High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 171 | 227 | | 13156 | 26560 | 216.3 | 55.08 | 143.33 | 196.83 | 147 | 172 | 189 | 203 | 217 | 231 | 246 | 263 | 286 | 0.0570 | 1514 | 0.695 | 170.21 | 47.54 | 3 | 0.0364 | 479 | 0.0008 | 42.66 | 7.414 | 0.1765 | 49810.3 | 12100000 | 3040000000 | 797000000000 | 0.4175 | 0.2260 | 0.0007 | 0.0001 | 0.0014 | 0.0001 | 0.0076 | 0.0009 | 0.0228 | 0.0052 | 0.0655 | 0.0153 | 0.1188 | 0.0349 | 0.1344 | 0.0418 | 0.1753 | 0.0659 | 0.4735 | 0.8359 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0004 | 0.0075 | 0.0020 | 0.0220 | 0.0098 | 0.0398 | 0.0182 | 0.0480 | 0.0148 | 0.0644 | 0.0241 | 0.8168 | 0.9308 | 0.0028 | 0.0282 | 0.0118 | 0.0267 | 0.0277 | 0.0847 | 0.0602 | 0.1278 | 0.0906 | 0.1798 | 0.1387 | 0.1575 | 0.1280 | 0.1189 | 0.1505 | 0.1218 | 0.3898 | 0.1545 | 0.0012 | 0.0034 | 0.0079 | 0.0230 | 0.0477 | 0.0880 | 0.0938 | 0.1052 | 0.6296 | 16 | 19 | 22 | 26 | 40 | 80 | 154 | 256 | 424 | 0.0499 | 24.57 | 5.020 | 0.5076 | 59283.3 | 35800000 | 26400000000 | 22500000000000 | 0.6077 | 0.0916 | 0.0465 | 0.0024 | 0.1573 | 0.0221 | 0.2370 | 0.0945 | 0.1899 | 0.1299 | 0.1567 | 0.1853 | 0.1107 | 0.1877 | 0.0559 | 0.1296 | 0.0288 | 0.1216 | 0.0172 | 0.1270 | 0.0004 | 0.0003 | 0.0007 | 0.0014 | 0.0025 | 0.0019 | 0.0149 | 0.0139 | 0.0556 | 0.0499 | 0.0753 | 0.0693 | 0.0592 | 0.0511 | 0.0899 | 0.0801 | 0.7015 | 0.7321 | 0.0005 | 0.0015 | 0.0016 | 0.0014 | 0.0046 | 0.0059 | 0.0219 | 0.0234 | 0.0658 | 0.0751 | 0.1028 | 0.1190 | 0.0811 | 0.0870 | 0.1118 | 0.1202 | 0.6099 | 0.5665 | 0.0007 | 0.0013 | 0.0027 | 0.0190 | 0.0556 | 0.0905 | 0.0669 | 0.0992 | 0.6642 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 765 | 448 | | 1036 | 4704 | 600.2 | 210.48 | 6.20 | 1.84 | 332 | 391 | 444 | 509 | 577 | 659 | 743 | 818 | 904 | 0.0897 | 422 | 1.225 | 53.31 | 21.95 | 1 | 0.1332 | 138 | 0.0016 | 24.08 | 6.554 | 0.2404 | 404516.0 | 298000000 | 234000000000 | 192000000000000 | 0.3419 | 0.2894 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0031 | 0.0043 | 0.1242 | 0.0558 | 0.2329 | 0.1016 | 0.1304 | 0.0629 | 0.1739 | 0.0801 | 0.3354 | 0.6938 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0392 | 0.0339 | 0.0633 | 0.0532 | 0.0271 | 0.0271 | 0.0542 | 0.0407 | 0.8163 | 0.8439 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0324 | 0.0585 | 0.0649 | 0.0848 | 0.1135 | 0.0409 | 0.0757 | 0.0673 | 0.0811 | 0.7427 | 0.6324 | 0.0000 | 0.0000 | 0.0021 | 0.0062 | 0.0374 | 0.0811 | 0.0395 | 0.0457 | 0.7879 | 4 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 8 | 0.0274 | 6.20 | 3.980 | 0.3875 | 41.8 | 302.145 | 2320.55 | 18932.6 | 0.4537 | 0.1856 | 0.0023 | 0.0005 | 0.0113 | 0.0013 | 0.0441 | 0.0090 | 0.1027 | 0.0249 | 0.1782 | 0.0542 | 0.2398 | 0.1111 | 0.2262 | 0.2325 | 0.1613 | 0.3262 | 0.0341 | 0.2402 | 0.0000 | 0.0000 | 0.0017 | 0.0005 | 0.0047 | 0.0016 | 0.0231 | 0.0099 | 0.0540 | 0.0309 | 0.1005 | 0.0574 | 0.1816 | 0.1030 | 0.3028 | 0.2870 | 0.3314 | 0.5097 | 0.1740 | 0.3416 | 0.2290 | 0.2805 | 0.1980 | 0.1584 | 0.1530 | 0.1041 | 0.1140 | 0.0679 | 0.0770 | 0.0181 | 0.0260 | 0.0158 | 0.0230 | 0.0090 | 0.0060 | 0.0045 | 0.0029 | 0.0141 | 0.0417 | 0.0959 | 0.1617 | 0.2172 | 0.2159 | 0.1543 | 0.0962 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 949 | 842 | | 9889 | 31538 | 604.3 | 116.89 | 203.51 | 321.81 | 475 | 511 | 538 | 562 | 585 | 611 | 645 | 691 | 761 | 0.0383 | 1208 | 0.571 | 106.00 | 25.06 | 1 | 0.0342 | 338 | 0.0006 | 73.38 | 7.682 | 0.1588 | 378894.0 | 247000000 | 168000000000 | 119000000000000 | 0.4171 | 0.2369 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0004 | 0.0074 | 0.0013 | 0.0446 | 0.0124 | 0.0828 | 0.0265 | 0.0975 | 0.0233 | 0.1253 | 0.0331 | 0.6398 | 0.9031 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0005 | 0.0001 | 0.0032 | 0.0003 | 0.0237 | 0.0085 | 0.0410 | 0.0170 | 0.0490 | 0.0098 | 0.0664 | 0.0157 | 0.8162 | 0.9485 | 0.0014 | 0.0049 | 0.0084 | 0.0172 | 0.0274 | 0.0197 | 0.0556 | 0.1032 | 0.0985 | 0.1106 | 0.1343 | 0.1548 | 0.1069 | 0.1253 | 0.1153 | 0.1327 | 0.4522 | 0.3317 | 0.0012 | 0.0036 | 0.0092 | 0.0412 | 0.0736 | 0.1091 | 0.0992 | 0.1165 | 0.5465 | 8 | 9 | 12 | 17 | 48 | 103 | 192 | 355 | 647 | 0.1118 | 47.39 | 5.112 | 0.5378 | 144975.0 | 152000000 | 200000000000 | 309000000000000 | 0.3985 | 0.2132 | 0.0695 | 0.0027 | 0.2144 | 0.0263 | 0.2470 | 0.1596 | 0.1348 | 0.1210 | 0.1242 | 0.1636 | 0.0801 | 0.1770 | 0.0595 | 0.1103 | 0.0374 | 0.0928 | 0.0331 | 0.1466 | 0.0000 | 0.0001 | 0.0006 | 0.0005 | 0.0010 | 0.0014 | 0.0081 | 0.0074 | 0.0606 | 0.0447 | 0.0939 | 0.0785 | 0.0610 | 0.0514 | 0.0947 | 0.0842 | 0.6801 | 0.7319 | 0.0001 | 0.0003 | 0.0006 | 0.0005 | 0.0012 | 0.0012 | 0.0163 | 0.0192 | 0.0766 | 0.0837 | 0.1158 | 0.1356 | 0.0765 | 0.0760 | 0.1122 | 0.1199 | 0.6007 | 0.5636 | 0.0002 | 0.0005 | 0.0013 | 0.0122 | 0.0687 | 0.1051 | 0.0681 | 0.1068 | 0.6370 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 640 | 505 | | 7321 | 15664 | 132.9 | 24.36 | 203.28 | 114.00 | 103 | 113 | 120 | 126 | 131 | 137 | 144 | 152 | 164 | 0.0602 | 943 | 0.886 | 94.20 | 24.52 | 1 | 0.0328 | 240 | 0.0034 | 11.56 | 6.014 | 0.3124 | 18256.5 | 2590000 | 379000000 | 57200000000 | 0.4249 | 0.2269 | 0.0000 | 0.0001 | 0.0000 | 0.0000 | 0.0031 | 0.0001 | 0.0107 | 0.0008 | 0.0451 | 0.0126 | 0.0959 | 0.0291 | 0.1106 | 0.0302 | 0.1519 | 0.0455 | 0.5827 | 0.8815 | 0.0000 | 0.0001 | 0.0000 | 0.0000 | 0.0013 | 0.0001 | 0.0041 | 0.0006 | 0.0213 | 0.0113 | 0.0421 | 0.0206 | 0.0458 | 0.0151 | 0.0696 | 0.0214 | 0.8160 | 0.9308 | 0.0083 | 0.0311 | 0.0156 | 0.0497 | 0.0353 | 0.0807 | 0.1048 | 0.1491 | 0.1566 | 0.2609 | 0.1940 | 0.1677 | 0.1193 | 0.0621 | 0.1421 | 0.1429 | 0.2241 | 0.0559 | 0.0026 | 0.0048 | 0.0145 | 0.0318 | 0.0705 | 0.1166 | 0.1066 | 0.1362 | 0.5163 | 66 | 100 | 130 | 159 | 188 | 221 | 256 | 298 | 361 | 0.0013 | 36.57 | 7.039 | 0.2500 | 54319.8 | 17300000 | 6280000000 | 2520000000000 | 0.5417 | 0.1374 | 0.0116 | 0.0006 | 0.0610 | 0.0034 | 0.1692 | 0.0206 | 0.1815 | 0.0547 | 0.2027 | 0.1259 | 0.1727 | 0.1917 | 0.1056 | 0.1593 | 0.0625 | 0.1770 | 0.0330 | 0.2666 | 0.0005 | 0.0002 | 0.0016 | 0.0004 | 0.0064 | 0.0030 | 0.0191 | 0.0101 | 0.0584 | 0.0425 | 0.1194 | 0.0871 | 0.0931 | 0.0697 | 0.1203 | 0.1000 | 0.5810 | 0.6870 | 0.0025 | 0.0036 | 0.0078 | 0.0101 | 0.0228 | 0.0258 | 0.0457 | 0.0697 | 0.1071 | 0.1403 | 0.1660 | 0.1930 | 0.1333 | 0.1409 | 0.1465 | 0.1479 | 0.3682 | 0.2686 | 0.0013 | 0.0039 | 0.0104 | 0.0303 | 0.0787 | 0.1477 | 0.1131 | 0.1412 | 0.4735 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 350 | 768 | | 2148 | 7377 | 649.8 | 190.42 | 59.61 | 108.11 | 361 | 467 | 544 | 624 | 689 | 729 | 767 | 811 | 863 | 0.0729 | 538 | 0.439 | 61.06 | 9.22 | 3 | 0.0791 | 170 | 0.0009 | 72.75 | 7.161 | 0.1651 | 458473.0 | 344000000 | 270000000000 | 221000000000000 | 0.4160 | 0.2058 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0006 | 0.0291 | 0.0023 | 0.0824 | 0.0283 | 0.1568 | 0.0702 | 0.1075 | 0.0385 | 0.1397 | 0.0645 | 0.4794 | 0.7957 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0045 | 0.0016 | 0.0293 | 0.0240 | 0.0560 | 0.0464 | 0.0350 | 0.0235 | 0.0592 | 0.0427 | 0.8160 | 0.8617 | 0.0000 | 0.0094 | 0.0000 | 0.0283 | 0.0035 | 0.0189 | 0.0260 | 0.0566 | 0.0781 | 0.1415 | 0.1163 | 0.2264 | 0.0885 | 0.0472 | 0.1250 | 0.1038 | 0.5625 | 0.3679 | 0.0000 | 0.0000 | 0.0000 | 0.0091 | 0.0432 | 0.0639 | 0.0490 | 0.0763 | 0.7585 | 7 | 9 | 11 | 13 | 16 | 21 | 32 | 64 | 203 | 0.0746 | 10.49 | 3.983 | 0.6307 | 15239.4 | 6560000 | 3660000000 | 2420000000000 | 0.2920 | 0.3302 | 0.0000 | 0.0050 | 0.0655 | 0.0113 | 0.2143 | 0.0239 | 0.2292 | 0.0642 | 0.2054 | 0.1597 | 0.1429 | 0.2013 | 0.0774 | 0.1660 | 0.0506 | 0.1698 | 0.0149 | 0.1987 | 0.0000 | 0.0019 | 0.0017 | 0.0043 | 0.0040 | 0.0038 | 0.0115 | 0.0125 | 0.0340 | 0.0355 | 0.0530 | 0.0485 | 0.0363 | 0.0384 | 0.0594 | 0.0677 | 0.8000 | 0.7872 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0043 | 0.0031 | 0.0129 | 0.0109 | 0.0372 | 0.0427 | 0.0558 | 0.0637 | 0.0393 | 0.0365 | 0.0629 | 0.0637 | 0.7877 | 0.7793 | 0.0000 | 0.0000 | 0.0007 | 0.0170 | 0.0352 | 0.0483 | 0.0463 | 0.0614 | 0.7911 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 998 | 485 | | 4473 | 15868 | 223.3 | 42.57 | 170.54 | 190.66 | 167 | 185 | 199 | 211 | 221 | 232 | 244 | 259 | 279 | 0.0531 | 843 | 0.739 | 107.82 | 35.01 | 1 | 0.0722 | 323 | 0.0012 | 31.42 | 6.899 | 0.2014 | 51676.7 | 12400000 | 3060000000 | 781000000000 | 0.4192 | 0.2236 | 0.0016 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0000 | 0.0147 | 0.0009 | 0.0482 | 0.0156 | 0.1042 | 0.0328 | 0.1130 | 0.0248 | 0.1586 | 0.0425 | 0.5557 | 0.8834 | 0.0013 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0048 | 0.0002 | 0.0213 | 0.0134 | 0.0435 | 0.0239 | 0.0437 | 0.0125 | 0.0680 | 0.0215 | 0.8155 | 0.9284 | 0.0073 | 0.0174 | 0.0132 | 0.0174 | 0.0323 | 0.0348 | 0.0852 | 0.1826 | 0.1160 | 0.1739 | 0.1880 | 0.2000 | 0.1483 | 0.1217 | 0.1219 | 0.1043 | 0.2878 | 0.1478 | 0.0018 | 0.0050 | 0.0055 | 0.0315 | 0.0721 | 0.1132 | 0.1178 | 0.1251 | 0.5279 | 12 | 17 | 28 | 49 | 86 | 143 | 221 | 333 | 461 | 0.0266 | 31.54 | 5.838 | 0.4485 | 65434.3 | 33400000 | 20100000000 | 13900000000000 | 0.5142 | 0.1765 | 0.0522 | 0.0024 | 0.1949 | 0.0152 | 0.2023 | 0.0988 | 0.1266 | 0.1475 | 0.1199 | 0.1915 | 0.1098 | 0.1664 | 0.0831 | 0.1072 | 0.0522 | 0.0954 | 0.0589 | 0.1756 | 0.0003 | 0.0004 | 0.0003 | 0.0008 | 0.0018 | 0.0008 | 0.0091 | 0.0077 | 0.0519 | 0.0426 | 0.0874 | 0.0779 | 0.0733 | 0.0632 | 0.1020 | 0.0877 | 0.6738 | 0.7190 | 0.0004 | 0.0004 | 0.0014 | 0.0034 | 0.0038 | 0.0054 | 0.0148 | 0.0199 | 0.0648 | 0.0719 | 0.1143 | 0.1171 | 0.0843 | 0.0862 | 0.1204 | 0.1209 | 0.5958 | 0.5749 | 0.0003 | 0.0012 | 0.0037 | 0.0126 | 0.0592 | 0.0980 | 0.0826 | 0.1114 | 0.6309 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 283 | 97 | | 3964 | 10522 | 352.2 | 81.30 | 461.34 | 382.37 | 252 | 288 | 313 | 334 | 354 | 372 | 392 | 416 | 452 | 0.0657 | 691 | 0.753 | 95.27 | 24.08 | 1 | 0.0658 | 261 | 0.0006 | 102.74 | 7.612 | 0.1258 | 130633.0 | 50600000 | 20400000000 | 8530000000000 | 0.4023 | 0.2386 | 0.0008 | 0.0000 | 0.0008 | 0.0000 | 0.0043 | 0.0000 | 0.0179 | 0.0014 | 