132 | 0.0098 | 0.0229 | 0.0280 | 0.0467 | 0.0282 | 0.0642 | 0.0358 | 0.0778 | 0.0499 | 0.0999 | 0.8385 | 0.6677 | 0.0009 | 0.0007 | 0.0024 | 0.0073 | 0.0189 | 0.0239 | 0.0284 | 0.0375 | 0.8799 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.1305 | 0.44 | 1.002 | 0.4054 | 46.1 | 458.785 | 7687.85 | 234458 | 0.5483 | 0.1268 | 0.0123 | 0.0015 | 0.0555 | 0.0107 | 0.1399 | 0.0297 | 0.2151 | 0.0734 | 0.2476 | 0.1533 | 0.1919 | 0.2308 | 0.1031 | 0.2579 | 0.0306 | 0.1797 | 0.0042 | 0.0631 | 0.0008 | 0.0001 | 0.0083 | 0.0014 | 0.0270 | 0.0074 | 0.0633 | 0.0263 | 0.1189 | 0.0658 | 0.1643 | 0.1156 | 0.2017 | 0.2003 | 0.2201 | 0.2840 | 0.1956 | 0.2992 | 0.1197 | 0.2233 | 0.1816 | 0.2100 | 0.1733 | 0.1903 | 0.1579 | 0.1256 | 0.1231 | 0.0803 | 0.0916 | 0.0538 | 0.0625 | 0.0439 | 0.0525 | 0.0381 | 0.0379 | 0.0347 | 0.0066 | 0.0454 | 0.0962 | 0.1383 | 0.1787 | 0.1873 | 0.1512 | 0.1164 | 0.0797 | |
MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 187 | 499 | 5159 | 11813 | 530.2 | 150.73 | 46.53 | 99.31 | 336 | 405 | 473 | 515 | 555 | 600 | 635 | 664 | 696 | 0.0781 | 923 | 1.105 | 73.82 | 25.55 | 4 | 0.0382 | 197 | 0.0006 | 44.92 | 7.570 | 0.1925 | 303806.0 | 182000000 | 112000000000 | 70800000000000 | 0.3690 | 0.2568 | 0.0020 | 0.0000 | 0.0029 | 0.0000 | 0.0069 | 0.0004 | 0.0167 | 0.0024 | 0.0587 | 0.0163 | 0.0953 | 0.0308 | 0.0843 | 0.0238 | 0.1059 | 0.0400 | 0.6273 | 0.8863 | 0.0005 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0025 | 0.0021 | 0.0185 | 0.0146 | 0.0285 | 0.0275 | 0.0217 | 0.0173 | 0.0307 | 0.0266 | 0.8966 | 0.9119 | 0.0019 | 0.0635 | 0.0052 | 0.0476 | 0.0110 | 0.1270 | 0.0213 | 0.1429 | 0.0549 | 0.0635 | 0.0614 | 0.1270 | 0.0627 | 0.0952 | 0.1008 | 0.1270 | 0.6807 | 0.2063 | 0.0010 | 0.0024 | 0.0038 | 0.0076 | 0.0244 | 0.0344 | 0.0337 | 0.0485 | 0.8443 | 6 | 8 | 9 | 10 | 11 | 13 | 17 | 52 | 137 | 0.1781 | 7.69 | 3.150 | 0.7073 | 12026.7 | 6360000 | 4770000000 | 4300000000000 | 0.4827 | 0.1912 | 0.0208 | 0.0043 | 0.0655 | 0.0157 | 0.1042 | 0.0386 | 0.1548 | 0.0815 | 0.1935 | 0.1302 | 0.1905 | 0.1774 | 0.1488 | 0.1245 | 0.0893 | 0.1660 | 0.0327 | 0.2618 | 0.0004 | 0.0007 | 0.0004 | 0.0018 | 0.0011 | 0.0036 | 0.0042 | 0.0075 | 0.0229 | 0.0220 | 0.0362 | 0.0341 | 0.0320 | 0.0242 | 0.0526 | 0.0512 | 0.8502 | 0.8550 | 0.0000 | 0.0000 | 0.0022 | 0.0019 | 0.0044 | 0.0033 | 0.0079 | 0.0071 | 0.0271 | 0.0288 | 0.0411 | 0.0506 | 0.0389 | 0.0378 | 0.0599 | 0.0624 | 0.8186 | 0.8080 | 0.0000 | 0.0012 | 0.0032 | 0.0085 | 0.0263 | 0.0388 | 0.0324 | 0.0599 | 0.8297 | |
