High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 176 | 439 | | 2149 | 10252 | 192.6 | 59.91 | 8.87 | 3.44 | 120 | 133 | 148 | 165 | 184 | 205 | 228 | 254 | 283 | 0.0694 | 712 | 0.822 | 57.98 | 20.03 | 1 | 0.0814 | 175 | 0.0084 | 2.12 | 4.986 | 0.5414 | 40700.9 | 9310000 | 2270000000 | 578000000000 | 0.3740 | 0.2645 | 0.0013 | 0.0012 | 0.0076 | 0.0030 | 0.0076 | 0.0041 | 0.0278 | 0.0100 | 0.0682 | 0.0349 | 0.1174 | 0.0573 | 0.1023 | 0.0473 | 0.1452 | 0.0810 | 0.5227 | 0.7612 | 0.0000 | 0.0010 | 0.0043 | 0.0020 | 0.0021 | 0.0030 | 0.0100 | 0.0070 | 0.0242 | 0.0214 | 0.0356 | 0.0349 | 0.0342 | 0.0244 | 0.0456 | 0.0449 | 0.8439 | 0.8614 | 0.0000 | 0.0064 | 0.0000 | 0.0032 | 0.0065 | 0.0127 | 0.0196 | 0.0255 | 0.0344 | 0.0541 | 0.0687 | 0.0637 | 0.0507 | 0.0732 | 0.0589 | 0.0669 | 0.7610 | 0.6943 | 0.0000 | 0.0000 | 0.0072 | 0.0196 | 0.0319 | 0.0330 | 0.0484 | 0.0649 | 0.7951 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 11 | 13 | 0.0123 | 12.27 | 4.870 | 0.3144 | 90.5 | 1065.26 | 14510.9 | 227463 | 0.4586 | 0.1831 | 0.0295 | 0.0009 | 0.1028 | 0.0024 | 0.1962 | 0.0094 | 0.2565 | 0.0319 | 0.2244 | 0.0719 | 0.1268 | 0.1660 | 0.0511 | 0.2677 | 0.0112 | 0.2954 | 0.0016 | 0.1543 | 0.0050 | 0.0000 | 0.0247 | 0.0004 | 0.0691 | 0.0026 | 0.1247 | 0.0146 | 0.1520 | 0.0414 | 0.1628 | 0.1000 | 0.1487 | 0.1803 | 0.1348 | 0.2780 | 0.1782 | 0.3828 | 0.1256 | 0.1981 | 0.1426 | 0.1338 | 0.1343 | 0.1060 | 0.1181 | 0.0730 | 0.1121 | 0.0782 | 0.0895 | 0.0773 | 0.0642 | 0.0695 | 0.0701 | 0.0712 | 0.1434 | 0.1929 | 0.0242 | 0.0702 | 0.1099 | 0.1423 | 0.1381 | 0.1306 | 0.1204 | 0.1069 | 0.1574 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 424 | 598 | | 10118 | 27401 | 44.6 | 15.32 | 9.66 | 10.14 | 26 | 30 | 34 | 39 | 43 | 46 | 51 | 58 | 68 | 0.0697 | 1910 | 0.653 | 52.00 | 10.05 | 2 | 0.0153 | 155 | 0.0320 | 0.80 | 3.734 | 0.7116 | 2220.7 | 121956 | 7260000 | 460000000 | 0.4370 | 0.1928 | 0.0033 | 0.0009 | 0.0117 | 0.0021 | 0.0212 | 0.0062 | 0.0405 | 0.0162 | 0.0660 | 0.0337 | 0.0944 | 0.0462 | 0.1215 | 0.0617 | 0.1775 | 0.0854 | 0.4639 | 0.7475 | 0.0012 | 0.0004 | 0.0041 | 0.0011 | 0.0082 | 0.0029 | 0.0150 | 0.0080 | 0.0223 | 0.0197 | 0.0297 | 0.0256 | 0.0429 | 0.0335 | 0.0634 | 0.0478 | 0.8132 | 0.8611 | 0.0054 | 0.0041 | 0.0122 | 0.0117 | 0.0168 | 0.0233 | 0.0337 | 0.0425 | 0.0471 | 0.0487 | 0.0631 | 0.0720 | 0.0608 | 0.0822 | 0.0838 | 0.0864 | 0.6771 | 0.6292 | 0.0039 | 0.0100 | 0.0142 | 0.0234 | 0.0345 | 0.0395 | 0.0542 | 0.0860 | 0.7342 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 11 | 16 | 0.0607 | 0.27 | 1.084 | 0.3393 | 196.2 | 10715.8 | 1130000 | 163000000 | 0.5653 | 0.1216 | 0.0777 | 0.0043 | 0.1202 | 0.0147 | 0.1403 | 0.0416 | 0.1602 | 0.0819 | 0.1662 | 0.1200 | 0.1599 | 0.1529 | 0.1160 | 0.1781 | 0.0486 | 0.2087 | 0.0109 | 0.1979 | 0.0433 | 0.0019 | 0.0675 | 0.0095 | 0.0728 | 0.0304 | 0.0744 | 0.0626 | 0.0830 | 0.0967 | 0.0877 | 0.1232 | 0.0996 | 0.1307 | 0.1151 | 0.1503 | 0.3566 | 0.3946 | 0.0629 | 0.0327 | 0.0480 | 0.0262 | 0.0487 | 0.0276 | 0.0411 | 0.0316 | 0.0533 | 0.0584 | 0.0696 | 0.0784 | 0.0791 | 0.0835 | 0.1064 | 0.1232 | 0.4909 | 0.5384 | 0.0684 | 0.0635 | 0.0650 | 0.0662 | 0.0726 | 0.0769 | 0.0668 | 0.0896 | 0.4311 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 524 | 311 | | 7833 | 16316 | 159.4 | 129.05 | 84.65 | 174.06 | 65 | 76 | 86 | 97 | 114 | 131 | 150 | 185 | 382 | 0.0834 | 1360 | 1.188 | 60.96 | 23.71 | 5 | 0.0200 | 157 | 0.0057 | 7.18 | 5.903 | 0.4831 | 42052.4 | 16100000 | 7440000000 | 3750000000000 | 0.4134 | 0.2024 | 0.0022 | 0.0044 | 0.0039 | 0.0032 | 0.0061 | 0.0041 | 0.0335 | 0.0116 | 0.0754 | 0.0367 | 0.0972 | 0.0576 | 0.0972 | 0.0547 | 0.1056 | 0.0789 | 0.5788 | 0.7488 | 0.0012 | 0.0031 | 0.0021 | 0.0023 | 0.0027 | 0.0029 | 0.0140 | 0.0079 | 0.0273 | 0.0211 | 0.0334 | 0.0280 | 0.0404 | 0.0320 | 0.0507 | 0.0445 | 0.8282 | 0.8580 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0033 | 0.0000 | 0.0086 | 0.0022 | 0.0213 | 0.0230 | 0.0452 | 0.0445 | 0.0219 | 0.0208 | 0.0359 | 0.0408 | 0.8625 | 0.8687 | 0.0005 | 0.0039 | 0.0043 | 0.0096 | 0.0294 | 0.0487 | 0.0352 | 0.0545 | 0.8140 | 8 | 10 | 12 | 15 | 18 | 24 | 39 | 87 | 242 | 0.1992 | 8.64 | 2.988 | 0.7068 | 37461.6 | 26400000 | 22100000000 | 20600000000000 | 0.5330 | 0.1352 | 0.0090 | 0.0029 | 0.0336 | 0.0070 | 0.0493 | 0.0187 | 0.1087 | 0.0531 | 0.1659 | 0.0904 | 0.1839 | 0.1376 | 0.1390 | 0.1405 | 0.1312 | 0.1359 | 0.1794 | 0.4140 | 0.0005 | 0.0009 | 0.0029 | 0.0023 | 0.0029 | 0.0042 | 0.0098 | 0.0168 | 0.0383 | 0.0349 | 0.0554 | 0.0519 | 0.0449 | 0.0496 | 0.0660 | 0.0575 | 0.7794 | 0.7817 | 0.0021 | 0.0004 | 0.0017 | 0.0035 | 0.0045 | 0.0047 | 0.0141 | 0.0116 | 0.0497 | 0.0520 | 0.0783 | 0.0849 | 0.0583 | 0.0621 | 0.0852 | 0.0791 | 0.7060 | 0.7017 | 0.0009 | 0.0033 | 0.0045 | 0.0117 | 0.0415 | 0.0667 | 0.0505 | 0.0739 | 0.7471 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 838 | 827 | | 348 | 3785 | 69.6 | 9.59 | 7.19 | 2.56 | 58 | 61 | 63 | 66 | 69 | 71 | 74 | 78 | 83 | 0.1007 | 381 | 1.208 | 26.48 | 