0.0550 | 0.0209 | 0.1072 | 0.0390 | 0.1228 | 0.0329 | 0.1454 | 0.0549 | 0.5458 | 0.8510 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0061 | 0.0013 | 0.0223 | 0.0154 | 0.0444 | 0.0260 | 0.0471 | 0.0172 | 0.0640 | 0.0262 | 0.8145 | 0.9139 | 0.0000 | 0.0109 | 0.0100 | 0.0109 | 0.0242 | 0.0217 | 0.0627 | 0.1033 | 0.1296 | 0.1467 | 0.1553 | 0.1413 | 0.1254 | 0.1196 | 0.1538 | 0.1033 | 0.3390 | 0.3424 | 0.0010 | 0.0035 | 0.0049 | 0.0233 | 0.0673 | 0.1054 | 0.1049 | 0.1242 | 0.5656 | 46 | 92 | 175 | 276 | 376 | 494 | 622 | 777 | 1000 | 0.0020 | 93.98 | 7.546 | 0.2428 | 359026.0 | 355000000 | 407000000000 | 521000000000000 | 0.5626 | 0.1363 | 0.0068 | 0.0015 | 0.0542 | 0.0057 | 0.1423 | 0.0121 | 0.1725 | 0.0508 | 0.1725 | 0.1309 | 0.1744 | 0.1967 | 0.1072 | 0.1517 | 0.0930 | 0.1565 | 0.0770 | 0.2940 | 0.0004 | 0.0000 | 0.0039 | 0.0011 | 0.0049 | 0.0030 | 0.0161 | 0.0105 | 0.0447 | 0.0377 | 0.0709 | 0.0692 | 0.0629 | 0.0510 | 0.0765 | 0.0729 | 0.7196 | 0.7546 | 0.0008 | 0.0007 | 0.0027 | 0.0023 | 0.0065 | 0.0073 | 0.0220 | 0.0293 | 0.0578 | 0.0676 | 0.0957 | 0.1119 | 0.0774 | 0.0916 | 0.1013 | 0.1196 | 0.6358 | 0.5696 | 0.0002 | 0.0022 | 0.0038 | 0.0146 | 0.0510 | 0.0864 | 0.0649 | 0.0858 | 0.6910 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 726 | 600 | | 3242 | 14311 | 499.5 | 83.43 | 217.74 | 192.04 | 394 | 426 | 450 | 470 | 493 | 518 | 547 | 576 | 612 | 0.0641 | 917 | 0.675 | 101.83 | 25.18 | 1 | 0.0999 | 324 | 0.0014 | 30.06 | 6.786 | 0.2232 | 256441.0 | 135000000 | 73000000000 | 40400000000000 | 0.4615 | 0.1909 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0029 | 0.0003 | 0.0094 | 0.0019 | 0.0476 | 0.0128 | 0.1034 | 0.0350 | 0.0932 | 0.0172 | 0.1211 | 0.0428 | 0.6215 | 0.8900 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0031 | 0.0015 | 0.0241 | 0.0115 | 0.0544 | 0.0319 | 0.0457 | 0.0124 | 0.0582 | 0.0254 | 0.8139 | 0.9170 | 0.0069 | 0.2000 | 0.0185 | 0.2000 | 0.0254 | 0.1333 | 0.0762 | 0.2667 | 0.1224 | 0.0667 | 0.2517 | 0.1333 | 0.1201 | 0.0000 | 0.1386 | 0.0000 | 0.2402 | 0.0000 | 0.0026 | 0.0013 | 0.0110 | 0.0272 | 0.0725 | 0.1146 | 0.0881 | 0.1075 | 0.5751 | 27 | 59 | 91 | 117 | 149 | 197 | 277 | 373 | 502 | 0.0056 | 39.72 | 6.385 | 0.3525 | 84287.2 | 43400000 | 26300000000 | 17700000000000 | 0.5008 | 0.1648 | 0.0367 | 0.0032 | 0.1371 | 0.0092 | 0.2234 | 0.0566 | 0.1856 | 0.1095 | 0.1607 | 0.1802 | 0.1201 | 0.1909 | 0.0615 | 0.1404 | 0.0434 | 0.1268 | 0.0316 | 0.1831 | 0.0010 | 0.0008 | 0.0021 | 0.0015 | 0.0046 | 0.0040 | 0.0193 | 0.0143 | 0.0618 | 0.0534 | 0.0900 | 0.0837 | 0.0683 | 0.0638 | 0.1015 | 0.0908 | 0.6515 | 0.6878 | 0.0004 | 0.0008 | 0.0007 | 0.0042 | 0.0048 | 0.0124 | 0.0253 | 0.0287 | 0.0830 | 0.0944 | 0.1247 | 0.1404 | 0.1000 | 0.1138 | 0.1419 | 0.1548 | 0.5192 | 0.4506 | 0.0006 | 0.0023 | 0.0015 | 0.0250 | 0.0581 | 0.1139 | 0.0806 | 0.1154 | 0.6027 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 424 | 598 | | 10118 | 27401 | 44.6 | 15.32 | 9.66 | 10.14 | 26 | 30 | 34 | 39 | 43 | 46 | 51 | 58 | 68 | 0.0697 | 1910 | 0.653 | 52.00 | 10.05 | 2 | 0.0153 | 155 | 0.0320 | 0.80 | 3.734 | 0.7116 | 2220.7 | 121956 | 7260000 | 460000000 | 0.4370 | 0.1928 | 0.0033 | 0.0009 | 0.0117 | 0.0021 | 0.0212 | 0.0062 | 0.0405 | 0.0162 | 0.0660 | 0.0337 | 0.0944 | 0.0462 | 0.1215 | 0.0617 | 0.1775 | 0.0854 | 0.4639 | 0.7475 | 0.0012 | 0.0004 | 0.0041 | 0.0011 | 0.0082 | 0.0029 | 0.0150 | 0.0080 | 0.0223 | 0.0197 | 0.0297 | 0.0256 | 0.0429 | 0.0335 | 0.0634 | 0.0478 | 0.8132 | 0.8611 | 0.0054 | 0.0041 | 0.0122 | 0.0117 | 0.0168 | 0.0233 | 0.0337 | 0.0425 | 0.0471 | 0.0487 | 0.0631 | 0.0720 | 0.0608 | 0.0822 | 0.0838 | 0.0864 | 0.6771 | 0.6292 | 0.0039 | 0.0100 | 0.0142 | 0.0234 | 0.0345 | 0.0395 | 0.0542 | 0.0860 | 0.7342 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 11 | 16 | 0.0607 | 0.27 | 1.084 | 0.3393 | 196.2 | 10715.8 | 1130000 | 163000000 | 0.5653 | 0.1216 | 0.0777 | 0.0043 | 0.1202 | 0.0147 | 0.1403 | 0.0416 | 0.1602 | 0.0819 | 0.1662 | 0.1200 | 0.1599 | 0.1529 | 0.1160 | 0.1781 | 0.0486 | 0.2087 | 0.0109 | 0.1979 | 0.0433 | 0.0019 | 0.0675 | 0.0095 | 0.0728 | 0.0304 | 0.0744 | 0.0626 | 0.0830 | 0.0967 | 0.0877 | 0.1232 | 0.0996 | 0.1307 | 0.1151 | 0.1503 | 0.3566 | 0.3946 | 0.0629 | 0.0327 | 0.0480 | 0.0262 | 0.0487 | 0.0276 | 0.0411 | 0.0316 | 0.0533 | 0.0584 | 0.0696 | 0.0784 | 0.0791 | 0.0835 | 0.1064 | 0.1232 | 0.4909 | 0.5384 | 0.0684 | 0.0635 | 0.0650 | 0.0662 | 0.0726 | 0.0769 | 0.0668 | 0.0896 | 0.4311 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 946 | 255 | | 1237 | 5097 | 597.6 | 154.71 | 26.89 | 29.04 | 397 | 436 | 482 | 531 | 589 | 647 | 701 | 753 | 822 | 0.1214 | 619 | 1.247 | 102.24 | 42.95 | 1 | 0.2183 | 270 | 0.0018 | 17.17 | 6.438 | 0.2538 | 381056.0 | 257000000 | 181000000000 | 133000000000000 | 0.3962 | 0.2297 | 0.0000 | 0.0000 | 0.0037 | 0.0009 | 0.0093 | 0.0018 | 0.0223 | 0.0080 | 0.0801 | 0.0312 | 0.1657 | 0.0714 | 0.1192 | 0.0562 | 0.1546 | 0.0714 | 0.4451 | 0.7591 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0092 | 0.0016 | 0.0264 | 0.0246 | 0.0608 | 0.0493 | 0.0321 | 0.0271 | 