High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 525 | 784 | | 306 | 3162 | 64.0 | 11.66 | 117.65 | 178.73 | 49 | 52 | 58 | 61 | 64 | 67 | 70 | 74 | 79 | 0.1395 | 441 | 1.153 | 68.73 | 23.77 | 1 | 0.5556 | 170 | 0.0077 | 10.17 | 5.047 | 0.3110 | 4226.0 | 287862 | 20200000 | 1450000000 | 0.4562 | 0.1761 | 0.0000 | 0.0000 | 0.0147 | 0.0033 | 0.0196 | 0.0000 | 0.0686 | 0.0133 | 0.1520 | 0.0365 | 0.1765 | 0.1794 | 0.1520 | 0.0332 | 0.1912 | 0.1296 | 0.2255 | 0.6047 | 0.0000 | 0.0000 | 0.0118 | 0.0033 | 0.0039 | 0.0000 | 0.0433 | 0.0131 | 0.0630 | 0.0359 | 0.1299 | 0.1634 | 0.0591 | 0.0327 | 0.1378 | 0.0882 | 0.5512 | 0.6634 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0800 | 0.0000 | 0.0600 | 0.8000 | 0.2200 | 0.2000 | 0.2000 | 0.0000 | 0.1400 | 0.0000 | 0.1400 | 0.0000 | 0.1200 | 0.0000 | 0.0062 | 0.0124 | 0.0248 | 0.0559 | 0.1242 | 0.0994 | 0.1242 | 0.1180 | 0.4348 | 11 | 12 | 13 | 15 | 18 | 44 | 106 | 220 | 400 | 0.1851 | 37.34 | 4.002 | 0.6018 | 45776.0 | 25200000 | 16900000000 | 13200000000000 | 0.6720 | 0.0567 | 0.1282 | 0.0081 | 0.1949 | 0.0782 | 0.2513 | 0.1240 | 0.1179 | 0.1563 | 0.1128 | 0.1725 | 0.0667 | 0.1590 | 0.0359 | 0.0755 | 0.0359 | 0.0916 | 0.0564 | 0.1348 | 0.0010 | 0.0000 | 0.0010 | 0.0009 | 0.0040 | 0.0027 | 0.0210 | 0.0153 | 0.0791 | 0.0694 | 0.1351 | 0.1127 | 0.1011 | 0.0902 | 0.1592 | 0.1461 | 0.4985 | 0.5627 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0012 | 0.0054 | 0.0348 | 0.0312 | 0.1057 | 0.1098 | 0.1480 | 0.1707 | 0.1294 | 0.1328 | 0.1654 | 0.1667 | 0.4142 | 0.3821 | 0.0011 | 0.0000 | 0.0033 | 0.0255 | 0.0909 | 0.1408 | 0.1098 | 0.1663 | 0.4623 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 374 | 827 | | 538 | 5755 | 91.8 | 48.44 | 171.54 | 297.95 | 29 | 40 | 57 | 74 | 89 | 101 | 116 | 140 | 161 | 0.0895 | 515 | 1.275 | 31.62 | 12.17 | 2 | 0.1543 | 83 | 0.0025 | 70.15 | 6.080 | 0.1560 | 10772.9 | 1460000 | 216000000 | 34000000000 | 0.3272 | 0.2735 | 0.0000 | 0.0000 | 0.0282 | 0.0000 | 0.1338 | 0.0000 | 0.1901 | 0.0198 | 0.1620 | 0.1581 | 0.1268 | 0.1937 | 0.1479 | 0.1621 | 0.1056 | 0.1581 | 0.1056 | 0.3083 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0031 | 0.0131 | 0.0800 | 0.0551 | 0.0985 | 0.0866 | 0.0431 | 0.0525 | 0.1138 | 0.0840 | 0.6585 | 0.7087 | 0.0000 | 0.0000 | 0.0000 | 0.0156 | 0.0055 | 0.0000 | 0.0383 | 0.0156 | 0.1038 | 0.1328 | 0.1038 | 0.1016 | 0.1093 | 0.1016 | 0.1421 | 0.1328 | 0.4973 | 0.5000 | 0.0000 | 0.0000 | 0.0078 | 0.0389 | 0.0661 | 0.1128 | 0.0973 | 0.1128 | 0.5642 | 17 | 19 | 20 | 22 | 25 | 35 | 92 | 249 | 645 | 0.1812 | 27.53 | 3.742 | 0.6466 | 118185.0 | 112000000 | 119000000000 | 139000000000000 | 0.7250 | 0.0477 | 0.0600 | 0.0080 | 0.2240 | 0.0282 | 0.3600 | 0.1690 | 0.1600 | 0.1932 | 0.0920 | 0.2012 | 0.0480 | 0.1469 | 0.0240 | 0.1066 | 0.0240 | 0.0624 | 0.0080 | 0.0845 | 0.0000 | 0.0000 | 0.0007 | 0.0006 | 0.0020 | 0.0012 | 0.0231 | 0.0168 | 0.0909 | 0.0895 | 0.1324 | 0.1111 | 0.0856 | 0.0847 | 0.1232 | 0.1219 | 0.5422 | 0.5742 | 0.0000 | 0.0000 | 0.0047 | 0.0060 | 0.0087 | 0.0146 | 0.0379 | 0.0368 | 0.0883 | 0.0856 | 0.1270 | 0.1336 | 0.1017 | 0.0967 | 0.1222 | 0.1182 | 0.5095 | 0.5086 | 0.0000 | 0.0000 | 0.0086 | 0.0281 | 0.0944 | 0.1354 | 0.0929 | 0.1218 | 0.5187 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 658 | 168 | | 403 | 1766 | 68.5 | 19.76 | 7.99 | 2.37 | 49 | 53 | 56 | 59 | 63 | 70 | 74 | 85 | 98 | 0.1750 | 309 | 1.167 | 34.83 | 13.34 | 1 | 0.2258 | 91 | 0.0533 | 1.76 | 3.525 | 0.6505 | 5083.4 | 408505 | 35400000 | 3290000000 | 0.4186 | 0.2106 | 0.0050 | 0.0000 | 0.0347 | 0.0029 | 0.1139 | 0.0233 | 0.1139 | 0.0437 | 0.1386 | 0.0962 | 0.1238 | 0.1895 | 0.1386 | 0.1137 | 0.1238 | 0.1429 | 0.2079 | 0.3878 | 0.0034 | 0.0000 | 0.0103 | 0.0000 | 0.0206 | 0.0052 | 0.0412 | 0.0129 | 0.1237 | 0.0722 | 0.1340 | 0.1727 | 0.0790 | 0.0851 | 0.0962 | 0.1134 | 0.4914 | 0.5387 | 0.0112 | 0.0000 | 0.0112 | 0.0000 | 0.0000 | 0.0667 | 0.1236 | 0.2444 | 0.1685 | 0.2222 | 0.2360 | 0.2667 | 0.0787 | 0.0222 | 0.1461 | 0.0667 | 0.2247 | 0.1111 | 0.0000 | 0.0000 | 0.0117 | 0.0526 | 0.1287 | 0.1988 | 0.0877 | 0.1345 | 0.3860 | 5 | 6 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0170 | 10.27 | 4.413 | 0.3266 | 69.5 | 648.007 | 6410.02 | 66817.3 | 0.4806 | 0.1782 | 0.0225 | 0.0013 | 0.0688 | 0.0040 | 0.1865 | 0.0092 | 0.2678 | 0.0257 | 0.2240 | 0.0870 | 0.1502 | 0.1087 | 0.0601 | 0.1963 | 0.0138 | 0.3057 | 0.0063 | 0.2622 | 0.0049 | 0.0000 | 0.0154 | 0.0018 | 0.0561 | 0.0054 | 0.0829 | 0.0127 | 0.1488 | 0.0647 | 0.1715 | 0.0810 | 0.1837 | 0.0906 | 0.2179 | 0.2502 | 0.1187 | 0.4937 | 0.1230 | 0.3869 | 0.2181 | 0.2993 | 0.2645 | 0.1314 | 0.1763 | 0.1314 | 0.1137 | 0.0292 | 0.0650 | 0.0219 | 0.0232 | 0.0000 | 0.0139 | 0.0000 | 0.0023 | 0.0000 | 0.0089 | 0.0445 | 0.0870 | 0.1235 | 0.1966 | 0.2184 | 0.1601 | 0.1235 | 0.0375 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1201 | 147 | | 25401 | 21792 | 80.3 | 36.47 | 7.79 | 3.16 | 47 | 51 | 55 | 60 | 67 | 79 | 95 | 111 | 130 | 0.0646 | 1407 | 0.643 | 109.48 | 