9.85 | 4 | 0.2011 | 70 | 0.0757 | 0.82 | 2.819 | 0.6940 | 4931.9 | 356260 | 26200000 | 1970000000 | 0.3634 | 0.2597 | 0.0033 | 0.0000 | 0.0100 | 0.0000 | 0.0133 | 0.0029 | 0.0332 | 0.0144 | 0.0698 | 0.0720 | 0.0997 | 0.0778 | 0.1096 | 0.0692 | 0.2359 | 0.1268 | 0.4252 | 0.6369 | 0.0030 | 0.0000 | 0.0000 | 0.0000 | 0.0090 | 0.0029 | 0.0181 | 0.0144 | 0.0633 | 0.0690 | 0.0843 | 0.0776 | 0.0663 | 0.0690 | 0.1506 | 0.1149 | 0.6054 | 0.6523 | 0.0323 | 1.0000 | 0.0000 | 0.0000 | 0.1613 | 0.0000 | 0.2258 | 0.0000 | 0.1613 | 0.0000 | 0.0968 | 0.0000 | 0.1935 | 0.0000 | 0.1290 | 0.0000 | 0.0000 | 0.0000 | 0.0123 | 0.0062 | 0.0247 | 0.0988 | 0.1358 | 0.1420 | 0.1235 | 0.1728 | 0.2840 | 4 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 0.0188 | 7.92 | 4.396 | 0.3583 | 58.2 | 526.12 | 5258.33 | 57582.2 | 0.4841 | 0.1761 | 0.0222 | 0.0039 | 0.0672 | 0.0054 | 0.1627 | 0.0219 | 0.2267 | 0.0409 | 0.2391 | 0.0828 | 0.1725 | 0.1441 | 0.0826 | 0.2539 | 0.0246 | 0.3015 | 0.0025 | 0.1456 | 0.0046 | 0.0003 | 0.0185 | 0.0006 | 0.0490 | 0.0059 | 0.0817 | 0.0178 | 0.1214 | 0.0422 | 0.1762 | 0.0716 | 0.1689 | 0.1446 | 0.1823 | 0.2904 | 0.1974 | 0.4267 | 0.1226 | 0.1623 | 0.1493 | 0.1451 | 0.1143 | 0.1019 | 0.1184 | 0.1036 | 0.0917 | 0.0829 | 0.0937 | 0.0760 | 0.0814 | 0.0864 | 0.0937 | 0.1330 | 0.1349 | 0.1088 | 0.0153 | 0.0463 | 0.0769 | 0.1084 | 0.1441 | 0.1724 | 0.1585 | 0.1298 | 0.1483 |
| SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 451 | | 11232 | 18145 | 198.9 | 80.62 | 6.13 | 2.92 | 96 | 118 | 138 | 163 | 190 | 224 | 254 | 281 | 308 | 0.0881 | 1598 | 0.402 | 135.09 | 20.03 | 6 | 0.0363 | 408 | 0.0017 | 7.54 | 6.630 | 0.3605 | 46068.3 | 11900000 | 3280000000 | 953000000000 | 0.4257 | 0.1921 | 0.0034 | 0.0015 | 0.0058 | 0.0030 | 0.0089 | 0.0074 | 0.0294 | 0.0164 | 0.0684 | 0.0406 | 0.1042 | 0.0619 | 0.1097 | 0.0584 | 0.1415 | 0.0780 | 0.5287 | 0.7328 | 0.0006 | 0.0003 | 0.0010 | 0.0001 | 0.0022 | 0.0029 | 0.0064 | 0.0067 | 0.0146 | 0.0168 | 0.0254 | 0.0283 | 0.0235 | 0.0230 | 0.0296 | 0.0320 | 0.8967 | 0.8898 | 0.0005 | 0.0025 | 0.0033 | 0.0051 | 0.0060 | 0.0132 | 0.0098 | 0.0229 | 0.0280 | 0.0467 | 0.0282 | 0.0642 | 0.0358 | 0.0778 | 0.0499 | 0.0999 | 0.8385 | 0.6677 | 0.0009 | 0.0007 | 0.0024 | 0.0073 | 0.0189 | 0.0239 | 0.0284 | 0.0375 | 0.8799 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.1305 | 0.44 | 1.002 | 0.4054 | 46.1 | 458.785 | 7687.85 | 234458 | 0.5483 | 0.1268 | 0.0123 | 0.0015 | 0.0555 | 0.0107 | 0.1399 | 0.0297 | 0.2151 | 0.0734 | 0.2476 | 0.1533 | 0.1919 | 0.2308 | 0.1031 | 0.2579 | 0.0306 | 0.1797 | 0.0042 | 0.0631 | 0.0008 | 0.0001 | 0.0083 | 0.0014 | 0.0270 | 0.0074 | 0.0633 | 0.0263 | 0.1189 | 0.0658 | 0.1643 | 0.1156 | 0.2017 | 0.2003 | 0.2201 | 0.2840 | 0.1956 | 0.2992 | 0.1197 | 0.2233 | 0.1816 | 0.2100 | 0.1733 | 0.1903 | 0.1579 | 0.1256 | 0.1231 | 0.0803 | 0.0916 | 0.0538 | 0.0625 | 0.0439 | 0.0525 | 0.0381 | 0.0379 | 0.0347 | 0.0066 | 0.0454 | 0.0962 | 0.1383 | 0.1787 | 0.1873 | 0.1512 | 0.1164 | 0.0797 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1243 | 854 | | 722 | 7966 | 63.7 | 17.26 | 99.18 | 192.37 | 47 | 51 | 53 | 56 | 60 | 63 | 68 | 74 | 85 | 0.0734 | 585 | 0.421 | 183.11 | 37.80 | 0 | 0.8726 | 630 | 0.0093 | 10.56 | 5.018 | 0.3434 | 4360.7 | 324711 | 26600000 | 2420000000 | 0.4665 | 0.1732 | 0.0048 | 0.0000 | 0.0238 | 0.0000 | 0.0499 | 0.0060 | 0.0950 | 0.0255 | 0.1354 | 0.0510 | 0.1853 | 0.0990 | 0.1663 | 0.1049 | 0.1663 | 0.1094 | 0.1734 | 0.6042 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0128 | 0.0028 | 0.0475 | 0.0097 | 0.0786 | 0.0444 | 0.1408 | 0.0819 | 0.1261 | 0.0611 | 0.1481 | 0.0833 | 0.4388 | 0.7167 | 0.0000 | 0.0000 | 0.0317 | 0.0377 | 0.0159 | 0.0755 | 0.0952 | 0.0755 | 0.1825 | 0.3019 | 0.1825 | 0.1321 | 0.1508 | 0.0566 | 0.1508 | 0.2075 | 0.1905 | 0.1132 | 0.0036 | 0.0180 | 0.0288 | 0.0791 | 0.1259 | 0.1691 | 0.1295 | 0.1511 | 0.2950 | 10 | 12 | 14 | 15 | 17 | 19 | 31 | 113 | 371 | 0.1151 | 73.14 | 4.084 | 0.5429 | 46837.2 | 32700000 | 27500000000 | 26300000000000 | 0.6007 | 0.1115 | 0.2664 | 0.0211 | 0.4953 | 0.1607 | 0.2103 | 0.5011 | 0.0280 | 0.1882 | 0.0000 | 0.0782 | 0.0000 | 0.0338 | 0.0000 | 0.0127 | 0.0000 | 0.0042 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0022 | 0.0015 | 0.0056 | 0.0036 | 0.0185 | 0.0247 | 0.0888 | 0.0781 | 0.1355 | 0.1183 | 0.0748 | 0.0848 | 0.1231 | 0.1177 | 0.5509 | 0.5707 | 0.0006 | 0.0007 | 0.0013 | 0.0041 | 0.0083 | 0.0082 | 0.0230 | 0.0211 | 0.0856 | 0.0958 | 0.1540 | 0.1501 | 0.0818 | 0.0795 | 0.1176 | 0.1291 | 0.5278 | 0.5115 | 0.0012 | 0.0024 | 0.0054 | 0.0198 | 0.0929 | 0.1360 | 0.0827 | 0.1210 | 0.5386 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 146 | 51 | | 354 | 2232 | 83.5 | 10.81 | 232.77 | 142.92 | 70 | 73 | 77 | 80 | 83 | 86 | 89 | 94 | 99 | 0.1223 | 273 | 1.033 | 88.84 | 22.85 | 0 | 0.5791 | 205 | 0.0101 | 9.66 | 4.753 | 0.3349 | 7088.7 | 611712 | 53600000 | 4780000000 | 0.4194 | 0.1966 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0130 | 0.0028 | 0.0357 | 0.0085 | 0.0779 | 