0.0585 | 0.0427 | 0.8131 | 0.8539 | 0.0000 | 0.0103 | 0.0000 | 0.0206 | 0.0060 | 0.0412 | 0.0269 | 0.0619 | 0.0716 | 0.1443 | 0.1134 | 0.1753 | 0.0866 | 0.0825 | 0.0925 | 0.1753 | 0.6030 | 0.2887 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0434 | 0.0634 | 0.0467 | 0.0768 | 0.7596 | 6 | 7 | 8 | 10 | 13 | 19 | 28 | 45 | 74 | 0.1481 | 0.93 | 2.851 | 0.7106 | 1566.2 | 129062 | 12400000 | 1310000000 | 0.4006 | 0.2163 | 0.0291 | 0.0139 | 0.1414 | 0.0268 | 0.2557 | 0.0606 | 0.2370 | 0.1480 | 0.1705 | 0.2205 | 0.1019 | 0.1768 | 0.0437 | 0.1609 | 0.0146 | 0.1231 | 0.0062 | 0.0695 | 0.0016 | 0.0054 | 0.0022 | 0.0054 | 0.0141 | 0.0117 | 0.0255 | 0.0252 | 0.0662 | 0.0667 | 0.0950 | 0.0812 | 0.0787 | 0.0744 | 0.0944 | 0.1019 | 0.6224 | 0.6280 | 0.0029 | 0.0025 | 0.0059 | 0.0033 | 0.0095 | 0.0190 | 0.0352 | 0.0355 | 0.0808 | 0.0809 | 0.0932 | 0.0884 | 0.0712 | 0.0710 | 0.0991 | 0.1057 | 0.6021 | 0.5937 | 0.0025 | 0.0056 | 0.0124 | 0.0324 | 0.0678 | 0.1008 | 0.0716 | 0.0965 | 0.6105 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 227 | 700 | | 2457 | 15737 | 289.2 | 101.50 | 9.59 | 3.09 | 185 | 205 | 224 | 243 | 262 | 282 | 308 | 358 | 452 | 0.0555 | 874 | 1.038 | 40.80 | 14.42 | 1 | 0.0456 | 112 | 0.0046 | 7.54 | 5.814 | 0.3959 | 93934.6 | 34400000 | 14000000000 | 6220000000000 | 0.3996 | 0.2284 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0010 | 0.0200 | 0.0095 | 0.0763 | 0.0322 | 0.1117 | 0.0548 | 0.0981 | 0.0497 | 0.1154 | 0.0724 | 0.5722 | 0.7804 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0008 | 0.0110 | 0.0064 | 0.0318 | 0.0187 | 0.0434 | 0.0314 | 0.0446 | 0.0263 | 0.0532 | 0.0403 | 0.8128 | 0.8760 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0019 | 0.0027 | 0.0206 | 0.0247 | 0.0468 | 0.0630 | 0.0880 | 0.0904 | 0.0637 | 0.0685 | 0.0787 | 0.0986 | 0.6966 | 0.6521 | 0.0011 | 0.0022 | 0.0043 | 0.0183 | 0.0539 | 0.0766 | 0.0583 | 0.0798 | 0.7055 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 12 | 14 | 0.0103 | 12.47 | 4.932 | 0.3085 | 101.5 | 1173.91 | 14746.7 | 200713 | 0.4806 | 0.1663 | 0.0121 | 0.0008 | 0.0519 | 0.0024 | 0.1150 | 0.0081 | 0.1984 | 0.0215 | 0.2311 | 0.0482 | 0.1959 | 0.0974 | 0.1331 | 0.1901 | 0.0517 | 0.3239 | 0.0108 | 0.3077 | 0.0032 | 0.0001 | 0.0147 | 0.0004 | 0.0283 | 0.0024 | 0.0519 | 0.0078 | 0.0814 | 0.0224 | 0.1134 | 0.0398 | 0.1727 | 0.0801 | 0.2397 | 0.2135 | 0.2946 | 0.6336 | 0.0921 | 0.2202 | 0.1323 | 0.1939 | 0.1418 | 0.1653 | 0.1471 | 0.1289 | 0.1473 | 0.1008 | 0.1225 | 0.0776 | 0.0936 | 0.0519 | 0.0695 | 0.0328 | 0.0537 | 0.0286 | 0.0234 | 0.0575 | 0.0810 | 0.1141 | 0.1428 | 0.1680 | 0.1726 | 0.1435 | 0.0970 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 558 | 297 | | 5154 | 21541 | 500.5 | 100.92 | 62.27 | 98.68 | 379 | 413 | 441 | 465 | 489 | 516 | 545 | 583 | 643 | 0.0452 | 974 | 1.154 | 82.42 | 31.26 | 1 | 0.0415 | 214 | 0.0008 | 54.34 | 7.369 | 0.1710 | 260702.0 | 141000000 | 79400000000 | 46200000000000 | 0.4202 | 0.2271 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0017 | 0.0002 | 0.0098 | 0.0012 | 0.0500 | 0.0161 | 0.1015 | 0.0368 | 0.0980 | 0.0279 | 0.1322 | 0.0328 | 0.6056 | 0.8850 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0006 | 0.0245 | 0.0117 | 0.0493 | 0.0242 | 0.0433 | 0.0125 | 0.0646 | 0.0189 | 0.8118 | 0.9320 | 0.0012 | 0.0000 | 0.0048 | 0.0048 | 0.0119 | 0.0193 | 0.0523 | 0.1063 | 0.1010 | 0.1401 | 0.1354 | 0.2415 | 0.0926 | 0.0918 | 0.1330 | 0.1594 | 0.4679 | 0.2367 | 0.0004 | 0.0034 | 0.0068 | 0.0256 | 0.0631 | 0.1062 | 0.0981 | 0.1207 | 0.5755 | 7 | 8 | 9 | 11 | 13 | 22 | 54 | 107 | 186 | 0.1524 | 8.90 | 3.882 | 0.6556 | 13615.0 | 4670000 | 2040000000 | 1060000000000 | 0.5472 | 0.1233 | 0.0212 | 0.0048 | 0.0778 | 0.0100 | 0.2184 | 0.0291 | 0.2431 | 0.0917 | 0.2007 | 0.1943 | 0.1344 | 0.2273 | 0.0654 | 0.1586 | 0.0309 | 0.1369 | 0.0080 | 0.1473 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0018 | 0.0020 | 0.0078 | 0.0083 | 0.0383 | 0.0319 | 0.0619 | 0.0584 | 0.0403 | 0.0398 | 0.0605 | 0.0521 | 0.7895 | 0.8065 | 0.0000 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0038 | 0.0112 | 0.0113 | 0.0443 | 0.0457 | 0.0656 | 0.0707 | 0.0474 | 0.0532 | 0.0740 | 0.0811 | 0.7534 | 0.7324 | 0.0003 | 0.0000 | 0.0021 | 0.0080 | 0.0402 | 0.0651 | 0.0435 | 0.0623 | 0.7784 | ||
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 328 | 264 | | 5714 | 20546 | 463.9 | 85.65 | 198.91 | 273.07 | 350 | 385 | 413 | 441 | 466 | 489 | 515 | 542 | 578 | 0.0555 | 1140 | 1.175 | 43.60 | 17.69 | 1 | 0.0201 | 115 | 0.0019 | 18.72 | 6.494 | 0.2565 | 222566.0 | 110000000 | 55900000000 | 29000000000000 | 0.4221 | 0.2293 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0015 | 0.0000 | 0.0127 | 0.0002 | 0.0579 | 0.0130 | 0.1134 | 0.0244 | 0.1170 | 0.0200 | 0.1731 | 0.0342 | 0.5233 | 0.9083 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0012 | 0.0000 | 0.0052 | 0.0002 | 0.0208 | 0.0122 | 0.0470 | 0.0219 | 0.0414 | 0.0133 | 0.0718 | 0.0193 | 0.8118 | 0.9331 | 0.0079 | 0.1000 | 0.0068 | 0.2500 | 0.0294 | 0.0750 | 0.0791 | 0.2000 | 0.1672 | 0.2250 | 0.2045 | 0.1000 | 