High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 171 | 227 | | 13156 | 26560 | 216.3 | 55.08 | 143.33 | 196.83 | 147 | 172 | 189 | 203 | 217 | 231 | 246 | 263 | 286 | 0.0570 | 1514 | 0.695 | 170.21 | 47.54 | 3 | 0.0364 | 479 | 0.0008 | 42.66 | 7.414 | 0.1765 | 49810.3 | 12100000 | 3040000000 | 797000000000 | 0.4175 | 0.2260 | 0.0007 | 0.0001 | 0.0014 | 0.0001 | 0.0076 | 0.0009 | 0.0228 | 0.0052 | 0.0655 | 0.0153 | 0.1188 | 0.0349 | 0.1344 | 0.0418 | 0.1753 | 0.0659 | 0.4735 | 0.8359 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0004 | 0.0075 | 0.0020 | 0.0220 | 0.0098 | 0.0398 | 0.0182 | 0.0480 | 0.0148 | 0.0644 | 0.0241 | 0.8168 | 0.9308 | 0.0028 | 0.0282 | 0.0118 | 0.0267 | 0.0277 | 0.0847 | 0.0602 | 0.1278 | 0.0906 | 0.1798 | 0.1387 | 0.1575 | 0.1280 | 0.1189 | 0.1505 | 0.1218 | 0.3898 | 0.1545 | 0.0012 | 0.0034 | 0.0079 | 0.0230 | 0.0477 | 0.0880 | 0.0938 | 0.1052 | 0.6296 | 16 | 19 | 22 | 26 | 40 | 80 | 154 | 256 | 424 | 0.0499 | 24.57 | 5.020 | 0.5076 | 59283.3 | 35800000 | 26400000000 | 22500000000000 | 0.6077 | 0.0916 | 0.0465 | 0.0024 | 0.1573 | 0.0221 | 0.2370 | 0.0945 | 0.1899 | 0.1299 | 0.1567 | 0.1853 | 0.1107 | 0.1877 | 0.0559 | 0.1296 | 0.0288 | 0.1216 | 0.0172 | 0.1270 | 0.0004 | 0.0003 | 0.0007 | 0.0014 | 0.0025 | 0.0019 | 0.0149 | 0.0139 | 0.0556 | 0.0499 | 0.0753 | 0.0693 | 0.0592 | 0.0511 | 0.0899 | 0.0801 | 0.7015 | 0.7321 | 0.0005 | 0.0015 | 0.0016 | 0.0014 | 0.0046 | 0.0059 | 0.0219 | 0.0234 | 0.0658 | 0.0751 | 0.1028 | 0.1190 | 0.0811 | 0.0870 | 0.1118 | 0.1202 | 0.6099 | 0.5665 | 0.0007 | 0.0013 | 0.0027 | 0.0190 | 0.0556 | 0.0905 | 0.0669 | 0.0992 | 0.6642 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 396 | 484 | | 6705 | 17320 | 296.7 | 54.52 | 188.36 | 215.38 | 229 | 252 | 268 | 281 | 294 | 308 | 323 | 341 | 366 | 0.0651 | 1128 | 1.125 | 100.81 | 34.53 | 1 | 0.0374 | 251 | 0.0007 | 67.59 | 7.448 | 0.1401 | 90991.5 | 28800000 | 9420000000 | 3170000000000 | 0.4266 | 0.2263 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0098 | 0.0006 | 0.0495 | 0.0149 | 0.1217 | 0.0298 | 0.1315 | 0.0281 | 0.1657 | 0.0445 | 0.5202 | 0.8819 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0034 | 0.0005 | 0.0240 | 0.0123 | 0.0580 | 0.0227 | 0.0573 | 0.0162 | 0.0780 | 0.0241 | 0.7791 | 0.9240 | 0.0135 | 0.0226 | 0.0303 | 0.0376 | 0.0359 | 0.1053 | 0.1144 | 0.1805 | 0.1435 | 0.2030 | 0.1973 | 0.1729 | 0.1278 | 0.0977 | 0.1200 | 0.0602 | 0.2175 | 0.1203 | 0.0015 | 0.0031 | 0.0096 | 0.0383 | 0.0887 | 0.1279 | 0.1192 | 0.1440 | 0.4677 | 12 | 16 | 22 | 42 | 95 | 169 | 260 | 362 | 503 | 0.0312 | 34.76 | 5.776 | 0.4635 | 81864.7 | 47300000 | 32600000000 | 25500000000000 | 0.5378 | 0.1169 | 0.0484 | 0.0023 | 0.2080 | 0.0231 | 0.2597 | 0.1353 | 0.1473 | 0.1298 | 0.1053 | 0.1761 | 0.1040 | 0.2018 | 0.0536 | 0.1017 | 0.0523 | 0.0809 | 0.0213 | 0.1490 | 0.0004 | 0.0000 | 0.0012 | 0.0007 | 0.0020 | 0.0011 | 0.0082 | 0.0055 | 0.0496 | 0.0436 | 0.0956 | 0.0812 | 0.0682 | 0.0576 | 0.0952 | 0.0781 | 0.6795 | 0.7322 | 0.0003 | 0.0004 | 0.0026 | 0.0012 | 0.0036 | 0.0043 | 0.0123 | 0.0179 | 0.0625 | 0.0724 | 0.1204 | 0.1323 | 0.0904 | 0.0940 | 0.1169 | 0.1260 | 0.5908 | 0.5516 | 0.0002 | 0.0012 | 0.0024 | 0.0085 | 0.0599 | 0.1074 | 0.0784 | 0.1028 | 0.6392 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 976 | 656 | | 13290 | 29012 | 350.5 | 83.54 | 117.42 | 202.47 | 252 | 284 | 306 | 327 | 348 | 369 | 393 | 419 | 457 | 0.0458 | 1328 | 1.206 | 145.66 | 51.35 | 3 | 0.0266 | 354 | 0.0009 | 33.81 | 7.228 | 0.1932 | 129853.0 | 50400000 | 20400000000 | 8570000000000 | 0.4626 | 0.1869 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0137 | 0.0009 | 0.0626 | 0.0154 | 0.1394 | 0.0357 | 0.1429 | 0.0364 | 0.1618 | 0.0560 | 0.4786 | 0.8556 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0047 | 0.0002 | 0.0239 | 0.0104 | 0.0583 | 0.0216 | 0.0527 | 0.0167 | 0.0693 | 0.0259 | 0.7910 | 0.9253 | 0.0016 | 0.0134 | 0.0070 | 0.0202 | 0.0147 | 0.0353 | 0.0609 | 0.1109 | 0.1230 | 0.1681 | 0.1707 | 0.1983 | 0.1145 | 0.1059 | 0.1486 | 0.1345 | 0.3589 | 0.2134 | 0.0002 | 0.0012 | 0.0066 | 0.0185 | 0.0678 | 0.1107 | 0.0917 | 0.1206 | 0.5827 | 6 | 7 | 9 | 10 | 12 | 24 | 88 | 206 | 406 | 0.1454 | 15.57 | 3.922 | 0.5837 | 54782.0 | 35700000 | 27800000000 | 24300000000000 | 0.5329 | 0.1352 | 0.0637 | 0.0030 | 0.1850 | 0.0394 | 0.2305 | 0.1421 | 0.1607 | 0.1285 | 0.1562 | 0.1739 | 0.0925 | 0.1834 | 0.0652 | 0.1156 | 0.0326 | 0.0940 | 0.0136 | 0.1201 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0018 | 0.0013 | 0.0098 | 0.0088 | 0.0421 | 0.0384 | 0.0678 | 0.0575 | 0.0453 | 0.0456 | 0.0680 | 0.0641 | 0.7645 | 0.7842 | 0.0000 | 0.0003 | 0.0004 | 0.0007 | 0.0017 | 0.0025 | 0.0116 | 0.0124 | 0.0523 | 0.0544 | 0.0850 | 0.0971 | 0.0615 | 0.0646 | 0.0847 | 0.0903 | 0.7028 | 0.6776 | 0.0004 | 0.0005 | 0.0019 | 0.0076 | 0.0494 | 0.0725 | 0.0487 | 0.0795 | 0.7395 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 906 | 300 | | 4616 | 2545 | 127.3 | 33.98 | 169.06 | 144.46 | 93 | 100 | 108 | 114 | 121 | 129 | 137 | 149 | 170 | 0.2303 | 586 | 0.655 | 101.26 | 21.10 | 1 | 