0.0397 | 0.1331 | 0.1473 | 0.1331 | 0.0368 | 0.2110 | 0.0822 | 0.3929 | 0.6827 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0030 | 0.0028 | 0.0178 | 0.0056 | 0.0562 | 0.0424 | 0.1124 | 0.1441 | 0.0621 | 0.0339 | 0.1213 | 0.0763 | 0.6243 | 0.6949 | 0.0000 | 1.0000 | 0.1000 | 0.0000 | 0.3667 | 0.0000 | 0.1000 | 0.0000 | 0.1667 | 0.0000 | 0.1333 | 0.0000 | 0.0667 | 0.0000 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0430 | 0.0699 | 0.1505 | 0.1720 | 0.1290 | 0.1559 | 0.2688 | 68 | 106 | 142 | 176 | 210 | 248 | 292 | 342 | 423 | 0.0013 | 85.74 | 6.901 | 0.1836 | 74597.8 | 29500000 | 13700000000 | 7190000000000 | 0.4379 | 0.1909 | 0.0169 | 0.0028 | 0.0639 | 0.0075 | 0.1899 | 0.0197 | 0.2199 | 0.0563 | 0.1748 | 0.1315 | 0.1485 | 0.1840 | 0.0846 | 0.1897 | 0.0639 | 0.1615 | 0.0376 | 0.2469 | 0.0008 | 0.0013 | 0.0016 | 0.0019 | 0.0055 | 0.0044 | 0.0181 | 0.0120 | 0.0604 | 0.0405 | 0.1319 | 0.0790 | 0.0981 | 0.0765 | 0.1389 | 0.0967 | 0.5447 | 0.6877 | 0.0013 | 0.0039 | 0.0054 | 0.0135 | 0.0148 | 0.0271 | 0.0620 | 0.0832 | 0.1334 | 0.1605 | 0.1536 | 0.1741 | 0.1361 | 0.1586 | 0.1860 | 0.1470 | 0.3073 | 0.2321 | 0.0000 | 0.0020 | 0.0121 | 0.0302 | 0.1099 | 0.1532 | 0.1149 | 0.1734 | 0.4042 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 206 | 921 | | 453 | 2987 | 114.8 | 45.79 | 54.07 | 106.69 | 60 | 72 | 83 | 92 | 107 | 124 | 140 | 163 | 186 | 0.1145 | 342 | 0.878 | 44.91 | 11.18 | 2 | 0.2517 | 114 | 0.0028 | 90.22 | 5.942 | 0.1266 | 15262.5 | 2270000 | 364000000 | 61700000000 | 0.3487 | 0.2630 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.1136 | 0.0107 | 0.1894 | 0.0143 | 0.2803 | 0.0964 | 0.1667 | 0.1607 | 0.1212 | 0.1214 | 0.0833 | 0.2250 | 0.0455 | 0.3714 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0217 | 0.0080 | 0.0797 | 0.0507 | 0.0870 | 0.0667 | 0.0833 | 0.0453 | 0.1232 | 0.0907 | 0.6051 | 0.7360 | 0.0000 | 0.0105 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0417 | 0.0526 | 0.1389 | 0.1263 | 0.1181 | 0.1895 | 0.1042 | 0.1158 | 0.1458 | 0.1579 | 0.4444 | 0.3474 | 0.0000 | 0.0000 | 0.0100 | 0.0348 | 0.0796 | 0.1095 | 0.0945 | 0.0746 | 0.5970 | 19 | 21 | 22 | 23 | 25 | 27 | 30 | 40 | 83 | 0.1621 | 4.97 | 2.567 | 0.7206 | 14301.8 | 8310000 | 5840000000 | 4430000000000 | 0.6250 | 0.1113 | 0.0402 | 0.0406 | 0.1609 | 0.0449 | 0.1954 | 0.0684 | 0.2471 | 0.0983 | 0.1667 | 0.1581 | 0.1207 | 0.1859 | 0.0517 | 0.1838 | 0.0115 | 0.1496 | 0.0057 | 0.0705 | 0.0018 | 0.0239 | 0.0164 | 0.0239 | 0.0236 | 0.0290 | 0.0436 | 0.0365 | 0.1127 | 0.0982 | 0.1145 | 0.1159 | 0.0836 | 0.0882 | 0.1309 | 0.1461 | 0.4727 | 0.4383 | 0.0080 | 0.0000 | 0.0133 | 0.0215 | 0.0080 | 0.0000 | 0.0372 | 0.0307 | 0.1197 | 0.1350 | 0.1383 | 0.1350 | 0.0851 | 0.0890 | 0.1463 | 0.1442 | 0.4441 | 0.4448 | 0.0022 | 0.0130 | 0.0152 | 0.0304 | 0.1326 | 0.1152 | 0.0870 | 0.1413 | 0.4630 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 553 | 850 | | 1687 | 2459 | 300.5 | 204.06 | 15.65 | 29.61 | 110 | 143 | 172 | 196 | 226 | 271 | 333 | 444 | 654 | 0.1684 | 414 | 0.726 | 89.00 | 15.23 | 2 | 0.1114 | 188 | 0.0012 | 52.86 | 6.939 | 0.2192 | 131887.0 | 75200000 | 49500000000 | 35300000000000 | 0.3308 | 0.2934 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0059 | 0.0039 | 0.0676 | 0.0130 | 0.1618 | 0.0649 | 0.2176 | 0.1104 | 0.1294 | 0.0909 | 0.1147 | 0.1078 | 0.3029 | 0.6091 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0102 | 0.0089 | 0.0422 | 0.0337 | 0.0588 | 0.0452 | 0.0409 | 0.0425 | 0.0537 | 0.0558 | 0.7941 | 0.8113 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0045 | 0.0000 | 0.0045 | 0.0056 | 0.0543 | 0.0446 | 0.0860 | 0.0864 | 0.0294 | 0.0362 | 0.0633 | 0.0585 | 0.7579 | 0.7688 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0434 | 0.0701 | 0.0484 | 0.0668 | 0.7613 | 6 | 7 | 8 | 9 | 10 | 11 | 11 | 13 | 16 | 0.6120 | 0.70 | 1.147 | 0.8761 | 1121.1 | 209476 | 49200000 | 12700000000 | 0.5069 | 0.1463 | 0.1731 | 0.0340 | 0.1621 | 0.0635 | 0.1264 | 0.1020 | 0.1978 | 0.1422 | 0.1264 | 0.1592 | 0.1209 | 0.1494 | 0.0604 | 0.1476 | 0.0275 | 0.1127 | 0.0055 | 0.0894 | 0.1136 | 0.0296 | 0.0971 | 0.0553 | 0.0531 | 0.0872 | 0.1081 | 0.1153 | 0.1117 | 0.1379 | 0.1026 | 0.1254 | 0.0861 | 0.1347 | 0.1081 | 0.1160 | 0.2198 | 0.1986 | 0.0110 | 0.0000 | 0.0385 | 0.0060 | 0.0055 | 0.0060 | 0.0220 | 0.0482 | 0.1154 | 0.1024 | 0.1264 | 0.1265 | 0.1154 | 0.1205 | 0.1209 | 0.1325 | 0.4451 | 0.4578 | 0.0618 | 0.0579 | 0.0734 | 0.0463 | 0.0888 | 0.1004 | 0.0811 | 0.1197 | 0.3707 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 56 | 911 | | 384 | 7332 | 60.6 | 12.76 | 165.06 | 118.18 | 45 | 50 | 53 | 57 | 60 | 63 | 67 | 71 | 76 | 0.0614 | 450 | 0.519 | 130.54 | 26.91 | 0 | 1.0260 | 394 | 0.0099 | 9.19 | 4.826 | 0.3167 | 3828.9 | 252540 | 17400000 | 1250000000 | 0.4554 | 0.1729 | 0.0036 | 0.0000 | 0.0109 | 0.0028 | 0.0182 | 0.0055 | 0.0691 | 0.0194 | 0.1309 | 0.0720 | 0.1709 | 0.1219 | 0.1782 | 0.0914 | 0.2000 | 0.1607 | 0.2182 | 0.5263 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0093 | 0.0027 | 