0.1593 | 0.0500 | 0.1390 | 0.0000 | 0.2068 | 0.0000 | 0.0010 | 0.0021 | 0.0058 | 0.0158 | 0.0586 | 0.1059 | 0.0991 | 0.1464 | 0.5653 | 11 | 13 | 16 | 27 | 66 | 139 | 232 | 357 | 585 | 0.0741 | 43.15 | 5.361 | 0.5048 | 114131.0 | 92700000 | 90900000000 | 100000000000000 | 0.4547 | 0.1787 | 0.0206 | 0.0015 | 0.0989 | 0.0062 | 0.1742 | 0.0387 | 0.1784 | 0.0968 | 0.1954 | 0.1780 | 0.1632 | 0.1878 | 0.0692 | 0.1270 | 0.0643 | 0.1385 | 0.0358 | 0.2256 | 0.0000 | 0.0002 | 0.0004 | 0.0001 | 0.0016 | 0.0013 | 0.0107 | 0.0056 | 0.0397 | 0.0367 | 0.0708 | 0.0642 | 0.0517 | 0.0460 | 0.0770 | 0.0672 | 0.7482 | 0.7786 | 0.0000 | 0.0006 | 0.0017 | 0.0009 | 0.0036 | 0.0038 | 0.0119 | 0.0147 | 0.0501 | 0.0553 | 0.0831 | 0.0909 | 0.0729 | 0.0815 | 0.0904 | 0.0975 | 0.6863 | 0.6548 | 0.0004 | 0.0006 | 0.0018 | 0.0106 | 0.0445 | 0.0816 | 0.0606 | 0.0805 | 0.7194 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 958 | 125 | | 2932 | 10604 | 196.6 | 65.96 | 9.01 | 4.41 | 127 | 138 | 150 | 164 | 179 | 198 | 223 | 249 | 301 | 0.0658 | 698 | 0.614 | 76.01 | 21.95 | 1 | 0.0836 | 245 | 0.0079 | 2.74 | 5.180 | 0.5006 | 42980.6 | 10400000 | 2760000000 | 788000000000 | 0.4076 | 0.2304 | 0.0043 | 0.0013 | 0.0035 | 0.0013 | 0.0112 | 0.0042 | 0.0371 | 0.0097 | 0.0569 | 0.0295 | 0.1320 | 0.0687 | 0.1217 | 0.0442 | 0.1639 | 0.0720 | 0.4694 | 0.7692 | 0.0021 | 0.0011 | 0.0021 | 0.0007 | 0.0053 | 0.0032 | 0.0137 | 0.0064 | 0.0217 | 0.0207 | 0.0455 | 0.0454 | 0.0418 | 0.0264 | 0.0561 | 0.0482 | 0.8117 | 0.8477 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0109 | 0.0047 | 0.0301 | 0.0165 | 0.0342 | 0.0425 | 0.0861 | 0.0778 | 0.0697 | 0.0472 | 0.0765 | 0.0802 | 0.6899 | 0.7311 | 0.0017 | 0.0025 | 0.0042 | 0.0151 | 0.0260 | 0.0519 | 0.0511 | 0.0611 | 0.7864 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 14 | 0.0111 | 13.72 | 5.076 | 0.3038 | 100.7 | 1416.1 | 25055.2 | 539238 | 0.4587 | 0.1802 | 0.0400 | 0.0040 | 0.1247 | 0.0070 | 0.2092 | 0.0206 | 0.2582 | 0.0465 | 0.1991 | 0.1010 | 0.1141 | 0.1792 | 0.0447 | 0.2550 | 0.0098 | 0.2595 | 0.0003 | 0.1273 | 0.0087 | 0.0002 | 0.0392 | 0.0012 | 0.0841 | 0.0078 | 0.1282 | 0.0233 | 0.1444 | 0.0654 | 0.1470 | 0.1201 | 0.1169 | 0.1781 | 0.1209 | 0.2377 | 0.2107 | 0.3662 | 0.1147 | 0.1071 | 0.0900 | 0.0750 | 0.0862 | 0.0679 | 0.0718 | 0.0968 | 0.0938 | 0.0859 | 0.1045 | 0.1000 | 0.0836 | 0.1019 | 0.0957 | 0.1167 | 0.2595 | 0.2487 | 0.0483 | 0.0956 | 0.1102 | 0.1089 | 0.1085 | 0.0986 | 0.0902 | 0.1128 | 0.2269 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1002 | 903 | | 2590 | 6854 | 671.8 | 130.82 | 57.85 | 118.91 | 504 | 556 | 597 | 632 | 666 | 700 | 730 | 773 | 852 | 0.0926 | 635 | 0.749 | 181.18 | 45.31 | 2 | 0.1853 | 480 | 0.0008 | 66.05 | 7.317 | 0.1448 | 468423.0 | 339000000 | 253000000000 | 195000000000000 | 0.4212 | 0.2260 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0004 | 0.0062 | 0.0020 | 0.0506 | 0.0208 | 0.1069 | 0.0425 | 0.0771 | 0.0261 | 0.1187 | 0.0357 | 0.6398 | 0.8725 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0032 | 0.0008 | 0.0272 | 0.0159 | 0.0614 | 0.0348 | 0.0378 | 0.0147 | 0.0591 | 0.0224 | 0.8113 | 0.9111 | 0.0051 | 0.0000 | 0.0000 | 0.0000 | 0.0103 | 0.0220 | 0.0282 | 0.0879 | 0.0872 | 0.1209 | 0.1385 | 0.1758 | 0.0923 | 0.1868 | 0.1256 | 0.1538 | 0.5128 | 0.2527 | 0.0008 | 0.0000 | 0.0040 | 0.0217 | 0.0593 | 0.1051 | 0.0842 | 0.1043 | 0.6207 | 10 | 12 | 13 | 16 | 22 | 33 | 42 | 64 | 129 | 0.1077 | 12.25 | 3.455 | 0.7303 | 17483.7 | 14800000 | 20400000000 | 35900000000000 | 0.6243 | 0.0943 | 0.0239 | 0.0079 | 0.0613 | 0.0126 | 0.0733 | 0.0238 | 0.1346 | 0.0516 | 0.1891 | 0.0827 | 0.1704 | 0.1263 | 0.1891 | 0.1468 | 0.1193 | 0.1640 | 0.0392 | 0.3843 | 0.0054 | 0.0046 | 0.0113 | 0.0057 | 0.0097 | 0.0092 | 0.0199 | 0.0218 | 0.0485 | 0.0402 | 0.0889 | 0.0766 | 0.0711 | 0.0808 | 0.0867 | 0.0938 | 0.6584 | 0.6673 | 0.0039 | 0.0018 | 0.0024 | 0.0027 | 0.0087 | 0.0064 | 0.0221 | 0.0282 | 0.0559 | 0.0645 | 0.1087 | 0.1064 | 0.0693 | 0.0709 | 0.0969 | 0.0982 | 0.6320 | 0.6209 | 0.0026 | 0.0066 | 0.0066 | 0.0178 | 0.0540 | 0.0949 | 0.0639 | 0.0988 | 0.6548 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 771 | 431 | | 4723 | 9875 | 420.9 | 161.67 | 55.15 | 99.89 | 200 | 251 | 303 | 365 | 431 | 482 | 522 | 568 | 629 | 0.0788 | 778 | 0.731 | 105.48 | 21.21 | 6 | 0.0565 | 267 | 0.0006 | 80.85 | 7.710 | 0.1749 | 203288.0 | 108000000 | 61500000000 | 36800000000000 | 0.4984 | 0.1471 | 0.0007 | 0.0003 | 0.0007 | 0.0010 | 0.0216 | 0.0033 | 0.0404 | 0.0080 | 0.1246 | 0.0501 | 0.1865 | 0.0951 | 0.1461 | 0.0607 | 0.1538 | 0.0921 | 0.3257 | 0.6894 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0046 | 0.0034 | 0.0355 | 0.0308 | 0.0624 | 0.0490 | 0.0309 | 0.0300 | 0.0558 | 0.0477 | 0.8106 | 0.8391 | 0.0012 | 0.0000 | 0.0025 | 0.0000 | 0.0037 | 0.0000 | 0.0211 | 0.0000 | 0.0460 | 0.0000 | 0.0814 | 0.0000 | 0.0534 | 0.0000 | 0.0764 | 0.0000 | 0.7141 | 1.