0.0570 | 263 | 0.0024 | 23.69 | 6.393 | 0.2429 | 17366.0 | 2560000 | 415000000 | 74600000000 | 0.4222 | 0.2295 | 0.0007 | 0.0000 | 0.0025 | 0.0000 | 0.0079 | 0.0000 | 0.0229 | 0.0026 | 0.0947 | 0.0259 | 0.1804 | 0.0581 | 0.1701 | 0.0504 | 0.1851 | 0.0910 | 0.3358 | 0.7719 | 0.0006 | 0.0000 | 0.0014 | 0.0000 | 0.0030 | 0.0000 | 0.0099 | 0.0013 | 0.0432 | 0.0143 | 0.0842 | 0.0317 | 0.0803 | 0.0229 | 0.1119 | 0.0419 | 0.6656 | 0.8878 | 0.0036 | 0.0107 | 0.0024 | 0.0000 | 0.0358 | 0.0188 | 0.0896 | 0.0965 | 0.1290 | 0.1662 | 0.1673 | 0.2011 | 0.1159 | 0.1421 | 0.1398 | 0.1582 | 0.3166 | 0.2064 | 0.0041 | 0.0041 | 0.0086 | 0.0436 | 0.0933 | 0.1379 | 0.1206 | 0.1409 | 0.4470 | 36 | 55 | 71 | 93 | 121 | 154 | 206 | 274 | 374 | 0.0029 | 65.12 | 6.499 | 0.2709 | 49440.3 | 19800000 | 9460000000 | 5070000000000 | 0.5100 | 0.1410 | 0.0427 | 0.0025 | 0.1467 | 0.0272 | 0.3413 | 0.0938 | 0.1973 | 0.1284 | 0.1040 | 0.2062 | 0.0960 | 0.2185 | 0.0400 | 0.1173 | 0.0240 | 0.1099 | 0.0080 | 0.0963 | 0.0009 | 0.0000 | 0.0061 | 0.0027 | 0.0182 | 0.0089 | 0.0425 | 0.0336 | 0.0981 | 0.0960 | 0.1389 | 0.1289 | 0.1076 | 0.0981 | 0.1250 | 0.1310 | 0.4627 | 0.5007 | 0.0026 | 0.0031 | 0.0064 | 0.0062 | 0.0154 | 0.0278 | 0.0605 | 0.0571 | 0.1107 | 0.1142 | 0.1725 | 0.1821 | 0.1042 | 0.1049 | 0.1184 | 0.1219 | 0.4093 | 0.3827 | 0.0021 | 0.0086 | 0.0182 | 0.0376 | 0.1116 | 0.1642 | 0.0998 | 0.1202 | 0.4378 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1013 | 776 | | 4132 | 4149 | 163.6 | 45.21 | 162.20 | 159.12 | 116 | 127 | 136 | 145 | 155 | 166 | 178 | 197 | 224 | 0.1347 | 559 | 1.127 | 94.07 | 29.83 | 1 | 0.0549 | 227 | 0.0016 | 35.59 | 6.765 | 0.2144 | 28795.0 | 5490000 | 1140000000 | 256000000000 | 0.3736 | 0.2711 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0097 | 0.0000 | 0.0313 | 0.0016 | 0.1031 | 0.0289 | 0.1793 | 0.0586 | 0.1696 | 0.0559 | 0.1608 | 0.0805 | 0.3449 | 0.7744 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0000 | 0.0126 | 0.0012 | 0.0426 | 0.0173 | 0.0765 | 0.0318 | 0.0726 | 0.0202 | 0.0833 | 0.0333 | 0.7089 | 0.8961 | 0.0012 | 0.0057 | 0.0060 | 0.0028 | 0.0193 | 0.0342 | 0.0712 | 0.1026 | 0.1351 | 0.1852 | 0.1689 | 0.1538 | 0.1074 | 0.1254 | 0.1544 | 0.1282 | 0.3366 | 0.2621 | 0.0006 | 0.0029 | 0.0081 | 0.0400 | 0.0737 | 0.1398 | 0.0986 | 0.1119 | 0.5244 | 19 | 39 | 59 | 79 | 105 | 140 | 187 | 267 | 405 | 0.0058 | 51.95 | 6.395 | 0.3274 | 51621.9 | 23000000 | 12200000000 | 7280000000000 | 0.4555 | 0.1933 | 0.0214 | 0.0008 | 0.1246 | 0.0084 | 0.2206 | 0.0489 | 0.1851 | 0.1281 | 0.1495 | 0.1778 | 0.1388 | 0.1912 | 0.0747 | 0.1272 | 0.0534 | 0.1348 | 0.0320 | 0.1828 | 0.0006 | 0.0000 | 0.0011 | 0.0036 | 0.0034 | 0.0027 | 0.0238 | 0.0173 | 0.0747 | 0.0600 | 0.1065 | 0.1055 | 0.0821 | 0.0673 | 0.1121 | 0.1014 | 0.5957 | 0.6421 | 0.0017 | 0.0000 | 0.0033 | 0.0040 | 0.0083 | 0.0049 | 0.0282 | 0.0346 | 0.0698 | 0.0949 | 0.1412 | 0.1215 | 0.0947 | 0.1057 | 0.1204 | 0.1364 | 0.5324 | 0.4980 | 0.0007 | 0.0034 | 0.0103 | 0.0248 | 0.0765 | 0.1254 | 0.0827 | 0.1158 | 0.5603 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 301 | 366 | | 6423 | 26442 | 283.5 | 88.59 | 136.46 | 161.23 | 181 | 203 | 226 | 250 | 273 | 298 | 324 | 354 | 403 | 0.0445 | 1176 | 1.048 | 155.22 | 58.08 | 2 | 0.0629 | 404 | 0.0011 | 32.72 | 7.058 | 0.2184 | 88205.5 | 29900000 | 10900000000 | 4280000000000 | 0.4253 | 0.2195 | 0.0007 | 0.0000 | 0.0034 | 0.0009 | 0.0146 | 0.0032 | 0.0409 | 0.0087 | 0.0940 | 0.0368 | 0.1492 | 0.0716 | 0.1359 | 0.0612 | 0.1683 | 0.0927 | 0.3931 | 0.7248 | 0.0002 | 0.0000 | 0.0009 | 0.0007 | 0.0040 | 0.0017 | 0.0105 | 0.0042 | 0.0296 | 0.0204 | 0.0525 | 0.0362 | 0.0423 | 0.0262 | 0.0710 | 0.0400 | 0.7891 | 0.8707 | 0.0013 | 0.0070 | 0.0064 | 0.0098 | 0.0135 | 0.0209 | 0.0411 | 0.0809 | 0.1046 | 0.1492 | 0.1380 | 0.1618 | 0.1014 | 0.1213 | 0.1444 | 0.1269 | 0.4493 | 0.3222 | 0.0000 | 0.0020 | 0.0040 | 0.0131 | 0.0529 | 0.0827 | 0.0844 | 0.1138 | 0.6471 | 9 | 14 | 24 | 38 | 66 | 107 | 167 | 252 | 373 | 0.0462 | 12.01 | 4.985 | 0.5301 | 44615.1 | 20200000 | 11100000000 | 6860000000000 | 0.4314 | 0.2136 | 0.0461 | 0.0018 | 0.1520 | 0.0172 | 0.2501 | 0.0918 | 0.1590 | 0.1281 | 0.1504 | 0.1891 | 0.1005 | 0.1767 | 0.0606 | 0.1214 | 0.0494 | 0.1181 | 0.0317 | 0.1558 | 0.0002 | 0.0002 | 0.0001 | 0.0004 | 0.0016 | 0.0014 | 0.0128 | 0.0100 | 0.0523 | 0.0437 | 0.0925 | 0.0734 | 0.0653 | 0.0565 | 0.0976 | 0.0819 | 0.6777 | 0.7324 | 0.0001 | 0.0006 | 0.0009 | 0.0013 | 0.0036 | 0.0042 | 0.0155 | 0.0196 | 0.0730 | 0.0822 | 0.1241 | 0.1392 | 0.0858 | 0.0894 | 0.1200 | 0.1337 | 0.5771 | 0.5298 | 0.0001 | 0.0005 | 0.0029 | 0.0149 | 0.0623 | 0.1047 | 0.0750 | 0.1099 | 0.6295 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1018 | 588 | | 3811 | 2194 | 152.8 | 45.25 | 165.29 | 120.38 | 109 | 118 | 126 | 134 | 142 | 151 | 164 | 180 | 214 | 0.2334 | 512 | 1.053 | 95.88 | 21.84 | 1 | 0.0559 | 213 | 0.0019 | 30.81 | 6.595 | 0.2281 | 25408.3 | 4650000 | 946000000 | 214000000000 | 0.3988 | 0.2432 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0000 | 0.0266 | 0.0015 | 0.1000 | 0.0318 | 