0.0247 | 0.0107 | 0.0957 | 0.0587 | 0.1235 | 0.1147 | 0.1173 | 0.0667 | 0.1420 | 0.1333 | 0.4877 | 0.6107 | 0.1020 | 0.0000 | 0.0612 | 0.1429 | 0.1224 | 0.0714 | 0.1020 | 0.3571 | 0.1633 | 0.2857 | 0.1837 | 0.0714 | 0.1633 | 0.0714 | 0.0612 | 0.0000 | 0.0408 | 0.0000 | 0.0053 | 0.0000 | 0.0106 | 0.0638 | 0.1596 | 0.1702 | 0.1596 | 0.1915 | 0.2394 | 18 | 37 | 71 | 117 | 158 | 195 | 232 | 274 | 329 | 0.0075 | 22.50 | 6.081 | 0.3343 | 41207.1 | 12200000 | 3970000000 | 1400000000000 | 0.4642 | 0.1955 | 0.0148 | 0.0016 | 0.1134 | 0.0089 | 0.1997 | 0.0335 | 0.1935 | 0.0895 | 0.1671 | 0.1734 | 0.1507 | 0.1952 | 0.0870 | 0.1593 | 0.0583 | 0.1613 | 0.0155 | 0.1774 | 0.0000 | 0.0000 | 0.0005 | 0.0013 | 0.0024 | 0.0011 | 0.0128 | 0.0077 | 0.0443 | 0.0302 | 0.0775 | 0.0562 | 0.0828 | 0.0523 | 0.1239 | 0.0826 | 0.6558 | 0.7687 | 0.0003 | 0.0023 | 0.0052 | 0.0099 | 0.0108 | 0.0185 | 0.0241 | 0.0468 | 0.0927 | 0.1342 | 0.1524 | 0.1640 | 0.1405 | 0.1486 | 0.1552 | 0.1721 | 0.4188 | 0.3036 | 0.0011 | 0.0025 | 0.0040 | 0.0178 | 0.0627 | 0.1136 | 0.1110 | 0.1627 | 0.5246 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 481 | 100 | | 7950 | 9207 | 278.6 | 129.42 | 10.26 | 12.06 | 144 | 163 | 187 | 215 | 241 | 273 | 314 | 413 | 495 | 0.0924 | 851 | 0.695 | 94.53 | 15.03 | 6 | 0.0267 | 212 | 0.0018 | 9.35 | 6.724 | 0.3596 | 94338.5 | 37400000 | 16500000000 | 7810000000000 | 0.4212 | 0.2162 | 0.0009 | 0.0016 | 0.0013 | 0.0016 | 0.0068 | 0.0043 | 0.0175 | 0.0086 | 0.0554 | 0.0374 | 0.0967 | 0.0491 | 0.0797 | 0.0423 | 0.1121 | 0.0623 | 0.6297 | 0.7930 | 0.0004 | 0.0011 | 0.0007 | 0.0010 | 0.0027 | 0.0027 | 0.0064 | 0.0047 | 0.0202 | 0.0199 | 0.0282 | 0.0236 | 0.0285 | 0.0216 | 0.0407 | 0.0308 | 0.8721 | 0.8946 | 0.0009 | 0.0000 | 0.0009 | 0.0000 | 0.0028 | 0.0017 | 0.0070 | 0.0091 | 0.0167 | 0.0205 | 0.0423 | 0.0400 | 0.0265 | 0.0377 | 0.0307 | 0.0354 | 0.8721 | 0.8556 | 0.0010 | 0.0016 | 0.0049 | 0.0092 | 0.0191 | 0.0384 | 0.0309 | 0.0427 | 0.8521 | 3 | 5 | 5 | 6 | 7 | 8 | 9 | 11 | 19 | 0.1322 | 0.45 | 1.509 | 0.5124 | 250.6 | 12213 | 813301 | 62700000 | 0.5153 | 0.1526 | 0.0886 | 0.0079 | 0.2162 | 0.0407 | 0.2503 | 0.0797 | 0.2088 | 0.1421 | 0.1362 | 0.1824 | 0.0696 | 0.1959 | 0.0225 | 0.1743 | 0.0078 | 0.1275 | 0.0000 | 0.0493 | 0.0425 | 0.0045 | 0.1012 | 0.0274 | 0.1320 | 0.0540 | 0.1129 | 0.0995 | 0.0975 | 0.1431 | 0.0935 | 0.1554 | 0.0649 | 0.1304 | 0.0728 | 0.1196 | 0.2827 | 0.2662 | 0.0790 | 0.0376 | 0.0515 | 0.0295 | 0.0334 | 0.0302 | 0.0322 | 0.0376 | 0.0632 | 0.0604 | 0.0971 | 0.1150 | 0.0872 | 0.0825 | 0.0989 | 0.1098 | 0.4576 | 0.4974 | 0.1005 | 0.0895 | 0.0781 | 0.0561 | 0.0570 | 0.0875 | 0.0557 | 0.0858 | 0.3897 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1057 | 334 | | 2802 | 7296 | 92.2 | 25.90 | 117.02 | 76.72 | 61 | 72 | 78 | 83 | 89 | 94 | 102 | 114 | 128 | 0.0968 | 706 | 0.875 | 120.79 | 34.99 | 2 | 0.1071 | 300 | 0.0040 | 10.09 | 5.865 | 0.3358 | 9174.8 | 979929 | 112000000 | 13500000000 | 0.4595 | 0.1918 | 0.0026 | 0.0000 | 0.0019 | 0.0000 | 0.0136 | 0.0034 | 0.0285 | 0.0107 | 0.0783 | 0.0390 | 0.1462 | 0.0642 | 0.1481 | 0.0723 | 0.1708 | 0.0985 | 0.4101 | 0.7119 | 0.0005 | 0.0000 | 0.0009 | 0.0000 | 0.0055 | 0.0027 | 0.0110 | 0.0050 | 0.0375 | 0.0249 | 0.0536 | 0.0345 | 0.0659 | 0.0383 | 0.0893 | 0.0509 | 0.7358 | 0.8437 | 0.0031 | 0.0036 | 0.0047 | 0.0182 | 0.0219 | 0.0400 | 0.0470 | 0.0800 | 0.0799 | 0.1091 | 0.1270 | 0.1564 | 0.0831 | 0.1273 | 0.1191 | 0.1309 | 0.5141 | 0.3345 | 0.0057 | 0.0123 | 0.0188 | 0.0286 | 0.0645 | 0.0989 | 0.0784 | 0.1078 | 0.5850 | 35 | 49 | 64 | 82 | 101 | 122 | 146 | 178 | 225 | 0.0071 | 10.21 | 5.520 | 0.4012 | 19579.1 | 4150000 | 1040000000 | 297000000000 | 0.5233 | 0.1494 | 0.0087 | 0.0019 | 0.0570 | 0.0036 | 0.1531 | 0.0185 | 0.1866 | 0.0588 | 0.2102 | 0.1426 | 0.1618 | 0.1929 | 0.1054 | 0.1643 | 0.0688 | 0.1647 | 0.0484 | 0.2527 | 0.0015 | 0.0006 | 0.0028 | 0.0017 | 0.0081 | 0.0062 | 0.0233 | 0.0159 | 0.0535 | 0.0453 | 0.0933 | 0.0805 | 0.0813 | 0.0620 | 0.1102 | 0.0836 | 0.6260 | 0.7042 | 0.0013 | 0.0023 | 0.0047 | 0.0085 | 0.0214 | 0.0194 | 0.0343 | 0.0461 | 0.0909 | 0.1071 | 0.1496 | 0.1720 | 0.1127 | 0.1236 | 0.1444 | 0.1384 | 0.4406 | 0.3827 | 0.0026 | 0.0058 | 0.0125 | 0.0295 | 0.0655 | 0.1210 | 0.1079 | 0.1339 | 0.5213 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 159 | 548 | | 379 | 3429 | 61.1 | 11.87 | 9.11 | 3.08 | 46 | 49 | 53 | 56 | 61 | 64 | 69 | 74 | 78 | 0.1105 | 379 | 1.104 | 39.12 | 14.21 | 3 | 0.2797 | 106 | 0.0614 | 0.78 | 2.978 | 0.7032 | 3871.4 | 253941 | 17200000 | 1190000000 | 0.4114 | 0.2187 | 0.0000 | 0.0000 | 0.0338 | 0.0000 | 0.0211 | 0.0027 | 0.0717 | 0.0133 | 0.1392 | 0.0398 | 0.1477 | 0.0928 | 0.1477 | 0.0398 | 0.1181 | 0.0955 | 0.3207 | 0.7162 | 0.0000 | 0.0000 | 0.0223 | 0.0000 | 0.0096 | 0.0026 | 0.0287 | 0.0132 | 0.0510 | 0.0396 | 0.0701 | 0.0923 | 0.0605 | 0.0343 | 0.0764 | 0.0686 | 0.6815 | 0.7493 | 0.0000 | 0.0000 | 0.0000 | 1.0000 | 0.0519 | 0.0000 | 0.0649 | 0.0000 | 0.2208 | 0.0000 | 0.1818 | 0.0000 | 0.2078 | 0.0000 | 