22.02 | 3 | 0.0122 | 311 | 0.0238 | 1.54 | 4.339 | 0.6433 | 7784.7 | 930349 | 141000000 | 27400000000 | 0.3746 | 0.2574 | 0.0183 | 0.0041 | 0.0285 | 0.0101 | 0.0332 | 0.0165 | 0.0445 | 0.0216 | 0.0579 | 0.0307 | 0.0760 | 0.0454 | 0.0991 | 0.0645 | 0.1547 | 0.1011 | 0.4878 | 0.7059 | 0.0063 | 0.0025 | 0.0088 | 0.0051 | 0.0101 | 0.0093 | 0.0128 | 0.0127 | 0.0158 | 0.0171 | 0.0202 | 0.0254 | 0.0263 | 0.0353 | 0.0450 | 0.0545 | 0.8547 | 0.8381 | 0.0029 | 0.0096 | 0.0051 | 0.0076 | 0.0087 | 0.0135 | 0.0154 | 0.0237 | 0.0181 | 0.0317 | 0.0252 | 0.0416 | 0.0356 | 0.0590 | 0.0614 | 0.0833 | 0.8277 | 0.7300 | 0.0039 | 0.0045 | 0.0066 | 0.0106 | 0.0121 | 0.0194 | 0.0250 | 0.0402 | 0.8777 | 4 | 5 | 6 | 7 | 8 | 9 | 9 | 10 | 12 | 0.3288 | 0.54 | 1.489 | 0.7679 | 70.7 | 710.738 | 7758.34 | 90867.1 | 0.5651 | 0.1468 | 0.0276 | 0.0002 | 0.1012 | 0.0027 | 0.1830 | 0.0162 | 0.2395 | 0.0448 | 0.2232 | 0.1065 | 0.1440 | 0.1983 | 0.0622 | 0.2724 | 0.0175 | 0.2494 | 0.0018 | 0.1095 | 0.0011 | 0.0001 | 0.0095 | 0.0007 | 0.0313 | 0.0047 | 0.0743 | 0.0148 | 0.1392 | 0.0405 | 0.2209 | 0.1002 | 0.2544 | 0.1989 | 0.1985 | 0.3291 | 0.0707 | 0.3109 | 0.0837 | 0.3817 | 0.2220 | 0.3524 | 0.2715 | 0.1695 | 0.2102 | 0.0699 | 0.1317 | 0.0232 | 0.0547 | 0.0028 | 0.0218 | 0.0004 | 0.0035 | 0.0000 | 0.0010 | 0.0000 | 0.0061 | 0.0422 | 0.1149 | 0.1974 | 0.2403 | 0.2128 | 0.1308 | 0.0484 | 0.0072 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 972 | 177 | | 395 | 12546 | 117.2 | 19.48 | 22.21 | 93.56 | 93 | 98 | 104 | 109 | 113 | 121 | 128 | 137 | 146 | 0.0524 | 657 | 1.105 | 42.05 | 12.04 | 0 | 0.2380 | 94 | 0.0471 | 0.93 | 3.300 | 0.6696 | 14103.0 | 1740000 | 221000000 | 28700000000 | 0.3949 | 0.2407 | 0.0000 | 0.0000 | 0.0102 | 0.0000 | 0.0136 | 0.0000 | 0.0374 | 0.0127 | 0.0646 | 0.0433 | 0.1224 | 0.0738 | 0.1327 | 0.0585 | 0.1565 | 0.0916 | 0.4626 | 0.7201 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0085 | 0.0000 | 0.0254 | 0.0127 | 0.0366 | 0.0430 | 0.0732 | 0.0734 | 0.0704 | 0.0532 | 0.0789 | 0.0658 | 0.7042 | 0.7519 | 0.0000 | 0.0000 | 0.0164 | 1.0000 | 0.0492 | 0.0000 | 0.0820 | 0.0000 | 0.0984 | 0.0000 | 0.1639 | 0.0000 | 0.1148 | 0.0000 | 0.1967 | 0.0000 | 0.2787 | 0.0000 | 0.0055 | 0.0055 | 0.0000 | 0.0497 | 0.0552 | 0.0718 | 0.0939 | 0.0939 | 0.6243 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 14 | 0.1205 | 3.55 | 1.534 | 0.4274 | 9246.7 | 8900000 | 10500000000 | 13500000000000 | 0.4645 | 0.1926 | 0.0604 | 0.1758 | 0.1758 | 0.0687 | 0.2582 | 0.0929 | 0.3462 | 0.1414 | 0.1099 | 0.1980 | 0.0385 | 0.1737 | 0.0110 | 0.0747 | 0.0000 | 0.0485 | 0.0000 | 0.0263 | 0.0000 | 0.0672 | 0.0020 | 0.0227 | 0.0099 | 0.0180 | 0.0159 | 0.0164 | 0.0556 | 0.0469 | 0.0724 | 0.0618 | 0.0764 | 0.0641 | 0.1022 | 0.0821 | 0.6657 | 0.6208 | 0.0024 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0026 | 0.0182 | 0.0140 | 0.0654 | 0.0727 | 0.0956 | 0.0969 | 0.0690 | 0.0625 | 0.0920 | 0.0982 | 0.6550 | 0.6531 | 0.0000 | 0.0022 | 0.0065 | 0.0196 | 0.0577 | 0.0882 | 0.0719 | 0.0882 | 0.6656 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 688 | 317 | | 634 | 1912 | 61.1 | 11.51 | 6.65 | 2.29 | 51 | 53 | 55 | 57 | 59 | 62 | 64 | 67 | 72 | 0.1815 | 347 | 0.352 | 32.70 | 5.39 | 1 | 0.1893 | 120 | 0.1030 | 0.83 | 2.651 | 0.7146 | 3861.0 | 255798 | 18100000 | 1380000000 | 0.3514 | 0.2723 | 0.0000 | 0.0000 | 0.0055 | 0.0000 | 0.0147 | 0.0049 | 0.0257 | 0.0180 | 0.0754 | 0.0377 | 0.1471 | 0.1361 | 0.0901 | 0.0656 | 0.1746 | 0.0885 | 0.4669 | 0.6492 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0117 | 0.0016 | 0.0167 | 0.0126 | 0.0552 | 0.0379 | 0.1154 | 0.1183 | 0.0635 | 0.0473 | 0.1338 | 0.0804 | 0.6020 | 0.7019 | 0.0185 | 0.0000 | 0.0000 | 0.0000 | 0.1111 | 0.0000 | 0.0741 | 0.2500 | 0.1852 | 0.1667 | 0.1852 | 0.3333 | 0.1111 | 0.0000 | 0.0741 | 0.0833 | 0.2407 | 0.1667 | 0.0071 | 0.0179 | 0.0214 | 0.0750 | 0.1571 | 0.1607 | 0.1750 | 0.1321 | 0.2536 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 8 | 10 | 0.0192 | 7.74 | 4.309 | 0.3727 | 49.5 | 405.119 | 3603.71 | 34564.2 | 0.5192 | 0.1236 | 0.0276 | 0.0014 | 0.1166 | 0.0113 | 0.1899 | 0.0346 | 0.2067 | 0.0720 | 0.2067 | 0.1200 | 0.1322 | 0.1962 | 0.0745 | 0.2392 | 0.0397 | 0.2188 | 0.0060 | 0.1066 | 0.0107 | 0.0006 | 0.0471 | 0.0074 | 0.0661 | 0.0135 | 0.1033 | 0.0418 | 0.1281 | 0.0811 | 0.1702 | 0.1345 | 0.1860 | 0.1499 | 0.1570 | 0.2500 | 0.1314 | 0.3213 | 0.1296 | 0.2038 | 0.1640 | 0.2464 | 0.2275 | 0.2512 | 0.1772 | 0.1706 | 0.1296 | 0.0569 | 0.1032 | 0.0474 | 0.0423 | 0.0237 | 0.0265 | 0.0000 | 0.0000 | 0.0000 | 0.0322 | 0.0665 | 0.1104 | 0.1179 | 0.1533 | 0.1608 | 0.1554 | 0.1222 | 0.0815 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 897 | 352 | | 491 | 10165 | 31.2 | 10.66 | 5.57 | 2.04 | 21 | 23 | 24 | 26 | 27 | 30 | 34 | 40 | 49 | 0.0858 | 872 | 0.813 | 87.21 | 20.59 | 5 | 0.4073 | 200 | 0.0618 | 0.76 | 3.150 | 0.6872 | 1083.9 | 42132.6 | 1810000 | 83600000 | 0.3481 | 0.2731 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0187 | 0.0025 | 0.0561 | 0.0150 | 