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 182 | 324 | 4862 | 8847 | 382.1 | 46.56 | 84.31 | 223.89 | 321 | 348 | 363 | 376 | 385 | 395 | 406 | 419 | 440 | 0.0849 | 751 | 0.869 | 141.40 | 42.45 | 2 | 0.0755 | 367 | 0.0020 | 27.89 | 6.580 | 0.2423 | 148135.0 | 58200000 | 23200000000 | 9310000000000 | 0.4327 | 0.2087 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0044 | 0.0000 | 0.0215 | 0.0134 | 0.0430 | 0.0245 | 0.0423 | 0.0117 | 0.0642 | 0.0210 | 0.8233 | 0.9294 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0153 | 0.0134 | 0.0306 | 0.0245 | 0.0237 | 0.0117 | 0.0317 | 0.0210 | 0.8966 | 0.9294 | 0.0214 | 0.0000 | 0.0856 | 0.0000 | 0.1016 | 0.0000 | 0.1283 | 0.0000 | 0.1176 | 0.0000 | 0.1444 | 0.0000 | 0.1016 | 0.0000 | 0.1123 | 0.0000 | 0.1872 | 0.0000 | 0.0019 | 0.0049 | 0.0106 | 0.0314 | 0.0538 | 0.0947 | 0.0981 | 0.1163 | 0.5883 | 8 | 9 | 11 | 12 | 13 | 15 | 20 | 43 | 199 | 0.1434 | 6.44 | 2.531 | 0.5616 | 57228.9 | 60400000 | 73600000000 | 96900000000000 | 0.7057 | 0.0462 | 0.0466 | 0.0000 | 0.0975 | 0.0157 | 0.2458 | 0.0747 | 0.1144 | 0.1041 | 0.1653 | 0.1434 | 0.1483 | 0.1945 | 0.1102 | 0.1611 | 0.0466 | 0.1336 | 0.0254 | 0.1729 | 0.0007 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0048 | 0.0144 | 0.0133 | 0.0390 | 0.0387 | 0.0787 | 0.0678 | 0.0568 | 0.0599 | 0.1026 | 0.0998 | 0.7066 | 0.7145 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0016 | 0.0009 | 0.0122 | 0.0192 | 0.0636 | 0.0603 | 0.0865 | 0.0857 | 0.0530 | 0.0594 | 0.1117 | 0.0970 | 0.6713 | 0.6740 | 0.0000 | 0.0008 | 0.0023 | 0.0129 | 0.0530 | 0.0802 | 0.0560 | 0.1104 | 0.6846 | |
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 886 | 459 | 3618 | 10342 | 579.4 | 120.00 | 16.41 | 14.61 | 402 | 502 | 541 | 570 | 596 | 621 | 644 | 667 | 707 | 0.0617 | 638 | 0.872 | 72.47 | 21.02 | 4 | 0.0506 | 183 | 0.0010 | 57.19 | 7.152 | 0.1994 | 350122.0 | 218000000 | 140000000000 | 91900000000000 | 0.4429 | 0.2126 | 0.0004 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0006 | 0.0086 | 0.0012 | 0.0409 | 0.0173 | 0.0601 | 0.0352 | 0.0530 | 0.0212 | 0.0823 | 0.0391 | 0.7539 | 0.8852 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0013 | 0.0009 | 0.0167 | 0.0167 | 0.0279 | 0.0301 | 0.0196 | 0.0140 | 0.0382 | 0.0289 | 0.8963 | 0.9084 | 0.0088 | 0.0000 | 0.0044 | 0.0980 | 0.0199 | 0.0000 | 0.0508 | 0.0980 | 0.1258 | 0.1569 | 0.1523 | 0.1765 | 0.1192 | 0.0588 | 0.1501 | 0.1373 | 0.3687 | 0.2745 | 0.0000 | 0.0005 | 0.0063 | 0.0146 | 0.0466 | 0.0777 | 0.0670 | 0.0869 | 0.7005 | 6 | 8 | 9 | 11 | 13 | 15 | 17 | 20 | 29 | 0.2798 | 0.41 | 1.932 | 0.8610 | 482.7 | 28156.6 | 2820000 | 388000000 | 0.4309 | 0.2072 | 0.0435 | 0.0205 | 0.0470 | 0.0372 | 0.0509 | 0.0455 | 0.0895 | 0.0516 | 0.1126 | 0.0612 | 0.1545 | 0.0846 | 0.2073 | 0.1008 | 0.1905 | 0.1706 | 0.1043 | 0.4280 | 0.0225 | 0.0151 | 0.0206 | 0.0257 | 0.0213 | 0.0301 | 0.0324 | 0.0319 | 0.0506 | 0.0421 | 0.0689 | 0.0635 | 0.0845 | 0.0648 | 0.1386 | 0.1026 | 0.5606 | 0.6242 | 0.0382 | 0.0267 | 0.0326 | 0.0130 | 0.0336 | 0.0298 | 0.0424 | 0.0360 | 0.0559 | 0.0477 | 0.0634 | 0.0701 | 0.0662 | 0.0775 | 0.1058 | 0.0967 | 0.5620 | 0.6026 | 0.0209 | 0.0300 | 0.0386 | 0.0551 | 0.0695 | 0.0973 | 0.0921 | 0.1086 | 0.4879 | |
SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1170 | 829 | 5625 | 11492 | 469.5 | 111.56 | 192.86 | 189.26 | 337 | 410 | 439 | 458 | 475 | 495 | 522 | 556 | 596 | 0.0699 | 803 | 0.905 | 84.12 | 26.57 | 4 | 0.0398 | 224 | 0.0027 | 17.91 | 6.386 | 0.3047 | 232826.0 | 120000000 | 63700000000 | 34800000000000 | 0.4179 | 0.2125 | 0.0008 | 0.0000 | 0.0003 | 0.0000 | 0.0023 | 0.0000 | 0.0132 | 0.0004 | 0.0347 | 0.0157 | 0.0700 | 0.0305 | 0.0692 | 0.0190 | 0.0975 | 0.0353 | 0.7120 | 0.8991 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0140 | 0.0121 | 0.0255 | 0.0227 | 0.0261 | 0.0113 | 0.0364 | 0.0204 | 0.8962 | 0.9335 | 0.0030 | 0.0128 | 0.0080 | 0.0064 | 0.0189 | 0.0321 | 0.0427 | 0.0641 | 0.0895 | 0.1154 | 0.1123 | 0.2051 | 0.1203 | 0.1090 | 0.1252 | 0.1474 | 0.4801 | 0.3077 | 0.0023 | 0.0030 | 0.0056 | 0.0251 | 0.0422 | 0.0700 | 0.0812 | 0.0888 | 0.6818 | 7 | 11 | 32 | 83 | 150 | 207 | 272 | 351 | 468 | 0.0155 | 17.10 | 5.622 | 0.3721 | 73008.9 | 34800000 | 19300000000 | 12000000000000 | 0.4101 | 0.2114 | 0.0192 | 0.0004 | 0.1141 | 0.0067 | 0.2050 | 0.0445 | 0.1566 | 0.1012 | 0.1559 | 0.1709 | 0.1533 | 0.2112 | 0.0922 | 0.1401 | 0.0591 | 0.1257 | 0.0445 | 0.1993 | 0.0002 | 0.0000 | 0.0007 | 0.0006 | 0.0014 | 0.0008 | 0.0078 | 0.0063 | 0.0471 | 0.0404 | 0.0894 | 0.0708 | 0.0685 | 0.0552 | 0.0980 | 0.0723 | 0.6870 | 0.7536 | 0.0000 | 0.0003 | 0.0034 | 0.0029 | 0.0058 | 0.0081 | 0.0171 | 0.0318 | 0.0772 | 0.0837 | 0.1322 | 0.1470 | 0.0849 | 0.1040 | 0.1207 | 0.1132 | 0.5586 | 0.5091 | 0.0004 | 0.0012 | 0.0039 | 0.0173 | 0.0618 | 0.1044 | 0.0853 | 0.1164 | 0.6093 | |||
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 259 | 595 | 3281 | 8845 | 537.2 | 98.78 | 47.70 | 69.98 | 406 | 455 | 487 | 513 | 535 | 555 | 578 | 608 | 681 | 0.0684 | 605 | 1.005 | 109.84 | 37.48 | 2 | 0.0884 | 290 | 0.0012 | 24.77 | 6.942 | 0.2330 | 298323.0 | 171000000 | 101000000000 | 61500000000000 | 0.4559 | 0.1915 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0006 | 0.0295 | 0.0159 | 0.0565 | 0.0312 | 0.0510 | 0.0243 | 0.0674 | 0.0328 | 0.7880 | 0.8952 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0006 | 0.0159 | 0.0128 | 0.0297 | 0.0253 | 0.0244 | 0.0131 | 0.0304 | 0.0186 | 0.8956 | 0.9295 | 0.0066 | 0.0137 | 0.0088 | 0.0274 | 0.0243 | 0.0959 | 0.0133 | 0.0959 | 0.0575 | 0.2055 | 0.0973 | 0.1507 | 0.0619 | 0.1096 | 0.0841 | 0.1507 | 0.6460 | 0.1507 | 0.0012 | 0.0000 | 0.0025 | 0.0204 | 0.0532 | 0.0835 | 0.0884 | 0.1070 | 0.6438 | 8 | 9 | 11 | 12 | 14 | 19 | 46 | 78 | 131 | 0.2066 | 2.60 | 3.143 | 0.7617 | 7171.8 | 1810000 | 603000000 | 239000000000 | 0.5155 | 0.1378 | 0.0352 | 0.0029 | 0.0580 | 0.0155 | 0.0890 | 0.0638 | 0.1201 | 0.0629 | 0.1532 | 0.0977 | 0.1636 | 0.1460 | 0.1822 | 0.1199 | 0.1387 | 0.1586 | 0.0600 | 0.3327 | 0.0007 | 0.0007 | 0.0014 | 0.0020 | 0.0021 | 0.0029 | 0.0064 | 0.0085 | 0.0152 | 0.0186 | 0.0258 | 0.0232 | 0.0237 | 0.0235 | 0.0488 | 0.0405 | 0.8759 | 0.8803 | 0.0017 | 0.0015 | 0.0009 | 0.0039 | 0.0064 | 0.0064 | 0.0111 | 0.0148 | 0.0273 | 0.0261 | 0.0413 | 0.0542 | 0.0388 | 0.0473 | 