0.1688 | 0.0000 | 0.1039 | 0.0000 | 0.0000 | 0.0209 | 0.0105 | 0.0419 | 0.0995 | 0.0942 | 0.1047 | 0.1152 | 0.5131 | 5 | 7 | 7 | 8 | 9 | 10 | 10 | 11 | 13 | 0.0137 | 13.19 | 4.745 | 0.3048 | 92.4 | 1038.16 | 12866.9 | 175722 | 0.4767 | 0.1774 | 0.0306 | 0.0011 | 0.0977 | 0.0053 | 0.1939 | 0.0174 | 0.2558 | 0.0474 | 0.2165 | 0.0913 | 0.1348 | 0.1588 | 0.0547 | 0.2421 | 0.0160 | 0.2736 | 0.0000 | 0.1629 | 0.0040 | 0.0000 | 0.0215 | 0.0007 | 0.0553 | 0.0059 | 0.0975 | 0.0180 | 0.1615 | 0.0475 | 0.1708 | 0.0992 | 0.1550 | 0.1490 | 0.1519 | 0.2449 | 0.1826 | 0.4348 | 0.1258 | 0.1928 | 0.1479 | 0.1639 | 0.1336 | 0.1470 | 0.1291 | 0.1012 | 0.1049 | 0.1036 | 0.0894 | 0.1108 | 0.0993 | 0.0916 | 0.1038 | 0.0675 | 0.0662 | 0.0217 | 0.0221 | 0.0550 | 0.1024 | 0.1185 | 0.1422 | 0.1212 | 0.1315 | 0.1245 | 0.1827 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 181 | 254 | | 1614 | 11324 | 1117.5 | 296.73 | 9.91 | 3.01 | 735 | 828 | 914 | 1000 | 1089 | 1176 | 1265 | 1423 | 1565 | 0.0770 | 872 | 1.072 | 79.08 | 22.56 | 2 | 0.1121 | 181 | 0.0011 | 52.02 | 6.977 | 0.1957 | 1340000.0 | 1700000000 | 2270000000000 | 3.16E+15 | 0.3925 | 0.2330 | 0.0013 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0043 | 0.0090 | 0.0078 | 0.0859 | 0.0456 | 0.1538 | 0.0820 | 0.1013 | 0.0520 | 0.1115 | 0.0834 | 0.5372 | 0.7242 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0043 | 0.0058 | 0.0445 | 0.0358 | 0.0676 | 0.0588 | 0.0360 | 0.0371 | 0.0668 | 0.0543 | 0.7800 | 0.8056 | 0.0000 | 0.0000 | 0.0000 | 0.0062 | 0.0000 | 0.0124 | 0.0103 | 0.0248 | 0.0490 | 0.0745 | 0.0979 | 0.1242 | 0.0515 | 0.0745 | 0.0670 | 0.1304 | 0.7242 | 0.5528 | 0.0000 | 0.0000 | 0.0013 | 0.0066 | 0.0584 | 0.0717 | 0.0491 | 0.0704 | 0.7424 | 6 | 7 | 8 | 9 | 10 | 11 | 11 | 12 | 14 | 0.4427 | 0.33 | 0.894 | 0.7893 | 107.3 | 1247.66 | 15428.7 | 201459 | 0.5329 | 0.1343 | 0.0090 | 0.0001 | 0.0432 | 0.0015 | 0.1219 | 0.0064 | 0.2092 | 0.0237 | 0.2630 | 0.0647 | 0.2046 | 0.1320 | 0.1129 | 0.2428 | 0.0316 | 0.3164 | 0.0048 | 0.2124 | 0.0001 | 0.0000 | 0.0019 | 0.0002 | 0.0112 | 0.0008 | 0.0360 | 0.0079 | 0.0843 | 0.0254 | 0.1595 | 0.0409 | 0.2364 | 0.0926 | 0.2711 | 0.2669 | 0.1995 | 0.5654 | 0.0875 | 0.2991 | 0.1970 | 0.2991 | 0.2239 | 0.2057 | 0.2071 | 0.1218 | 0.1517 | 0.0503 | 0.0847 | 0.0160 | 0.0376 | 0.0044 | 0.0092 | 0.0036 | 0.0012 | 0.0000 | 0.0072 | 0.0439 | 0.0969 | 0.1605 | 0.2046 | 0.1989 | 0.1608 | 0.0959 | 0.0313 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1140 | 800 | | 415 | 10014 | 37.5 | 8.37 | 298.79 | 356.44 | 26 | 30 | 32 | 35 | 37 | 40 | 42 | 45 | 48 | 0.0520 | 521 | 0.700 | 202.20 | 35.61 | 2 | 1.1663 | 484 | 0.0170 | 4.33 | 4.301 | 0.4484 | 1479.7 | 60857.1 | 2600000 | 115000000 | 0.3546 | 0.2708 | 0.0000 | 0.0000 | 0.0083 | 0.0000 | 0.0373 | 0.0025 | 0.1037 | 0.0176 | 0.2241 | 0.0529 | 0.2033 | 0.0856 | 0.1867 | 0.1058 | 0.1743 | 0.1738 | 0.0622 | 0.5617 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0127 | 0.0025 | 0.0538 | 0.0173 | 0.0854 | 0.0519 | 0.0918 | 0.0765 | 0.1076 | 0.0914 | 0.1424 | 0.1136 | 0.5032 | 0.6469 | 0.0533 | 0.2500 | 0.0800 | 0.0000 | 0.0533 | 0.0000 | 0.2000 | 0.3750 | 0.1600 | 0.2500 | 0.1467 | 0.1250 | 0.2133 | 0.0000 | 0.0533 | 0.0000 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0291 | 0.0825 | 0.1311 | 0.1602 | 0.1408 | 0.1748 | 0.2816 | 16 | 19 | 26 | 56 | 134 | 250 | 397 | 574 | 843 | 0.0362 | 50.93 | 5.899 | 0.4283 | 216312.0 | 203000000 | 220000000000 | 261000000000000 | 0.5151 | 0.1616 | 0.0713 | 0.0006 | 0.1940 | 0.0107 | 0.2691 | 0.1146 | 0.2078 | 0.1740 | 0.1352 | 0.1960 | 0.0701 | 0.1829 | 0.0250 | 0.1140 | 0.0163 | 0.1146 | 0.0113 | 0.0926 | 0.0002 | 0.0000 | 0.0002 | 0.0009 | 0.0022 | 0.0018 | 0.0115 | 0.0112 | 0.0583 | 0.0497 | 0.0937 | 0.0790 | 0.0718 | 0.0645 | 0.0976 | 0.0919 | 0.6644 | 0.7012 | 0.0003 | 0.0007 | 0.0018 | 0.0045 | 0.0055 | 0.0111 | 0.0210 | 0.0236 | 0.0735 | 0.0748 | 0.1104 | 0.1219 | 0.0921 | 0.0890 | 0.1052 | 0.1126 | 0.5902 | 0.5618 | 0.0003 | 0.0005 | 0.0027 | 0.0156 | 0.0648 | 0.1058 | 0.0826 | 0.1017 | 0.6260 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 693 | | 1758 | 9747 | 194.5 | 65.03 | 7.39 | 2.56 | 126 | 140 | 153 | 164 | 173 | 189 | 216 | 254 | 297 | 0.0806 | 786 | 1.223 | 29.83 | 11.66 | 2 | 0.0438 | 77 | 0.0089 | 2.56 | 5.059 | 0.5219 | 42048.1 | 10100000 | 2640000000 | 742000000000 | 0.3576 | 0.2730 | 0.0013 | 0.0000 | 0.0053 | 0.0007 | 0.0093 | 0.0043 | 0.0200 | 0.0100 | 0.0787 | 0.0400 | 0.1267 | 0.0557 | 0.1067 | 0.0550 | 0.1440 | 0.0764 | 0.5080 | 0.7580 | 0.0008 | 0.0000 | 0.0034 | 0.0006 | 0.0050 | 0.0024 | 0.0101 | 0.0078 | 0.0378 | 0.0269 | 0.0512 | 0.0305 | 0.0419 | 0.0335 | 0.0680 | 0.0449 | 0.7819 | 0.8533 | 0.0023 | 0.0037 | 0.0000 | 0.0037 | 0.0000 | 0.0000 | 0.0090 | 0.0186 | 0.0498 | 0.0520 | 0.0611 | 0.0892 | 0.0452 | 0.0520 | 0.0656 | 0.0743 | 0.7670 | 0.7063 | 0.0000 | 0.0000 | 0.0030 | 0.0076 | 0.0318 | 0.0636 | 0.0394 | 0.0561 | 0.7985 | 4 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0172 | 8.20 | 4.461 | 0.3585 | 