0.1168 | 0.0848 | 0.2336 | 0.0798 | 0.1963 | 0.0873 | 0.1869 | 0.1446 | 0.1729 | 0.5860 | 0.0061 | 0.0000 | 0.0061 | 0.0000 | 0.0122 | 0.0021 | 0.0334 | 0.0125 | 0.0608 | 0.0582 | 0.0912 | 0.0353 | 0.0821 | 0.0561 | 0.1003 | 0.0811 | 0.6079 | 0.7547 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0348 | 0.0625 | 0.0609 | 0.0500 | 0.1391 | 0.1625 | 0.0609 | 0.1125 | 0.1043 | 0.0750 | 0.6000 | 0.5375 | 0.0000 | 0.0107 | 0.0000 | 0.0481 | 0.0428 | 0.1070 | 0.0695 | 0.1016 | 0.6203 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0061 | 0.11 | 0.381 | 0.0699 | 35.2 | 247.481 | 1925.98 | 16644.2 | 0.5163 | 0.1494 | 0.0075 | 0.0004 | 0.0317 | 0.0014 | 0.1096 | 0.0083 | 0.1889 | 0.0233 | 0.2557 | 0.0515 | 0.2310 | 0.1180 | 0.1247 | 0.2326 | 0.0447 | 0.3477 | 0.0060 | 0.2168 | 0.0016 | 0.0000 | 0.0075 | 0.0002 | 0.0348 | 0.0045 | 0.0908 | 0.0154 | 0.1571 | 0.0325 | 0.2323 | 0.0692 | 0.2275 | 0.1499 | 0.1597 | 0.3269 | 0.0887 | 0.4014 | 0.2469 | 0.4372 | 0.2984 | 0.2271 | 0.1850 | 0.0804 | 0.0888 | 0.0635 | 0.0564 | 0.0536 | 0.0355 | 0.0409 | 0.0392 | 0.0381 | 0.0282 | 0.0381 | 0.0214 | 0.0212 | 0.0197 | 0.0760 | 0.1532 | 0.2101 | 0.1844 | 0.1602 | 0.1001 | 0.0600 | 0.0363 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 835 | 674 | | 1286 | 9006 | 107.9 | 35.92 | 236.20 | 179.35 | 71 | 83 | 90 | 96 | 102 | 108 | 115 | 126 | 148 | 0.0815 | 734 | 0.834 | 60.64 | 18.97 | 2 | 0.1260 | 162 | 0.0037 | 21.25 | 5.914 | 0.2852 | 12925.5 | 1750000 | 272000000 | 48100000000 | 0.4873 | 0.1534 | 0.0027 | 0.0000 | 0.0054 | 0.0036 | 0.0308 | 0.0055 | 0.0496 | 0.0173 | 0.1300 | 0.0656 | 0.1662 | 0.0911 | 0.1421 | 0.0647 | 0.1568 | 0.1047 | 0.3164 | 0.6475 | 0.0000 | 0.0000 | 0.0031 | 0.0016 | 0.0134 | 0.0033 | 0.0237 | 0.0124 | 0.0792 | 0.0437 | 0.1132 | 0.0766 | 0.0792 | 0.0445 | 0.1091 | 0.0807 | 0.5792 | 0.7372 | 0.0088 | 0.0086 | 0.0088 | 0.0172 | 0.0265 | 0.0172 | 0.0929 | 0.0862 | 0.1106 | 0.1034 | 0.1593 | 0.1724 | 0.0885 | 0.0690 | 0.1283 | 0.1379 | 0.3761 | 0.3879 | 0.0038 | 0.0095 | 0.0302 | 0.0624 | 0.1078 | 0.1229 | 0.1096 | 0.1153 | 0.4386 | 21 | 54 | 101 | 156 | 212 | 269 | 324 | 398 | 492 | 0.0054 | 44.25 | 6.916 | 0.2857 | 87951.8 | 39600000 | 20100000000 | 11200000000000 | 0.5258 | 0.1424 | 0.0084 | 0.0013 | 0.0560 | 0.0023 | 0.1925 | 0.0179 | 0.2183 | 0.0737 | 0.2022 | 0.1661 | 0.1481 | 0.2268 | 0.0959 | 0.1657 | 0.0541 | 0.1561 | 0.0245 | 0.1900 | 0.0002 | 0.0002 | 0.0010 | 0.0009 | 0.0047 | 0.0025 | 0.0137 | 0.0101 | 0.0490 | 0.0402 | 0.0890 | 0.0809 | 0.0733 | 0.0592 | 0.1002 | 0.0870 | 0.6689 | 0.7190 | 0.0012 | 0.0019 | 0.0030 | 0.0054 | 0.0075 | 0.0103 | 0.0251 | 0.0387 | 0.0681 | 0.0831 | 0.1282 | 0.1543 | 0.1091 | 0.1091 | 0.1372 | 0.1313 | 0.5206 | 0.4659 | 0.0007 | 0.0036 | 0.0053 | 0.0177 | 0.0540 | 0.1087 | 0.0856 | 0.1201 | 0.6042 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1041 | 916 | | 403 | 1181 | 80.5 | 10.16 | 173.50 | 253.63 | 67 | 70 | 74 | 77 | 80 | 84 | 86 | 90 | 94 | 0.2320 | 274 | 1.030 | 30.08 | 8.00 | 0 | 0.1762 | 71 | 0.1226 | 0.50 | 2.391 | 0.7876 | 6578.3 | 546175 | 46000000 | 3940000000 | 0.3807 | 0.2394 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0188 | 0.0124 | 0.0591 | 0.0422 | 0.1237 | 0.1166 | 0.1022 | 0.0422 | 0.1532 | 0.0794 | 0.5376 | 0.7072 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0176 | 0.0124 | 0.0403 | 0.0422 | 0.1159 | 0.1166 | 0.0554 | 0.0422 | 0.0781 | 0.0794 | 0.6902 | 0.7072 | 0.0800 | 0.0000 | 0.0800 | 0.0000 | 0.0000 | 0.0000 | 0.2000 | 0.0000 | 0.1200 | 0.0000 | 0.0800 | 0.0000 | 0.2000 | 0.0000 | 0.2000 | 0.0000 | 0.0400 | 0.0000 | 0.0048 | 0.0000 | 0.0144 | 0.0383 | 0.1005 | 0.1340 | 0.0861 | 0.1627 | 0.4593 | 19 | 27 | 36 | 48 | 66 | 100 | 161 | 254 | 474 | 0.0380 | 54.53 | 4.632 | 0.4971 | 94375.3 | 84600000 | 95200000000 | 121000000000000 | 0.4414 | 0.1907 | 0.1038 | 0.0045 | 0.2264 | 0.0588 | 0.2170 | 0.1810 | 0.0472 | 0.1267 | 0.1415 | 0.2262 | 0.1321 | 0.1765 | 0.0943 | 0.0679 | 0.0189 | 0.0498 | 0.0189 | 0.1086 | 0.0000 | 0.0000 | 0.0026 | 0.0021 | 0.0026 | 0.0043 | 0.0490 | 0.0322 | 0.1108 | 0.1052 | 0.2010 | 0.1824 | 0.1031 | 0.0966 | 0.1237 | 0.1223 | 0.4072 | 0.4549 | 0.0035 | 0.0041 | 0.0142 | 0.0122 | 0.0284 | 0.0245 | 0.0674 | 0.0531 | 0.1418 | 0.1633 | 0.1596 | 0.1633 | 0.0887 | 0.0939 | 0.1348 | 0.1347 | 0.3617 | 0.3510 | 0.0030 | 0.0030 | 0.0119 | 0.0625 | 0.1310 | 0.1964 | 0.0923 | 0.1190 | 0.3810 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 695 | 131 | | 413 | 5107 | 82.1 | 20.31 | 279.73 | 253.72 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 98 | 113 | 0.0832 | 425 | 0.434 | 131.03 | 25.55 | 1 | 1.0266 | 424 | 0.0060 | 18.02 | 5.295 | 0.2565 | 7150.1 | 660661 | 64600000 | 6650000000 | 0.4371 | 0.1916 | 0.0042 | 0.0027 | 0.0042 | 0.0000 | 0.0333 | 0.0027 | 0.0667 | 0.0239 | 0.2042 | 0.0557 | 0.1708 | 0.1326 | 0.1708 | 0.0849 | 0.1667 | 0.1618 | 0.1792 | 0.5358 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0219 | 0.0121 | 0.0909 | 0.0388 | 0.1285 | 0.1068 | 0.1003 | 0.0485 | 0.1317 | 0.0801 | 0.5235 | 0.7136 | 0.0127 | 0.0000 | 0.0506 | 0.0571 | 0.0253 | 0.0286 | 0.1266 | 0.3143 | 0.2025 | 0.1429 | 0.1772 | 0.2571 | 0.1392 | 0.2000 | 0.1266 | 0.0000 | 0.1392 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0914 | 0.1452 | 0.1935 | 0.1774 | 0.1452 | 0.2366 | 25 | 49 | 96 | 153 | 212 | 275 | 354 | 477 | 655 | 0.0063 | 78.62 | 6.665 | 0.3190 | 142608.0 | 95700000 | 75600000000 | 66600000000000 | 0.5065 | 0.1700 | 0.0221 | 0.0019 | 0.0858 | 0.0044 | 0.1495 | 0.0386 | 0.1507 | 0.0880 | 0.1667 | 0.1381 | 0.1507 | 0.1837 | 0.1164 | 0.1343 | 0.0931 | 0.1279 | 0.0650 | 0.2831 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0045 | 0.0010 | 0.0179 | 0.0102 | 0.0595 | 0.0459 | 0.0965 | 0.0856 | 0.0892 | 0.0652 | 0.1071 | 0.0883 | 0.6244 | 0.7037 | 0.0018 | 0.0007 | 0.0031 | 0.0044 | 0.0067 | 0.0095 | 0.0329 | 0.0352 | 0.0940 | 0.1232 | 0.1416 | 0.1576 | 0.1159 | 0.1188 | 0.1495 | 0.1503 | 0.4545 | 0.4003 | 0.0010 | 0.0015 | 0.0050 | 0.0223 | 0.0819 | 0.1166 | 0.1052 | 0.1454 | 0.5211 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 820 | 689 | | 340 | 1923 | 397.1 | 79.43 | 199.34 | 201.26 | 294 | 333 | 352 | 372 | 390 | 408 | 435 | 465 | 504 | 0.1394 | 268 | 1.182 | 145.07 | 47.10 | 3 | 1.0029 | 341 | 0.0036 | 115.51 | 5.687 | 0.1125 | 163958.0 | 70300000 | 31200000000 | 14300000000000 | 0.3965 | 0.2306 | 0.0000 | 0.0000 | 0.0174 | 0.0000 | 0.0217 | 0.0000 | 0.0957 | 0.0245 | 0.1478 | 0.0890 | 0.1913 | 0.1196 | 0.1783 | 0.0706 | 0.1043 | 0.1135 | 0.2435 | 0.5828 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0241 | 0.0118 | 0.1069 | 0.0737 | 0.1621 | 0.1121 | 0.1241 | 0.0619 | 0.1241 | 0.1003 | 0.4517 | 0.6401 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0500 | 0.2308 | 0.1333 | 0.0000 | 0.2000 | 0.3077 | 0.2167 | 0.1538 | 0.0833 | 0.1538 | 0.1500 | 0.1538 | 0.1667 | 0.0000 | 0.0000 | 0.0000 | 0.0189 | 0.0818 | 0.1635 | 0.2075 | 0.1258 | 0.1635 | 0.2390 | 20 | 36 | 64 | 93 | 120 | 173 | 254 | 366 | 476 | 0.0098 | 59.99 | 5.843 | 0.3632 | 80219.5 | 45700000 | 32800000000 | 28000000000000 | 0.5269 | 0.1237 | 0.0813 | 0.0000 | 0.2536 | 0.0321 | 0.3971 | 0.1514 | 0.1579 | 0.2041 | 0.0478 | 0.2110 | 0.0287 | 0.2064 | 0.0144 | 0.0940 | 0.0191 | 0.0550 | 0.0000 | 0.0459 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0012 | 0.0042 | 0.0135 | 0.0156 | 0.0800 | 0.0582 | 0.1441 | 0.1163 | 0.0985 | 0.0789 | 0.1195 | 0.1184 | 0.5431 | 0.6075 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0057 | 0.0332 | 0.0361 | 0.1144 | 0.1347 | 0.1841 | 0.1822 | 0.1061 | 0.1101 | 0.1426 | 0.1480 | 0.4179 | 0.3833 | 0.0000 | 0.0000 | 0.0000 | 0.0142 | 0.1095 | 0.1551 | 0.1053 | 0.1351 | 0.4808 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 309 | 735 | | 1819 | 14901 | 73.2 | 15.19 | 136.21 | 157.45 | 56 | 62 | 65 | 67 | 70 | 74 | 79 | 85 | 94 | 0.0571 | 851 | 0.961 | 66.85 | 20.22 | 3 | 0.0995 | 181 | 0.0042 | 13.83 | 5.799 | 0.2858 | 5584.7 | 444991 | 37000000 | 3220000000 | 0.5015 | 0.1554 | 0.0008 | 0.0000 | 0.0047 | 0.0006 | 0.0228 | 0.0012 | 0.0417 | 0.0140 | 0.1133 | 0.0450 | 0.1707 | 0.1040 | 0.1526 | 0.0900 | 0.1794 | 0.1244 | 0.3139 | 0.6209 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0069 | 0.0011 | 0.0202 | 0.0117 | 0.0656 | 0.0362 | 0.1040 | 0.0841 | 0.0807 | 0.0523 | 0.1230 | 0.0885 | 0.5984 | 0.7255 | 0.0095 | 0.0238 | 0.0063 | 0.0357 | 0.0381 | 0.1190 | 0.1175 | 0.2381 | 0.1460 | 0.1905 | 0.2190 | 0.1429 | 0.1238 | 0.0833 | 0.1143 | 0.0833 | 0.2254 | 0.0833 | 0.0025 | 0.0135 | 0.0197 | 0.0492 | 0.1095 | 0.1365 | 0.1267 | 0.1501 | 0.3924 | 14 | 17 | 23 | 40 | 73 | 110 | 160 | 243 | 367 | 0.0319 | 18.03 | 5.311 | 0.4923 | 43340.4 | 19300000 | 10300000000 | 6180000000000 | 0.4512 | 0.1992 | 0.0348 | 0.0006 | 0.1211 | 0.0135 | 0.2124 | 0.0737 | 0.1696 | 0.0995 | 0.1621 | 0.1575 | 0.1286 | 0.1894 | 0.0776 | 0.1317 | 0.0547 | 0.1357 | 0.0391 | 0.1983 | 0.0008 | 0.0000 | 0.0012 | 0.0006 | 0.0050 | 0.0021 | 0.0163 | 0.0107 | 0.0553 | 0.0478 | 0.0947 | 0.0811 | 0.0696 | 0.0552 | 0.0962 | 0.0929 | 0.6610 | 0.7096 | 0.0009 | 0.0008 | 0.0018 | 0.0024 | 0.0075 | 0.0050 | 0.0218 | 0.0214 | 0.0693 | 0.0833 | 0.1160 | 0.1303 | 0.0869 | 0.0844 | 0.1141 | 0.1295 | 0.5816 | 0.5430 | 0.0008 | 0.0010 | 0.0031 | 0.0189 | 0.0617 | 0.1060 | 0.0742 | 0.1094 | 0.6249 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1173 | 230 | | 893 | 1587 | 58.0 | 13.43 | 491.67 | 350.26 | 39 | 45 | 50 | 54 | 59 | 63 | 67 | 71 | 75 | 0.1878 | 298 | 1.216 | 22.85 | 8.25 | 1 | 0.0694 | 62 | 0.0063 | 5.77 | 5.275 | 0.3973 | 3548.7 | 226676 | 15000000 | 1020000000 | 0.4245 | 0.2042 | 0.0041 | 0.0000 | 0.0104 | 0.0000 | 0.0228 | 0.0012 | 0.0352 | 0.0119 | 0.1056 | 0.0380 | 0.1201 | 0.0403 | 0.1677 | 0.0712 | 0.1822 | 0.0830 | 0.3520 | 0.7544 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0058 | 0.0012 | 0.0159 | 0.0116 | 0.0418 | 0.0359 | 0.0390 | 0.0348 | 0.0592 | 0.0475 | 0.0649 | 0.0487 | 0.7706 | 0.8204 | 0.0095 | 0.0500 | 0.0143 | 0.1000 | 0.0190 | 0.0500 | 0.0476 | 0.2000 | 0.1381 | 