0.1613 | 0.0588 | 0.1678 | 0.0558 | 0.1730 | 0.0780 | 0.3604 | 0.7742 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0053 | 0.0000 | 0.0145 | 0.0008 | 0.0469 | 0.0184 | 0.0800 | 0.0301 | 0.0793 | 0.0235 | 0.0959 | 0.0379 | 0.6781 | 0.8893 | 0.0014 | 0.0000 | 0.0201 | 0.0000 | 0.0086 | 0.0026 | 0.0459 | 0.0741 | 0.1119 | 0.1481 | 0.1607 | 0.1984 | 0.0947 | 0.1085 | 0.1349 | 0.1614 | 0.4218 | 0.3069 | 0.0040 | 0.0094 | 0.0101 | 0.0330 | 0.0808 | 0.1359 | 0.0969 | 0.1151 | 0.5148 | 45 | 64 | 85 | 108 | 136 | 167 | 200 | 252 | 322 | 0.0021 | 74.42 | 6.577 | 0.2161 | 41805.4 | 14100000 | 5770000000 | 2690000000000 | 0.5152 | 0.1357 | 0.0346 | 0.0000 | 0.1364 | 0.0171 | 0.2165 | 0.0798 | 0.1667 | 0.1277 | 0.1688 | 0.1631 | 0.1190 | 0.1836 | 0.0909 | 0.1072 | 0.0455 | 0.1482 | 0.0216 | 0.1733 | 0.0000 | 0.0000 | 0.0009 | 0.0014 | 0.0097 | 0.0043 | 0.0292 | 0.0264 | 0.1205 | 0.0785 | 0.1763 | 0.1527 | 0.1045 | 0.0935 | 0.1523 | 0.1456 | 0.4066 | 0.4975 | 0.0030 | 0.0057 | 0.0045 | 0.0038 | 0.0285 | 0.0286 | 0.0615 | 0.0782 | 0.1529 | 0.1794 | 0.2144 | 0.2271 | 0.1229 | 0.1355 | 0.1439 | 0.1240 | 0.2684 | 0.2176 | 0.0011 | 0.0034 | 0.0202 | 0.0506 | 0.1406 | 0.1755 | 0.1260 | 0.1586 | 0.3240 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 526 | 612 | | 4592 | 11096 | 714.2 | 99.82 | 91.74 | 166.81 | 589 | 634 | 669 | 693 | 712 | 732 | 756 | 790 | 865 | 0.0617 | 685 | 1.192 | 82.49 | 32.31 | 1 | 0.0464 | 213 | 0.0012 | 39.16 | 7.036 | 0.2240 | 520098.0 | 386000000 | 291000000000 | 223000000000000 | 0.3926 | 0.2577 | 0.0013 | 0.0000 | 0.0016 | 0.0000 | 0.0024 | 0.0000 | 0.0078 | 0.0000 | 0.0202 | 0.0126 | 0.0427 | 0.0244 | 0.0333 | 0.0109 | 0.0462 | 0.0196 | 0.8444 | 0.9324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0000 | 0.0120 | 0.0126 | 0.0271 | 0.0244 | 0.0165 | 0.0109 | 0.0268 | 0.0196 | 0.9153 | 0.9324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0133 | 0.0000 | 0.0285 | 0.0000 | 0.0645 | 0.0000 | 0.1082 | 0.0000 | 0.1176 | 0.0000 | 0.1442 | 0.0000 | 0.5237 | 0.0000 | 0.0022 | 0.0027 | 0.0111 | 0.0200 | 0.0408 | 0.0616 | 0.0585 | 0.0789 | 0.7242 | 7 | 9 | 10 | 13 | 19 | 35 | 59 | 122 | 282 | 0.1396 | 15.62 | 3.866 | 0.6295 | 36238.5 | 22600000 | 17000000000 | 14400000000000 | 0.4303 | 0.1803 | 0.0541 | 0.0062 | 0.1723 | 0.0346 | 0.2804 | 0.0892 | 0.1486 | 0.1277 | 0.1216 | 0.1600 | 0.0912 | 0.1738 | 0.0456 | 0.1138 | 0.0372 | 0.1200 | 0.0490 | 0.1746 | 0.0007 | 0.0006 | 0.0014 | 0.0026 | 0.0061 | 0.0038 | 0.0208 | 0.0191 | 0.0546 | 0.0430 | 0.0869 | 0.0774 | 0.0440 | 0.0543 | 0.0617 | 0.0676 | 0.7238 | 0.7317 | 0.0009 | 0.0009 | 0.0021 | 0.0023 | 0.0081 | 0.0069 | 0.0214 | 0.0236 | 0.0585 | 0.0573 | 0.0880 | 0.0906 | 0.0440 | 0.0495 | 0.0679 | 0.0703 | 0.7091 | 0.6986 | 0.0008 | 0.0015 | 0.0073 | 0.0191 | 0.0546 | 0.0863 | 0.0454 | 0.0569 | 0.7281 | ||
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 937 | 792 | | 9123 | 21746 | 335.0 | 60.34 | 75.58 | 106.02 | 251 | 283 | 304 | 322 | 338 | 352 | 368 | 385 | 407 | 0.0469 | 1020 | 1.203 | 88.96 | 31.32 | 2 | 0.0240 | 219 | 0.0031 | 5.79 | 6.087 | 0.3990 | 115860.0 | 41200000 | 15100000000 | 5640000000000 | 0.3775 | 0.2592 | 0.0006 | 0.0000 | 0.0019 | 0.0001 | 0.0030 | 0.0007 | 0.0099 | 0.0012 | 0.0231 | 0.0099 | 0.0367 | 0.0248 | 0.0410 | 0.0160 | 0.0611 | 0.0234 | 0.8226 | 0.9239 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0010 | 0.0003 | 0.0037 | 0.0008 | 0.0116 | 0.0086 | 0.0156 | 0.0195 | 0.0156 | 0.0089 | 0.0230 | 0.0132 | 0.9290 | 0.9487 | 0.0127 | 0.0397 | 0.0136 | 0.0397 | 0.0363 | 0.1429 | 0.0417 | 0.1190 | 0.0644 | 0.1587 | 0.0816 | 0.1905 | 0.0743 | 0.0635 | 0.0988 | 0.0952 | 0.5766 | 0.1508 | 0.0021 | 0.0040 | 0.0109 | 0.0129 | 0.0253 | 0.0322 | 0.0430 | 0.0670 | 0.8026 | 6 | 7 | 9 | 13 | 26 | 46 | 79 | 134 | 219 | 0.0597 | 7.19 | 4.039 | 0.5263 | 16952.4 | 5760000 | 2510000000 | 1300000000000 | 0.3182 | 0.3239 | 0.0564 | 0.0038 | 0.1472 | 0.0263 | 0.2620 | 0.0928 | 0.1675 | 0.1276 | 0.1368 | 0.1702 | 0.0969 | 0.1688 | 0.0595 | 0.1401 | 0.0485 | 0.1159 | 0.0252 | 0.1545 | 0.0001 | 0.0005 | 0.0012 | 0.0006 | 0.0032 | 0.0031 | 0.0151 | 0.0112 | 0.0474 | 0.0451 | 0.0827 | 0.0582 | 0.0582 | 0.0542 | 0.0838 | 0.0756 | 0.7083 | 0.7517 | 0.0012 | 0.0002 | 0.0012 | 0.0019 | 0.0027 | 0.0043 | 0.0211 | 0.0249 | 0.0642 | 0.0784 | 0.1127 | 0.1071 | 0.0701 | 0.0779 | 0.0991 | 0.1155 | 0.6278 | 0.5898 | 0.0006 | 0.0010 | 0.0024 | 0.0164 | 0.0621 | 0.0942 | 0.0691 | 0.0956 | 0.6587 | ||