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0061 | 0.0442 | 0.0626 | 0.0421 | 0.0646 | 0.7799 | 10 | 11 | 12 | 13 | 15 | 20 | 30 | 66 | 151 | 0.2033 | 1.45 | 2.515 | 0.7047 | 13017.7 | 5530000 | 3000000000 | 1870000000000 | 0.6272 | 0.0766 | 0.0281 | 0.0028 | 0.0884 | 0.0139 | 0.1165 | 0.0558 | 0.1908 | 0.0883 | 0.2028 | 0.1403 | 0.1767 | 0.1589 | 0.1145 | 0.1608 | 0.0643 | 0.1673 | 0.0181 | 0.2119 | 0.0004 | 0.0007 | 0.0008 | 0.0010 | 0.0012 | 0.0042 | 0.0132 | 0.0178 | 0.0474 | 0.0437 | 0.0783 | 0.0615 | 0.0602 | 0.0612 | 0.0799 | 0.0829 | 0.7186 | 0.7269 | 0.0000 | 0.0000 | 0.0010 | 0.0011 | 0.0055 | 0.0056 | 0.0146 | 0.0202 | 0.0592 | 0.0633 | 0.0933 | 0.0959 | 0.0607 | 0.0774 | 0.0933 | 0.0970 | 0.6724 | 0.6396 | 0.0005 | 0.0000 | 0.0027 | 0.0140 | 0.0564 | 0.0794 | 0.0609 | 0.0947 | 0.6916 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 430 | | 9439 | 30387 | 187.6 | 49.18 | 85.43 | 137.20 | 127 | 150 | 163 | 176 | 187 | 199 | 211 | 226 | 249 | 0.0448 | 1360 | 0.978 | 133.06 | 44.05 | 3 | 0.0366 | 345 | 0.0011 | 36.27 | 7.174 | 0.1963 | 37625.0 | 7970000 | 1770000000 | 413000000000 | 0.4260 | 0.2189 | 0.0002 | 0.0000 | 0.0009 | 0.0001 | 0.0043 | 0.0007 | 0.0199 | 0.0027 | 0.0634 | 0.0169 | 0.1233 | 0.0399 | 0.1423 | 0.0401 | 0.1734 | 0.0580 | 0.4723 | 0.8415 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0072 | 0.0010 | 0.0225 | 0.0102 | 0.0434 | 0.0235 | 0.0516 | 0.0149 | 0.0628 | 0.0250 | 0.8102 | 0.9254 | 0.0063 | 0.0066 | 0.0083 | 0.0115 | 0.0276 | 0.0508 | 0.0683 | 0.0869 | 0.1017 | 0.1328 | 0.1424 | 0.1410 | 0.1226 | 0.1016 | 0.1346 | 0.1279 | 0.3881 | 0.3410 | 0.0009 | 0.0032 | 0.0071 | 0.0234 | 0.0626 | 0.0939 | 0.0934 | 0.1316 | 0.5841 | 10 | 12 | 14 | 16 | 20 | 29 | 62 | 140 | 267 | 0.1579 | 16.30 | 3.924 | 0.6407 | 26120.0 | 12600000 | 7750000000 | 5660000000000 | 0.5727 | 0.1271 | 0.1171 | 0.0076 | 0.2705 | 0.0420 | 0.2342 | 0.2186 | 0.1164 | 0.1757 | 0.1023 | 0.1567 | 0.0686 | 0.1384 | 0.0444 | 0.0856 | 0.0316 | 0.0752 | 0.0148 | 0.1002 | 0.0003 | 0.0005 | 0.0015 | 0.0008 | 0.0032 | 0.0031 | 0.0147 | 0.0133 | 0.0655 | 0.0528 | 0.0960 | 0.0906 | 0.0648 | 0.0549 | 0.0997 | 0.0876 | 0.6543 | 0.6964 | 0.0001 | 0.0004 | 0.0007 | 0.0004 | 0.0029 | 0.0039 | 0.0241 | 0.0258 | 0.0759 | 0.0823 | 0.1193 | 0.1295 | 0.0787 | 0.0827 | 0.1092 | 0.1138 | 0.5892 | 0.5612 | 0.0004 | 0.0010 | 0.0023 | 0.0194 | 0.0694 | 0.1084 | 0.0725 | 0.1053 | 0.6214 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1104 | 606 | | 7792 | 17317 | 455.1 | 84.64 | 91.04 | 159.85 | 350 | 380 | 405 | 428 | 449 | 472 | 497 | 528 | 568 | 0.0587 | 1017 | 0.843 | 136.49 | 39.96 | 1 | 0.0508 | 396 | 0.0009 | 41.02 | 7.256 | 0.1774 | 214248.0 | 104000000 | 52400000000 | 27200000000000 | 0.4390 | 0.2040 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0136 | 0.0005 | 0.0498 | 0.0107 | 0.1097 | 0.0237 | 0.1108 | 0.0193 | 0.1486 | 0.0344 | 0.5627 | 0.9113 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0024 | 0.0000 | 0.0058 | 0.0004 | 0.0229 | 0.0095 | 0.0478 | 0.0189 | 0.0484 | 0.0112 | 0.0635 | 0.0227 | 0.8089 | 0.9373 | 0.0050 | 0.0153 | 0.0059 | 0.0153 | 0.0243 | 0.0458 | 0.0703 | 0.1756 | 0.1456 | 0.1221 | 0.1816 | 0.1603 | 0.1364 | 0.0916 | 0.1356 | 0.1069 | 0.2954 | 0.2672 | 0.0019 | 0.0038 | 0.0059 | 0.0261 | 0.0676 | 0.1051 | 0.0997 | 0.1070 | 0.5829 | 5 | 6 | 7 | 9 | 11 | 25 | 76 | 148 | 295 | 0.1599 | 22.17 | 4.036 | 0.5973 | 33837.1 | 18800000 | 12800000000 | 9900000000000 | 0.6360 | 0.0673 | 0.0357 | 0.0021 | 0.1417 | 0.0167 | 0.2200 | 0.0889 | 0.1536 | 0.1271 | 0.1497 | 0.1836 | 0.1249 | 0.1857 | 0.0694 | 0.1130 | 0.0565 | 0.1130 | 0.0486 | 0.1700 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0006 | 0.0003 | 0.0113 | 0.0062 | 0.0430 | 0.0382 | 0.0708 | 0.0689 | 0.0549 | 0.0430 | 0.0815 | 0.0753 | 0.7371 | 0.7679 | 0.0002 | 0.0000 | 0.0005 | 0.0010 | 0.0049 | 0.0052 | 0.0117 | 0.0160 | 0.0608 | 0.0640 | 0.0963 | 0.1006 | 0.0629 | 0.0694 | 0.0974 | 0.1091 | 0.6653 | 0.6349 | 0.0002 | 0.0006 | 0.0023 | 0.0121 | 0.0489 | 0.0886 | 0.0606 | 0.0917 | 0.6949 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1068 | 588 | | 752 | 8804 | 837.7 | 183.87 | 21.91 | 27.10 | 548 | 654 | 750 | 824 | 893 | 932 | 956 | 997 | 1042 | 0.0601 | 529 | 0.815 | 73.00 | 17.00 | 2 | 0.2420 | 182 | 0.0018 | 141.74 | 6.411 | 0.1068 | 735551.0 | 669000000 | 625000000000 | 596000000000000 | 0.3650 | 0.2575 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0029 | 0.0667 | 0.0345 | 0.1644 | 0.0576 | 0.1111 | 0.0273 | 0.1333 | 0.0604 | 0.5156 | 0.8173 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0051 | 0.0029 | 0.0341 | 0.0345 | 0.0631 | 0.0575 | 0.0341 | 0.0273 | 0.0546 | 0.0489 | 0.8089 | 0.8290 | 0.0000 | 1.0000 | 0.0000 | 0.0000 | 0.0147 | 0.0000 | 0.0662 | 0.0000 | 0.1103 | 0.0000 | 0.2132 | 0.0000 | 0.0882 | 0.0000 | 0.1324 | 0.0000 | 0.3750 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0068 | 0.0430 | 0.0724 | 0.0385 | 0.0747 | 0.7647 | 6 | 7 | 9 | 10 | 12 | 15 | 20 | 29 | 49 | 0.1218 | 2.34 | 3.113 | 0.7219 | 1214.4 | 130232 | 20200000 | 4000000000 | 0.4480 | 0.1854 | 0.0474 | 0.0344 | 0.0720 | 0.0374 | 0.1147 | 0.0502 | 0.1735 | 0.0709 | 0.1782 | 0.1115 | 0.1640 | 0.1388 | 0.1393 | 0.1286 | 0.0891 | 0.1916 | 