0.0725 | 0.0719 | 0.8001 | 0.7740 | 0.0008 | 0.0008 | 0.0035 | 0.0096 | 0.0207 | 0.0261 | 0.0337 | 0.0560 | 0.8489 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 141 | 699 | 7154 | 15239 | 575.9 | 95.31 | 29.74 | 48.68 | 449 | 502 | 533 | 558 | 579 | 601 | 622 | 652 | 696 | 0.0671 | 1023 | 0.931 | 90.61 | 28.60 | 3 | 0.0352 | 252 | 0.0011 | 31.86 | 7.150 | 0.2308 | 340741.0 | 207000000 | 128000000000 | 80800000000000 | 0.4150 | 0.2161 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0061 | 0.0006 | 0.0245 | 0.0127 | 0.0495 | 0.0227 | 0.0463 | 0.0142 | 0.0702 | 0.0222 | 0.8014 | 0.9276 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0025 | 0.0003 | 0.0155 | 0.0122 | 0.0287 | 0.0212 | 0.0234 | 0.0112 | 0.0340 | 0.0164 | 0.8955 | 0.9387 | 0.0066 | 0.0313 | 0.0131 | 0.1875 | 0.0210 | 0.0938 | 0.0329 | 0.1250 | 0.0631 | 0.1875 | 0.0972 | 0.1250 | 0.0907 | 0.0938 | 0.1196 | 0.1250 | 0.5558 | 0.0313 | 0.0011 | 0.0046 | 0.0060 | 0.0179 | 0.0447 | 0.0660 | 0.0690 | 0.0842 | 0.7066 | 6 | 8 | 9 | 10 | 12 | 15 | 21 | 33 | 71 | 0.1972 | 1.48 | 2.529 | 0.7147 | 3254.2 | 656547 | 165000000 | 46700000000 | 0.5056 | 0.1413 | 0.0414 | 0.0294 | 0.0670 | 0.0284 | 0.1535 | 0.0479 | 0.1859 | 0.0812 | 0.1934 | 0.1171 | 0.1618 | 0.1309 | 0.1106 | 0.1486 | 0.0640 | 0.2072 | 0.0226 | 0.2093 | 0.0062 | 0.0147 | 0.0081 | 0.0103 | 0.0180 | 0.0156 | 0.0240 | 0.0182 | 0.0531 | 0.0425 | 0.0837 | 0.0718 | 0.0721 | 0.0609 | 0.0963 | 0.1079 | 0.6385 | 0.6580 | 0.0031 | 0.0036 | 0.0076 | 0.0056 | 0.0132 | 0.0156 | 0.0287 | 0.0324 | 0.0651 | 0.0720 | 0.0970 | 0.0980 | 0.0707 | 0.0720 | 0.1050 | 0.1032 | 0.6096 | 0.5974 | 0.0052 | 0.0084 | 0.0102 | 0.0335 | 0.0664 | 0.0836 | 0.0740 | 0.0976 | 0.6210 | |||
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1109 | 467 | 7728 | 10985 | 187.4 | 61.96 | 106.16 | 170.18 | 109 | 128 | 147 | 169 | 186 | 203 | 220 | 239 | 268 | 0.0861 | 946 | 1.180 | 100.90 | 29.02 | 3 | 0.0294 | 227 | 0.0011 | 27.43 | 7.104 | 0.2644 | 38959.5 | 8810000 | 2140000000 | 549000000000 | 0.4404 | 0.1893 | 0.0019 | 0.0005 | 0.0066 | 0.0013 | 0.0109 | 0.0023 | 0.0241 | 0.0084 | 0.0675 | 0.0240 | 0.0947 | 0.0473 | 0.0944 | 0.0455 | 0.1310 | 0.0624 | 0.5688 | 0.8083 | 0.0006 | 0.0003 | 0.0015 | 0.0009 | 0.0032 | 0.0012 | 0.0043 | 0.0039 | 0.0171 | 0.0115 | 0.0221 | 0.0195 | 0.0225 | 0.0169 | 0.0332 | 0.0232 | 0.8955 | 0.9226 | 0.0028 | 0.0045 | 0.0052 | 0.0034 | 0.0131 | 0.0101 | 0.0197 | 0.0515 | 0.0553 | 0.1074 | 0.0933 | 0.1398 | 0.0778 | 0.1040 | 0.1172 | 0.1275 | 0.6157 | 0.4519 | 0.0003 | 0.0005 | 0.0034 | 0.0120 | 0.0330 | 0.0494 | 0.0546 | 0.0738 | 0.7730 | 10 | 13 | 16 | 20 | 29 | 52 | 97 | 156 | 295 | 0.0735 | 19.46 | 4.540 | 0.5815 | 40229.5 | 25000000 | 19500000000 | 17300000000000 | 0.4726 | 0.1847 | 0.0486 | 0.0029 | 0.0972 | 0.0161 | 0.1627 | 0.0732 | 0.1333 | 0.0992 | 0.1345 | 0.1522 | 0.1390 | 0.1690 | 0.0949 | 0.1107 | 0.0836 | 0.1148 | 0.1062 | 0.2618 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0042 | 0.0027 | 0.0152 | 0.0126 | 0.0576 | 0.0567 | 0.0829 | 0.0680 | 0.0576 | 0.0508 | 0.0880 | 0.0841 | 0.6936 | 0.7242 | 0.0007 | 0.0009 | 0.0045 | 0.0047 | 0.0064 | 0.0108 | 0.0288 | 0.0284 | 0.0804 | 0.0814 | 0.0932 | 0.1063 | 0.0718 | 0.0689 | 0.1044 | 0.1029 | 0.6098 | 0.5958 | 0.0003 | 0.0019 | 0.0055 | 0.0183 | 0.0685 | 0.0985 | 0.0711 | 0.1046 | 0.6313 | |||
MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1052 | 425 | 3025 | 6544 | 395.4 | 125.68 | 137.78 | 188.28 | 223 | 262 | 321 | 379 | 427 | 461 | 488 | 513 | 538 | 0.0767 | 502 | 0.961 | 105.32 | 29.00 | 2 | 0.0826 | 250 | 0.0010 | 36.99 | 7.117 | 0.2145 | 172122.0 | 79400000 | 38000000000 | 18700000000000 | 0.3829 | 0.2510 | 0.0000 | 0.0004 | 0.0066 | 0.0000 | 0.0094 | 0.0020 | 0.0169 | 0.0065 | 0.0778 | 0.0296 | 0.1321 | 0.0455 | 0.0965 | 0.0386 | 0.1781 | 0.0771 | 0.4827 | 0.8002 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0008 | 0.0014 | 0.0034 | 0.0182 | 0.0191 | 0.0383 | 0.0309 | 0.0163 | 0.0202 | 0.0299 | 0.0313 | 0.8954 | 0.8944 | 0.0019 | 0.0438 | 0.0028 | 0.0500 | 0.0112 | 0.0813 | 0.0168 | 0.0625 | 0.0493 | 0.1125 | 0.0503 | 0.1250 | 0.0615 | 0.1438 | 0.0829 | 0.1250 | 0.7235 | 0.2563 | 0.0000 | 0.0000 | 0.0012 | 0.0058 | 0.0226 | 0.0423 | 0.0359 | 0.0469 | 0.8454 | 11 | 15 | 21 | 35 | 61 | 94 | 140 | 217 | 376 | 0.0253 | 45.28 | 5.475 | 0.4795 | 54428.7 | 33000000 | 24600000000 | 20600000000000 | 0.5487 | 0.1238 | 0.0167 | 0.0007 | 0.0866 | 0.0051 | 0.1596 | 0.0425 | 0.1368 | 0.0717 | 0.1733 | 0.1281 | 0.1459 | 0.1801 | 0.1277 | 0.1274 | 0.0745 | 0.1384 | 0.0790 | 0.3060 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0017 | 0.0014 | 0.0118 | 0.0099 | 0.0557 | 0.0437 | 0.0861 | 0.0757 | 0.0621 | 0.0493 | 0.0807 | 0.0746 | 0.7002 | 0.7454 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0082 | 0.0068 | 0.0211 | 0.0271 | 0.0637 | 0.0780 | 0.1129 | 0.1248 | 0.0825 | 0.0753 | 0.0953 | 0.1031 | 0.6152 | 0.5848 | 0.0000 | 0.0010 | 0.0035 | 0.0129 | 0.0662 | 0.1005 | 0.0672 | 0.0985 | 0.6502 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 457 | 212 | 6322 | 18147 | 382.8 | 44.78 | 238.77 | 294.82 | 326 | 348 | 362 | 373 | 384 | 395 | 406 | 419 | 439 | 0.0600 | 1088 | 1.215 | 99.36 | 36.50 | 1 | 0.0386 | 244 | 0.0018 | 29.68 | 6.658 | 0.2214 | 148564.0 | 58400000 | 23200000000 | 9350000000000 | 0.4200 | 0.2268 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0005 | 0.0000 | 0.0033 | 0.0005 | 0.0198 | 0.0108 | 0.0385 | 0.0209 | 0.0480 | 0.0104 | 0.0811 | 0.0223 | 0.8084 | 0.9351 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0015 | 0.0005 | 0.0136 | 0.0108 | 0.0260 | 0.0209 | 0.0246 | 0.0104 | 0.0395 | 0.0223 | 0.8947 | 0.9351 | 0.0536 | 0.0000 | 0.0421 | 0.0000 | 0.0651 | 0.0000 | 0.1303 | 0.0000 | 0.1418 | 0.0000 | 0.2222 | 0.0000 | 0.1188 | 0.0000 | 0.1341 | 0.0000 | 0.0920 | 0.0000 | 0.0012 | 0.0049 | 0.0132 | 0.0292 | 0.0679 | 0.1075 | 