High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 666 | 842 | | 12884 | 27221 | 219.0 | 58.92 | 118.73 | 205.47 | 152 | 171 | 185 | 199 | 212 | 227 | 245 | 268 | 298 | 0.0499 | 1359 | 0.808 | 193.62 | 44.05 | 2 | 0.0354 | 456 | 0.0008 | 46.64 | 7.460 | 0.1768 | 51441.8 | 12900000 | 3430000000 | 964000000000 | 0.4180 | 0.2281 | 0.0003 | 0.0001 | 0.0020 | 0.0000 | 0.0075 | 0.0004 | 0.0271 | 0.0027 | 0.0783 | 0.0206 | 0.1403 | 0.0412 | 0.1412 | 0.0459 | 0.1709 | 0.0684 | 0.4325 | 0.8207 | 0.0001 | 0.0000 | 0.0013 | 0.0000 | 0.0023 | 0.0000 | 0.0103 | 0.0014 | 0.0303 | 0.0115 | 0.0505 | 0.0181 | 0.0596 | 0.0180 | 0.0775 | 0.0275 | 0.7681 | 0.9236 | 0.0028 | 0.0068 | 0.0028 | 0.0184 | 0.0137 | 0.0261 | 0.0439 | 0.0812 | 0.0847 | 0.1285 | 0.1612 | 0.1865 | 0.1135 | 0.0889 | 0.1377 | 0.1449 | 0.4398 | 0.3188 | 0.0017 | 0.0044 | 0.0094 | 0.0269 | 0.0584 | 0.0906 | 0.0952 | 0.1178 | 0.5957 | 12 | 14 | 16 | 19 | 23 | 35 | 81 | 186 | 369 | 0.1090 | 28.98 | 4.298 | 0.6029 | 56311.6 | 43400000 | 43600000000 | 52400000000000 | 0.4887 | 0.1540 | 0.1380 | 0.0057 | 0.3027 | 0.0505 | 0.2534 | 0.2149 | 0.1170 | 0.1937 | 0.0888 | 0.2013 | 0.0605 | 0.1398 | 0.0282 | 0.0765 | 0.0105 | 0.0629 | 0.0008 | 0.0547 | 0.0000 | 0.0004 | 0.0018 | 0.0008 | 0.0016 | 0.0015 | 0.0149 | 0.0108 | 0.0607 | 0.0575 | 0.0912 | 0.0799 | 0.0683 | 0.0568 | 0.1015 | 0.0892 | 0.6600 | 0.7031 | 0.0005 | 0.0000 | 0.0008 | 0.0012 | 0.0040 | 0.0058 | 0.0208 | 0.0226 | 0.0784 | 0.0804 | 0.1103 | 0.1258 | 0.0842 | 0.0911 | 0.1132 | 0.1227 | 0.5879 | 0.5503 | 0.0004 | 0.0011 | 0.0027 | 0.0160 | 0.0680 | 0.1060 | 0.0721 | 0.1158 | 0.6178 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1069 | 181 | | 1596 | 20629 | 124.5 | 28.67 | 72.87 | 146.49 | 98 | 102 | 107 | 111 | 116 | 122 | 130 | 143 | 162 | 0.0438 | 904 | 0.809 | 207.96 | 60.42 | 1 | 0.3440 | 549 | 0.0093 | 6.72 | 5.134 | 0.4357 | 16321.0 | 2270000 | 339000000 | 54100000000 | 0.4382 | 0.2050 | 0.0064 | 0.0000 | 0.0064 | 0.0000 | 0.0091 | 0.0000 | 0.0246 | 0.0027 | 0.0665 | 0.0317 | 0.0938 | 0.0661 | 0.1084 | 0.0465 | 0.1321 | 0.0715 | 0.5528 | 0.7815 | 0.0051 | 0.0000 | 0.0044 | 0.0000 | 0.0066 | 0.0000 | 0.0139 | 0.0025 | 0.0285 | 0.0257 | 0.0446 | 0.0426 | 0.0599 | 0.0238 | 0.0833 | 0.0401 | 0.7538 | 0.8653 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0111 | 0.0000 | 0.0406 | 0.0000 | 0.1144 | 0.0000 | 0.1476 | 0.0000 | 0.1144 | 0.0000 | 0.1255 | 0.0000 | 0.4428 | 0.0000 | 0.0016 | 0.0081 | 0.0049 | 0.0357 | 0.0535 | 0.1086 | 0.0729 | 0.1135 | 0.6013 | 7 | 9 | 11 | 12 | 13 | 15 | 19 | 61 | 281 | 0.2995 | 21.07 | 3.063 | 0.7088 | 26767.6 | 14200000 | 8950000000 | 6390000000000 | 0.3754 | 0.2426 | 0.1380 | 0.0048 | 0.3646 | 0.0530 | 0.2760 | 0.2133 | 0.1250 | 0.2337 | 0.0781 | 0.2422 | 0.0156 | 0.1627 | 0.0026 | 0.0590 | 0.0000 | 0.0217 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0005 | 0.0062 | 0.0050 | 0.0345 | 0.0311 | 0.0536 | 0.0493 | 0.0409 | 0.0369 | 0.0551 | 0.0516 | 0.8092 | 0.8256 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0018 | 0.0030 | 0.0082 | 0.0075 | 0.0356 | 0.0413 | 0.0757 | 0.0865 | 0.0522 | 0.0543 | 0.0707 | 0.0848 | 0.7559 | 0.7221 | 0.0000 | 0.0003 | 0.0008 | 0.0058 | 0.0340 | 0.0678 | 0.0421 | 0.0646 | 0.7846 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 179 | 861 | | 6894 | 24993 | 432.7 | 77.04 | 123.09 | 229.52 | 337 | 363 | 385 | 406 | 427 | 448 | 470 | 497 | 536 | 0.0541 | 1352 | 1.247 | 106.10 | 42.20 | 2 | 0.0392 | 270 | 0.0024 | 14.62 | 6.292 | 0.2830 | 193164.0 | 88900000 | 42200000000 | 20600000000000 | 0.4573 | 0.1908 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0034 | 0.0000 | 0.0121 | 0.0006 | 0.0472 | 0.0149 | 0.0960 | 0.0253 | 0.1212 | 0.0267 | 0.1545 | 0.0354 | 0.5647 | 0.8972 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0065 | 0.0001 | 0.0253 | 0.0121 | 0.0467 | 0.0177 | 0.0549 | 0.0126 | 0.0783 | 0.0167 | 0.7863 | 0.9408 | 0.0053 | 0.0000 | 0.0160 | 0.0701 | 0.0299 | 0.0764 | 0.0812 | 0.1783 | 0.1335 | 0.1720 | 0.1656 | 0.1783 | 0.1186 | 0.1274 | 0.1346 | 0.0955 | 0.3152 | 0.1019 | 0.0009 | 0.0037 | 0.0079 | 0.0244 | 0.0711 | 0.1200 | 0.1053 | 0.1236 | 0.5430 | 8 | 10 | 12 | 13 | 16 | 23 | 63 | 188 | 422 | 0.2078 | 29.75 | 3.972 | 0.6370 | 67827.8 | 55500000 | 55600000000 | 63900000000000 | 0.4521 | 0.1694 | 0.1333 | 0.0042 | 0.3651 | 0.0371 | 0.3035 | 0.2123 | 0.1120 | 0.2751 | 0.0504 | 0.2537 | 0.0202 | 0.1124 | 0.0090 | 0.0570 | 0.0045 | 0.0314 | 0.0022 | 0.0167 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0014 | 0.0008 | 0.0135 | 0.0108 | 0.0527 | 0.0490 | 0.0825 | 0.0789 | 0.0578 | 0.0500 | 0.0808 | 0.0738 | 0.7110 | 0.7365 | 0.0002 | 0.0004 | 0.0009 | 0.0010 | 0.0018 | 0.0029 | 0.0147 | 0.0130 | 0.0575 | 0.0617 | 0.0963 | 0.1072 | 0.0686 | 0.0675 | 0.0945 | 0.1032 | 0.6655 | 0.6432 | 0.0007 | 0.0005 | 0.0013 | 0.0119 | 0.0549 | 0.0931 | 0.0549 | 0.0860 | 0.6968 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 376 | 670 | | 11475 | 30585 | 465.6 | 100.42 | 131.66 | 237.18 | 350 | 378 | 401 | 424 | 447 | 473 | 505 | 551 | 622 | 0.0430 | 1316 | 1.157 | 137.30 | 49.41 | 1 | 0.0297 | 341 | 0.0015 | 21.13 | 6.886 | 0.2666 | 226895.0 | 116000000 | 61700000000 | 34300000000000 | 0.4225 | 0.2239 | 0.0007 | 0.0000 | 0.0015 | 0.0002 | 0.0037 | 0.0005 | 0.0127 | 0.0019 | 0.0414 | 0.0147 | 0.0727 | 0.0296 | 0.0882 | 0.0265 | 0.1258 | 0.0409 | 0.6532 | 0.8857 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0014 | 0.0000 | 0.0059 | 0.0002 | 0.0182 | 0.0083 | 0.0338 | 0.0145 | 0.0420 | 0.0091 | 0.0610 | 0.0147 | 0.8365 | 0.9533 | 0.0028 | 0.0121 | 0.0080 | 0.0151 | 0.0099 | 0.0302 | 0.0274 | 0.0710 | 0.0690 | 0.1480 | 0.0922 | 0.1631 | 0.0813 | 0.1329 | 0.1068 | 0.1647 | 0.6026 | 0.2628 | 0.0008 | 0.0026 | 0.0051 | 0.0240 | 0.0431 | 0.0825 | 0.0785 | 0.0990 | 0.6644 | 5 | 6 | 8 | 9 | 12 | 26 | 86 | 218 | 471 | 0.1403 | 63.23 | 4.504 | 0.5576 | 73585.6 | 57500000 | 53700000000 | 56800000000000 | 0.4673 | 0.1625 | 0.0887 | 0.0045 | 0.2607 | 0.0499 | 0.2554 | 0.2123 | 0.1210 | 0.1544 | 0.1082 | 0.1653 | 0.0736 | 0.1423 | 0.0413 | 0.0927 | 0.0316 | 0.0855 | 0.0195 | 0.0931 | 0.0001 | 0.0000 | 0.0005 | 0.0003 | 0.0014 | 0.0003 | 0.0066 | 0.0066 | 0.0477 | 0.0419 | 0.0761 | 0.0690 | 0.0508 | 0.0460 | 0.0878 | 0.0763 | 0.7290 | 0.7595 | 0.0001 | 0.0001 | 0.0001 | 0.0010 | 0.0019 | 0.0016 | 0.0087 | 0.0121 | 0.0598 | 0.0631 | 0.0938 | 0.0985 | 0.0624 | 0.0744 | 0.1049 | 0.1107 | 0.6681 | 0.6384 | 0.0003 | 0.0003 | 0.0015 | 0.0081 | 0.0555 | 0.0813 | 0.0601 | 0.0971 | 0.6958 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 948 | 93 | | 6191 | 5411 | 97.2 | 28.78 | 176.56 | 250.57 | 65 | 74 | 81 | 88 | 94 | 101 | 108 | 118 | 134 | 0.1785 | 966 | 0.915 | 160.59 | 50.92 | 3 | 0.0728 | 451 | 0.0012 | 44.43 | 7.019 | 0.1810 | 10281.0 | 1180000 | 147000000 | 20000000000 | 0.4296 | 0.2140 | 0.0006 | 0.0000 | 0.0021 | 0.0000 | 0.0200 | 0.0011 | 0.0445 | 0.0080 | 0.1179 | 0.0337 | 0.1765 | 0.0649 | 0.1815 | 0.0792 | 0.1824 | 0.1193 | 0.2744 | 0.6938 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0003 | 0.0120 | 0.0043 | 0.0482 | 0.0193 | 0.0816 | 0.0358 | 0.0819 | 0.0379 | 0.1103 | 0.0573 | 0.6632 | 0.8451 | 0.0046 | 0.0144 | 0.0144 | 0.0341 | 0.0311 | 0.0485 | 0.0971 | 0.0987 | 0.1115 | 0.1813 | 0.1624 | 0.1418 | 0.1252 | 0.0987 | 0.1373 | 0.1275 | 0.3164 | 0.2549 | 0.0028 | 0.0059 | 0.0121 | 0.0385 | 0.0905 | 0.1273 | 0.1099 | 0.1328 | 0.4802 | 19 | 24 | 31 | 44 | 66 | 104 | 177 | 282 | 478 | 0.0405 | 26.68 | 4.951 | 0.5100 | 93949.7 | 80000000 | 85800000000 | 105000000000000 | 0.6057 | 0.0948 | 0.1074 | 0.0033 | 0.2729 | 0.0546 | 0.2550 | 0.2116 | 0.1208 | 0.1860 | 0.1230 | 0.1815 | 0.0582 | 0.1503 | 0.0425 | 0.0846 | 0.0201 | 0.0579 | 0.0000 | 0.0702 | 0.0005 | 0.0005 | 0.0043 | 0.0019 | 0.0086 | 0.0075 | 0.0311 | 0.0230 | 0.1063 | 0.0962 | 0.1283 | 0.1304 | 0.1063 | 0.0863 | 0.1546 | 0.1487 | 0.4600 | 0.5056 | 0.0007 | 0.0016 | 0.0071 | 0.0049 | 0.0127 | 0.0138 | 0.0438 | 0.0454 | 0.1243 | 0.1410 | 0.1653 | 0.1896 | 0.1165 | 0.1135 | 0.1645 | 0.1564 | 0.3651 | 0.3339 | 0.0018 | 0.0037 | 0.0098 | 0.0331 | 0.1227 | 0.1466 | 0.1110 | 0.1724 | 0.3988 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 154 | 616 | | 4931 | 13584 | 338.0 | 75.06 | 151.28 | 225.61 | 248 | 276 | 297 | 314 | 331 | 349 | 369 | 393 | 435 | 0.0692 | 940 | 1.116 | 97.91 | 41.00 | 1 | 0.0548 | 270 | 0.0006 | 91.32 | 7.643 | 0.1256 | 119887.0 | 44600000 | 17400000000 | 7130000000000 | 0.4061 | 0.2399 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0049 | 0.0002 | 0.0161 | 0.0013 | 0.0686 | 0.0206 | 0.1481 | 0.0465 | 0.1372 | 0.0463 | 0.1734 | 0.0725 | 0.4504 | 0.8126 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0017 | 0.0000 | 0.0077 | 0.0006 | 0.0334 | 0.0152 | 0.0762 | 0.0307 | 0.0589 | 0.0239 | 0.0885 | 0.0392 | 0.7329 | 0.8904 | 0.0049 | 0.0081 | 0.0173 | 0.0242 | 0.0260 | 0.0524 | 0.0803 | 0.0968 | 0.1224 | 0.1694 | 0.1706 | 0.1653 | 0.0952 | 0.1250 | 0.1323 | 0.1169 | 0.3511 | 0.2419 | 0.0026 | 0.0062 | 0.0132 | 0.0352 | 0.0835 | 0.1266 | 0.0976 | 0.1196 | 0.5156 | 12 | 15 | 17 | 21 | 30 | 64 | 148 | 279 | 478 | 0.0547 | 37.91 | 5.028 | 0.5176 | 73778.3 | 50900000 | 41900000000 | 39000000000000 | 0.5433 | 0.1208 | 0.1000 | 0.0025 | 0.2590 | 0.0318 | 0.2667 | 0.2116 | 0.1359 | 0.1906 | 0.0692 | 0.1957 | 0.0628 | 0.1449 | 0.0590 | 0.0870 | 0.0308 | 0.0654 | 0.0167 | 0.0705 | 0.0005 | 0.0000 | 0.0002 | 0.0004 | 0.0014 | 0.0018 | 0.0110 | 0.0108 | 0.0529 | 0.0494 | 0.0964 | 0.0818 | 0.0669 | 0.0566 | 0.1009 | 0.0895 | 0.6698 | 0.7097 | 0.0003 | 0.0003 | 0.0008 | 0.0009 | 0.0019 | 0.0021 | 0.0109 | 0.0162 | 0.0702 | 0.0748 | 0.1117 | 0.1200 | 0.0803 | 0.0967 | 0.1268 | 0.1281 | 0.5970 | 0.5609 | 0.0000 | 0.0025 | 0.0025 | 0.0099 | 0.0656 | 0.0992 | 0.0705 | 0.1173 | 0.6325 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 686 | 761 | | 4278 | 10329 | 575.0 | 101.74 | 209.00 | 348.06 | 451 | 485 | 515 | 540 | 564 | 591 | 619 | 660 | 717 | 0.0947 | 978 | 1.233 | 88.57 | 39.70 | 1 | 0.0570 | 244 | 0.0015 | 26.90 | 6.732 | 0.2213 | 340946.0 | 208000000 | 131000000000 | 85100000000000 | 0.4370 | 0.2089 | 0.0003 | 0.0002 | 0.0016 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0005 | 0.0491 | 0.0165 | 0.1035 | 0.0326 | 0.1032 | 0.0271 | 0.1478 | 0.0398 | 0.5865 | 0.8833 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0005 | 0.0000 | 0.0035 | 0.0002 | 0.0289 | 0.0138 | 0.0516 | 0.0248 | 0.0503 | 0.0145 | 0.0751 | 0.0227 | 0.7893 | 0.9239 | 0.0017 | 0.0000 | 0.0017 | 0.0408 | 0.0166 | 0.0510 | 0.0582 | 0.1633 | 0.1481 | 0.2041 | 0.1681 | 0.2245 | 0.0899 | 0.0714 | 0.1514 | 0.1633 | 0.3644 | 0.0816 | 0.0010 | 0.0000 | 0.0051 | 0.0314 | 0.0663 | 0.1352 | 0.1023 | 0.1180 | 0.5408 | 9 | 10 | 12 | 14 | 19 | 49 | 188 | 394 | 707 | 0.1793 | 74.24 | 4.505 | 0.5801 | 164813.0 | 178000000 | 227000000000 | 323000000000000 | 0.5252 | 0.1228 | 0.1229 | 0.0022 | 0.3301 | 0.0673 | 0.2337 | 0.2076 | 0.1108 | 0.1987 | 0.0723 | 0.2065 | 0.0723 | 0.1358 | 0.0313 | 0.0550 | 0.0193 | 0.0673 | 0.0072 | 0.0595 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0013 | 0.0020 | 0.0041 | 0.0055 | 0.0525 | 0.0486 | 0.0965 | 0.0858 | 0.0600 | 0.0532 | 0.0839 | 0.0776 | 0.7008 | 0.7272 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0014 | 0.0012 | 0.0090 | 0.0196 | 0.0690 | 0.0667 | 0.1063 | 0.1181 | 0.0788 | 0.0895 | 0.1095 | 0.1071 | 0.6259 | 0.5958 | 0.0000 | 0.0003 | 0.0000 | 0.0104 | 0.0509 | 0.1031 | 0.0686 | 0.0961 | 0.6707 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1028 | 231 | | 11368 | 9358 | 393.3 | 133.58 | 93.30 | 136.68 | 187 | 274 | 336 | 383 | 422 | 451 | 481 | 509 | 544 | 0.1038 | 971 | 0.530 | 101.02 | 17.03 | 7 | 0.0223 | 254 | 0.0009 | 24.62 | 7.358 | 0.2464 | 172513.0 | 80400000 | 39000000000 | 19500000000000 | 0.5210 | 0.1387 | 0.0011 | 0.0006 | 0.0017 | 0.0005 | 0.0047 | 0.0018 | 0.0170 | 0.0049 | 0.0766 | 0.0277 | 0.1275 | 0.0545 | 0.1031 | 0.0384 | 0.1389 | 0.0594 | 0.5294 | 0.8122 | 0.0000 | 0.0001 | 0.0001 | 0.0001 | 0.0000 | 0.0002 | 0.0023 | 0.0012 | 0.0230 | 0.0184 | 0.0392 | 0.0346 | 0.0241 | 0.0188 | 0.0387 | 0.0285 | 0.8726 | 0.8980 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0061 | 0.0000 | 0.0163 | 0.0000 | 0.0472 | 0.0000 | 0.0674 | 0.0000 | 0.0653 | 0.0000 | 0.0888 | 0.0000 | 0.7054 | 1.0000 | 0.0003 | 0.0002 | 0.0009 | 0.0047 | 0.0314 | 0.0487 | 0.0382 | 0.0542 | 0.8214 | 10 | 12 | 15 | 20 | 34 | 52 | 79 | 150 | 276 | 0.1156 | 10.49 | 4.045 | 0.6216 | 27384.8 | 12500000 | 7130000000 | 4620000000000 | 0.4672 | 0.1594 | 0.0875 | 0.0139 | 0.2611 | 0.0541 | 0.2439 | 0.2073 | 0.1148 | 0.1314 | 0.0933 | 0.1294 | 0.0689 | 0.1208 | 0.0473 | 0.0812 | 0.0445 | 0.0759 | 0.0387 | 0.1861 | 0.0003 | 0.0020 | 0.0031 | 0.0022 | 0.0037 | 0.0053 | 0.0252 | 0.0193 | 0.0857 | 0.0735 | 0.1244 | 0.1092 | 0.0857 | 0.0732 | 0.1163 | 0.1151 | 0.5556 | 0.6003 | 0.0000 | 0.0000 | 0.0004 | 0.0010 | 0.0045 | 0.0077 | 0.0254 | 0.0305 | 0.0994 | 0.1056 | 0.1582 | 0.1608 | 0.0856 | 0.0944 | 0.1270 | 0.1370 | 0.4996 | 0.4630 | 0.0008 | 0.0044 | 0.0044 | 0.0252 | 0.0913 | 0.1442 | 0.0873 | 0.1197 | 0.5226 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 207 | 478 | | 13048 | 26519 | 97.0 | 27.99 | 161.98 | 234.77 | 64 | 74 | 81 | 88 | 95 | 102 | 109 | 119 | 134 | 0.0514 | 1363 | 0.414 | 318.40 | 44.82 | 2 | 0.0676 | 882 | 0.0022 | 19.38 | 6.429 | 0.2488 | 10191.1 | 1150000 | 139000000 | 17800000000 | 0.4486 | 0.1898 | 0.0006 | 0.0001 | 0.0026 | 0.0001 | 0.0142 | 0.0005 | 0.0573 | 0.0057 | 0.1294 | 0.0245 | 0.1873 | 0.0596 | 0.1931 | 0.0819 | 0.1988 | 0.1265 | 0.2168 | 0.7010 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0002 | 0.0123 | 0.0021 | 0.0425 | 0.0125 | 0.0796 | 0.0275 | 0.0907 | 0.0335 | 0.1311 | 0.0529 | 0.6415 | 0.8713 | 0.0086 | 0.0180 | 0.0124 | 0.0237 | 0.0341 | 0.0606 | 0.0834 | 0.1219 | 0.1405 | 0.1457 | 0.1777 | 0.1833 | 0.1230 | 0.1129 | 0.1467 | 0.1211 | 0.2735 | 0.2128 | 0.0013 | 0.0034 | 0.0092 | 0.0433 | 0.0938 | 0.1445 | 0.1259 | 0.1491 | 0.4295 | 12 | 14 | 16 | 18 | 33 | 81 | 172 | 311 | 501 | 0.1539 | 30.24 | 4.603 | 0.5818 | 81353.0 | 57600000 | 49500000000 | 48800000000000 | 0.6313 | 0.0832 | 0.0968 | 0.0061 | 0.2891 | 0.0382 | 0.3119 | 0.2073 | 0.1514 | 0.1858 | 0.0786 | 0.1931 | 0.0396 | 0.1633 | 0.0221 | 0.0966 | 0.0084 | 0.0664 | 0.0019 | 0.0433 | 0.0002 | 0.0001 | 0.0014 | 0.0006 | 0.0029 | 0.0019 | 0.0159 | 0.0126 | 0.0664 | 0.0555 | 0.1013 | 0.0925 | 0.0752 | 0.0680 | 0.1062 | 0.0957 | 0.6305 | 0.6731 | 0.0001 | 0.0004 | 0.0027 | 0.0026 | 0.0041 | 0.0069 | 0.0213 | 0.0238 | 0.0829 | 0.0859 | 0.1261 | 0.1347 | 0.0905 | 0.1014 | 0.1246 | 0.1340 | 0.5478 | 0.5103 | 0.0002 | 0.0021 | 0.0035 | 0.0166 | 0.0752 | 0.1103 | 0.0892 | 0.1185 | 0.5844 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1078 | 523 | | 14942 | 30535 | 213.6 | 65.41 | 182.99 | 225.98 | 137 | 159 | 176 | 193 | 208 | 224 | 242 | 265 | 299 | 0.0495 | 1511 | 0.501 | 139.13 | 33.29 | 9 | 0.0285 | 426 | 0.0011 | 32.46 | 7.146 | 0.2116 | 49882.5 | 12600000 | 3430000000 | 996000000000 | 0.4707 | 0.1872 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0114 | 0.0010 | 0.0396 | 0.0054 | 0.1050 | 0.0284 | 0.1755 | 0.0659 | 0.1723 | 0.0644 | 0.1742 | 0.0921 | 0.3187 | 0.7427 | 0.0005 | 0.0000 | 0.0007 | 0.0001 | 0.0015 | 0.0002 | 0.0105 | 0.0022 | 0.0389 | 0.0148 | 0.0680 | 0.0352 | 0.0666 | 0.0291 | 0.0852 | 0.0452 | 0.7281 | 0.8731 | 0.0023 | 0.0054 | 0.0057 | 0.0075 | 0.0154 | 0.0299 | 0.0570 | 0.0680 | 0.1115 | 0.1497 | 0.1591 | 0.1844 | 0.1081 | 0.1163 | 0.1420 | 0.1306 | 0.3989 | 0.3082 | 0.0007 | 0.0032 | 0.0068 | 0.0241 | 0.0727 | 0.1106 | 0.0894 | 0.1272 | 0.5653 | 7 | 9 | 13 | 25 | 64 | 146 | 254 | 375 | 525 | 0.0542 | 24.53 | 5.282 | 0.4416 | 84546.7 | 50200000 | 34700000000 | 26800000000000 | 0.4917 | 0.1628 | 0.0917 | 0.0009 | 0.2762 | 0.0235 | 0.3457 | 0.2055 | 0.1342 | 0.1964 | 0.0753 | 0.2196 | 0.0473 | 0.1648 | 0.0208 | 0.0975 | 0.0068 | 0.0592 | 0.0019 | 0.0325 | 0.0001 | 0.0000 | 0.0004 | 0.0004 | 0.0005 | 0.0007 | 0.0084 | 0.0060 | 0.0544 | 0.0468 | 0.0935 | 0.0840 | 0.0596 | 0.0515 | 0.0953 | 0.0815 | 0.6877 | 0.7291 | 0.0001 | 0.0001 | 0.0001 | 0.0004 | 0.0013 | 0.0016 | 0.0121 | 0.0199 | 0.0750 | 0.0811 | 0.1193 | 0.1295 | 0.0741 | 0.0859 | 0.1155 | 0.1244 | 0.6026 | 0.5571 | 0.0002 | 0.0002 | 0.0006 | 0.0101 | 0.0639 | 0.1058 | 0.0698 | 0.1080 | 0.6414 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1162 | 577 | | 13856 | 32218 | 412.2 | 88.94 | 164.83 | 232.07 | 304 | 336 | 360 | 380 | 402 | 425 | 452 | 487 | 537 | 0.0416 | 1339 | 1.120 | 120.08 | 40.36 | 1 | 0.0211 | 292 | 0.0008 | 47.91 | 7.432 | 0.1705 | 177845.0 | 80200000 | 37700000000 | 18400000000000 | 0.4301 | 0.2191 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0005 | 0.0112 | 0.0023 | 0.0595 | 0.0147 | 0.1409 | 0.0309 | 0.1350 | 0.0320 | 0.1666 | 0.0506 | 0.4830 | 0.8691 | 0.0002 | 0.0000 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0045 | 0.0001 | 0.0264 | 0.0081 | 0.0665 | 0.0180 | 0.0589 | 0.0144 | 0.0831 | 0.0249 | 0.7596 | 0.9345 | 0.0043 | 0.0042 | 0.0036 | 0.0198 | 0.0213 | 0.0353 | 0.0588 | 0.0791 | 0.1113 | 0.1638 | 0.1552 | 0.1751 | 0.0991 | 0.1455 | 0.1204 | 0.1780 | 0.4260 | 0.1992 | 0.0009 | 0.0044 | 0.0096 | 0.0313 | 0.0768 | 0.1126 | 0.0944 | 0.1160 | 0.5540 | 7 | 9 | 11 | 18 | 43 | 99 | 192 | 328 | 498 | 0.0842 | 39.05 | 5.161 | 0.4769 | 81023.3 | 55900000 | 47700000000 | 47900000000000 | 0.4243 | 0.2283 | 0.1052 | 0.0021 | 0.2776 | 0.0324 | 0.3170 | 0.2034 | 0.1311 | 0.2094 | 0.0802 | 0.1990 | 0.0495 | 0.1459 | 0.0226 | 0.0876 | 0.0101 | 0.0631 | 0.0067 | 0.0571 | 0.0001 | 0.0001 | 0.0002 | 0.0002 | 0.0022 | 0.0012 | 0.0101 | 0.0092 | 0.0575 | 0.0513 | 0.1002 | 0.0842 | 0.0707 | 0.0637 | 0.1083 | 0.0944 | 0.6508 | 0.6958 | 0.0003 | 0.0007 | 0.0013 | 0.0009 | 0.0029 | 0.0034 | 0.0145 | 0.0165 | 0.0744 | 0.0808 | 0.1140 | 0.1269 | 0.0875 | 0.0901 | 0.1225 | 0.1277 | 0.5827 | 0.5529 | 0.0002 | 0.0008 | 0.0020 | 0.0126 | 0.0667 | 0.1066 | 0.0805 | 0.1167 | 0.6140 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1083 | 712 | | 14567 | 23345 | 228.3 | 65.80 | 245.84 | 294.83 | 149 | 171 | 189 | 204 | 221 | 238 | 259 | 283 | 318 | 0.0544 | 1269 | 0.975 | 95.05 | 27.31 | 2 | 0.0162 | 236 | 0.0009 | 39.78 | 7.247 | 0.1948 | 56452.3 | 15000000 | 4270000000 | 1290000000000 | 0.4024 | 0.2555 | 0.0004 | 0.0000 | 0.0033 | 0.0002 | 0.0132 | 0.0010 | 0.0356 | 0.0063 | 0.1124 | 0.0290 | 0.1854 | 0.0626 | 0.1649 | 0.0652 | 0.1702 | 0.0924 | 0.3145 | 0.7434 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0018 | 0.0001 | 0.0102 | 0.0020 | 0.0384 | 0.0138 | 0.0759 | 0.0319 | 0.0663 | 0.0284 | 0.0851 | 0.0426 | 0.7219 | 0.8812 | 0.0023 | 0.0036 | 0.0040 | 0.0136 | 0.0144 | 0.0300 | 0.0586 | 0.0886 | 0.1114 | 0.1671 | 0.1697 | 0.2064 | 0.1117 | 0.1207 | 0.1400 | 0.1486 | 0.3879 | 0.2214 | 0.0012 | 0.0012 | 0.0051 | 0.0274 | 0.0791 | 0.1243 | 0.1042 | 0.1238 | 0.5337 | 8 | 10 | 17 | 42 | 109 | 218 | 349 | 492 | 669 | 0.0408 | 47.90 | 5.810 | 0.3933 | 147362.0 | 116000000 | 111000000000 | 123000000000000 | 0.4697 | 0.1864 | 0.1067 | 0.0030 | 0.2767 | 0.0213 | 0.3109 | 0.2024 | 0.1380 | 0.1983 | 0.0764 | 0.2125 | 0.0525 | 0.1566 | 0.0183 | 0.0876 | 0.0165 | 0.0554 | 0.0040 | 0.0630 | 0.0002 | 0.0001 | 0.0000 | 0.0000 | 0.0009 | 0.0008 | 0.0096 | 0.0068 | 0.0596 | 0.0493 | 0.0934 | 0.0808 | 0.0646 | 0.0569 | 0.0998 | 0.0835 | 0.6719 | 0.7217 | 0.0000 | 0.0001 | 0.0005 | 0.0000 | 0.0016 | 0.0021 | 0.0167 | 0.0199 | 0.0781 | 0.0907 | 0.1165 | 0.1342 | 0.0867 | 0.0938 | 0.1227 | 0.1335 | 0.5771 | 0.5256 | 0.0000 | 0.0001 | 0.0009 | 0.0116 | 0.0678 | 0.1051 | 0.0737 | 0.1126 | 0.6282 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 346 | 701 | | 14198 | 40387 | 106.4 | 32.10 | 146.17 | 188.92 | 72 | 82 | 90 | 96 | 103 | 110 | 118 | 129 | 144 | 0.0393 | 1589 | 0.755 | 201.22 | 48.27 | 2 | 0.0373 | 529 | 0.0026 | 18.07 | 6.363 | 0.2881 | 12345.6 | 1580000 | 229000000 | 39000000000 | 0.4708 | 0.1852 | 0.0007 | 0.0001 | 0.0041 | 0.0010 | 0.0119 | 0.0011 | 0.0333 | 0.0042 | 0.0850 | 0.0218 | 0.1598 | 0.0539 | 0.1708 | 0.0533 | 0.1970 | 0.0847 | 0.3372 | 0.7798 | 0.0002 | 0.0000 | 0.0011 | 0.0001 | 0.0015 | 0.0003 | 0.0096 | 0.0013 | 0.0331 | 0.0130 | 0.0687 | 0.0281 | 0.0706 | 0.0210 | 0.1052 | 0.0352 | 0.7101 | 0.9010 | 0.0061 | 0.0103 | 0.0105 | 0.0240 | 0.0243 | 0.0326 | 0.0723 | 0.1021 | 0.1348 | 0.1501 | 