61.1 | 562.508 | 5723.84 | 64032.1 | 0.4837 | 0.1687 | 0.0143 | 0.0020 | 0.0491 | 0.0072 | 0.1154 | 0.0186 | 0.1968 | 0.0459 | 0.2244 | 0.0938 | 0.2015 | 0.1724 | 0.1356 | 0.2637 | 0.0542 | 0.2652 | 0.0087 | 0.1312 | 0.0012 | 0.0000 | 0.0093 | 0.0006 | 0.0270 | 0.0038 | 0.0627 | 0.0130 | 0.1007 | 0.0342 | 0.1357 | 0.0750 | 0.1749 | 0.1500 | 0.2022 | 0.2720 | 0.2862 | 0.4515 | 0.1173 | 0.1778 | 0.1454 | 0.1541 | 0.1396 | 0.1171 | 0.1150 | 0.1141 | 0.1015 | 0.0801 | 0.0904 | 0.0898 | 0.0869 | 0.0746 | 0.0800 | 0.0728 | 0.1238 | 0.1195 | 0.0077 | 0.0301 | 0.0649 | 0.1143 | 0.1463 | 0.1559 | 0.1546 | 0.1313 | 0.1950 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 735 | 406 | | 428 | 1601 | 77.0 | 10.85 | 11.27 | 14.00 | 65 | 67 | 70 | 72 | 75 | 77 | 82 | 86 | 93 | 0.1643 | 263 | 0.708 | 113.88 | 25.02 | 1 | 0.6636 | 284 | 0.0441 | 1.02 | 3.411 | 0.6516 | 6040.7 | 483894 | 39600000 | 3310000000 | 0.3996 | 0.2382 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0053 | 0.0024 | 0.0718 | 0.0447 | 0.1011 | 0.0753 | 0.0638 | 0.0400 | 0.1277 | 0.0918 | 0.6303 | 0.7435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0047 | 0.0023 | 0.0498 | 0.0444 | 0.0687 | 0.0724 | 0.0332 | 0.0304 | 0.0782 | 0.0748 | 0.7654 | 0.7734 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 1.0000 | 0.0217 | 0.0000 | 0.1739 | 0.0000 | 0.1304 | 0.0000 | 0.1304 | 0.0000 | 0.1522 | 0.0000 | 0.3478 | 0.0000 | 0.0053 | 0.0000 | 0.0105 | 0.0474 | 0.0579 | 0.1000 | 0.0947 | 0.1263 | 0.5579 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 12 | 15 | 0.6009 | 2.10 | 1.178 | 0.8849 | 322.9 | 27681.3 | 3820000 | 619000000 | 0.6572 | 0.0788 | 0.0682 | 0.0020 | 0.1326 | 0.0188 | 0.1111 | 0.0683 | 0.1189 | 0.0960 | 0.1598 | 0.1317 | 0.1774 | 0.1545 | 0.1365 | 0.1535 | 0.0741 | 0.1723 | 0.0214 | 0.2030 | 0.0477 | 0.0017 | 0.0846 | 0.0145 | 0.0682 | 0.0513 | 0.0628 | 0.0803 | 0.1010 | 0.1103 | 0.1173 | 0.1350 | 0.1119 | 0.1325 | 0.1364 | 0.1556 | 0.2701 | 0.3188 | 0.0591 | 0.0313 | 0.0727 | 0.0313 | 0.0364 | 0.0313 | 0.0591 | 0.0625 | 0.0773 | 0.1188 | 0.1545 | 0.1688 | 0.1364 | 0.1813 | 0.1909 | 0.2125 | 0.2136 | 0.1625 | 0.0592 | 0.0547 | 0.0661 | 0.0957 | 0.1207 | 0.1276 | 0.1116 | 0.1344 | 0.2301 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 576 | 951 | | 438 | 2028 | 54.0 | 7.53 | 156.62 | 225.49 | 45 | 48 | 49 | 51 | 54 | 55 | 57 | 60 | 63 | 0.1686 | 342 | 0.895 | 78.01 | 22.20 | 1 | 0.4566 | 200 | 0.0096 | 10.55 | 4.855 | 0.3142 | 2971.3 | 166797 | 9560000 | 559000000 | 0.3875 | 0.2379 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0023 | 0.0262 | 0.0092 | 0.0945 | 0.0624 | 0.1260 | 0.0901 | 0.1811 | 0.0693 | 0.2520 | 0.1085 | 0.3123 | 0.6582 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0023 | 0.0193 | 0.0091 | 0.0578 | 0.0594 | 0.0988 | 0.0868 | 0.1012 | 0.0548 | 0.1518 | 0.0868 | 0.5639 | 0.7009 | 0.1765 | 0.0000 | 0.1765 | 0.2000 | 0.0588 | 0.2000 | 0.1765 | 0.6000 | 0.1176 | 0.0000 | 0.0294 | 0.0000 | 0.1765 | 0.0000 | 0.0882 | 0.0000 | 0.0000 | 0.0000 | 0.0136 | 0.0318 | 0.0227 | 0.0773 | 0.1364 | 0.1364 | 0.1500 | 0.2091 | 0.2227 | 17 | 21 | 28 | 41 | 64 | 99 | 142 | 241 | 425 | 0.0260 | 58.20 | 5.100 | 0.4350 | 75349.7 | 58100000 | 55000000000 | 57800000000000 | 0.4831 | 0.1439 | 0.1056 | 0.0000 | 0.2609 | 0.0221 | 0.2050 | 0.1838 | 0.0870 | 0.1569 | 0.1242 | 0.1936 | 0.0870 | 0.1201 | 0.0683 | 0.0760 | 0.0435 | 0.1176 | 0.0186 | 0.1299 | 0.0030 | 0.0000 | 0.0030 | 0.0036 | 0.0151 | 0.0059 | 0.0256 | 0.0119 | 0.0935 | 0.0973 | 0.1704 | 0.1269 | 0.0905 | 0.0973 | 0.1297 | 0.1329 | 0.4691 | 0.5243 | 0.0020 | 0.0000 | 0.0060 | 0.0069 | 0.0159 | 0.0207 | 0.0239 | 0.0345 | 0.1076 | 0.1310 | 0.1853 | 0.1816 | 0.1036 | 0.0989 | 0.1474 | 0.1402 | 0.4084 | 0.3862 | 0.0000 | 0.0035 | 0.0159 | 0.0265 | 0.1044 | 0.1805 | 0.0973 | 0.1274 | 0.4442 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 762 | 189 | | 1376 | 10419 | 35.3 | 9.21 | 10.27 | 5.63 | 22 | 26 | 29 | 33 | 36 | 39 | 42 | 44 | 47 | 0.0696 | 725 | 0.931 | 32.02 | 6.00 | 6 | 0.0509 | 70 | 0.0514 | 0.71 | 3.174 | 0.7185 | 1329.9 | 52792.9 | 2180000 | 92900000 | 0.3888 | 0.2401 | 0.0112 | 0.0000 | 0.0224 | 0.0000 | 0.0384 | 0.0041 | 0.0480 | 0.0132 | 0.0880 | 0.0438 | 0.1296 | 0.0661 | 0.1552 | 0.0867 | 0.2224 | 0.1189 | 0.2848 | 0.6672 | 0.0038 | 0.0000 | 0.0029 | 0.0000 | 0.0105 | 0.0023 | 0.0134 | 0.0077 | 0.0335 | 0.0302 | 0.0374 | 0.0294 | 0.0412 | 0.0394 | 0.0766 | 0.0510 | 0.7807 | 0.8399 | 0.0167 | 0.0854 | 0.0143 | 0.1707 | 0.0263 | 0.1341 | 0.0430 | 0.2073 | 0.0740 | 0.1463 | 0.0883 | 0.2073 | 0.0931 | 0.0244 | 0.1551 | 0.0244 | 0.4893 | 0.0000 | 0.0027 | 0.0040 | 0.0121 | 0.0214 | 0.0429 | 0.0402 | 0.0657 | 0.0979 | 0.7131 | 5 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 15 | 0.2596 | 0.30 | 0.975 | 0.6174 | 137.1 | 3359.17 | 189453 | 16100000 | 0.5305 | 0.1486 | 0.0352 | 0.0019 | 0.0945 | 0.0122 | 0.1668 | 0.0289 | 0.2222 | 0.0571 | 0.2112 | 0.0964 | 0.1536 | 0.1503 | 0.0877 | 0.2161 | 0.0244 | 0.2552 | 0.0044 | 0.1819 | 0.0068 | 0.0000 | 