0.0218 | 0.2366 | 0.0077 | 0.0179 | 0.0123 | 0.0163 | 0.0143 | 0.0191 | 0.0299 | 0.0253 | 0.0486 | 0.0447 | 0.0615 | 0.0613 | 0.0745 | 0.0513 | 0.0968 | 0.0970 | 0.6544 | 0.6671 | 0.0067 | 0.0030 | 0.0062 | 0.0085 | 0.0154 | 0.0164 | 0.0308 | 0.0413 | 0.0677 | 0.0735 | 0.0800 | 0.0874 | 0.0830 | 0.0923 | 0.1148 | 0.1148 | 0.5956 | 0.5628 | 0.0045 | 0.0081 | 0.0134 | 0.0292 | 0.0564 | 0.0714 | 0.0673 | 0.1039 | 0.6458 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 724 | | 2796 | 6922 | 1289.3 | 297.81 | 11.57 | 14.75 | 882 | 996 | 1126 | 1218 | 1314 | 1409 | 1473 | 1547 | 1666 | 0.1000 | 692 | 0.449 | 77.06 | 17.03 | 1 | 0.0898 | 251 | 0.0006 | 162.50 | 7.490 | 0.1405 | 1750000.0 | 2480000000 | 3640000000000 | 5.5E+15 | 0.4200 | 0.2151 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0006 | 0.0000 | 0.0150 | 0.0008 | 0.0807 | 0.0218 | 0.1502 | 0.0514 | 0.1120 | 0.0327 | 0.1352 | 0.0510 | 0.5063 | 0.8419 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0004 | 0.0334 | 0.0184 | 0.0621 | 0.0376 | 0.0375 | 0.0192 | 0.0570 | 0.0289 | 0.8086 | 0.8955 | 0.0036 | 0.0000 | 0.0125 | 0.0215 | 0.0179 | 0.0538 | 0.0339 | 0.1075 | 0.1179 | 0.1720 | 0.1732 | 0.2151 | 0.0875 | 0.1183 | 0.1304 | 0.1720 | 0.4232 | 0.1398 | 0.0000 | 0.0000 | 0.0007 | 0.0061 | 0.0509 | 0.1141 | 0.0645 | 0.0971 | 0.6667 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 16 | 0.1442 | 0.50 | 1.438 | 0.5109 | 351.5 | 25544.2 | 2750000 | 377000000 | 0.5711 | 0.1027 | 0.1170 | 0.0291 | 0.1623 | 0.0624 | 0.1857 | 0.0979 | 0.1798 | 0.1155 | 0.1535 | 0.1440 | 0.0892 | 0.1715 | 0.0738 | 0.1552 | 0.0322 | 0.1366 | 0.0066 | 0.0877 | 0.0708 | 0.0240 | 0.0893 | 0.0506 | 0.0777 | 0.0776 | 0.0796 | 0.0886 | 0.0949 | 0.1002 | 0.0888 | 0.1140 | 0.1000 | 0.1166 | 0.1124 | 0.1369 | 0.2864 | 0.2915 | 0.0290 | 0.0090 | 0.0139 | 0.0030 | 0.0189 | 0.0060 | 0.0391 | 0.0571 | 0.1009 | 0.1141 | 0.1072 | 0.1096 | 0.0971 | 0.1096 | 0.1299 | 0.1276 | 0.4641 | 0.4640 | 0.0730 | 0.0589 | 0.0518 | 0.0754 | 0.0761 | 0.0934 | 0.1013 | 0.0879 | 0.3823 |
| SK-BR-3 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 961 | 83 | | 2742 | 10295 | 256.4 | 210.99 | 5.84 | 2.73 | 85 | 107 | 125 | 146 | 174 | 205 | 260 | 375 | 620 | 0.0768 | 791 | 0.892 | 36.22 | 8.60 | 0 | 0.0317 | 87 | 0.0014 | 48.21 | 6.944 | 0.2535 | 110231.0 | 65700000 | 45700000000 | 34200000000000 | 0.3023 | 0.3121 | 0.0000 | 0.0000 | 0.0068 | 0.0000 | 0.0091 | 0.0000 | 0.0590 | 0.0149 | 0.1791 | 0.0528 | 0.1655 | 0.0916 | 0.1179 | 0.0677 | 0.1088 | 0.1066 | 0.3537 | 0.6663 | 0.0000 | 0.0000 | 0.0027 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0076 | 0.0370 | 0.0242 | 0.0497 | 0.0369 | 0.0416 | 0.0242 | 0.0542 | 0.0445 | 0.8076 | 0.8626 | 0.0015 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0075 | 0.0070 | 0.0330 | 0.0370 | 0.0526 | 0.0546 | 0.0330 | 0.0352 | 0.0691 | 0.0651 | 0.8018 | 0.8011 | 0.0012 | 0.0012 | 0.0000 | 0.0059 | 0.0297 | 0.0547 | 0.0321 | 0.0523 | 0.8228 | 2 | 4 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 0.0175 | 13.89 | 4.460 | 0.2950 | 41.5 | 339.783 | 3128.09 | 31961.6 | 0.5476 | 0.1416 | 0.0210 | 0.0022 | 0.0924 | 0.0062 | 0.1853 | 0.0333 | 0.2319 | 0.0823 | 0.2233 | 0.1544 | 0.1561 | 0.2425 | 0.0700 | 0.2497 | 0.0170 | 0.1701 | 0.0030 | 0.0593 | 0.0012 | 0.0000 | 0.0080 | 0.0010 | 0.0371 | 0.0068 | 0.0981 | 0.0266 | 0.1836 | 0.0573 | 0.2370 | 0.1201 | 0.2176 | 0.2178 | 0.1428 | 0.3119 | 0.0746 | 0.2586 | 0.1311 | 0.2667 | 0.2100 | 0.2515 | 0.2092 | 0.1673 | 0.1698 | 0.1115 | 0.1054 | 0.0630 | 0.0671 | 0.0527 | 0.0519 | 0.0333 | 0.0371 | 0.0339 | 0.0183 | 0.0200 | 0.0124 | 0.0502 | 0.1000 | 0.1483 | 0.1892 | 0.1839 | 0.1558 | 0.0989 | 0.0613 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1130 | 460 | | 653 | 578 | 83.3 | 9.22 | 65.56 | 101.38 | 71 | 74 | 78 | 80 | 83 | 86 | 89 | 92 | 95 | 0.3910 | 226 | 0.478 | 77.79 | 11.31 | 1 | 0.3155 | 206 | 0.1159 | 0.55 | 2.394 | 0.7678 | 7017.7 | 598559 | 51600000 | 4510000000 | 0.4222 | 0.2132 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0065 | 0.0015 | 0.0455 | 0.0352 | 0.0698 | 0.0674 | 0.0779 | 0.0260 | 0.1347 | 0.0475 | 0.6623 | 0.8224 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0047 | 0.0015 | 0.0376 | 0.0352 | 0.0610 | 0.0674 | 0.0297 | 0.0260 | 0.0563 | 0.0475 | 0.8075 | 0.8224 | 0.1304 | 0.0000 | 0.3478 | 0.0000 | 0.2174 | 0.0000 | 0.1304 | 0.0000 | 0.0870 | 0.0000 | 0.0435 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0151 | 0.0211 | 0.0452 | 0.0994 | 0.0964 | 0.1325 | 0.1687 | 0.4187 | 7 | 10 | 13 | 18 | 24 | 35 | 52 | 90 | 200 | 0.0809 | 31.27 | 3.431 | 0.5091 | 14559.2 | 5410000 | 2520000000 | 1320000000000 | 0.5610 | 0.0846 | 0.2727 | 0.0094 | 0.5000 | 0.0377 | 0.2273 | 0.4151 | 0.0000 | 0.3396 | 0.0000 | 0.1038 | 0.0000 | 0.0849 | 0.0000 | 0.0094 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0046 | 0.0405 | 0.0091 | 0.0173 | 0.0274 | 0.0347 | 0.0365 | 0.2023 | 0.1507 | 0.3410 | 0.3196 | 0.1676 | 0.1553 | 0.1850 | 0.1918 | 0.0116 | 0.1050 | 0.0155 | 0.0177 | 0.0233 | 0.0265 | 0.0698 | 0.0885 | 0.0853 | 0.0619 | 