0.1713 | 0.1827 | 0.1203 | 0.1226 | 0.1413 | 0.1389 | 0.3190 | 0.2367 | 0.0017 | 0.0051 | 0.0119 | 0.0353 | 0.0818 | 0.1125 | 0.1127 | 0.1276 | 0.5114 | 12 | 14 | 17 | 21 | 38 | 97 | 181 | 289 | 433 | 0.0636 | 63.25 | 5.587 | 0.4594 | 57055.8 | 29900000 | 18300000000 | 12600000000000 | 0.5337 | 0.1336 | 0.0936 | 0.0033 | 0.2406 | 0.0356 | 0.2573 | 0.2023 | 0.1157 | 0.1813 | 0.1154 | 0.1677 | 0.0874 | 0.1514 | 0.0464 | 0.0816 | 0.0283 | 0.0770 | 0.0152 | 0.0996 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0022 | 0.0010 | 0.0084 | 0.0066 | 0.0488 | 0.0425 | 0.1001 | 0.0859 | 0.0667 | 0.0576 | 0.0957 | 0.0872 | 0.6770 | 0.7188 | 0.0006 | 0.0001 | 0.0009 | 0.0017 | 0.0039 | 0.0037 | 0.0107 | 0.0152 | 0.0648 | 0.0721 | 0.1272 | 0.1439 | 0.0905 | 0.0989 | 0.1204 | 0.1231 | 0.5809 | 0.5414 | 0.0005 | 0.0010 | 0.0023 | 0.0103 | 0.0565 | 0.1095 | 0.0807 | 0.1143 | 0.6250 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 902 | 772 | | 9805 | 18751 | 104.4 | 27.00 | 104.60 | 154.09 | 71 | 82 | 90 | 97 | 104 | 110 | 117 | 126 | 139 | 0.0633 | 1186 | 1.212 | 43.08 | 15.81 | 3 | 0.0114 | 112 | 0.0025 | 16.76 | 6.319 | 0.2683 | 11632.2 | 1370000 | 170000000 | 22000000000 | 0.4240 | 0.2204 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0088 | 0.0007 | 0.0337 | 0.0037 | 0.0934 | 0.0179 | 0.1645 | 0.0465 | 0.1821 | 0.0638 | 0.1963 | 0.0903 | 0.3200 | 0.7770 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0001 | 0.0076 | 0.0017 | 0.0290 | 0.0096 | 0.0611 | 0.0214 | 0.0697 | 0.0191 | 0.0939 | 0.0324 | 0.7359 | 0.9158 | 0.0079 | 0.0174 | 0.0153 | 0.0349 | 0.0227 | 0.0654 | 0.0811 | 0.1497 | 0.1293 | 0.1715 | 0.1688 | 0.2035 | 0.1433 | 0.1206 | 0.1539 | 0.1206 | 0.2777 | 0.1163 | 0.0006 | 0.0026 | 0.0102 | 0.0307 | 0.0718 | 0.1201 | 0.1160 | 0.1498 | 0.4982 | 11 | 13 | 15 | 19 | 27 | 52 | 104 | 180 | 312 | 0.1458 | 19.88 | 4.207 | 0.6121 | 34684.3 | 18400000 | 13400000000 | 12900000000000 | 0.5548 | 0.1144 | 0.1016 | 0.0053 | 0.2744 | 0.0473 | 0.2848 | 0.2020 | 0.1392 | 0.1879 | 0.0992 | 0.2113 | 0.0544 | 0.1673 | 0.0200 | 0.0877 | 0.0168 | 0.0513 | 0.0096 | 0.0400 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0014 | 0.0010 | 0.0124 | 0.0106 | 0.0714 | 0.0584 | 0.1103 | 0.0965 | 0.0716 | 0.0610 | 0.1148 | 0.1027 | 0.6169 | 0.6690 | 0.0000 | 0.0002 | 0.0014 | 0.0022 | 0.0034 | 0.0082 | 0.0241 | 0.0253 | 0.0928 | 0.1033 | 0.1418 | 0.1582 | 0.0932 | 0.1072 | 0.1495 | 0.1476 | 0.4938 | 0.4478 | 0.0004 | 0.0007 | 0.0034 | 0.0164 | 0.0820 | 0.1252 | 0.0852 | 0.1331 | 0.5536 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 324 | 279 | | 6286 | 20006 | 305.6 | 53.57 | 177.79 | 250.83 | 239 | 259 | 274 | 287 | 301 | 315 | 332 | 350 | 378 | 0.0542 | 1084 | 0.945 | 142.17 | 51.55 | 2 | 0.0668 | 420 | 0.0007 | 75.58 | 7.460 | 0.1491 | 96237.5 | 31200000 | 10400000000 | 3590000000000 | 0.4372 | 0.2228 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0141 | 0.0008 | 0.0512 | 0.0156 | 0.1137 | 0.0312 | 0.1268 | 0.0255 | 0.1662 | 0.0398 | 0.5258 | 0.8871 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0008 | 0.0262 | 0.0137 | 0.0626 | 0.0247 | 0.0593 | 0.0137 | 0.0930 | 0.0204 | 0.7543 | 0.9266 | 0.0036 | 0.0263 | 0.0238 | 0.0614 | 0.0321 | 0.0965 | 0.1021 | 0.2018 | 0.1437 | 0.1228 | 0.1698 | 0.2018 | 0.1235 | 0.0965 | 0.1508 | 0.0789 | 0.2506 | 0.1140 | 0.0017 | 0.0031 | 0.0099 | 0.0393 | 0.0866 | 0.1598 | 0.1071 | 0.1509 | 0.4417 | 14 | 17 | 19 | 22 | 29 | 66 | 192 | 371 | 581 | 0.0763 | 47.24 | 5.186 | 0.5166 | 94523.5 | 65400000 | 51600000000 | 44600000000000 | 0.4627 | 0.1598 | 0.0782 | 0.0011 | 0.2848 | 0.0210 | 0.3458 | 0.2017 | 0.1338 | 0.2254 | 0.0835 | 0.2125 | 0.0407 | 0.1528 | 0.0193 | 0.0780 | 0.0107 | 0.0511 | 0.0032 | 0.0565 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0008 | 0.0068 | 0.0056 | 0.0457 | 0.0401 | 0.0822 | 0.0776 | 0.0528 | 0.0434 | 0.0755 | 0.0672 | 0.7357 | 0.7653 | 0.0007 | 0.0004 | 0.0010 | 0.0004 | 0.0035 | 0.0019 | 0.0091 | 0.0124 | 0.0540 | 0.0569 | 0.0920 | 0.0927 | 0.0588 | 0.0732 | 0.0952 | 0.0987 | 0.6857 | 0.6635 | 0.0000 | 0.0000 | 0.0016 | 0.0107 | 0.0503 | 0.0851 | 0.0590 | 0.0788 | 0.7146 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1167 | 689 | | 6111 | 11010 | 86.5 | 25.63 | 194.11 | 227.36 | 55 | 64 | 71 | 78 | 84 | 91 | 98 | 107 | 121 | 0.0750 | 826 | 0.733 | 215.47 | 54.20 | 4 | 0.0928 | 567 | 0.0034 | 11.76 | 5.994 | 0.3193 | 8137.3 | 828575 | 90900000 | 10700000000 | 0.4313 | 0.2183 | 0.0010 | 0.0004 | 0.0045 | 0.0006 | 0.0156 | 0.0018 | 0.0448 | 0.0075 | 0.1171 | 0.0342 | 0.1801 | 0.0744 | 0.1674 | 0.0795 | 0.1944 | 0.1213 | 0.2751 | 0.6804 | 0.0004 | 0.0004 | 0.0011 | 0.0000 | 0.0033 | 0.0004 | 0.0100 | 0.0028 | 0.0462 | 0.0179 | 0.0736 | 0.0369 | 0.0694 | 0.0341 | 0.1040 | 0.0529 | 0.6918 | 0.8547 | 0.0057 | 0.0065 | 0.0086 | 0.0161 | 0.0179 | 0.0581 | 0.0622 | 0.1113 | 0.1237 | 0.1597 | 0.1587 | 0.1968 | 0.1244 | 0.1323 | 0.1494 | 0.1419 | 0.3495 | 0.1774 | 0.0020 | 0.0037 | 0.0116 | 0.0317 | 0.0810 | 0.1161 | 0.1045 | 0.1324 | 0.5170 | 14 | 18 | 27 | 51 | 94 | 159 | 248 | 359 | 533 | 0.0198 | 121.90 | 6.448 | 0.3047 | 89366.6 | 55800000 | 41100000000 | 34000000000000 | 0.4757 | 0.1749 | 0.0822 | 0.0030 | 0.2716 | 0.0287 | 0.3153 | 0.2000 | 0.1093 | 0.1713 | 0.1103 | 0.1866 | 0.0562 | 0.1683 | 0.0416 | 0.0896 | 0.0083 | 0.0733 | 0.0052 | 0.0792 | 0.0007 | 0.0002 | 0.0002 | 0.0008 | 0.0034 | 0.0016 | 0.0104 | 0.0093 | 0.0707 | 0.0599 | 0.1227 | 0.1136 | 0.0860 | 0.0717 | 0.1146 | 0.1087 | 0.5914 | 0.6343 | 0.0006 | 0.0007 | 0.0014 | 0.0039 | 0.0046 | 0.0079 | 0.0149 | 0.0201 | 0.0879 | 0.0911 | 0.1479 | 0.1601 | 0.0948 | 0.0999 | 0.1390 | 0.1443 | 0.5088 | 0.4721 | 0.0003 | 0.0018 | 0.0059 | 0.0132 | 0.0749 | 0.1391 | 0.0892 | 0.1302 | 0.5455 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 621 | 832 | | 10045 | 16653 | 624.4 | 136.14 | 146.38 | 247.89 | 478 | 513 | 544 | 571 | 595 | 625 | 662 | 712 | 830 | 0.0671 | 1118 | 1.208 | 132.46 | 56.89 | 1 | 0.0353 | 355 | 0.0011 | 29.04 | 7.171 | 0.2381 | 408412.0 | 281000000 | 204000000000 | 157000000000000 | 0.4086 | 0.2413 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0007 | 0.0125 | 0.0016 | 0.0328 | 0.0154 | 0.0584 | 0.0291 | 0.0670 | 0.0221 | 0.0956 | 0.0345 | 0.7297 | 0.8966 | 0.0005 | 0.0000 | 0.0006 | 0.0000 | 0.0014 | 0.0000 | 0.0072 | 0.0002 | 0.0161 | 0.0088 | 0.0293 | 0.0152 | 0.0349 | 0.0084 | 0.0505 | 0.0148 | 0.8595 | 0.9526 | 0.0006 | 0.0029 | 0.0069 | 0.0073 | 0.0075 | 0.0190 | 0.0162 | 0.0321 | 0.0643 | 0.1226 | 0.0899 | 0.1431 | 0.0762 | 0.1080 | 0.1043 | 0.1328 | 0.6340 | 0.4321 | 0.0025 | 0.0025 | 0.0069 | 0.0195 | 0.0468 | 0.0683 | 0.0678 | 0.0849 | 0.7009 | 4 | 5 | 6 | 8 | 10 | 19 | 116 | 297 | 537 | 0.1488 | 72.06 | 4.406 | 0.5290 | 82870.7 | 61800000 | 54900000000 | 56100000000000 | 0.4135 | 0.2138 | 0.0751 | 0.0057 | 0.2521 | 0.0378 | 0.2654 | 0.1946 | 0.1669 | 0.1626 | 0.1135 | 0.1847 | 0.0785 | 0.1782 | 0.0234 | 0.1043 | 0.0200 | 0.0796 | 0.0050 | 0.0525 | 0.0000 | 0.0004 | 0.0008 | 0.0011 | 0.0014 | 0.0009 | 0.0050 | 0.0058 | 0.0321 | 0.0227 | 0.0675 | 0.0676 | 0.0431 | 0.0353 | 0.0673 | 0.0584 | 0.7827 | 0.8076 | 0.0009 | 0.0002 | 0.0005 | 0.0005 | 0.0023 | 0.0017 | 0.0068 | 0.0076 | 0.0390 | 0.0463 | 0.0847 | 0.0926 | 0.0513 | 0.0638 | 0.0884 | 0.0938 | 0.7262 | 0.6935 | 0.0000 | 0.0006 | 0.0023 | 0.0088 | 0.0301 | 0.0818 | 0.0496 | 0.0716 | 0.7552 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1197 | 683 | | 3842 | 9565 | 478.9 | 116.21 | 90.11 | 172.80 | 337 | 392 | 429 | 457 | 482 | 506 | 537 | 577 | 631 | 0.0859 | 822 | 0.710 | 156.82 | 38.91 | 4 | 0.1221 | 469 | 0.0007 | 53.66 | 7.428 | 0.1677 | 242853.0 | 129000000 | 70500000000 | 39900000000000 | 0.4854 | 0.1685 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0003 | 0.0110 | 0.0026 | 0.0591 | 0.0372 | 0.0922 | 0.0507 | 0.0761 | 0.0389 | 0.1016 | 0.0595 | 0.6575 | 0.8108 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0048 | 0.0008 | 0.0315 | 0.0304 | 0.0481 | 0.0395 | 0.0344 | 0.0268 | 0.0452 | 0.0392 | 0.8356 | 0.8633 | 0.0025 | 0.0000 | 0.0076 | 0.0000 | 0.0051 | 0.0000 | 0.0242 | 0.0000 | 0.0509 | 0.0000 | 0.0738 | 0.0000 | 0.0725 | 0.0000 | 0.0725 | 0.0000 | 0.6908 | 0.0000 | 0.0010 | 0.0020 | 0.0061 | 0.0137 | 0.0461 | 0.0587 | 0.0613 | 0.0886 | 0.7225 | 9 | 11 | 13 | 14 | 17 | 22 | 47 | 128 | 270 | 0.1570 | 5.23 | 3.104 | 0.6201 | 37975.0 | 27200000 | 25100000000 | 27100000000000 | 0.6578 | 0.0700 | 0.0976 | 0.0024 | 0.2415 | 0.0468 | 0.2512 | 0.1909 | 0.0976 | 0.1741 | 0.1146 | 0.1801 | 0.0951 | 0.1381 | 0.0439 | 0.1092 | 0.0390 | 0.0708 | 0.0195 | 0.0876 | 0.0004 | 0.0000 | 0.0004 | 0.0011 | 0.0039 | 0.0036 | 0.0162 | 0.0184 | 0.0774 | 0.0640 | 0.1086 | 0.1081 | 0.0632 | 0.0669 | 0.0968 | 0.0872 | 0.6331 | 0.6506 | 0.0000 | 0.0005 | 0.0024 | 0.0041 | 0.0042 | 0.0057 | 0.0264 | 0.0316 | 0.0792 | 0.0756 | 0.1216 | 0.1366 | 0.0726 | 0.0694 | 0.0975 | 0.1009 | 0.5961 | 0.5756 | 0.0000 | 0.0022 | 0.0047 | 0.0186 | 0.0768 | 0.1195 | 0.0673 | 0.0928 | 0.6182 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 224 | 664 | | 23929 | 53243 | 235.7 | 71.53 | 198.53 | 308.24 | 140 | 172 | 197 | 217 | 235 | 254 | 274 | 298 | 328 | 0.0344 | 1829 | 0.641 | 165.59 | 39.45 | 7 | 0.0212 | 508 | 0.0005 | 51.67 | 7.813 | 0.1685 | 60653.4 | 16700000 | 4890000000 | 1500000000000 | 0.4168 | 0.2169 | 0.0013 | 0.0002 | 0.0025 | 0.0005 | 0.0085 | 0.0016 | 0.0313 | 0.0057 | 0.0797 | 0.0252 | 0.1433 | 0.0530 | 0.1429 | 0.0600 | 0.1764 | 0.0821 | 0.4142 | 0.7718 | 0.0006 | 0.0002 | 0.0010 | 0.0003 | 0.0020 | 0.0007 | 0.0074 | 0.0028 | 0.0227 | 0.0123 | 0.0429 | 0.0258 | 0.0415 | 0.0237 | 0.0600 | 0.0321 | 0.8218 | 0.9020 | 0.0018 | 0.0071 | 0.0045 | 0.0102 | 0.0154 | 0.0252 | 0.0432 | 0.0885 | 0.0873 | 0.1322 | 0.1280 | 0.1588 | 0.1107 | 0.1225 | 0.1340 | 0.1433 | 0.4752 | 0.3123 | 0.0008 | 0.0021 | 0.0061 | 0.0159 | 0.0445 | 0.0832 | 0.0794 | 0.1112 | 0.6569 | 15 | 19 | 23 | 31 | 50 | 98 | 191 | 331 | 581 | 0.0417 | 56.38 | 5.497 | 0.4839 | 134424.0 | 143000000 | 193000000000 | 306000000000000 | 0.3773 | 0.2809 | 0.0950 | 0.0031 | 0.2742 | 0.0340 | 0.2930 | 0.1903 | 0.1326 | 0.1923 | 0.0925 | 0.1954 | 0.0613 | 0.1542 | 0.0320 | 0.0969 | 0.0146 | 0.0718 | 0.0047 | 0.0620 | 0.0002 | 0.0002 | 0.0007 | 0.0005 | 0.0028 | 0.0019 | 0.0151 | 0.0118 | 0.0675 | 0.0598 | 0.1124 | 0.0965 | 0.0779 | 0.0655 | 0.1108 | 0.0997 | 0.6126 | 0.6642 | 0.0005 | 0.0011 | 0.0017 | 0.0024 | 0.0055 | 0.0069 | 0.0244 | 0.0283 | 0.0804 | 0.0894 | 0.1332 | 0.1361 | 0.0938 | 0.0992 | 0.1210 | 0.1267 | 0.5395 | 0.5097 | 0.0004 | 0.0016 | 0.0031 | 0.0214 | 0.0760 | 0.1177 | 0.0887 | 0.1187 | 0.5725 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1182 | 506 | | 5215 | 17071 | 251.9 | 54.05 | 103.06 | 163.53 | 180 | 201 | 217 | 233 | 250 | 266 | 282 | 302 | 327 | 0.0592 | 1011 | 1.075 | 113.14 | 33.02 | 1 | 0.0516 | 269 | 0.0008 | 48.54 | 7.272 | 0.1797 | 66392.4 | 18200000 | 5190000000 | 1520000000000 | 0.4330 | 0.2117 | 0.0006 | 0.0000 | 0.0022 | 0.0000 | 0.0048 | 0.0000 | 0.0275 | 0.0022 | 0.0797 | 0.0138 | 0.1232 | 0.0367 | 0.1331 | 0.0359 | 0.1574 | 0.0648 | 0.4715 | 0.8468 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0077 | 0.0012 | 0.0289 | 0.0106 | 0.0534 | 0.0245 | 0.0530 | 0.0168 | 0.0732 | 0.0315 | 0.7817 | 0.9154 | 0.0029 | 0.0373 | 0.0097 | 0.0683 | 0.0165 | 0.0683 | 0.0584 | 0.1739 | 0.1051 | 0.2050 | 0.1907 | 0.1801 | 0.1430 | 0.1180 | 0.1459 | 0.0745 | 0.3278 | 0.0745 | 0.0004 | 0.0027 | 0.0059 | 0.0212 | 0.0550 | 0.1037 | 0.0923 | 0.1127 | 0.6060 | 8 | 10 | 12 | 14 | 19 | 40 | 88 | 178 | 323 | 0.1315 | 17.54 | 4.370 | 0.5904 | 37361.8 | 20200000 | 13400000000 | 10300000000000 | 0.5718 | 0.1052 | 0.0904 | 0.0025 | 0.2461 | 0.0286 | 0.3176 | 0.1880 | 0.1451 | 0.1835 | 0.0925 | 0.1830 | 0.0641 | 0.1810 | 0.0273 | 0.0847 | 0.0137 | 0.0762 | 0.0032 | 0.0727 | 0.0004 | 0.0000 | 0.0008 | 0.0005 | 0.0013 | 0.0015 | 0.0144 | 0.0131 | 0.0649 | 0.0555 | 0.1011 | 0.0975 | 0.0663 | 0.0604 | 0.0930 | 0.0903 | 0.6578 | 0.6812 | 0.0005 | 0.0005 | 0.0016 | 0.0020 | 0.0060 | 0.0048 | 0.0196 | 0.0218 | 0.0670 | 0.0698 | 0.1097 | 0.1043 | 0.0649 | 0.0698 | 0.0947 | 0.0959 | 0.6360 | 0.6311 | 0.0004 | 0.0010 | 0.0042 | 0.0151 | 0.0692 | 0.1025 | 0.0681 | 0.0903 | 0.6491 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 325 | 775 | | 8514 | 19749 | 254.9 | 63.33 | 136.94 | 217.87 | 181 | 199 | 215 | 230 | 245 | 263 | 284 | 310 | 345 | 0.0554 | 1094 | 1.015 | 113.32 | 27.78 | 1 | 0.0297 | 253 | 0.0007 | 62.36 | 7.567 | 0.1617 | 68980.3 | 19800000 | 5980000000 | 1900000000000 | 0.4391 | 0.2068 | 0.0011 | 0.0003 | 0.0017 | 0.0003 | 0.0064 | 0.0005 | 0.0289 | 0.0021 | 0.0852 | 0.0200 | 0.1632 | 0.0545 | 0.1589 | 0.0468 | 0.1657 | 0.0841 | 0.3889 | 0.7914 | 0.0006 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0002 | 0.0093 | 0.0012 | 0.0318 | 0.0115 | 0.0627 | 0.0281 | 0.0665 | 0.0189 | 0.0802 | 0.0354 | 0.7455 | 0.9046 | 0.0011 | 0.0129 | 0.0048 | 0.0145 | 0.0117 | 0.0338 | 0.0490 | 0.0900 | 0.1087 | 0.1849 | 0.1695 | 0.2138 | 0.1317 | 0.1077 | 0.1359 | 0.1479 | 0.3875 | 0.1945 | 0.0016 | 0.0026 | 0.0085 | 0.0269 | 0.0708 | 0.1191 | 0.0930 | 0.1165 | 0.5610 | 12 | 14 | 16 | 18 | 24 | 48 | 109 | 230 | 450 | 0.0654 | 42.28 | 4.865 | 0.5213 | 66216.2 | 45500000 | 36800000000 | 33000000000000 | 0.5747 | 0.0897 | 0.0824 | 0.0046 | 0.2566 | 0.0341 | 0.3371 | 0.1863 | 0.1386 | 0.1780 | 0.0964 | 0.2125 | 0.0524 | 0.1720 | 0.0262 | 0.0876 | 0.0075 | 0.0710 | 0.0028 | 0.0539 | 0.0002 | 0.0005 | 0.0002 | 0.0002 | 0.0025 | 0.0009 | 0.0135 | 0.0136 | 0.0599 | 0.0488 | 0.1040 | 0.0963 | 0.0621 | 0.0576 | 0.0973 | 0.0891 | 0.6604 | 0.6931 | 0.0008 | 0.0018 | 0.0027 | 0.0016 | 0.0037 | 0.0040 | 0.0178 | 0.0162 | 0.0652 | 0.0702 | 0.1129 | 0.1134 | 0.0675 | 0.0720 | 0.1036 | 0.1107 | 0.6257 | 0.6101 | 0.0000 | 0.0009 | 0.0045 | 0.0148 | 0.0658 | 0.1032 | 0.0686 | 0.0979 | 0.6444 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 308 | 627 | | 7227 | 23465 | 215.5 | 41.93 | 145.25 | 174.73 | 162 | 178 | 191 | 202 | 212 | 224 | 237 | 252 | 273 | 0.0445 | 1045 | 1.162 | 108.98 | 41.15 | 1 | 0.0381 | 275 | 0.0011 | 40.67 | 7.077 | 0.1835 | 48189.1 | 11200000 | 2670000000 | 661000000000 | 0.4653 | 0.1920 | 0.0006 | 0.0000 | 0.0014 | 0.0000 | 0.0045 | 0.0000 | 0.0153 | 0.0013 | 0.0650 | 0.0143 | 0.1342 | 0.0316 | 0.1506 | 0.0321 | 0.1783 | 0.0507 | 0.4501 | 0.8700 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0054 | 0.0001 | 0.0288 | 0.0103 | 0.0653 | 0.0222 | 0.0624 | 0.0119 | 0.0865 | 0.0207 | 0.7501 | 0.9347 | 0.0050 | 0.0140 | 0.0231 | 0.0698 | 0.0330 | 0.1302 | 0.0759 | 0.1628 | 0.1485 | 0.1907 | 0.1774 | 0.1628 | 0.1238 | 0.0977 | 0.1493 | 0.1163 | 0.2640 | 0.0558 | 0.0014 | 0.0020 | 0.0084 | 0.0341 | 0.0981 | 0.1388 | 0.1119 | 0.1380 | 0.4672 | 12 | 14 | 17 | 26 | 56 | 119 | 196 | 282 | 392 | 0.0424 | 27.68 | 5.411 | 0.4772 | 51628.4 | 24900000 | 14400000000 | 9560000000000 | 0.4794 | 0.1582 | 0.0785 | 0.0020 | 0.2700 | 0.0215 | 0.3485 | 0.1855 | 0.1364 | 0.2031 | 0.0927 | 0.2112 | 0.0438 | 0.1640 | 0.0210 | 0.1007 | 0.0057 | 0.0672 | 0.0034 | 0.0448 | 0.0001 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0004 | 0.0088 | 0.0057 | 0.0525 | 0.0474 | 0.0960 | 0.0821 | 0.0705 | 0.0572 | 0.1013 | 0.0869 | 0.6700 | 0.7200 | 0.0001 | 0.0009 | 0.0013 | 0.0022 | 0.0034 | 0.0060 | 0.0176 | 0.0207 | 0.0700 | 0.0762 | 0.1210 | 0.1334 | 0.0883 | 0.0944 | 0.1155 | 0.1235 | 0.5829 | 0.5428 | 0.0000 | 0.0003 | 0.0021 | 0.0129 | 0.0602 | 0.1081 | 0.0860 | 0.1052 | 0.6252 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 329 | 607 | | 5771 | 20630 | 529.1 | 107.50 | 83.24 | 139.38 | 401 | 436 | 465 | 492 | 519 | 544 | 572 | 613 | 676 | 0.0490 | 1011 | 1.201 | 99.91 | 40.71 | 1 | 0.0452 | 261 | 0.0007 | 73.75 | 7.558 | 0.1339 | 291461.0 | 167000000 | 99900000000 | 62100000000000 | 0.4158 | 0.2294 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0031 | 0.0002 | 0.0148 | 0.0011 | 0.0604 | 0.0173 | 0.1177 | 0.0353 | 0.1405 | 0.0308 | 0.1599 | 0.0466 | 0.5026 | 0.8687 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0062 | 0.0000 | 0.0291 | 0.0118 | 0.0586 | 0.0242 | 0.0637 | 0.0139 | 0.0850 | 0.0235 | 0.7556 | 0.9266 | 0.0032 | 0.0079 | 0.0149 | 0.0277 | 0.0223 | 0.0316 | 0.0617 | 0.1067 | 0.1415 | 0.1225 | 0.1553 | 0.1858 | 0.0904 | 0.1225 | 0.1170 | 0.1304 | 0.3936 | 0.2648 | 0.0011 | 0.0023 | 0.0076 | 0.0345 | 0.0913 | 0.1330 | 0.1080 | 0.1258 | 0.4966 | 8 | 10 | 11 | 13 | 15 | 21 | 52 | 137 | 282 | 0.0906 | 17.39 | 4.254 | 0.5950 | 26353.8 | 12200000 | 6910000000 | 4480000000000 | 0.6077 | 0.0930 | 0.1055 | 0.0041 | 0.2829 | 0.0287 | 0.3598 | 0.1851 | 0.1526 | 0.2168 | 0.0596 | 0.2162 | 0.0335 | 0.1599 | 0.0037 | 0.0949 | 0.0025 | 0.0609 | 0.0000 | 0.0334 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0019 | 0.0016 | 0.0087 | 0.0077 | 0.0523 | 0.0454 | 0.0796 | 0.0732 | 0.0596 | 0.0497 | 0.0965 | 0.0851 | 0.7010 | 0.7371 | 0.0006 | 0.0002 | 0.0008 | 0.0018 | 0.0020 | 0.0042 | 0.0140 | 0.0178 | 0.0566 | 0.0567 | 0.1052 | 0.1144 | 0.0708 | 0.0696 | 0.1036 | 0.1054 | 0.6462 | 0.6299 | 0.0002 | 0.0004 | 0.0019 | 0.0113 | 0.0550 | 0.0902 | 0.0700 | 0.1005 | 0.6706 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 576 | 951 | | 438 | 2028 | 54.0 | 7.53 | 156.62 | 225.49 | 45 | 48 | 49 | 51 | 54 | 55 | 57 | 60 | 63 | 0.1686 | 342 | 0.895 | 78.01 | 22.20 | 1 | 0.4566 | 200 | 0.0096 | 10.55 | 4.855 | 0.3142 | 2971.3 | 166797 | 9560000 | 559000000 | 0.3875 | 0.2379 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0023 | 0.0262 | 0.0092 | 0.0945 | 0.0624 | 0.1260 | 0.0901 | 0.1811 | 0.0693 | 0.2520 | 0.1085 | 0.3123 | 0.6582 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0023 | 0.0193 | 0.0091 | 0.0578 | 0.0594 | 0.0988 | 0.0868 | 0.1012 | 0.0548 | 0.1518 | 0.0868 | 0.5639 | 0.7009 | 0.1765 | 0.0000 | 0.1765 | 0.2000 | 0.0588 | 0.2000 | 0.1765 | 0.6000 | 0.1176 | 0.0000 | 0.0294 | 0.0000 | 0.1765 | 0.0000 | 0.0882 | 0.0000 | 0.0000 | 0.0000 | 0.0136 | 0.0318 | 0.0227 | 0.0773 | 0.1364 | 0.1364 | 0.1500 | 0.2091 | 0.2227 | 17 | 21 | 28 | 41 | 64 | 99 | 142 | 241 | 425 | 0.0260 | 58.20 | 5.100 | 0.4350 | 75349.7 | 58100000 | 55000000000 | 57800000000000 | 0.4831 | 0.1439 | 0.1056 | 0.0000 | 0.2609 | 0.0221 | 0.2050 | 0.1838 | 0.0870 | 0.1569 | 0.1242 | 0.1936 | 0.0870 | 0.1201 | 0.0683 | 0.0760 | 0.0435 | 0.1176 | 0.0186 | 0.1299 | 0.0030 | 0.0000 | 0.0030 | 0.0036 | 0.0151 | 0.0059 | 0.0256 | 0.0119 | 0.0935 | 0.0973 | 0.1704 | 0.1269 | 0.0905 | 0.0973 | 0.1297 | 0.1329 | 0.4691 | 0.5243 | 0.0020 | 0.0000 | 0.0060 | 0.0069 | 0.0159 | 0.0207 | 0.0239 | 0.0345 | 0.1076 | 0.1310 | 0.1853 | 0.1816 | 0.1036 | 0.0989 | 0.1474 | 0.1402 | 0.4084 | 0.3862 | 0.0000 | 0.0035 | 0.0159 | 0.0265 | 0.1044 | 0.1805 | 0.0973 | 0.1274 | 0.4442 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 84 | 350 | | 635 | 11961 | 63.2 | 10.04 | 161.70 | 197.63 | 50 | 54 | 57 | 61 | 63 | 66 | 68 | 71 | 76 | 0.0579 | 693 | 0.875 | 142.76 | 45.97 | 2 | 0.6299 | 400 | 0.0068 | 11.22 | 5.192 | 0.3174 | 4092.7 | 271580 | 18400000 | 1280000000 | 0.4246 | 0.2192 | 0.0020 | 0.0000 | 0.0061 | 0.0016 | 0.0242 | 0.0048 | 0.0364 | 0.0111 | 0.0667 | 0.0430 | 0.1091 | 0.0685 | 0.1172 | 0.0525 | 0.1960 | 0.0812 | 0.4424 | 0.7373 | 0.0018 | 0.0000 | 0.0053 | 0.0016 | 0.0124 | 0.0047 | 0.0284 | 0.0110 | 0.0443 | 0.0379 | 0.0585 | 0.0694 | 0.0709 | 0.0394 | 0.0816 | 0.0599 | 0.6968 | 0.7760 | 0.0580 | 0.3333 | 0.0870 | 0.0000 | 0.1594 | 0.3333 | 0.0725 | 0.3333 | 0.1739 | 0.0000 | 0.0870 | 0.0000 | 0.0580 | 0.0000 | 0.1014 | 0.0000 | 0.2029 | 0.0000 | 0.0060 | 0.0030 | 0.0328 | 0.0448 | 0.0836 | 0.1045 | 0.1104 | 0.1761 | 0.4388 | 14 | 18 | 22 | 31 | 58 | 116 | 205 | 315 | 458 | 0.0352 | 28.43 | 5.403 | 0.4619 | 65200.6 | 35400000 | 22500000000 | 16100000000000 | 0.5927 | 0.1032 | 0.1018 | 0.0034 | 0.2284 | 0.0353 | 0.3243 | 0.1826 | 0.1467 | 0.1894 | 0.1089 | 0.2031 | 0.0462 | 0.1570 | 0.0249 | 0.0990 | 0.0130 | 0.0728 | 0.0059 | 0.0575 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0020 | 0.0022 | 0.0142 | 0.0124 | 0.0583 | 0.0519 | 0.0965 | 0.0944 | 0.0720 | 0.0609 | 0.0991 | 0.0924 | 0.6569 | 0.6855 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0029 | 0.0060 | 0.0195 | 0.0279 | 0.0776 | 0.0835 | 0.1193 | 0.1370 | 0.0921 | 0.0943 | 0.1271 | 0.1346 | 0.5598 | 0.5161 | 0.0002 | 0.0002 | 0.0027 | 0.0176 | 0.0677 | 0.1015 | 0.0832 | 0.1135 | 0.6134 |