0.1161 | 0.1588 | 0.5012 | 17 | 22 | 29 | 46 | 89 | 180 | 301 | 457 | 675 | 0.0295 | 57.83 | 5.943 | 0.4328 | 143927.0 | 117000000 | 112000000000 | 121000000000000 | 0.4463 | 0.1845 | 0.0546 | 0.0038 | 0.1914 | 0.0093 | 0.2906 | 0.1053 | 0.1701 | 0.1693 | 0.1184 | 0.2109 | 0.1042 | 0.1922 | 0.0475 | 0.1153 | 0.0156 | 0.0952 | 0.0078 | 0.0987 | 0.0001 | 0.0005 | 0.0011 | 0.0005 | 0.0034 | 0.0014 | 0.0108 | 0.0082 | 0.0532 | 0.0501 | 0.0872 | 0.0742 | 0.0606 | 0.0519 | 0.0872 | 0.0802 | 0.6963 | 0.7330 | 0.0005 | 0.0004 | 0.0021 | 0.0008 | 0.0042 | 0.0052 | 0.0150 | 0.0185 | 0.0656 | 0.0707 | 0.1028 | 0.1137 | 0.0807 | 0.0882 | 0.1081 | 0.1140 | 0.6208 | 0.5885 | 0.0002 | 0.0016 | 0.0046 | 0.0142 | 0.0602 | 0.0943 | 0.0678 | 0.0986 | 0.6586 | |
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 968 | 293 | 9056 | 13099 | 516.1 | 88.24 | 114.69 | 251.28 | 396 | 459 | 491 | 512 | 529 | 545 | 562 | 583 | 612 | 0.0837 | 1097 | 0.940 | 103.45 | 28.16 | 6 | 0.0282 | 255 | 0.0009 | 51.99 | 7.361 | 0.1986 | 274112.0 | 149000000 | 82200000000 | 46100000000000 | 0.4370 | 0.2059 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0050 | 0.0007 | 0.0278 | 0.0152 | 0.0543 | 0.0277 | 0.0482 | 0.0150 | 0.0760 | 0.0288 | 0.7879 | 0.9127 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0007 | 0.0168 | 0.0152 | 0.0317 | 0.0272 | 0.0203 | 0.0143 | 0.0351 | 0.0258 | 0.8942 | 0.9168 | 0.0106 | 0.0000 | 0.0080 | 0.0000 | 0.0359 | 0.0000 | 0.0638 | 0.0000 | 0.1237 | 0.0000 | 0.1463 | 0.0000 | 0.1077 | 0.0000 | 0.1303 | 0.0000 | 0.3737 | 0.0000 | 0.0015 | 0.0017 | 0.0063 | 0.0160 | 0.0428 | 0.0699 | 0.0713 | 0.1070 | 0.6836 | 8 | 10 | 12 | 14 | 20 | 34 | 63 | 120 | 305 | 0.0778 | 7.79 | 3.212 | 0.5546 | 76290.7 | 93700000 | 170000000000 | 429000000000000 | 0.7394 | 0.0357 | 0.0196 | 0.0006 | 0.0825 | 0.0106 | 0.1649 | 0.0417 | 0.1872 | 0.0636 | 0.1702 | 0.1514 | 0.1584 | 0.2125 | 0.1152 | 0.1383 | 0.0654 | 0.1383 | 0.0366 | 0.2430 | 0.0003 | 0.0000 | 0.0019 | 0.0013 | 0.0083 | 0.0037 | 0.0156 | 0.0088 | 0.0568 | 0.0470 | 0.0879 | 0.0948 | 0.0632 | 0.0564 | 0.0959 | 0.0866 | 0.6702 | 0.7013 | 0.0008 | 0.0005 | 0.0004 | 0.0014 | 0.0059 | 0.0028 | 0.0184 | 0.0229 | 0.0675 | 0.0744 | 0.1010 | 0.1155 | 0.0700 | 0.0734 | 0.1014 | 0.1001 | 0.6345 | 0.6090 | 0.0015 | 0.0018 | 0.0041 | 0.0170 | 0.0595 | 0.0983 | 0.0698 | 0.0953 | 0.6526 | |
MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 154 | 245 | 7441 | 18098 | 595.1 | 99.87 | 158.05 | 276.24 | 459 | 515 | 549 | 576 | 598 | 618 | 640 | 669 | 725 | 0.0530 | 960 | 0.791 | 112.90 | 27.89 | 2 | 0.0372 | 277 | 0.0011 | 26.39 | 7.165 | 0.2288 | 364116.0 | 229000000 | 147000000000 | 96900000000000 | 0.4475 | 0.1984 | 0.0002 | 0.0000 | 0.0007 | 0.0001 | 0.0016 | 0.0000 | 0.0053 | 0.0005 | 0.0258 | 0.0124 | 0.0455 | 0.0206 | 0.0458 | 0.0151 | 0.0692 | 0.0230 | 0.8059 | 0.9282 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0003 | 0.0163 | 0.0116 | 0.0267 | 0.0174 | 0.0252 | 0.0115 | 0.0358 | 0.0181 | 0.8938 | 0.9412 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0292 | 0.0000 | 0.0560 | 0.0000 | 0.0840 | 0.0000 | 0.0793 | 0.0000 | 0.1039 | 0.0000 | 0.6196 | 0.0000 | 0.0018 | 0.0036 | 0.0094 | 0.0214 | 0.0420 | 0.0641 | 0.0646 | 0.0876 | 0.7055 | 11 | 14 | 17 | 20 | 25 | 35 | 85 | 239 | 575 | 0.1535 | 16.74 | 4.037 | 0.6476 | 101285.0 | 90600000 | 95000000000 | 112000000000000 | 0.3437 | 0.2785 | 0.0470 | 0.0020 | 0.1678 | 0.0214 | 0.1893 | 0.0935 | 0.1530 | 0.1136 | 0.1732 | 0.1877 | 0.0980 | 0.1717 | 0.0779 | 0.1236 | 0.0671 | 0.1142 | 0.0268 | 0.1723 | 0.0002 | 0.0000 | 0.0008 | 0.0002 | 0.0008 | 0.0013 | 0.0102 | 0.0086 | 0.0376 | 0.0335 | 0.0599 | 0.0539 | 0.0436 | 0.0392 | 0.0626 | 0.0588 | 0.7843 | 0.8046 | 0.0000 | 0.0003 | 0.0012 | 0.0000 | 0.0042 | 0.0040 | 0.0138 | 0.0138 | 0.0413 | 0.0458 | 0.0655 | 0.0684 | 0.0487 | 0.0468 | 0.0667 | 0.0620 | 0.7586 | 0.7589 | 0.0002 | 0.0007 | 0.0023 | 0.0114 | 0.0416 | 0.0654 | 0.0444 | 0.0633 | 0.7707 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1249 | 769 | 4803 | 11247 | 502.2 | 83.00 | 67.05 | 122.38 | 382 | 431 | 463 | 488 | 508 | 528 | 552 | 579 | 608 | 0.0648 | 729 | 1.156 | 88.46 | 33.06 | 1 | 0.0477 | 229 | 0.0014 | 23.98 | 6.830 | 0.2358 | 259094.0 | 137000000 | 73800000000 | 40500000000000 | 0.4284 | 0.2133 | 0.0011 | 0.0000 | 0.0019 | 0.0000 | 0.0044 | 0.0000 | 0.0091 | 0.0002 | 0.0299 | 0.0136 | 0.0517 | 0.0206 | 0.0575 | 0.0124 | 0.0811 | 0.0183 | 0.7632 | 0.9350 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0002 | 0.0170 | 0.0136 | 0.0276 | 0.0206 | 0.0218 | 0.0124 | 0.0377 | 0.0183 | 0.8937 | 0.9350 | 0.0072 | 0.0000 | 0.0181 | 0.0000 | 0.0325 | 0.0000 | 0.0597 | 0.0000 | 0.0868 | 0.0000 | 0.1374 | 0.0000 | 0.1230 | 0.0000 | 0.1754 | 0.0000 | 0.3599 | 0.0000 | 0.0019 | 0.0016 | 0.0054 | 0.0140 | 0.0384 | 0.0594 | 0.0602 | 0.0889 | 0.7301 | 6 | 8 | 10 | 12 | 15 | 20 | 38 | 86 | 207 | 0.1665 | 6.51 | 3.350 | 0.6502 | 19470.7 | 8860000 | 4860000000 | 2970000000000 | 0.5816 | 0.0962 | 0.0324 | 0.0043 | 0.1477 | 0.0208 | 0.2216 | 0.0720 | 0.2090 | 0.1276 | 0.1658 | 0.1753 | 0.1189 | 0.1840 | 0.0613 | 0.1372 | 0.0216 | 0.1345 | 0.0216 | 0.1441 | 0.0007 | 0.0003 | 0.0010 | 0.0009 | 0.0034 | 0.0039 | 0.0172 | 0.0128 | 0.0540 | 0.0538 | 0.0890 | 0.0805 | 0.0639 | 0.0589 | 0.0907 | 0.0838 | 0.6801 | 0.7050 | 0.0000 | 0.0005 | 0.0013 | 0.0019 | 0.0030 | 0.0033 | 0.0166 | 0.0196 | 0.0675 | 0.0650 | 0.0968 | 0.1182 | 0.0739 | 0.0715 | 0.0994 | 0.1005 | 0.6416 | 0.6196 | 0.0004 | 0.0015 | 0.0034 | 0.0145 | 0.0574 | 0.1015 | 0.0624 | 0.0915 | 0.6673 | |||
SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1161 | 623 | 4896 | 12890 | 292.1 | 122.93 | 77.58 | 156.83 | 140 | 170 | 195 | 234 | 275 | 322 | 378 | 426 | 471 | 0.0714 | 920 | 0.771 | 63.56 | 16.03 | 4 | 0.0327 | 160 | 0.0010 | 16.01 | 7.132 | 0.2695 | 100453.0 | 38700000 | 16000000000 | 6940000000000 | 0.3486 | 0.2680 | 0.0008 | 0.0004 | 0.0008 | 0.0015 | 0.0008 | 0.0030 | 0.0194 | 0.0109 | 0.0891 | 0.0449 | 0.1336 | 0.0612 | 0.1263 | 0.0581 | 0.1571 | 0.0849 | 0.4721 | 0.7350 | 0.0003 | 0.0000 | 0.0003 | 0.0003 | 0.0003 | 0.0018 | 0.0061 | 0.0047 | 0.0187 | 0.0171 | 0.0224 | 0.0237 | 0.0252 | 0.0179 | 0.0330 | 0.0339 | 0.8936 | 0.9006 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0035 | 0.0053 | 0.0087 | 0.0381 | 0.0582 | 0.0545 | 0.0582 | 0.0393 | 0.0616 | 0.0527 | 0.0851 | 0.8102 | 0.7240 | 0.0000 | 0.0004 | 0.0009 | 0.0035 | 0.0274 | 0.0363 | 0.0314 | 0.0456 | 0.8544 | 7 | 9 | 11 | 13 | 17 | 25 | 42 | 84 | 223 | 0.1061 | 17.09 | 3.929 | 0.6640 | 30613.2 | 21000000 | 18400000000 | 18500000000000 | 0.3956 | 0.2278 | 0.0335 | 0.0066 | 0.0911 | 0.0183 | 0.1580 | 0.0374 | 0.2026 | 0.0682 | 0.2286 | 0.1364 | 0.1283 | 0.1540 | 0.1022 | 0.1393 | 0.0353 | 0.1598 | 0.0204 | 0.2801 | 0.0027 | 0.0025 | 0.0047 | 0.0030 | 0.0047 | 0.0050 | 0.0097 | 0.0116 | 0.0484 | 0.0449 | 0.0684 | 0.0581 | 0.0494 | 0.0512 | 0.0735 | 0.0722 | 0.7386 | 0.7516 | 0.0004 | 0.0009 | 0.0004 | 0.0004 | 0.0033 | 0.0035 | 0.0114 | 0.0097 | 0.0521 | 0.0578 | 0.0720 | 0.0843 | 0.0606 | 0.0618 | 0.0781 | 0.0856 | 0.7216 | 0.6961 | 0.0004 | 0.0011 | 0.0026 | 0.0086 | 0.0474 | 0.0784 | 0.0523 | 0.0732 | 0.7359 | |
MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 986 | 375 | 3412 | 6862 | 481.9 | 117.20 | 93.02 | 146.48 | 305 | 387 | 443 | 490 | 520 | 538 | 554 | 572 | 596 | 0.0851 | 584 | 0.932 | 72.01 | 24.21 | 1 | 0.0592 | 202 | 0.0011 | 37.12 | 7.131 | 0.2177 | 245995.0 | 130000000 | 70600000000 | 39000000000000 | 0.3975 | 0.2313 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0023 | 0.0000 | 0.0153 | 0.0006 | 0.0384 | 0.0161 | 0.0685 | 0.0274 | 0.0782 | 0.0187 | 0.1319 | 0.0332 | 0.6645 | 0.9040 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0003 | 0.0179 | 0.0160 | 0.0285 | 0.0249 | 0.0223 | 0.0150 | 0.0347 | 0.0278 | 0.8936 | 0.9159 | 0.0209 | 0.0435 | 0.0104 | 0.0000 | 0.0330 | 0.0000 | 0.0557 | 0.0435 | 0.0783 | 0.3478 | 0.0870 | 0.1739 | 0.0991 | 0.0000 | 0.1113 | 0.3043 | 0.5043 | 0.0870 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0247 | 0.0451 | 0.0400 | 0.0679 | 0.8162 | 10 | 13 | 16 | 21 | 27 | 40 | 68 | 138 | 287 | 0.0426 | 28.93 | 4.699 | 0.5709 | 30108.0 | 15300000 | 9600000000 | 6980000000000 | 0.4972 | 0.1660 | 0.0636 | 0.0056 | 0.1051 | 0.0237 | 0.0954 | 0.0847 | 0.1345 | 0.0790 | 0.1614 | 0.0926 | 0.1809 | 0.1400 | 0.1394 | 0.1264 | 0.0831 | 0.1072 | 0.0367 | 0.3409 | 0.0005 | 0.0013 | 0.0005 | 0.0017 | 0.0036 | 0.0031 | 0.0180 | 0.0144 | 0.0598 | 0.0423 | 0.0721 | 0.0737 | 0.0562 | 0.0471 | 0.0814 | 0.0702 | 0.7079 | 0.7462 | 0.0013 | 0.0000 | 0.0020 | 0.0007 | 0.0007 | 0.0000 | 0.0196 | 0.0156 | 0.0607 | 0.0675 | 0.0881 | 0.0896 | 0.0529 | 0.0490 | 0.0783 | 0.0888 | 0.6965 | 0.6887 | 0.0012 | 0.0012 | 0.0029 | 0.0175 | 0.0544 | 0.0807 | 0.0526 | 0.0807 | 0.7089 |