0.3000 | 0.1095 | 0.1000 | 0.1810 | 0.0000 | 0.1905 | 0.2000 | 0.2905 | 0.0000 | 0.0043 | 0.0151 | 0.0151 | 0.0129 | 0.0430 | 0.0688 | 0.0860 | 0.1011 | 0.6538 | 107 | 162 | 233 | 315 | 418 | 517 | 636 | 803 | 998 | 0.0021 | 39.34 | 6.548 | 0.2363 | 364349.0 | 335000000 | 350000000000 | 398000000000000 | 0.5161 | 0.1411 | 0.0070 | 0.0000 | 0.0702 | 0.0035 | 0.1579 | 0.0228 | 0.2316 | 0.0683 | 0.2140 | 0.1278 | 0.1789 | 0.2277 | 0.0877 | 0.1611 | 0.0386 | 0.1664 | 0.0140 | 0.2224 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0061 | 0.0020 | 0.0255 | 0.0201 | 0.0522 | 0.0413 | 0.0765 | 0.0554 | 0.0667 | 0.0564 | 0.1129 | 0.0816 | 0.6590 | 0.7432 | 0.0019 | 0.0000 | 0.0000 | 0.0047 | 0.0111 | 0.0213 | 0.0390 | 0.0332 | 0.0686 | 0.0900 | 0.1317 | 0.1232 | 0.0891 | 0.0853 | 0.1132 | 0.1422 | 0.5455 | 0.5000 | 0.0000 | 0.0059 | 0.0089 | 0.0341 | 0.0548 | 0.0904 | 0.0919 | 0.1407 | 0.5733 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 337 | 336 | | 436 | 1226 | 74.6 | 15.23 | 8.13 | 2.56 | 60 | 63 | 66 | 68 | 70 | 73 | 77 | 87 | 99 | 0.2047 | 251 | 1.186 | 32.02 | 11.05 | 1 | 0.1904 | 83 | 0.0637 | 1.09 | 3.210 | 0.6546 | 5802.3 | 471400 | 40100000 | 3560000000 | 0.4209 | 0.2111 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0159 | 0.0074 | 0.0349 | 0.0123 | 0.1111 | 0.0539 | 0.1714 | 0.1176 | 0.1270 | 0.1176 | 0.1302 | 0.1544 | 0.4095 | 0.5368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0069 | 0.0280 | 0.0115 | 0.0509 | 0.0413 | 0.0865 | 0.0894 | 0.0789 | 0.0642 | 0.0941 | 0.0917 | 0.6539 | 0.6950 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0128 | 0.1429 | 0.0641 | 0.2500 | 0.0897 | 0.2143 | 0.2821 | 0.1786 | 0.1282 | 0.1071 | 0.1154 | 0.0714 | 0.3077 | 0.0357 | 0.0134 | 0.0067 | 0.0000 | 0.0537 | 0.0872 | 0.1409 | 0.0940 | 0.1208 | 0.4832 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0165 | 10.44 | 4.481 | 0.3254 | 72.6 | 704.432 | 7374.94 | 83019.4 | 0.4958 | 0.1499 | 0.0199 | 0.0010 | 0.0634 | 0.0049 | 0.1793 | 0.0119 | 0.2500 | 0.0415 | 0.2591 | 0.0889 | 0.1612 | 0.1235 | 0.0562 | 0.2075 | 0.0091 | 0.3063 | 0.0018 | 0.2144 | 0.0011 | 0.0000 | 0.0103 | 0.0018 | 0.0411 | 0.0044 | 0.0959 | 0.0176 | 0.1610 | 0.0668 | 0.1826 | 0.0809 | 0.1724 | 0.1161 | 0.2226 | 0.2577 | 0.1130 | 0.4547 | 0.1204 | 0.2880 | 0.1821 | 0.2640 | 0.2006 | 0.1600 | 0.1728 | 0.1280 | 0.1512 | 0.0880 | 0.0895 | 0.0560 | 0.0525 | 0.0160 | 0.0278 | 0.0000 | 0.0031 | 0.0000 | 0.0118 | 0.0485 | 0.1132 | 0.1559 | 0.1529 | 0.1500 | 0.1853 | 0.1250 | 0.0574 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1251 | 214 | | 356 | 5823 | 35.2 | 7.41 | 113.18 | 175.08 | 27 | 29 | 30 | 32 | 34 | 37 | 39 | 42 | 46 | 0.0792 | 461 | 0.420 | 101.19 | 15.26 | 1 | 0.8736 | 311 | 0.0113 | 6.98 | 4.700 | 0.3318 | 1292.1 | 49511.8 | 1970000 | 81800000 | 0.4112 | 0.2070 | 0.0000 | 0.0000 | 0.0044 | 0.0000 | 0.0439 | 0.0000 | 0.0877 | 0.0118 | 0.1711 | 0.0708 | 0.1798 | 0.0678 | 0.2719 | 0.1121 | 0.1491 | 0.1563 | 0.0921 | 0.5811 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0000 | 0.0261 | 0.0113 | 0.0554 | 0.0592 | 0.0782 | 0.0563 | 0.1401 | 0.0676 | 0.1759 | 0.0901 | 0.5049 | 0.7155 | 0.0127 | 0.0625 | 0.0000 | 0.1250 | 0.0759 | 0.0625 | 0.2532 | 0.2500 | 0.1646 | 0.1250 | 0.1772 | 0.1875 | 0.1139 | 0.1250 | 0.1013 | 0.0625 | 0.1013 | 0.0000 | 0.0000 | 0.0242 | 0.0424 | 0.0667 | 0.1030 | 0.1576 | 0.1455 | 0.1636 | 0.2970 | 16 | 20 | 25 | 33 | 45 | 68 | 103 | 161 | 264 | 0.0724 | 6.00 | 4.044 | 0.6522 | 43457.4 | 30200000 | 26300000000 | 25200000000000 | 0.6089 | 0.0954 | 0.0138 | 0.0044 | 0.0881 | 0.0044 | 0.1796 | 0.0413 | 0.1503 | 0.0739 | 0.1658 | 0.1706 | 0.1330 | 0.1715 | 0.1278 | 0.1407 | 0.0950 | 0.1416 | 0.0466 | 0.2515 | 0.0000 | 0.0009 | 0.0015 | 0.0004 | 0.0041 | 0.0017 | 0.0164 | 0.0133 | 0.0590 | 0.0506 | 0.0878 | 0.0665 | 0.0678 | 0.0545 | 0.0965 | 0.0982 | 0.6668 | 0.7139 | 0.0015 | 0.0000 | 0.0015 | 0.0017 | 0.0037 | 0.0050 | 0.0161 | 0.0209 | 0.0701 | 0.0771 | 0.1103 | 0.1131 | 0.0621 | 0.0737 | 0.1169 | 0.1307 | 0.6180 | 0.5779 | 0.0006 | 0.0031 | 0.0043 | 0.0210 | 0.0611 | 0.0945 | 0.0667 | 0.1050 | 0.6436 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 854 | 856 | | 7221 | 14570 | 49.4 | 17.53 | 78.00 | 136.28 | 28 | 34 | 38 | 43 | 47 | 52 | 58 | 64 | 73 | 0.0925 | 1347 | 0.564 | 226.82 | 39.32 | 13 | 0.0867 | 626 | 0.0060 | 6.82 | 5.419 | 0.3768 | 2746.4 | 169000 | 11300000 | 819000000 | 0.4385 | 0.1979 | 0.0021 | 0.0002 | 0.0092 | 0.0013 | 0.0509 | 0.0036 | 0.1206 | 0.0209 | 0.1835 | 0.0519 | 0.1998 | 0.1171 | 0.1729 | 0.1192 | 0.1266 | 0.1517 | 0.1344 | 0.5342 | 0.0004 | 0.0000 | 0.0012 | 0.0005 | 0.0037 | 0.0013 | 0.0217 | 0.0112 | 0.0562 | 0.0266 | 0.0864 | 0.0540 | 0.0848 | 0.0579 | 0.1085 | 0.0691 | 0.6371 | 0.7796 | 0.0039 | 0.0097 | 0.0073 | 0.0154 | 0.0194 | 0.0328 | 0.0682 | 0.0936 | 0.1094 | 0.1380 | 0.1510 | 0.1979 | 0.1292 | 0.1342 | 0.1549 | 0.1467 | 0.3567 | 0.2317 | 0.0017 | 0.0026 | 0.0125 | 0.0408 | 0.0755 | 0.1098 | 0.1078 | 0.1329 | 0.5163 | 11 | 13 | 15 | 17 | 20 | 26 | 46 | 104 | 234 | 0.1860 | 10.58 | 3.510 | 0.6862 | 24655.2 | 13200000 | 8940000000 | 7000000000000 | 0.6410 | 0.1101 | 0.1548 | 0.0039 | 0.3289 | 0.0394 | 0.2946 | 0.2229 | 0.1131 | 0.2327 | 0.0565 | 0.2189 | 0.0298 | 0.1433 | 0.0134 | 0.0671 | 0.0074 | 0.0493 | 0.0015 | 0.0224 | 0.0008 | 0.0002 | 0.0008 | 0.0005 | 0.0032 | 0.0053 | 0.0201 | 0.0138 | 0.0823 | 0.0766 | 0.1173 | 0.0994 | 0.0839 | 0.0713 | 0.1284 | 0.1266 | 0.5631 | 0.6063 | 0.0003 | 0.0007 | 0.0023 | 0.0021 | 0.0058 | 0.0053 | 0.0229 | 0.0248 | 0.1011 | 0.1076 | 0.1308 | 0.1522 | 0.0995 | 0.0995 | 0.1485 | 0.1501 | 0.4889 | 0.4577 | 0.0000 | 0.0023 | 0.0053 | 0.0197 | 0.0978 | 0.1169 | 0.0934 | 0.1436 | 0.5211 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 129 | 102 | | 853 | 4631 | 107.8 | 32.30 | 12.53 | 4.15 | 72 | 80 | 87 | 94 | 102 | 110 | 119 | 135 | 159 | 0.1162 | 538 | 1.081 | 46.87 | 17.49 | 1 | 0.1489 | 127 | 0.0142 | 2.79 | 4.517 | 0.4969 | 12655.4 | 1610000 | 221000000 | 32300000000 | 0.4358 | 0.2021 | 0.0024 | 0.0000 | 0.0024 | 0.0028 | 0.0097 | 0.0014 | 0.0607 | 0.0185 | 0.1602 | 0.0541 | 0.1990 | 0.1223 | 0.1553 | 0.0896 | 0.1456 | 0.1181 | 0.2646 | 0.5932 | 0.0017 | 0.0000 | 0.0017 | 0.0012 | 0.0066 | 0.0000 | 0.0249 | 0.0111 | 0.0731 | 0.0382 | 0.0897 | 0.0764 | 0.0797 | 0.0480 | 0.1030 | 0.0640 | 0.6196 | 0.7611 | 0.0000 | 0.0000 | 0.0105 | 0.0000 | 0.0105 | 0.0092 | 0.0316 | 0.0734 | 0.0947 | 0.1376 | 0.1211 | 0.1835 | 0.0789 | 0.1193 | 0.1421 | 0.1835 | 0.5105 | 0.2936 | 0.0055 | 0.0055 | 0.0110 | 0.0440 | 0.0769 | 0.1044 | 0.1181 | 0.1209 | 0.5137 | 7 | 9 | 10 | 11 | 12 | 13 | 14 | 16 | 18 | 0.0078 | 26.38 | 5.307 | 0.2385 | 174.1 | 2649.31 | 43748.6 | 779909 | 0.5184 | 0.1395 | 0.0240 | 0.0003 | 0.0831 | 0.0035 | 0.1717 | 0.0122 | 0.2432 | 0.0319 | 0.2538 | 0.0856 | 0.1461 | 0.1297 | 0.0621 | 0.2158 | 0.0130 | 0.3053 | 0.0030 | 0.2158 | 0.0040 | 0.0000 | 0.0242 | 0.0010 | 0.0646 | 0.0043 | 0.1036 | 0.0183 | 0.1480 | 0.0550 | 0.1705 | 0.0815 | 0.1609 | 0.1399 | 0.1487 | 0.2628 | 0.1755 | 0.4372 | 0.1595 | 0.2552 | 0.1673 | 0.1849 | 0.1399 | 0.1094 | 0.1145 | 0.1484 | 0.1243 | 0.1198 | 0.0920 | 0.0964 | 0.0841 | 0.0495 | 0.0626 | 0.0339 | 0.0558 | 0.0026 | 0.0301 | 0.0872 | 0.1248 | 0.1442 | 0.1442 | 0.1368 | 0.1113 | 0.1076 | 0.1136 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 84 | 350 | | 635 | 11961 | 63.2 | 10.04 | 161.70 | 197.63 | 50 | 54 | 57 | 61 | 63 | 66 | 68 | 71 | 76 | 0.0579 | 693 | 0.875 | 142.76 | 45.97 | 2 | 0.6299 | 400 | 0.0068 | 11.22 | 5.192 | 0.3174 | 4092.7 | 271580 | 18400000 | 1280000000 | 0.4246 | 0.2192 | 0.0020 | 0.0000 | 0.0061 | 0.0016 | 0.0242 | 0.0048 | 0.0364 | 0.0111 | 0.0667 | 0.0430 | 0.1091 | 0.0685 | 0.1172 | 0.0525 | 0.1960 | 0.0812 | 0.4424 | 0.7373 | 0.0018 | 0.0000 | 0.0053 | 0.0016 | 0.0124 | 0.0047 | 0.0284 | 0.0110 | 0.0443 | 0.0379 | 0.0585 | 0.0694 | 0.0709 | 0.0394 | 0.0816 | 0.0599 | 0.6968 | 0.7760 | 0.0580 | 0.3333 | 0.0870 | 0.0000 | 0.1594 | 0.3333 | 0.0725 | 0.3333 | 0.1739 | 0.0000 | 0.0870 | 0.0000 | 0.0580 | 0.0000 | 0.1014 | 0.0000 | 0.2029 | 0.0000 | 0.0060 | 0.0030 | 0.0328 | 0.0448 | 0.0836 | 0.1045 | 0.1104 | 0.1761 | 0.4388 | 14 | 18 | 22 | 31 | 58 | 116 | 205 | 315 | 458 | 0.0352 | 28.43 | 5.403 | 0.4619 | 65200.6 | 35400000 | 22500000000 | 16100000000000 | 0.5927 | 0.1032 | 0.1018 | 0.0034 | 0.2284 | 0.0353 | 0.3243 | 0.1826 | 0.1467 | 0.1894 | 0.1089 | 0.2031 | 0.0462 | 0.1570 | 0.0249 | 0.0990 | 0.0130 | 0.0728 | 0.0059 | 0.0575 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0020 | 0.0022 | 0.0142 | 0.0124 | 0.0583 | 0.0519 | 0.0965 | 0.0944 | 0.0720 | 0.0609 | 0.0991 | 0.0924 | 0.6569 | 0.6855 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0029 | 0.0060 | 0.0195 | 0.0279 | 0.0776 | 0.0835 | 0.1193 | 0.1370 | 0.0921 | 0.0943 | 0.1271 | 0.1346 | 0.5598 | 0.5161 | 0.0002 | 0.0002 | 0.0027 | 0.0176 | 0.0677 | 0.1015 | 0.0832 | 0.1135 | 0.6134 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 56 | 911 | | 384 | 7332 | 60.6 | 12.76 | 165.06 | 118.18 | 45 | 50 | 53 | 57 | 60 | 63 | 67 | 71 | 76 | 0.0614 | 450 | 0.519 | 130.54 | 26.91 | 0 | 1.0260 | 394 | 0.0099 | 9.19 | 4.826 | 0.3167 | 3828.9 | 252540 | 17400000 | 1250000000 | 0.4554 | 0.1729 | 0.0036 | 0.0000 | 0.0109 | 0.0028 | 0.0182 | 0.0055 | 0.0691 | 0.0194 | 0.1309 | 0.0720 | 0.1709 | 0.1219 | 0.1782 | 0.0914 | 0.2000 | 0.1607 | 0.2182 | 0.5263 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0093 | 0.0027 | 0.0247 | 0.0107 | 0.0957 | 0.0587 | 0.1235 | 0.1147 | 0.1173 | 0.0667 | 0.1420 | 0.1333 | 0.4877 | 0.6107 | 0.1020 | 0.0000 | 0.0612 | 0.1429 | 0.1224 | 0.0714 | 0.1020 | 0.3571 | 0.1633 | 0.2857 | 0.1837 | 0.0714 | 0.1633 | 0.0714 | 0.0612 | 0.0000 | 0.0408 | 0.0000 | 0.0053 | 0.0000 | 0.0106 | 0.0638 | 0.1596 | 0.1702 | 0.1596 | 0.1915 | 0.2394 | 18 | 37 | 71 | 117 | 158 | 195 | 232 | 274 | 329 | 0.0075 | 22.50 | 6.081 | 0.3343 | 41207.1 | 12200000 | 3970000000 | 1400000000000 | 0.4642 | 0.1955 | 0.0148 | 0.0016 | 0.1134 | 0.0089 | 0.1997 | 0.0335 | 0.1935 | 