0.0230 | 0.0021 | 0.0437 | 0.0082 | 0.0549 | 0.0212 | 0.0735 | 0.0449 | 0.0787 | 0.0675 | 0.1107 | 0.0939 | 0.1744 | 0.1513 | 0.4343 | 0.6109 | 0.0472 | 0.0923 | 0.0513 | 0.1077 | 0.0808 | 0.1294 | 0.1073 | 0.1464 | 0.1292 | 0.1422 | 0.1429 | 0.1316 | 0.1703 | 0.1167 | 0.1551 | 0.0716 | 0.1158 | 0.0621 | 0.0303 | 0.0432 | 0.0455 | 0.0586 | 0.0760 | 0.1103 | 0.1403 | 0.2192 | 0.2767 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 710 | 620 | | 2360 | 11953 | 110.5 | 24.96 | 211.01 | 181.60 | 79 | 90 | 97 | 103 | 109 | 115 | 122 | 130 | 142 | 0.0590 | 705 | 0.447 | 155.82 | 21.02 | 1 | 0.1462 | 345 | 0.0035 | 13.00 | 5.933 | 0.3106 | 12827.3 | 1560000 | 199000000 | 26300000000 | 0.4832 | 0.1861 | 0.0020 | 0.0000 | 0.0067 | 0.0009 | 0.0153 | 0.0032 | 0.0313 | 0.0074 | 0.0825 | 0.0300 | 0.1297 | 0.0669 | 0.1457 | 0.0646 | 0.1816 | 0.0817 | 0.4052 | 0.7453 | 0.0000 | 0.0000 | 0.0021 | 0.0004 | 0.0046 | 0.0022 | 0.0108 | 0.0043 | 0.0344 | 0.0195 | 0.0729 | 0.0468 | 0.0667 | 0.0299 | 0.0959 | 0.0468 | 0.7127 | 0.8501 | 0.0135 | 0.0000 | 0.0202 | 0.0142 | 0.0314 | 0.0638 | 0.0695 | 0.1702 | 0.1457 | 0.2766 | 0.1570 | 0.2057 | 0.1771 | 0.1135 | 0.1592 | 0.0922 | 0.2265 | 0.0638 | 0.0026 | 0.0026 | 0.0105 | 0.0438 | 0.0771 | 0.1402 | 0.1174 | 0.1446 | 0.4610 | 19 | 35 | 72 | 116 | 165 | 219 | 291 | 373 | 476 | 0.0088 | 40.77 | 6.716 | 0.3192 | 77499.7 | 35900000 | 19100000000 | 11300000000000 | 0.4707 | 0.1858 | 0.0171 | 0.0021 | 0.0769 | 0.0036 | 0.2135 | 0.0261 | 0.1532 | 0.0751 | 0.1780 | 0.1641 | 0.1449 | 0.2033 | 0.1100 | 0.1570 | 0.0651 | 0.1501 | 0.0414 | 0.2187 | 0.0003 | 0.0006 | 0.0014 | 0.0012 | 0.0042 | 0.0020 | 0.0115 | 0.0070 | 0.0431 | 0.0341 | 0.0776 | 0.0678 | 0.0739 | 0.0548 | 0.0927 | 0.0836 | 0.6952 | 0.7490 | 0.0010 | 0.0009 | 0.0021 | 0.0014 | 0.0067 | 0.0080 | 0.0200 | 0.0233 | 0.0562 | 0.0639 | 0.0998 | 0.1198 | 0.0814 | 0.0974 | 0.1131 | 0.1263 | 0.6197 | 0.5591 | 0.0002 | 0.0010 | 0.0051 | 0.0156 | 0.0562 | 0.0902 | 0.0770 | 0.0984 | 0.6564 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 927 | 887 | | 3637 | 16754 | 208.9 | 92.53 | 65.01 | 116.76 | 121 | 135 | 144 | 158 | 179 | 205 | 235 | 270 | 358 | 0.0556 | 932 | 0.834 | 150.33 | 54.74 | 2 | 0.1270 | 462 | 0.0037 | 12.92 | 6.141 | 0.3836 | 52205.7 | 15500000 | 5250000000 | 1970000000000 | 0.4763 | 0.1819 | 0.0019 | 0.0015 | 0.0029 | 0.0023 | 0.0229 | 0.0034 | 0.0381 | 0.0138 | 0.0705 | 0.0356 | 0.0896 | 0.0521 | 0.0925 | 0.0502 | 0.1211 | 0.0705 | 0.5605 | 0.7705 | 0.0010 | 0.0013 | 0.0010 | 0.0016 | 0.0050 | 0.0022 | 0.0076 | 0.0094 | 0.0222 | 0.0216 | 0.0443 | 0.0388 | 0.0267 | 0.0297 | 0.0489 | 0.0503 | 0.8433 | 0.8452 | 0.0021 | 0.0000 | 0.0011 | 0.0068 | 0.0064 | 0.0034 | 0.0139 | 0.0051 | 0.0502 | 0.0425 | 0.0694 | 0.0969 | 0.0491 | 0.0459 | 0.0780 | 0.0986 | 0.7297 | 0.7007 | 0.0014 | 0.0021 | 0.0014 | 0.0057 | 0.0291 | 0.0704 | 0.0455 | 0.0824 | 0.7619 | 5 | 7 | 8 | 10 | 13 | 21 | 44 | 90 | 198 | 0.1255 | 5.70 | 3.389 | 0.6022 | 17857.4 | 7770000 | 4140000000 | 2500000000000 | 0.4976 | 0.1519 | 0.0344 | 0.0046 | 0.1527 | 0.0207 | 0.2796 | 0.0718 | 0.1989 | 0.1314 | 0.1452 | 0.1840 | 0.0882 | 0.2058 | 0.0527 | 0.1436 | 0.0312 | 0.1193 | 0.0172 | 0.1188 | 0.0002 | 0.0009 | 0.0019 | 0.0019 | 0.0043 | 0.0024 | 0.0143 | 0.0145 | 0.0517 | 0.0443 | 0.0853 | 0.0765 | 0.0530 | 0.0575 | 0.0866 | 0.0815 | 0.7027 | 0.7204 | 0.0003 | 0.0012 | 0.0024 | 0.0039 | 0.0053 | 0.0051 | 0.0173 | 0.0170 | 0.0587 | 0.0670 | 0.1025 | 0.1053 | 0.0672 | 0.0804 | 0.1014 | 0.1071 | 0.6449 | 0.6130 | 0.0012 | 0.0022 | 0.0050 | 0.0146 | 0.0566 | 0.0853 | 0.0609 | 0.1035 | 0.6707 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1028 | 672 | | 465 | 2154 | 115.4 | 21.95 | 94.06 | 88.63 | 88 | 97 | 102 | 107 | 113 | 119 | 127 | 135 | 145 | 0.1467 | 316 | 0.423 | 90.70 | 21.40 | 1 | 0.5978 | 278 | 0.0052 | 16.34 | 5.463 | 0.2803 | 13796.9 | 1710000 | 218000000 | 28800000000 | 0.4162 | 0.2196 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0247 | 0.0022 | 0.0556 | 0.0111 | 0.1049 | 0.0509 | 0.1852 | 0.0907 | 0.1420 | 0.0575 | 0.1821 | 0.1062 | 0.3025 | 0.6814 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0022 | 0.0273 | 0.0086 | 0.0695 | 0.0452 | 0.1042 | 0.0839 | 0.0720 | 0.0344 | 0.1117 | 0.0796 | 0.6104 | 0.7462 | 0.0000 | 0.0000 | 0.0380 | 0.1538 | 0.0380 | 0.0000 | 0.1139 | 0.1538 | 0.1519 | 0.3846 | 0.2152 | 0.0000 | 0.1392 | 0.1538 | 0.1139 | 0.1538 | 0.1899 | 0.0000 | 0.0000 | 0.0045 | 0.0179 | 0.0538 | 0.1345 | 0.1211 | 0.1211 | 0.1704 | 0.3767 | 17 | 26 | 35 | 44 | 58 | 78 | 107 | 164 | 229 | 0.0192 | 12.21 | 4.935 | 0.4816 | 16699.0 | 4090000 | 1190000000 | 384000000000 | 0.5433 | 0.1288 | 0.0185 | 0.0036 | 0.1218 | 0.0145 | 0.1808 | 0.0416 | 0.1734 | 0.1139 | 0.2251 | 0.1953 | 0.0959 | 0.1664 | 0.0812 | 0.1356 | 0.0554 | 0.1447 | 0.0480 | 0.1844 | 0.0000 | 0.0000 | 0.0056 | 0.0009 | 0.0090 | 0.0027 | 0.0124 | 0.0192 | 0.0710 | 0.0602 | 0.1150 | 0.0794 | 0.0744 | 0.0776 | 0.1488 | 0.1487 | 0.5637 | 0.6113 | 0.0016 | 0.0000 | 0.0032 | 