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1249 | 769 | | 4803 | 11247 | 502.2 | 83.00 | 67.05 | 122.38 | 382 | 431 | 463 | 488 | 508 | 528 | 552 | 579 | 608 | 0.0648 | 729 | 1.156 | 88.46 | 33.06 | 1 | 0.0477 | 229 | 0.0014 | 23.98 | 6.830 | 0.2358 | 259094.0 | 137000000 | 73800000000 | 40500000000000 | 0.4284 | 0.2133 | 0.0011 | 0.0000 | 0.0019 | 0.0000 | 0.0044 | 0.0000 | 0.0091 | 0.0002 | 0.0299 | 0.0136 | 0.0517 | 0.0206 | 0.0575 | 0.0124 | 0.0811 | 0.0183 | 0.7632 | 0.9350 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0002 | 0.0170 | 0.0136 | 0.0276 | 0.0206 | 0.0218 | 0.0124 | 0.0377 | 0.0183 | 0.8937 | 0.9350 | 0.0072 | 0.0000 | 0.0181 | 0.0000 | 0.0325 | 0.0000 | 0.0597 | 0.0000 | 0.0868 | 0.0000 | 0.1374 | 0.0000 | 0.1230 | 0.0000 | 0.1754 | 0.0000 | 0.3599 | 0.0000 | 0.0019 | 0.0016 | 0.0054 | 0.0140 | 0.0384 | 0.0594 | 0.0602 | 0.0889 | 0.7301 | 6 | 8 | 10 | 12 | 15 | 20 | 38 | 86 | 207 | 0.1665 | 6.51 | 3.350 | 0.6502 | 19470.7 | 8860000 | 4860000000 | 2970000000000 | 0.5816 | 0.0962 | 0.0324 | 0.0043 | 0.1477 | 0.0208 | 0.2216 | 0.0720 | 0.2090 | 0.1276 | 0.1658 | 0.1753 | 0.1189 | 0.1840 | 0.0613 | 0.1372 | 0.0216 | 0.1345 | 0.0216 | 0.1441 | 0.0007 | 0.0003 | 0.0010 | 0.0009 | 0.0034 | 0.0039 | 0.0172 | 0.0128 | 0.0540 | 0.0538 | 0.0890 | 0.0805 | 0.0639 | 0.0589 | 0.0907 | 0.0838 | 0.6801 | 0.7050 | 0.0000 | 0.0005 | 0.0013 | 0.0019 | 0.0030 | 0.0033 | 0.0166 | 0.0196 | 0.0675 | 0.0650 | 0.0968 | 0.1182 | 0.0739 | 0.0715 | 0.0994 | 0.1005 | 0.6416 | 0.6196 | 0.0004 | 0.0015 | 0.0034 | 0.0145 | 0.0574 | 0.1015 | 0.0624 | 0.0915 | 0.6673 | ||
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1189 | 733 | | 6368 | 8540 | 460.5 | 95.33 | 276.86 | 365.75 | 341 | 370 | 398 | 426 | 449 | 474 | 509 | 550 | 597 | 0.0848 | 724 | 0.776 | 177.72 | 41.62 | 1 | 0.0785 | 500 | 0.0009 | 23.98 | 7.222 | 0.2306 | 221183.0 | 111000000 | 57400000000 | 30900000000000 | 0.4039 | 0.2350 | 0.0005 | 0.0000 | 0.0020 | 0.0003 | 0.0059 | 0.0005 | 0.0136 | 0.0018 | 0.0358 | 0.0143 | 0.0491 | 0.0278 | 0.0573 | 0.0203 | 0.0893 | 0.0345 | 0.7465 | 0.9005 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0021 | 0.0000 | 0.0072 | 0.0005 | 0.0145 | 0.0099 | 0.0191 | 0.0206 | 0.0217 | 0.0093 | 0.0320 | 0.0179 | 0.9023 | 0.9419 | 0.0074 | 0.0186 | 0.0017 | 0.0372 | 0.0124 | 0.0558 | 0.0314 | 0.0884 | 0.0553 | 0.1023 | 0.0677 | 0.1395 | 0.0619 | 0.1302 | 0.0958 | 0.1535 | 0.6664 | 0.2744 | 0.0003 | 0.0024 | 0.0069 | 0.0180 | 0.0340 | 0.0506 | 0.0544 | 0.0634 | 0.7698 | 9 | 12 | 16 | 59 | 118 | 196 | 330 | 523 | 797 | 0.0654 | 101.98 | 5.746 | 0.4428 | 210404.0 | 226000000 | 301000000000 | 467000000000000 | 0.4431 | 0.2080 | 0.0250 | 0.0028 | 0.1591 | 0.0106 | 0.2872 | 0.0700 | 0.1944 | 0.1272 | 0.1399 | 0.1965 | 0.1046 | 0.2367 | 0.0442 | 0.1357 | 0.0339 | 0.1074 | 0.0118 | 0.1131 | 0.0000 | 0.0000 | 0.0006 | 0.0011 | 0.0028 | 0.0030 | 0.0130 | 0.0116 | 0.0551 | 0.0462 | 0.0740 | 0.0648 | 0.0688 | 0.0562 | 0.0988 | 0.0759 | 0.6869 | 0.7413 | 0.0008 | 0.0004 | 0.0016 | 0.0026 | 0.0035 | 0.0044 | 0.0208 | 0.0219 | 0.0631 | 0.0804 | 0.1145 | 0.1307 | 0.0922 | 0.0979 | 0.1196 | 0.1281 | 0.5839 | 0.5337 | 0.0000 | 0.0011 | 0.0032 | 0.0151 | 0.0601 | 0.0984 | 0.0766 | 0.1131 | 0.6325 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 320 | 667 | | 5012 | 4003 | 144.6 | 31.00 | 256.96 | 210.61 | 110 | 119 | 126 | 133 | 139 | 146 | 155 | 168 | 187 | 0.1699 | 680 | 1.061 | 130.67 | 36.72 | 1 | 0.0599 | 300 | 0.0023 | 22.41 | 6.404 | 0.2450 | 21873.6 | 3470000 | 577000000 | 101000000000 | 0.4357 | 0.2084 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0059 | 0.0000 | 0.0223 | 0.0013 | 0.0711 | 0.0189 | 0.1355 | 0.0456 | 0.1443 | 0.0439 | 0.1875 | 0.0634 | 0.4320 | 0.8269 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0000 | 0.0083 | 0.0004 | 0.0355 | 0.0130 | 0.0649 | 0.0252 | 0.0675 | 0.0144 | 0.0966 | 0.0244 | 0.7237 | 0.9225 | 0.0073 | 0.0036 | 0.0158 | 0.0144 | 0.0280 | 0.0758 | 0.0767 | 0.1516 | 0.1571 | 0.1913 | 0.1705 | 0.1733 | 0.1255 | 0.1264 | 0.1437 | 0.1155 | 0.2753 | 0.1480 | 0.0038 | 0.0080 | 0.0127 | 0.0363 | 0.0930 | 0.1303 | 0.1085 | 0.1567 | 0.4507 | 33 | 63 | 100 | 155 | 208 | 265 | 333 | 424 | 568 | 0.0020 | 118.54 | 7.148 | 0.2176 | 110371.0 | 60900000 | 39200000000 | 28100000000000 | 0.4840 | 0.1833 | 0.0323 | 0.0038 | 0.1232 | 0.0212 | 0.2097 | 0.0613 | 0.2097 | 0.1272 | 0.1730 | 0.1779 | 0.1510 | 0.2059 | 0.0587 | 0.1476 | 0.0293 | 0.1272 | 0.0132 | 0.1279 | 0.0005 | 0.0000 | 0.0055 | 0.0033 | 0.0099 | 0.0087 | 0.0307 | 0.0229 | 0.0823 | 0.0715 | 0.1368 | 0.1227 | 0.1011 | 0.0932 | 0.1293 | 0.1165 | 0.5040 | 0.5611 | 0.0007 | 0.0055 | 0.0045 | 0.0028 | 0.0112 | 0.0148 | 0.0389 | 0.0572 | 0.1243 | 0.1210 | 0.1534 | 0.1681 | 0.1213 | 0.1385 | 0.1445 | 0.1376 | 0.4012 | 0.3546 | 0.0030 | 0.0066 | 0.0156 | 0.0361 | 0.0968 | 0.1437 | 0.1203 | 0.1371 | 0.4408 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1104 | 606 | | 7792 | 17317 | 455.1 | 84.64 | 91.04 | 159.85 | 350 | 380 | 405 | 428 | 449 | 472 | 497 | 528 | 568 | 0.0587 | 1017 | 0.843 | 136.49 | 39.96 | 1 | 0.0508 | 396 | 0.0009 | 41.02 | 7.256 | 0.1774 | 214248.0 | 104000000 | 52400000000 | 27200000000000 | 0.4390 | 0.2040 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0136 | 0.0005 | 0.0498 | 0.0107 | 0.1097 | 0.0237 | 0.1108 | 0.0193 | 0.1486 | 0.0344 | 0.5627 | 0.9113 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0024 | 0.0000 | 0.0058 | 0.0004 | 0.0229 | 0.0095 | 0.0478 | 0.0189 | 0.0484 | 0.0112 | 0.0635 | 0.0227 | 0.8089 | 0.9373 | 0.0050 | 0.0153 | 0.0059 | 0.0153 | 0.0243 | 0.0458 | 0.0703 | 0.1756 | 0.1456 | 0.1221 | 0.1816 | 0.1603 | 0.1364 | 0.0916 | 0.1356 | 0.1069 | 0.2954 | 0.2672 | 0.0019 | 0.0038 | 0.0059 | 0.0261 | 0.0676 | 0.1051 | 0.0997 | 0.1070 | 0.5829 | 5 | 6 | 7 | 9 | 11 | 25 | 76 | 148 | 295 | 0.1599 | 22.17 | 4.036 | 0.5973 | 33837.1 | 18800000 | 12800000000 | 9900000000000 | 0.6360 | 0.0673 | 0.0357 | 0.0021 | 0.1417 | 0.0167 | 0.2200 | 0.0889 | 0.1536 | 0.1271 | 0.1497 | 0.1836 | 0.1249 | 0.1857 | 0.0694 | 0.1130 | 0.0565 | 0.1130 | 0.0486 | 0.1700 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0006 | 0.0003 | 0.0113 | 0.0062 | 0.0430 | 0.0382 | 0.0708 | 0.0689 | 0.0549 | 0.0430 | 0.0815 | 0.0753 | 0.7371 | 0.7679 | 0.0002 | 0.0000 | 0.0005 | 0.0010 | 0.0049 | 0.0052 | 0.0117 | 0.0160 | 0.0608 | 0.0640 | 0.0963 | 0.1006 | 0.0629 | 0.0694 | 0.0974 | 0.1091 | 0.6653 | 0.6349 | 0.0002 | 0.0006 | 0.0023 | 0.0121 | 0.0489 | 0.0886 | 0.0606 | 0.0917 | 0.6949 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 425 | 828 | | 9686 | 14128 | 100.3 | 24.59 | 205.89 | 202.72 | 72 | 79 | 85 | 91 | 97 | 103 | 110 | 120 | 135 | 0.0773 | 1092 | 0.773 | 63.03 | 19.85 | 4 | 0.0184 | 178 | 0.0016 | 27.28 | 6.760 | 0.2225 | 10667.4 | 1200000 | 143000000 | 18000000000 | 0.4311 | 0.2206 | 0.0007 | 0.0000 | 0.0025 | 0.0002 | 0.0089 | 0.0003 | 0.0289 | 0.0048 | 0.0826 | 0.0210 | 0.1495 | 0.0494 | 0.1653 | 0.0539 | 0.1882 | 0.0764 | 0.3734 | 0.7940 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0043 | 0.0000 | 0.0130 | 0.0021 | 0.0319 | 0.0109 | 0.0542 | 0.0231 | 0.0628 | 0.0163 | 0.0885 | 0.0251 | 0.7438 | 0.9226 | 0.0040 | 0.0078 | 0.0106 | 0.0142 | 0.0227 | 0.0492 | 0.0721 | 0.1410 | 0.1245 | 0.1643 | 0.1668 | 0.2018 | 0.1285 | 0.1294 | 0.1346 | 0.1345 | 0.3362 | 0.1578 | 0.0028 | 0.0044 | 0.0131 | 0.0331 | 0.0776 | 0.1130 | 0.1075 | 0.1367 | 0.5119 | 19 | 33 | 57 | 89 | 132 | 192 | 271 | 367 | 509 | 0.0106 | 35.88 | 6.248 | 0.3841 | 83484.1 | 45100000 | 28900000000 | 21200000000000 | 0.5547 | 0.1227 | 0.0456 | 0.0027 | 0.1805 | 0.0154 | 0.2495 | 0.1234 | 0.1651 | 0.1270 | 0.1294 | 0.1710 | 0.1041 | 0.1743 | 0.0548 | 0.1294 | 0.0370 | 0.1093 | 0.0339 | 0.1475 | 0.0005 | 0.0004 | 0.0013 | 0.0010 | 0.0037 | 0.0030 | 0.0122 | 0.0118 | 0.0659 | 0.0511 | 0.1064 | 0.0942 | 0.0799 | 0.0639 | 0.1109 | 0.0947 | 0.6192 | 0.6799 | 0.0004 | 0.0013 | 0.0022 | 0.0030 | 0.0061 | 0.0106 | 0.0230 | 0.0300 | 0.0848 | 0.0881 | 0.1339 | 0.1427 | 0.0916 | 0.1017 | 0.1258 | 0.1334 | 0.5322 | 0.4892 | 0.0002 | 0.0030 | 0.0037 | 0.0199 | 0.0732 | 0.1163 | 0.0904 | 0.1209 | 0.5723 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 960 | 785 | | 14324 | 30146 | 220.1 | 48.30 | 124.97 | 184.42 | 157 | 180 | 197 | 210 | 222 | 234 | 246 | 262 | 280 | 0.0506 | 1525 | 1.218 | 105.55 | 39.82 | 5 | 0.0186 | 266 | 0.0010 | 36.62 | 7.236 | 0.1928 | 50767.5 | 12200000 | 3020000000 | 771000000000 | 0.3776 | 0.2614 | 0.0006 | 0.0000 | 0.0007 | 0.0000 | 0.0054 | 0.0001 | 0.0194 | 0.0010 | 0.0554 | 0.0114 | 0.1099 | 0.0262 | 0.1289 | 0.0281 | 0.1632 | 0.0425 | 0.5166 | 0.8907 | 0.0003 | 0.0000 | 0.0001 | 0.0000 | 0.0019 | 0.0000 | 0.0064 | 0.0003 | 0.0181 | 0.0084 | 0.0357 | 0.0167 | 0.0450 | 0.0127 | 0.0607 | 0.0189 | 0.8318 | 0.9430 | 0.0040 | 0.0182 | 0.0081 | 0.0286 | 0.0316 | 0.0909 | 0.0683 | 0.1506 | 0.1278 | 0.2052 | 0.1725 | 0.1740 | 0.1366 | 0.1117 | 0.1490 | 0.1039 | 0.3021 | 0.1169 | 0.0009 | 0.0031 | 0.0069 | 0.0208 | 0.0550 | 0.0930 | 0.1034 | 0.1315 | 0.5854 | 12 | 15 | 19 | 26 | 43 | 72 | 121 | 198 | 355 | 0.0673 | 18.66 | 4.787 | 0.5693 | 49625.5 | 32400000 | 28000000000 | 29100000000000 | 0.5089 | 0.1429 | 0.0634 | 0.0024 | 0.1947 | 0.0244 | 0.2245 | 0.1272 | 0.1694 | 0.1268 | 0.1346 | 0.1704 | 0.0969 | 0.1796 | 0.0580 | 0.1221 | 0.0414 | 0.1040 | 0.0170 | 0.1433 | 0.0006 | 0.0003 | 0.0017 | 0.0012 | 0.0033 | 0.0024 | 0.0152 | 0.0164 | 0.0709 | 0.0583 | 0.1015 | 0.0909 | 0.0701 | 0.0625 | 0.1026 | 0.0863 | 0.6341 | 0.6818 | 0.0001 | 0.0007 | 0.0023 | 0.0034 | 0.0068 | 0.0081 | 0.0275 | 0.0324 | 0.0863 | 0.0889 | 0.1257 | 0.1296 | 0.0840 | 0.0940 | 0.1076 | 0.1098 | 0.5596 | 0.5331 | 0.0005 | 0.0014 | 0.0043 | 0.0212 | 0.0766 | 0.1127 | 0.0825 | 0.1069 | 0.5940 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 900 | 171 | | 3930 | 11298 | 497.7 | 103.96 | 94.40 | 173.19 | 316 | 409 | 476 | 500 | 521 | 540 | 560 | 583 | 613 | 0.0641 | 724 | 0.847 | 112.54 | 33.02 | 4 | 0.0832 | 327 | 0.0011 | 32.58 | 7.096 | 0.2211 | 258499.0 | 139000000 | 76000000000 | 42400000000000 | 0.3874 | 0.2511 | 0.0008 | 0.0003 | 0.0015 | 0.0000 | 0.0057 | 0.0000 | 0.0069 | 0.0008 | 0.0413 | 0.0186 | 0.0462 | 0.0251 | 0.0569 | 0.0178 | 0.0810 | 0.0276 | 0.7597 | 0.9099 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0197 | 0.0186 | 0.0188 | 0.0251 | 0.0172 | 0.0178 | 0.0260 | 0.0276 | 0.9179 | 0.9099 | 0.0052 | 0.0000 | 0.0140 | 0.0000 | 0.0315 | 0.0000 | 0.0542 | 0.0000 | 0.0717 | 0.0000 | 0.0944 | 0.0000 | 0.1119 | 0.0000 | 0.1556 | 0.0000 | 0.4615 | 0.0000 | 0.0012 | 0.0042 | 0.0037 | 0.0108 | 0.0279 | 0.0396 | 0.0500 | 0.0629 | 0.7997 | 6 | 7 | 9 | 10 | 14 | 24 | 52 | 125 | 339 | 0.1266 | 21.37 | 4.235 | 0.6154 | 38902.8 | 22700000 | 15400000000 | 