0.0895 | 0.1671 | 0.1734 | 0.1507 | 0.1952 | 0.0870 | 0.1593 | 0.0583 | 0.1613 | 0.0155 | 0.1774 | 0.0000 | 0.0000 | 0.0005 | 0.0013 | 0.0024 | 0.0011 | 0.0128 | 0.0077 | 0.0443 | 0.0302 | 0.0775 | 0.0562 | 0.0828 | 0.0523 | 0.1239 | 0.0826 | 0.6558 | 0.7687 | 0.0003 | 0.0023 | 0.0052 | 0.0099 | 0.0108 | 0.0185 | 0.0241 | 0.0468 | 0.0927 | 0.1342 | 0.1524 | 0.1640 | 0.1405 | 0.1486 | 0.1552 | 0.1721 | 0.4188 | 0.3036 | 0.0011 | 0.0025 | 0.0040 | 0.0178 | 0.0627 | 0.1136 | 0.1110 | 0.1627 | 0.5246 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 372 | 139 | | 4417 | 11190 | 35.9 | 14.42 | 6.81 | 2.68 | 18 | 23 | 27 | 31 | 35 | 38 | 42 | 47 | 55 | 0.1108 | 1240 | 0.972 | 96.52 | 27.73 | 0 | 0.0541 | 239 | 0.0016 | 19.80 | 6.657 | 0.2399 | 1496.0 | 70708.7 | 3720000 | 215000000 | 0.3566 | 0.2612 | 0.0074 | 0.0033 | 0.0138 | 0.0046 | 0.0275 | 0.0100 | 0.0401 | 0.0219 | 0.0682 | 0.0306 | 0.1181 | 0.0604 | 0.1456 | 0.0764 | 0.2189 | 0.1249 | 0.3605 | 0.6679 | 0.0027 | 0.0016 | 0.0044 | 0.0025 | 0.0061 | 0.0041 | 0.0123 | 0.0106 | 0.0194 | 0.0144 | 0.0310 | 0.0289 | 0.0358 | 0.0324 | 0.0607 | 0.0501 | 0.8275 | 0.8554 | 0.0135 | 0.0136 | 0.0143 | 0.0303 | 0.0236 | 0.0394 | 0.0412 | 0.0455 | 0.0648 | 0.0636 | 0.0732 | 0.0924 | 0.0875 | 0.1030 | 0.1052 | 0.1288 | 0.5766 | 0.4833 | 0.0024 | 0.0118 | 0.0142 | 0.0217 | 0.0307 | 0.0558 | 0.0728 | 0.1281 | 0.6626 | 3 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0130 | 14.88 | 4.690 | 0.2835 | 53.5 | 466.389 | 4418.91 | 44994.1 | 0.5386 | 0.1220 | 0.0193 | 0.0018 | 0.0771 | 0.0147 | 0.1782 | 0.0531 | 0.2352 | 0.1151 | 0.2415 | 0.1932 | 0.1553 | 0.2539 | 0.0676 | 0.2164 | 0.0219 | 0.1202 | 0.0039 | 0.0316 | 0.0009 | 0.0001 | 0.0099 | 0.0021 | 0.0376 | 0.0123 | 0.0944 | 0.0380 | 0.1707 | 0.0873 | 0.2304 | 0.1689 | 0.2167 | 0.2533 | 0.1681 | 0.2793 | 0.0711 | 0.1586 | 0.1499 | 0.2801 | 0.2687 | 0.3198 | 0.2320 | 0.2121 | 0.1617 | 0.1088 | 0.0909 | 0.0480 | 0.0568 | 0.0201 | 0.0279 | 0.0084 | 0.0099 | 0.0022 | 0.0022 | 0.0006 | 0.0072 | 0.0437 | 0.1150 | 0.1799 | 0.2208 | 0.1990 | 0.1331 | 0.0731 | 0.0283 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 469 | 438 | | 2983 | 6904 | 291.5 | 155.73 | 25.80 | 36.51 | 163 | 179 | 192 | 210 | 232 | 259 | 292 | 423 | 579 | 0.1047 | 723 | 0.563 | 78.24 | 21.26 | 5 | 0.0865 | 258 | 0.0031 | 12.41 | 6.310 | 0.3653 | 109220.0 | 50500000 | 26800000000 | 15300000000000 | 0.4115 | 0.2245 | 0.0013 | 0.0000 | 0.0013 | 0.0011 | 0.0053 | 0.0049 | 0.0279 | 0.0152 | 0.0810 | 0.0455 | 0.1514 | 0.0829 | 0.1142 | 0.0650 | 0.1116 | 0.0861 | 0.5060 | 0.6994 | 0.0007 | 0.0000 | 0.0007 | 0.0008 | 0.0027 | 0.0036 | 0.0129 | 0.0101 | 0.0278 | 0.0283 | 0.0394 | 0.0449 | 0.0455 | 0.0377 | 0.0502 | 0.0494 | 0.8201 | 0.8251 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0048 | 0.0250 | 0.0353 | 0.0722 | 0.0609 | 0.0222 | 0.0304 | 0.0431 | 0.0529 | 0.8333 | 0.8157 | 0.0000 | 0.0022 | 0.0078 | 0.0100 | 0.0288 | 0.0654 | 0.0310 | 0.0488 | 0.8060 | 7 | 9 | 10 | 12 | 14 | 17 | 22 | 30 | 49 | 0.1051 | 1.66 | 3.110 | 0.7374 | 1998.1 | 320182 | 69200000 | 17600000000 | 0.5249 | 0.1326 | 0.0229 | 0.0158 | 0.0439 | 0.0273 | 0.0768 | 0.0379 | 0.1286 | 0.0532 | 0.1655 | 0.0873 | 0.1864 | 0.1237 | 0.1685 | 0.1324 | 0.1256 | 0.1938 | 0.0818 | 0.3285 | 0.0053 | 0.0100 | 0.0107 | 0.0158 | 0.0191 | 0.0197 | 0.0364 | 0.0262 | 0.0631 | 0.0494 | 0.1039 | 0.0862 | 0.0795 | 0.0733 | 0.0955 | 0.1172 | 0.5866 | 0.6021 | 0.0056 | 0.0129 | 0.0104 | 0.0069 | 0.0288 | 0.0247 | 0.0400 | 0.0366 | 0.0737 | 0.0791 | 0.1017 | 0.1098 | 0.0745 | 0.0692 | 0.1129 | 0.0930 | 0.5524 | 0.5678 | 0.0070 | 0.0152 | 0.0275 | 0.0427 | 0.0719 | 0.1029 | 0.0830 | 0.0918 | 0.5582 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 684 | 361 | | 399 | 6206 | 58.4 | 9.74 | 24.73 | 66.86 | 46 | 49 | 52 | 54 | 57 | 61 | 64 | 69 | 72 | 0.1017 | 631 | 0.682 | 36.24 | 8.54 | 1 | 0.2607 | 104 | 0.0248 | 2.23 | 3.908 | 0.5277 | 3503.6 | 215851 | 13600000 | 881000000 | 0.3536 | 0.2676 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0071 | 0.0000 | 0.0426 | 0.0101 | 0.0922 | 0.0628 | 0.1525 | 0.0678 | 0.1489 | 0.0653 | 0.1915 | 0.0879 | 0.3617 | 0.7060 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0225 | 0.0100 | 0.0535 | 0.0627 | 0.0817 | 0.0677 | 0.0789 | 0.0652 | 0.1042 | 0.0677 | 0.6563 | 0.7268 | 0.0137 | 1.0000 | 0.0000 | 0.0000 | 0.0274 | 0.0000 | 0.0822 | 0.0000 | 0.0822 | 0.0000 | 0.1781 | 0.0000 | 0.1370 | 0.0000 | 0.2055 | 0.0000 | 0.2740 | 0.0000 | 0.0053 | 0.0053 | 0.0159 | 0.0265 | 0.0635 | 0.1111 | 0.1058 | 0.0899 | 0.5767 | 5 | 6 | 7 | 8 | 9 | 10 | 13 | 18 | 40 | 0.3348 | 9.79 | 2.064 | 0.7707 | 5081.6 | 2730000 | 1940000000 | 1570000000000 | 0.6341 | 0.0846 | 0.0349 | 0.0330 | 0.1163 | 0.0366 | 0.1453 | 0.0425 | 0.1628 | 0.0837 | 0.2006 | 0.1262 | 0.1919 | 0.1498 | 0.1163 | 0.1462 | 0.0233 | 0.1686 | 0.0087 | 0.2134 | 0.0053 | 0.0181 | 0.0079 | 0.0194 | 0.0184 | 0.0148 | 0.0202 | 0.0258 | 0.0746 | 0.0523 | 0.0886 | 0.0690 | 0.0912 | 0.0800 | 0.1202 | 0.1052 | 0.5737 | 