0.0018 | 0.0065 | 0.0147 | 0.0260 | 0.0313 | 0.0666 | 0.0792 | 0.1380 | 0.1455 | 0.0893 | 0.0958 | 0.1347 | 0.1602 | 0.5341 | 0.4715 | 0.0014 | 0.0082 | 0.0109 | 0.0301 | 0.0657 | 0.1012 | 0.0821 | 0.1477 | 0.5527 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1142 | 857 | | 7401 | 14616 | 171.0 | 66.26 | 71.29 | 133.72 | 97 | 113 | 126 | 141 | 159 | 177 | 198 | 227 | 267 | 0.0757 | 1106 | 0.455 | 200.25 | 41.00 | 7 | 0.0947 | 701 | 0.0014 | 22.02 | 6.984 | 0.2885 | 33621.9 | 7480000 | 1840000000 | 492000000000 | 0.3427 | 0.2805 | 0.0023 | 0.0008 | 0.0023 | 0.0025 | 0.0164 | 0.0059 | 0.0279 | 0.0086 | 0.0707 | 0.0301 | 0.1250 | 0.0604 | 0.1170 | 0.0539 | 0.1514 | 0.0722 | 0.4868 | 0.7658 | 0.0004 | 0.0005 | 0.0013 | 0.0012 | 0.0054 | 0.0022 | 0.0073 | 0.0043 | 0.0207 | 0.0130 | 0.0326 | 0.0254 | 0.0318 | 0.0221 | 0.0443 | 0.0300 | 0.8561 | 0.9014 | 0.0010 | 0.0000 | 0.0030 | 0.0041 | 0.0094 | 0.0058 | 0.0189 | 0.0386 | 0.0506 | 0.0641 | 0.0839 | 0.1191 | 0.0645 | 0.0994 | 0.0948 | 0.1224 | 0.6738 | 0.5464 | 0.0012 | 0.0025 | 0.0065 | 0.0109 | 0.0349 | 0.0477 | 0.0514 | 0.0767 | 0.7681 | 10 | 12 | 14 | 16 | 20 | 33 | 59 | 100 | 185 | 0.1556 | 7.37 | 3.609 | 0.6941 | 22963.2 | 18300000 | 21700000000 | 29800000000000 | 0.5623 | 0.1121 | 0.0192 | 0.0013 | 0.1028 | 0.0217 | 0.1742 | 0.0579 | 0.2030 | 0.0744 | 0.1838 | 0.1431 | 0.1324 | 0.1783 | 0.0941 | 0.1601 | 0.0662 | 0.1353 | 0.0244 | 0.2279 | 0.0000 | 0.0002 | 0.0020 | 0.0025 | 0.0051 | 0.0046 | 0.0151 | 0.0122 | 0.0523 | 0.0408 | 0.0785 | 0.0615 | 0.0621 | 0.0522 | 0.0923 | 0.0762 | 0.6926 | 0.7500 | 0.0006 | 0.0003 | 0.0012 | 0.0037 | 0.0062 | 0.0075 | 0.0211 | 0.0251 | 0.0699 | 0.0728 | 0.1077 | 0.1162 | 0.0759 | 0.0799 | 0.1107 | 0.1118 | 0.6067 | 0.5827 | 0.0003 | 0.0008 | 0.0031 | 0.0230 | 0.0637 | 0.0872 | 0.0730 | 0.0993 | 0.6497 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 897 | 352 | | 491 | 10165 | 31.2 | 10.66 | 5.57 | 2.04 | 21 | 23 | 24 | 26 | 27 | 30 | 34 | 40 | 49 | 0.0858 | 872 | 0.813 | 87.21 | 20.59 | 5 | 0.4073 | 200 | 0.0618 | 0.76 | 3.150 | 0.6872 | 1083.9 | 42132.6 | 1810000 | 83600000 | 0.3481 | 0.2731 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0187 | 0.0025 | 0.0561 | 0.0150 | 0.1168 | 0.0848 | 0.2336 | 0.0798 | 0.1963 | 0.0873 | 0.1869 | 0.1446 | 0.1729 | 0.5860 | 0.0061 | 0.0000 | 0.0061 | 0.0000 | 0.0122 | 0.0021 | 0.0334 | 0.0125 | 0.0608 | 0.0582 | 0.0912 | 0.0353 | 0.0821 | 0.0561 | 0.1003 | 0.0811 | 0.6079 | 0.7547 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0348 | 0.0625 | 0.0609 | 0.0500 | 0.1391 | 0.1625 | 0.0609 | 0.1125 | 0.1043 | 0.0750 | 0.6000 | 0.5375 | 0.0000 | 0.0107 | 0.0000 | 0.0481 | 0.0428 | 0.1070 | 0.0695 | 0.1016 | 0.6203 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0061 | 0.11 | 0.381 | 0.0699 | 35.2 | 247.481 | 1925.98 | 16644.2 | 0.5163 | 0.1494 | 0.0075 | 0.0004 | 0.0317 | 0.0014 | 0.1096 | 0.0083 | 0.1889 | 0.0233 | 0.2557 | 0.0515 | 0.2310 | 0.1180 | 0.1247 | 0.2326 | 0.0447 | 0.3477 | 0.0060 | 0.2168 | 0.0016 | 0.0000 | 0.0075 | 0.0002 | 0.0348 | 0.0045 | 0.0908 | 0.0154 | 0.1571 | 0.0325 | 0.2323 | 0.0692 | 0.2275 | 0.1499 | 0.1597 | 0.3269 | 0.0887 | 0.4014 | 0.2469 | 0.4372 | 0.2984 | 0.2271 | 0.1850 | 0.0804 | 0.0888 | 0.0635 | 0.0564 | 0.0536 | 0.0355 | 0.0409 | 0.0392 | 0.0381 | 0.0282 | 0.0381 | 0.0214 | 0.0212 | 0.0197 | 0.0760 | 0.1532 | 0.2101 | 0.1844 | 0.1602 | 0.1001 | 0.0600 | 0.0363 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 208 | 697 | | 4527 | 6306 | 102.3 | 37.27 | 112.28 | 143.75 | 55 | 71 | 81 | 90 | 99 | 108 | 118 | 131 | 151 | 0.0815 | 514 | 0.356 | 141.55 | 33.02 | 1 | 0.1199 | 543 | 0.0021 | 18.08 | 6.438 | 0.2850 | 11862.3 | 1530000 | 217000000 | 33600000000 | 0.4631 | 0.1918 | 0.0025 | 0.0009 | 0.0066 | 0.0006 | 0.0244 | 0.0036 | 0.0533 | 0.0097 | 0.1102 | 0.0425 | 0.1554 | 0.0857 | 0.1640 | 0.0808 | 0.1971 | 0.1227 | 0.2864 | 0.6534 | 0.0000 | 0.0005 | 0.0003 | 0.0003 | 0.0054 | 0.0021 | 0.0123 | 0.0049 | 0.0377 | 0.0210 | 0.0595 | 0.0395 | 0.0687 | 0.0333 | 0.1013 | 0.0546 | 0.7149 | 0.8438 | 0.0025 | 0.0115 | 0.0025 | 0.0263 | 0.0193 | 0.0197 | 0.0495 | 0.0609 | 0.1050 | 0.1184 | 0.1310 | 0.1760 | 0.1125 | 0.1250 | 0.1453 | 0.1612 | 0.4324 | 0.3010 | 0.0009 | 0.0033 | 0.0127 | 0.0216 | 0.0701 | 0.1040 | 0.0861 | 0.1092 | 0.5920 | 15 | 19 | 25 | 33 | 49 | 75 | 115 | 180 | 306 | 0.0287 | 20.58 | 5.086 | 0.4862 | 33266.2 | 15000000 | 8150000000 | 4970000000000 | 0.6440 | 0.0881 | 0.0377 | 0.0048 | 0.1319 | 0.0168 | 0.1852 | 0.0743 | 0.1397 | 0.1086 | 0.1570 | 0.1829 | 0.1287 | 0.1589 | 0.0958 | 0.1238 | 0.0628 | 0.1286 | 0.0612 | 0.2013 | 0.0013 | 0.0007 | 0.0027 | 0.0015 | 0.0080 | 0.0067 | 0.0212 | 0.0176 | 0.0734 | 0.0639 | 0.1008 | 0.1002 | 0.0787 | 0.0740 | 0.1084 | 0.1073 | 0.6055 | 0.6279 | 0.0018 | 0.0028 | 0.0025 | 0.0035 | 0.0135 | 0.0063 | 0.0308 | 0.0232 | 0.0776 | 0.0752 | 0.1145 | 0.1308 | 0.0844 | 0.0893 | 0.1041 | 0.1069 | 0.5708 | 0.5619 | 0.0016 | 0.0057 | 0.0109 | 0.0274 | 0.0677 | 0.1117 | 0.0858 | 0.1101 | 0.5791 |