11500000000000 | 0.5106 | 0.1373 | 0.0416 | 0.0018 | 0.1323 | 0.0210 | 0.2420 | 0.0602 | 0.1739 | 0.1267 | 0.1815 | 0.2124 | 0.1361 | 0.2042 | 0.0586 | 0.1258 | 0.0265 | 0.1167 | 0.0076 | 0.1313 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0031 | 0.0015 | 0.0097 | 0.0106 | 0.0497 | 0.0439 | 0.0660 | 0.0569 | 0.0453 | 0.0375 | 0.0729 | 0.0623 | 0.7530 | 0.7860 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0013 | 0.0018 | 0.0139 | 0.0172 | 0.0499 | 0.0548 | 0.0820 | 0.0743 | 0.0465 | 0.0535 | 0.0714 | 0.0729 | 0.7342 | 0.7254 | 0.0008 | 0.0000 | 0.0015 | 0.0131 | 0.0528 | 0.0670 | 0.0466 | 0.0751 | 0.7432 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1041 | 916 | | 403 | 1181 | 80.5 | 10.16 | 173.50 | 253.63 | 67 | 70 | 74 | 77 | 80 | 84 | 86 | 90 | 94 | 0.2320 | 274 | 1.030 | 30.08 | 8.00 | 0 | 0.1762 | 71 | 0.1226 | 0.50 | 2.391 | 0.7876 | 6578.3 | 546175 | 46000000 | 3940000000 | 0.3807 | 0.2394 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0188 | 0.0124 | 0.0591 | 0.0422 | 0.1237 | 0.1166 | 0.1022 | 0.0422 | 0.1532 | 0.0794 | 0.5376 | 0.7072 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0176 | 0.0124 | 0.0403 | 0.0422 | 0.1159 | 0.1166 | 0.0554 | 0.0422 | 0.0781 | 0.0794 | 0.6902 | 0.7072 | 0.0800 | 0.0000 | 0.0800 | 0.0000 | 0.0000 | 0.0000 | 0.2000 | 0.0000 | 0.1200 | 0.0000 | 0.0800 | 0.0000 | 0.2000 | 0.0000 | 0.2000 | 0.0000 | 0.0400 | 0.0000 | 0.0048 | 0.0000 | 0.0144 | 0.0383 | 0.1005 | 0.1340 | 0.0861 | 0.1627 | 0.4593 | 19 | 27 | 36 | 48 | 66 | 100 | 161 | 254 | 474 | 0.0380 | 54.53 | 4.632 | 0.4971 | 94375.3 | 84600000 | 95200000000 | 121000000000000 | 0.4414 | 0.1907 | 0.1038 | 0.0045 | 0.2264 | 0.0588 | 0.2170 | 0.1810 | 0.0472 | 0.1267 | 0.1415 | 0.2262 | 0.1321 | 0.1765 | 0.0943 | 0.0679 | 0.0189 | 0.0498 | 0.0189 | 0.1086 | 0.0000 | 0.0000 | 0.0026 | 0.0021 | 0.0026 | 0.0043 | 0.0490 | 0.0322 | 0.1108 | 0.1052 | 0.2010 | 0.1824 | 0.1031 | 0.0966 | 0.1237 | 0.1223 | 0.4072 | 0.4549 | 0.0035 | 0.0041 | 0.0142 | 0.0122 | 0.0284 | 0.0245 | 0.0674 | 0.0531 | 0.1418 | 0.1633 | 0.1596 | 0.1633 | 0.0887 | 0.0939 | 0.1348 | 0.1347 | 0.3617 | 0.3510 | 0.0030 | 0.0030 | 0.0119 | 0.0625 | 0.1310 | 0.1964 | 0.0923 | 0.1190 | 0.3810 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 79 | 365 | | 355 | 368 | 98.5 | 34.30 | 743.33 | 441.89 | 53 | 66 | 81 | 90 | 95 | 105 | 117 | 132 | 143 | 0.3995 | 147 | 1.183 | 36.12 | 15.52 | 1 | 0.2817 | 100 | 0.0040 | 43.26 | 5.614 | 0.2000 | 10879.1 | 1310000 | 169000000 | 22900000000 | 0.3710 | 0.2410 | 0.0000 | 0.0000 | 0.0265 | 0.0000 | 0.1060 | 0.0041 | 0.0927 | 0.0122 | 0.1258 | 0.1306 | 0.2053 | 0.1796 | 0.1589 | 0.1469 | 0.1126 | 0.1429 | 0.1722 | 0.3837 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0159 | 0.0067 | 0.0556 | 0.0669 | 0.1032 | 0.0635 | 0.0635 | 0.0535 | 0.1111 | 0.0702 | 0.6468 | 0.7391 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0297 | 0.1111 | 0.0792 | 0.2037 | 0.1386 | 0.2037 | 0.2673 | 0.2037 | 0.1287 | 0.1296 | 0.1287 | 0.1111 | 0.2277 | 0.0370 | 0.0000 | 0.0060 | 0.0060 | 0.0539 | 0.1257 | 0.1796 | 0.0958 | 0.1796 | 0.3533 | 167 | 338 | 432 | 575 | 717 | 837 | 975 | 1120 | 1332 | 0.0029 | 177.01 | 5.867 | 0.1008 | 747281.0 | 884000000 | 1170000000000 | 1.66E+15 | 0.3788 | 0.2356 | 0.0116 | 0.0127 | 0.1744 | 0.0570 | 0.2209 | 0.0633 | 0.2326 | 0.1266 | 0.1512 | 0.2089 | 0.1279 | 0.1835 | 0.0814 | 0.1835 | 0.0000 | 0.0886 | 0.0000 | 0.0759 | 0.0000 | 0.0040 | 0.0230 | 0.0199 | 0.0230 | 0.0199 | 0.0829 | 0.0598 | 0.1429 | 0.1474 | 0.1060 | 0.1235 | 0.1567 | 0.1474 | 0.1751 | 0.1633 | 0.2903 | 0.3147 | 0.0000 | 0.0000 | 0.0076 | 0.0108 | 0.0458 | 0.0323 | 0.0458 | 0.0860 | 0.2061 | 0.2688 | 0.1756 | 0.2151 | 0.1374 | 0.1720 | 0.2443 | 0.1828 | 0.1374 | 0.0323 | 0.0058 | 0.0173 | 0.0405 | 0.0578 | 0.1214 | 0.1445 | 0.1792 | 0.1850 | 0.2486 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 559 | 397 | | 4059 | 4987 | 157.3 | 43.64 | 166.74 | 137.41 | 113 | 123 | 131 | 139 | 148 | 157 | 168 | 187 | 216 | 0.1313 | 655 | 1.114 | 90.61 | 28.23 | 1 | 0.0532 | 216 | 0.0019 | 30.80 | 6.626 | 0.2263 | 26652.8 | 4910000 | 989000000 | 219000000000 | 0.4120 | 0.2290 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0082 | 0.0005 | 0.0341 | 0.0027 | 0.0928 | 0.0269 | 0.1428 | 0.0626 | 0.1670 | 0.0541 | 0.1833 | 0.0802 | 0.3697 | 0.7729 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0039 | 0.0002 | 0.0135 | 0.0015 | 0.0410 | 0.0154 | 0.0693 | 0.0336 | 0.0738 | 0.0197 | 0.1013 | 0.0351 | 0.6956 | 0.8945 | 0.0051 | 0.0053 | 0.0064 | 0.0132 | 0.0128 | 0.0079 | 0.0370 | 0.1164 | 0.1392 | 0.1138 | 0.1520 | 0.2063 | 0.1137 | 0.1190 | 0.1494 | 0.1349 | 0.3844 | 0.2831 | 0.0006 | 0.0043 | 0.0188 | 0.0389 | 0.0832 | 0.1269 | 0.1014 | 0.1263 | 0.4997 | 31 | 49 | 69 | 94 | 126 | 164 | 210 | 272 | 369 | 0.0031 | 48.39 | 6.631 | 0.2926 | 46678.1 | 17300000 | 7530000000 | 3680000000000 | 0.5082 | 0.1638 | 0.0343 | 0.0038 | 0.1220 | 0.0131 | 0.1792 | 0.0451 | 0.1868 | 0.1264 | 0.1753 | 0.1496 | 0.1334 | 0.2034 | 0.0940 | 0.1508 | 0.0445 | 0.1189 | 0.0305 | 0.1890 | 0.0004 | 0.0007 | 0.0034 | 0.0014 | 0.0038 | 0.0031 | 0.0290 | 0.0239 | 0.0720 | 0.0560 | 0.1195 | 0.1000 | 0.0909 | 0.0796 | 0.1136 | 0.1058 | 0.5673 | 0.6295 | 0.0025 | 0.0023 | 0.0019 | 0.0023 | 0.0120 | 0.0232 | 0.0340 | 0.0518 | 0.1051 | 0.1044 | 0.1385 | 0.1353 | 0.0906 | 0.1067 | 0.1284 | 0.1276 | 0.4871 | 0.4462 | 0.0000 | 0.0061 | 0.0096 | 0.0289 | 0.0851 | 0.1327 | 0.0917 | 0.1155 | 0.5304 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1208 | 205 | | 6928 | 22071 | 341.7 | 78.65 | 108.42 | 121.55 | 242 | 273 | 297 | 318 | 338 | 358 | 381 | 406 | 444 | 0.0464 | 1025 | 0.821 | 127.02 | 32.56 | 1 | 0.0485 | 336 | 0.0010 | 44.29 | 7.174 | 0.1864 | 122938.0 | 46400000 | 18300000000 | 7530000000000 | 0.4442 | 0.2150 | 0.0005 | 0.0000 | 0.0009 | 0.0002 | 0.0054 | 0.0000 | 0.0289 | 0.0006 | 0.0774 | 0.0196 | 0.1548 | 0.0468 | 0.1496 | 0.0486 | 0.1733 | 0.0699 | 0.4092 | 0.8144 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0007 | 0.0000 | 0.0054 | 0.0001 | 0.0331 | 0.0134 | 0.0668 | 0.0319 | 0.0580 | 0.0246 | 0.0875 | 0.0358 | 0.7479 | 0.8940 | 0.0023 | 0.0124 | 0.0062 | 0.0155 | 0.0247 | 0.0310 | 0.0918 | 0.1455 | 0.1550 | 0.2012 | 0.1958 | 0.1827 | 0.1210 | 0.1022 | 0.1365 | 0.1269 | 0.2668 | 0.1827 | 0.0003 | 0.0015 | 0.0063 | 0.0271 | 0.0855 | 0.1353 | 0.1139 | 0.1317 | 0.4984 | 9 | 13 | 22 | 40 | 63 | 94 | 133 | 188 | 275 | 0.0306 | 13.52 | 5.344 | 0.4677 | 26526.8 | 9310000 | 4040000000 | 2020000000000 | 0.4133 | 0.2398 | 0.0339 | 0.0012 | 0.1396 | 0.0060 | 0.2401 | 0.0523 | 0.1953 | 0.1264 | 0.1400 | 0.1867 | 0.1291 | 0.2003 | 0.0747 | 0.1544 | 0.0331 | 0.1250 | 0.0141 | 0.1478 | 0.0006 | 0.0003 | 0.0014 | 0.0015 | 0.0028 | 0.0033 | 0.0161 | 0.0120 | 0.0537 | 0.0500 | 0.0941 | 0.0727 | 0.0729 | 0.0606 | 0.1043 | 0.0889 | 0.6540 | 0.7107 | 0.0007 | 0.0010 | 0.0031 | 0.0019 | 0.0047 | 0.0087 | 0.0232 | 0.0267 | 0.0849 | 0.0952 | 0.1181 | 0.1316 | 0.0860 | 0.0864 | 0.1223 | 0.1332 | 0.5570 | 0.5153 | 0.0002 | 0.0019 | 0.0039 | 0.0193 | 0.0666 | 0.1098 | 0.0796 | 0.1117 | 0.6070 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1246 | 581 | | 5724 | 10893 | 64.5 | 15.39 | 236.73 | 211.09 | 47 | 52 | 56 | 60 | 63 | 66 | 70 | 75 | 83 | 0.1007 | 1097 | 0.634 | 184.57 | 34.06 | 2 | 0.0786 | 450 | 0.0087 | 5.31 | 5.104 | 0.4181 | 4403.3 | 318930 | 24700000 | 2070000000 | 0.5293 | 0.1575 | 0.0011 | 0.0000 | 0.0029 | 0.0002 | 0.0149 | 0.0025 | 0.0344 | 0.0079 | 0.0831 | 0.0249 | 0.1403 | 0.0624 | 0.1470 | 0.0543 | 0.2027 | 0.0933 | 0.3736 | 0.7545 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0073 | 0.0014 | 0.0168 | 0.0048 | 0.0432 | 0.0173 | 0.0852 | 0.0464 | 0.0787 | 0.0324 | 0.1224 | 0.0582 | 0.6454 | 0.8396 | 0.0146 | 0.0251 | 0.0258 | 0.0282 | 0.0538 | 0.0219 | 0.0806 | 0.1066 | 0.1333 | 0.1818 | 0.1445 | 0.1630 | 0.1333 | 0.1348 | 0.1344 | 0.1285 | 0.2800 | 0.2100 | 0.0049 | 0.0125 | 0.0245 | 0.0623 | 0.1061 | 0.1303 | 0.1318 | 0.1477 | 0.3799 | 16 | 25 | 64 | 130 | 196 | 261 | 329 | 412 | 529 | 0.0116 | 86.41 | 6.934 | 0.2713 | 100595.0 | 54000000 | 33700000000 | 23600000000000 | 0.4576 | 0.1893 | 0.0320 | 0.0013 | 0.1436 | 0.0119 | 0.2339 | 0.0569 | 0.1831 | 0.1264 | 0.1737 | 0.1747 | 0.1260 | 0.2062 | 0.0652 | 0.1467 | 0.0332 | 0.1364 | 0.0094 | 0.1396 | 0.0005 | 0.0003 | 0.0027 | 0.0008 | 0.0034 | 0.0019 | 0.0151 | 0.0095 | 0.0589 | 0.0467 | 0.0943 | 0.0811 | 0.0861 | 0.0713 | 0.1289 | 0.1061 | 0.6100 | 0.6824 | 0.0003 | 0.0012 | 0.0025 | 0.0031 | 0.0076 | 0.0127 | 0.0227 | 0.0347 | 0.0882 | 0.1018 | 0.1372 | 0.1535 | 0.1175 | 0.1148 | 0.1447 | 0.1528 | 0.4794 | 0.4254 | 0.0017 | 0.0015 | 0.0040 | 0.0185 | 0.0733 | 0.1092 | 0.0968 | 0.1432 | 0.5521 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1098 | 245 | | 11985 | 25048 | 84.9 | 24.68 | 210.46 | 174.39 | 57 | 66 | 72 | 78 | 83 | 89 | 96 | 104 | 117 | 0.0493 | 1235 | 1.212 | 170.77 | 60.46 | 3 | 0.0339 | 406 | 0.0035 | 11.99 | 6.022 | 0.3238 | 7822.1 | 773291 | 81600000 | 9180000000 | 0.4646 | 0.2016 | 0.0015 | 0.0001 | 0.0035 | 0.0002 | 0.0189 | 0.0013 | 0.0497 | 0.0060 | 0.0986 | 0.0268 | 0.1577 | 0.0599 | 0.1701 | 0.0693 | 0.1916 | 0.1035 | 0.3083 | 0.7329 | 0.0005 | 0.0000 | 0.0011 | 0.0001 | 0.0039 | 0.0001 | 0.0150 | 0.0019 | 0.0339 | 0.0136 | 0.0662 | 0.0303 | 0.0676 | 0.0255 | 0.0968 | 0.0435 | 0.7150 | 0.8851 | 0.0033 | 0.0121 | 0.0080 | 0.0260 | 0.0256 | 0.0419 | 0.0756 | 0.1200 | 0.1388 | 0.1842 | 0.1465 | 0.1777 | 0.1385 | 0.1284 | 0.1600 | 0.1265 | 0.3036 | 0.1833 | 0.0009 | 0.0050 | 0.0135 | 0.0414 | 0.0740 | 0.1119 | 0.1069 | 0.1367 | 0.5097 | 27 | 50 | 85 | 129 | 174 | 220 | 274 | 342 | 444 | 0.0030 | 74.43 | 7.191 | 0.2347 | 74701.9 | 35300000 | 20500000000 | 14000000000000 | 0.4914 | 0.1942 | 0.0341 | 0.0005 | 0.1480 | 0.0067 | 0.2568 | 0.0741 | 0.1712 | 0.1263 | 0.1455 | 0.1772 | 0.1169 | 0.1937 | 0.0654 | 0.1449 | 0.0389 | 0.1300 | 0.0232 | 0.1465 | 0.0003 | 0.0001 | 0.0016 | 0.0005 | 0.0037 | 0.0012 | 0.0153 | 0.0094 | 0.0721 | 0.0542 | 0.1302 | 0.1070 | 0.0998 | 0.0805 | 0.1378 | 0.1181 | 0.5392 | 0.6290 | 0.0009 | 0.0021 | 0.0040 | 0.0065 | 0.0122 | 0.0178 | 0.0377 | 0.0512 | 0.1055 | 0.1206 | 0.1719 | 0.1793 | 0.1135 | 0.1149 | 0.1437 | 0.1477 | 0.4105 | 0.3599 | 0.0007 | 0.0020 | 0.0080 | 0.0239 | 0.0873 | 0.1563 | 0.1162 | 0.1382 | 0.4675 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1060 | 148 | | 9173 | 22344 | 294.9 | 54.87 | 142.27 | 167.42 | 227 | 246 | 262 | 276 | 290 | 304 | 321 | 343 | 371 | 0.0689 | 1540 | 0.872 | 128.71 | 44.38 | 1 | 0.0395 | 362 | 0.0007 | 53.70 | 7.461 | 0.1589 | 89976.7 | 28400000 | 9240000000 | 3100000000000 | 0.4189 | 0.2273 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0039 | 0.0000 | 0.0119 | 0.0010 | 0.0544 | 0.0105 | 0.1011 | 0.0239 | 0.1296 | 0.0218 | 0.1648 | 0.0345 | 0.5330 | 0.9084 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0059 | 0.0002 | 0.0246 | 0.0088 | 0.0420 | 0.0180 | 0.0587 | 0.0104 | 0.0811 | 0.0154 | 0.7860 | 0.9472 | 0.0035 | 0.0359 | 0.0110 | 0.0256 | 0.0311 | 0.0769 | 0.0876 | 0.1487 | 0.1090 | 0.1436 | 0.1739 | 0.1641 | 0.1256 | 0.1128 | 0.1387 | 0.1231 | 0.3195 | 0.1692 | 0.0012 | 0.0047 | 0.0077 | 0.0323 | 0.0798 | 0.1131 | 0.0949 | 0.1254 | 0.5411 | 14 | 17 | 22 | 39 | 72 | 114 | 176 | 260 | 379 | 0.0282 | 29.29 | 5.688 | 0.4480 | 48267.7 | 23800000 | 15100000000 | 12000000000000 | 0.5526 | 0.1273 | 0.0495 | 0.0023 | 0.1676 | 0.0182 | 0.2382 | 0.0872 | 0.1820 | 0.1262 | 0.1201 | 0.1819 | 0.1042 | 0.1777 | 0.0735 | 0.1315 | 0.0360 | 0.1131 | 0.0288 | 0.1618 | 0.0010 | 0.0004 | 0.0013 | 0.0008 | 0.0025 | 0.0027 | 0.0122 | 0.0114 | 0.0574 | 0.0459 | 0.1001 | 0.0810 | 0.0689 | 0.0643 | 0.0971 | 0.0872 | 0.6595 | 0.7063 | 0.0003 | 0.0003 | 0.0007 | 0.0013 | 0.0044 | 0.0053 | 0.0173 | 0.0217 | 0.0820 | 0.0881 | 0.1194 | 0.1360 | 0.0834 | 0.0891 | 0.1164 | 0.1154 | 0.5761 | 0.5428 | 0.0005 | 0.0013 | 0.0029 | 0.0153 | 0.0705 | 0.1085 | 0.0767 | 0.1091 | 0.6152 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 849 | 648 | | 5112 | 6565 | 125.8 | 31.35 | 178.35 | 174.51 | 89 | 99 | 108 | 116 | 122 | 129 | 138 | 149 | 167 | 0.1097 | 720 | 1.162 | 109.62 | 38.12 | 1 | 0.0534 | 273 | 0.0023 | 21.62 | 6.373 | 0.2588 | 16819.2 | 2390000 | 363000000 | 58800000000 | 0.4232 | 0.2346 | 0.0006 | 0.0000 | 0.0042 | 0.0000 | 0.0130 | 0.0002 | 0.0250 | 0.0036 | 0.0815 | 0.0212 | 0.1644 | 0.0559 | 0.1624 | 0.0520 | 0.1722 | 0.0780 | 0.3765 | 0.7890 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0012 | 0.0000 | 0.0055 | 0.0006 | 0.0352 | 0.0126 | 0.0852 | 0.0358 | 0.0745 | 0.0194 | 0.0985 | 0.0372 | 0.6986 | 0.8945 | 0.0022 | 0.0030 | 0.0087 | 0.0208 | 0.0282 | 0.0653 | 0.1062 | 0.1187 | 0.1593 | 0.1988 | 0.1907 | 0.1691 | 0.1192 | 0.1128 | 0.1148 | 0.0950 | 0.2709 | 0.2166 | 0.0022 | 0.0052 | 0.0108 | 0.0388 | 0.1086 | 0.1483 | 0.1198 | 0.1362 | 0.4302 | 16 | 28 | 49 | 82 | 120 | 170 | 233 | 311 | 426 | 0.0054 | 96.61 | 6.816 | 0.3013 | 62256.2 | 29200000 | 16400000000 | 10300000000000 | 0.4788 | 0.1616 | 0.0394 | 0.0012 | 0.1386 | 0.0088 | 0.2664 | 0.0649 | 0.1673 | 0.1257 | 0.1589 | 0.1784 | 0.1147 | 0.2041 | 0.0514 | 0.1509 | 0.0346 | 0.1222 | 0.0287 | 0.1439 | 0.0000 | 0.0003 | 0.0007 | 0.0000 | 0.0023 | 0.0011 | 0.0171 | 0.0077 | 0.0635 | 0.0541 | 0.1070 | 0.0913 | 0.0846 | 0.0677 | 0.1084 | 0.1006 | 0.6164 | 0.6772 | 0.0009 | 0.0000 | 0.0023 | 0.0028 | 0.0070 | 0.0083 | 0.0232 | 0.0319 | 0.0859 | 0.0979 | 0.1226 | 0.1364 | 0.0878 | 0.0974 | 0.1333 | 0.1320 | 0.5369 | 0.4934 | 0.0008 | 0.0008 | 0.0055 | 0.0169 | 0.0777 | 0.1131 | 0.0868 | 0.1190 | 0.5795 | ||
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 591 | 322 | | 3805 | 8120 | 447.6 | 140.46 | 62.41 | 102.20 | 225 | 309 | 397 | 453 | 481 | 505 | 531 | 568 | 598 | 0.0792 | 643 | 1.179 | 95.75 | 35.78 | 2 | 0.0636 | 242 | 0.0012 | 24.22 | 7.023 | 0.2589 | 220069.0 | 114000000 | 61800000000 | 34400000000000 | 0.3868 | 0.2449 | 0.0017 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0003 | 0.0114 | 0.0030 | 0.0542 | 0.0207 | 0.0787 | 0.0353 | 0.0685 | 0.0267 | 0.1038 | 0.0443 | 0.6805 | 0.8697 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0019 | 0.0183 | 0.0158 | 0.0254 | 0.0260 | 0.0183 | 0.0167 | 0.0268 | 0.0236 | 0.9097 | 0.9160 | 0.0009 | 0.0000 | 0.0037 | 0.0000 | 0.0083 | 0.0000 | 0.0111 | 0.0000 | 0.0426 | 0.0000 | 0.0546 | 0.0000 | 0.0592 | 0.0000 | 0.0823 | 0.0000 | 0.7373 | 1.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0047 | 0.0236 | 0.0356 | 0.0347 | 0.0592 | 0.8404 | 8 | 9 | 11 | 12 | 16 | 24 | 45 | 91 | 190 | 0.1789 | 5.12 | 3.242 | 0.6875 | 14337.8 | 5250000 | 2370000000 | 1220000000000 | 0.6067 | 0.0913 | 0.0581 | 0.0060 | 0.1183 | 0.0249 | 0.1618 | 0.0957 | 0.1390 | 0.1256 | 0.1784 | 0.1446 | 0.1515 | 0.1605 | 0.1224 | 0.1296 | 0.0456 | 0.0987 | 0.0249 | 0.2144 | 0.0017 | 0.0015 | 0.0035 | 0.0026 | 0.0035 | 0.0045 | 0.0138 | 0.0146 | 0.0558 | 0.0544 | 0.0878 | 0.0773 | 0.0636 | 0.0484 | 0.0930 | 0.0926 | 0.6775 | 0.7041 | 0.0005 | 0.0006 | 0.0005 | 0.0006 | 0.0033 | 0.0024 | 0.0169 | 0.0192 | 0.0754 | 0.0800 | 0.1038 | 0.1191 | 0.0644 | 0.0565 | 0.1032 | 0.1179 | 0.6319 | 0.6037 | 0.0010 | 0.0034 | 0.0039 | 0.0186 | 0.0658 | 0.0932 | 0.0677 | 0.0991 | 0.6472 |