0.2636 | 0.3894 | 0.3488 | 0.3009 | 0.1860 | 0.1150 | 0.0078 | 0.0000 | 0.0000 | 0.0000 | 0.0134 | 0.0201 | 0.0336 | 0.0336 | 0.2282 | 0.3758 | 0.2013 | 0.0940 | 0.0000 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 798 | 428 | | 27432 | 45118 | 211.1 | 59.97 | 98.82 | 173.21 | 140 | 162 | 179 | 194 | 208 | 223 | 239 | 258 | 287 | 0.0427 | 1927 | 0.804 | 104.04 | 21.19 | 1 | 0.0082 | 226 | 0.0007 | 43.54 | 7.545 | 0.1862 | 48158.5 | 11800000 | 3050000000 | 838000000000 | 0.4170 | 0.2298 | 0.0009 | 0.0000 | 0.0014 | 0.0001 | 0.0072 | 0.0005 | 0.0254 | 0.0026 | 0.0661 | 0.0188 | 0.1224 | 0.0410 | 0.1361 | 0.0439 | 0.1737 | 0.0674 | 0.4667 | 0.8259 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0001 | 0.0072 | 0.0009 | 0.0239 | 0.0093 | 0.0448 | 0.0189 | 0.0494 | 0.0177 | 0.0650 | 0.0292 | 0.8061 | 0.9239 | 0.0049 | 0.0049 | 0.0082 | 0.0175 | 0.0196 | 0.0265 | 0.0469 | 0.0746 | 0.0894 | 0.1169 | 0.1266 | 0.1677 | 0.1090 | 0.1102 | 0.1271 | 0.1250 | 0.4683 | 0.3566 | 0.0014 | 0.0023 | 0.0066 | 0.0227 | 0.0535 | 0.0917 | 0.0877 | 0.1135 | 0.6206 | 10 | 12 | 14 | 16 | 20 | 29 | 54 | 137 | 332 | 0.1819 | 23.17 | 3.891 | 0.6587 | 39767.1 | 24100000 | 17400000000 | 14100000000000 | 0.4082 | 0.2647 | 0.1462 | 0.0039 | 0.3078 | 0.0465 | 0.2795 | 0.2378 | 0.1040 | 0.2151 | 0.0818 | 0.2042 | 0.0463 | 0.1441 | 0.0206 | 0.0647 | 0.0093 | 0.0494 | 0.0046 | 0.0343 | 0.0000 | 0.0000 | 0.0009 | 0.0006 | 0.0015 | 0.0011 | 0.0142 | 0.0095 | 0.0704 | 0.0604 | 0.0987 | 0.0930 | 0.0678 | 0.0551 | 0.1104 | 0.0943 | 0.6360 | 0.6860 | 0.0003 | 0.0000 | 0.0017 | 0.0017 | 0.0033 | 0.0043 | 0.0185 | 0.0216 | 0.0848 | 0.0897 | 0.1211 | 0.1251 | 0.0804 | 0.0863 | 0.1188 | 0.1212 | 0.5710 | 0.5502 | 0.0001 | 0.0006 | 0.0030 | 0.0167 | 0.0751 | 0.1185 | 0.0740 | 0.1117 | 0.6002 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 312 | 733 | | 7233 | 20217 | 523.9 | 88.32 | 192.73 | 354.08 | 412 | 444 | 470 | 496 | 519 | 544 | 571 | 604 | 641 | 0.0504 | 1018 | 1.154 | 114.98 | 42.58 | 1 | 0.0408 | 295 | 0.0018 | 19.88 | 6.575 | 0.2459 | 282245.0 | 156000000 | 88600000000 | 51500000000000 | 0.4172 | 0.2311 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0003 | 0.0114 | 0.0004 | 0.0461 | 0.0113 | 0.0920 | 0.0228 | 0.1143 | 0.0150 | 0.1514 | 0.0291 | 0.5824 | 0.9210 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0046 | 0.0001 | 0.0219 | 0.0096 | 0.0442 | 0.0195 | 0.0517 | 0.0096 | 0.0720 | 0.0186 | 0.8052 | 0.9427 | 0.0032 | 0.0494 | 0.0085 | 0.0247 | 0.0481 | 0.0617 | 0.1068 | 0.2099 | 0.1474 | 0.1481 | 0.1699 | 0.1728 | 0.1453 | 0.1605 | 0.1271 | 0.1111 | 0.2436 | 0.0617 | 0.0014 | 0.0026 | 0.0072 | 0.0203 | 0.0629 | 0.1090 | 0.0973 | 0.1296 | 0.5697 | 10 | 12 | 14 | 16 | 19 | 32 | 110 | 339 | 644 | 0.1456 | 63.21 | 4.433 | 0.6015 | 162507.0 | 200000000 | 303000000000 | 525000000000000 | 0.5064 | 0.1533 | 0.1318 | 0.0049 | 0.3100 | 0.0323 | 0.3324 | 0.2391 | 0.1234 | 0.2742 | 0.0561 | 0.2167 | 0.0351 | 0.1220 | 0.0042 | 0.0617 | 0.0056 | 0.0358 | 0.0014 | 0.0133 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0005 | 0.0003 | 0.0070 | 0.0065 | 0.0491 | 0.0410 | 0.0772 | 0.0740 | 0.0498 | 0.0478 | 0.0813 | 0.0702 | 0.7351 | 0.7600 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0004 | 0.0017 | 0.0119 | 0.0114 | 0.0544 | 0.0623 | 0.0908 | 0.0925 | 0.0634 | 0.0717 | 0.0934 | 0.1071 | 0.6854 | 0.6531 | 0.0000 | 0.0002 | 0.0008 | 0.0084 | 0.0511 | 0.0851 | 0.0532 | 0.0876 | 0.7136 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 602 | 376 | | 1156 | 4064 | 474.2 | 143.37 | 10.35 | 8.30 | 315 | 334 | 360 | 391 | 431 | 490 | 562 | 644 | 697 | 0.0947 | 385 | 1.114 | 51.86 | 18.44 | 1 | 0.1211 | 140 | 0.0033 | 11.41 | 6.019 | 0.2906 | 245360.0 | 137000000 | 81700000000 | 51000000000000 | 0.3632 | 0.2648 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0025 | 0.0010 | 0.0327 | 0.0031 | 0.0955 | 0.0462 | 0.1382 | 0.0776 | 0.1709 | 0.0525 | 0.1608 | 0.0860 | 0.3995 | 0.7324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0009 | 0.0136 | 0.0017 | 0.0339 | 0.0304 | 0.0434 | 0.0470 | 0.0542 | 0.0261 | 0.0488 | 0.0487 | 0.8049 | 0.8452 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0118 | 0.0152 | 0.0559 | 0.0812 | 0.0588 | 0.0812 | 0.0559 | 0.0558 | 0.0765 | 0.1269 | 0.7412 | 0.6396 | 0.0000 | 0.0000 | 0.0000 | 0.0041 | 0.0412 | 0.0741 | 0.0329 | 0.0658 | 0.7819 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 15 | 0.0098 | 16.68 | 5.103 | 0.3379 | 176.1 | 6409.85 | 409709 | 33400000 | 0.4040 | 0.2136 | 0.0440 | 0.0038 | 0.1040 | 0.0105 | 0.1253 | 0.0332 | 0.2015 | 0.0514 | 0.2154 | 0.0867 | 0.1685 | 0.1160 | 0.1026 | 0.1499 | 0.0330 | 0.2376 | 0.0059 | 0.3110 | 0.0174 | 0.0014 | 0.0349 | 0.0052 | 0.0418 | 0.0193 | 0.0499 | 0.0293 | 0.0774 | 0.0503 | 0.1078 | 0.0748 | 0.1139 | 0.0871 | 0.1390 | 0.1550 | 0.4179 | 0.5775 | 0.0490 | 0.0472 | 0.0672 | 0.0407 | 0.0608 | 0.0650 | 0.0572 | 0.0911 | 0.0762 | 0.1382 | 0.1016 | 0.1154 | 0.1143 | 0.1073 | 0.1661 | 0.1268 | 0.3076 | 0.2683 | 0.0357 | 0.0421 | 0.0562 | 0.0761 | 0.0860 | 0.1094 | 0.1018 | 0.1281 | 0.3645 |