0.6155 | 0.0025 | 0.0028 | 0.0013 | 0.0000 | 0.0088 | 0.0043 | 0.0251 | 0.0256 | 0.0842 | 0.0954 | 0.1256 | 0.1439 | 0.0942 | 0.1068 | 0.1344 | 0.1296 | 0.5239 | 0.4915 | 0.0022 | 0.0098 | 0.0065 | 0.0271 | 0.0869 | 0.0912 | 0.0988 | 0.1325 | 0.5451 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1243 | 854 | | 722 | 7966 | 63.7 | 17.26 | 99.18 | 192.37 | 47 | 51 | 53 | 56 | 60 | 63 | 68 | 74 | 85 | 0.0734 | 585 | 0.421 | 183.11 | 37.80 | 0 | 0.8726 | 630 | 0.0093 | 10.56 | 5.018 | 0.3434 | 4360.7 | 324711 | 26600000 | 2420000000 | 0.4665 | 0.1732 | 0.0048 | 0.0000 | 0.0238 | 0.0000 | 0.0499 | 0.0060 | 0.0950 | 0.0255 | 0.1354 | 0.0510 | 0.1853 | 0.0990 | 0.1663 | 0.1049 | 0.1663 | 0.1094 | 0.1734 | 0.6042 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0128 | 0.0028 | 0.0475 | 0.0097 | 0.0786 | 0.0444 | 0.1408 | 0.0819 | 0.1261 | 0.0611 | 0.1481 | 0.0833 | 0.4388 | 0.7167 | 0.0000 | 0.0000 | 0.0317 | 0.0377 | 0.0159 | 0.0755 | 0.0952 | 0.0755 | 0.1825 | 0.3019 | 0.1825 | 0.1321 | 0.1508 | 0.0566 | 0.1508 | 0.2075 | 0.1905 | 0.1132 | 0.0036 | 0.0180 | 0.0288 | 0.0791 | 0.1259 | 0.1691 | 0.1295 | 0.1511 | 0.2950 | 10 | 12 | 14 | 15 | 17 | 19 | 31 | 113 | 371 | 0.1151 | 73.14 | 4.084 | 0.5429 | 46837.2 | 32700000 | 27500000000 | 26300000000000 | 0.6007 | 0.1115 | 0.2664 | 0.0211 | 0.4953 | 0.1607 | 0.2103 | 0.5011 | 0.0280 | 0.1882 | 0.0000 | 0.0782 | 0.0000 | 0.0338 | 0.0000 | 0.0127 | 0.0000 | 0.0042 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0022 | 0.0015 | 0.0056 | 0.0036 | 0.0185 | 0.0247 | 0.0888 | 0.0781 | 0.1355 | 0.1183 | 0.0748 | 0.0848 | 0.1231 | 0.1177 | 0.5509 | 0.5707 | 0.0006 | 0.0007 | 0.0013 | 0.0041 | 0.0083 | 0.0082 | 0.0230 | 0.0211 | 0.0856 | 0.0958 | 0.1540 | 0.1501 | 0.0818 | 0.0795 | 0.1176 | 0.1291 | 0.5278 | 0.5115 | 0.0012 | 0.0024 | 0.0054 | 0.0198 | 0.0929 | 0.1360 | 0.0827 | 0.1210 | 0.5386 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 328 | 685 | | 3310 | 17319 | 115.5 | 44.52 | 5.43 | 1.99 | 62 | 70 | 80 | 93 | 109 | 124 | 140 | 161 | 181 | 0.0577 | 999 | 0.991 | 31.40 | 10.77 | 2 | 0.0266 | 88 | 0.0050 | 4.21 | 5.619 | 0.4414 | 15310.3 | 2260000 | 362000000 | 61100000000 | 0.3498 | 0.2779 | 0.0021 | 0.0010 | 0.0072 | 0.0039 | 0.0123 | 0.0093 | 0.0349 | 0.0181 | 0.0739 | 0.0366 | 0.1242 | 0.0439 | 0.1232 | 0.0649 | 0.1828 | 0.0825 | 0.4394 | 0.7399 | 0.0005 | 0.0007 | 0.0015 | 0.0026 | 0.0035 | 0.0048 | 0.0089 | 0.0096 | 0.0212 | 0.0177 | 0.0227 | 0.0184 | 0.0257 | 0.0302 | 0.0420 | 0.0350 | 0.8741 | 0.8809 | 0.0010 | 0.0000 | 0.0019 | 0.0045 | 0.0086 | 0.0106 | 0.0209 | 0.0151 | 0.0409 | 0.0452 | 0.0571 | 0.0603 | 0.0523 | 0.0724 | 0.0647 | 0.0799 | 0.7526 | 0.7119 | 0.0013 | 0.0000 | 0.0013 | 0.0097 | 0.0232 | 0.0387 | 0.0290 | 0.0574 | 0.8395 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.2714 | 0.47 | 1.049 | 0.6358 | 33.5 | 227.156 | 1669.44 | 13153.9 | 0.4485 | 0.2089 | 0.0313 | 0.0023 | 0.0940 | 0.0125 | 0.1602 | 0.0406 | 0.2077 | 0.0829 | 0.2080 | 0.1416 | 0.1737 | 0.2164 | 0.0888 | 0.2463 | 0.0321 | 0.1826 | 0.0043 | 0.0747 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0030 | 0.0008 | 0.0099 | 0.0050 | 0.0301 | 0.0153 | 0.0780 | 0.0258 | 0.2017 | 0.0630 | 0.3485 | 0.2345 | 0.3287 | 0.6554 | 0.0177 | 0.0768 | 0.0775 | 0.1643 | 0.1302 | 0.2136 | 0.1742 | 0.2130 | 0.1942 | 0.1573 | 0.1860 | 0.0951 | 0.1327 | 0.0548 | 0.0683 | 0.0195 | 0.0192 | 0.0057 | 0.0007 | 0.0109 | 0.0459 | 0.1123 | 0.1876 | 0.2387 | 0.2118 | 0.1393 | 0.0528 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1200 | 960 | | 312 | 3292 | 82.5 | 11.29 | 23.21 | 72.43 | 68 | 73 | 76 | 79 | 82 | 86 | 89 | 93 | 97 | 0.1206 | 397 | 1.136 | 33.29 | 11.66 | 2 | 0.2724 | 85 | 0.0754 | 0.90 | 2.811 | 0.6827 | 6932.2 | 592793 | 51500000 | 4550000000 | 0.3990 | 0.2389 | 0.0037 | 0.0000 | 0.0000 | 0.0032 | 0.0112 | 0.0000 | 0.0485 | 0.0096 | 0.0672 | 0.0737 | 0.1194 | 0.0833 | 0.0933 | 0.0481 | 0.1604 | 0.0705 | 0.4963 | 0.7115 | 0.0034 | 0.0000 | 0.0000 | 0.0032 | 0.0069 | 0.0000 | 0.0206 | 0.0096 | 0.0481 | 0.0737 | 0.0997 | 0.0833 | 0.0378 | 0.0481 | 0.0722 | 0.0705 | 0.7113 | 0.7115 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.2609 | 0.0000 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0120 | 0.0180 | 0.0299 | 0.0539 | 0.0898 | 0.2275 | 0.0958 | 0.1078 | 0.3653 | 5 | 6 | 8 | 8 | 9 | 10 | 11 | 12 | 16 | 0.2788 | 2.99 | 1.539 | 0.6666 | 5783.0 | 2740000 | 1470000000 | 851000000000 | 0.3576 | 0.2571 | 0.1333 | 0.2774 | 0.2167 | 0.1473 | 0.3500 | 0.1130 | 0.1833 | 0.1541 | 0.0833 | 0.1336 | 0.0333 | 0.1199 | 0.0000 | 0.0411 | 0.0000 | 0.0103 | 0.0000 | 0.0034 | 0.0217 | 0.1656 | 0.0072 | 0.0879 | 0.0109 | 0.0573 | 0.0217 | 0.0613 | 0.0435 | 0.0327 | 0.0942 | 0.0675 | 0.0471 | 0.0409 | 0.0870 | 0.0695 | 0.6667 | 0.4172 | 0.0000 | 0.0000 | 0.0093 | 0.0000 | 0.0046 | 0.0000 | 0.0139 | 0.0203 | 0.0509 | 0.0711 | 0.1111 | 0.0863 | 0.0556 | 0.0761 | 0.0787 | 0.0863 | 0.6759 | 0.6599 | 0.0042 | 0.0042 | 0.0211 | 0.0253 | 0.0506 | 0.0717 | 0.0717 | 0.0928 | 0.6582 |